Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG | 0.0174 | 0.1023 | 0.5 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1266 | 1 | 1 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.1266 | 1 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.1092 | 0.8568 | 0.8564 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.1092 | 0.8568 | 0.8564 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.1023 | 0.1003 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-13 | 0.0174 | 0.1023 | 0.1003 |
Echinococcus granulosus | FK506 binding protein 8 38 kDa | 0.0174 | 0.1023 | 0.1003 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.1023 | 0.1003 |
Leishmania major | fk506-binding protein 1-like protein | 0.1266 | 1 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type, putative | 0.1266 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0062 | 0.0104 | 0.0082 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.1266 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0062 | 0.0104 | 0.0082 |
Toxoplasma gondii | peptidyl-prolyl isomerase FKBP12, putative | 0.0174 | 0.1023 | 0.5 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0062 | 0.0104 | 0.0082 |
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase FKBP35 | 0.1266 | 1 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 | 0.0174 | 0.1023 | 0.1003 |
Onchocerca volvulus | 0.0174 | 0.1023 | 0.5 | |
Schistosoma mansoni | fk506 binding protein | 0.0174 | 0.1023 | 0.1003 |
Trypanosoma brucei | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1266 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0174 | 0.1023 | 0.5 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 | 0.0174 | 0.1023 | 0.1003 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-33 | 0.0174 | 0.1023 | 0.1003 |
Schistosoma mansoni | immunophilin | 0.1092 | 0.8568 | 0.8564 |
Mycobacterium tuberculosis | Probable trigger factor (TF) protein Tig | 0.0174 | 0.1023 | 1 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase, putative | 0.1266 | 1 | 1 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.1266 | 1 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.1266 | 1 | 1 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.1266 | 1 | 1 |
Echinococcus multilocularis | fk506 binding protein | 0.1266 | 1 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.1266 | 1 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, FKBP-type , putative | 0.1266 | 1 | 1 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0062 | 0.0104 | 0.0082 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0174 | 0.1023 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0069 | 0.016 | 0.0138 |
Onchocerca volvulus | 0.0174 | 0.1023 | 0.5 | |
Schistosoma mansoni | immunophilin | 0.1266 | 1 | 1 |
Echinococcus granulosus | FK506 binding protein 2 | 0.0174 | 0.1023 | 0.1003 |
Mycobacterium ulcerans | hypothetical protein | 0.0174 | 0.1023 | 0.1023 |
Chlamydia trachomatis | peptidyl-prolyl cis-trans isomerase | 0.0174 | 0.1023 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0174 | 0.1023 | 0.5 |
Schistosoma mansoni | immunophilin | 0.1266 | 1 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0062 | 0.0104 | 0.0082 |
Leishmania major | peptidylprolyl isomerase-like protein | 0.1266 | 1 | 1 |
Plasmodium vivax | 70 kDa peptidylprolyl isomerase, putative | 0.1266 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0062 | 0.0104 | 0.0082 |
Echinococcus multilocularis | FK506 binding protein 8, 38 kDa | 0.0174 | 0.1023 | 0.1003 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.1266 | 1 | 1 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) | 0.0174 | 0.1023 | 0.1023 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-30 | 0.0174 | 0.1023 | 0.1003 |
Giardia lamblia | FKBP-type peptidyl-prolyl cis-trans isomerase | 0.1266 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0062 | 0.0104 | 0.0082 |
Giardia lamblia | 70 kDa peptidylprolyl isomerase, putative | 0.1266 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0069 | 0.016 | 0.0138 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0062 | 0.0104 | 0.0082 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.1266 | 1 | 1 |
Trypanosoma cruzi | FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative | 0.1266 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0062 | 0.0104 | 0.0082 |
Wolbachia endosymbiont of Brugia malayi | FKBP-type peptidylprolyl isomerase | 0.0174 | 0.1023 | 0.5 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0069 | 0.016 | 0.0138 |
Loa Loa (eye worm) | FKBP5 protein | 0.1266 | 1 | 1 |
Toxoplasma gondii | peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein | 0.0174 | 0.1023 | 0.5 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0062 | 0.0104 | 0.0082 |
Loa Loa (eye worm) | hypothetical protein | 0.1092 | 0.8568 | 0.8564 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 | 0.0174 | 0.1023 | 0.1003 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.1266 | 1 | 1 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.1266 | 1 | 1 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.1266 | 1 | 1 |
Trichomonas vaginalis | immunophilin, putative | 0.1266 | 1 | 1 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.1266 | 1 | 1 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase, putative | 0.1266 | 1 | 1 |
Echinococcus multilocularis | 0.0174 | 0.1023 | 0.1003 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0062 | 0.0104 | 0.0082 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.