Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0172 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0059 | 0.0722 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0149 | 0.2734 | 0.4519 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0578 | 0.0542 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0485 | 0.0449 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0096 | 0.1546 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0063 | 0.0431 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.1196 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0126 | 0.2216 | 0.2186 |
Onchocerca volvulus | 0.0038 | 0.0236 | 0.0294 | |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0096 | 0.1546 | 0.1514 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.0574 | 0.0999 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.005 | 0.0505 | 0.0747 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0059 | 0.0722 | 0.1194 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0295 | 0.6026 | 0.6011 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0098 | 0.1596 | 0.2362 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.0591 | 0.0555 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0126 | 0.2216 | 0.2186 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 0.1771 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.0574 | 0.0849 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0236 | 0.0199 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0063 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0088 | 0.1379 | 1 |
Plasmodium falciparum | transporter, putative | 0.005 | 0.0505 | 0.4161 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0063 | 0.0104 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0192 | 0.3708 | 0.5487 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0126 | 0.2216 | 0.3279 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0126 | 0.2216 | 0.2186 |
Onchocerca volvulus | 0.005 | 0.0505 | 0.0749 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0047 | 0.0457 | 0.1684 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Onchocerca volvulus | 0.0126 | 0.2216 | 0.365 | |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0126 | 0.2216 | 0.3279 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.0574 | 0.0999 |
Plasmodium vivax | amine transporter, putative | 0.005 | 0.0505 | 0.3605 |
Brugia malayi | Bromodomain containing protein | 0.0084 | 0.1273 | 0.124 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0154 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0126 | 0.2216 | 0.3661 |
Schistosoma mansoni | lamin | 0.0054 | 0.06 | 0.0992 |
Onchocerca volvulus | 0.0048 | 0.0467 | 0.0686 | |
Brugia malayi | intermediate filament protein | 0.0054 | 0.06 | 0.0565 |
Echinococcus multilocularis | serotonin transporter | 0.0292 | 0.5961 | 0.8822 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0486 | 0.045 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0292 | 0.5961 | 0.9852 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0054 | 0.06 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.1196 | 0.1163 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0236 | 0.0281 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0126 | 0.2216 | 0.3279 |
Echinococcus granulosus | intermediate filament protein | 0.0054 | 0.06 | 0.0888 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0149 | 0.2734 | 0.4046 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0468 | 0.0692 |
Schistosoma mansoni | jumonji domain containing protein | 0.0078 | 0.1142 | 0.1888 |
Onchocerca volvulus | 0.0038 | 0.0236 | 0.0294 | |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0834 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0126 | 0.2216 | 0.2186 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0126 | 0.2216 | 0.3279 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.0469 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0154 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.005 | 0.0505 | 0.0747 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0079 | 0.1163 | 0.7123 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0098 | 0.1596 | 0.2362 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0149 | 0.2734 | 0.4046 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0059 | 0.0722 | 0.1069 |
Brugia malayi | nuclear receptor RXR | 0.0066 | 0.0882 | 0.0848 |
Echinococcus multilocularis | tumor protein p63 | 0.0327 | 0.6757 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.0574 | 0.4744 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0216 | 0.0178 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0468 | 0.0431 |
Schistosoma mansoni | coup transcription factor | 0.0126 | 0.2216 | 0.3661 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0126 | 0.2216 | 0.3661 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0278 | 0.0241 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.043 | 0.0394 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0214 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.172 | 0.1688 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0236 | 0.0199 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.1196 | 0.1977 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.005 | 0.0505 | 0.0834 |
Onchocerca volvulus | 0.005 | 0.0505 | 0.0749 | |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0747 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0505 | 0.3605 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0066 | 0.0882 | 0.1306 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.005 | 0.0505 | 0.0834 |
Echinococcus multilocularis | tar DNA binding protein | 0.0192 | 0.3721 | 0.5507 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0154 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0637 | 0.0601 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0505 | 0.3605 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.1546 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0248 | 0.0411 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.1196 | 0.8664 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.0485 | 0.0718 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0834 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0192 | 0.3708 | 0.5487 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0467 | 0.0773 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0126 | 0.2216 | 0.3279 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0468 | 0.0692 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0216 | 0.0356 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0236 | 0.0915 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0637 | 0.1052 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0236 | 0.0915 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0126 | 0.2216 | 0.2186 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0236 | 0.0281 |
Echinococcus granulosus | lamin dm0 | 0.0054 | 0.06 | 0.0888 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.005 | 0.0505 | 0.0469 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0088 | 0.1379 | 0.2041 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0248 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Echinococcus granulosus | serotonin transporter | 0.0292 | 0.5961 | 0.8822 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0678 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0637 | 0.0942 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0126 | 0.2216 | 0.2186 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0126 | 0.2216 | 0.2186 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.005 | 0.0505 | 0.0747 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0292 | 0.5961 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0295 | 0.6026 | 0.9958 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0637 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.0485 | 0.0801 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0066 | 0.0882 | 0.0848 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0126 | 0.2216 | 0.3661 |
Brugia malayi | nuclear receptor NHR-88 | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0236 | 0.0391 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0236 | 0.0281 |
Loa Loa (eye worm) | serotonin transporter b | 0.0292 | 0.5961 | 0.5946 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0066 | 0.0882 | 0.1306 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0236 | 0.1896 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.0469 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0096 | 0.1546 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0236 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0126 | 0.2216 | 0.3279 |
Brugia malayi | Isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0067 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0236 | 0.0281 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0088 | 0.1379 | 1 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0637 | 0.0942 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0126 | 0.2216 | 0.3279 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0126 | 0.2216 | 0.2186 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0236 | 0.0281 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0059 | 0.0722 | 0.1069 |
Brugia malayi | TAR-binding protein | 0.0192 | 0.3721 | 0.3697 |
Giardia lamblia | Kinase, PLK | 0.0096 | 0.1546 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.1196 | 0.8664 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3721 | 0.615 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0248 | 0.0211 |
Brugia malayi | ecdysone receptor | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.005 | 0.0512 | 0.0846 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.0485 | 0.0449 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0292 | 0.5961 | 0.5946 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0151 | 0.2798 | 0.2771 |
Schistosoma mansoni | intermediate filament proteins | 0.0054 | 0.06 | 0.0992 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0236 | 0.035 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0032 | 0.0104 | 0.0782 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0468 | 0.0773 |
Brugia malayi | nuclear receptor RXR | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0468 | 0.0773 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0236 | 0.0281 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0126 | 0.2216 | 0.3661 |
Loa Loa (eye worm) | TAR-binding protein | 0.0192 | 0.3721 | 0.3697 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0236 | 0.0281 |
Echinococcus granulosus | tumor protein p63 | 0.0327 | 0.6757 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0292 | 0.5961 | 0.9852 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0059 | 0.0722 | 0.0687 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0126 | 0.2216 | 0.3279 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0292 | 0.5961 | 0.5946 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.172 | 0.2842 |
Schistosoma mansoni | thyroid hormone receptor | 0.0126 | 0.2216 | 0.3661 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.053 | 0.0494 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.5961 | 0.5946 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0236 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.5961 | 0.5946 |
Plasmodium vivax | hypothetical protein, conserved | 0.005 | 0.0505 | 0.3605 |
Schistosoma mansoni | zinc finger protein | 0.0059 | 0.0722 | 0.1194 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Brugia malayi | PHD-finger family protein | 0.0033 | 0.0123 | 0.0085 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0485 | 0.0449 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0236 | 0.0915 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0295 | 0.6026 | 0.8918 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0151 | 0.2798 | 0.2771 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0063 | 0.0374 |
Echinococcus granulosus | FTZ F1 alpha | 0.0126 | 0.2216 | 0.3279 |
Schistosoma mansoni | kinase | 0.0049 | 0.0485 | 0.0802 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0126 | 0.2216 | 0.3279 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.005 | 0.0505 | 0.0747 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.0485 | 0.0716 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0468 | 0.0773 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0032 | 0.0104 | 0.0678 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 0.1771 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0151 | 0.2798 | 0.2771 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0126 | 0.2216 | 0.3661 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0063 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.5961 | 0.5946 |
Onchocerca volvulus | 0.0059 | 0.0722 | 0.1118 | |
Loa Loa (eye worm) | DR-78 | 0.0059 | 0.0722 | 0.0687 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Brugia malayi | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Plasmodium falciparum | amino acid transporter, putative | 0.005 | 0.0505 | 0.4161 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0126 | 0.2216 | 0.2186 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.005 | 0.0505 | 0.0747 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.2798 | 0.2771 |
Schistosoma mansoni | nuclear receptor | 0.0059 | 0.0722 | 0.1194 |
Brugia malayi | nuclear hormone receptor | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | RNA binding protein | 0.0192 | 0.3721 | 0.3697 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0126 | 0.2216 | 0.3661 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0059 | 0.0722 | 0.1194 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0149 | 0.2734 | 0.4519 |
Brugia malayi | steroid hormone receptor | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.0469 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0059 | 0.0722 | 0.1069 |
Brugia malayi | tailless protein | 0.0059 | 0.0722 | 0.0687 |
Echinococcus multilocularis | peregrin | 0.004 | 0.0278 | 0.0412 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0126 | 0.2216 | 0.3279 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.005 | 0.0505 | 0.0747 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0126 | 0.2216 | 0.365 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3721 | 0.615 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.005 | 0.0505 | 0.0747 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0063 | 0.0025 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0834 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.3605 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0126 | 0.2216 | 0.2186 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.1196 | 0.8664 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0236 | 0.0199 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0059 | 0.0722 | 0.1069 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0216 | 0.0319 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.0485 | 0.0718 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.0469 |
Brugia malayi | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0079 | 0.1163 | 0.7419 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0059 | 0.0722 | 0.1069 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0236 | 0.0281 |
Schistosoma mansoni | bromodomain containing protein | 0.0072 | 0.1004 | 0.1659 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0236 | 0.0199 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | conserved hypotetical protein | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0236 | 0.0281 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0059 | 0.0722 | 0.1069 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0126 | 0.2216 | 0.2186 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0471 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0063 | 0.0374 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0678 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0066 | 0.0882 | 0.0848 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0096 | 0.1546 | 0.2555 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0126 | 0.2216 | 0.3661 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0192 | 0.3721 | 0.5507 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0149 | 0.2734 | 0.2707 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0096 | 0.1546 | 0.1514 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0236 | 0.0199 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0126 | 0.2216 | 0.3661 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0216 | 0.0356 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0922 | 0.1364 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0032 | 0.0104 | 0.0154 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0248 | 0.0411 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0149 | 0.2734 | 0.4519 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0126 | 0.2216 | 0.2186 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.3605 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.0485 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.1546 | 1 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0747 |
Loa Loa (eye worm) | RNA binding protein | 0.0192 | 0.3721 | 0.3697 |
Loa Loa (eye worm) | intermediate filament protein | 0.0054 | 0.06 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0059 | 0.0722 | 0.0687 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0922 | 0.1364 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0126 | 0.2216 | 0.2186 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0236 | 0.0281 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0126 | 0.2216 | 0.2186 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0236 | 0.035 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0468 | 0.0431 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0066 | 0.0882 | 0.0848 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0834 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.005 | 0.0505 | 0.0834 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0059 | 0.0722 | 0.1069 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0054 | 0.06 | 0.0565 |
Onchocerca volvulus | 0.0049 | 0.0485 | 0.0716 | |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0047 | 0.0457 | 0.1684 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0241 | 0.4803 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.3605 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0271 | 0.0234 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.005 | 0.0505 | 0.0469 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0236 | 0.0199 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0149 | 0.2734 | 0.4046 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0637 | 0.0601 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 0.1991 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0059 | 0.0722 | 0.0687 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0192 | 0.3721 | 0.3697 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0059 | 0.0722 | 0.1069 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0468 | 0.0773 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0063 | 0.0104 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0544 | 0.0508 |
Schistosoma mansoni | nuclear receptor | 0.0059 | 0.0722 | 0.1194 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0292 | 0.5961 | 0.5946 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0236 | 0.0391 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0066 | 0.0882 | 0.1458 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0126 | 0.2216 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0236 | 0.0199 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0096 | 0.1546 | 0.2515 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.078 | 0.0745 |
Schistosoma mansoni | thyroid hormone receptor | 0.0126 | 0.2216 | 0.3661 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.1546 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0126 | 0.2216 | 0.365 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0485 | 0.0801 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0149 | 0.2734 | 0.4046 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0248 | 0.0368 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0126 | 0.2216 | 0.3279 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0059 | 0.0722 | 0.1069 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0214 | 0.0317 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3721 | 0.615 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0126 | 0.2216 | 0.3279 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0059 | 0.0722 | 0.0687 |
Brugia malayi | nuclear receptor NHR-67 | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0126 | 0.2216 | 0.3661 |
Onchocerca volvulus | 0.005 | 0.0505 | 0.0749 | |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0467 | 0.0431 |
Onchocerca volvulus | 0.0054 | 0.06 | 0.0911 | |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.005 | 0.0505 | 0.0834 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Schistosoma mansoni | nuclear hormone receptor | 0.0059 | 0.0722 | 0.1194 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0485 | 0.0801 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0468 | 0.0431 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.1014 | 0.098 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0236 | 0.1643 |
Loa Loa (eye worm) | acetyltransferase | 0.0295 | 0.6026 | 0.6011 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.6051 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0468 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0063 | 0.0025 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0059 | 0.0722 | 0.1069 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0485 | 0.0449 |
Echinococcus multilocularis | lamin | 0.0054 | 0.06 | 0.0888 |
Onchocerca volvulus | 0.0054 | 0.06 | 0.0911 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0236 | 0.1896 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0126 | 0.2216 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0327 | 0.0483 |
Brugia malayi | ecdysteroid receptor | 0.0126 | 0.2216 | 0.2186 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.1596 | 0.1564 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0059 | 0.0722 | 0.1118 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0236 | 0.0199 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0468 | 0.0692 |
Brugia malayi | isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0067 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0468 | 0.0692 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.005 | 0.0505 | 0.0834 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.005 | 0.0505 | 0.0747 |
Onchocerca volvulus | 0.0059 | 0.0722 | 0.1118 | |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.005 | 0.0505 | 0.0747 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0722 | 0.0687 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0637 | 0.0942 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0468 | 0.0431 |
Onchocerca volvulus | 0.0038 | 0.0236 | 0.0294 | |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0059 | 0.0722 | 0.1069 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0126 | 0.2216 | 0.365 |
Echinococcus granulosus | lamin | 0.0054 | 0.06 | 0.0888 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0126 | 0.2216 | 0.3279 |
Schistosoma mansoni | lamin | 0.0054 | 0.06 | 0.0992 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0284 | 0.5787 | 0.8564 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.0485 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | nuclear hormone receptor | 0.0126 | 0.2216 | 0.3661 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0088 | 0.1379 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0054 | 0.06 | 0.0888 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0096 | 0.1546 | 0.2288 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0088 | 0.1379 | 0.8723 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0236 | 0.0199 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0126 | 0.2216 | 0.2186 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3721 | 0.615 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.0205 | 0.0303 |
Schistosoma mansoni | nuclear hormone receptor | 0.0059 | 0.0722 | 0.1194 |
Trypanosoma brucei | polo-like protein kinase | 0.0096 | 0.1546 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0059 | 0.0722 | 0.1118 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.172 | 0.1688 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0126 | 0.2216 | 0.2186 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0236 | 0.0915 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0126 | 0.2216 | 0.2186 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.06 | 0.0565 |
Echinococcus granulosus | peregrin | 0.004 | 0.0278 | 0.0412 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.0591 | 0.0555 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0192 | 0.3721 | 0.3697 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.0574 | 0.0849 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0126 | 0.2216 | 0.2186 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0505 | 0.0469 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0236 | 0.1643 |
Echinococcus multilocularis | musashi | 0.0054 | 0.06 | 0.0888 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0063 | 0.0025 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0059 | 0.0722 | 0.0687 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0637 | 0.0942 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0327 | 0.0483 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0149 | 0.2734 | 0.2707 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0066 | 0.0882 | 0.1458 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.1196 | 0.1163 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0126 | 0.2216 | 0.3279 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0088 | 0.1379 | 0.8723 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0096 | 0.1546 | 0.2288 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0059 | 0.0722 | 0.1194 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0468 | 0.0692 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0079 | 0.1163 | 0.9722 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0032 | 0.0104 | 0.0154 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.1196 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0216 | 0.0319 |
Brugia malayi | nuclear hormone receptor | 0.0059 | 0.0722 | 0.0687 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0236 | 0.0199 |
Schistosoma mansoni | tar DNA-binding protein | 0.0192 | 0.3721 | 0.615 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0126 | 0.2216 | 0.2186 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0126 | 0.2216 | 0.3279 |
Onchocerca volvulus | 0.0292 | 0.5961 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0882 | 0.0848 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0126 | 0.2216 | 0.2186 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0063 | 0.0374 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.34 mg kg-1 | Inhibition of tetrabenazine(TBZ)-induced ptosis in mice (administered ip) | ChEMBL. | 6747993 |
ED50 (functional) | = 0.55 mg kg-1 | Inhibition of tetrabenazine(TBZ)-induced depression of motor activity (MA) in mice (administered ip) | ChEMBL. | 6747993 |
Ki (functional) | = 0.16 nM | Inhibition of norepinephrine (NE) into rat brain synaptosomes | ChEMBL. | 6747993 |
Ki (binding) | = 1.5 nM | Inhibition of serotonin (5-HT) uptake into rat brain synaptosomes | ChEMBL. | 6747993 |
Ki (functional) | = 1.7 nM | Inhibition of dopamine (DA) uptake into rat brain synaptosomes | ChEMBL. | 6747993 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.