Detailed information for compound 306322

Basic information

Technical information
  • TDR Targets ID: 306322
  • Name: N-(3-bromophenyl)-3-(2-dimethylaminoethyl)imi dazo[4,5-g]quinazolin-8-amine
  • MW: 411.298 | Formula: C19H19BrN6
  • H donors: 1 H acceptors: 3 LogP: 3.6 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCn1cnc2c1cc1ncnc(c1c2)Nc1cccc(c1)Br)C
  • InChi: 1S/C19H19BrN6/c1-25(2)6-7-26-12-23-17-9-15-16(10-18(17)26)21-11-22-19(15)24-14-5-3-4-13(20)8-14/h3-5,8-12H,6-7H2,1-2H3,(H,21,22,24)
  • InChiKey: CAHQBZBYEQNNHC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-bromophenyl)-3-(2-dimethylaminoethyl)-8-imidazo[4,5-g]quinazolinamine
  • 2-[8-(3-bromoanilino)imidazo[4,5-g]quinazolin-3-yl]ethyl-dimethyl-amine
  • 2-[8-[(3-bromophenyl)amino]imidazo[4,5-g]quinazolin-3-yl]ethyl-dimethyl-amine
  • Imidazoquinazoline deriv. 13

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens epidermal growth factor receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Receptor tyrosine-protein kinase erbB-2 precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum IPR006212,Furin-like repeat;IPR009030,Growth factor, receptor,domain-containing Get druggable targets OG5_128597 All targets in OG5_128597
Brugia malayi Furin-like cysteine rich region family protein Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Tyrosine-protein kinase transforming protein erbB, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum ko:K05085 receptor tyrosine-protein kinase erbB-4, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Loa Loa (eye worm) TK/EGFR protein kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum IPR000494,EGF receptor, L domain,domain-containing Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus multilocularis epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus granulosus melanoma receptor tyrosine protein kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Receptor tyrosine-protein kinase erbB-4 precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus multilocularis epidermal growth factor receptor Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum expressed protein Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Echinococcus multilocularis Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma japonicum Epidermal growth factor receptor precursor, putative Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
Schistosoma mansoni tyrosine kinase Get druggable targets OG5_128597 All targets in OG5_128597
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0102
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0063 0.0033 0.0033
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0086 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Plasmodium falciparum bromodomain protein 1 0.0015 0.0000000024747 0.0000000024747
Schistosoma mansoni ferritin 0.0035 0.0014 0.0014
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0124 0.0076 0.1941
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.003
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0003 0.0003
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0297 0.0197 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0042 0.0019 0.0026
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0002 0.0002
Echinococcus granulosus inositol monophosphatase 1 0.0117 0.0071 0.0071
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.057 0.0388 1
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Echinococcus granulosus peregrin 0.0043 0.002 0.002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Brugia malayi Death domain containing protein 0.0016 0.0001 0.0001
Echinococcus granulosus sex peptide receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Trichomonas vaginalis guanylate cyclase, putative 0.0085 0.0049 0.1202
Echinococcus multilocularis lamin 0.0056 0.0029 0.0029
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0016 0.0016
Brugia malayi PXA domain containing protein 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0384 0.0258 0.0258
Plasmodium falciparum glutathione reductase 0.0047 0.0022 0.0022
Brugia malayi Thioredoxin reductase 0.0135 0.0084 0.0084
Echinococcus multilocularis apoptotic protease activating factor 1 0.0085 0.0049 0.0049
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0004 0.009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0049 0.0024 0.0024
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor E75 0.0077 0.0043 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.0122 0.3109
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0361 0.0242 0.4825
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0003 0.0004
Loa Loa (eye worm) RNA binding protein 0.0067 0.0037 0.0037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0024 0.0024
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0292 0.0194 0.4958
Brugia malayi hypothetical protein 0.0384 0.0258 0.0258
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0217 0.0141 0.0141
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0004 0.0004
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0047 0.0022 0.003
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0031 0.0031
Mycobacterium leprae Possible regulatory protein 0.0085 0.0049 0.1198
Brugia malayi hypothetical protein 0.0086 0.005 0.005
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 1.0655 0.7431 1
Brugia malayi neuropeptide F receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0004 0.0004
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0003 0.0031
Schistosoma mansoni biogenic amine receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.002 0.0004 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0193 0.0125 0.3063
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0004 0.0004
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0002 0.0002
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0194 0.0125 0.0125
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.002 0.0004 0.0073
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0004 0.0004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.0024 0.0032
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.019 0.0122 0.3131
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0005 0.0005
Mycobacterium ulcerans DNA polymerase IV 0.01 0.006 0.1485
Onchocerca volvulus 0.002 0.0004 0.0073
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0064
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0022 0.0022
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0005 0.0005
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0004 0.0058
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0019 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0037 0.0037
Mycobacterium ulcerans putative regulatory protein 0.0219 0.0143 0.3643
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0733 0.0502 1
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0002 0.0003
Schistosoma mansoni caspase-7 (C14 family) 0.024 0.0157 0.0157
Schistosoma mansoni lamin 0.0056 0.0029 0.0029
Onchocerca volvulus 0.0077 0.0043 0.0866
Mycobacterium tuberculosis Probable dehydrogenase 0.0308 0.0205 0.5264
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0017 0.0017
Brugia malayi Furin-like cysteine rich region family protein 0.018 0.0115 0.0115
Brugia malayi intermediate filament protein 0.0056 0.0029 0.0029
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0004
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0071 0.0096
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Leishmania major GTP-binding protein, putative 0.0022 0.0005 0.0007
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0028
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.005
Loa Loa (eye worm) cysteine protease 0.0018 0.0002 0.0002
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0003 0.0036
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi Pax transcription factor protein 2 0.0733 0.0502 0.0502
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0016 0.0021
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0161 0.0102 0.0102
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0047
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.005
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0005 0.0005
Brugia malayi Serotonin receptor 0.0018 0.0002 0.0002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0016 0.0021
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0017 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0023 0.0558
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0163 0.0104 0.0104
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0059
Brugia malayi Pre-SET motif family protein 0.0064 0.0035 0.0035
Schistosoma mansoni aldehyde dehydrogenase 0.019 0.0122 0.0122
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.005 0.0067
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0022 0.0022
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0001 0.0001
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0101 0.0101
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Trichomonas vaginalis glutathione reductase, putative 0.0047 0.0022 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0017 0.041
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0301 0.02 0.4919
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0004 0.0005
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0096 0.0057 0.0077
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0003 0.0003
Brugia malayi ATPase, AAA family protein 0.0015 0.000000080466 0.000000080466
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0045 0.0021 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0077 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.008 0.0045 0.114
Echinococcus multilocularis insulin receptor 0.0058 0.003 0.003
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0163 0.0104 0.0104
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.009
Schistosoma mansoni Smad4 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0007
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0077 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.061 0.0416 0.0416
Trypanosoma brucei ATP-binding cassette protein, putative 0.002 0.0004 0.0005
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0008 0.0188
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0163 0.0104 0.0104
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0004 0.0005
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0002 0.0002
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0096 0.0057 0.0057
Trypanosoma cruzi DNA topoisomerase III, putative 0.0266 0.0176 0.0237
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Entamoeba histolytica DNA topoisomerase III, putative 0.0135 0.0084 0.2063
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0042 0.0019 0.0026
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0004 0.0005
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0004 0.009
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0002 0.0002
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0009 0.0012
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0073 0.0041 0.0041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Echinococcus multilocularis expressed protein 0.0404 0.0272 0.0272
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0017 0.0017
Echinococcus multilocularis thyroid hormone receptor alpha 0.0163 0.0104 0.0104
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0004 0.0005
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus orexin receptor type 2 0.0018 0.0002 0.0002
Brugia malayi Glycosyl hydrolases family 31 protein 0.0018 0.0002 0.0002
Trypanosoma cruzi ABC transporter, putative 0.002 0.0004 0.0005
Echinococcus granulosus importin subunit beta 1 0.003 0.0011 0.0011
Plasmodium falciparum JmjC domain-containing protein, putative 0.0042 0.0019 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0024 0.0586
Loa Loa (eye worm) globin family protein 0.0027 0.0008 0.0008
Entamoeba histolytica DNA topoisomerase III, putative 0.0259 0.0171 0.4193
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0163 0.0104 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Brugia malayi ecdysteroid receptor 0.0163 0.0104 0.0104
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Echinococcus multilocularis tumor protein p63 0.0366 0.0245 0.0245
Treponema pallidum bacterioferrin (TpF1) 0.0035 0.0014 0.0285
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0189 0.0122 0.0122
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0059 0.0031 0.0031
Brugia malayi hypothetical protein 0.0077 0.0043 0.0043
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0004 0.0004
Echinococcus multilocularis importin subunit beta 1 0.003 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0012 0.0288
Brugia malayi MH1 domain containing protein 0.0042 0.0019 0.0019
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0163 0.0104 0.0104
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0003 0.0064
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0004 0.0058
Schistosoma mansoni nuclear receptor 0.0077 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi G protein-coupled receptor 0.0018 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0053 0.0053
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0004 0.0004
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0185 0.0119 0.0119
Leishmania major hypothetical protein, conserved 0.0069 0.0038 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0212 0.0138 0.0138
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0017 0.0017
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0047 0.0022 0.0022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0009 0.0009
Echinococcus granulosus kelch ECH associated protein 1 like 0.0095 0.0056 0.0056
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Onchocerca volvulus 0.002 0.0004 0.0073
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0001 0.0001
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0037 0.0037
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.024 0.0157 0.0157
Echinococcus granulosus zinc finger protein 0.0018 0.0002 0.0002
Echinococcus multilocularis 0.0416 0.028 0.028
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0029 0.0029
Schistosoma mansoni tsg101-related 0.0058 0.003 0.003
Schistosoma mansoni DNA topoisomerase type I 1.0655 0.7431 0.7431
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0058 0.0058
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0047 0.0022 0.0022
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.002 0.0004 0.0005
Loa Loa (eye worm) isocitrate dehydrogenase 0.0096 0.0057 0.0057
Brugia malayi Pre-SET motif family protein 0.0441 0.0298 0.0298
Brugia malayi Protein kinase domain containing protein 0.0058 0.003 0.003
Trichomonas vaginalis ran, putative 0.0022 0.0005 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0037 0.0037
Leishmania major DNA topoisomerase type IB small subunit 0.5172 0.3602 0.4847
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.0125 0.0125
Echinococcus multilocularis somatostatin receptor 0.0018 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni prokaryotic DNA topoisomerase 0.031 0.0206 0.0206
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis caspase 0.024 0.0157 0.0157
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0004 0.0004
Echinococcus granulosus FTZ F1 alpha 0.0163 0.0104 0.0104
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0007 0.0168
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0301 0.02 0.02
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0303 0.0201 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0027 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0101 0.0101
Echinococcus multilocularis protein dispatched 1 0.0047 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0024 0.0581
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0001 0.0001
Brugia malayi DNA topoisomerase III 0.0266 0.0176 0.0176
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0037 0.005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0163 0.0104 0.0104
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0037 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1 0.0018 0.0002 0.0002
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0002 0.0002
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0177 0.0114 0.0114
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0002 0.0002
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0086 0.005 0.005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0096 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0016 0.0381
Echinococcus multilocularis JmjC domain containing protein 4 0.0042 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0002 0.0047
Brugia malayi G-protein coupled receptor 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0833 0.0571 0.0571
Trichomonas vaginalis DNA polymerase eta, putative 0.01 0.006 0.1469
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0042 0.0019 0.0019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0502 0.034 0.678
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0002 0.0002
Brugia malayi MH1 domain containing protein 0.0023 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.1219 0.0841 0.0841
Trypanosoma brucei metacaspase 5, putative 0.0091 0.0053 0.0071
Leishmania major hypothetical protein, conserved 0.013 0.0081 0.0109
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.0122 0.3109
Loa Loa (eye worm) hypothetical protein 0.017 0.0109 0.0109
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0002 0.0002
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0076 0.0043 0.1054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0049 0.0024 0.0024
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Echinococcus multilocularis conserved hypothetical protein 0.0747 0.0511 0.0511
Leishmania major DNA polymerase eta, putative 0.0074 0.0042 0.0056
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0163 0.0104 0.0104
Entamoeba histolytica Ran family GTPase 0.0022 0.0005 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0003 0.0036
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0002 0.0043
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0017 0.0017
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0002 0.0002
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0002 0.0047
Schistosoma mansoni retinal dehydrogenase 0.002 0.0004 0.0004
Onchocerca volvulus 0.002 0.0004 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0003 0.0004
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0006 0.0007
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0012 0.0306
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0034 0.0045
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0019 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Echinococcus multilocularis 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0163 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0002 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0002 0.0002
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0085 0.0049 0.0049
Onchocerca volvulus 0.0135 0.0084 0.1674
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0004 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.008 0.0045 0.0061
Trypanosoma brucei DNA topoisomerase III, putative 0.0135 0.0084 0.0113
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus granulosus caspase 2 0.0175 0.0112 0.0112
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Giardia lamblia GTOR 0.0049 0.0024 0.0581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0003 0.0036
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0004 0.0004
Schistosoma mansoni dishevelled 0.0018 0.0002 0.0002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0598 0.0407 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0029 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0017 0.0017
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0308 0.0205 0.5264
Schistosoma mansoni phd/f-box containing protein 0.0042 0.0019 0.0019
Brugia malayi DIX domain containing protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0047 0.0022 0.0513
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0077 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0059 0.0031 0.0031
Schistosoma mansoni opsin-like receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Giardia lamblia DNA topoisomerase III 0.0259 0.0171 0.4193
Onchocerca volvulus Protein ultraspiracle homolog 0.0163 0.0104 0.2066
Plasmodium falciparum DNA topoisomerase 3, putative 0.0259 0.0171 0.0171
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0004 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0004 0.0005
Plasmodium vivax importin-beta 2, putative 0.003 0.0011 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0024 0.0586
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0001 0.0001
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.028 0.0185 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Toxoplasma gondii SWI2/SNF2-containing protein 0.0044 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.001 0.024
Trichomonas vaginalis guanylate cyclase, putative 0.0085 0.0049 0.1202
Schistosoma mansoni steroid hormone receptor ad4bp 0.0163 0.0104 0.0104
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0086 0.005 0.005
Onchocerca volvulus 0.0027 0.0008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus ecdysone induced protein 78C 0.0163 0.0104 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0005 0.0005
Plasmodium vivax SET domain protein, putative 0.0064 0.0035 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0038 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0037 0.0037
Onchocerca volvulus 0.0018 0.0002 0.0043
Brugia malayi PAS domain containing protein 0.0304 0.0202 0.0202
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.005
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0604 0.0411 0.0411
Schistosoma mansoni ferritin 0.0035 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0096 0.0057 0.0077
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0055 0.0028 0.0028
Brugia malayi hypoxia-induced factor 1 0.0918 0.0631 0.0631
Schistosoma mansoni ferritin 0.0035 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0018 0.0002 0.0002
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0004
Giardia lamblia Kinase, PLK 0.0194 0.0125 0.308
Echinococcus granulosus thyroid hormone receptor alpha 0.0077 0.0043 0.0043
Entamoeba histolytica serine/threonine protein kinase, putative 0.0194 0.0125 0.308
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0085 0.0049 0.0049
Brugia malayi Nuclear hormone receptor E75 0.0077 0.0043 0.0043
Echinococcus multilocularis smad 0.0042 0.0019 0.0019
Schistosoma mansoni caspase-3 (C14 family) 0.024 0.0157 0.0157
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0069 0.0038 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0038 0.0051
Brugia malayi Bromodomain containing protein 0.0018 0.0002 0.0002
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0086 0.005 0.0067
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0028 0.0037
Schistosoma mansoni transcription factor LCR-F1 0.0301 0.02 0.02
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0047 0.0022 0.003
Brugia malayi MH2 domain containing protein 0.061 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0054 0.0027 0.0027
Echinococcus granulosus neuropeptide receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0002 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0042 0.0019 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0077 0.0043 0.0043
Leishmania major hypothetical protein, conserved 0.002 0.0004 0.0005
Trypanosoma brucei DNA topoisomerase III, putative 0.0266 0.0176 0.0237
Mycobacterium tuberculosis Probable monooxygenase 0.0027 0.0008 0.0177
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0002 0.0002
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0077 0.0043 0.0043
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0086 0.0086
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0003 0.0004
Schistosoma mansoni alpha glucosidase 0.0049 0.0024 0.0024
Trichomonas vaginalis maltase-glucoamylase, putative 0.0049 0.0024 0.0586
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0038 0.0051
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0604 0.0411 0.0411
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0003 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0037 0.0037
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0177 0.0114 0.2791
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0002 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Leishmania major DNA topoisomerase IB, large subunit 1.0655 0.7431 1
Loa Loa (eye worm) inositol-1 0.0117 0.0071 0.0071
Schistosoma mansoni microtubule-associated protein tau 0.1411 0.0975 0.0975
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Plasmodium falciparum ataxin-2 like protein, putative 0.013 0.0081 0.0081
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0095 0.0056 0.0056
Echinococcus granulosus JmjC domain containing protein 4 0.0042 0.0019 0.0019
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0018 0.0002 0.0002
Leishmania major pteridine reductase 1 0.002 0.0004 0.0005
Schistosoma mansoni cpg binding protein 0.0058 0.0031 0.0031
Brugia malayi orphan nuclear receptor NR2E1 0.0077 0.0043 0.0043
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0259 0.0171 0.023
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0004 0.0004
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0004 0.009
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0003 0.0036
Brugia malayi putative neuropeptide receptor 0.0018 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0004 0.0004
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0008 0.0131
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0037 0.0037
Brugia malayi jmjC domain containing protein 0.0217 0.0141 0.0141
Echinococcus multilocularis musashi 0.0056 0.0029 0.0029
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0002 0.0059
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0003 0.0004
Echinococcus granulosus dnaJ subfamily B 0.0833 0.0571 0.0571
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0135 0.0084 0.0084
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0062 0.0033 0.0033
Echinococcus multilocularis caspase 2 0.0175 0.0112 0.0112
Schistosoma mansoni amine GPCR 0.0018 0.0002 0.0002
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0096 0.0057 0.0057
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0003 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.008 0.0045 0.0061
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis zinc finger protein 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0077 0.0043 0.0043
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0163 0.0104 0.0104
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0037 0.005
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0096 0.0057 0.1437
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0002 0.0002
Schistosoma mansoni alpha-glucosidase 0.0129 0.008 0.008
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0042 0.0019 0.0019
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Echinococcus granulosus nuclear receptor nhr 48 0.0077 0.0043 0.0043
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0163 0.0104 0.0104
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.002 0.0004 0.0004
Loa Loa (eye worm) hypoxia-induced factor 1 0.0918 0.0631 0.0631
Treponema pallidum DNA topoisomerase I (topA) 0.0303 0.0201 0.4914
Schistosoma mansoni tyrosine kinase 0.018 0.0115 0.0115
Schistosoma mansoni phosphatidylserine receptor 0.0042 0.0019 0.0019
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.0022 0.0993
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.1133 0.0781 0.0781
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0185 0.4543
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0077 0.0043 0.0866
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0163 0.0104 0.0104
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0008 0.0008
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0002 0.0002
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0004 0.009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0006 0.0006
Plasmodium vivax glutathione reductase, putative 0.0135 0.0084 0.0084
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.0017 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Loa Loa (eye worm) hypothetical protein 0.0082 0.0047 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Brugia malayi ImpB/MucB/SamB family protein 0.0125 0.0077 0.0077
Mycobacterium ulcerans bacterioferritin BfrB 0.0035 0.0014 0.0299
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0185 0.0119 0.0119
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0022 0.003
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0016 0.0016
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0003
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0042 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0004 0.0027
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Echinococcus multilocularis phd:f box containing protein 0.0042 0.0019 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.0078 0.0078
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0073 0.0041 0.0041
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0077 0.0043 0.0043
Schistosoma mansoni smad 0.0019 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0086 0.005 0.005
Loa Loa (eye worm) TOPoisomerase family member 0.0059 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0005 0.0005
Echinococcus granulosus kelch ECH associated protein 1 0.0095 0.0056 0.0056
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0027 0.0027
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0097 0.0057 0.0057
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0002 0.0002
Onchocerca volvulus 0.002 0.0004 0.0073
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0004 0.009
Loa Loa (eye worm) hypothetical protein 0.1458 0.1008 0.1008
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0004 0.0004
Onchocerca volvulus 0.0018 0.0002 0.0043
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0037
Plasmodium vivax hypothetical protein, conserved 0.0029 0.001 0.001
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0023
Brugia malayi ORL1-like opioid receptor 0.0018 0.0002 0.0002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0002 0.0002
Giardia lamblia Histone acetyltransferase GCN5 0.0163 0.0103 0.2538
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0026
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0056 0.0029 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.0024 0.0032
Brugia malayi polk-prov protein 0.005 0.0025 0.0025
Leishmania major DNA polymerase eta, putative 0.0125 0.0077 0.0103
Brugia malayi Glycosyl hydrolases family 31 protein 0.0049 0.0024 0.0024
Brugia malayi GRF zinc finger family protein 0.0066 0.0036 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0002 0.0002
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Echinococcus multilocularis jun protein 0.0084 0.0048 0.0048
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0009 0.022
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.003 0.004
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0073 0.0041 0.0041
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0008 0.001
Echinococcus granulosus microtubule associated protein 2 0.1411 0.0975 0.0975
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Echinococcus granulosus cathepsin l1 0.0018 0.0002 0.0002
Mycobacterium ulcerans bacterioferritin BfrA 0.0035 0.0014 0.0299
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0017 0.0017
Schistosoma mansoni neuropeptide receptor 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Schistosoma mansoni DNA polymerase eta 0.0125 0.0077 0.0077
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.019 0.0122 0.0165
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0342 0.0229 0.5885
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0003 0.0003
Brugia malayi Melatonin receptor type 1A 0.0018 0.0002 0.0002
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0017 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Echinococcus multilocularis muscleblind protein 1 0.0619 0.0422 0.0422
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0004 0.0058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Echinococcus granulosus intermediate filament protein 0.0056 0.0029 0.0029
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.001 0.001
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0018 0.0002 0.0047
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0007
Onchocerca volvulus 0.0056 0.0029 0.0576
Brugia malayi hypothetical protein 0.1458 0.1008 0.1008
Mycobacterium ulcerans monooxygenase 0.0027 0.0008 0.0146
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0018 0.0002 0.0048
Echinococcus granulosus tumor susceptibility gene 101 protein 0.007 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0301 0.02 0.02
Giardia lamblia DNA topoisomerase II 0.0059 0.0031 0.0755
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0005 0.0007
Echinococcus granulosus caspase 8 0.0091 0.0053 0.0053
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Brugia malayi GnHR receptor homolog 0.0018 0.0002 0.0002
Brugia malayi MH2 domain containing protein 0.0042 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0017 0.0017
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.001 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.013 0.0081 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.001 0.0245
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0002 0.0002
Echinococcus granulosus histone acetyltransferase KAT2B 0.0587 0.0399 0.0399
Brugia malayi DNA topoisomerase III beta-1 0.0135 0.0084 0.0084
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0004 0.0004
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0004 0.0027
Brugia malayi jmjC domain containing protein 0.0042 0.0019 0.0019
Brugia malayi PHD-finger family protein 0.0018 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0025 0.0007 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Loa Loa (eye worm) nuclear factor I 0.0023 0.0006 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0037 0.0037
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0011 0.0011
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0037 0.005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0003 0.0036
Schistosoma mansoni protein phosphatase 2C 0.0042 0.0019 0.0019
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0086 0.005 0.0067
Schistosoma mansoni DNA topoisomerase type I 1.0655 0.7431 0.7431
Giardia lamblia NADH oxidase lateral transfer candidate 0.0047 0.0022 0.0549
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0003
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0002 0.0002
Brugia malayi mbt repeat family protein 0.0047 0.0022 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.057 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Giardia lamblia DINP protein human, muc B family 0.008 0.0045 0.1116
Echinococcus multilocularis FTZ F1 alpha 0.0163 0.0104 0.0104
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0037 0.0037
Trypanosoma brucei glycosyl hydrolase-like protein 0.0018 0.0002 0.0003
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0004 0.0027
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0085 0.0049 0.0049
Plasmodium falciparum thioredoxin reductase 0.0135 0.0084 0.0084
Echinococcus granulosus Ankyrin 0.0016 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0018 0.0002 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0024 0.0024
Onchocerca volvulus 0.0085 0.0049 0.0971
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0049 0.0024 0.0586
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0212 0.0138 0.0138
Echinococcus granulosus g protein coupled receptor 0.0018 0.0002 0.0002
Brugia malayi nuclear hormone receptor 0.0077 0.0043 0.0043
Schistosoma mansoni apoferritin-2 0.0035 0.0014 0.0014
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0038 0.0051
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0004 0.0004
Mycobacterium ulcerans dehydrogenase 0.002 0.0004 0.0027
Leishmania major DNA topoisomerase III, putative 0.0135 0.0084 0.0113
Echinococcus granulosus hypothetical protein 0.0765 0.0524 0.0524
Leishmania major importin beta-1 subunit, putative 0.0025 0.0007 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0002 0.0003
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0042 0.0019 0.0019
Toxoplasma gondii oxidoreductase, putative 0.002 0.0004 0.0004
Brugia malayi jmjC domain containing protein 0.0042 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.0069 0.0038 0.0051
Entamoeba histolytica hypothetical protein 0.0301 0.02 0.4919
Plasmodium falciparum importin beta, putative 0.003 0.0011 0.0011
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0002 0.0002
Plasmodium vivax metacaspase 1, putative 0.0091 0.0053 0.0053
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0129
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.0022 0.003
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0003 0.0036
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0002 0.0002
Leishmania major oxidoreductase-like protein 0.002 0.0004 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Leishmania major adenylate cyclase-like protein 0.0027 0.0008 0.0011
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0135 0.0084 0.0084
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0059 0.0031 0.0041
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0057 0.0057
Echinococcus granulosus geminin 0.1219 0.0841 0.0841
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0016 0.0021
Loa Loa (eye worm) ABC transporter 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0077 0.0043 0.0866
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0004 0.0027
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0047 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Echinococcus multilocularis muscleblind protein 0.0619 0.0422 0.0422
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0002 0.0002
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0004 0.0027
Mycobacterium ulcerans DNA topoisomerase I 0.0259 0.0171 0.4364
Onchocerca volvulus 0.0018 0.0002 0.0043
Plasmodium falciparum flap endonuclease 1 0.0028 0.0009 0.0009
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0004 0.009
Entamoeba histolytica cysteine protease, putative 0.0018 0.0002 0.0057
Echinococcus granulosus lysine specific demethylase 5A 0.0161 0.0102 0.0102
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0003 0.0053
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.0298 0.0298
Leishmania major short chain dehydrogenase, putative 0.002 0.0004 0.0005
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0004 0.0005
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0004 0.0004
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Echinococcus granulosus hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0009 0.022
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0004 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0096 0.0057 0.0057
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0004 0.0005
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0004 0.0058
Echinococcus granulosus neuropeptide receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.002 0.0004 0.0023
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0054 0.0027 0.054
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0045 0.0021 0.0021
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.019 0.0122 0.0122
Echinococcus multilocularis neutral alpha glucosidase AB 0.0049 0.0024 0.0024
Toxoplasma gondii exonuclease III APE 0.0019 0.0003 0.0003
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0024 0.0586
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0163 0.0104 0.0104
Trypanosoma cruzi metacaspase, putative 0.0091 0.0053 0.0071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0185 0.0119 0.302
Schistosoma mansoni inositol monophosphatase 0.0117 0.0071 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0035 0.0035
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Leishmania major DNA topoisomerase III, putative 0.031 0.0206 0.0278
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0004 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Trypanosoma brucei membrane transporter protein, putative 0.0069 0.0038 0.0051
Schistosoma mansoni tsg101-related 0.0047 0.0023 0.0023
Onchocerca volvulus 0.002 0.0004 0.0073
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0003 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0071 0.0096
Onchocerca volvulus 0.0018 0.0002 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Brugia malayi conserved hypotetical protein 0.0077 0.0043 0.0043
Schistosoma mansoni tyrosine kinase 0.0058 0.003 0.003
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0004 0.009
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0056 0.0029 0.0029
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0022 0.0022
Onchocerca volvulus Huntingtin homolog 0.0384 0.0258 0.5134
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Brugia malayi jmjC domain containing protein 0.0042 0.0019 0.0019
Trypanosoma cruzi DNA polymerase eta, putative 0.0125 0.0077 0.0103
Plasmodium vivax DNA topoisomerase II, putative 0.0059 0.0031 0.0031
Echinococcus multilocularis isocitrate dehydrogenase 0.0096 0.0057 0.0057
Toxoplasma gondii cathepsin CPL 0.0018 0.0002 0.0002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0163 0.0104 0.2066
Brugia malayi nuclear hormone receptor family member nhr-6 0.0077 0.0043 0.0043
Echinococcus granulosus dna polymerase eta 0.0125 0.0077 0.0077
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.0216 0.0216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.0094 0.0055 0.0074
Echinococcus multilocularis microtubule associated protein 2 0.1411 0.0975 0.0975
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0017 0.0001 0.0037
Schistosoma mansoni flap endonuclease-1 0.0025 0.0007 0.0007
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0009 0.0012
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0059 0.0031 0.0759
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0002 0.0002
Trypanosoma cruzi membrane transporter protein, putative 0.0069 0.0038 0.0051
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0059 0.0031 0.0031
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0003
Echinococcus granulosus tar DNA binding protein 0.0067 0.0037 0.0037
Echinococcus multilocularis dna polymerase kappa 0.01 0.006 0.006
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0008 0.0131
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0096 0.0057 0.0057
Schistosoma mansoni neuropeptide receptor 0.0018 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0031 0.0031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0077 0.0043 0.0043
Schistosoma mansoni carbonyl reductase 0.002 0.0004 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0197
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0163 0.0104 0.2066
Entamoeba histolytica hypothetical protein 0.0301 0.02 0.4919
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0165 0.0105 0.0105
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0047 0.0022 0.0022
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0006 0.0007
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0002 0.0002
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.001 0.001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0002 0.0002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0301 0.02 0.02
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0035 0.0035
Echinococcus granulosus hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0002 0.0002
Leishmania major short chain dehydrogenase, putative 0.002 0.0004 0.0005
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.001 0.024
Onchocerca volvulus Glucosylceramidase homolog 0.0183 0.0118 0.2348
Echinococcus granulosus carbonyl reductase 1 0.002 0.0004 0.0004
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0004 0.0004
Echinococcus granulosus g protein coupled receptor 0.0018 0.0002 0.0002
Echinococcus granulosus TGF beta signal transducer SmadC 0.0042 0.0019 0.0019
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0017 0.0023
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0117 0.0071 0.1782
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0016 0.0016
Brugia malayi nuclear receptor NHR-67 0.0077 0.0043 0.0043
Echinococcus granulosus apoptotic protease activating factor 1 0.0085 0.0049 0.0049
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0004 0.0058
Schistosoma mansoni single-minded 0.0304 0.0202 0.0202
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0003 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) hypothetical protein 0.0064 0.0035 0.0035
Brugia malayi hypothetical protein 0.0084 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0196
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0096 0.0057 0.0077
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0004 0.0004
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0004 0.009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0047 0.0022 0.0513
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0004
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0005 0.0005
Schistosoma mansoni ferritin light chain 0.0035 0.0014 0.0014
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0096 0.0057 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.003 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0049 0.1202
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0003 0.0004
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0004 0.0004
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0185 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0027 0.0027
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0002 0.0002
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0035 0.0014 0.0295
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0042 0.0019 0.0019
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0117 0.0071 0.3454
Trichomonas vaginalis mercuric reductase, putative 0.0047 0.0022 0.0549
Trypanosoma cruzi polo-like protein kinase, putative 0.0194 0.0125 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0193 0.0125 0.3063
Echinococcus granulosus kelch ECH associated protein 1 like 0.0095 0.0056 0.0056
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.0024 0.0032
Onchocerca volvulus 0.0064 0.0035 0.069
Trypanosoma cruzi DNA topoisomerase III, putative 0.0266 0.0176 0.0237
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0058
Schistosoma mansoni cytochrome P450 0.0019 0.0003 0.0003
Echinococcus multilocularis serotonin receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis protein patched 0.0042 0.0019 0.0019
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0049 0.0024 0.0586
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0022 0.0022
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0003 0.0036
Schistosoma mansoni ran 0.0022 0.0005 0.0005
Echinococcus granulosus lysine specific demethylase 6a 0.0042 0.0019 0.0019
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0019 0.0019
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0016 0.0381
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0091 0.0053 0.0053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0049 0.0024 0.0586
Echinococcus granulosus expressed protein 0.0404 0.0272 0.0272
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0002 0.0002
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0027 0.0027
Echinococcus granulosus Smad4 0.0042 0.0019 0.0019
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Brugia malayi Isocitrate dehydrogenase 0.0096 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0091 0.0053 0.0053
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0259 0.0171 0.4193
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0022 0.0448
Schistosoma mansoni adenoreceptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Echinococcus multilocularis inositol monophosphatase 1 0.0117 0.0071 0.0071
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0163 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0017 0.041
Toxoplasma gondii LsmAD domain-containing protein 0.013 0.0081 0.0081
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0185 0.0119 0.3042
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0004 0.0005
Schistosoma mansoni nuclear receptor 0.0077 0.0043 0.0043
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0002 0.0003
Echinococcus multilocularis kelch ECH associated protein 1 0.0095 0.0056 0.0056
Echinococcus granulosus jun protein 0.0084 0.0048 0.0048
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0002 0.0002
Brugia malayi CXXC zinc finger family protein 0.0058 0.0031 0.0031
Brugia malayi nuclear hormone receptor 0.0163 0.0104 0.0104
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0069 0.0038 0.0038
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Echinococcus multilocularis caspase 8 0.0091 0.0053 0.0053
Brugia malayi ecdysone receptor 0.0077 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0019 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0049 0.1202
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0003 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0196
Schistosoma mansoni dep domain containing protein 0.0018 0.0002 0.0002
Leishmania major trypanothione reductase 0.0135 0.0084 0.0113
Echinococcus multilocularis thioredoxin glutathione reductase 0.0136 0.0084 0.0084
Brugia malayi Nuclear hormone receptor-like 1 0.0086 0.005 0.005
Loa Loa (eye worm) dehydrogenase 0.002 0.0004 0.0004
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0002 0.0002
Plasmodium vivax DNA topoisomerase 3, putative 0.0259 0.0171 0.0171
Loa Loa (eye worm) DR-78 0.0077 0.0043 0.0043
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0002 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0102
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Mycobacterium tuberculosis Conserved protein 0.0026 0.0008 0.0162
Plasmodium falciparum ABC transporter G family member 2 0.002 0.0004 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0002 0.0002
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0029 0.0029
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.002 0.0004 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis DNA topoisomerase II, putative 0.0059 0.0031 0.0755
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0003 0.0036
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0006 0.0008
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0005 0.0005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0117 0.0071 0.1751
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0004 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0004 0.0004
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0005 0.0005
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0059 0.0031 0.0031
Leishmania major alpha glucosidase II subunit, putative 0.0049 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0163 0.0104 0.0104
Echinococcus multilocularis cysteine protease 0.0018 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0005 0.0005
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0004 0.0005
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Schistosoma mansoni zinc finger protein 0.0018 0.0002 0.0002
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0003 0.0064
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0002 0.0002
Brugia malayi CHE-14 protein 0.0042 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0035 0.0014 0.058
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0085 0.0049 0.1484
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0011 0.0011
Echinococcus multilocularis jumonji domain containing 1A 0.0042 0.0019 0.0019
Echinococcus granulosus steroid dehydrogenase 0.002 0.0004 0.0004
Toxoplasma gondii NADPH-glutathione reductase 0.0047 0.0022 0.0022
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0185 0.4543
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.006 0.008
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Brugia malayi MH2 domain containing protein 0.0019 0.0003 0.0003
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0146 0.0196
Echinococcus granulosus caspase 3 0.0149 0.0094 0.0094
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0002 0.0002
Echinococcus granulosus carbonyl reductase 1 0.002 0.0004 0.0004
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0019 0.0459
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0008 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0038 0.0051
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0004 0.0005
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0003 0.0003
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.005
Trypanosoma cruzi metacaspase, putative 0.0091 0.0053 0.0071
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0035 0.0035
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0212 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0024 0.0024
Giardia lamblia DNA topoisomerase III 0.0135 0.0084 0.2063
Loa Loa (eye worm) hypothetical protein 0.0015 0.000000080466 0.000000080466
Echinococcus multilocularis expressed conserved protein 0.0091 0.0053 0.0053
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0022 0.0022
Toxoplasma gondii histone lysine methyltransferase SET1 0.0128 0.0079 0.0079
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Trypanosoma brucei Metacaspase-4 0.0091 0.0053 0.0071
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0212 0.0138 0.0138
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0097 0.0057 0.0057
Entamoeba histolytica deoxycytidyl transferase, putative 0.0073 0.0041 0.1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0003 0.0036
Loa Loa (eye worm) pax transcription factor protein 2 0.0733 0.0502 0.0502
Loa Loa (eye worm) DNA topoisomerase III 0.0266 0.0176 0.0176
Brugia malayi Cell death protein 3 precursor 0.0175 0.0112 0.0112
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0003 0.0004
Onchocerca volvulus 0.002 0.0004 0.0073
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0002 0.0002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.003 0.0011 0.0011
Schistosoma mansoni terminal deoxycytidyl transferase 0.0073 0.0041 0.0041
Brugia malayi Smad1 0.0042 0.0019 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0018 0.0002 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0053 0.1303
Loa Loa (eye worm) thioredoxin reductase 0.0135 0.0084 0.0084
Trichomonas vaginalis ferritin, putative 0.0035 0.0014 0.0347
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0004 0.0027
Brugia malayi hypothetical protein 0.0066 0.0036 0.0036
Brugia malayi jmjC domain containing protein 0.0042 0.0019 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0073 0.0041 0.0041
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0003 0.0003
Echinococcus multilocularis Smad4 0.0042 0.0019 0.0019
Brugia malayi Melibiase family protein 0.0141 0.0088 0.0088
Echinococcus multilocularis dnaJ subfamily B 0.0833 0.0571 0.0571
Brugia malayi Cytochrome P450 family protein 0.0019 0.0003 0.0003
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0003 0.0036
Brugia malayi serine/threonine-protein kinase plk-2 0.0194 0.0125 0.0125
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0034 0.0014 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0002 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0016 0.0016
Onchocerca volvulus 0.0018 0.0002 0.0043
Leishmania major cathepsin L-like protease 0.0069 0.0038 0.0051
Onchocerca volvulus 0.0027 0.0008 0.0164
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0022 0.003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0008
Onchocerca volvulus 0.0018 0.0002 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0002 0.0002
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0266 0.0176 0.0176
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.001 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0163 0.0104 0.0104
Brugia malayi larval opioid receptor 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0016 0.0381
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.001 0.001
Schistosoma mansoni thyroid hormone receptor 0.0163 0.0104 0.0104
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0006
Schistosoma mansoni carbonyl reductase 0.002 0.0004 0.0004
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0004 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Schistosoma mansoni bromodomain containing protein 0.0018 0.0002 0.0002
Echinococcus granulosus jumonji domain containing protein 0.004 0.0017 0.0017
Toxoplasma gondii isocitrate dehydrogenase 0.0096 0.0057 0.0057
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0002 0.0043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0086 0.005 0.0067
Schistosoma mansoni dishevelled 0.0018 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0042 0.0019 0.0019
Leishmania major protein kinase, putative 0.0094 0.0055 0.0074
Schistosoma mansoni amine GPCR 0.0018 0.0002 0.0002
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0017 0.0017
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0002 0.0002
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0018 0.0002 0.0002
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.019 0.0122 0.0122
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0037 0.0037
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0027 0.0027
Schistosoma mansoni aryl hydrocarbon receptor 0.0304 0.0202 0.0202
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0009 0.0009
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0042 0.0019 0.0019
Loa Loa (eye worm) cytochrome P450 0.0019 0.0003 0.0003
Plasmodium falciparum DNA gyrase subunit B 0.0059 0.0031 0.0031
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0135 0.0084 0.0084
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0194 0.0125 0.0169
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0019 0.0019
Echinococcus granulosus jumonji domain containing 1A 0.0042 0.0019 0.0019
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0004 0.0058
Schistosoma mansoni hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi oxidoreductase 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0002 0.0042
Brugia malayi ABC transporter family protein 0.0017 0.0002 0.0002
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0004 0.009
Mycobacterium ulcerans DNA polymerase IV 0.01 0.006 0.1485
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0006 0.0007
Echinococcus multilocularis expressed protein 0.0035 0.0014 0.0014
Mycobacterium ulcerans DNA gyrase subunit B 0.0059 0.0031 0.073
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0004 0.0027
Brugia malayi Bromodomain containing protein 0.0043 0.002 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0163 0.0104 0.0104
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0042 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0002 0.0047
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0004 0.0004
Brugia malayi Globin family protein 0.0027 0.0008 0.0008
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0004 0.0005
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0037 0.0037
Schistosoma mansoni patched 1 0.0042 0.0019 0.0019
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0004 0.0058
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0000000024747 0.0000000024747
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0004 0.0004
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0194 0.0125 0.0125
Brugia malayi neuropeptide F receptor 0.0018 0.0002 0.0002
Brugia malayi Globin family protein 0.0027 0.0008 0.0008
Loa Loa (eye worm) ctsf protein 0.0018 0.0002 0.0002
Mycobacterium ulcerans oxidoreductase 0.002 0.0004 0.0027
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0163 0.0104 0.0104
Leishmania major hypothetical protein, conserved 0.0022 0.0005 0.0007
Echinococcus granulosus carbonyl reductase 1 0.002 0.0004 0.0004
Echinococcus multilocularis aryl hydrocarbon receptor 0.0103 0.0062 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Onchocerca volvulus 0.0018 0.0002 0.0043
Schistosoma mansoni hypothetical protein 0.0068 0.0037 0.0037
Giardia lamblia PHD finger protein 15 0.0029 0.001 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0053 0.1303
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.0045 0.0045
Toxoplasma gondii DNA topoisomerase I, putative 1.4333 1 1
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Brugia malayi G-protein coupled receptor 0.0018 0.0002 0.0002
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0185 0.0119 0.0119
Toxoplasma gondii oxidoreductase, putative 0.002 0.0004 0.0004
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0308 0.0205 0.5247
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0085 0.0049 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.01 0.006 0.008
Schistosoma mansoni nuclear hormone receptor 0.0163 0.0104 0.0104
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0004 0.009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0004 0.0058
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0011 0.0015
Schistosoma mansoni neuropeptide receptor 0.0018 0.0002 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.0163 0.0104 0.0104
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0091 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei ABC transporter, putative 0.002 0.0004 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.006 0.008
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0004 0.0004
Echinococcus granulosus oxidoreductase 0.002 0.0004 0.0004
Plasmodium falciparum DNA topoisomerase 2 0.0059 0.0031 0.0031
Echinococcus multilocularis 0.0056 0.0029 0.0029
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Brugia malayi Inositol-1 0.0117 0.0071 0.0071
Schistosoma mansoni ABC transporter 0.0017 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0059 0.0031 0.1415
Leishmania major glycosyl hydrolase-like protein 0.0018 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0058
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0163 0.0104 0.0104
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0074 0.0042 0.0042
Schistosoma mansoni coup transcription factor 0.0163 0.0104 0.0104
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0003 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0006 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Leishmania major hypothetical protein, conserved 0.002 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Echinococcus granulosus survival motor neuron protein 1 0.1458 0.1008 0.1008
Leishmania major DNA topoisomerase 1A 0.0259 0.0171 0.023
Schistosoma mansoni Smad4 0.0042 0.0019 0.0019
Brugia malayi RNA binding protein 0.0067 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Echinococcus multilocularis dna polymerase eta 0.0125 0.0077 0.0077
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0017 0.0017
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0004 0.0005
Leishmania major metacaspase, putative 0.0091 0.0053 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0024 0.0024
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0105 0.0063 0.1587
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0004 0.0004
Schistosoma mansoni caspase-7 (C14 family) 0.0175 0.0112 0.0112
Loa Loa (eye worm) histone methyltransferase 0.002 0.0004 0.0004
Loa Loa (eye worm) MBCTL1 0.0053 0.0027 0.0027
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0141 0.0088 0.2169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0163 0.0104 0.0104
Onchocerca volvulus 0.0067 0.0036 0.0726
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0163 0.0104 0.0104
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0038 0.0051
Plasmodium vivax vivapain-2 0.0018 0.0002 0.0002
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0004 0.0004
Trichomonas vaginalis hypothetical protein 0.0034 0.0013 0.0328
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0017 0.0017
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0003 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0096 0.0057 0.0057
Plasmodium vivax DNA gyrase subunit B, putative 0.0059 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0016 0.0381
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0059 0.0031 0.0041
Entamoeba histolytica hypothetical protein 0.0301 0.02 0.4919
Echinococcus granulosus neutral alpha glucosidase AB 0.0049 0.0024 0.0024
Plasmodium falciparum metacaspase-like protein 0.0091 0.0053 0.0053
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0009 0.0012
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0101 0.0101
Echinococcus granulosus expressed conserved protein 0.0091 0.0053 0.0053
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Trichomonas vaginalis set domain proteins, putative 0.0502 0.034 0.8352
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0085 0.0049 0.1202
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0027 0.0027
Trypanosoma cruzi DNA polymerase eta, putative 0.0074 0.0042 0.0056
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0004 0.0073
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0011 0.0015
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0004 0.0004
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0085 0.0049 0.0066
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0024 0.0586
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0025 0.0033
Entamoeba histolytica ABC transporter, putative 0.002 0.0004 0.0091
Trypanosoma brucei polo-like protein kinase 0.0194 0.0125 0.0169
Brugia malayi RNA, U transporter 1 0.0086 0.005 0.005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Onchocerca volvulus 0.002 0.0004 0.0073
Loa Loa (eye worm) hypothetical protein 0.013 0.0081 0.0081
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.002 0.0004 0.0073
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0018 0.0002 0.0059
Leishmania major DNA damage repair protein, putative 0.0023 0.0006 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.0122 0.3109
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0077 0.0043 0.0043
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0002 0.0002
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Toxoplasma gondii aldehyde dehydrogenase 0.019 0.0122 0.0122
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0004 0.0005
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.5172 0.3602 0.4847
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0017 0.041
Echinococcus granulosus Nuclear hormone receptor HR96 0.0077 0.0043 0.0043
Loa Loa (eye worm) nuclear receptor NHR-67 0.0077 0.0043 0.0043
Leishmania major hypothetical protein, conserved 0.002 0.0004 0.0005
Echinococcus granulosus carbonyl reductase 1 0.002 0.0004 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0163 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0004 0.0005
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0003 0.0004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0004 0.0058
Trypanosoma brucei PAB1-binding protein , putative 0.013 0.0081 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0004 0.0027
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0002 0.0057
Trypanosoma brucei metacaspase MCA2 0.0091 0.0053 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0163 0.0104 0.0104
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni nuclear receptor nhr-48 0.0077 0.0043 0.0043
Brugia malayi AKH receptor 0.0018 0.0002 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0004 0.0058
Schistosoma mansoni tsg101-related 0.0058 0.003 0.003
Echinococcus granulosus muscleblind protein 0.0619 0.0422 0.0422
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0035 0.0035
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0002 0.0002
Brugia malayi Retinol dehydrogenase 12 0.002 0.0004 0.0004
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0182 0.0117 0.0117
Loa Loa (eye worm) steroid hormone receptor 0.0163 0.0104 0.0104
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0342 0.0229 0.5871
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis inositol monophosphatase, putative 0.0117 0.0071 0.1751
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0163 0.0104 0.0104
Trypanosoma cruzi DNA topoisomerase III, putative 0.0135 0.0084 0.0113
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0085 0.0049 0.0049
Plasmodium falciparum histone acetyltransferase GCN5 0.0163 0.0103 0.0103
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0004 0.0058
Leishmania major DNA polymerase kappa, putative 0.008 0.0045 0.0061
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0117 0.0071 0.1751
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0002 0.0002
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Schistosoma mansoni Smad4 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0289 0.0192 0.0192
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0163 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0026
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis transfer RNA-Lys 0.0219 0.0143 0.0143
Echinococcus multilocularis kelch ECH associated protein 1 0.0095 0.0056 0.0056
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0002 0.0002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0217 0.0141 0.0141
Brugia malayi Serotonin receptor 0.0018 0.0002 0.0002
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.024 0.0157 0.0157
Brugia malayi Importin beta-1 subunit 0.003 0.0011 0.0011
Loa Loa (eye worm) DNA topoisomerase I 1.4333 1 1
Brugia malayi acetyltransferase, GNAT family protein 0.0604 0.0411 0.0411
Echinococcus granulosus allatostatin A receptor 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0003 0.0004
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0002 0.0002
Onchocerca volvulus 0.002 0.0004 0.0073
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Leishmania major cytochrome p450-like protein 0.0019 0.0003 0.0004
Onchocerca volvulus 0.0018 0.0002 0.0042
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0002 0.0002
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0077 0.0043 0.0043
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0015 0.000000080466 0.000000080466
Entamoeba histolytica ankyrin repeat protein, putative 0.0015 0.0000000024747 0.000000060793
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0003 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0163 0.0104 0.0104
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0085 0.0049 0.1202
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0062 0.0033 0.0033
Echinococcus multilocularis ecdysone induced protein 78C 0.0163 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0042 0.0019 0.0019
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0022 0.003
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0179 0.0115 0.0115
Onchocerca volvulus Serine\/threonine kinase homolog 0.0194 0.0125 0.2499
Plasmodium falciparum topoisomerase I 1.4333 1 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0071 0.0096
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0004 0.009
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0212 0.0138 0.0138
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0096 0.0057 0.0057
Brugia malayi cytochrome P450 0.0019 0.0003 0.0003
Echinococcus multilocularis geminin 0.1219 0.0841 0.0841
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.001 0.0245
Brugia malayi isocitrate dehydrogenase 0.0096 0.0057 0.0057
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0086 0.005 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0077 0.0043 0.0866
Brugia malayi MH2 domain containing protein 0.0042 0.0019 0.0019
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0004 0.0004
Schistosoma mansoni alpha-glucosidase 0.0129 0.008 0.008
Onchocerca volvulus 0.0018 0.0002 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0185 0.4543
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0077 0.0043 0.0043
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0003 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0163 0.0104 0.0104
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0259 0.0171 0.4193
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0002 0.0002
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.5172 0.3602 0.4847
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Onchocerca volvulus 0.0027 0.0008 0.0164
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0016 0.0016
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0057 0.0057
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0163 0.0104 0.0104
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0004 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0059
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0005 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0003 0.0036
Schistosoma mansoni ferritin 0.0035 0.0014 0.0014
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0034 0.0014 0.0014
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0009 0.0009
Schistosoma mansoni smad1 5 8 and 0.0042 0.0019 0.0019
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0024 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0007 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0086 0.005 0.005
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Echinococcus multilocularis rho GTPase activating protein 20 0.0266 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0015 0.000000080466 0.000000080466
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0004 0.0005
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0003 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0002 0.0002
Echinococcus granulosus insulin receptor 0.0058 0.003 0.003
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0006 0.0007
Schistosoma mansoni DNA topoisomerase II 0.0059 0.0031 0.0031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Schistosoma mansoni biogenic amine receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0003 0.0064
Schistosoma mansoni hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0103 0.0062 0.0062
Brugia malayi PXA domain containing protein 0.0021 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0022 0.0503
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0103 0.0062 0.1228
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0096 0.0057 0.0057
Echinococcus granulosus histone acetyltransferase KAT2B 0.0177 0.0114 0.0114
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0001 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Schistosoma mansoni smad1 5 8 and 0.0042 0.0019 0.0019
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0002 0.0002
Trypanosoma cruzi trypanothione reductase, putative 0.0135 0.0084 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0163 0.0104 0.0104
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0091 0.0053 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0102
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0003 0.0004
Echinococcus granulosus snurportin 1 0.0324 0.0216 0.0216
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0003
Echinococcus multilocularis caspase 3 0.0149 0.0094 0.0094
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0059 0.0031 0.0031
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Giardia lamblia Hypothetical protein 0.002 0.0004 0.009
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0004 0.0058
Echinococcus granulosus cpg binding protein 0.0062 0.0033 0.0033
Onchocerca volvulus 0.0018 0.0002 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Echinococcus granulosus caspase 0.024 0.0157 0.0157
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0004 0.0004
Trypanosoma cruzi metacaspase 5, putative 0.0091 0.0053 0.0071
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0002 0.0002
Onchocerca volvulus Globin homolog 0.0027 0.0008 0.0164
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0024 0.0581
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0004 0.0004
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0058
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0004 0.0027
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0008 0.001
Echinococcus granulosus phd:f box containing protein 0.0042 0.0019 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0002 0.0002
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0016 0.0016
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0004 0.0005
Plasmodium falciparum glutathione reductase 0.0135 0.0084 0.0084
Echinococcus granulosus single minded 2 0.0219 0.0143 0.0143
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0163 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi nuclear hormone receptor family member odr-7 0.0077 0.0043 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0006 0.0006
Brugia malayi mbt repeat family protein 0.0047 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0085 0.0049 0.0049
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0163 0.0104 0.0104
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Schistosoma mansoni amine GPCR 0.0018 0.0002 0.0002
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0005 0.0005
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni apoferritin-2 0.0035 0.0014 0.0014
Onchocerca volvulus 0.0297 0.0197 0.3935
Onchocerca volvulus 0.0058 0.0031 0.0608
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0308 0.0205 0.5264
Schistosoma mansoni multidrug resistance protein 0.0069 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Plasmodium vivax vivapain-2 0.0018 0.0002 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0163 0.0104 0.0104
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.0024 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0161 0.0102 0.0102
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.0024 0.0581
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Trypanosoma brucei AAA ATPase, putative 0.0015 0.000000080466 0.00000010828
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0135 0.0084 0.2137
Plasmodium falciparum ataxin-2 like protein, putative 0.013 0.0081 0.0081
Brugia malayi Protein kinase domain containing protein 0.0182 0.0117 0.0117
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0018 0.0002 0.0003
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0004 0.0005
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0004 0.009
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.002 0.0004 0.0005
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.007 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0053 0.1303
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Echinococcus multilocularis serotonin receptor 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0049 0.1202
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei trypanothione reductase 0.0135 0.0084 0.0113
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0002 0.0002
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0003 0.0004
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Echinococcus granulosus expressed protein 0.0035 0.0014 0.0014
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Brugia malayi Cathepsin L-like precursor 0.0018 0.0002 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0598 0.0407 1
Schistosoma mansoni ferritin light chain 0.0035 0.0014 0.0014
Loa Loa (eye worm) dehydrogenase 0.002 0.0004 0.0004
Echinococcus granulosus fmrfamide receptor 0.0018 0.0002 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0096 0.0057 0.0057
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.0096 0.0057 0.0057
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0059
Schistosoma mansoni jumonji/arid domain-containing protein 0.0161 0.0102 0.0102
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0023
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0077 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.007 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0049 0.0024 0.0586
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0003 0.0036
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0091 0.0053 0.0053
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0085 0.0049 0.1202
Brugia malayi bHLH-PAS transcription factor 0.0219 0.0143 0.0143
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0067 0.0037 0.0037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Toxoplasma gondii isocitrate dehydrogenase 0.0096 0.0057 0.0057
Leishmania major hypothetical protein, conserved 0.0224 0.0146 0.0196
Schistosoma mansoni tyrosine kinase 0.0096 0.0057 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.017 0.0109 0.2666
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0004 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0197
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0002 0.0002
Schistosoma mansoni globin X 0.0027 0.0008 0.0008
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0004 0.0004
Onchocerca volvulus Bile acid receptor homolog 0.0163 0.0104 0.2066
Mycobacterium tuberculosis Probable reductase 0.0308 0.0205 0.5264
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi metacaspase 5, putative 0.0091 0.0053 0.0071
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0004 0.0004
Treponema pallidum NADH oxidase 0.0047 0.0022 0.0488
Schistosoma mansoni amine GPCR 0.0018 0.0002 0.0002
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0009 0.022
Brugia malayi hypothetical protein 0.1021 0.0702 0.0702
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0004 0.0004
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0001 0.0001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0292 0.0194 0.4956
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0028
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0008 0.0008
Echinococcus multilocularis lysine specific demethylase 5A 0.0158 0.01 0.01
Mycobacterium ulcerans hypothetical protein 0.0026 0.0008 0.0131
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0007 0.0168
Trichomonas vaginalis adenylate cyclase, putative 0.0085 0.0049 0.1202
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.001 0.001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0212 0.0138 0.0138
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.057 0.0388 1
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0185 0.4543
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0057 0.141
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.01 0.006 0.1469
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0009 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Echinococcus granulosus aryl hydrocarbon receptor 0.0103 0.0062 0.0062
Leishmania major mitochondrial DNA topoisomerase II 0.0059 0.0031 0.0041
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0037 0.0912
Brugia malayi sulfakinin receptor protein 0.0018 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0048 0.0048
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.0102
Trypanosoma brucei DNA polymerase eta, putative 0.0125 0.0077 0.0103
Brugia malayi nuclear receptor RXR 0.0077 0.0043 0.0043
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0022 0.0022
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0004 0.0005
Echinococcus granulosus epidermal growth factor receptor 0.0097 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0004 0.0058
Brugia malayi Uncoordinated protein 44 0.0016 0.0001 0.0001
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0002 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Mycobacterium ulcerans hypothetical protein 0.0023 0.0006 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0163 0.0104 0.0104
Onchocerca volvulus 0.0066 0.0036 0.0713
Trypanosoma cruzi ATP-binding cassette protein, putative 0.002 0.0004 0.0005
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0004 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0042 0.0019 0.0026
Echinococcus multilocularis survival motor neuron protein 1 0.1458 0.1008 0.1008
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0035 0.0014 0.033
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0038 0.0051
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0185 0.4543
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Echinococcus multilocularis Ankyrin 0.0016 0.0001 0.0001
Schistosoma mansoni RAR-like nuclear receptor 0.0163 0.0104 0.0104
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0004 0.0004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0016 0.0016
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0059 0.0031 0.0695
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0018 0.0002 0.0059
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0004 0.0005
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0057 0.0057
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Trypanosoma brucei metacaspase MCA3 0.0091 0.0053 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0163 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0047 0.0022 0.0022
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0091 0.0053 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0026
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0037 0.0037
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0069 0.0038 0.0051
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0085 0.0049 0.0066
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0006 0.0006
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0058 0.003 0.003
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0029 0.0029
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0117 0.0071 0.0096
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0059 0.0031 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0053 0.1303
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0038 0.0051
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0059 0.0031 0.0031
Trypanosoma brucei membrane transporter protein, putative 0.0069 0.0038 0.0051
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0004 0.0004
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0003 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.01 0.006 0.008
Echinococcus multilocularis epidermal growth factor receptor 0.0097 0.0057 0.0057
Brugia malayi glutathione reductase 0.0135 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.003 0.0011 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0196
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0057 0.1401
Echinococcus multilocularis sex peptide receptor 0.0018 0.0002 0.0002
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0004 0.0005
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.002 0.0004 0.0023
Echinococcus multilocularis nuclear receptor nhr 48 0.0077 0.0043 0.0043
Loa Loa (eye worm) glutathione reductase 0.0135 0.0084 0.0084
Schistosoma mansoni histamine h1 receptor 0.0018 0.0002 0.0002
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0141 0.0088 0.0088
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0077 0.0043 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0003 0.0036
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0002 0.0002
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0003 0.0004
Schistosoma mansoni survival motor neuron protein 0.0297 0.0197 0.0197
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0069 0.0038 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0004 0.0102
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0002 0.0002
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) acetyltransferase 0.0604 0.0411 0.0411
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Plasmodium vivax ABC transporter G family member 2, putative 0.002 0.0004 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0022 0.0022
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0004 0.0058
Loa Loa (eye worm) fibroinase 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0016
Onchocerca volvulus 0.0018 0.0002 0.0043
Schistosoma mansoni tyrosine kinase 0.0097 0.0057 0.0057
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.005 0.0025 0.0033
Trichomonas vaginalis maltase-glucoamylase, putative 0.0018 0.0002 0.0059
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.006 0.008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.0022 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0002 0.0057
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0005 0.0007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0141 0.0088 0.0088
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0002 0.0002
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0042 0.0019 0.0026
Loa Loa (eye worm) nuclear hormone receptor 0.0077 0.0043 0.0043
Onchocerca volvulus 0.0018 0.0002 0.0043
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0004 0.0004
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3361 0.2337 0.2337
Onchocerca volvulus 0.002 0.0004 0.0073
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0001 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0047 0.0022 0.003
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0085 0.0049 0.1202
Brugia malayi tailless protein 0.0077 0.0043 0.0043
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0177 0.0114 0.0114
Echinococcus multilocularis ferritin 0.0035 0.0014 0.0014
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0003 0.0004
Mycobacterium ulcerans oxidoreductase 0.002 0.0004 0.0027
Plasmodium vivax JmjC domain containing protein 0.0042 0.0019 0.0019
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.002 0.0004 0.0028
Mycobacterium tuberculosis Conserved hypothetical protein 0.0073 0.0041 0.1017
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0361 0.0242 0.0242
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0019 0.0019
Trypanosoma brucei MATE efflux family protein, putative 0.0069 0.0038 0.0051
Onchocerca volvulus 0.002 0.0004 0.0073
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0003 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0022 0.003
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.017 0.0109 0.2666
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0002 0.0002
Brugia malayi RE15519p 0.0018 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0053 0.1303
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni myoglobin 1 0.0027 0.0008 0.0008
Schistosoma mansoni biogenic amine receptor 0.0018 0.0002 0.0002
Plasmodium falciparum metacaspase 1 0.0091 0.0053 0.0053
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0005 0.0007
Entamoeba histolytica DNA topoisomerase II, putative 0.0059 0.0031 0.0755
Onchocerca volvulus 0.002 0.0004 0.0073
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0163 0.0104 0.0104
Brugia malayi hypothetical protein 0.0027 0.0008 0.0008
Brugia malayi hypothetical protein 0.013 0.0081 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0026
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0002 0.0002
Schistosoma mansoni opsin-like receptor 0.0018 0.0002 0.0002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0141 0.0088 0.0088
Onchocerca volvulus 0.0027 0.0008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Trypanosoma cruzi metacaspase, putative 0.0091 0.0053 0.0071
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0004 0.009
Mycobacterium tuberculosis Probable oxidoreductase 0.0342 0.0229 0.5885
Toxoplasma gondii bromodomain-containing protein 0.0015 0.0000000024747 0.0000000024747
Echinococcus granulosus thioredoxin glutathione reductase 0.0136 0.0084 0.0084
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0096 0.0057 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0003 0.0036
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0259 0.0171 0.023
Echinococcus granulosus g protein coupled receptor 0.0018 0.0002 0.0002
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0177 0.0114 0.0114
Loa Loa (eye worm) TK/INSR protein kinase 0.0058 0.003 0.003
Brugia malayi Cytochrome P450 family protein 0.0046 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0163 0.0104 0.0104
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0059 0.0031 0.0613
Schistosoma mansoni aldehyde dehydrogenase 0.019 0.0122 0.0122
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0002 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0047 0.0022 0.0022
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0185 0.0119 0.016
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0085 0.0049 0.1202
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0004 0.0027
Echinococcus multilocularis peregrin 0.0043 0.002 0.002
Echinococcus granulosus tumor protein p63 0.0366 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0197
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Echinococcus multilocularis DNA topoisomerase 1 1.4333 1 1
Loa Loa (eye worm) Smad1 0.0042 0.0019 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0003 0.0036
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Chlamydia trachomatis DNA gyrase subunit B 0.0059 0.0031 0.0468
Brugia malayi Globin family protein 0.0027 0.0008 0.0008
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0259 0.0171 0.4361
Brugia malayi Flap endonuclease-1 0.0028 0.0009 0.0009
Trypanosoma brucei hypothetical protein, conserved 0.0224 0.0146 0.0196
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0004 0.0004
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0308 0.0205 0.5264
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0004 0.0004
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0004 0.0005
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0342 0.0229 0.5885
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0117 0.0071 0.0071
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0047 0.0022 0.0022
Echinococcus granulosus dna polymerase kappa 0.01 0.006 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Echinococcus multilocularis oxidoreductase 0.002 0.0004 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.0086 0.005 0.005
Schistosoma mansoni smad 0.0042 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0003 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0004 0.0058
Plasmodium vivax SET domain containing protein 0.0018 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0017 0.041
Plasmodium falciparum thioredoxin reductase 0.0047 0.0022 0.0022
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0004 0.0004
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0004 0.009
Echinococcus multilocularis snurportin 1 0.0324 0.0216 0.0216
Trypanosoma brucei unspecified product 0.0094 0.0055 0.0074
Entamoeba histolytica bromodomain-containing protein 0.0015 0.000000024518 0.00000060229
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0003 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0002 0.0002
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0007 0.0009
Leishmania major DNA polymerase kappa, putative 0.0023 0.0006 0.0007
Brugia malayi N-terminal motif family protein 0.0361 0.0242 0.0242
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0024 0.0586
Echinococcus granulosus death domain containing protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni ran 0.0022 0.0005 0.0005
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0135 0.0084 0.0084
Giardia lamblia Reductase, putative 0.002 0.0004 0.009
Plasmodium falciparum phd finger protein, putative 0.0029 0.001 0.001
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0004 0.009
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Onchocerca volvulus 0.0018 0.0002 0.0043
Echinococcus granulosus ferritin 0.0035 0.0014 0.0014
Echinococcus granulosus flap endonuclease 1 0.0028 0.0009 0.0009
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0105 0.0063 0.1557
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0002 0.0002
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0292 0.0194 0.4974
Onchocerca volvulus Alhambra homolog 0.0029 0.001 0.0192
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0027 0.0008 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.01 0.006 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.0024 0.0581
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0002 0.0057
Brugia malayi nuclear receptor RXR 0.0086 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0005 0.0007
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0002 0.0002
Trypanosoma brucei glucosidase, putative 0.0049 0.0024 0.0032
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0163 0.0104 0.0104
Onchocerca volvulus Huntingtin homolog 0.0384 0.0258 0.5134
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0047 0.0022 0.0022
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.0003
Echinococcus multilocularis lysine specific demethylase 6a 0.0042 0.0019 0.0019
Onchocerca volvulus 0.0018 0.0002 0.0043
Leishmania major cytochrome p450-like protein 0.0046 0.0022 0.003
Plasmodium vivax topoisomerase I, putative 1.4333 1 1
Brugia malayi Dopamine receptor protein 2 0.0018 0.0002 0.0002
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0005 0.0005
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0059 0.0031 0.0031
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0004 0.0004
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0004 0.009
Trypanosoma brucei DNA topoisomerase ii 0.0059 0.0031 0.0041
Schistosoma mansoni hypothetical protein 0.0027 0.0008 0.0008
Brugia malayi Cytochrome P450 family protein 0.0039 0.0017 0.0017
Onchocerca volvulus 0.0018 0.0002 0.0043
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0004 0.0004
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Brugia malayi hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi Probable DNA topoisomerase II 0.0059 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.1021 0.0702 0.0702
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0058 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0004 0.0027
Loa Loa (eye worm) TK/EGFR protein kinase 0.018 0.0115 0.0115
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0002 0.0002
Trichomonas vaginalis bromodomain-containing protein, putative 0.0177 0.0114 0.2791
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0035 0.0035
Trypanosoma cruzi polo-like protein kinase, putative 0.0194 0.0125 0.0169
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0002 0.0002
Plasmodium vivax ataxin-2 like protein, putative 0.013 0.0081 0.0081
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0185 0.0119 0.302
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0018 0.0002 0.0003
Brugia malayi nuclear receptor NHR-88 0.0163 0.0104 0.0104
Toxoplasma gondii melibiase subfamily protein 0.0212 0.0138 0.0138
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0002 0.0002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0003 0.0004
Onchocerca volvulus 0.002 0.0004 0.0073
Echinococcus granulosus ATP binding cassette sub family G 0.002 0.0004 0.0004
Chlamydia trachomatis DNA topoisomerase I 0.0303 0.0201 1
Brugia malayi bZIP transcription factor family protein 0.0084 0.0048 0.0048
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0004 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0135 0.0084 0.0084
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0101 0.0101
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.0003
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0059 0.0031 0.0613
Trypanosoma brucei unspecified product 0.005 0.0025 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Brugia malayi jmjC domain containing protein 0.0161 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.028 0.0185 0.0185
Schistosoma mansoni smad1 5 8 and 0.0042 0.0019 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0057 0.1401
Brugia malayi hypothetical protein 0.0018 0.0002 0.0002
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0163 0.0104 0.0104
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0005 0.0007
Trypanosoma brucei membrane transporter protein, putative 0.0069 0.0038 0.0051
Schistosoma mansoni myosin xvIII 0.0018 0.0002 0.0002
Toxoplasma gondii thioredoxin reductase 0.0135 0.0084 0.0084
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.001
Loa Loa (eye worm) globin family protein 0.0027 0.0008 0.0008
Giardia lamblia Fructose-bisphosphate aldolase 0.0598 0.0407 1
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0002 0.0002
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0047 0.0022 0.0513
Onchocerca volvulus 0.0056 0.0029 0.0576
Mycobacterium leprae Probable oxidoreductase 0.002 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0163 0.0104 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0004 0.0005
Echinococcus granulosus epidermal growth factor receptor 0.018 0.0115 0.0115
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0308 0.0205 0.5264
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0016 0.0021
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0047 0.0022 0.0022
Trichomonas vaginalis sucrase-isomaltase, putative 0.0049 0.0024 0.0586
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0003 0.0036
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Echinococcus granulosus mothers against decapentaplegic 5 0.0042 0.0019 0.0019
Onchocerca volvulus Sepiapterin reductase homolog 0.002 0.0004 0.0073
Brugia malayi Cytochrome P450 family protein 0.0046 0.0022 0.0022
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0047 0.0022 0.0993
Schistosoma mansoni netrin receptor unc5 0.0016 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0026 0.0008 0.0131
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.002 0.0004 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0118 0.2894
Loa Loa (eye worm) hypothetical protein 0.0619 0.0422 0.0422
Schistosoma mansoni intermediate filament proteins 0.0056 0.0029 0.0029
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0004 0.0058
Loa Loa (eye worm) hypothetical protein 0.0619 0.0422 0.0422
Schistosoma mansoni jumonji domain containing protein 0.0042 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.0025 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0163 0.0104 0.0104
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0004 0.0058
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0077 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Trypanosoma brucei DNA topoisomerase IB, large subunit 1.0655 0.7431 1
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0004 0.0027
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0009 0.0009
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0002 0.0047
Schistosoma mansoni jumonji domain containing protein 0.0198 0.0128 0.0128
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0016 0.0381
Brugia malayi Dopamine receptor 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.005
Trypanosoma brucei unspecified product 0.005 0.0025 0.0033
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0004 0.0005
Echinococcus granulosus DNA topoisomerase 1 1.4333 1 1
Brugia malayi Muscleblind-like protein 0.0619 0.0422 0.0422
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0002 0.0002
Giardia lamblia DNA damage repair protein 0.0023 0.0006 0.0135
Onchocerca volvulus Protein cycle homolog 0.0018 0.0002 0.0047
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi Steroid receptor seven-up type 2 0.0163 0.0104 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0002 0.0002
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Toxoplasma gondii Alpha-galactosidase 0.003 0.0011 0.0011
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0598 0.0407 1
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0024 0.0032
Giardia lamblia ABC transporter 0.002 0.0004 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Schistosoma mansoni hypothetical protein 0.1219 0.0841 0.0841
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0189 0.0122 0.0122
Leishmania major protein kinase, putative 0.0086 0.005 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0008 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Echinococcus multilocularis mothers against decapentaplegic 5 0.0042 0.0019 0.0019
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0101 0.0101
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0004 0.0005
Schistosoma mansoni short chain dehydrogenase 0.002 0.0004 0.0004
Echinococcus granulosus lamin dm0 0.0056 0.0029 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0037 0.0037
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0004 0.0004
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0017 0.0023
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0008 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0163 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Onchocerca volvulus 0.0027 0.0008 0.0164
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.0045 0.0045
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0004 0.0004
Toxoplasma gondii DNA topoisomerase 2, putative 0.0059 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0077 0.0043 0.0043
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0004 0.0004
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0004
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0059 0.0031 0.0031
Echinococcus granulosus smad 0.0042 0.0019 0.0019
Brugia malayi steroid hormone receptor 0.0163 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0002 0.0057
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0053 0.1303
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0125 0.0077 0.0077
Leishmania major short chain dehydrogenase-like protein 0.002 0.0004 0.0005
Echinococcus multilocularis Kelch repeat type 1 0.0095 0.0056 0.0056
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.0024 0.0024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.0024 0.0024
Onchocerca volvulus 0.0047 0.0022 0.0448
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0008 0.0162
Treponema pallidum fructose-bisphosphate aldolase 0.0598 0.0407 1
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0022 0.0022
Brugia malayi nuclear receptor NHR-88 0.0077 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.004 0.0018 0.0018
Leishmania major hypothetical protein, conserved 0.002 0.0004 0.0005
Entamoeba histolytica hypothetical protein 0.0021 0.0004 0.0102
Schistosoma mansoni lamin 0.0056 0.0029 0.0029
Echinococcus multilocularis epidermal growth factor receptor 0.018 0.0115 0.0115
Onchocerca volvulus 0.0018 0.0002 0.0043
Schistosoma mansoni importin beta-1 0.003 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0004 0.0004
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0047 0.0022 0.003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0004 0.0004
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0002 0.0002
Echinococcus multilocularis ATP binding cassette sub family G 0.002 0.0004 0.0004
Trypanosoma brucei DNA topoisomerase IA, putative 0.0259 0.0171 0.023
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0041 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.013 0.0081 0.0109
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0002 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0002 0.0002
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.006 0.008
Loa Loa (eye worm) hypothetical protein 0.0051 0.0025 0.0025
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0117 0.0071 0.1751
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0022 0.003
Brugia malayi PHD-finger family protein 0.0029 0.001 0.001
Trypanosoma brucei metacaspase 0.0091 0.0053 0.0071
Plasmodium vivax hypothetical protein, conserved 0.002 0.0004 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0042 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.001 0.0245
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0004 0.0004
Schistosoma mansoni DNA topoisomerase type I 1.4333 1 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0038 0.0051
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0004 0.0058
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.0002 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0018 0.0002 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) transcription factor SMAD2 0.061 0.0416 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0008 0.0197
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.0024 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303
Echinococcus granulosus somatostatin receptor 0.0018 0.0002 0.0002
Schistosoma mansoni jumonji/arid domain-containing protein 0.0161 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0384 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0005 0.0005
Entamoeba histolytica acetyltransferase, GNAT family 0.0163 0.0103 0.2538
Schistosoma mansoni hypothetical protein 0.0297 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0224 0.0146 0.0196
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0212 0.0138 0.0138
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0002 0.0002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0004 0.0027
Schistosoma mansoni jun-related protein 0.0068 0.0037 0.0037
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0047 0.0022 0.0022
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0004 0.0005
Echinococcus granulosus serotonin receptor 0.0018 0.0002 0.0002
Brugia malayi photoreceptor-specific nuclear receptor 0.1133 0.0781 0.0781
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0035 0.0014 0.033
Schistosoma mansoni nuclear hormone receptor 0.0077 0.0043 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0004 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.0022 0.003
Echinococcus granulosus lamin 0.0056 0.0029 0.0029
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0194 0.0125 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0004 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.0024 0.0024
Brugia malayi hypothetical protein 0.0301 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0324 0.0216 0.0216
Echinococcus multilocularis cpg binding protein 0.0062 0.0033 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0002 0.0002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0163 0.0104 0.0104
Chlamydia trachomatis DNA gyrase subunit B 0.0059 0.0031 0.0468
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0047 0.0022 0.0542
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0024 0.0024
Toxoplasma gondii DNA topoisomerase family protein 0.0259 0.0171 0.0171
Schistosoma mansoni kinase 0.0099 0.0059 0.0059
Schistosoma mansoni inositol monophosphatase 0.0117 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0082 0.0047 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0004 0.0004
Schistosoma mansoni amine GPCR 0.0018 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0125 0.308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0024 0.0581
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0004 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0002 0.0057
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0004
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0097 0.0057 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.028 0.0185 0.4543
Onchocerca volvulus 0.0018 0.0002 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0038 0.0051
Schistosoma mansoni nuclear hormone receptor 0.0077 0.0043 0.0043
Loa Loa (eye worm) oxidoreductase 0.002 0.0004 0.0004
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0085 0.0049 0.0066
Loa Loa (eye worm) hypothetical protein 0.0175 0.0112 0.0112
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0002 0.0002
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0004 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0032 0.0032
Schistosoma mansoni carbonyl reductase 0.002 0.0004 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0015 0.0367
Onchocerca volvulus 0.0219 0.0143 0.2849
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.002 0.0004 0.0005
Onchocerca volvulus Cell death protein 3 homolog 0.0175 0.0112 0.2235
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0023 0.0006 0.0006
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.002 0.0004 0.0004
Leishmania major dehydrogenase-like protein 0.002 0.0004 0.0005
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0004 0.0058
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0004 0.0005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0035 0.0035
Brugia malayi hypothetical protein 0.007 0.0038 0.0038
Trypanosoma cruzi metacaspase, putative 0.0091 0.0053 0.0071
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0091 0.0053 0.1303

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 22 nM Inhibition of tyrosine kinase activity of Epidermal growth factor receptor from human A431 cells ChEMBL. 8632415
IC50 (binding) = 22 nM Inhibition of tyrosine kinase activity of Epidermal growth factor receptor from human A431 cells ChEMBL. 8632415

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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