Detailed information for compound 30512

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 559.591 | Formula: C28H38N3O7P
  • H donors: 4 H acceptors: 6 LogP: 2.79 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)N[C@H](C(=O)N[C@H]1CCCCN(C1=O)Cc1ccc(cc1)C(C)(C)C)Cc1ccc(cc1)OP(=O)(O)O
  • InChi: 1S/C28H38N3O7P/c1-19(32)29-25(17-20-10-14-23(15-11-20)38-39(35,36)37)26(33)30-24-7-5-6-16-31(27(24)34)18-21-8-12-22(13-9-21)28(2,3)4/h8-15,24-25H,5-7,16-18H2,1-4H3,(H,29,32)(H,30,33)(H2,35,36,37)/t24-,25-/m0/s1
  • InChiKey: KIFQSOOTOUCFGO-DQEYMECFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SRC proto-oncogene, non-receptor tyrosine kinase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) TK protein kinase Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Srms Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Src64B Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine kinase Get druggable targets OG5_127750 All targets in OG5_127750
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Lyn Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Src42A Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma japonicum Proto-oncogene tyrosine-protein kinase FYN, putative Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Brugia malayi SRC-1 Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Src42A Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase HCK Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Fgr Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Src64B Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Src42A Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma japonicum ko:K08892 fyn-related kinase, putative Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Blk Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma japonicum Proto-oncogene tyrosine-protein kinase FYN, putative Get druggable targets OG5_127750 All targets in OG5_127750
Brugia malayi protein-tyrosine kinase Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma japonicum ko:K05703 proto-oncogene tyrosine-protein kinase Fyn, putative Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Blk Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase HCK Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma japonicum Proto-oncogene tyrosine-protein kinase Yrk, putative Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus multilocularis tyrosine protein kinase Fyn Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus tyrosine protein kinase Src42A Get druggable targets OG5_127750 All targets in OG5_127750
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK Get druggable targets OG5_127750 All targets in OG5_127750
Loa Loa (eye worm) TK protein kinase Get druggable targets OG5_127750 All targets in OG5_127750
Loa Loa (eye worm) SRC-1 Get druggable targets OG5_127750 All targets in OG5_127750
Schistosoma japonicum Proto-oncogene tyrosine-protein kinase FGR, putative Get druggable targets OG5_127750 All targets in OG5_127750
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0118 0.0115
Trypanosoma cruzi histone deacetylase, putative 0.0103 0.0413 0.0608
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0118 0.0113
Giardia lamblia UPL-1 0.0205 0.0988 0.521
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Trichomonas vaginalis shk1 kinase-binding protein, putative 0.0041 0.0057 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Onchocerca volvulus 0.0132 0.0575 0.0565
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0664 0.36 0.3594
Schistosoma mansoni tyrosine kinase 0.0045 0.0084 0.008
Echinococcus granulosus protein arginine N methyltransferase 8 0.0034 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0159 0.0731 0.1086
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni biogenic amine receptor 0.0051 0.0118 0.0115
Schistosoma mansoni uridine phosphorylase 0.0205 0.0988 0.104
Trypanosoma brucei histone deacetylase, putative 0.0103 0.0413 0.054
Echinococcus multilocularis purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0034 0.0021 0.0013
Trypanosoma brucei transcription elongation factor s-II, putative 0.0132 0.0575 0.0785
Brugia malayi RE15519p 0.0051 0.0118 0.0125
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0034 0.0021 0.0013
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0118 0.0125
Echinococcus granulosus tyrosine protein kinase Blk 0.0041 0.0059 0.0062
Trypanosoma cruzi histone deacetylase 1, putative 0.0362 0.1887 0.2822
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0118 0.0125
Echinococcus multilocularis serotonin receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0084 0.0089
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0205 0.0988 0.2727
Plasmodium vivax spermidine synthase, putative 0.1202 0.6662 1
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0159 0.0731 0.0776
Brugia malayi Skb1 methyltransferase family protein 0.0064 0.0187 0.0198
Trypanosoma cruzi spermidine synthase, putative 0.1202 0.6662 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0045 0.0084 0.0089
Echinococcus granulosus neuropeptide receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) CXXC zinc finger family protein 0.0383 0.2004 0.2116
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0118 0.0125
Giardia lamblia Histone deacetylase 0.0362 0.1887 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0118 0.0113
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0118 0.0125
Echinococcus granulosus serotonin receptor 0.0051 0.0118 0.0125
Trypanosoma cruzi histone deacetylase, putative 0.0103 0.0413 0.0608
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0118 0.0125
Brugia malayi Histone deacetylase family protein 0.0103 0.0413 0.0439
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0205 0.0988 0.1472
Plasmodium vivax histone deacetylase 1, putative 0.0362 0.1887 0.282
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.0988 0.098
Leishmania major nucleoside phosphorylase-like protein 0.0205 0.0988 0.1472
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0034 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Entamoeba histolytica hypothetical protein 0.0205 0.0988 0.2727
Leishmania major methylthioadenosine phosphorylase, putative 0.1105 0.6106 0.9164
Echinococcus granulosus neuropeptide receptor 0.0051 0.0118 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0242 0.1201 0.1274
Schistosoma mansoni SET domain protein 0.0149 0.0675 0.0707
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0011 0.0004
Onchocerca volvulus 0.0405 0.213 0.2121
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.1887 0.1879
Trypanosoma cruzi histone deacetylase, putative 0.0103 0.0413 0.0608
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.0132 0.0575 0.0851
Echinococcus multilocularis PWWP domain containing protein 2A 0.0132 0.0575 0.061
Schistosoma mansoni histone deacetylase hda2 0.0103 0.0413 0.0429
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.1105 0.6106 0.9158
Echinococcus granulosus histone deacetylase 8 0.0103 0.0413 0.0439
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0362 0.1887 0.1879
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0091 0.0097
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.1887 0.1879
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0948 0.5214 1
Toxoplasma gondii histone deacetylase HDAC2 0.0362 0.1887 0.387
Loa Loa (eye worm) hypothetical protein 0.1008 0.5555 0.5887
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.1887 0.1879
Plasmodium vivax SET domain protein, putative 0.0175 0.0821 0.1218
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0617 0.3335 0.4997
Echinococcus multilocularis histone deacetylase 6 0.0103 0.0413 0.0439
Toxoplasma gondii hypothetical protein 0.0132 0.0575 0.1167
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.0095 0.0365 0.0532
Leishmania major arginine N-methyltransferase, type II, putative;with=GeneDB:Tb927.10.640 0.0041 0.0057 0.0072
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0118 0.0113
Plasmodium vivax adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative 0.0664 0.36 0.5396
Echinococcus multilocularis purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Echinococcus multilocularis tyrosine protein kinase HCK 0.0036 0.0033 0.0035
Toxoplasma gondii histone arginine methyltransferase PRMT5 0.0064 0.0187 0.0366
Entamoeba histolytica histone deacetylase, putative 0.0362 0.1887 0.5228
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0214 0.1045 0.1557
Loa Loa (eye worm) uridine phosphorylase 0.0205 0.0988 0.1038
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0118 0.0125
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0061 0.0064
Schistosoma mansoni histone J3 methyltransferase 0.1689 0.9429 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0118 0.0115
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0118 0.0125
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0118 0.0115
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0118 0.0125
Brugia malayi GATA zinc finger family protein 0.0047 0.009 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Brugia malayi PHD-finger family protein 0.0033 0.0011 0.0012
Onchocerca volvulus 0.0051 0.0118 0.0106
Schistosoma mansoni methylthioadenosine phosphorylase 0.1105 0.6106 0.6473
Echinococcus granulosus histone lysine n methyltransferase setb1 0.0038 0.0041 0.0044
Entamoeba histolytica hypothetical protein 0.0132 0.0575 0.1576
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0084 0.0089
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0886 0.4861 0.7292
Trypanosoma cruzi Histone methylation protein DOT1, putative 0.0214 0.1045 0.1557
Onchocerca volvulus 0.0051 0.0118 0.0106
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.0084
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0045 0.0084 0.0089
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0159 0.0731 0.1086
Entamoeba histolytica protein kinase, putative 0.0036 0.0033 0.0066
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Treponema pallidum uridine phosphorylase (udp) 0.0205 0.0988 0.5
Chlamydia trachomatis AMP nucleosidase 0.0205 0.0988 0.5
Loa Loa (eye worm) SET domain-containing protein 0.0321 0.1649 0.1739
Schistosoma mansoni biogenic amine receptor 0.0051 0.0118 0.0115
Schistosoma mansoni bromo adjacent homology domain containing 0.0047 0.009 0.0086
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0034 0.0021 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0118 0.0125
Echinococcus granulosus histone deacetylase 6 0.0103 0.0413 0.0439
Echinococcus multilocularis cpg binding protein 0.0385 0.2014 0.2136
Schistosoma mansoni hypothetical protein 0.0051 0.0118 0.0115
Trichomonas vaginalis CDC6, putative 0.0047 0.009 0.0081
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0118 0.0125
Brugia malayi Protein arginine N-methyltransferase 0.0159 0.0731 0.0776
Onchocerca volvulus 0.0051 0.0118 0.0106
Brugia malayi SET domain containing protein 0.0321 0.1649 0.1748
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.0945 0.5199 0.5514
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0159 0.0731 0.1086
Brugia malayi SET domain containing protein 0.0064 0.019 0.0201
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.1008 0.5555 0.5887
Plasmodium vivax histone deacetylase, putative 0.0103 0.0413 0.0605
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0118 0.0113
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Loa Loa (eye worm) adenosylhomocysteinase 0.0664 0.36 0.3811
Schistosoma mansoni myosin xvIII 0.0051 0.0118 0.0115
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni methylthioadenosine phosphorylase 0.1105 0.6106 0.6473
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni opsin-like receptor 0.0051 0.0118 0.0115
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Trypanosoma brucei histone-lysine n-methyltransferase 0.0214 0.1045 0.1496
Schistosoma mansoni neuropeptide receptor 0.0051 0.0118 0.0115
Schistosoma mansoni hypothetical protein 0.0051 0.0118 0.0115
Onchocerca volvulus 0.0296 0.1508 0.1498
Loa Loa (eye worm) hypothetical protein 0.0056 0.0144 0.0141
Echinococcus granulosus peregrin 0.0165 0.0761 0.0807
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0118 0.0125
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0045 0.0084 0.0089
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0047 0.009 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus granulosus microtubule associated protein 2 0.0778 0.425 0.4507
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0034 0.0021 0.0012
Brugia malayi hypothetical protein 0.0067 0.0205 0.0217
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0118 0.0125
Echinococcus multilocularis histone deacetylase 6 0.0103 0.0413 0.0439
Brugia malayi Dopamine receptor 0.0051 0.0118 0.0125
Echinococcus granulosus tyrosine kinase 0.0041 0.0059 0.0062
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0118 0.0115
Schistosoma mansoni opsin-like receptor 0.0051 0.0118 0.0115
Leishmania major hypothetical protein, conserved 0.0214 0.1045 0.1557
Brugia malayi hypothetical protein 0.0132 0.0575 0.061
Loa Loa (eye worm) hypothetical protein 0.0077 0.0264 0.0269
Schistosoma mansoni tyrosine kinase 0.0045 0.0084 0.008
Echinococcus multilocularis adenosylhomocysteinase 0.0664 0.36 0.3818
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0084 0.0089
Trypanosoma cruzi spermidine synthase, putative 0.1202 0.6662 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.0041 0.0059 0.0062
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0011 0.0002
Schistosoma mansoni protein arginine n-methyltransferase 0.0163 0.0752 0.0789
Onchocerca volvulus 0.0051 0.0118 0.0106
Onchocerca volvulus 0.0051 0.0118 0.0106
Toxoplasma gondii histone deacetylase HDAC1 0.0103 0.0413 0.0833
Brugia malayi histone deacetylase 11 0.0103 0.0413 0.0439
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0403 0.2118 0.2239
Echinococcus granulosus geminin 0.019 0.0905 0.096
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0061 0.0055
Echinococcus multilocularis PWWP domain containing protein 2A 0.0132 0.0575 0.061
Echinococcus granulosus metastasis associated protein MTA1 0.0047 0.009 0.0095
Plasmodium falciparum histone deacetylase 1 0.0362 0.1887 0.282
Echinococcus multilocularis neuropeptide receptor A26 0.0051 0.0118 0.0125
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0362 0.1887 0.1879
Echinococcus granulosus allatostatin A receptor 0.0051 0.0118 0.0125
Brugia malayi GnHR receptor homolog 0.0051 0.0118 0.0125
Echinococcus granulosus histone deacetylase 6 0.0103 0.0413 0.0439
Entamoeba histolytica hypothetical protein 0.0067 0.0205 0.0545
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0118 0.0125
Schistosoma mansoni hypothetical protein 0.019 0.0905 0.0951
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0047 0.009 0.0086
Echinococcus multilocularis hepatoma derived growth factor protein 0.0132 0.0575 0.061
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0118 0.0125
Trypanosoma cruzi histone deacetylase, putative 0.0103 0.0413 0.0608
Trypanosoma cruzi Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0214 0.1045 0.1557
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.0052 0.0055
Brugia malayi jmjC domain containing protein 0.0041 0.0061 0.0064
Brugia malayi G protein-coupled receptor 0.0051 0.0118 0.0125
Echinococcus granulosus protein arginine methyltransferase 0.0034 0.0021 0.0022
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Trypanosoma cruzi histone deacetylase 1, putative 0.0362 0.1887 0.2822
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0197 0.0947 0.1005
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.09 0.4943 0.936
Plasmodium falciparum purine nucleoside phosphorylase 0.0205 0.0988 0.1469
Echinococcus granulosus somatostatin receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0118 0.0125
Echinococcus granulosus histone deacetylase 3 0.0362 0.1887 0.2001
Loa Loa (eye worm) hypothetical protein 0.0242 0.1201 0.1263
Brugia malayi polybromodomain protein 0.0047 0.009 0.0095
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0067 0.0205 0.0545
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0118 0.0125
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0118 0.0115
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0205 0.0988 0.1472
Entamoeba histolytica adenosylhomocysteinase, putative 0.0664 0.36 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0045 0.0084 0.0089
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.1105 0.6106 0.6472
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0118 0.0106
Schistosoma mansoni cpg binding protein 0.0383 0.2004 0.2117
Loa Loa (eye worm) hypothetical protein 0.0067 0.0205 0.0205
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0205 0.0988 0.2727
Echinococcus granulosus g protein coupled receptor 0.0051 0.0118 0.0125
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0205 0.0988 0.2727
Schistosoma mansoni hypothetical protein 0.0051 0.0118 0.0115
Brugia malayi NNMT/PNMT/TEMT family protein 0.1008 0.5555 0.5892
Toxoplasma gondii histone deacetylase HDAC5 0.0103 0.0413 0.0833
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Leishmania major histone-lysine N-methyltransferase, putative 0.0214 0.1045 0.1557
Schistosoma mansoni hypothetical protein 0.0132 0.0575 0.0601
Toxoplasma gondii S-Adenosyl homocysteine hydrolase 0.0664 0.36 0.7401
Onchocerca volvulus 0.0143 0.0639 0.0628
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.005 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0362 0.1887 0.1991
Echinococcus granulosus histone h3 methyltransferase 0.1689 0.9429 1
Schistosoma mansoni purine nucleoside phosphorylase 0.0205 0.0988 0.104
Toxoplasma gondii hypothetical protein 0.0214 0.1045 0.2134
Echinococcus granulosus hypothetical protein 0.0051 0.0118 0.0125
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.0945 0.5199 0.7784
Schistosoma mansoni neuropeptide receptor 0.0051 0.0118 0.0115
Leishmania major histone deacetylase, putative 0.0103 0.0413 0.0608
Brugia malayi G-protein coupled receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0118 0.0125
Brugia malayi uridine phosphorylase family protein 0.0205 0.0988 0.1048
Trypanosoma cruzi arginine N-methyltransferase, type II, putative 0.0041 0.0057 0.0072
Echinococcus granulosus tyrosine protein kinase HCK 0.0036 0.0033 0.0035
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0209 0.021
Echinococcus granulosus adenosylhomocysteinase 0.0664 0.36 0.3818
Loa Loa (eye worm) hypothetical protein 0.0121 0.0512 0.0532
Echinococcus granulosus arginine glutamic acid dipeptide RE repeats 0.0047 0.009 0.0095
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0011 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0084 0.0089
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0118 0.0125
Schistosoma mansoni opsin-like receptor 0.0051 0.0118 0.0115
Trypanosoma cruzi hypothetical protein, conserved 0.0132 0.0575 0.0851
Brugia malayi neuropeptide F receptor 0.0051 0.0118 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0118 0.0125
Echinococcus granulosus hepatoma derived growth factor protein 0.0132 0.0575 0.061
Schistosoma mansoni hepatoma derived growth factor 0.0132 0.0575 0.0601
Echinococcus granulosus PWWP domain containing protein 2A 0.0132 0.0575 0.061
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0047 0.009 0.0086
Brugia malayi S-adenosylmethionine decarboxylase proenzyme 0.0945 0.5199 0.5514
Loa Loa (eye worm) hypothetical protein 0.0403 0.2118 0.2237
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0617 0.3335 0.353
Toxoplasma gondii phosphorylase family protein 0.0205 0.0988 0.2018
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0945 0.5199 0.7784
Schistosoma mansoni shk1 kinase-binding protein 0.0064 0.0187 0.0188
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0163 0.0752 0.0798
Toxoplasma gondii Purine nucleoside phosphorylase 0.0205 0.0988 0.2018
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Echinococcus granulosus histone deacetylase 7 0.0103 0.0413 0.0439
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni enhancer of zeste ezh 0.0321 0.1649 0.174
Echinococcus multilocularis metastasis associated protein 1 (mta1) 0.0047 0.009 0.0095
Loa Loa (eye worm) hypothetical protein 0.0405 0.213 0.225
Echinococcus multilocularis histone deacetylase 6 0.0103 0.0413 0.0439
Brugia malayi Pre-SET motif family protein 0.163 0.9094 0.9645
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0242 0.1201 0.1265
Brugia malayi hypothetical protein 0.0229 0.1128 0.1197
Plasmodium vivax histone deacetylase, putative 0.0103 0.0413 0.0605
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0118 0.0115
Brugia malayi Histone deacetylase family protein 0.0103 0.0413 0.0439
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus protein arginine N methyltransferase 7 0.0159 0.0731 0.0776
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0067 0.0205 0.0294
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0118 0.0125
Brugia malayi Serotonin receptor 0.0051 0.0118 0.0125
Onchocerca volvulus 0.0051 0.0118 0.0106
Brugia malayi histone deacetylase 3 (HD3) 0.0362 0.1887 0.2001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0118 0.0125
Loa Loa (eye worm) histone deacetylase 0.0103 0.0413 0.0427
Schistosoma mansoni cpg binding protein 0.0385 0.2014 0.2128
Schistosoma mansoni amine GPCR 0.0051 0.0118 0.0115
Schistosoma mansoni amine GPCR 0.0051 0.0118 0.0115
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Plasmodium falciparum adenosylhomocysteinase 0.0664 0.36 0.5396
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0118 0.0125
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0045 0.0084 0.0089
Echinococcus multilocularis purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0664 0.36 0.5398
Brugia malayi Dopamine receptor protein 2 0.0051 0.0118 0.0125
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0118 0.0106
Echinococcus granulosus protein arginine N methyltransferase 5 0.0064 0.0187 0.0198
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0175 0.0821 0.0871
Loa Loa (eye worm) hypothetical protein 0.0103 0.0413 0.0427
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0118 0.0125
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0045 0.0084 0.0089
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0205 0.0988 0.521
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0118 0.0125
Echinococcus granulosus histone lysine N methyltransferase Ez 0.0321 0.1649 0.1748
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.1128 0.1197
Echinococcus granulosus PWWP domain containing protein 2A 0.0132 0.0575 0.061
Echinococcus granulosus histone lysine n methyltransferase suv420h1 0.0154 0.07 0.0743
Echinococcus multilocularis histone deacetylase 0.0103 0.0413 0.0439
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Schistosoma mansoni histone deacetylase 4 5 0.0103 0.0413 0.0429
Onchocerca volvulus 0.0051 0.0118 0.0106
Schistosoma mansoni hypothetical protein 0.019 0.0905 0.0951
Echinococcus granulosus methylthioadenosine phosphorylase 0.1105 0.6106 0.6476
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0118 0.0115
Onchocerca volvulus 0.0051 0.0118 0.0106
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.0945 0.5199 0.5508
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0084 0.0089
Schistosoma mansoni polybromo-1 0.0047 0.009 0.0086
Trypanosoma brucei histone deacetylase 3 0.0103 0.0413 0.054
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0107 0.0434 0.046
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0118 0.0113
Onchocerca volvulus 0.0132 0.0575 0.0565
Schistosoma mansoni amine GPCR 0.0051 0.0118 0.0115
Echinococcus granulosus orexin receptor type 2 0.0051 0.0118 0.0125
Onchocerca volvulus 0.0383 0.2004 0.1995
Echinococcus multilocularis spermidine synthase 0.1202 0.6662 0.7066
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) histone deacetylase 3 0.0362 0.1887 0.1991
Echinococcus granulosus metastasis associated protein 1 mta1 0.0047 0.009 0.0095
Brugia malayi follicle stimulating hormone receptor 0.0051 0.0118 0.0125
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.1887 0.1879
Schistosoma mansoni hypothetical protein 0.0047 0.009 0.0086
Brugia malayi Bromodomain containing protein 0.0033 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.1008 0.5555 0.5887
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0205 0.0988 0.1472
Brugia malayi SET domain containing protein 0.0137 0.0602 0.0638
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0205 0.0988 0.098
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Onchocerca volvulus 0.0051 0.0118 0.0106
Schistosoma mansoni suppressor of variegation 4-20-related 0.0154 0.07 0.0734
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0118 0.0125
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.1105 0.6106 0.9164
Echinococcus multilocularis histone deacetylase 1 0.0362 0.1887 0.2001
Echinococcus multilocularis polybromo 1 0.0047 0.009 0.0095
Plasmodium vivax protein arginine N-methyltransferase 5, putative 0.0064 0.0187 0.0264
Onchocerca volvulus 0.0051 0.0118 0.0106
Leishmania major S-adenosylhomocysteine hydrolase 0.0664 0.36 0.5398
Schistosoma mansoni histone deacetylase 0.0362 0.1887 0.1993
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0051 0.0118 0.0113
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0118 0.0125
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0175 0.0821 0.1673
Echinococcus multilocularis histone deacetylase 8 0.0103 0.0413 0.0439
Loa Loa (eye worm) histone deacetylase 1 0.0362 0.1887 0.1991
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0118 0.0125
Brugia malayi CXXC zinc finger family protein 0.0383 0.2004 0.2125
Echinococcus multilocularis methylthioadenosine phosphorylase 0.1105 0.6106 0.6476
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0118 0.0113
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0127 0.0547 0.0569
Loa Loa (eye worm) hypothetical protein 0.0048 0.01 0.0095
Toxoplasma gondii histone deacetylase HDAC4 0.0103 0.0413 0.0833
Echinococcus multilocularis peregrin 0.0165 0.0761 0.0807
Brugia malayi putative neuropeptide receptor 0.0051 0.0118 0.0125
Trichomonas vaginalis set domain proteins, putative 0.1789 1 1
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Brugia malayi histone deacetylase 1 (HD1) 0.0362 0.1887 0.2001
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0118 0.0125
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Trypanosoma cruzi histone deacetylase, putative 0.0103 0.0413 0.0608
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0163 0.0752 0.1532
Onchocerca volvulus Histone deacetylase 10 homolog 0.0103 0.0413 0.0403
Echinococcus granulosus methyltransferase protein 5 0.0032 0.0009 0.001
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0205 0.0988 0.521
Echinococcus multilocularis histone lysine n methyltransferase setb1 0.0038 0.0041 0.0044
Schistosoma mansoni hypothetical protein 0.0132 0.0575 0.0601
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.1887 0.1879
Loa Loa (eye worm) PWWP domain-containing protein 0.0132 0.0575 0.0599
Brugia malayi Carm1-pending protein 0.0163 0.0752 0.0798
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.0052 0.0055
Trypanosoma cruzi spermidine synthase, putative 0.1202 0.6662 1
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0034 0.0021 0.0015
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0205 0.0988 0.5
Echinococcus multilocularis histone h3 methyltransferase 0.1689 0.9429 1
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0617 0.3335 0.9261
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0205 0.0988 0.2727
Schistosoma mansoni microtubule-associated protein tau 0.0778 0.425 0.4502
Trypanosoma cruzi histone-lysine N-methyltransferase, putative 0.0214 0.1045 0.1557
Brugia malayi MTAP 0.1105 0.6106 0.6476
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0118 0.0125
Trypanosoma brucei Histone-lysine N-methyltransferase, H3 lysine-76 specific 0.0214 0.1045 0.1496
Leishmania major arginine N-methyltransferase-like protein 0.0034 0.0021 0.0018
Toxoplasma gondii DNA methyltransferase 2, putative 0.0617 0.3335 0.6854
Echinococcus multilocularis sex peptide receptor 0.0051 0.0118 0.0125
Echinococcus granulosus tyrosine protein kinase Lyn 0.0045 0.0084 0.0089
Trypanosoma brucei spermidine synthase 0.1202 0.6662 1
Trypanosoma brucei Histone methylation protein DOT1, putative 0.0214 0.1045 0.1496
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis bromo adjacent y domain containing 1 0.0047 0.009 0.0095
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0034 0.0021 0.0015
Onchocerca volvulus 0.0403 0.2118 0.2109
Echinococcus granulosus sex peptide receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0118 0.0125
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0041 0.0059 0.0062
Echinococcus multilocularis histone deacetylase 3 0.0362 0.1887 0.2001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0059 0.0062
Toxoplasma gondii adenosylhomocysteinase, putative 0.0664 0.36 0.7401
Leishmania major modification methylase-like protein 0.0617 0.3335 0.4999
Brugia malayi PWWP domain containing protein 0.0132 0.0575 0.061
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0617 0.3335 0.4962
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0118 0.0125
Echinococcus multilocularis uridine phosphorylase 1 0.0205 0.0988 0.1048
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0118 0.0125
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0118 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0118 0.0125
Brugia malayi hypothetical protein 0.0405 0.213 0.2259
Onchocerca volvulus 0.0051 0.0118 0.0106
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0208 0.101 0.1002
Onchocerca volvulus 0.0051 0.0118 0.0106
Onchocerca volvulus 0.0051 0.0118 0.0106
Echinococcus multilocularis histone deacetylase 7 0.0103 0.0413 0.0439
Echinococcus multilocularis purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.1689 0.9429 1
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0132 0.0575 0.0851
Schistosoma mansoni purine nucleoside phosphorylase 0.0205 0.0988 0.104
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0118 0.0115
Onchocerca volvulus 0.0051 0.0118 0.0106
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus multilocularis purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Echinococcus multilocularis geminin 0.019 0.0905 0.096
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0118 0.0125
Leishmania major histone deacetylase, putative 0.0103 0.0413 0.0608
Brugia malayi hypothetical protein 0.0405 0.213 0.2259
Brugia malayi SET domain containing protein 0.0154 0.07 0.0743
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.046 0.2443 0.3656
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0084 0.0089
Echinococcus multilocularis disco interacting protein 2 0.0403 0.2118 0.2246
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0148 0.0665 0.0705
Leishmania major S-adenosylmethionine decarboxylase 0.0945 0.5199 0.78
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Mycobacterium leprae putative S-adenosyl-L-homocysteine hydrolase SahH 0.0664 0.36 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0118 0.0115
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0118 0.0125
Brugia malayi Dopamine receptor protein 1 0.0051 0.0118 0.0125
Loa Loa (eye worm) SET domain-containing protein 0.0154 0.07 0.0732
Plasmodium vivax histone deacetylase 2, putative 0.0103 0.0413 0.0605
Loa Loa (eye worm) Skb1 methyltransferase 0.0064 0.0187 0.0186
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0118 0.0125
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0118 0.0125
Leishmania major histone deacetylase, putative 0.0362 0.1887 0.2822
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Loa Loa (eye worm) histone deacetylase 11 0.0103 0.0413 0.0427
Schistosoma mansoni hypothetical protein 0.0132 0.0575 0.0601
Plasmodium falciparum histone deacetylase 2 0.0103 0.0413 0.0605
Mycobacterium ulcerans S-adenosyl-L-homocysteine hydrolase 0.0664 0.36 0.5103
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0118 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0118 0.0125
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0045 0.0084 0.0089
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0617 0.3335 0.3537
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0242 0.1201 0.1265
Schistosoma mansoni adenosylhomocysteinase 0.0411 0.2161 0.2285
Schistosoma mansoni methylthioadenosine phosphorylase 0.0205 0.0988 0.104
Echinococcus granulosus g protein coupled receptor 0.0051 0.0118 0.0125
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0118 0.0115
Brugia malayi Disco-interacting protein 2 homolog 0.0403 0.2118 0.2246
Schistosoma mansoni protein arginine n-methyltransferase 0.0127 0.0548 0.0572
Schistosoma mansoni neuropeptide receptor 0.0051 0.0118 0.0115
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0205 0.0988 0.1048
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0118 0.0125
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.0084
Toxoplasma gondii hypothetical protein 0.0886 0.4861 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0242 0.1201 0.1274
Leishmania major hypothetical protein, conserved 0.0214 0.1045 0.1557
Leishmania major hypothetical protein, conserved 0.0132 0.0575 0.0851
Schistosoma mansoni phd finger protein 0.0132 0.0575 0.0601
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0118 0.0125
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0118 0.0125
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.163 0.9094 0.9644
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Loa Loa (eye worm) hypothetical protein 0.0405 0.213 0.225
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0118 0.0125
Brugia malayi hypothetical protein 0.0132 0.0575 0.061
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Onchocerca volvulus 0.0051 0.0118 0.0106
Schistosoma mansoni hypothetical protein 0.0058 0.0157 0.0157
Loa Loa (eye worm) spermidine synthase 0.1202 0.6662 0.7062
Echinococcus granulosus disco interacting protein 2 0.0403 0.2118 0.2246
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus neuropeptide s receptor 0.0051 0.0118 0.0125
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0118 0.0125
Trichomonas vaginalis histone deacetylase, putative 0.0362 0.1887 0.1879
Toxoplasma gondii phosphorylase family protein 0.0205 0.0988 0.2018
Brugia malayi Melatonin receptor type 1A 0.0051 0.0118 0.0125
Echinococcus multilocularis histone lysine n methyltransferase suv420h1 0.0154 0.07 0.0743
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0945 0.5199 0.78
Trypanosoma brucei histone deacetylase 1 0.0362 0.1887 0.277
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0205 0.0988 0.2727
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0118 0.0125
Schistosoma mansoni histone deacetylase hda2 0.0103 0.0413 0.0429
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0045 0.0084 0.0089
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.1105 0.6106 0.9164
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0045 0.0084 0.0089
Schistosoma mansoni metastasis-associated protein 1 (mta1) 0.0047 0.009 0.0086
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus neuropeptide receptor A26 0.0051 0.0118 0.0125
Echinococcus granulosus uridine phosphorylase 1 0.0205 0.0988 0.1048
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0118 0.0125
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0617 0.3335 0.4997
Schistosoma mansoni amine GPCR 0.0051 0.0118 0.0115
Echinococcus granulosus g protein coupled receptor 0.0051 0.0118 0.0125
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.046 0.2443 0.3656
Loa Loa (eye worm) histone deacetylase 7A 0.0103 0.0413 0.0427
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0229 0.1128 0.1186
Brugia malayi jmjC domain containing protein 0.0107 0.0434 0.046
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0061 0.0053
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Toxoplasma gondii histone lysine methyltransferase SET1 0.0076 0.026 0.0517
Schistosoma mansoni histone deacetylase 4 5 0.0103 0.0413 0.0429
Mycobacterium tuberculosis Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) 0.0664 0.36 0.6181
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0118 0.0115
Schistosoma mansoni adenosylhomocysteinase 0.0411 0.2161 0.2285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Echinococcus multilocularis serotonin receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) Carm1-pending protein 0.0163 0.0752 0.0787
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0118 0.0115
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Echinococcus granulosus polybromo 1 0.0047 0.009 0.0095
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Trypanosoma cruzi S-adenosylhomocysteine hydrolase, putative 0.0664 0.36 0.5398
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0118 0.0115
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Brugia malayi Histone deacetylase 1 0.0362 0.1887 0.2001
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0011 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0296 0.1508 0.1591
Plasmodium falciparum histone deacetylase, putative 0.0103 0.0413 0.0605
Schistosoma mansoni biogenic amine receptor 0.0051 0.0118 0.0115
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0118 0.0125
Trypanosoma brucei uridine phosphorylase 0.0205 0.0988 0.141
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0205 0.0988 0.098
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0945 0.5199 0.7784
Trypanosoma brucei histone deacetylase 4 0.0103 0.0413 0.054
Schistosoma mansoni jumonji domain containing protein 0.0085 0.0309 0.0318
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0067 0.0205 0.0224
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0118 0.0115
Mycobacterium ulcerans spermidine synthase 0.0948 0.5214 0.8256
Brugia malayi G-protein coupled receptor 0.0051 0.0118 0.0125
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0061 0.0055
Echinococcus granulosus histone deacetylase 1 0.0362 0.1887 0.2001
Schistosoma mansoni histone deacetylase 1 2 3 0.0103 0.0413 0.0429
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Trichomonas vaginalis shk1 kinase-binding protein, putative 0.0041 0.0057 0.0048
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0084 0.0301 0.031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0034 0.0017 0.0009
Echinococcus granulosus histone deacetylase 6 0.0103 0.0413 0.0439
Schistosoma mansoni hypothetical protein 0.0033 0.0011 0.0002
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0118 0.0113
Echinococcus multilocularis metastasis associated protein MTA1 0.0047 0.009 0.0095
Schistosoma mansoni adenosylhomocysteinase 0.0411 0.2161 0.2285
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0159 0.0731 0.0765
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0118 0.0125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0175 0.0821 0.0862
Echinococcus granulosus histone deacetylase 0.0103 0.0413 0.0439
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0084 0.0089
Brugia malayi neuropeptide F receptor 0.0051 0.0118 0.0125
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0067 0.0205 0.0294
Schistosoma mansoni histamine h1 receptor 0.0051 0.0118 0.0115
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0159 0.0731 0.1021
Loa Loa (eye worm) TK protein kinase 0.0041 0.0059 0.0051
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0148 0.0665 0.0705
Brugia malayi ORL1-like opioid receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis protein arginine methyltransferase 0.0034 0.0021 0.0022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Trichomonas vaginalis origin recognition complex subunit, putative 0.0047 0.009 0.0081
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.0321 0.1649 0.1748
Plasmodium falciparum spermidine synthase 0.1202 0.6662 1
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Echinococcus granulosus spermidine synthase 0.1202 0.6662 0.7066
Echinococcus granulosus purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.0095 0.0365 0.0532
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni neuropeptide receptor 0.0051 0.0118 0.0115
Schistosoma mansoni hypothetical protein 0.0047 0.0091 0.0087
Echinococcus granulosus cpg binding protein 0.0385 0.2014 0.2136
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0118 0.0125
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.1128 0.1197
Echinococcus granulosus fmrfamide receptor 0.0051 0.0118 0.0125
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0163 0.0752 0.0798
Trypanosoma brucei S-adenosylhomocysteine hydrolase, putative 0.0664 0.36 0.5364
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0118 0.0115
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0118 0.0125
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.0945 0.5199 0.5514
Onchocerca volvulus 0.0047 0.0091 0.008
Brugia malayi Spermidine synthase 0.1202 0.6662 0.7066
Brugia malayi Pre-SET motif family protein 0.0213 0.1037 0.11
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0034 0.0021 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Leishmania major spermidine synthase 0.1202 0.6662 1
Brugia malayi sulfakinin receptor protein 0.0051 0.0118 0.0125
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0118 0.0125
Brugia malayi Adenosylhomocysteinase 0.0664 0.36 0.3818
Entamoeba histolytica Skb1 methyltransferase, putative 0.0064 0.0187 0.0494
Onchocerca volvulus 0.0051 0.0118 0.0106
Echinococcus multilocularis arginine glutamic acid dipeptide (RE) repeats 0.0047 0.009 0.0095
Loa Loa (eye worm) hypothetical protein 0.0038 0.0041 0.0032
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0118 0.0125
Schistosoma mansoni hepatoma derived growth factor 0.0132 0.0575 0.0601
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0034 0.0021 0.0013
Loa Loa (eye worm) hypothetical protein 0.0132 0.0575 0.0599
Treponema pallidum pfs protein (pfs) 0.0205 0.0988 0.5
Brugia malayi ELM2 domain containing protein 0.0047 0.009 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0205 0.0988 0.098
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni histone deacetylase 0.0362 0.1887 0.1993
Brugia malayi protein-tyrosine kinase 0.0041 0.0059 0.0062
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0118 0.0113
Loa Loa (eye worm) SRC-1 0.0045 0.0084 0.0077
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0132 0.0575 0.0851
Schistosoma mansoni adenosylhomocysteinase 0.0411 0.2161 0.2285
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0034 0.0021 0.0012
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0362 0.1887 0.1879
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0118 0.0125
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0205 0.0988 0.2727
Brugia malayi Serotonin receptor 0.0051 0.0118 0.0125
Schistosoma mansoni cpg binding protein 0.0385 0.2014 0.2128
Brugia malayi AKH receptor 0.0051 0.0118 0.0125
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0205 0.0988 0.1469
Echinococcus granulosus bromo adjacent y domain containing 1 0.0047 0.009 0.0095
Echinococcus multilocularis microtubule associated protein 2 0.0778 0.425 0.4507
Echinococcus multilocularis purine nucleoside phosphorylase 0.0205 0.0988 0.1048
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0118 0.0115
Leishmania major histone deacetylase, putative 0.0362 0.1887 0.2822
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0617 0.3335 0.6854
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0118 0.0115
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0132 0.0575 0.0851
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.1689 0.9429 1
Loa Loa (eye worm) hypothetical protein 0.0405 0.213 0.225
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0205 0.0988 0.521
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis protein arginine N methyltransferase 5 0.0064 0.0187 0.0198
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Schistosoma mansoni hypothetical protein 0.0051 0.0118 0.0115
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0118 0.0115
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0118 0.0125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0118 0.0113
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0028 0.003
Plasmodium falciparum protein arginine N-methyltransferase 5, putative 0.0064 0.0187 0.0264
Trypanosoma cruzi spermidine synthase, putative 0.1202 0.6662 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.0084
Echinococcus multilocularis SET and MYND domain containing protein 3 0.0079 0.0276 0.0292
Echinococcus granulosus DNA methyltransferase 2, putative 0.0617 0.3335 0.3537
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0945 0.5199 0.78
Echinococcus multilocularis somatostatin receptor 0.0051 0.0118 0.0125
Trichomonas vaginalis adenosylhomocysteinase, putative 0.0664 0.36 0.3594
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0118 0.0115
Schistosoma mansoni survival motor neuron protein 0.0047 0.0091 0.0087
Onchocerca volvulus 0.0051 0.0118 0.0106
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0205 0.0988 0.0978
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0118 0.0115
Echinococcus multilocularis tyrosine protein kinase Srms 0.0041 0.0059 0.0062
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0084 0.0089
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0118 0.0125
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0118 0.0113
Trypanosoma brucei histone deacetylase 2 0.0103 0.0413 0.054
Brugia malayi hypothetical protein 0.0051 0.0118 0.0125
Loa Loa (eye worm) TK protein kinase 0.0036 0.0033 0.0023
Echinococcus granulosus SET and MYND domain containing protein 3 0.0079 0.0276 0.0292
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0118 0.0113
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0011 0.0004
Brugia malayi larval opioid receptor 0.0051 0.0118 0.0125
Schistosoma mansoni adenoreceptor 0.0051 0.0118 0.0115
Schistosoma mansoni adenosylhomocysteinase 0.0664 0.36 0.3812
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0107 0.0434 0.046
Echinococcus multilocularis neuropeptide s receptor 0.0051 0.0118 0.0125
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.1105 0.6106 1
Brugia malayi SRC-1 0.0045 0.0084 0.0089
Echinococcus granulosus tyrosine protein kinase Src42A 0.0045 0.0084 0.0089
Toxoplasma gondii histone deacetylase HDAC3 0.0362 0.1887 0.387
Schistosoma mansoni amine GPCR 0.0051 0.0118 0.0115
Schistosoma mansoni uridine phosphorylase 0.0205 0.0988 0.104

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2300 nM Binding affinity towards p60 Src tyrosine kinase using scintillation proximity assay ChEMBL. 11965373
IC50 (binding) = 2300 nM Binding affinity towards p60 Src tyrosine kinase using scintillation proximity assay ChEMBL. 11965373

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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