Detailed information for compound 304774

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 695.068 | Formula: C41H78N2O6
  • H donors: 7 H acceptors: 6 LogP: 11.27 Rotable bonds: 34
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCCCCCCCCCCCCCCC(=O)N[C@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)CNC1C=C(CO)C(C(C1O)O)O
  • InChi: 1S/C41H78N2O6/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-37(45)36(32-42-35-31-34(33-44)39(47)41(49)40(35)48)43-38(46)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,31,35-37,39-42,44-45,47-49H,3-26,28,30,32-33H2,1-2H3,(H,43,46)/b29-27+/t35?,36-,37+,39?,40?,41?/m0/s1
  • InChiKey: MTNOHGIGZSPUKL-JIGJGHPYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus glucosidase, beta, acid Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Brugia malayi O-Glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Onchocerca volvulus Glucosylceramidase homolog Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pre-SET motif family protein 0.0229 0.0134 0.0134
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0022 0.0006 0.0012
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.0422 0.0254 0.0251
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Echinococcus multilocularis steroid dehydrogenase 0.0026 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0009 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0021 0.002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0047 0.0021 0.002
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0072 0.0036 0.0035
Leishmania major DNA polymerase kappa, putative 0.0044 0.0019 0.0036
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0132 0.0074 0.0071
Trypanosoma brucei unspecified product 0.0026 0.0008 0.0011
Plasmodium vivax importin-beta 2, putative 0.0032 0.0011 0.0019
Onchocerca volvulus 0.0032 0.0011 0.0098
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0021 0.0019
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0026 0.0008 0.0005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0015 0.0014
Leishmania major hypothetical protein, conserved 0.0026 0.0008 0.0012
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0072 0.0036 0.0074
Onchocerca volvulus 0.0072 0.0036 0.047
Trichomonas vaginalis DNA polymerase eta, putative 0.0066 0.0033 0.082
Plasmodium vivax peroxiredoxin, putative 0.0093 0.005 0.0103
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0005 0.0004
Schistosoma mansoni aryl hydrocarbon receptor 0.0017 0.0003 0.0001
Loa Loa (eye worm) acetyltransferase 0.0159 0.0091 0.009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0041 0.0017 0.0017
Echinococcus granulosus agrin 0.0021 0.0005 0.0004
Trichomonas vaginalis glutaminase, putative 0.0298 0.0177 0.4703
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0072 0.0036 0.0034
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0001
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Trypanosoma brucei short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Brugia malayi jmjC domain containing protein 0.0017 0.0002 0.0002
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0072 0.0036 0.0034
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.0021 0.002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0037 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0021 0.002
Schistosoma mansoni loxhd1 0.0022 0.0005 0.0004
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0004
Brugia malayi intermediate filament protein 0.003 0.001 0.001
Brugia malayi CXXC zinc finger family protein 0.0032 0.0011 0.0011
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0005 0.0005
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0011 0.0011
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0132 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0026 0.0008 0.0051
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0026 0.0008 0.0012
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.0006 0.0004
Echinococcus granulosus muscleblind protein 0.0164 0.0094 0.0093
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0422 0.0254 0.0253
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0008 0.0012
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0007 0.0007
Echinococcus multilocularis caspase 0.0128 0.0072 0.0071
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0024 0.0023
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0005 0.0004
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.009
Giardia lamblia DINP protein human, muc B family 0.0044 0.0019 0.2971
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0026 0.0008 0.0005
Echinococcus multilocularis retinol dehydrogenase 11 0.0026 0.0008 0.0008
Echinococcus multilocularis microtubule associated protein 2 0.0758 0.0463 0.0462
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0113 0.0062 0.0061
Plasmodium falciparum basic transcription factor 3b, putative 0.0038 0.0016 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0113 0.0062 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0261 0.0154 0.2209
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0026 0.0008 0.0949
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0003 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.0021 0.002
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.0422 0.0254 0.0252
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Brugia malayi oxidoreductase 0.0026 0.0008 0.0008
Leishmania major dehydrogenase-like protein 0.0026 0.0008 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0013 0.0011
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0005 0.0005
Schistosoma mansoni folylpolyglutamate synthase 0.0422 0.0254 0.0252
Loa Loa (eye worm) hypothetical protein 0.0054 0.0026 0.0025
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.0021 0.0021
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0028 0.0009 0.0015
Trypanosoma brucei metacaspase 5, putative 0.0049 0.0022 0.0042
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.0016 0.0028
Entamoeba histolytica ABC transporter, putative 0.0028 0.0009 0.0801
Trichomonas vaginalis hypothetical protein 0.0072 0.0036 0.0914
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0066 0.0033 0.082
Leishmania major hypothetical protein, conserved 0.0028 0.0009 0.0014
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Onchocerca volvulus 0.0045 0.002 0.0224
Schistosoma mansoni single-minded 0.0017 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0086 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0049 0.0022 0.0022
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0005 0.0004
Leishmania major pentamidine resistance protein 1 0.0028 0.0009 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0186 0.4927
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0072 0.0036 0.0034
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0139 0.0078 0.0078
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Schistosoma mansoni multidrug resistance protein 0.0028 0.0009 0.0008
Brugia malayi RNA recognition motif domain containing protein 0.0139 0.0078 0.0078
Echinococcus multilocularis lamin dm0 0.003 0.001 0.001
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0005 0.0005
Brugia malayi hypothetical protein 0.0025 0.0007 0.0007
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0045 0.0043
Echinococcus multilocularis caspase 2 0.0094 0.005 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Entamoeba histolytica short chain dehydrogenase family protein 0.0026 0.0008 0.0593
Brugia malayi glutaminase DH11.1 0.0298 0.0177 0.0177
Entamoeba histolytica short chain dehydrogenase family protein 0.0026 0.0008 0.0593
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0015 0.0015
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0008 0.0012
Chlamydia trachomatis endonuclease IV 0.0084 0.0044 0.0042
Mycobacterium ulcerans short-chain dehydrogenase 0.0026 0.0008 0.0005
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.7452 0.4623 1
Schistosoma mansoni lipoxygenase 0.0022 0.0005 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Schistosoma mansoni rotamase 0.0036 0.0014 0.0013
Toxoplasma gondii isocitrate dehydrogenase 0.0052 0.0024 0.0048
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0072 0.0036 0.0034
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0005 0.0005
Mycobacterium tuberculosis Hypothetical protein 0.0615 0.0374 0.0371
Echinococcus multilocularis retinol dehydrogenase 13 0.0026 0.0008 0.0008
Echinococcus granulosus expressed protein 0.0036 0.0014 0.0014
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0072 0.0036 0.0034
Echinococcus multilocularis thymidylate synthase 0.1107 0.068 0.0679
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0033 0.0033
Onchocerca volvulus Folate transporter 1 homolog 0.0107 0.0058 0.0789
Loa Loa (eye worm) RNA binding protein 0.0139 0.0078 0.0078
Echinococcus granulosus caspase 3 0.008 0.0041 0.0041
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0085 0.0045 0.0045
Leishmania major 3-keto-dihydrosphingosine reductase 0.0026 0.0008 0.0012
Brugia malayi hypothetical protein 0.0022 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.0006 0.0006
Schistosoma mansoni cpg binding protein 0.0033 0.0013 0.0011
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0021 0.002
Brugia malayi RNA binding protein 0.0139 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0005 0.0005
Mycobacterium tuberculosis Possible oxidoreductase 0.0026 0.0008 0.0005
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.001 0.0017
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0008 0.014
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Brugia malayi hypothetical protein 0.0022 0.0006 0.0006
Echinococcus granulosus carbonyl reductase 1 0.0026 0.0008 0.0008
Trypanosoma cruzi metacaspase 5, putative 0.0049 0.0022 0.0042
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0026 0.0008 0.0005
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0052 0.0024 0.0046
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.1107 0.068 0.0678
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0028 0.0009 0.0015
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0003 0.0002
Schistosoma mansoni jumonji domain containing protein 0.0065 0.0032 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0003 0.0001
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.004 0.0017 0.0017
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0014 0.0024
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.1107 0.068 0.0678
Mycobacterium ulcerans dehydrogenase/reductase 0.0026 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Schistosoma mansoni importin beta-1 0.0032 0.0011 0.001
Echinococcus multilocularis muscleblind protein 0.0164 0.0094 0.0093
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0021 0.0494
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.0037 0.0037
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0001
Brugia malayi SPARC precursor 0.0021 0.0005 0.0005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0021 0.0021
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0072 0.0036 0.0074
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0031 0.0011 0.001
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0004
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0026 0.0008 0.0012
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0001
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0052 0.0024 0.0046
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0422 0.0254 0.0253
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0026 0.0008 0.0012
Onchocerca volvulus 0.0033 0.0013 0.0116
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0024 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0022 0.0523
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0072 0.0036 0.0034
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0014
Brugia malayi hypothetical protein 0.0025 0.0007 0.0007
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0002 0.0002
Brugia malayi jmjC domain containing protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.0026 0.0008 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Echinococcus multilocularis expressed protein 0.041 0.0247 0.0246
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0118 0.0065 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Loa Loa (eye worm) hypothetical protein 0.0164 0.0094 0.0093
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0024 0.0023
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0024 0.0047
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0003 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0003 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0037
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0003 0.0002
Brugia malayi Muscleblind-like protein 0.0164 0.0094 0.0094
Brugia malayi small heat shock protein 0.0634 0.0386 0.0386
Echinococcus granulosus multidrug resistance associated protein 4 0.0022 0.0005 0.0005
Echinococcus multilocularis survival motor neuron protein 1 0.026 0.0153 0.0153
Brugia malayi RNA, U transporter 1 0.009 0.0048 0.0048
Echinococcus granulosus hypothetical protein 0.0026 0.0008 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0891 0.0545 0.0545
Echinococcus granulosus lamin dm0 0.003 0.001 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0164 0.0094 0.0093
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0075 0.0038 0.0966
Loa Loa (eye worm) nuclear hormone receptor 0.0022 0.0006 0.0005
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0018 0.0017
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0052 0.0024 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Mycobacterium leprae Probable oxidoreductase 0.0026 0.0008 0.0006
Loa Loa (eye worm) dehydrogenase 0.0026 0.0008 0.0008
Plasmodium falciparum glutathione reductase 0.0052 0.0024 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0006 0.0012
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0085 0.0045 0.0044
Onchocerca volvulus 0.0031 0.0011 0.0089
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0002 0.0001
Entamoeba histolytica hypothetical protein 0.0107 0.0058 0.8853
Schistosoma mansoni hypothetical protein 0.0045 0.002 0.0018
Trichomonas vaginalis peroxiredoxin, putative 0.0024 0.0007 0.011
Schistosoma mansoni caspase-7 (C14 family) 0.0094 0.005 0.0048
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0009 0.0014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0026 0.0025
Echinococcus multilocularis steroid dehydrogenase 0.0026 0.0008 0.0008
Schistosoma mansoni organic anion transporter 0.0031 0.0011 0.0009
Echinococcus multilocularis dna polymerase eta 0.0065 0.0032 0.0032
Onchocerca volvulus 0.0098 0.0053 0.0713
Schistosoma mansoni lamin 0.003 0.001 0.0009
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Schistosoma mansoni ap endonuclease 0.0021 0.0005 0.0003
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0072 0.0036 0.0075
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.0021 0.0242
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Echinococcus granulosus dna polymerase eta 0.0065 0.0032 0.0032
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.0006 0.0005
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0615 0.0374 0.0804
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0005 0.0004
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0042
Loa Loa (eye worm) intermediate filament protein 0.003 0.001 0.001
Trypanosoma cruzi metacaspase 5, putative 0.0049 0.0022 0.0042
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0072 0.0036 0.0034
Loa Loa (eye worm) glutaminase 0.0298 0.0177 0.0177
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0003 0.0003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0005 0.03
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0026 0.0008 0.0012
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0031 0.0011 0.001
Loa Loa (eye worm) ICD-1 protein 0.0038 0.0016 0.0015
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Brugia malayi hypothetical protein 0.0031 0.0011 0.0011
Trichomonas vaginalis DNA helicase recq, putative 0.005 0.0023 0.0541
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0118 0.0065 0.0062
Schistosoma mansoni caspase-3 (C14 family) 0.0128 0.0072 0.007
Plasmodium falciparum metacaspase 1 0.0049 0.0022 0.0042
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0026 0.0008 0.0005
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0085 0.0045 0.0091
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0011 0.0011
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.0037 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0012 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0052 0.0024 0.0023
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0014
Mycobacterium ulcerans thiol peroxidase 0.0024 0.0007 0.0004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0032 0.0066
Schistosoma mansoni microtubule-associated protein tau 0.0758 0.0463 0.0461
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0005 0.0005
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0016 0.003
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0007 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0005 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Echinococcus multilocularis apoptotic protease activating factor 1 0.0045 0.002 0.0019
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.004 0.0017 0.0017
Echinococcus multilocularis carbonyl reductase 1 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0031 0.0011 0.0089
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 0.1681
Loa Loa (eye worm) hypothetical protein 0.0033 0.0013 0.0012
Mycobacterium ulcerans ketoacyl reductase 0.0026 0.0008 0.0005
Echinococcus multilocularis dihydrofolate reductase 1.6105 1 1
Treponema pallidum folylpolyglutamate synthetase (folC) 0.0422 0.0254 1
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0026 0.0008 0.0008
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0027 0.0024
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0005 0.0004
Mycobacterium ulcerans oxidoreductase 0.0072 0.0036 0.0034
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0033 0.0012 0.0023
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0021 0.0021
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.0021 0.002
Leishmania major short chain dehydrogenase-like protein 0.0026 0.0008 0.0012
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Schistosoma mansoni cpg binding protein 0.0032 0.0011 0.001
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0422 0.0254 0.0544
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0005 0.0006
Brugia malayi Pre-SET motif family protein 0.0033 0.0013 0.0013
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0015 0.1692
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0009 0.0801
Brugia malayi aryl hydrocarbon receptor AHR-1 0.004 0.0017 0.0017
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0005 0.0003
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0078 0.0076
Brugia malayi ecdysteroid receptor 0.0047 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.0021 0.0021
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0128 0.0072 0.0071
Echinococcus granulosus thymidylate synthase 0.1107 0.068 0.0679
Leishmania major metacaspase, putative 0.0049 0.0022 0.0042
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0021 0.0042
Trypanosoma cruzi DNA polymerase eta, putative 0.0065 0.0032 0.0064
Trypanosoma cruzi metacaspase, putative 0.0049 0.0022 0.0042
Echinococcus multilocularis bloom syndrome protein 0.005 0.0023 0.0022
Entamoeba histolytica hypothetical protein 0.0026 0.0008 0.0593
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0003 0.0002
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0072 0.0036 0.0034
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0028 0.0009 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.0021 0.002
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0005 0.0392
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0022 0.0523
Mycobacterium tuberculosis Probable thiol peroxidase Tpx 0.0024 0.0007 0.0004
Echinococcus granulosus caspase 2 0.0094 0.005 0.0049
Leishmania major biopterin transporter, putative;with=GeneDB:LinJ35_V3.5120 0.0487 0.0295 0.0632
Schistosoma mansoni nuclear receptor 0.0022 0.0006 0.0004
Plasmodium falciparum metacaspase-like protein 0.0049 0.0022 0.0042
Leishmania major p-glycoprotein e 0.0028 0.0009 0.0015
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Onchocerca volvulus 0.0031 0.0011 0.0089
Onchocerca volvulus Folate transporter 1 homolog 0.0107 0.0058 0.0789
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.0021 0.0021
Trichomonas vaginalis rotamase, putative 0.0036 0.0014 0.0316
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0026 0.0008 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.0021 0.0019
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.0021 0.0021
Echinococcus granulosus tumor protein p63 0.0371 0.0222 0.0222
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0014
Mycobacterium tuberculosis Possible oxidoreductase 0.0072 0.0036 0.0034
Brugia malayi secreted modular calcium-binding protein 1 0.0021 0.0005 0.0005
Plasmodium vivax basic transcription factor 3b, putative 0.0038 0.0016 0.0028
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0005 0.0002
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0118 0.0065 0.0062
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0026 0.0008 0.0593
Schistosoma mansoni lozenge 0.0061 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0487 0.0294 0.0294
Mycobacterium tuberculosis Probable oxidoreductase 0.0132 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0022 0.0523
Echinococcus multilocularis multidrug resistance associated protein 1 0.0028 0.0009 0.0009
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0014 0.0014
Trichomonas vaginalis set domain proteins, putative 0.0261 0.0154 0.4075
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0026 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0003 0.0001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0024 0.0021
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Brugia malayi thymidylate synthase 0.1107 0.068 0.068
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Brugia malayi isocitrate dehydrogenase 0.0052 0.0024 0.0024
Brugia malayi hypothetical protein 0.0021 0.0005 0.0005
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0078 0.0076
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0026 0.0008 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0084 0.0044 0.009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.0021 0.002
Brugia malayi Importin beta-1 subunit 0.0032 0.0011 0.0011
Echinococcus granulosus GPCR family 2 0.0017 0.0003 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Echinococcus multilocularis carbonyl reductase 1 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0091 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Leishmania major short chain dehydrogenase/reductase, putative 0.0026 0.0008 0.0012
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0043
Loa Loa (eye worm) runx1 0.0061 0.003 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0016 0.0353
Onchocerca volvulus 0.0022 0.0006 0.0012
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0026 0.0008 0.0005
Leishmania major basic transcription factor 3a, putative 0.0038 0.0016 0.0028
Brugia malayi PAS domain containing protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0072 0.0036 0.0074
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0011 0.0089
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0008 0.0005
Schistosoma mansoni hypothetical protein 0.0164 0.0094 0.0092
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 2, putative 0.0369 0.0221 0.0472
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.0037 0.0037
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0052 0.0024 0.0046
Echinococcus multilocularis expressed protein 0.0021 0.0005 0.0004
Brugia malayi hypothetical protein 0.0118 0.0065 0.0065
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0005 0.0003
Schistosoma mansoni ap endonuclease 0.0021 0.0005 0.0003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.0021 0.002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0098 0.0053 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0008 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0017 0.0032
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0107 0.0058 0.0789
Mycobacterium ulcerans glutaminase 0.0298 0.0177 0.0174
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.0037 0.0074
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0025 0.0025
Echinococcus granulosus snurportin 1 0.0338 0.0202 0.0201
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0011 0.0089
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0026 0.0008 0.0012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0003 0.0002
Loa Loa (eye worm) reduced folate carrier family protein 0.0107 0.0058 0.0058
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0016 0.0353
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0113 0.0062 0.0061
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0037 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0014 0.0316
Mycobacterium ulcerans oxidoreductase 0.0026 0.0008 0.0005
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0072 0.0036 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0028 0.0009 0.0017
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.001 0.0008
Plasmodium falciparum steroid dehydrogenase, putative 0.0026 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.7452 0.4623 1
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0021 0.0019
Brugia malayi hypothetical protein 0.0058 0.0028 0.0028
Trypanosoma brucei p-glycoprotein 0.0028 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0009 0.0801
Brugia malayi Doublecortin family protein 0.0022 0.0005 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0013 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0021 0.0021
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Echinococcus multilocularis aryl hydrocarbon receptor 0.0058 0.0028 0.0027
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0371 0.0222 0.0221
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0026 0.0008 0.0007
Schistosoma mansoni organic anion transporter 0.0031 0.0011 0.0009
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0004
Echinococcus granulosus oxidoreductase 0.0026 0.0008 0.0008
Brugia malayi nuclear hormone receptor 0.0047 0.0021 0.0021
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.001 0.001
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0072 0.0036 0.7946
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0026 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0094 0.005 0.005
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0029 0.0029
Schistosoma mansoni follistatin 0.0021 0.0005 0.0003
Brugia malayi hypothetical protein 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0005 0.0004
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0026 0.0008 0.0005
Mycobacterium ulcerans ketoacyl reductase 0.0026 0.0008 0.0005
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0005 0.0007
Leishmania major vacuolar-type proton translocating pyrophosphatase 1, putative 0.0369 0.0221 0.0472
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0026 0.0008 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0026 0.0024
Brugia malayi prostaglandin transporter 0.0031 0.0011 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0007 0.0007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0021 0.0021
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.0019 0.0016
Brugia malayi Dihydrofolate reductase 1.6105 1 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0155 0.0088 0.0087
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0072 0.0036 0.0034
Trypanosoma cruzi MFS transporter, putative 0.0031 0.0011 0.0018
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0072 0.0036 0.0034
Brugia malayi hypothetical protein 0.0031 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0045 0.0092
Schistosoma mansoni dihydropteridine reductase 0.0072 0.0036 0.0035
Loa Loa (eye worm) hypothetical protein 0.003 0.001 0.001
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.0021 0.002
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 1.6105 1 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0029 0.0029
Mycobacterium tuberculosis Possible oxidoreductase 0.0072 0.0036 0.0034
Toxoplasma gondii NAC domain-containing protein 0.0038 0.0016 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Loa Loa (eye worm) hypothetical protein 0.026 0.0153 0.0153
Schistosoma mansoni blooms syndrome DNA helicase 0.0039 0.0016 0.0014
Mycobacterium tuberculosis Possible oxidoreductase 0.0026 0.0008 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0052 0.0024 0.0046
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0008 0.0593
Echinococcus granulosus carbonyl reductase 1 0.0026 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0041
Brugia malayi ImpB/MucB/SamB family protein 0.0065 0.0032 0.0032
Echinococcus granulosus geminin 0.0371 0.0222 0.0222
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0006 0.0005
Schistosoma mansoni hypothetical protein 0.0037 0.0015 0.0013
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.0091 0.0091
Entamoeba histolytica hypothetical protein 0.0118 0.0065 1
Trypanosoma brucei Metacaspase-4 0.0049 0.0022 0.0042
Trypanosoma cruzi metacaspase, putative 0.0049 0.0022 0.0042
Echinococcus granulosus folate receptor beta 0.0915 0.056 0.056
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0007 0.0006
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0026 0.0008 0.0152
Loa Loa (eye worm) hypothetical protein 0.0634 0.0386 0.0386
Brugia malayi Bloom's syndrome protein homolog 0.005 0.0023 0.0023
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0015 0.0014
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0021 0.0019
Entamoeba histolytica hypothetical protein 0.0118 0.0065 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.0037 0.0036
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0005 0.0005
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0003 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Trypanosoma cruzi hypothetical protein 0.0022 0.0005 0.0006
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0049 0.0022 0.0022
Loa Loa (eye worm) DR-78 0.0022 0.0006 0.0005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0118 0.0065 0.0062
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0049 0.0022 0.0044
Mycobacterium tuberculosis Probable reductase 0.0118 0.0065 0.0062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0044 0.0019 0.0035
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0098 0.0053 0.005
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0027 0.0026
Trypanosoma brucei short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0164 0.0094 0.0093
Echinococcus multilocularis cpg binding protein 0.0033 0.0013 0.0012
Loa Loa (eye worm) FolC protein 0.0422 0.0254 0.0254
Onchocerca volvulus 0.0053 0.0025 0.0295
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0002 0.0001
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.0186 0.0185
Brugia malayi hypothetical protein 0.0026 0.0008 0.0008
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0004 0.0003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0131 0.0073 0.0072
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0131 0.0073 0.0073
Echinococcus granulosus Solute carrier organic anion transporter family 0.0031 0.0011 0.001
Plasmodium falciparum V-type H(+)-translocating pyrophosphatase, putative 0.0369 0.0221 0.0472
Entamoeba histolytica recQ family helicase, putative 0.0027 0.0008 0.0604
Entamoeba histolytica multidrug resistance protein, putative 0.0028 0.0009 0.0801
Toxoplasma gondii thioredoxin reductase 0.0052 0.0024 0.0048
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0026 0.0008 0.0008
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.7452 0.4623 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0132 0.0074 0.0071
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0008 0.0005
Trypanosoma brucei metacaspase MCA3 0.0049 0.0022 0.0042
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0005 0.0005
Echinococcus multilocularis geminin 0.0371 0.0222 0.0222
Chlamydia trachomatis dihydrofolate reductase 1.6105 1 1
Echinococcus granulosus multidrug resistance associated protein 7 0.0028 0.0009 0.0009
Brugia malayi folate-like transporter 3 0.0107 0.0058 0.0058
Brugia malayi PXA domain containing protein 0.0021 0.0005 0.0005
Trypanosoma cruzi folylpolyglutamate synthetase 0.0422 0.0254 0.0544
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.7452 0.4623 1
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0031 0.0011 0.001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0062 0.006
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0005 0.0063
Brugia malayi hypothetical protein 0.0018 0.0003 0.0003
Onchocerca volvulus 0.0026 0.0008 0.0051
Schistosoma mansoni carbonyl reductase 0.0026 0.0008 0.0007
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0026 0.0008 0.0012
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.004 0.0017 0.0015
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.0006 0.0004
Loa Loa (eye worm) TAR-binding protein 0.0139 0.0078 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0014 0.0024
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 1 0.0369 0.0221 0.0472
Brugia malayi tailless protein 0.0022 0.0006 0.0006
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0006 0.0003
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0026 0.0008 0.0005
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0005 0.0004
Chlamydia trachomatis oxoacy-ACP reductase 0.0072 0.0036 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0022 0.0523
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.0037 0.0074
Onchocerca volvulus 0.0026 0.0008 0.0051
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0008 0.0005
Echinococcus granulosus retinol dehydrogenase 11 0.0026 0.0008 0.0008
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0072 0.0036 0.0036
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0072 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0017
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0005 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0021 0.0021
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0085 0.0045 0.0044
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0084 0.0044 0.0044
Onchocerca volvulus 0.0487 0.0294 0.4286
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0009 0.0801
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0422 0.0254 0.0253
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0085 0.0045 0.0042
Plasmodium vivax vacuolar-type H+ pumping pyrophosphatase, putative 0.0369 0.0221 0.0472
Schistosoma mansoni lamin 0.003 0.001 0.0009
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0026 0.0008 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0028 0.0009 0.0015
Mycobacterium tuberculosis Probable oxidoreductase 0.0098 0.0053 0.005
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0002 0.0001
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0091 0.0048 0.7212
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.004 0.0017 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0072 0.0036 0.0036
Echinococcus multilocularis snurportin 1 0.0338 0.0202 0.0201
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0017 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0057 0.0027 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0063
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0026 0.0008 0.0012
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0016 0.0032
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0004
Mycobacterium tuberculosis Probable dehydrogenase 0.0118 0.0065 0.0062
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.0021 0.0019
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0021 0.0021
Giardia lamblia Multidrug resistance-associated protein 1 0.0028 0.0009 0.1177
Loa Loa (eye worm) hypothetical protein 0.0045 0.002 0.002
Brugia malayi jmjC domain containing protein 0.0065 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0022 0.0006 0.0003
Onchocerca volvulus 0.0107 0.0058 0.0789
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0012 0.0021
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Echinococcus granulosus cpg binding protein 0.0033 0.0013 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0026 0.0008 0.0014
Brugia malayi ecdysone receptor 0.0022 0.0006 0.0006
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0003 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Onchocerca volvulus 0.0026 0.0008 0.0051
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0052 0.0024 0.0023
Schistosoma mansoni carbonyl reductase 0.0026 0.0008 0.0007
Onchocerca volvulus 0.0026 0.0008 0.0051
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.7452 0.4623 1
Mycobacterium ulcerans dehydrogenase 0.0026 0.0008 0.0005
Loa Loa (eye worm) isocitrate dehydrogenase 0.0052 0.0024 0.0024
Leishmania major DNA polymerase eta, putative 0.0039 0.0016 0.003
Trypanosoma cruzi transcription factor btf3, putative 0.0038 0.0016 0.0028
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.0091 0.009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0005 0.0282
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0075 0.0038 0.0037
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0003 0.0001
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0003 0.0003
Mycobacterium tuberculosis Soluble secreted antigen Mpt53 precursor 0.0024 0.0007 0.0004
Brugia malayi nuclear hormone receptor 0.0022 0.0006 0.0006
Mycobacterium ulcerans endonuclease IV 0.0084 0.0044 0.0041
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0017
Onchocerca volvulus Protein cycle homolog 0.004 0.0017 0.0179
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0422 0.0254 0.0544
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0005 0.0004
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.0006 0.0005
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0005 0.0004
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.0037 0.5338
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0002 0.0002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0003 0.0001
Schistosoma mansoni rab6-interacting 0.0022 0.0005 0.0004
Onchocerca volvulus 0.0058 0.0028 0.0338
Echinococcus multilocularis follistatin 0.0021 0.0005 0.0004
Onchocerca volvulus Cell death protein 3 homolog 0.0094 0.005 0.0671
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0063
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.0019 0.0036
Toxoplasma gondii exonuclease III APE 0.0021 0.0005 0.0006
Plasmodium falciparum 1-cys peroxiredoxin 0.0093 0.005 0.0103
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0028 0.0009 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0005 0.0005
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0084 0.0044 0.0044
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0005 0.0005
Echinococcus granulosus carbonyl reductase 1 0.0026 0.0008 0.0008
Echinococcus multilocularis multidrug resistance associated protein 4 0.0022 0.0005 0.0005
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0021 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0026 0.0008 0.0051
Brugia malayi hypothetical protein 0.0026 0.0008 0.0008
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Trypanosoma brucei trypanothione reductase 0.0052 0.0024 0.0047
Echinococcus multilocularis muscleblind protein 1 0.0164 0.0094 0.0093
Trypanosoma brucei short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0091 0.0048 0.7212
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0072 0.0036 0.0074
Schistosoma mansoni transcription factor btf3 0.0038 0.0016 0.0014
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.0026 0.0008 0.0012
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0003 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0075 0.0038 0.0038
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0018 0.2811
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0008 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.0021 0.0021
Schistosoma mansoni cpg binding protein 0.0033 0.0013 0.0011
Entamoeba histolytica hypothetical protein 0.0038 0.0016 0.1827
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0066 0.0033 0.0066
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0422 0.0254 0.0544
Onchocerca volvulus 0.0026 0.0008 0.0051
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0072 0.0036 0.0074
Echinococcus granulosus FTZ F1 alpha 0.0047 0.0021 0.002
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0026 0.0008 0.0012
Trypanosoma brucei DNA polymerase eta, putative 0.0065 0.0032 0.0064
Leishmania major oxidoreductase-like protein 0.0098 0.0053 0.0109
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0005 0.0004
Echinococcus granulosus dihydrofolate reductase 1.6105 1 1
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0003 0.0012
Loa Loa (eye worm) hypothetical protein 0.0487 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0017
Echinococcus multilocularis RUN 0.0022 0.0005 0.0005
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.0021 0.0242
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0049 0.0022 0.0044
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0005 0.0004
Mycobacterium ulcerans short-chain dehydrogenase 0.0026 0.0008 0.0005
Entamoeba histolytica ATP-binding cassette protein, putative 0.0028 0.0009 0.0801
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0084 0.0044 0.0042
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0011 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0003
Loa Loa (eye worm) dehydrogenase 0.0026 0.0008 0.0008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0005 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0002 0.0002
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0022 0.0005 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0063
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0028 0.0009 0.0009
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0027 0.0008 0.0013
Brugia malayi ABC transporter transmembrane region family protein 0.0028 0.0009 0.0009
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0003 0.0002
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0072 0.0036 0.0034
Schistosoma mansoni coup transcription factor 0.0047 0.0021 0.0019
Leishmania major hypothetical protein, conserved 0.0026 0.0008 0.0012
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.1107 0.068 0.0677
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0052 0.0024 0.0046
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0026 0.0008 0.0012
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.0021 0.0019
Trypanosoma brucei oxidoreductase-like protein 0.0098 0.0053 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0013 0.0011
Schistosoma mansoni rab6-interacting 0.0022 0.0005 0.0004
Echinococcus granulosus tar DNA binding protein 0.0139 0.0078 0.0077
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0015 0.0015
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0026 0.0008 0.0593
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Brugia malayi Dehydrogenases, short chain protein 2 0.0026 0.0008 0.0008
Trypanosoma brucei unspecified product 0.0026 0.0008 0.0011
Mycobacterium ulcerans short-chain type oxidoreductase 0.0026 0.0008 0.0005
Echinococcus multilocularis caspase 8 0.0049 0.0022 0.0021
Schistosoma mansoni retinoic acid receptor RXR 0.0155 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0004
Mycobacterium ulcerans carveol-like dehydrogenase 0.0026 0.0008 0.0005
Loa Loa (eye worm) glutaminase 2 0.0298 0.0177 0.0177
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0026 0.0008 0.0006
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Leishmania major short chain dehydrogenase/reductase, putative 0.0026 0.0008 0.0012
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0003 0.0012
Schistosoma mansoni carbonyl reductase 0.0026 0.0008 0.0007
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0005 0.0005
Onchocerca volvulus 0.0054 0.0026 0.0308
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0014
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0005 0.0005
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0072 0.0036 0.0075
Echinococcus granulosus bloom syndrome protein 0.005 0.0023 0.0022
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0005 0.0004
Echinococcus multilocularis transcription factor btf3 0.0038 0.0016 0.0015
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0021 0.0042
Mycobacterium ulcerans dihydrofolate reductase DfrA 1.6105 1 1
Echinococcus multilocularis tar DNA binding protein 0.0139 0.0078 0.0077
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0003
Schistosoma mansoni retinal dehydrogenase 0.0026 0.0008 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0072 0.0036 0.0036
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0118 0.0065 0.0064
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0027 0.0024
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0026 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Leishmania major hypothetical protein, conserved 0.0026 0.0008 0.0012
Plasmodium falciparum V-type K+-independent H+-translocating inorganic pyrophosphatase 0.0369 0.0221 0.0472
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0009
Brugia malayi Cell death protein 3 precursor 0.0094 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0449 0.0271 0.0269
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0005 0.0056
Echinococcus granulosus dnaJ subfamily B 0.0449 0.0271 0.027
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Giardia lamblia Hypothetical protein 0.0026 0.0008 0.0949
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0026 0.0008 0.0593
Trypanosoma brucei short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Brugia malayi Melibiase family protein 0.0075 0.0038 0.0038
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0026 0.0008 0.0593
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.0091 0.0089
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0027 0.0024
Echinococcus granulosus retinol dehydrogenase 11 0.0026 0.0008 0.0008
Mycobacterium ulcerans ketoacyl reductase 0.0026 0.0008 0.0005
Trypanosoma brucei metacaspase 0.0049 0.0022 0.0042
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0018 0.2291
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0005
Brugia malayi hypothetical protein 0.026 0.0153 0.0153
Echinococcus multilocularis GPCR, family 2 0.0017 0.0003 0.0002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.0021 0.002
Echinococcus granulosus lamin 0.003 0.001 0.001
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0072 0.0036 0.0074
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Plasmodium vivax SET domain protein, putative 0.0033 0.0013 0.0022
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0005 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0052 0.0024 0.0023
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0005 0.0066
Toxoplasma gondii redoxin domain-containing protein 0.0093 0.005 0.0104
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0041
Schistosoma mansoni multidrug resistance protein 0.0028 0.0009 0.0008
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0026 0.0008 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0006 0.0006
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0008 0.0005
Echinococcus granulosus steroid dehydrogenase 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Toxoplasma gondii oxidoreductase, putative 0.0026 0.0008 0.0014
Trypanosoma brucei unspecified product 0.0059 0.0028 0.0056
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0062 0.006
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0049 0.0022 0.0044
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0072 0.0036 0.0074
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0005 0.0004
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0092
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0026 0.0008 0.0012
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.001 0.0287
Plasmodium vivax steroid dehydrogenase, putative 0.0026 0.0008 0.0012
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0005 0.0005
Echinococcus multilocularis conserved hypothetical protein 0.0026 0.0008 0.0008
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0052 0.0024 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0005 0.0056
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0007
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0422 0.0254 0.0253
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0005 0.0006
Mycobacterium ulcerans short chain dehydrogenase 0.0098 0.0053 0.005
Mycobacterium tuberculosis Probable oxidoreductase 0.0026 0.0008 0.0005
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0026 0.0008 0.0005
Echinococcus granulosus survival motor neuron protein 1 0.026 0.0153 0.0153
Trichomonas vaginalis peroxiredoxin, putative 0.0024 0.0007 0.011
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0164 0.0094 0.0093
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0052 0.0024 0.0023
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0026 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.004 0.0017 0.0017
Onchocerca volvulus 0.003 0.001 0.008
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0042
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0021 0.0494
Trypanosoma cruzi DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Trichomonas vaginalis DNA helicase recq1, putative 0.005 0.0023 0.0541
Echinococcus granulosus apoptotic protease activating factor 1 0.0045 0.002 0.0019
Brugia malayi Isocitrate dehydrogenase 0.0052 0.0024 0.0024
Mycobacterium ulcerans short-chain dehydrogenase 0.0026 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0058 0.0028 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0003
Brugia malayi Reduced folate carrier family protein 0.0107 0.0058 0.0058
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.0021 0.0019
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0022 0.0042
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0005 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0026 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Onchocerca volvulus Folate transporter 1 homolog 0.0107 0.0058 0.0789
Brugia malayi glutathione reductase 0.0052 0.0024 0.0024
Echinococcus multilocularis carbonyl reductase 1 0.0026 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0009 0.0014
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.0006 0.0005
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0118 0.0065 0.0062
Schistosoma mansoni DNA helicase recq5 0.002 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0063
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0045
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0026 0.0008 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0006 0.0005
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0072 0.0036 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0003 0.0001
Echinococcus granulosus intermediate filament protein 0.003 0.001 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0003 0.0001
Echinococcus granulosus hypothetical protein 0.0026 0.0008 0.0008
Trichomonas vaginalis rotamase, putative 0.0035 0.0014 0.0302
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0017 0.0003 0.0002
Brugia malayi nuclear receptor NHR-67 0.0022 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.0021 0.0021
Giardia lamblia Short-chain dehydrogenase, putative 0.0026 0.0008 0.0949
Toxoplasma gondii melibiase subfamily protein 0.0113 0.0062 0.013
Giardia lamblia Reductase, putative 0.0026 0.0008 0.0949
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0005 0.0003
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0005 0.0005
Brugia malayi jmjC domain containing protein 0.0017 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0003
Echinococcus multilocularis musashi 0.003 0.001 0.001
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0128 0.0072 0.0071
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0118 0.0065 0.0064
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0062 0.006
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0011 0.002
Echinococcus multilocularis transient receptor potential cation channel 0.0026 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0006 0.0004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0013 0.0012
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Plasmodium falciparum thioredoxin reductase 0.0018 0.0003 0.0001
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0072 0.0036 0.0034
Trypanosoma cruzi vacuolar-type proton translocating pyrophosphatase 1 0.0369 0.0221 0.0472
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0072 0.0036 0.0034
Brugia malayi hypothetical protein 0.0615 0.0374 0.0374
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0005 0.0005
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0072 0.0036 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0007
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.0037 0.0036
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0006 0.0003
Onchocerca volvulus 0.0022 0.0005 0.0007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0257 0.0152 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0186 0.4927
Echinococcus multilocularis lamin 0.003 0.001 0.001
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0072 0.0036 0.528
Brugia malayi hypothetical protein 0.0028 0.0009 0.0009
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0026 0.0008 0.124
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0008 0.0011
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0078 0.0076
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.0006 0.0005
Echinococcus multilocularis folate receptor beta 0.0915 0.056 0.056
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Brugia malayi hypothetical protein 0.004 0.0017 0.0017
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0002 0.0002
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0026 0.0008 0.0008
Echinococcus granulosus phd:f box containing protein 0.0017 0.0002 0.0002
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0027 0.0008 0.0013
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0155 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0072 0.0036 0.0075
Leishmania major short chain dehydrogenase, putative 0.0026 0.0008 0.0012
Onchocerca volvulus Sepiapterin reductase homolog 0.0026 0.0008 0.0051
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0043
Brugia malayi hypothetical protein 0.0487 0.0294 0.0294
Loa Loa (eye worm) hypothetical protein 0.0151 0.0085 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0005 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0006 0.0004
Schistosoma mansoni survival motor neuron protein 0.0053 0.0025 0.0023
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0026 0.0008 0.0005
Onchocerca volvulus 0.0026 0.0008 0.0051
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0027 0.0026
Brugia malayi Retinol dehydrogenase 12 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0026 0.0008 0.0051
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Echinococcus multilocularis expressed protein 0.0036 0.0014 0.0014
Brugia malayi TAR-binding protein 0.0139 0.0078 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0022 0.0523
Schistosoma mansoni transcription factor LCR-F1 0.0118 0.0065 0.0063
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0002 0.0002
Plasmodium vivax glutathione reductase, putative 0.0052 0.0024 0.0047
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0014 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0066 0.0033 0.003
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0014 0.0014
Leishmania major folylpolyglutamate synthetase 0.0422 0.0254 0.0544
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0011 0.0089
Trypanosoma cruzi short chain dehydrogenase, putative 0.0026 0.0008 0.0012
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0006 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.0021 0.0021
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0014 0.0024
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0008 0.014
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0006 0.0005
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0007 0.0006
Entamoeba histolytica hypothetical protein 0.0021 0.0005 0.0041
Brugia malayi jmjC domain containing protein 0.0017 0.0002 0.0002
Schistosoma mansoni dihydrofolate reductase 1.6105 1 1
Brugia malayi steroid hormone receptor 0.0047 0.0021 0.0021
Echinococcus granulosus dna polymerase kappa 0.0066 0.0033 0.0032
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0011 0.0019
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0005 0.0005
Echinococcus multilocularis retinol dehydrogenase 11 0.0026 0.0008 0.0008
Schistosoma mansoni lipoxygenase 0.0061 0.0029 0.0028
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0005 0.0004
Echinococcus granulosus RUN 0.0022 0.0005 0.0005
Plasmodium vivax metacaspase 1, putative 0.0049 0.0022 0.0042
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0011 0.0021
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0026 0.0008 0.0012
Echinococcus multilocularis agrin 0.0021 0.0005 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0003 0.0001
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0004
Echinococcus multilocularis caspase 3 0.008 0.0041 0.0041
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Brugia malayi nuclear receptor NHR-88 0.0047 0.0021 0.0021
Echinococcus granulosus caspase 0.0128 0.0072 0.0071
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Brugia malayi hypothetical protein 0.0045 0.002 0.002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0003 0.0003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Entamoeba histolytica hypothetical protein 0.0118 0.0065 1
Toxoplasma gondii hypothetical protein 0.003 0.001 0.0018
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0018 0.0035
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0005 0.0003
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0004 0.0003
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0026 0.0008 0.0012
Brugia malayi jmjC domain containing protein 0.0066 0.0033 0.0033
Echinococcus multilocularis multidrug resistance associated protein 7 0.0028 0.0009 0.0009
Brugia malayi Probable ClpP-like protease 0.0086 0.0045 0.0045
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0021 0.004
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0026 0.0008 0.0051
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0006
Schistosoma mansoni DNA polymerase eta 0.0065 0.0032 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0005 0.0003
Leishmania major importin beta-1 subunit, putative 0.0026 0.0008 0.0011
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Schistosoma mansoni zinc finger protein 0.0022 0.0006 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0021 0.002
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0422 0.0254 0.0546
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Brugia malayi Dehydrogenases, short chain protein 30 0.0026 0.0008 0.0008
Echinococcus multilocularis dna polymerase kappa 0.0066 0.0033 0.0032
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0002 0.0002
Echinococcus granulosus importin subunit beta 1 0.0032 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0005 0.0063
Trypanosoma brucei DNA polymerase IV, putative 0.0066 0.0033 0.0066
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0072 0.0036 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0615 0.0374 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Schistosoma mansoni polycystin 1-related 0.0022 0.0005 0.0004
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0072 0.0036 0.7946
Brugia malayi hypothetical protein 0.0022 0.0005 0.0005
Trypanosoma cruzi short chain dehydrogenase, putative 0.0026 0.0008 0.0012
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.0021 0.002
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0026 0.0008 0.0012
Entamoeba histolytica hypothetical protein 0.0118 0.0065 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0017 0.0032
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0028 0.0009 0.0015
Onchocerca volvulus 0.0022 0.0005 0.0007
Brugia malayi conserved hypotetical protein 0.0022 0.0006 0.0006
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0072 0.0036 0.0074
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Giardia lamblia Hypothetical protein 0.0107 0.0058 1
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0026 0.0008 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0126 0.3318
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0078 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.0021 0.0021
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0005 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0003 0.0001
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0422 0.0254 0.6769
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.0006 0.0006
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0045 0.0094
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0033 0.0032
Trypanosoma brucei multidrug resistance protein E 0.0028 0.0009 0.0015
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0024 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0049 0.0022 0.0523
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0338 0.0202 0.0202
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Echinococcus granulosus carbonyl reductase 1 0.0026 0.0008 0.0008
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0011 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Echinococcus multilocularis isocitrate dehydrogenase 0.0052 0.0024 0.0023
Toxoplasma gondii oxidoreductase, putative 0.0026 0.0008 0.0014
Leishmania major pteridine reductase 1 0.17 0.1048 0.2264
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0005 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.0021 0.0021
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.004 0.0017 0.0017
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0045 0.0094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Echinococcus multilocularis carbonyl reductase 1 0.0026 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0371 0.0222 0.0221
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0026 0.0008 0.0593
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0019 0.0036
Entamoeba histolytica hypothetical protein 0.0026 0.0008 0.0517
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0072 0.0036 0.0034
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0005 0.0005
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.0021 0.0019
Leishmania major dihydrofolate reductase-thymidylate synthase 0.7452 0.4623 1
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Echinococcus granulosus transcription factor btf3 0.0038 0.0016 0.0015
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0085 0.0045 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.0021 0.0021
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0072 0.0036 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.0021 0.0021
Loa Loa (eye worm) retinol dehydrogenase 12 0.0072 0.0036 0.0036
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0014 0.1513
Trichomonas vaginalis steroid dehydrogenase, putative 0.0026 0.0008 0.0152
Schistosoma mansoni hypothetical protein 0.0338 0.0202 0.02
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0026 0.0008 0.0152
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0013 0.0012
Onchocerca volvulus 0.0031 0.0011 0.0089
Trypanosoma cruzi multidrug resistance protein E, putative 0.0028 0.0009 0.0015
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0026 0.0008 0.0007
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0005 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.0021 0.0021
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0015 0.0015
Brugia malayi FolC bifunctional protein 0.0422 0.0254 0.0254
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0005 0.0007
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0026 0.0008 0.0008
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Schistosoma mansoni nuclear receptor 0.0022 0.0006 0.0004
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0002 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0119 0.3133
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0034 0.0013 0.0022
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.0134 0.0134
Plasmodium falciparum importin beta, putative 0.0032 0.0011 0.0019
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0005 0.0004
Toxoplasma gondii isocitrate dehydrogenase 0.0052 0.0024 0.0048
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0026 0.0008 0.0012
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0026 0.0008 0.0051
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0011 0.0011
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0052 0.0024 0.0046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Brugia malayi nuclear receptor RXR 0.0025 0.0007 0.0007
Mycobacterium ulcerans DNA polymerase IV 0.0066 0.0033 0.003
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0007 0.0007
Echinococcus granulosus expressed protein 0.041 0.0247 0.0246
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0005
Schistosoma mansoni multidrug resistance protein 0.0028 0.0009 0.0008
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0005 0.0005
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0013 0.0024
Loa Loa (eye worm) thymidylate synthase 0.1107 0.068 0.068
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0005 0.0004
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0026 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0005 0.0003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0021 0.0021
Onchocerca volvulus 0.0031 0.0011 0.0089
Leishmania major short chain dehydrogenase, putative 0.0026 0.0008 0.0012
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0065 0.0032 0.0031
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.0021 0.0242
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0005 0.0005
Giardia lamblia Multidrug resistance-associated protein 1 0.0028 0.0009 0.1177
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0008 0.0154
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0028 0.0056
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0005 0.0006
Echinococcus granulosus multidrug resistance associated protein 1 0.0028 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.0021 0.0021
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0014 0.0026
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0002
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0015 0.0013
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0422 0.0254 0.0544
Loa Loa (eye worm) agrin synaptic family protein 0.0021 0.0005 0.0004
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0033 0.0031
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0422 0.0254 0.3691
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0007
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0027 0.0008 0.0013
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.0006 0.0005
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0015 0.0013
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Trypanosoma brucei pteridine reductase 1 0.1674 0.1032 0.2228
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0026 0.0008 0.0005
Schistosoma mansoni hypothetical protein 0.0053 0.0025 0.0023
Onchocerca volvulus 0.0026 0.0008 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Loa Loa (eye worm) glutathione reductase 0.0052 0.0024 0.0024
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0065 0.0032 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.0021 0.0021
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.0186 0.0186
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Brugia malayi dehydrogenases, short chain protein 2 0.0026 0.0008 0.0008
Trypanosoma brucei metacaspase MCA2 0.0049 0.0022 0.0042
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0045 0.0045
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0113 0.0062 0.006
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.001 0.001
Plasmodium falciparum enoyl-acyl carrier reductase 0.0072 0.0036 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0006 0.0005
Loa Loa (eye worm) oxidoreductase 0.0072 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0126 0.3318
Toxoplasma gondii protease inhibitor PI2 0.0021 0.0005 0.0007
Leishmania major ABC-thiol transporter 0.0028 0.0009 0.0015
Echinococcus granulosus microtubule associated protein 2 0.0758 0.0463 0.0462
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0005 0.0005
Loa Loa (eye worm) RecQ helicase 0.005 0.0023 0.0022
Giardia lamblia ABC transporter, putative 0.0028 0.0009 0.1177
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0052 0.0024 0.0021
Giardia lamblia Multidrug resistance-associated protein 1 0.0028 0.0009 0.1151
Trypanosoma brucei transcription factor BTF3, putative 0.0038 0.0016 0.0028
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0045 1
Brugia malayi follicle stimulating hormone receptor 0.0257 0.0152 0.0152
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0005 0.0004
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0002 0.0001
Onchocerca volvulus 0.0047 0.0021 0.0242
Trypanosoma cruzi DNA polymerase kappa, putative 0.0066 0.0033 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0007
Leishmania major DNA polymerase eta, putative 0.0065 0.0032 0.0064
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0085 0.0045 0.0043
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0098 0.0053 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0008 0.0012
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0005 0.0005
Toxoplasma gondii endonuclease IV APN 0.0084 0.0044 0.0092
Onchocerca volvulus 0.0026 0.0008 0.0051
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0118 0.0065 0.0063
Toxoplasma gondii hypothetical protein 0.0225 0.0132 0.0281
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.001 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0021 0.0021
Echinococcus granulosus WW domain containing oxidoreductase 0.0026 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0065 0.0032 0.0032
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0026 0.0008 0.0008
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0028 0.0009 0.0015
Trypanosoma cruzi metacaspase, putative 0.0049 0.0022 0.0042
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 1.6105 1 1
Brugia malayi polk-prov protein 0.0041 0.0017 0.0017
Echinococcus multilocularis lysine specific demethylase 5A 0.0065 0.0032 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0186 0.4927
Leishmania major hypothetical protein, conserved 0.0026 0.0008 0.0012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.0021 0.0019
Echinococcus granulosus follistatin 0.0021 0.0005 0.0004
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0006 0.0011
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0026 0.0008 0.0012
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0026 0.0008 0.0006
Trypanosoma brucei short-chain dehydrogenase, putative 0.0026 0.0008 0.0012
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0084 0.0044 0.0041
Trypanosoma cruzi Vacuolar proton pyrophosphatase 1, putative 0.0369 0.0221 0.0472
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Toxoplasma gondii V-type H(+)-translocating pyrophosphatase VP1 0.0369 0.0221 0.0474
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.001
Brugia malayi beta-NAC-like protein 0.0038 0.0016 0.0016
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0026 0.0008 0.0152
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.0006 0.0006
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0028 0.0009 0.0015
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0031 0.0011 0.001
Loa Loa (eye worm) oxidoreductase 0.0026 0.0008 0.0008
Brugia malayi Thioredoxin reductase 0.0052 0.0024 0.0024
Entamoeba histolytica transcription factor BTF3, putative 0.0038 0.0016 0.1827
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0013 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0005 0.0005
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0049 0.0022 0.002
Mycobacterium ulcerans thymidylate synthase 0.1107 0.068 0.0677
Loa Loa (eye worm) hypothetical protein 0.0022 0.0005 0.0005
Onchocerca volvulus 0.003 0.001 0.008
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0009 0.0014
Mycobacterium leprae POSSIBLE MEMBRANE-ANCHORED THIOREDOXIN-LIKE PROTEIN (THIOL-DISULFIDE INTERCHANGE RELATED PROTEIN) 0.0024 0.0007 0.0004
Echinococcus granulosus caspase 8 0.0049 0.0022 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0186 0.4927
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0072 0.0036 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0022 0.0523
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0098 0.0053 0.005
Schistosoma mansoni intermediate filament proteins 0.003 0.001 0.0009
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0058 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0107 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Mycobacterium ulcerans epimerase 0.0022 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0348 0.0208 0.0208
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.0021 0.0019
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0008 0.0593
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0008 0.0012
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0026 0.0008 0.0005
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.0422 0.0254 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0008 0.0012
Mycobacterium ulcerans short chain dehydrogenase 0.0026 0.0008 0.0005
Toxoplasma gondii carbonyl reductase 1, putative 0.0026 0.0008 0.0014
Echinococcus multilocularis Protein lozenge 0.0061 0.003 0.0029
Loa Loa (eye worm) multidrug resistance-associated protein 0.0022 0.0005 0.0005
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0119 0.1691
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0028 0.0009 0.0801
Brugia malayi nuclear receptor RXR 0.0022 0.0006 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0052 0.0024 0.0046
Mycobacterium ulcerans oxidoreductase 0.0026 0.0008 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0186 0.4927
Leishmania major quinonoid dihydropteridine reductase 0.0026 0.0008 0.0012
Brugia malayi PXA domain containing protein 0.0021 0.0005 0.0005
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0033 0.0031
Onchocerca volvulus 0.0026 0.0008 0.0051
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0003 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0013 0.0011
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0026 0.0008 0.0006
Echinococcus multilocularis oxidoreductase 0.0026 0.0008 0.0008
Trichomonas vaginalis peroxiredoxin, putative 0.0024 0.0007 0.011
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0026 0.0026
Schistosoma mansoni short chain dehydrogenase 0.0026 0.0008 0.0007
Brugia malayi hypothetical protein 0.0134 0.0075 0.0075
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0007 0.0007
Plasmodium vivax V-type H(+)-translocating pyrophosphatase, putative 0.0369 0.0221 0.0472
Mycobacterium ulcerans short chain dehydrogenase 0.0072 0.0036 0.0034
Echinococcus multilocularis tumor protein p63 0.0371 0.0222 0.0222
Schistosoma mansoni DNA helicase recq1 0.002 0.0005 0.0003
Plasmodium falciparum glutathione reductase 0.0018 0.0003 0.0001
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.0006 0.0005
Onchocerca volvulus 0.1107 0.068 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0026 0.0008 0.0005
Giardia lamblia MRP-like ABC transporter 0.0028 0.0009 0.1177
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0015 0.0012
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0026 0.0008 0.0012
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0085 0.0045 0.0042
Schistosoma mansoni multidrug resistance protein 0.0028 0.0009 0.0008
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.0271 0.027
Onchocerca volvulus 0.0107 0.0058 0.0789
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0098 0.0053 0.0109
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0026 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.0021 0.0021
Schistosoma mansoni glutaminase 0.0298 0.0177 0.0176
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0002 0.0001
Mycobacterium tuberculosis Probable conserved lipoprotein DsbF 0.0024 0.0007 0.0004
Trypanosoma cruzi metacaspase, putative 0.0049 0.0022 0.0042
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0005 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0186 0.4927
Echinococcus granulosus aryl hydrocarbon receptor 0.0058 0.0028 0.0027
Brugia malayi dehydrogenases, short chain protein 9 0.0026 0.0008 0.0008
Leishmania major trypanothione reductase 0.0052 0.0024 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0002 0.0002
Schistosoma mansoni steroid dehydrogenase 0.0026 0.0008 0.0007
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0026 0.0008 0.0005
Onchocerca volvulus 0.0107 0.0058 0.0789
Onchocerca volvulus 0.0026 0.0008 0.0051
Plasmodium falciparum thioredoxin reductase 0.0052 0.0024 0.0047
Loa Loa (eye worm) dihydrofolate reductase 1.6105 1 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0003 0.0001
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0026 0.0008 0.0152
Brugia malayi multidrug resistance related protein 1 0.0028 0.0009 0.0009
Brugia malayi nuclear receptor NHR-88 0.0022 0.0006 0.0006
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0003 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0139 0.0078 0.0076
Treponema pallidum thioredoxin 0.0024 0.0007 0.0146
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0002 0.0002
Schistosoma mansoni caspase-7 (C14 family) 0.0128 0.0072 0.007
Schistosoma mansoni agrin 0.0021 0.0005 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0016 0.0353

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) 0 M Compound was tested for inhibitory activity against glucocerebroside synthase at dose 1.0E-4; No inhibition ChEMBL. No reference
IC50 (binding) 0 M Compound was tested for inhibitory activity against alpha-glucosidase; Not tested ChEMBL. No reference
IC50 (binding) = 0.0000003 M Compound was tested for inhibitory activity against beta-glucocerebrosidase. ChEMBL. No reference
IC50 (binding) = 0.0000003 M Compound was tested for inhibitory activity against beta-glucocerebrosidase. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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