Detailed information for compound 30221

Basic information

Technical information
  • TDR Targets ID: 30221
  • Name: (2S)-2-(butylsulfonylamino)-3-[(9-pyridin-4-y l-9-azaspiro[5.5]undecane-3-carbonyl)amino]pr opanoic acid
  • MW: 480.621 | Formula: C23H36N4O5S
  • H donors: 3 H acceptors: 6 LogP: 2.42 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCS(=O)(=O)N[C@H](C(=O)O)CNC(=O)C1CCC2(CC1)CCN(CC2)c1ccncc1
  • InChi: 1S/C23H36N4O5S/c1-2-3-16-33(31,32)26-20(22(29)30)17-25-21(28)18-4-8-23(9-5-18)10-14-27(15-11-23)19-6-12-24-13-7-19/h6-7,12-13,18,20,26H,2-5,8-11,14-17H2,1H3,(H,25,28)(H,29,30)/t20-/m0/s1
  • InChiKey: WIZNRUGPDHNTSZ-FQEVSTJZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)-9-azaspiro[5.5]undecane-3-carbonyl]amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[oxo-[9-(4-pyridyl)-9-azaspiro[5.5]undecan-3-yl]methyl]amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[(9-pyridin-4-yl-9-azaspiro[5.5]undecan-3-yl)carbonylamino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)-9-azaspiro[5.5]undecane-3-carbonyl]amino]propionic acid
  • (2S)-2-(butylsulfonylamino)-3-[(9-pyridin-4-yl9-azaspiro[5.5]undecane-3-carbonyl)amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)9-azaspiro[5.5]undecane-3-carbonyl]amino]propanoic acid
  • (2S)-2-(butylsulfonylamino)-3-[[9-(4-pyridyl)9-azaspiro[5.5]undecane-3-carbonyl]amino]propionic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) Starlite/ChEMBL References
Homo sapiens integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus multilocularis integrin beta 2 Get druggable targets OG5_127959 All targets in OG5_127959
Brugia malayi Integrin alpha pat-2 precursor Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06476 integrin alpha 2B, putative Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) integrin beta-2 Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum Integrin beta-3 precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum IPR013513,Integrin alpha chain, C-terminal cytoplasmic region,domain-containing Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus multilocularis integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Echinococcus granulosus integrin alpha 3 Get druggable targets OG5_129341 All targets in OG5_129341
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129341 All targets in OG5_129341
Brugia malayi Integrin beta pat-3 precursor Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma mansoni integrin alpha Get druggable targets OG5_129341 All targets in OG5_129341
Schistosoma japonicum ko:K06464 integrin beta 2, putative Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma japonicum Integrin beta-PS precursor, putative Get druggable targets OG5_127959 All targets in OG5_127959
Schistosoma mansoni integrin beta subunit Get druggable targets OG5_127959 All targets in OG5_127959
Loa Loa (eye worm) integrin alpha pat-2 Get druggable targets OG5_129341 All targets in OG5_129341
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0421 0.0781 0.1851
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.3845 0.768 0.7679
Schistosoma mansoni cathepsin D (A01 family) 0.0338 0.0614 0.0614
Entamoeba histolytica calpain family cysteine protease, putative 0.0421 0.0781 0.2735
Plasmodium falciparum plasmepsin IX 0.0297 0.0532 0.1861
Schistosoma mansoni Mername-AA248 (C02 family) 0.144 0.2834 0.2834
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0384 0.0706 0.1968
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.0013 0.0041
Schistosoma mansoni calpain-7 (C02 family) 0.1443 0.284 0.284
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Plasmodium vivax plasmepsin V, putative 0.0054 0.0042 0.0143
Onchocerca volvulus 0.0046 0.0025 0.0032
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0258 0.0452 0.0452
Trichomonas vaginalis centrin, putative 0.023 0.0397 0.1104
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0248 0.0432 0.1202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trypanosoma brucei mitochondrial calcium uptake 1 0.023 0.0397 0.0938
Schistosoma mansoni hypothetical protein 0.0181 0.0298 0.0298
Schistosoma mansoni hypothetical protein 0.0181 0.0298 0.0298
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0285 0.0508 0.0508
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0234 0.0405 0.0405
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0013 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Onchocerca volvulus 0.0046 0.0025 0.0032
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0248 0.0432 0.043
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0023 0.0021
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.0013 0.0041
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0384 0.0706 0.2471
Trypanosoma cruzi histone deacetylase 1, putative 0.0093 0.012 0.0118
Trichomonas vaginalis calcium binding protein, putative 0.0238 0.0411 0.1145
Toxoplasma gondii peptidase family M13 protein 0.0099 0.0132 0.031
Echinococcus multilocularis cathepsin b 0.4997 1 1
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Brugia malayi proteasome subunit alpha type 1 0.004 0.0013 0.0012
Leishmania major protein kinase, putative 0.023 0.0397 0.0938
Brugia malayi histone deacetylase 1 (HD1) 0.0093 0.012 0.0118
Giardia lamblia 20S proteasome alpha subunit 2 0.004 0.0013 0.0033
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0012 0.0037
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0022
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.004 0.0013 0.0012
Brugia malayi Peroxidasin 0.0281 0.0499 0.0497
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.0013 0.0041
Brugia malayi Pepsin A precursor 0.0054 0.0042 0.0041
Giardia lamblia Glycogen phosphorylase 0.0117 0.0169 0.0466
Echinococcus granulosus proteasome prosome macropain subunit beta 0.009 0.0114 0.0114
Onchocerca volvulus 0.0281 0.0499 0.1026
Loa Loa (eye worm) peptidase family M13 containing protein 0.0073 0.008 0.0078
Trypanosoma cruzi prolyl endopeptidase 0.2125 0.4213 0.4212
Trichomonas vaginalis conserved hypothetical protein 0.0421 0.0781 0.2178
Loa Loa (eye worm) programmed cell death protein 6 0.0234 0.0405 0.0403
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0688 0.1319 0.1319
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0223 0.0223
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Trichomonas vaginalis calmodulin, putative 0.0238 0.0411 0.1145
Trypanosoma cruzi calpain cysteine peptidase, putative 0.144 0.2834 0.2833
Giardia lamblia Hypothetical protein 0.0384 0.0706 0.1968
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Echinococcus multilocularis EF HAND 1, calcium binding site 0.023 0.0397 0.0397
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0064 0.0061 0.0059
Echinococcus granulosus calpain 7 C02 family 0.144 0.2834 0.2834
Echinococcus multilocularis calcium uptake protein 1 0.0234 0.0405 0.0405
Giardia lamblia Hypothetical protein 0.0384 0.0706 0.1968
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Leishmania major proteasome beta-1 subunit, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Leishmania major silent information regulator 2, putative 0.0258 0.0452 0.107
Trypanosoma brucei hypothetical protein, conserved 0.023 0.0397 0.0938
Loa Loa (eye worm) hypothetical protein 0.0049 0.0031 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.004 0.0013 0.0028
Trypanosoma brucei hypothetical protein 0.0421 0.0781 0.1851
Brugia malayi calcium-binding protein 0.023 0.0397 0.0395
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Echinococcus multilocularis tissue type plasminogen activator 0.007 0.0075 0.0075
Onchocerca volvulus 0.0046 0.0025 0.0032
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.004 0.0013 0.0011
Echinococcus granulosus prolyl endopeptidase 0.2125 0.4213 0.4213
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Loa Loa (eye worm) aspartyl protease 6 0.0054 0.0042 0.0041
Brugia malayi Cathepsin L-like precursor 0.0432 0.0803 0.0801
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Schistosoma mansoni histone deacetylase hda2 0.0111 0.0156 0.0156
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0896 0.1739 1
Brugia malayi Pre-SET motif family protein 0.01 0.0135 0.0133
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.023 0.0397 0.0395
Loa Loa (eye worm) proteasome subunit beta type 1 0.0142 0.0219 0.0217
Brugia malayi Papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.023 0.0397 0.1386
Loa Loa (eye worm) peptidase family M13 containing protein 0.0073 0.008 0.0078
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0867 0.168 0.168
Onchocerca volvulus 0.0181 0.0298 0.0605
Trypanosoma brucei calmodulin, putative 0.023 0.0397 0.0938
Schistosoma mansoni histone deacetylase 0.0093 0.012 0.012
Trichomonas vaginalis calpain, putative 0.0421 0.0781 0.2178
Trypanosoma cruzi kinesin, putative 0.1019 0.1985 0.1984
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Echinococcus multilocularis glycogen phosphorylase 0.0117 0.0169 0.0169
Toxoplasma gondii proteasome subunit 0.004 0.0013 0.0028
Leishmania major calmodulin-like protein 0.023 0.0397 0.0938
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0009 0.0009
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Onchocerca volvulus Notchless protein homolog 0.004 0.0013 0.0008
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.004 0.0013 0.0041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Onchocerca volvulus Legumain homolog 0.0147 0.023 0.0462
Loa Loa (eye worm) blistered cuticle protein 3 0.0281 0.0499 0.0497
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0384 0.0706 0.2471
Brugia malayi Histone deacetylase family protein 0.0104 0.0143 0.0141
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0688 0.1319 0.3128
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Brugia malayi Serine protease Z688.6 precursor 0.0064 0.0061 0.0059
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0064 0.0061 0.0059
Trypanosoma cruzi calmodulin, putative 0.023 0.0397 0.0395
Brugia malayi Peptidase C13 family protein 0.0147 0.023 0.0228
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.2125 0.4213 1
Echinococcus granulosus caspase 8 0.014 0.0214 0.0214
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Plasmodium vivax aspartyl protease, putative 0.0297 0.0532 0.1861
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0064 0.0061 0.0208
Giardia lamblia Hypothetical protein 0.0258 0.0452 0.1259
Echinococcus multilocularis cathepsin L cysteine protease 0.1449 0.2852 0.2852
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1449 0.2852 0.2851
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2125 0.4213 0.4213
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0816 0.1576 0.1576
Brugia malayi beta-lactamase 0.0038 0.0009 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1449 0.2852 0.7966
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0688 0.1319 0.3128
Loa Loa (eye worm) histone deacetylase 11 0.0045 0.0023 0.0021
Plasmodium vivax unspecified product 0.0384 0.0706 0.2471
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0013 0.0028
Plasmodium vivax serine-repeat antigen (SERA) 0.0384 0.0706 0.2471
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Trypanosoma cruzi cruzipain precursor, putative 0.1505 0.2964 0.2963
Echinococcus multilocularis calpain 5 0.144 0.2834 0.2834
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1449 0.2852 0.2852
Echinococcus granulosus proteasome subunit beta type 7 0.004 0.0013 0.0013
Brugia malayi hypothetical protein 0.0178 0.0292 0.029
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Trypanosoma brucei proteasome beta-1 subunit, putative 0.004 0.0013 0.0028
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.0013 0.0012
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.0114 0.0114
Trypanosoma brucei proteasome beta 6 subunit 0.0142 0.0219 0.0516
Echinococcus multilocularis expressed protein 0.0441 0.082 0.082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0384 0.0706 0.0706
Plasmodium vivax proteasome subunit alpha type-2, putative 0.004 0.0013 0.0041
Leishmania major hypothetical protein, conserved 0.0234 0.0405 0.0957
Onchocerca volvulus 0.0182 0.03 0.0609
Leishmania major cathepsin L-like protease 0.1505 0.2964 0.7034
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Leishmania major programmed cell death 6 protein-like protein 0.023 0.0397 0.0938
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.0013 0.0028
Echinococcus multilocularis calmodulin 0.023 0.0397 0.0397
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Mycobacterium ulcerans transglutaminase family protein 0.0443 0.0824 0.4712
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Schistosoma mansoni survival motor neuron protein 0.0056 0.0046 0.0046
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0012 0.0025
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.004 0.0013 0.0013
Echinococcus granulosus EF hand domain containing family member A2 0.023 0.0397 0.0397
Echinococcus granulosus Dipeptidyl peptidase 9 0.0688 0.1319 0.1319
Echinococcus granulosus calbindin 32 0.0234 0.0405 0.0405
Echinococcus multilocularis endothelin converting enzyme 1 0.0099 0.0132 0.0132
Leishmania major centrin, putative,caltractin, putative 0.023 0.0397 0.0938
Giardia lamblia Proteasome subunit beta type 4 precursor 0.004 0.0013 0.0033
Echinococcus multilocularis cysteine protease 0.1449 0.2852 0.2852
Entamoeba histolytica prolyl oligopeptidase family protein 0.0299 0.0536 0.1874
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0009 0.0022
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Loa Loa (eye worm) calpain family protein 1 0.3845 0.768 0.7679
Trypanosoma brucei Metacaspase-4 0.014 0.0214 0.0504
Onchocerca volvulus 0.0281 0.0499 0.1026
Plasmodium vivax proteasome subunit beta type-5, putative 0.0248 0.0432 0.1509
Schistosoma mansoni hypothetical protein 0.023 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trypanosoma brucei proteasome beta 3 subunit, putative 0.004 0.0013 0.0028
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3845 0.768 0.768
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.004 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.01 0.0135 0.0135
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0191 0.0318 0.0318
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0384 0.0706 0.1968
Schistosoma mansoni cathepsin S (C01 family) 0.0384 0.0706 0.0706
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.014 0.0214 0.0214
Brugia malayi Histone deacetylase family protein 0.0104 0.0143 0.0141
Leishmania major sir2-family protein-like protein 0.0066 0.0066 0.0154
Plasmodium falciparum plasmepsin II 0.0054 0.0042 0.0143
Entamoeba histolytica histone deacetylase, putative 0.0093 0.012 0.0415
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.023 0.0397 0.0938
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Entamoeba histolytica glycogen phosphorylase, putative 0.0117 0.0169 0.0586
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Onchocerca volvulus 0.0046 0.0025 0.0032
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0064 0.0061 0.0166
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0064 0.0061 0.0208
Onchocerca volvulus 0.1449 0.2852 0.5961
Echinococcus granulosus acylamino acid releasing enzyme 0.0299 0.0536 0.0536
Trypanosoma brucei centrin-3 0.0238 0.0411 0.0973
Loa Loa (eye worm) hypothetical protein 0.007 0.0075 0.0073
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.004 0.0013 0.0041
Brugia malayi 20S proteasome alpha5 subunit 0.004 0.0013 0.0012
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0066 0.0066 0.0227
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Trichomonas vaginalis set domain proteins, putative 0.0792 0.1528 0.4264
Onchocerca volvulus 0.1017 0.1982 0.4137
Brugia malayi calpain D 0.0421 0.0781 0.078
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.2826 0.5627 0.5626
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0009 0.0009
Leishmania major histone deacetylase, putative 0.0093 0.012 0.0281
Onchocerca volvulus Prolyl endopeptidase homolog 0.2125 0.4213 0.8815
Schistosoma mansoni caspase-3 (C14 family) 0.0426 0.0791 0.0791
Echinococcus multilocularis chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Brugia malayi hypothetical protein 0.0054 0.0042 0.0041
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0012 0.003
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.0013 0.0041
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0009 0.0008
Mycobacterium tuberculosis Conserved hypothetical protein 0.0443 0.0824 0.2263
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Entamoeba histolytica hypothetical protein, conserved 0.0066 0.0066 0.0227
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4075 0.8144 0.8144
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0258 0.0452 0.0452
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.01 0.0135 0.0135
Echinococcus multilocularis cathepsin L 0.0816 0.1576 0.1576
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.01 0.0135 0.0316
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0142 0.0219 0.0217
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0258 0.0452 0.1581
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi conserved protein 0.0421 0.0781 0.078
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.009 0.0114 0.0395
Echinococcus granulosus histone deacetylase 6 0.0104 0.0143 0.0143
Trypanosoma cruzi cysteine proteinase, putative 0.0816 0.1576 0.1575
Echinococcus granulosus Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Brugia malayi programmed cell death protein 6 0.023 0.0397 0.0395
Toxoplasma gondii microneme protein MIC4 0.0046 0.0025 0.0054
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.023 0.0397 0.1386
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0009 0.0009
Onchocerca volvulus Cathepsin F homolog 0.1449 0.2852 0.5961
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Echinococcus granulosus cathepsin l cysteine peptidase 0.1449 0.2852 0.2852
Plasmodium falciparum calpain 0.0421 0.0781 0.2735
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0384 0.0706 0.1968
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0054 0.0042 0.0042
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Leishmania major proteasome alpha 3 subunit, putative 0.004 0.0013 0.0028
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Schistosoma mansoni peroxidasin 0.0281 0.0499 0.0499
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.0013 0.0012
Schistosoma mansoni ef hand domain family member A2 0.023 0.0397 0.0397
Loa Loa (eye worm) PAS-3 protein 0.004 0.0013 0.0012
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.078
Trichomonas vaginalis conserved hypothetical protein 0.0299 0.0536 0.1493
Trichomonas vaginalis centrin, putative 0.023 0.0397 0.1104
Loa Loa (eye worm) hypothetical protein 0.0277 0.0491 0.049
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0012 0.003
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0432 0.0803 0.0801
Loa Loa (eye worm) hypothetical protein 0.037 0.0678 0.0676
Giardia lamblia Proteasome subunit beta type 9 precursor 0.004 0.0013 0.0033
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Plasmodium vivax aspartyl proteinase, putative 0.0054 0.0042 0.0143
Schistosoma mansoni aldehyde dehydrogenase 0.0141 0.0217 0.0217
Brugia malayi cathepsin Z-like cysteine proteinase 0.0384 0.0706 0.0704
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0384 0.0706 0.0704
Toxoplasma gondii aspartyl protease ASP1 0.0054 0.0042 0.0097
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.004 0.0013 0.0041
Onchocerca volvulus 0.0181 0.0298 0.0605
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0248 0.0432 0.1173
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Plasmodium falciparum histone deacetylase 1 0.0093 0.012 0.0415
Loa Loa (eye worm) hypothetical protein 0.0043 0.002 0.0018
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0299 0.0536 0.1874
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Plasmodium vivax SET domain protein, putative 0.01 0.0135 0.0468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) proteasome subunit alpha type 6 0.004 0.0013 0.0012
Trypanosoma brucei kinesin, putative 0.1019 0.1985 0.471
Echinococcus granulosus integrin beta 2 0.028 0.0497 0.0497
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.1062 0.2073 0.4327
Giardia lamblia Serine peptidase, putative 0.0064 0.0061 0.0166
Onchocerca volvulus 0.023 0.0397 0.0812
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Toxoplasma gondii prolyl endopeptidase 0.2125 0.4213 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0093 0.012 0.0118
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Schistosoma mansoni calpain (C02 family) 0.144 0.2834 0.2834
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0384 0.0706 0.2471
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0816 0.1576 0.3738
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.0217 0.1198
Echinococcus granulosus integrin alpha ps 0.0083 0.01 0.01
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0093 0.012 0.0118
Plasmodium falciparum proteasome subunit beta type-6, putative 0.004 0.0013 0.0041
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0066 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0099 0.0132 0.013
Loa Loa (eye worm) ctsf protein 0.1449 0.2852 0.2851
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0181 0.0298 0.0298
Entamoeba histolytica calpain large subunit domain III containing protein 0.1019 0.1985 0.6959
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Giardia lamblia Sirtuin type 2 0.0066 0.0066 0.0181
Echinococcus multilocularis calbindin 32 0.0234 0.0405 0.0405
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Giardia lamblia Proteasome subunit beta type 3 0.004 0.0013 0.0033
Toxoplasma gondii calcium-dependent protein kinase 0.0234 0.0405 0.0957
Schistosoma mansoni hypothetical protein 0.0443 0.0824 0.0824
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.023 0.0397 0.0395
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0046 0.0044
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Brugia malayi prolyl oligopeptidase family protein 0.0688 0.1319 0.1318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Schistosoma mansoni chromatin regulatory protein sir2 0.0285 0.0508 0.0508
Schistosoma mansoni chromatin regulatory protein sir2 0.0066 0.0066 0.0066
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0299 0.0536 0.0536
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.004 0.0013 0.0028
Trypanosoma brucei Calpain-like protein 1.2 0.0421 0.0781 0.1851
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0182 0.03 0.0298
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Trypanosoma cruzi major cysteine proteinase, putative 0.0439 0.0818 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi Aph-1 protein, putative 0.0105 0.0145 0.0143
Entamoeba histolytica hypothetical protein, conserved 0.0234 0.0405 0.1414
Onchocerca volvulus 0.1449 0.2852 0.5961
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0066 0.0227
Schistosoma mansoni Nep2 peptidase (M13 family) 0.005 0.0033 0.0033
Plasmodium vivax proteasome subunit beta type-3, putative 0.004 0.0013 0.0041
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Leishmania major proteasome alpha 7 subunit, putative 0.004 0.0013 0.0028
Toxoplasma gondii histone deacetylase HDAC4 0.0045 0.0023 0.0051
Schistosoma mansoni cathepsin s 0.0432 0.0803 0.0803
Brugia malayi Papain family cysteine protease containing protein 0.0816 0.1576 0.1575
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Echinococcus granulosus chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Schistosoma mansoni integrin beta subunit 0.0223 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0322 0.0581 0.058
Plasmodium vivax unspecified product 0.0432 0.0803 0.2811
Schistosoma mansoni reticulocalbin 0.0234 0.0405 0.0405
Trichomonas vaginalis calmodulin, putative 0.0234 0.0405 0.1126
Onchocerca volvulus 0.0046 0.0025 0.0032
Loa Loa (eye worm) glycogen phosphorylase 0.0117 0.0169 0.0167
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1449 0.2852 0.2851
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0191 0.0318 0.0316
Brugia malayi histone deacetylase 3 (HD3) 0.0093 0.012 0.0118
Giardia lamblia Cathepsin B precursor 0.181 0.358 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Onchocerca volvulus 0.0181 0.0298 0.0605
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0012 0.0011
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.004 0.0013 0.0041
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0012 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1017 0.1982 0.5534
Loa Loa (eye worm) sirtuin 4 0.0066 0.0066 0.0065
Entamoeba histolytica glycogenphosphorylase, putative 0.0051 0.0035 0.0116
Giardia lamblia Cathepsin B precursor 0.181 0.358 1
Onchocerca volvulus 0.0046 0.0025 0.0032
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0577 0.1094 0.2594
Brugia malayi proteasome subunit alpha type 6 0.004 0.0013 0.0012
Echinococcus granulosus microtubule associated protein 2 0.0796 0.1536 0.1536
Echinococcus granulosus proteasome subunit beta type 6 0.004 0.0013 0.0013
Onchocerca volvulus Peroxidasin homolog 0.0281 0.0499 0.1026
Echinococcus granulosus histone deacetylase 6 0.0111 0.0156 0.0156
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Onchocerca volvulus Peroxidase homolog 0.0281 0.0499 0.1026
Loa Loa (eye worm) TK/ROR protein kinase 0.007 0.0075 0.0073
Toxoplasma gondii proteasome subunit alpha type, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.004 0.0013 0.0028
Echinococcus granulosus 20S proteasome subunit alpha 6 0.004 0.0013 0.0013
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0696 0.1334 0.1333
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0012 0.0025
Trypanosoma brucei metacaspase MCA2 0.014 0.0214 0.0504
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.078
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.004 0.0013 0.0013
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0023 0.0021
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.4075 0.8144 0.8144
Schistosoma mansoni histone deacetylase 4 5 0.0104 0.0143 0.0143
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Onchocerca volvulus 0.1449 0.2852 0.5961
Brugia malayi hypothetical protein 0.0276 0.0488 0.0487
Onchocerca volvulus 0.0281 0.0499 0.1026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.0217 0.1198
Plasmodium falciparum proteasome subunit beta type-2, putative 0.009 0.0114 0.0395
Schistosoma mansoni hypothetical protein 0.007 0.0075 0.0075
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0093 0.012 0.033
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0223 0.0223
Schistosoma mansoni histone deacetylase 4 5 0.0104 0.0143 0.0143
Entamoeba histolytica hypothetical protein 0.0384 0.0706 0.2471
Trypanosoma brucei Calpain-like protein CALP1.3 0.0421 0.0781 0.1851
Trypanosoma cruzi centrin, putative 0.0238 0.0411 0.041
Echinococcus granulosus programmed cell death protein 0.0238 0.0411 0.0411
Trichomonas vaginalis calpain, putative 0.0421 0.0781 0.2178
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0397 0.1104
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Loa Loa (eye worm) hypothetical protein 0.1017 0.1982 0.1981
Trypanosoma cruzi hypothetical protein, conserved 0.0299 0.0536 0.0534
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.1185 0.2319 0.2319
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Trypanosoma brucei C-8 sterol isomerase, putative 0.037 0.0678 0.1605
Echinococcus granulosus proteasome subunit beta t family 0.004 0.0013 0.0013
Onchocerca volvulus Peroxidase homolog 0.0281 0.0499 0.1026
Schistosoma mansoni integrin alpha 0.0185 0.0305 0.0305
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Giardia lamblia Alanyl dipeptidyl peptidase 0.0299 0.0536 0.1493
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Plasmodium falciparum serine repeat antigen 2 0.0384 0.0706 0.2471
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.0013 0.0012
Trypanosoma brucei prolyl oligopeptidase, putative 0.0896 0.1739 0.4125
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Plasmodium vivax vivapain-2 0.1449 0.2852 1
Echinococcus granulosus expressed protein 0.0441 0.082 0.082
Plasmodium vivax vivapain-1 0.0816 0.1576 0.5523
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.0013 0.0028
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Trypanosoma cruzi I/6 autoantigen, putative 0.023 0.0397 0.0395
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0009 0.0027
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Loa Loa (eye worm) hypothetical protein 0.0191 0.0318 0.0316
Onchocerca volvulus 0.0181 0.0298 0.0605
Toxoplasma gondii histone deacetylase HDAC3 0.0093 0.012 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0816 0.1576 0.4399
Toxoplasma gondii microneme protein MIC17A 0.0046 0.0025 0.0054
Leishmania major cathepsin L-like protease 0.1505 0.2964 0.7034
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.181 0.358 0.8497
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0384 0.0706 0.0704
Entamoeba histolytica cysteine proteinase 1, putative 0.0816 0.1576 0.5523
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Echinococcus granulosus caspase 0.0426 0.0791 0.0791
Plasmodium falciparum histone deacetylase 2 0.0104 0.0143 0.0495
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Echinococcus multilocularis peroxidasin 0.0281 0.0499 0.0499
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0093 0.012 0.033
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.009 0.0114 0.0113
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0051 0.0035 0.0146
Loa Loa (eye worm) hypothetical protein 0.0432 0.0803 0.0801
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0688 0.1319 0.1319
Schistosoma mansoni caspase-7 (C14 family) 0.0426 0.0791 0.0791
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Echinococcus granulosus histone deacetylase 6 0.0104 0.0143 0.0143
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0066 0.0066 0.0065
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Brugia malayi Proteasome A-type and B-type family protein 0.0248 0.0432 0.043
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0066 0.0066 0.0154
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Toxoplasma gondii histone deacetylase SIR2-like 0.0066 0.0066 0.0154
Plasmodium falciparum metacaspase-like protein 0.014 0.0214 0.0745
Echinococcus multilocularis histone deacetylase 3 0.0093 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0012 0.0008
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.4075 0.8144 0.8144
Trypanosoma brucei centrin, putative 0.023 0.0397 0.0938
Loa Loa (eye worm) prolyl oligopeptidase 0.1062 0.2073 0.2071
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Leishmania major kinesin, putative 0.1019 0.1985 0.471
Plasmodium falciparum plasmepsin VIII, putative 0.0054 0.0042 0.0143
Echinococcus granulosus cathepsin b 0.4997 1 1
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.023 0.0397 0.1386
Loa Loa (eye worm) cathepsin B 0.181 0.358 0.3579
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0013 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0384 0.0706 0.1968
Onchocerca volvulus 0.0046 0.0025 0.0032
Leishmania major cysteine peptidase A (CPA) 0.1449 0.2852 0.6768
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Trypanosoma brucei protein I/6 0.023 0.0397 0.0938
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Echinococcus granulosus calpain A 0.4079 0.8151 0.8151
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Echinococcus multilocularis EF hand domain containing family member A2 0.023 0.0397 0.0397
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Entamoeba histolytica cysteine proteinase, putative 0.1449 0.2852 1
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0023 0.0023
Echinococcus multilocularis geminin 0.0177 0.0289 0.0289
Toxoplasma gondii cathepsin CPC2 0.0384 0.0706 0.1672
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Loa Loa (eye worm) fibroinase 0.1449 0.2852 0.2851
Trypanosoma brucei calmodulin, putative 0.0234 0.0405 0.0957
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Toxoplasma gondii proteasome subunit alpha1, putative 0.004 0.0013 0.0028
Giardia lamblia 20S proteasome alpha subunit 3 0.004 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0182 0.03 0.03
Plasmodium vivax proteasome subunit alpha type-5, putative 0.004 0.0013 0.0041
Plasmodium falciparum serine repeat antigen 1 0.0384 0.0706 0.2471
Trypanosoma cruzi oligopeptidase b 0.0896 0.1739 0.1737
Plasmodium falciparum proteasome subunit beta type-7, putative 0.004 0.0013 0.0041
Echinococcus multilocularis integrin alpha ps 0.004 0.0013 0.0013
Schistosoma mansoni peroxidasin 0.0281 0.0499 0.0499
Echinococcus granulosus calpain A 0.144 0.2834 0.2834
Giardia lamblia Encystation-specific protease 0.0384 0.0706 0.1968
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Echinococcus granulosus calpain 5 0.144 0.2834 0.2834
Loa Loa (eye worm) proteasome subunit beta type 3 0.004 0.0013 0.0012
Giardia lamblia Cathepsin L-like protease 0.0384 0.0706 0.1968
Brugia malayi hypothetical protein 0.0057 0.0049 0.0047
Leishmania major hypothetical protein, conserved 0.007 0.0075 0.0174
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0142 0.0219 0.0516
Echinococcus multilocularis calpain 0.144 0.2834 0.2834
Schistosoma mansoni hypothetical protein 0.045 0.0839 0.0839
Trypanosoma brucei histone deacetylase 3 0.0104 0.0143 0.0335
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0258 0.0452 0.1259
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0299 0.0536 0.1268
Loa Loa (eye worm) hypothetical protein 0.01 0.0135 0.0133
Trichomonas vaginalis glycogen phosphorylase, putative 0.0117 0.0169 0.0466
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.2125 0.4213 0.4213
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0114 0.0315
Echinococcus multilocularis calpain 7 (C02 family) 0.144 0.2834 0.2834
Onchocerca volvulus 0.2405 0.4778 1
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0061 0.0166
Echinococcus multilocularis cathepsin L cysteine protease 0.1449 0.2852 0.2852
Schistosoma mansoni chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Schistosoma mansoni neprilysin-2 (M13 family) 0.005 0.0033 0.0033
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1449 0.2852 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0384 0.0706 0.2471
Trypanosoma cruzi metacaspase 5, putative 0.014 0.0214 0.0212
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Plasmodium vivax proteasome subunit beta type-1, putative 0.0142 0.0219 0.0763
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0191 0.0318 0.0318
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Trypanosoma brucei Calpain-like protein 2 0.0421 0.0781 0.1851
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Onchocerca volvulus Peroxidasin homolog 0.0281 0.0499 0.1026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Mycobacterium leprae Conserved hypothetical protein 0.0443 0.0824 0.4712
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0064 0.0061 0.0208
Loa Loa (eye worm) hypothetical protein 0.0276 0.0488 0.0487
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4997 1 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.1017 0.1982 0.1981
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0299 0.0536 0.0536
Echinococcus granulosus cysteine protease 0.0816 0.1576 0.1576
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.004 0.0013 0.0041
Trypanosoma brucei calpain, putative 0.0421 0.0781 0.1851
Brugia malayi NAD-dependent deacetylase SIRT1 0.0285 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0432 0.0803 0.0801
Brugia malayi Calmodulin-like protein 0.023 0.0397 0.0395
Giardia lamblia Proteasome subunit beta type 1 0.0142 0.0219 0.0608
Brugia malayi carbohydrate phosphorylase 0.0117 0.0169 0.0167
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma cruzi cruzipain precursor, putative 0.0432 0.0803 0.0801
Echinococcus multilocularis EF hand domain containing family member A2 0.0234 0.0405 0.0405
Onchocerca volvulus Cathepsin L homolog 0.1449 0.2852 0.5961
Trichomonas vaginalis calcineurin B subunit, putative 0.0234 0.0405 0.1126
Mycobacterium tuberculosis Conserved protein 0.0443 0.0824 0.2263
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4997 1 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Onchocerca volvulus Cathepsin L homolog 0.0384 0.0706 0.1461
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.009 0.0114 0.0315
Echinococcus granulosus peroxidasin 0.0281 0.0499 0.0499
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0013 0.0013
Onchocerca volvulus 0.0234 0.0405 0.0829
Brugia malayi proteasome subunit alpha type 3 0.004 0.0013 0.0012
Brugia malayi cathepsin L-like cysteine proteinase 0.0384 0.0706 0.0704
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0223 0.0222
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Onchocerca volvulus 0.01 0.0135 0.0263
Trypanosoma cruzi cysteine peptidase, putative 0.1449 0.2852 0.2851
Brugia malayi Eukaryotic aspartyl protease family protein 0.0054 0.0042 0.0041
Echinococcus multilocularis calmodulin 0.023 0.0397 0.0397
Trypanosoma brucei SIR2-like protein 4, putative 0.0066 0.0066 0.0154
Plasmodium vivax aspartyl protease, putative 0.0297 0.0532 0.1861
Brugia malayi histone deacetylase 11 0.0045 0.0023 0.0021
Trypanosoma brucei histone deacetylase 1 0.0093 0.012 0.0281
Trypanosoma cruzi cysteine proteinase, putative 0.0816 0.1576 0.1575
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0421 0.0781 0.078
Echinococcus multilocularis Transglutaminase 0.0443 0.0824 0.0824
Plasmodium vivax hypothetical protein, conserved 0.0299 0.0536 0.1874
Brugia malayi EF hand family protein 0.023 0.0397 0.0395
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Onchocerca volvulus 0.0054 0.0042 0.0069
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trypanosoma brucei I/6 autoantigen 0.023 0.0397 0.0938
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Loa Loa (eye worm) proteasome subunit alpha type 2 0.004 0.0013 0.0012
Plasmodium vivax metacaspase 1, putative 0.014 0.0214 0.0745
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0141 0.0217 0.0217
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.004 0.0013 0.0028
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1449 0.2852 1
Echinococcus granulosus Transglutaminase 0.0443 0.0824 0.0824
Echinococcus multilocularis proteasome subunit alpha type 2 0.004 0.0013 0.0013
Plasmodium falciparum serine repeat antigen 4 0.0384 0.0706 0.2471
Plasmodium falciparum plasmepsin V 0.0054 0.0042 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi centrin-3 0.0238 0.0411 0.041
Trypanosoma brucei metacaspase 0.014 0.0214 0.0504
Echinococcus multilocularis cathepsin L 0.0384 0.0706 0.0706
Trichomonas vaginalis calmodulin-2, putative 0.023 0.0397 0.1104
Brugia malayi Cathepsin L-like precursor 0.1017 0.1982 0.1981
Brugia malayi Kringle domain containing protein 0.007 0.0075 0.0073
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0384 0.0706 0.2471
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0009 0.0008
Schistosoma mansoni centrin-related 0.023 0.0397 0.0397
Plasmodium vivax proteasome subunit beta type-7, putative 0.004 0.0013 0.0041
Brugia malayi prolyl oligopeptidase family protein 0.0299 0.0536 0.0534
Echinococcus multilocularis cathepsin b 0.4997 1 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0299 0.0536 0.1493
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.023 0.0397 0.0397
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.004 0.0013 0.0013
Toxoplasma gondii EFHC1, putative 0.023 0.0397 0.0938
Echinococcus granulosus neuronal calcium sensor 0.023 0.0397 0.0397
Plasmodium vivax proteasome subunit alpha type-3, putative 0.004 0.0013 0.0041
Echinococcus multilocularis Mastin 0.0181 0.0298 0.0298
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0248 0.0432 0.1021
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0099 0.0132 0.013
Mycobacterium tuberculosis Hypothetical protein 0.0443 0.0824 0.2263
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.1062 0.2073 0.2073
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0688 0.1319 0.3128
Echinococcus multilocularis gamma secretase subunit aph 1 0.027 0.0477 0.0477
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0054 0.0042 0.0097
Echinococcus multilocularis subfamily T1A non peptidase ue 0.004 0.0013 0.0013
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Brugia malayi Cathepsin L-like precursor 0.1017 0.1982 0.1981
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.004 0.0013 0.0012
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0688 0.1319 0.1318
Brugia malayi Papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Leishmania major calmodulin, putative 0.023 0.0397 0.0938
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0012 0.5
Toxoplasma gondii cathepsin CPL 0.1449 0.2852 0.6768
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Loa Loa (eye worm) hypothetical protein 0.0299 0.0536 0.0534
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Mycobacterium tuberculosis Probable peptidase 0.0896 0.1739 0.4803
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.004 0.0013 0.0012
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.004 0.0013 0.0041
Echinococcus granulosus integrin alpha ps 0.004 0.0013 0.0013
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0285 0.0508 0.1414
Echinococcus granulosus Mastin 0.0181 0.0298 0.0298
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0896 0.1739 0.1737
Echinococcus granulosus geminin 0.0177 0.0289 0.0289
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Plasmodium vivax plasmepsin IV, putative 0.0054 0.0042 0.0143
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Loa Loa (eye worm) hypothetical protein 0.1449 0.2852 0.2851
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0384 0.0706 0.2471
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Schistosoma mansoni memapsin-2 (A01 family) 0.0532 0.1004 0.1004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0384 0.0706 0.1968
Loa Loa (eye worm) beta-lactamase 0.0038 0.0009 0.0008
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0051 0.0035 0.007
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Leishmania major centrin, putative 0.023 0.0397 0.0938
Mycobacterium ulcerans hypothetical protein 0.0443 0.0824 0.4712
Loa Loa (eye worm) hypothetical protein 0.0191 0.0318 0.0316
Brugia malayi hypothetical protein 0.0277 0.0491 0.049
Giardia lamblia 20S proteasome alpha subunit 6 0.004 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.006 0.0053 0.0051
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0258 0.0452 0.107
Loa Loa (eye worm) calpain D 0.0421 0.0781 0.078
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.004 0.0013 0.0028
Echinococcus multilocularis proteasome subunit alpha type 6 0.004 0.0013 0.0013
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.0013 0.0012
Echinococcus multilocularis GPI anchor transamidase 0.0034 0.0002 0.0002
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Plasmodium vivax vivapain-3 0.0816 0.1576 0.5523
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0397 0.1104
Plasmodium falciparum histone deacetylase, putative 0.0104 0.0143 0.0495
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0093 0.012 0.033
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.004 0.0013 0.0012
Toxoplasma gondii calmodulin CAM1 0.0234 0.0405 0.0957
Entamoeba histolytica hypothetical protein, conserved 0.0299 0.0536 0.1874
Brugia malayi beta-lactamase family protein 0.0038 0.0009 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Plasmodium vivax hypothetical protein, conserved 0.014 0.0214 0.0745
Trypanosoma brucei Component of motile flagella 41 0.023 0.0397 0.0938
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0384 0.0706 0.0706
Plasmodium falciparum plasmepsin IV 0.0054 0.0042 0.0143
Schistosoma mansoni calpain-7 (C02 family) 0.1443 0.284 0.284
Brugia malayi calpain family protein 1 0.3845 0.768 0.7679
Echinococcus granulosus cathepsin l1 0.1017 0.1982 0.1982
Giardia lamblia Thymus-specific serine protease precursor 0.0064 0.0061 0.0166
Plasmodium vivax serine-repeat antigen (SERA) 0.0384 0.0706 0.2471
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Loa Loa (eye worm) hypothetical protein 0.0045 0.0023 0.0021
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.004 0.0013 0.0013
Loa Loa (eye worm) transcriptional regulator 0.0258 0.0452 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Loa Loa (eye worm) calmodulin-like protein 0.023 0.0397 0.0395
Brugia malayi cathepsin F-like cysteine proteinase 0.0384 0.0706 0.0704
Toxoplasma gondii histone deacetylase HDAC1 0.0104 0.0143 0.0335
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.004 0.0013 0.0041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Trypanosoma cruzi histone deacetylase, putative 0.0104 0.0143 0.0141
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0421 0.0781 0.1851
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1825 0.361 1
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Plasmodium falciparum plasmepsin I 0.0054 0.0042 0.0143
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.0488 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Trypanosoma brucei centrin, putative 0.023 0.0397 0.0938
Schistosoma mansoni calpain C (C02 family) 0.144 0.2834 0.2834
Giardia lamblia Transglutaminase/protease, putative 0.0443 0.0824 0.2299
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0223 0.0223
Loa Loa (eye worm) proteasome subunit alpha type 3 0.004 0.0013 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Plasmodium falciparum cysteine proteinase falcipain 3 0.1449 0.2852 1
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Plasmodium vivax histone deacetylase, putative 0.0104 0.0143 0.0495
Plasmodium falciparum proteasome subunit beta type-5 0.0248 0.0432 0.1509
Loa Loa (eye worm) hypothetical protein 0.0219 0.0374 0.0372
Toxoplasma gondii aspartyl protease ASP3 0.0297 0.0532 0.1259
Loa Loa (eye worm) hypothetical protein 0.1017 0.1982 0.1981
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0142 0.0219 0.0516
Plasmodium falciparum peptidase, putative 0.0299 0.0536 0.1874
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.004 0.0013 0.0013
Leishmania major centrin, putative 0.023 0.0397 0.0938
Echinococcus multilocularis histone deacetylase 7 0.0104 0.0143 0.0143
Plasmodium vivax NAD-dependent deacetylase, putative 0.0066 0.0066 0.0227
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0135 0.0135
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Plasmodium falciparum cysteine proteinase falcipain 1 0.0816 0.1576 0.5523
Brugia malayi Angiotensin-converting enzyme family protein 0.1829 0.3619 0.3618
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0143 0.0143
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0384 0.0706 0.1968
Toxoplasma gondii heat shock protein hslv, putative 0.004 0.0013 0.0028
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0057 0.0049 0.0047
Entamoeba histolytica prolyl oligopeptidase family protein 0.0299 0.0536 0.1874
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Schistosoma mansoni aldehyde dehydrogenase 0.0141 0.0217 0.0217
Schistosoma mansoni centrin 0.023 0.0397 0.0397
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Entamoeba histolytica prolyl oligopeptidase family protein 0.0299 0.0536 0.1874
Brugia malayi hypothetical protein 0.0181 0.0298 0.0296
Echinococcus granulosus integrin alpha 3 0.0142 0.0218 0.0218
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0066 0.0066 0.0227
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0223 0.0222
Toxoplasma gondii proteasome beta subunit 0.004 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trichomonas vaginalis hypothetical protein 0.0421 0.0781 0.2178
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0054 0.0042 0.0042
Onchocerca volvulus 0.0181 0.0298 0.0605
Brugia malayi Cell death protein 3 precursor 0.0322 0.0581 0.058
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Echinococcus multilocularis histone deacetylase 1 0.0093 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0012 0.003
Trichomonas vaginalis conserved hypothetical protein 0.023 0.0397 0.1104
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Plasmodium vivax unspecified product 0.0816 0.1576 0.5523
Trypanosoma cruzi calmodulin, putative 0.023 0.0397 0.0395
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.1185 0.2319 0.2319
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0054 0.0042 0.0041
Schistosoma mansoni histone deacetylase 1 2 3 0.0045 0.0023 0.0023
Echinococcus multilocularis histone deacetylase 6 0.0111 0.0156 0.0156
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.004 0.0013 0.0013
Brugia malayi MH2 domain containing protein 0.0133 0.02 0.0198
Trypanosoma brucei proteasome beta 7 subunit 0.004 0.0013 0.0028
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Leishmania major hypothetical protein, conserved 0.0421 0.0781 0.1851
Plasmodium vivax calpain, putative 0.144 0.2834 0.9935
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Onchocerca volvulus 0.0792 0.1528 0.3185
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0142 0.0219 0.0219
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.004 0.0013 0.0041
Schistosoma mansoni integrin alpha-ps 0.0043 0.002 0.002
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0035 0.0116
Echinococcus granulosus glycoprotein Antigen 5 0.0181 0.0298 0.0298
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Plasmodium vivax hypothetical protein, conserved 0.0234 0.0405 0.1414
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Trypanosoma brucei calpain, putative 0.0421 0.0781 0.1851
Trypanosoma brucei histone deacetylase 2 0.0045 0.0023 0.0051
Giardia lamblia Cathepsin L-like protease 0.0384 0.0706 0.1968
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Echinococcus granulosus calumenin 0.0234 0.0405 0.0405
Plasmodium vivax histone deacetylase 1, putative 0.0093 0.012 0.0415
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4997 1 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0033 0.0033
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Loa Loa (eye worm) integrin beta-2 0.0378 0.0695 0.0693
Loa Loa (eye worm) proteasome subunit beta type 2 0.009 0.0114 0.0113
Echinococcus granulosus glycogen phosphorylase 0.0117 0.0169 0.0169
Brugia malayi proteasome subunit alpha type 2 0.004 0.0013 0.0012
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0248 0.0432 0.043
Trypanosoma brucei metacaspase MCA3 0.014 0.0214 0.0504
Trichomonas vaginalis glycogen phosphorylase, putative 0.0117 0.0169 0.0466
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0181 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0066 0.0066 0.0064
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.004 0.0013 0.0013
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.023 0.0397 0.0938
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.181 0.358 1
Leishmania major proteasome beta 5 subunit, putative 0.0248 0.0432 0.1021
Toxoplasma gondii proteasome subunit beta type, putative 0.0248 0.0432 0.1021
Brugia malayi calpain 5 0.0421 0.0781 0.078
Leishmania major proteasome beta 3 subunit, putative 0.004 0.0013 0.0028
Plasmodium falciparum proteasome subunit beta type-4 0.004 0.0013 0.0041
Schistosoma mansoni cathepsin B (C01 family) 0.0384 0.0706 0.0706
Loa Loa (eye worm) calpain 0.144 0.2834 0.2833
Onchocerca volvulus 0.1449 0.2852 0.5961
Loa Loa (eye worm) hypothetical protein 0.004 0.0013 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0384 0.0706 0.1968
Plasmodium falciparum serine repeat antigen 9 0.0384 0.0706 0.2471
Loa Loa (eye worm) histone deacetylase 1 0.0093 0.012 0.0118
Schistosoma mansoni hypothetical protein 0.0177 0.0289 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0248 0.0432 0.043
Brugia malayi proteasome subunit beta type 2 0.009 0.0114 0.0113
Brugia malayi transcriptional regulator, Sir2 family protein 0.0066 0.0066 0.0065
Echinococcus multilocularis inhibitor of apoptosis protein 0.0191 0.0318 0.0318
Toxoplasma gondii cathepsin CPC1 0.0384 0.0706 0.1672
Entamoeba histolytica cysteine proteinase, putative 0.0816 0.1576 0.5523
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.1829 0.3619 0.3618
Onchocerca volvulus Cathepsin L homolog 0.1449 0.2852 0.5961
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.009 0.0114 0.0114
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma cruzi cysteine peptidase, putative 0.0432 0.0803 0.0801
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.004 0.0013 0.0041
Onchocerca volvulus 0.1449 0.2852 0.5961
Loa Loa (eye worm) hypothetical protein 0.023 0.0397 0.0395
Brugia malayi cathepsin L-like precursor 0.1017 0.1982 0.1981
Onchocerca volvulus 0.0178 0.0292 0.0593
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.004 0.0013 0.0028
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.004 0.0013 0.0012
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0066 0.0066 0.0066
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.004 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Mycobacterium ulcerans zinc metalloprotease 0.0099 0.0132 0.0709
Trypanosoma brucei prolyl endopeptidase 0.2125 0.4213 1
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Trypanosoma cruzi Aph-1 protein, putative 0.0105 0.0145 0.0143
Echinococcus granulosus centrin 2 0.023 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0181 0.0298 0.0298
Echinococcus granulosus cathepsin l1 0.1449 0.2852 0.2852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Plasmodium vivax proteasome subunit beta type-4, putative 0.004 0.0013 0.0041
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0432 0.0803 0.0801
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0012 0.0011
Toxoplasma gondii EF hand domain-containing protein 0.023 0.0397 0.0938
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Onchocerca volvulus 0.0615 0.1172 0.2438
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Echinococcus granulosus histone lysine methyltransferase setb 0.01 0.0135 0.0135
Trypanosoma cruzi histone deacetylase, putative 0.0104 0.0143 0.0141
Trichomonas vaginalis peptide N-glycanase, putative 0.0443 0.0824 0.2299
Brugia malayi aspartic protease BmAsp-1, identical 0.0054 0.0042 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Loa Loa (eye worm) hypothetical protein 0.2125 0.4213 0.4212
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.1851
Leishmania major calpain protease-like protein 0.0421 0.0781 0.1851
Echinococcus multilocularis integrin alpha 3 0.0142 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0145 0.0225 0.0223
Schistosoma mansoni chromatin regulatory protein sir2 0.0066 0.0066 0.0066
Echinococcus multilocularis programmed cell death protein 0.0238 0.0411 0.0411
Trypanosoma brucei ATP-dependent protease subunit HslV 0.004 0.0013 0.0028
Giardia lamblia Histone deacetylase 0.0093 0.012 0.033
Brugia malayi beta-lactamase family protein 0.0038 0.0009 0.0008
Plasmodium falciparum centrin-1 0.023 0.0397 0.1386
Loa Loa (eye worm) hypothetical protein 0.0102 0.0138 0.0136
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.1062 0.2073 0.2073
Brugia malayi calpain 7 0.144 0.2834 0.2833
Echinococcus multilocularis hypothetical protein 0.144 0.2834 0.2834
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.004 0.0013 0.0028
Toxoplasma gondii troponin c, isotype gamma, putative 0.023 0.0397 0.0938
Echinococcus granulosus subfamily T1A non peptidase ue 0.004 0.0013 0.0013
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Toxoplasma gondii subtilisin SUB12 0.0046 0.0025 0.0054
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0054 0.0042 0.0041
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1073 0.2094 0.2093
Loa Loa (eye worm) hypothetical protein 0.014 0.0214 0.0212
Plasmodium vivax cysteine repeat modular protein 1, putative 0.007 0.0075 0.0256
Giardia lamblia 20S proteasome alpha subunit 4 0.004 0.0013 0.0033
Brugia malayi ERG2 and Sigma1 receptor like protein 0.037 0.0678 0.0676
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.004 0.0013 0.0041
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0012 0.0011
Brugia malayi Thioredoxin family protein 0.0443 0.0824 0.0823
Echinococcus granulosus histone deacetylase 8 0.0045 0.0023 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0009 0.0018
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.0013 0.0012
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0248 0.0432 0.1509
Echinococcus multilocularis histone deacetylase 8 0.0045 0.0023 0.0023
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.023 0.0397 0.0395
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0214 0.0504
Onchocerca volvulus 0.0046 0.0025 0.0032
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0064 0.0061 0.0166
Mycobacterium ulcerans aldehyde dehydrogenase 0.0141 0.0217 0.1198
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0099 0.0132 0.013
Echinococcus granulosus histone deacetylase 3 0.0093 0.012 0.012
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Echinococcus granulosus sarcoplasmic calcium binding protein 0.023 0.0397 0.0397
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0384 0.0706 0.0706
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Echinococcus granulosus calpain 0.144 0.2834 0.2834
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0896 0.1739 0.4125
Leishmania major phospholipase c-like protein 0.023 0.0397 0.0938
Brugia malayi aspartic protease BmAsp-2, identical 0.0054 0.0042 0.0041
Echinococcus granulosus histone deacetylase 7 0.0104 0.0143 0.0143
Schistosoma mansoni glycogen phosphorylase 0.0117 0.0169 0.0169
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0384 0.0706 0.2471
Leishmania major proteasome alpha 1 subunit, putative 0.004 0.0013 0.0028
Onchocerca volvulus Cell death protein 3 homolog 0.0322 0.0581 0.1199
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0054 0.0042 0.0114
Plasmodium falciparum serine repeat antigen 6 0.0384 0.0706 0.2471
Schistosoma mansoni cathepsin C 0.0384 0.0706 0.0706
Brugia malayi Animal haem peroxidase family protein 0.0281 0.0499 0.0497
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0099 0.0132 0.0132
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Trypanosoma cruzi kinesin, putative 0.1019 0.1985 0.1984
Toxoplasma gondii centrin 0.023 0.0397 0.0938
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0299 0.0536 0.1874
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Entamoeba histolytica grainin 2 0.0238 0.0411 0.1438
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0214 0.0504
Giardia lamblia Proteasome subunit beta type 7 precursor 0.004 0.0013 0.0033
Onchocerca volvulus Chorion peroxidase homolog 0.0281 0.0499 0.1026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Toxoplasma gondii preprocathepsin c precursor, putative 0.0384 0.0706 0.1672
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Echinococcus multilocularis cysteine protease 0.1449 0.2852 0.2852
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0191 0.0318 0.0318
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0066 0.0066 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Trypanosoma cruzi oligopeptidase b 0.0896 0.1739 0.1737
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Echinococcus multilocularis integrin alpha ps 0.0083 0.01 0.01
Schistosoma mansoni inhibitor of apoptosis protein 0.0191 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.023 0.0397 0.1104
Echinococcus multilocularis caspase 3 0.0286 0.0509 0.0509
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0142 0.0219 0.0217
Brugia malayi hypothetical protein 0.0054 0.0042 0.0041
Brugia malayi Histone deacetylase 1 0.0093 0.012 0.0118
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0816 0.1576 0.1576
Trypanosoma cruzi caltractin, putative 0.023 0.0397 0.0395
Echinococcus multilocularis apoptotic protease activating factor 1 0.0182 0.03 0.03
Mycobacterium ulcerans putative transglutaminase-like protein 0.0443 0.0824 0.4712
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0142 0.0219 0.0763
Echinococcus multilocularis tumor protein p63 0.0399 0.0736 0.0736
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Schistosoma mansoni cathepsin F (C01 family) 0.1017 0.1982 0.1982
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.1062 0.2073 0.2073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0096 0.0126 0.0126
Echinococcus multilocularis neuronal calcium sensor 0.023 0.0397 0.0397
Brugia malayi proteasome subunit beta type 1 0.0142 0.0219 0.0217
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.004 0.0013 0.0012
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.014 0.0214 0.0504
Trypanosoma brucei Calpain-like protein 1.1 0.0421 0.0781 0.1851
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0066 0.0066 0.0154
Entamoeba histolytica calcium binding family protein 0.023 0.0397 0.1386
Onchocerca volvulus Deterin homolog 0.0191 0.0318 0.0647
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.004 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, putative 0.0421 0.0781 0.1851
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.005 0.0033 0.0033
Trypanosoma cruzi cysteine protease, putative 0.0816 0.1576 0.1575
Giardia lamblia 20S proteasome alpha subunit 7 0.004 0.0013 0.0033
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.005 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0058 0.005 0.0049
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Echinococcus multilocularis proteasome (prosome, macropain) 0.0248 0.0432 0.0432
Mycobacterium ulcerans Sir2-like regulatory protein 0.0066 0.0066 0.0329
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.004 0.0013 0.0041
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0012 0.0011
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.004 0.0013 0.0013
Giardia lamblia Hypothetical protein 0.0443 0.0824 0.2299
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.023 0.0397 0.0395
Loa Loa (eye worm) integrin alpha pat-2 0.0285 0.0506 0.0505
Loa Loa (eye worm) prolyl oligopeptidase 0.0299 0.0536 0.0534
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Echinococcus multilocularis histone deacetylase 0.0104 0.0143 0.0143
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Toxoplasma gondii PAN/Apple domain-containing protein 0.0046 0.0025 0.0054
Trypanosoma cruzi major cysteine proteinase, putative 0.0384 0.0706 0.0704
Onchocerca volvulus 0.1449 0.2852 0.5961
Trypanosoma brucei histone deacetylase 4 0.0104 0.0143 0.0335
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Brugia malayi Pre-SET motif family protein 0.0696 0.1334 0.1333
Brugia malayi hypothetical protein 0.0182 0.03 0.0298
Toxoplasma gondii cathepsin B 0.181 0.358 0.8497
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Schistosoma mansoni hypothetical protein 0.0191 0.0318 0.0318
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0896 0.1739 0.4803
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.181 0.358 0.3579
Loa Loa (eye worm) trypsin family protein 0.0181 0.0298 0.0296
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0066 0.0066 0.0158
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0064 0.0061 0.0059
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.0013 0.0012
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Brugia malayi Papain family cysteine protease containing protein 0.0384 0.0706 0.0704
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0135 0.0135
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.1185 0.2319 0.2319
Mycobacterium tuberculosis Conserved hypothetical protein 0.0443 0.0824 0.2263
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0142 0.0219 0.0763
Schistosoma mansoni cathepsin D (A01 family) 0.0338 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.4997 1 1
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0258 0.0452 0.0451
Schistosoma mansoni glycogen phosphorylase 0.0051 0.0035 0.0035
Plasmodium falciparum proteasome subunit beta type-3, putative 0.004 0.0013 0.0041
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0075 0.0073
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.004 0.0013 0.0012
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.2833
Toxoplasma gondii hypothetical protein 0.0046 0.0025 0.0054
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0384 0.0706 0.1968
Schistosoma mansoni ap endonuclease 0.004 0.0012 0.0012
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0432 0.0803 0.0801
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0142 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.014 0.0214 0.0213
Brugia malayi cathepsin L precursor 0.0384 0.0706 0.0704
Onchocerca volvulus 0.0056 0.0046 0.0077
Schistosoma mansoni hypothetical protein 0.0113 0.0161 0.0161
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.004 0.0013 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0223 0.0223
Toxoplasma gondii hypothetical protein 0.0046 0.0025 0.0054
Onchocerca volvulus 0.1449 0.2852 0.5961
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Loa Loa (eye worm) histone deacetylase 7A 0.0104 0.0143 0.0141
Chlamydia trachomatis glycogen phosphorylase 0.0117 0.0169 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0384 0.0706 0.1968
Echinococcus granulosus GPI anchor transamidase 0.0034 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.01 0.0135 0.0135
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.004 0.0013 0.0033
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.023 0.023
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0142 0.0219 0.0219
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.014 0.0214 0.0593
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.144 0.2834 0.6725
Brugia malayi transcriptional regulator, Sir2 family protein 0.0258 0.0452 0.0451
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0248 0.0432 0.2443
Brugia malayi transcriptional regulator, Sir2 family protein 0.0066 0.0066 0.0065
Echinococcus granulosus caspase 2 0.0322 0.0581 0.0581
Trypanosoma brucei oligopeptidase b 0.0896 0.1739 0.4125
Loa Loa (eye worm) hypothetical protein 0.0181 0.0298 0.0296
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Echinococcus granulosus Proteasome subunit alpha beta 0.004 0.0013 0.0013
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0181 0.0298 0.0296
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0384 0.0706 0.2471
Echinococcus multilocularis calpain family protein 1, d 0.2826 0.5627 0.5627
Entamoeba histolytica protein kinase, putative 0.1019 0.1985 0.6959
Plasmodium vivax proteasome subunit alpha type-1, putative 0.004 0.0013 0.0041
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0299 0.0536 0.1268
Leishmania major hypothetical protein, unknown function 0.0421 0.0781 0.1851
Plasmodium vivax proteasome subunit alpha type-7, putative 0.004 0.0013 0.0041
Loa Loa (eye worm) hypothetical protein 0.023 0.0397 0.0395
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.004 0.0013 0.0028
Echinococcus granulosus EF HAND 1 calcium binding site 0.023 0.0397 0.0397
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Trichomonas vaginalis myosin light chain 1, putative 0.023 0.0397 0.1104
Brugia malayi Proteasome subunit alpha type 7-1 0.004 0.0013 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0041
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0066 0.0066 0.0227
Onchocerca volvulus 0.0046 0.0025 0.0032
Echinococcus multilocularis Glycosyl transferase, family 35 0.0117 0.0169 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0816 0.1576 0.4399
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0041
Giardia lamblia Hypothetical protein 0.0234 0.0405 0.1126
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0046 0.0025 0.0054
Brugia malayi hypothetical protein 0.0281 0.0499 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0061 0.0166
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Trichomonas vaginalis calcium binding proteins, putative 0.023 0.0397 0.1104
Echinococcus granulosus endothelin converting enzyme 1 0.0099 0.0132 0.0132
Onchocerca volvulus Dual oxidase homolog 0.0281 0.0499 0.1026
Trypanosoma brucei cysteine peptidase C (CPC) 0.181 0.358 0.8497
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.004 0.0013 0.0028
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4997 1 1
Toxoplasma gondii hypothetical protein 0.0299 0.0536 0.1268
Mycobacterium ulcerans hypothetical protein 0.0443 0.0824 0.4712
Plasmodium vivax histone deacetylase 2, putative 0.0104 0.0143 0.0495
Loa Loa (eye worm) PAN domain-containing protein 0.0046 0.0025 0.0023
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0896 0.1739 0.4125
Schistosoma mansoni calpain-2 (C02 family) 0.0421 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0189 0.0313 0.0312
Mycobacterium ulcerans NAD-dependent deacetylase 0.0066 0.0066 0.0329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Loa Loa (eye worm) histone deacetylase 3 0.0093 0.012 0.0118
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.027 0.0477 0.0476
Plasmodium falciparum plasmepsin X 0.0297 0.0532 0.1861
Trypanosoma brucei caltractin, putative 0.0238 0.0411 0.0973
Schistosoma mansoni caspase-7 (C14 family) 0.0322 0.0581 0.0581
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0688 0.1319 0.1318
Loa Loa (eye worm) MH2 domain-containing protein 0.0133 0.02 0.0198
Trypanosoma brucei proteasome beta 2 subunit, putative 0.004 0.0013 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0009 0.0008
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Plasmodium falciparum plasmepsin VII 0.0054 0.0042 0.0143
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0816 0.1576 0.1575
Brugia malayi Trypsin family protein 0.0181 0.0298 0.0296
Brugia malayi gamma-secretase subunit aph-1 0.027 0.0477 0.0476
Echinococcus multilocularis dnaJ subfamily B 0.045 0.0839 0.0839
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1449 0.2852 0.2852
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0384 0.0706 0.2471
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.004 0.0013 0.0013
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Onchocerca volvulus Glycogen phosphorylase homolog 0.0117 0.0169 0.0334
Echinococcus multilocularis caspase 8 0.014 0.0214 0.0214
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0285 0.0508 0.1414
Schistosoma mansoni calmodulin related calcium binding protein 0.023 0.0397 0.0397
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0099 0.0132 0.0341
Echinococcus granulosus inhibitor of apoptosis protein 0.0191 0.0318 0.0318
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Brugia malayi Integrin alpha cytoplasmic region family protein 0.014 0.0214 0.0213
Giardia lamblia 20S proteasome alpha subunit 5 0.004 0.0013 0.0033
Plasmodium falciparum plasmepsin VI 0.0054 0.0042 0.0143
Schistosoma mansoni microtubule-associated protein tau 0.0796 0.1536 0.1536
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Brugia malayi Serine carboxypeptidase S28 family protein 0.0064 0.0061 0.0059
Leishmania major histone deacetylase, putative 0.0104 0.0143 0.0335
Onchocerca volvulus 0.0049 0.0031 0.0046
Leishmania major calcineurin B subunit, putative 0.023 0.0397 0.0938
Plasmodium vivax aspartyl proteinase, putative 0.0054 0.0042 0.0143
Trypanosoma cruzi cysteine peptidase, putative 0.0816 0.1576 0.1575
Schistosoma mansoni mitochondrial solute carrier 0.023 0.0397 0.0397
Brugia malayi Kelch motif family protein 0.0057 0.0049 0.0047
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.023 0.0397 0.0397
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0816 0.1576 0.1575
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Loa Loa (eye worm) animal heme peroxidase 0.0281 0.0499 0.0497
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0066 0.0066 0.0066
Plasmodium falciparum serine repeat antigen 3 0.0384 0.0706 0.2471
Plasmodium vivax aspartyl protease, putative 0.0054 0.0042 0.0143
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0264 0.0465 0.1627
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.144 0.2834 0.6725
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.004 0.0013 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trypanosoma brucei proteasome alpha 7 subunit 0.004 0.0013 0.0028
Echinococcus granulosus calmodulin 0.023 0.0397 0.0397
Toxoplasma gondii kringle domain-containing protein 0.007 0.0075 0.0174
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.004 0.0013 0.0028
Echinococcus granulosus cathepsin b 0.4997 1 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0384 0.0706 0.2471
Toxoplasma gondii proteasome subunit beta type 2, putative 0.009 0.0114 0.0267
Echinococcus granulosus glycogen phosphorylase 0.0117 0.0169 0.0169
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0191 0.0318 0.0316
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0141 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.1017 0.1982 0.1981
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0384 0.0706 0.2471
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0147 0.023 0.023
Plasmodium falciparum serine repeat antigen 7 0.0384 0.0706 0.2471
Schistosoma mansoni cathepsin F (C01 family) 0.1449 0.2852 0.2852
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.004 0.0013 0.0012
Giardia lamblia Cathepsin L precursor 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.004 0.0013 0.0041
Toxoplasma gondii microneme protein, putative 0.0046 0.0025 0.0054
Onchocerca volvulus 0.0046 0.0025 0.0032
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.004 0.0013 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Leishmania major oligopeptidase b 0.0896 0.1739 0.4125
Echinococcus granulosus caspase 3 0.0286 0.0509 0.0509
Echinococcus multilocularis proteasome subunit beta type 6 0.004 0.0013 0.0013
Entamoeba histolytica calcium-binding protein, putative 0.023 0.0397 0.1386
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.181 0.358 0.358
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1017 0.1982 0.5534
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0141 0.0217 0.0575
Loa Loa (eye worm) hypothetical protein 0.2405 0.4778 0.4778
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0012 0.0017
Echinococcus multilocularis transmembrane protease serine 3 0.0181 0.0298 0.0298
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0258 0.0452 0.1259
Echinococcus multilocularis histone deacetylase 6 0.0104 0.0143 0.0143
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0397 0.1104
Loa Loa (eye worm) transcriptional regulator 0.0066 0.0066 0.0065
Onchocerca volvulus 0.0046 0.0025 0.0032
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.004 0.0013 0.0028
Leishmania major cathepsin L-like protease 0.1449 0.2852 0.6768
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.004 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Plasmodium falciparum metacaspase 1 0.014 0.0214 0.0745
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.004 0.0013 0.0013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.144 0.2834 0.2833
Brugia malayi fibroinase precursor 0.0384 0.0706 0.0704
Toxoplasma gondii histone deacetylase HDAC2 0.0093 0.012 0.0281
Loa Loa (eye worm) peptidase C13 family protein 0.0147 0.023 0.0228
Loa Loa (eye worm) hypothetical protein 0.0073 0.008 0.0078
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.004 0.0013 0.0012
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.004 0.0013 0.0041
Echinococcus granulosus proteasome subunit alpha type 6 0.004 0.0013 0.0013
Trypanosoma cruzi centrin, putative 0.0238 0.0411 0.041
Brugia malayi proteasome subunit alpha type 4 0.004 0.0013 0.0012
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Entamoeba histolytica cysteine protease, putative 0.1449 0.2852 1
Echinococcus granulosus proteasome subunit alpha type 2 0.004 0.0013 0.0013
Trypanosoma cruzi 20S proteasome subunit 0.009 0.0114 0.0113
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0421 0.0781 0.078
Schistosoma mansoni hypothetical protein 0.0056 0.0046 0.0046
Plasmodium falciparum cysteine repeat modular protein 1 0.007 0.0075 0.0256
Mycobacterium leprae probable zinc metalloprotease 0.0099 0.0132 0.0709
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.004 0.0013 0.0013
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0384 0.0706 0.2471
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0066 0.0066 0.0066
Loa Loa (eye worm) cysteine protease 0.1449 0.2852 0.2851
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Loa Loa (eye worm) hypothetical protein 0.0411 0.0761 0.0759
Entamoeba histolytica proteasome subunit beta type 3, putative 0.004 0.0013 0.0041
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0034 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0223 0.0223
Leishmania major cathepsin L-like protease 0.1505 0.2964 0.7034
Echinococcus granulosus histone deacetylase 0.0104 0.0143 0.0143
Echinococcus granulosus transmembrane protease serine 3 0.0181 0.0298 0.0298
Brugia malayi Peptidase family M13 containing protein 0.0099 0.0132 0.013
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0299 0.0536 0.0534
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0181 0.0298 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Giardia lamblia 20S proteasome alpha subunit 1 0.004 0.0013 0.0033
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0064 0.0061 0.0166
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0064 0.0061 0.0141
Brugia malayi Papain family cysteine protease containing protein 0.1449 0.2852 0.2851
Loa Loa (eye worm) calpain 5 0.1019 0.1985 0.1984
Mycobacterium leprae Conserved hypothetical protein 0.0443 0.0824 0.4712
Entamoeba histolytica cysteine proteinase, putative 0.1449 0.2852 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0384 0.0706 0.1968
Plasmodium falciparum serine repeat antigen 5 0.0384 0.0706 0.2471
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.023 0.0397 0.0395
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0896 0.1739 0.1737
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0384 0.0706 0.1968
Schistosoma mansoni neuronal calcium sensor 0.023 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0075 0.0083 0.0082
Toxoplasma gondii centrin, putative 0.023 0.0397 0.0938
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0064 0.0061 0.0061
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.004 0.0013 0.0023
Toxoplasma gondii exonuclease III APE 0.004 0.0012 0.0025
Loa Loa (eye worm) calpain family protein 1 0.2826 0.5627 0.5626
Loa Loa (eye worm) hypothetical protein 0.0057 0.0049 0.0047
Plasmodium falciparum serine repeat antigen 8 0.0384 0.0706 0.2471
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.0422 0.1147
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0384 0.0706 0.0706
Echinococcus granulosus gamma secretase subunit aph 1 0.027 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0009 0.0022
Trypanosoma cruzi histone deacetylase, putative 0.0104 0.0143 0.0141
Leishmania major calmodulin, putative 0.023 0.0397 0.0938
Plasmodium vivax centrin-1, putative 0.023 0.0397 0.1386
Onchocerca volvulus 0.007 0.0075 0.0137
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.0488 0.0488
Echinococcus granulosus Glycosyl transferase family 35 0.0117 0.0169 0.0169
Schistosoma mansoni calmodulin 0.023 0.0397 0.0397
Entamoeba histolytica grainin, putative 0.0234 0.0405 0.1414
Schistosoma mansoni ap endonuclease 0.004 0.0012 0.0012
Echinococcus granulosus apoptotic protease activating factor 1 0.0182 0.03 0.03
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0223 0.0223
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0147 0.023 0.0637
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Echinococcus multilocularis microtubule associated protein 2 0.0796 0.1536 0.1536
Plasmodium vivax proteasome subunit alpha type-4, putative 0.004 0.0013 0.0041
Echinococcus multilocularis centrin 2 0.023 0.0397 0.0397
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0064 0.0061 0.0061
Brugia malayi prolyl oligopeptidase family protein 0.0299 0.0536 0.0534
Toxoplasma gondii ABC1 family protein 0.0038 0.0009 0.0018
Entamoeba histolytica glycogen phosphorylase, putative 0.0051 0.0035 0.0116
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.004 0.0013 0.0041
Trichomonas vaginalis calpain, putative 0.0421 0.0781 0.2178
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Echinococcus granulosus cathepsin L cysteine proteinase 0.1449 0.2852 0.2852
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0142 0.0219 0.0608
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0384 0.0706 0.1968
Schistosoma mansoni hypothetical protein 0.023 0.0397 0.0397
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4997 1 1
Echinococcus multilocularis caspase 0.0426 0.0791 0.0791
Echinococcus multilocularis glycogen phosphorylase 0.0117 0.0169 0.0169
Leishmania major C-8 sterol isomerase-like protein 0.037 0.0678 0.1605
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Trypanosoma cruzi metacaspase 5, putative 0.014 0.0214 0.0212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Trypanosoma cruzi I/6 autoantigen, putative 0.023 0.0397 0.0395
Trypanosoma brucei antigen, putative 0.144 0.2834 0.6725
Plasmodium vivax proteasome subunit beta type-2, putative 0.009 0.0114 0.0395
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0816 0.1576 0.3738
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0896 0.1739 1
Mycobacterium ulcerans hypothetical protein 0.0181 0.0298 0.1668
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0421 0.0781 0.1851
Schistosoma mansoni integrin alpha-ps 0.0083 0.01 0.01
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0421 0.0781 0.078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.004 0.0013 0.0041
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0285 0.0508 0.0508
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.004 0.0013 0.0028
Toxoplasma gondii histone deacetylase HDAC5 0.0045 0.0023 0.0052
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0012 0.0037
Schistosoma mansoni hypothetical protein 0.004 0.0013 0.0013
Echinococcus multilocularis integrin beta 2 0.028 0.0497 0.0497
Trichomonas vaginalis calcium binding protein, putative 0.023 0.0397 0.1104
Plasmodium vivax proteasome subunit beta type-6, putative 0.004 0.0013 0.0041
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0816 0.1576 0.1576
Echinococcus multilocularis proteasome subunit beta type 7 0.004 0.0013 0.0013
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0054 0.0042 0.0097
Schistosoma mansoni reticulocalbin 0.023 0.0397 0.0397
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0384 0.0706 0.2471
Giardia lamblia Cysteine protease 0.0384 0.0706 0.1968
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.023 0.0397 0.1104
Brugia malayi prolyl oligopeptidase family protein 0.2125 0.4213 0.4212
Brugia malayi Serine protease Z688.6 precursor 0.0064 0.0061 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1449 0.2852 0.7966
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0426 0.0791 0.0791
Trypanosoma cruzi calmodulin, putative 0.023 0.0397 0.0395
Brugia malayi prolyl oligopeptidase family protein 0.1062 0.2073 0.2071
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0066 0.0066 0.0181
Echinococcus granulosus dnaJ subfamily B 0.045 0.0839 0.0839
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Entamoeba histolytica cysteine proteinase 2 0.0816 0.1576 0.5523
Plasmodium vivax histone deacetylase, putative 0.0045 0.0023 0.0075
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.004 0.0013 0.0012
Leishmania major histone deacetylase, putative 0.0104 0.0143 0.0335
Giardia lamblia Cathepsin B precursor 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.0178 0.0292 0.029
Loa Loa (eye worm) transcriptional regulator 0.0066 0.0066 0.0065
Schistosoma mansoni cathepsin F (C01 family) 0.1449 0.2852 0.2852
Entamoeba histolytica cysteine proteinase, putative 0.1017 0.1982 0.6948
Leishmania major proteasome beta 2 subunit, putative 0.009 0.0114 0.0267
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Echinococcus granulosus cathepsin L 0.0384 0.0706 0.0706
Trypanosoma cruzi C-8 sterol isomerase, putative 0.037 0.0678 0.0676
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Brugia malayi cathepsin Z-like cysteine proteinase 0.0384 0.0706 0.0704
Loa Loa (eye worm) histone deacetylase 0.0104 0.0143 0.0141
Onchocerca volvulus 0.023 0.0397 0.0812
Brugia malayi calpain family protein 1 0.3845 0.768 0.7679
Plasmodium vivax proteasome subunit alpha type-6, putative 0.004 0.0013 0.0041
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Schistosoma mansoni chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Toxoplasma gondii microneme protein MIC17C 0.0046 0.0025 0.0054
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0421 0.0781 0.078
Trypanosoma cruzi cysteine peptidase, putative 0.1505 0.2964 0.2963
Giardia lamblia Cathepsin B precursor 0.181 0.358 1
Loa Loa (eye worm) EF hand family protein 0.023 0.0397 0.0395
Echinococcus multilocularis integrin alpha ps 0.0083 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0046 0.0025 0.0023
Schistosoma mansoni chromatin regulatory protein sir2 0.0258 0.0452 0.0452
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.004 0.0013 0.0012
Trichomonas vaginalis calcineurin B subunit, putative 0.023 0.0397 0.1104
Entamoeba histolytica calmodulin, putative 0.023 0.0397 0.1386
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0075 0.0075
Echinococcus granulosus tumor protein p63 0.0399 0.0736 0.0736
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0248 0.0432 0.0432
Brugia malayi Integrin beta pat-3 precursor 0.0378 0.0695 0.0693
Echinococcus granulosus EF hand domain containing family member A2 0.0234 0.0405 0.0405
Brugia malayi Blistered cuticle protein 3 0.0281 0.0499 0.0497
Echinococcus multilocularis neurocalcin 0.023 0.0397 0.0397
Trichomonas vaginalis calmodulin, putative 0.023 0.0397 0.1104
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0064 0.0061 0.0166
Toxoplasma gondii peptidase, T1 family protein 0.004 0.0013 0.0028
Onchocerca volvulus 0.0191 0.0318 0.0647
Giardia lamblia Alanyl dipeptidyl peptidase 0.0299 0.0536 0.1493
Brugia malayi Trypsin-like protease protein 5 0.0181 0.0298 0.0296
Leishmania major calmodulin-like protein 0.023 0.0397 0.0938
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0421 0.0781 0.2178
Loa Loa (eye worm) hypothetical protein 0.0099 0.0132 0.013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Brugia malayi proteasome subunit beta type 3 0.004 0.0013 0.0012
Leishmania major proteasome beta 7 subunit, putative 0.004 0.0013 0.0028
Onchocerca volvulus 0.0054 0.0042 0.0069
Mycobacterium ulcerans proteasome PrcB 0.0248 0.0432 0.2443
Loa Loa (eye worm) hypothetical protein 0.3424 0.6831 0.6831
Schistosoma mansoni histone deacetylase 0.0093 0.012 0.012
Mycobacterium ulcerans proteasome PrcA 0.004 0.0013 0.0023
Entamoeba histolytica calmodulin, putative 0.023 0.0397 0.1386
Giardia lamblia Transcriptional regulator, Sir2 family 0.0066 0.0066 0.0181
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.01 0.0135 0.0135
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0064 0.0061 0.0061
Leishmania major metacaspase, putative 0.014 0.0214 0.0504
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.009 0.0114 0.0114
Toxoplasma gondii aldehyde dehydrogenase 0.0141 0.0217 0.051
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Toxoplasma gondii microneme protein MIC17B 0.0046 0.0025 0.0054
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0022
Trypanosoma cruzi cysteine peptidase, putative 0.1505 0.2964 0.2963
Leishmania major hypothetical protein, conserved 0.0038 0.0009 0.0018
Giardia lamblia Proteasome subunit beta type 2 0.009 0.0114 0.0315
Toxoplasma gondii hypothetical protein 0.0421 0.0781 0.1851
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0384 0.0706 0.2471
Echinococcus multilocularis calumenin 0.0234 0.0405 0.0405
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0181 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0064 0.0061 0.0059
Brugia malayi Integrin alpha pat-2 precursor 0.0185 0.0305 0.0303
Trypanosoma brucei proteasome subunit beta type-2, putative 0.009 0.0114 0.0267
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.023 0.0397 0.0938
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0384 0.0706 0.0706
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0234 0.0405 0.0403
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Loa Loa (eye worm) hypothetical protein 0.0054 0.0042 0.0041
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0248 0.0432 0.1202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1449 0.2852 0.7966
Toxoplasma gondii histone deacetylase SIR2 0.0066 0.0066 0.0154
Leishmania major proteasome alpha 2 subunit, putative 0.004 0.0013 0.0028
Trypanosoma brucei Aph-1 protein, putative 0.0105 0.0145 0.034
Trypanosoma cruzi metacaspase, putative 0.014 0.0214 0.0212
Trypanosoma brucei histone deacetylase, putative 0.0104 0.0143 0.0335
Brugia malayi Proteasome A-type and B-type family protein 0.004 0.0013 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0258 0.0452 0.0451
Toxoplasma gondii aspartyl protease 0.0054 0.0042 0.0097
Brugia malayi Proteasome subunit alpha type 1 0.004 0.0013 0.0012
Onchocerca volvulus 0.0058 0.005 0.0086
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0141 0.0217 0.051
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.004 0.0013 0.0013
Echinococcus granulosus neurocalcin 0.023 0.0397 0.0397
Leishmania major i/6 autoantigen-like protein 0.023 0.0397 0.0938
Entamoeba histolytica glycogen phosphorylase, putative 0.0117 0.0169 0.0586
Echinococcus multilocularis programmed cell death protein 0.0238 0.0411 0.0411
Brugia malayi Cathepsin L-like precursor 0.1449 0.2852 0.2851
Schistosoma mansoni glycogen phosphorylase 0.0117 0.0169 0.0169
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0426 0.0791 0.0791
Echinococcus granulosus proteasome prosome macropain 0.0248 0.0432 0.0432
Echinococcus multilocularis Proteasome, subunit alpha beta 0.004 0.0013 0.0013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0299 0.0536 0.1493
Onchocerca volvulus 0.0384 0.0706 0.1461
Entamoeba histolytica cysteine protease, putative 0.0816 0.1576 0.5523
Loa Loa (eye worm) proteasome subunit alpha type 1 0.004 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0177 0.0289 0.0289
Trypanosoma brucei metacaspase 5, putative 0.014 0.0214 0.0504
Schistosoma mansoni gamma-secretase subunit aph-1 0.027 0.0477 0.0477
Echinococcus multilocularis calpain A 0.4079 0.8151 0.8151
Echinococcus multilocularis caspase 2 0.0322 0.0581 0.0581
Schistosoma mansoni cellular tumor antigen P53 0.0058 0.005 0.005
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.014 0.0214 0.0593
Echinococcus multilocularis Proteasome subunit alpha type 7 0.004 0.0013 0.0013
Schistosoma mansoni hemoglobinase (C13 family) 0.0147 0.023 0.023
Echinococcus granulosus cathepsin L cysteine protease 0.0816 0.1576 0.1576
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Onchocerca volvulus 0.0181 0.0298 0.0605
Echinococcus granulosus histone deacetylase 1 0.0093 0.012 0.012
Trypanosoma cruzi cysteine peptidase, putative 0.1505 0.2964 0.2963
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0054 0.0042 0.0042
Echinococcus multilocularis acylamino acid releasing enzyme 0.0299 0.0536 0.0536
Echinococcus multilocularis glycoprotein Antigen 5 0.0181 0.0298 0.0298
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0223 0.0223
Trichomonas vaginalis esterase, putative 0.0038 0.0009 0.0022
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.4075 0.8144 0.8144
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.014 0.0214 0.0212
Entamoeba histolytica cysteine protease, putative 0.0384 0.0706 0.2471
Brugia malayi EF hand family protein 0.0234 0.0405 0.0403
Leishmania major calpain family cysteine protease-like protein 0.0421 0.0781 0.1851
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.004 0.0013 0.0012
Loa Loa (eye worm) transcription factor SMAD2 0.0133 0.02 0.0198
Toxoplasma gondii PAN domain-containing protein 0.0046 0.0025 0.0054
Plasmodium vivax vivapain-2 0.1449 0.2852 1
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.004 0.0013 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0384 0.0706 0.1968
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.004 0.0013 0.0013
Echinococcus granulosus cathepsin L 0.0816 0.1576 0.1576
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.078
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0384 0.0706 0.2471
Schistosoma mansoni calmodulin 0.023 0.0397 0.0397
Echinococcus multilocularis enteropeptidase 0.0181 0.0298 0.0298
Brugia malayi Protein kinase domain containing protein 0.007 0.0075 0.0073
Onchocerca volvulus Histone deacetylase 10 homolog 0.0045 0.0023 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1505 0.2964 0.7034
Loa Loa (eye worm) hypothetical protein 0.0384 0.0706 0.0704
Plasmodium falciparum plasmepsin III 0.0054 0.0042 0.0143
Brugia malayi calpain 5 0.1019 0.1985 0.1984
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1449 0.2852 0.7966
Trichomonas vaginalis histone deacetylase, putative 0.0093 0.012 0.033
Schistosoma mansoni rab 0.023 0.0397 0.0397
Onchocerca volvulus 0.0064 0.0061 0.0108
Echinococcus granulosus tissue type plasminogen activator 0.007 0.0075 0.0075
Brugia malayi cathepsin F-like cysteine proteinase 0.0432 0.0803 0.0801
Leishmania major histone deacetylase, putative 0.0093 0.012 0.0281
Loa Loa (eye worm) hypothetical protein 0.0281 0.0499 0.0497
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0384 0.0706 0.1968
Loa Loa (eye worm) hypothetical protein 0.0285 0.0508 0.0506
Echinococcus granulosus enteropeptidase 0.0181 0.0298 0.0298
Trypanosoma brucei calpain-like protein, putative 0.144 0.2834 0.6725
Schistosoma mansoni cercarial elastase (S01 family) 0.0181 0.0298 0.0298
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0066 0.0066 0.0227
Mycobacterium tuberculosis Long conserved protein 0.0443 0.0824 0.2263
Schistosoma mansoni chromatin regulatory protein sir2 0.0066 0.0066 0.0066
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0421 0.0781 0.1851
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0013 0.0033
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0061 0.014
Echinococcus multilocularis prolyl endopeptidase 0.2125 0.4213 0.4213
Echinococcus granulosus calcium uptake protein 1 0.0234 0.0405 0.0405
Brugia malayi PAN domain containing protein 0.0046 0.0025 0.0023
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.004 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0421 0.0781 0.0781

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.003 uM In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa ChEMBL. 11392540
IC50 (binding) = 0.003 uM In vitro inhibitory activity against blockage of binding of fibrinogen to purified human GPIIbIIIa ChEMBL. 11392540
IC50 (functional) = 0.179 uM In vitro ability to inhibit the aggregation of ADP-stimulated human platelets ChEMBL. 11392540
IC50 (functional) = 0.179 uM In vitro ability to inhibit the aggregation of ADP-stimulated human platelets ChEMBL. 11392540

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11392540

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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