Detailed information for compound 307419

Basic information

Technical information
  • TDR Targets ID: 307419
  • Name: 5-[(4-methoxyphenyl)methylsulfanyl]-1,3,4-thi adiazol-2-amine
  • MW: 253.344 | Formula: C10H11N3OS2
  • H donors: 1 H acceptors: 2 LogP: 2.33 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CSc1nnc(s1)N
  • InChi: 1S/C10H11N3OS2/c1-14-8-4-2-7(3-5-8)6-15-10-13-12-9(11)16-10/h2-5H,6H2,1H3,(H2,11,12)
  • InChiKey: INEOZHDEAZZDAA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-[(4-methoxyphenyl)methylthio]-1,3,4-thiadiazol-2-amine
  • [5-(p-anisylthio)-1,3,4-thiadiazol-2-yl]amine
  • [5-[(4-methoxybenzyl)thio]-1,3,4-thiadiazol-2-yl]amine
  • Oprea1_491091
  • ST006234
  • ZINC00036105

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0047 0.0433 0.0564
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0301 0.0445
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0143 0.1653 0.1633
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0107
Onchocerca volvulus 0.0055 0.054 0.094
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Leishmania major cathepsin L-like protease 0.0016 0.0051 0.0142
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0094 0.0094
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0288 0.0676
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0081 0.0867 0.1161
Schistosoma mansoni glutamate receptor NMDA 0.0015 0.0033 0.001
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0288 0.4259
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0063 0.0645 0.1805
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.3492 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0319 0.0407
Brugia malayi PAS domain containing protein 0.0048 0.0445 0.058
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0015 0.0033 0.0033
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0076 0.0116
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0288 0.0503
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.1023 0.1002
Loa Loa (eye worm) hypothetical protein 0.0038 0.0319 0.0472
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0063 0.0645 0.1124
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0077 0.0077
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0041 0.0041
Brugia malayi Cathepsin L-like precursor 0.0016 0.0051 0.0038
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0094 0.0097
Schistosoma mansoni regulator of G protein signaling 0.002 0.0094 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Loa Loa (eye worm) hypothetical protein 0.0047 0.0433 0.0641
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Echinococcus granulosus nmda type glutamate receptor 0.0054 0.0519 0.0519
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0288 0.0503
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0601 0.0579
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0094 0.0094
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0356 0.0997
Echinococcus granulosus cathepsin l1 0.0016 0.0051 0.0051
Echinococcus multilocularis neuropeptide s receptor 0.0461 0.5665 0.5665
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0087 0.0941 0.1393
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0333 0.4884
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0088 0.0959 0.1289
Echinococcus multilocularis glutamate receptor 2 0.0015 0.0033 0.0033
Brugia malayi Cation transporter family protein 0.0018 0.0077 0.0074
Brugia malayi hypothetical protein 0.0015 0.0036 0.0017
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0094 0.0097
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0088 0.0959 0.0959
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0077 0.0074
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.3492 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0088 0.0959 0.0938
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0094 0.0094
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0301 0.0778
Onchocerca volvulus 0.0018 0.0077 0.0135
Onchocerca volvulus 0.0042 0.037 0.0644
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0051 0.0074
Mycobacterium ulcerans hypothetical protein 0.0107 0.1199 0.3572
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0077 0.0077
Loa Loa (eye worm) ctsf protein 0.0016 0.0051 0.0075
Loa Loa (eye worm) hypothetical protein 0.0035 0.0288 0.0427
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0051 0.0241
Loa Loa (eye worm) hypothetical protein 0.0543 0.6696 0.9907
Schistosoma mansoni hypothetical protein 0.0035 0.0288 0.0265
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0076 0.0133
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0087 0.0941 0.0941
Schistosoma mansoni axis inhibition protein axin 0.002 0.0094 0.0071
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.054 0.0711
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.0959 0.0959
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0055 0.054 0.0799
Onchocerca volvulus 0.0035 0.0288 0.0502
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0081 0.0867 0.0867
Onchocerca volvulus 0.0016 0.0051 0.0088
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0035 0.0288 0.0427
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0109 0.1215 0.1215
Schistosoma mansoni hypothetical protein 0.0081 0.0867 0.0845
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0557 0.0824
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Schistosoma mansoni ap endonuclease 0.0018 0.0076 0.0053
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0119 0.1352 0.1352
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0051 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1609 0.4503
Schistosoma mansoni organic anion transporter 0.0055 0.054 0.0518
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0301 0.0301
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0088 0.0959 0.1419
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.0077 0.0074
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0356 0.0935
Mycobacterium tuberculosis Conserved protein 0.0035 0.0288 0.0992
Loa Loa (eye worm) hypothetical protein 0.0031 0.0232 0.0343
Echinococcus multilocularis dnaJ subfamily B 0.0805 1 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0288 0.0676
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0051 0.0241
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.1609 0.4503
Plasmodium vivax amine transporter, putative 0.0015 0.0036 0.0194
Brugia malayi nuclear receptor RXR 0.0042 0.037 0.0477
Loa Loa (eye worm) hypothetical protein 0.0047 0.0433 0.0641
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0018 0.0077 0.0074
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0301 0.0301
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0015 0.0036 0.0036
Echinococcus granulosus single minded 2 0.0035 0.0288 0.0288
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0077 0.0077
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0054 0.0519 0.0519
Brugia malayi proliferating cell nuclear antigen (PCNA) 0.0063 0.0645 0.0856
Loa Loa (eye worm) nuclear hormone receptor 0.0042 0.037 0.0547
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.0077 0.0077
Brugia malayi sodium-independent organic anion transporter family protein 0.0087 0.0941 0.1264
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.1023 0.2879
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0098 0.0144
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0288 0.0992
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0042 0.037 0.037
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.054 0.054
Echinococcus multilocularis NMDA receptor 0.0015 0.0033 0.0033
Brugia malayi acetyltransferase, GNAT family protein 0.0143 0.1653 0.2244
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0088 0.0959 0.1419
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0389 0.4755 0.4755
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0319 0.0407
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0319 0.2235
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0025 0.0025
Echinococcus multilocularis geminin 0.0333 0.4051 0.4051
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0333 0.0333
Echinococcus granulosus axis inhibition protein axin 0.002 0.0094 0.0094
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0288 0.0266
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0356 0.0356
Onchocerca volvulus 0.0015 0.0036 0.0063
Loa Loa (eye worm) serotonin transporter b 0.0015 0.0036 0.0053
Loa Loa (eye worm) acetyltransferase 0.0143 0.1653 0.2445
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.037 0.037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0088 0.0959 0.1289
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0094 0.0071
Loa Loa (eye worm) hypothetical protein 0.0055 0.054 0.0799
Brugia malayi hypothetical protein 0.002 0.0094 0.0097
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.011 0.0192
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0101 0.1113 0.1092
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.1023 0.1023
Brugia malayi Cathepsin L-like precursor 0.0016 0.0051 0.0038
Brugia malayi nuclear receptor RXR 0.0047 0.0433 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni sodium-dependent amino acid transporter 0.0015 0.0036 0.0013
Brugia malayi nuclear receptor NHR-88 0.0088 0.0959 0.1289
Brugia malayi excitatory GABA receptor EXP-1A 0.0018 0.0077 0.0074
Loa Loa (eye worm) hypothetical protein 0.0055 0.054 0.0799
Schistosoma mansoni lamin 0.0053 0.0513 0.0491
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0077 0.0074
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0288 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0025 0.0025
Echinococcus multilocularis lamin dm0 0.0053 0.0513 0.0513
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0018 0.0077 0.0077
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0036 0.0013
Schistosoma mansoni organic anion transporter 0.0087 0.0941 0.092
Schistosoma mansoni hypothetical protein 0.0805 1 1
Entamoeba histolytica hypothetical protein 0.0035 0.0288 0.076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.1626 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0088 0.0959 0.0938
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0018 0.0077 0.0074
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0333 0.4983
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0015 0.0036 0.0017
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0077 0.0077
Schistosoma mansoni thyroid hormone receptor 0.0478 0.587 0.5861
Onchocerca volvulus 0.0018 0.0077 0.0135
Schistosoma mansoni retinoic acid receptor RXR 0.0088 0.0959 0.0938
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0319 0.2235
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0088 0.0959 0.0959
Brugia malayi Nuclear hormone receptor-like 1 0.059 0.7285 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0143 0.1653 0.1653
Brugia malayi glutaminase DH11.1 0.0268 0.322 0.4402
Brugia malayi Cation transporter family protein 0.0018 0.0077 0.0074
Onchocerca volvulus 0.0468 0.5743 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0088 0.0959 0.0959
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0113 0.1268 0.1268
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0051 0.0088
Schistosoma mansoni coup transcription factor 0.0088 0.0959 0.0938
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0232 0.0584
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0042 0.037 0.037
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0081 0.0867 0.0867
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0017
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0092 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.2764 0.2764
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0088 0.0959 0.1419
Schistosoma mansoni lozenge 0.0055 0.0537 0.0515
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0009
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0033 0.001
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0038 0.033 0.085
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0088 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Chlamydia trachomatis glutamine binding protein 0.0038 0.033 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0601 0.0579
Loa Loa (eye worm) hypothetical protein 0.016 0.1859 0.2751
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Toxoplasma gondii aldehyde dehydrogenase 0.0119 0.1352 1
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.006 0.0601 0.4353
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0051 0.0038
Echinococcus multilocularis GPCR, family 2 0.0016 0.0041 0.0041
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0077 0.0114
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0081 0.0867 0.0867
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0513 0.0675
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.1352 0.4057
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0131 0.0131
Giardia lamblia PcnA 0.0063 0.0645 0.1666
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.037 0.037
Echinococcus multilocularis lamin 0.0053 0.0513 0.0513
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Brugia malayi nuclear receptor NHR-67 0.0042 0.037 0.0477
Schistosoma mansoni hypothetical protein 0.0051 0.0489 0.0467
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0301 0.0524
Mycobacterium tuberculosis Conserved protein 0.0035 0.0288 0.0992
Brugia malayi Pre-SET motif family protein 0.006 0.0601 0.0795
Entamoeba histolytica hypothetical protein 0.002 0.0094 0.02
Schistosoma mansoni nuclear receptor 0.0042 0.037 0.0347
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.1609 0.4465
Onchocerca volvulus 0.0053 0.0513 0.0894
Echinococcus multilocularis expressed protein 0.0038 0.0319 0.0319
Trypanosoma cruzi MFS transporter, putative 0.0055 0.054 0.1511
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0023 0.0131 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni nuclear hormone receptor 0.0088 0.0959 0.0938
Loa Loa (eye worm) hypothetical protein 0.006 0.0601 0.0889
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.011 0.012
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0004 0.0011
Leishmania major DNA polymerase kappa, putative 0.0021 0.0107 0.0299
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.054 0.3896
Onchocerca volvulus 0.0087 0.0941 0.1639
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0332 0.0885
Trichomonas vaginalis set domain proteins, putative 0.0467 0.5741 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0088 0.0959 0.1289
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0098 0.0102
Echinococcus granulosus bloom syndrome protein 0.0021 0.011 0.011
Brugia malayi hypothetical protein 0.0042 0.037 0.0477
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0563 0.1576
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Loa Loa (eye worm) RGS-3 protein 0.002 0.0094 0.0139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0433 0.0411
Loa Loa (eye worm) histone methyltransferase 0.002 0.0092 0.0136
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.1023 0.1376
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0009
Schistosoma mansoni ATP-binding cassette transporter 0.0015 0.0033 0.001
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0333 0.0493
Echinococcus granulosus glutamate receptor subunit protein glur 0.0015 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Loa Loa (eye worm) beta-lactamase 0.0035 0.0288 0.0427
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.011 0.0192
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0017
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0288 0.0266
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0288 0.0744
Echinococcus granulosus nuclear receptor nhr 48 0.0042 0.037 0.037
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0034 0.0269 0.0398
Schistosoma mansoni hypothetical protein 0.0081 0.0867 0.0845
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0113 0.1268 0.1268
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0076 0.0213
Schistosoma mansoni lamin 0.0053 0.0513 0.0491
Schistosoma mansoni sodium/chloride dependent transporter 0.0016 0.004 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.044 0.0573
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0098 0.0074
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0513 0.076
Echinococcus granulosus proliferating cell nuclear antigen 0.0063 0.0645 0.0645
Schistosoma mansoni nuclear receptor nhr-48 0.0042 0.037 0.0347
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0368 0.1031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0088 0.0959 0.1289
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0131 0.0131
Onchocerca volvulus 0.0035 0.0288 0.0502
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0288 0.0992
Loa Loa (eye worm) hypothetical protein 0.0053 0.0513 0.076
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0076 0.5
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0098 0.0098
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0088 0.0959 0.0938
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0203 0.0247
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0023 0.0023
Leishmania major cathepsin L-like protease 0.0016 0.0051 0.0142
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0288 0.1775
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0051 0.0051
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0101 0.1113 0.1113
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0051 0.0142
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0077 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0105 0.1172 0.1735
Schistosoma mansoni DNA polymerase eta 0.0014 0.0025 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0427 0.0745
Loa Loa (eye worm) glutaminase 2 0.0268 0.322 0.4763
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0288 0.0503
Echinococcus granulosus ecdysone induced protein 78C 0.0088 0.0959 0.0959
Loa Loa (eye worm) hypothetical protein 0.0039 0.0333 0.0493
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.006 0.0601 0.0579
Leishmania major cathepsin L-like protease 0.0016 0.0051 0.0142
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0203 0.03
Schistosoma mansoni hypothetical protein 0.0333 0.4051 0.4037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0088 0.0959 0.0959
Loa Loa (eye worm) RecQ helicase 0.0021 0.011 0.0163
Onchocerca volvulus 0.0016 0.0051 0.0088
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0088 0.0959 0.0959
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0088 0.0959 0.0938
Onchocerca volvulus Protein ultraspiracle homolog 0.0088 0.0959 0.167
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0301 0.0382
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0051 0.0088
Brugia malayi hypothetical protein 0.0231 0.2764 0.3774
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0015 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Onchocerca volvulus 0.0057 0.0557 0.097
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0288 0.0288
Entamoeba histolytica hypothetical protein 0.0035 0.0288 0.076
Echinococcus multilocularis Protein lozenge 0.0055 0.0537 0.0537
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0018 0.0077 0.0054
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0077 0.0074
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0094 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Toxoplasma gondii proliferating cell nuclear antigen PCNA1 0.0063 0.0645 0.4687
Onchocerca volvulus 0.0015 0.0036 0.0063
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0113 0.1268 0.3792
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0036 0.0036
Brugia malayi nuclear receptor NHR-88 0.0042 0.037 0.0477
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.0033 0.001
Schistosoma mansoni regulator of G protein signaling 0.002 0.0094 0.0071
Echinococcus granulosus histone lysine methyltransferase setb 0.006 0.0601 0.0601
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Schistosoma mansoni survival motor neuron protein 0.0047 0.044 0.0417
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0113 0.1268 0.3549
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0466 0.061
Schistosoma mansoni steroid hormone receptor ad4bp 0.0088 0.0959 0.0938
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.0077 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0088 0.0959 0.1289
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0077 0.0077
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0077 0.0077
Brugia malayi PXA domain containing protein 0.002 0.0094 0.0097
Onchocerca volvulus 0.0053 0.0513 0.0894
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0076 0.0113
Schistosoma mansoni nuclear hormone receptor 0.0042 0.037 0.0347
Loa Loa (eye worm) hypothetical protein 0.0035 0.0288 0.0427
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0368 0.1031
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0232 0.0584
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Echinococcus multilocularis cysteine protease 0.0016 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0139
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0356 0.0935
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Brugia malayi follicle stimulating hormone receptor 0.0234 0.2794 0.3815
Brugia malayi hypothetical protein 0.0035 0.0288 0.0365
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0319 0.0407
Echinococcus multilocularis nAChR subunit 0.0018 0.0077 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0015 0.0036 0.0036
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0088 0.0959 0.1289
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0094 0.0139
Entamoeba histolytica hypothetical protein 0.0035 0.0288 0.076
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0036
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0038 0.033 0.0806
Brugia malayi Pre-SET motif family protein 0.0411 0.5027 0.689
Schistosoma mansoni nuclear receptor 0.0042 0.037 0.0347
Schistosoma mansoni apoptosis regulator bax 0.0081 0.0867 0.0845
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0632 0.1768
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0088 0.0959 0.0938
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.006 0.0601 0.0601
Echinococcus multilocularis thyroid hormone receptor alpha 0.0478 0.587 0.587
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0094 0.0094
Loa Loa (eye worm) runx1 0.0055 0.0537 0.0795
Schistosoma mansoni rab6-interacting 0.0039 0.0333 0.0311
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0051 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.3574 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0501 0.0742
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0094 0.0094
Schistosoma mansoni lipoxygenase 0.0039 0.0333 0.0311
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0036 0.0013
Schistosoma mansoni intermediate filament proteins 0.0053 0.0513 0.0491
Onchocerca volvulus 0.0038 0.0319 0.0556
Onchocerca volvulus Putative organic anion transporter 0.0055 0.054 0.094
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0301 0.0524
Toxoplasma gondii exonuclease III APE 0.0018 0.0076 0.0408
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0332 0.4852
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0051 0.0241
Brugia malayi hypothetical protein 0.016 0.1859 0.2528
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0094 0.0094
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0048 0.0048
Echinococcus granulosus Nuclear hormone receptor HR96 0.0042 0.037 0.037
Brugia malayi hypothetical protein 0.0438 0.5372 0.7365
Loa Loa (eye worm) glutamate receptor 1 0.0015 0.0033 0.0049
Entamoeba histolytica hypothetical protein 0.002 0.0094 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0107 0.0232
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0089 0.009
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0077 0.0074
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.1023 0.1781
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0288 0.0503
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Brugia malayi hypothetical protein 0.0055 0.054 0.0711
Brugia malayi Cathepsin L-like precursor 0.0016 0.0051 0.0038
Echinococcus granulosus agrin 0.0038 0.0319 0.0319
Schistosoma mansoni loxhd1 0.0039 0.0333 0.0311
Echinococcus multilocularis neuropeptide receptor A26 0.0461 0.5665 0.5665
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0018 0.0077 0.0114
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0088 0.0959 0.0959
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0274 0.0703
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0018 0.0077 0.0077
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0051 0.0051
Trypanosoma cruzi proliferative cell nuclear antigen (PCNA), putative 0.0063 0.0645 0.1805
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0077 0.0074
Loa Loa (eye worm) nuclear receptor NHR-67 0.0042 0.037 0.0547
Trypanosoma brucei proliferative cell nuclear antigen (PCNA), putative 0.0063 0.0645 0.1748
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Schistosoma mansoni glutamate receptor AMPA 0.0015 0.0033 0.001
Toxoplasma gondii proliferating cell nuclear antigen PCNA2 0.0034 0.0272 0.1884
Echinococcus granulosus intermediate filament protein 0.0053 0.0513 0.0513
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0376 0.0655
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0004 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0155 0.0229
Brugia malayi Protein kinase domain containing protein 0.0015 0.0027 0.0005
Schistosoma mansoni hypothetical protein 0.0039 0.0333 0.0311
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0356 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.006 0.0601 0.0579
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0023 0.0041
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Brugia malayi CXXC zinc finger family protein 0.0057 0.0557 0.0735
Echinococcus granulosus geminin 0.0333 0.4051 0.4051
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Trichomonas vaginalis proliferating cell nuclear antigen, putative 0.0063 0.0645 0.1124
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0101 0.1113 0.1113
Onchocerca volvulus 0.0016 0.0051 0.0088
Echinococcus granulosus expressed protein 0.0386 0.471 0.471
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0018 0.0077 0.0077
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0015 0.0033 0.0033
Schistosoma mansoni kinase 0.0047 0.0443 0.0421
Schistosoma mansoni regulator of G protein signaling 0.002 0.0094 0.0071
Mycobacterium ulcerans beta-lactamase 0.0035 0.0288 0.0676
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.1023 0.1513
Schistosoma mansoni cpg binding protein 0.0057 0.0557 0.0535
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0051 0.0051
Brugia malayi nuclear hormone receptor 0.0042 0.037 0.0477
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Brugia malayi hypoxia-induced factor 1 0.0147 0.1703 0.2313
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.1023 0.1023
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0333 0.0333
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0356 0.0892
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0301 0.0278
Brugia malayi polk-prov protein 0.0031 0.0232 0.0287
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0023 0.0131 0.0131
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0077 0.0074
Brugia malayi hypothetical protein 0.0055 0.054 0.0711
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0107
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0332 0.0748
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0098 0.0144
Echinococcus multilocularis expressed protein 0.0386 0.471 0.471
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0042 0.037 0.037
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0023 0.0023
Giardia lamblia DINP protein human, muc B family 0.0021 0.0107 0.009
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0098 0.0074
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0018 0.0077 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0051 0.0074
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0088 0.0959 0.1419
Onchocerca volvulus 0.0039 0.0333 0.0581
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0077 0.0074
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0088 0.0959 0.0959
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0319 0.0407
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0632 0.1768
Leishmania major cathepsin L-like protease 0.0016 0.0051 0.0142
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.3574 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0042 0.037 0.0477
Leishmania major cathepsin L-like protease 0.0062 0.0632 0.1768
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0077 0.0077
Schistosoma mansoni follistatin 0.0038 0.0319 0.0296
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0109 0.1215 0.1215
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0466 0.069
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0319 0.2235
Loa Loa (eye worm) hypothetical protein 0.0438 0.5372 0.7948
Brugia malayi beta-lactamase 0.0035 0.0288 0.0365
Echinococcus granulosus Nuclear hormone receptor HR96 0.0042 0.037 0.037
Brugia malayi SPARC precursor 0.0038 0.0319 0.0407
Echinococcus granulosus follistatin 0.0038 0.0319 0.0319
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0025 0.0002
Toxoplasma gondii hypothetical protein 0.0048 0.0445 0.3186
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0023 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0163
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0094 0.0071
Brugia malayi steroid hormone receptor 0.0088 0.0959 0.1289
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0301 0.0796
Mycobacterium ulcerans lipase LipD 0.0035 0.0288 0.0676
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0088 0.0959 0.0959
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0047 0.0433 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0163
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0288 0.0992
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Entamoeba histolytica cysteine protease, putative 0.0016 0.0051 0.0075
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0288 0.0992
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0078 0.0687
Schistosoma mansoni glutaminase 0.0268 0.322 0.3204
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0077 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0368 0.1031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0077 0.0054
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0094 0.0094
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0548 0.6759 1
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.2764 0.2764
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0042 0.037 0.037
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0301 0.0278
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.1352 0.4057
Echinococcus granulosus dna polymerase eta 0.0014 0.0025 0.0025
Loa Loa (eye worm) glutamate receptor 2 0.0015 0.0033 0.0049
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0094 0.0094
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0333 0.0333
Onchocerca volvulus 0.0047 0.044 0.0765
Onchocerca volvulus 0.0088 0.0959 0.167
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0088 0.0959 0.1289
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1023 0.2862
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0301 0.0657
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0231 0.2764 0.4089
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0376 0.5666
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0076 0.0149
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0333 0.0333
Onchocerca volvulus 0.0035 0.0288 0.0502
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0088 0.0959 0.1419
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Echinococcus granulosus glutamate receptor 2 0.0023 0.0131 0.0131
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0319 0.0472
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0513 0.076
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0042 0.037 0.0347
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0076 0.0194
Brugia malayi nuclear hormone receptor family member odr-7 0.0042 0.037 0.0477
Loa Loa (eye worm) hypothetical protein 0.0047 0.0433 0.0641
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.3574 1
Echinococcus multilocularis nmda type glutamate receptor 0.0054 0.0519 0.0519
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0483 0.1352
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0163
Echinococcus granulosus death domain containing protein 0.0014 0.0023 0.0023
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.1352 0.1331
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0076 0.084
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0034
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0094 0.0094
Onchocerca volvulus 0.0016 0.0051 0.0088
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0632 0.1768
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0368 0.0969
Loa Loa (eye worm) hypothetical protein 0.0035 0.0288 0.0427
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0288 0.0992
Loa Loa (eye worm) hypothetical protein 0.0047 0.0433 0.0641
Echinococcus multilocularis sodium and chloride dependent glycine 0.0015 0.0036 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0478 0.587 0.5861
Mycobacterium leprae Probable lipase LipE 0.0035 0.0288 0.1775
Loa Loa (eye worm) norepinephrine transporter 0.0015 0.0036 0.0053
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0094 0.0097
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0036 0.0194
Echinococcus granulosus neuropeptide s receptor 0.0461 0.5665 0.5665
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0288 0.0427
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0048 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Onchocerca volvulus 0.0016 0.0051 0.0088
Echinococcus multilocularis cysteine protease 0.0016 0.0051 0.0051
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0131 0.0131
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.1703 0.252
Leishmania major DNA polymerase eta, putative 0.0014 0.0025 0.0069
Brugia malayi Cytochrome P450 family protein 0.0029 0.0215 0.0263
Schistosoma mansoni nuclear hormone receptor 0.0042 0.037 0.0347
Echinococcus granulosus serotonin transporter 0.0015 0.0036 0.0036
Brugia malayi ecdysone receptor 0.0042 0.037 0.0477
Mycobacterium ulcerans hypothetical protein 0.0156 0.1808 0.5511
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0053
Schistosoma mansoni polycystin 1-related 0.0039 0.0333 0.0311
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0017
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0018 0.0077 0.0074
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0356 0.0621
Brugia malayi Cation transporter family protein 0.0018 0.0077 0.0074
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0041 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0163
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0094 0.0094
Trypanosoma brucei polo-like protein kinase 0.0093 0.1023 0.2813
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0036 0.0036
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0077 0.0114
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0301 0.0524
Trichomonas vaginalis glutaminase, putative 0.0268 0.322 0.5608
Schistosoma mansoni regulator of G protein signaling 0.002 0.0094 0.0071
Trichomonas vaginalis helicase, putative 0.0013 0.0005 0.0009
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Echinococcus granulosus RUN 0.0039 0.0333 0.0333
Brugia malayi conserved hypotetical protein 0.0042 0.037 0.0477
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0288 0.0807
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0319 0.2235
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0048 0.0048
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0087 0.0941 0.0941
Mycobacterium ulcerans aldehyde dehydrogenase 0.0119 0.1352 0.4057
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0098 0.0074
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.1808 0.6706
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0376 0.2662
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Onchocerca volvulus 0.0018 0.0077 0.0135
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0094 0.0071
Loa Loa (eye worm) hypothetical protein 0.0047 0.0433 0.0641
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0051 0.0142
Echinococcus granulosus neuropeptide receptor A26 0.0461 0.5665 0.5665
Plasmodium vivax vivapain-2 0.0016 0.0051 0.043
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0018 0.0077 0.0054
Echinococcus granulosus GPCR family 2 0.0016 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0035 0.0288 0.0427
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0376 0.0655
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0034 0.0272 0.4
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0077 0.0077
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0054 0.0031
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0018 0.0077 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0163
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0076 0.0659
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0288 0.0992
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Loa Loa (eye worm) hypothetical protein 0.0438 0.5372 0.7948
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0094 0.0163
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0376 0.0376
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0632 0.1768
Schistosoma mansoni cpg binding protein 0.006 0.0598 0.0576
Loa Loa (eye worm) hypothetical protein 0.0016 0.0051 0.0075
Plasmodium falciparum proliferating cell nuclear antigen 1 0.0063 0.0645 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.1023 0.2862
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Loa Loa (eye worm) hypothetical protein 0.0101 0.1113 0.1646
Plasmodium falciparum proliferating cell nuclear antigen 2 0.0034 0.0272 0.3882
Brugia malayi Nuclear hormone receptor E75 0.0042 0.037 0.0477
Loa Loa (eye worm) LGC-31 protein 0.0018 0.0077 0.0114
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0018 0.0077 0.0077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0356 0.0997
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0038 0.033 0.1147
Schistosoma mansoni hypothetical protein 0.0333 0.4051 0.4037
Echinococcus multilocularis bloom syndrome protein 0.0021 0.011 0.011
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0077 0.0077
Echinococcus multilocularis proliferating cell nuclear antigen 0.0063 0.0645 0.0645
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0077 0.0054
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.054 0.054
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1023 0.2862
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0463 0.1296
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0139
Onchocerca volvulus 0.0438 0.5372 0.9355
Loa Loa (eye worm) hypothetical protein 0.0038 0.0319 0.0472
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0077 0.0077
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0018 0.0077 0.0114
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0076 0.0213
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0037
Brugia malayi hypothetical protein 0.002 0.0094 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0076 0.0073
Brugia malayi hypothetical protein 0.0039 0.0333 0.0427
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0094 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0083
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0051 0.0027
Toxoplasma gondii hypothetical protein 0.0015 0.0036 0.0107
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0119 0.1352 0.4989
Brugia malayi Glutamate receptor 2 precursor 0.0015 0.0033 0.0014
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.006 0.0601 0.0601
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.1384 0.1364
Leishmania major hypothetical protein, conserved 0.0035 0.0288 0.0807
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Leishmania major protein kinase, putative 0.0013 0.0004 0.0011
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0036 0.0013
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0018 0.0077 0.0114
Schistosoma mansoni agrin 0.0038 0.0319 0.0296
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.8366 0.8362
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0466 0.061
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Schistosoma mansoni glutamate receptor NMDA 0.0023 0.0131 0.0107
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0113 0.1268 0.1714
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0113 0.1268 0.1248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Brugia malayi hypothetical protein 0.0042 0.037 0.0477
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0094 0.0139
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0017
Onchocerca volvulus 0.0042 0.037 0.0644
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1023 0.1782
Loa Loa (eye worm) hypothetical protein 0.0025 0.0155 0.0229
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0356 0.0621
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0288 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Onchocerca volvulus 0.0015 0.0036 0.0063
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.2685 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0033 0.001
Loa Loa (eye worm) hypothetical protein 0.0038 0.0319 0.0472
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.1266 0.936
Loa Loa (eye worm) hypothetical protein 0.0055 0.054 0.0799
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0763 0.0763
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0018 0.0077 0.0054
Loa Loa (eye worm) DR-78 0.0042 0.037 0.0547
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0301 0.0841
Onchocerca volvulus Bile acid receptor homolog 0.0088 0.0959 0.167
Schistosoma mansoni aldehyde dehydrogenase 0.0119 0.1352 0.1331
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0356 0.0997
Brugia malayi Nuclear hormone receptor-like 1 0.0548 0.6759 0.9276
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0088 0.0959 0.1289
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0088 0.0959 0.0959
Schistosoma mansoni regulator of G protein signaling 0.002 0.0094 0.0071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0113 0.1268 0.3792
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0319 0.2235
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0356 0.0892
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0119 0.1352 0.1352
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0051 0.0088
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0042 0.037 0.0547
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0015 0.0033 0.0033
Brugia malayi Cathepsin L-like precursor 0.0016 0.0051 0.0038
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0081 0.0867 0.0845
Schistosoma mansoni hypothetical protein 0.0389 0.4755 0.4743
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0094 0.0094
Loa Loa (eye worm) fibroinase 0.0016 0.0051 0.0075
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0077 0.0077
Echinococcus granulosus sodium and chloride dependent glycine 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Plasmodium vivax SET domain protein, putative 0.006 0.0601 0.9286
Onchocerca volvulus 0.0087 0.0941 0.1639
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0017
Mycobacterium ulcerans hypothetical protein 0.0035 0.0288 0.0676
Loa Loa (eye worm) apoptosis regulator protein 0.0081 0.0867 0.1282
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0015 0.0036 0.1091
Schistosoma mansoni RAR-like nuclear receptor 0.0088 0.0959 0.0938
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0119 0.1352 0.3782
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0445 0.0422
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.1626 0.602
Entamoeba histolytica proliferating cell nuclear antigen, putative 0.0063 0.0645 0.179
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0041 0.0041
Brugia malayi PXA domain containing protein 0.002 0.0094 0.0097
Loa Loa (eye worm) hypothetical protein 0.0055 0.054 0.0799
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0051 0.0075
Loa Loa (eye worm) solute carrier family 6 member 4 0.0015 0.0036 0.0053
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0288 0.0992
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0018 0.0077 0.0114
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0041 0.0024
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0004 0.0011
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0023 0.000000041547
Brugia malayi Glutamate receptor 1 precursor 0.0015 0.0033 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0088 0.0959 0.1289
Echinococcus granulosus dna polymerase kappa 0.0041 0.0356 0.0356
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0077 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0009
Echinococcus granulosus cpg binding protein 0.006 0.0598 0.0598
Echinococcus multilocularis nuclear receptor nhr 48 0.0042 0.037 0.037
Plasmodium vivax proliferating cell nuclear antigen, putative 0.0063 0.0645 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0215 0.0317
Schistosoma mansoni proliferating cell nuclear antigen 0.0063 0.0645 0.0623
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0076 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0288 0.0288
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0427 0.0745
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0048 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0411 0.5027 0.7437
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0088 0.0959 0.167
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0139
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0081 0.0867 0.0867
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0051 0.0075
Brugia malayi beta-lactamase family protein 0.0035 0.0288 0.0365
Brugia malayi Steroid receptor seven-up type 2 0.0088 0.0959 0.1289
Schistosoma mansoni axis inhibition protein axin 0.002 0.0094 0.0071
Leishmania major protein kinase, putative 0.0013 0.0004 0.0011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0047 0.0433 0.0411
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0077 0.0077
Onchocerca volvulus 0.0018 0.0077 0.0135
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Entamoeba histolytica hypothetical protein 0.0035 0.0288 0.076
Onchocerca volvulus 0.0055 0.054 0.094
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.0081 0.0867 0.1282
Schistosoma mansoni zinc finger protein 0.0042 0.037 0.0347
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0048 0.0025
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.3492 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0107 0.031
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.8366 0.8366
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0269 0.0339
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0038 0.033 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Schistosoma mansoni cpg binding protein 0.006 0.0598 0.0576
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0076 0.0213
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0288 0.0365
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0023 0.0023
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0167 0.0167
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0558 0.0558
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0288 0.0676
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0139
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0094 0.0097
Mycobacterium ulcerans glutaminase 0.0268 0.322 1
Brugia malayi Nuclear hormone receptor E75 0.0042 0.037 0.0477
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0041 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.1626 0.493
Leishmania major proliferative cell nuclear antigen (PCNA), putative 0.0063 0.0645 0.1805
Onchocerca volvulus 0.0018 0.0077 0.0135
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Brugia malayi Cathepsin L-like precursor 0.0016 0.0051 0.0038
Brugia malayi Death domain containing protein 0.0014 0.0023 0.000000057079
Onchocerca volvulus 0.0015 0.0036 0.0063
Onchocerca volvulus 0.006 0.0601 0.1046
Schistosoma mansoni hypothetical protein 0.0016 0.0041 0.0017
Echinococcus multilocularis RUN 0.0039 0.0333 0.0333
Echinococcus granulosus lamin dm0 0.0053 0.0513 0.0513
Brugia malayi Nuclear hormone receptor-like 1 0.0548 0.6759 0.9276
Brugia malayi beta-lactamase family protein 0.0035 0.0288 0.0365
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0094 0.0071
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0088 0.0959 0.0938
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0036 0.0013
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0042 0.037 0.0644
Brugia malayi intermediate filament protein 0.0053 0.0513 0.0675
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Brugia malayi nuclear hormone receptor 0.0088 0.0959 0.1289
Schistosoma mansoni lipoxygenase 0.0109 0.1215 0.1194
Toxoplasma gondii hypothetical protein 0.0015 0.0036 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0004 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0015 0.0036 0.0013
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0025 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Brugia malayi Uncoordinated protein 44 0.0014 0.0023 0.000000057079
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0051 0.0088
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0015 0.0036 0.0036
Echinococcus multilocularis Ankyrin 0.0014 0.0025 0.0025
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0301 0.0301
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0036 0.0013
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0333 0.0333
Brugia malayi nuclear hormone receptor family member nhr-6 0.0042 0.037 0.0477
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0051 0.0074
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0076 0.0076
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0288 0.0288
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0763 0.0763
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.2794 0.4133
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0041 0.0024
Leishmania major cathepsin L-like protease 0.0016 0.0051 0.0142
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.001
Echinococcus multilocularis serotonin transporter 0.0015 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0036 0.0013
Loa Loa (eye worm) hypothetical protein 0.0087 0.0941 0.1393
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0038 0.033 0.085
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Onchocerca volvulus 0.0055 0.054 0.094
Loa Loa (eye worm) proliferating cell nuclear antigen 0.0063 0.0645 0.0954
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0018 0.0077 0.0077
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0051 0.0027
Schistosoma mansoni proliferating cell nuclear antigen 0.0063 0.0645 0.0623
Brugia malayi hypothetical protein 0.0047 0.0433 0.0564
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Plasmodium vivax vivapain-2 0.0016 0.0051 0.043
Loa Loa (eye worm) hypothetical protein 0.0049 0.0466 0.069
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0005 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0088 0.0959 0.1289
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0042 0.037 0.0644
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0025 0.0002
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0015 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0026 0.0167 0.0247
Loa Loa (eye worm) hypothetical protein 0.0035 0.0288 0.0427
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0319 0.0407
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0101 0.1113 0.1092
Onchocerca volvulus Putative organic anion transporter 0.0055 0.054 0.094
Onchocerca volvulus 0.0035 0.0288 0.0502
Schistosoma mansoni ap endonuclease 0.0018 0.0076 0.0053
Loa Loa (eye worm) hypothetical protein 0.0039 0.0333 0.0493
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0139
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0025 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0088 0.0959 0.1419
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0025 0.0001
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Brugia malayi Doublecortin family protein 0.0039 0.0333 0.0427
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.0959 0.0959
Echinococcus granulosus glutamate NMDA receptor subunit 0.0015 0.0033 0.0033
Leishmania major cathepsin L-like protease 0.0062 0.0632 0.1768
Loa Loa (eye worm) hypothetical protein 0.0055 0.054 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0094 0.0163
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0076 0.0076
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0015 0.0033 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0288 0.0807
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0301 0.0841
Onchocerca volvulus 0.0039 0.0333 0.0581
Trypanosoma brucei unspecified product 0.0034 0.0274 0.0703
Brugia malayi hypothetical protein 0.0039 0.0333 0.0427
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Echinococcus multilocularis FTZ F1 alpha 0.0088 0.0959 0.0959
Echinococcus granulosus Ankyrin 0.0014 0.0025 0.0025
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0319 0.0472
Toxoplasma gondii ABC1 family protein 0.0035 0.0288 0.2006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Schistosoma mansoni hypothetical protein 0.0081 0.0867 0.0845
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0018 0.0077 0.0074
Brugia malayi Cathepsin L-like precursor 0.0016 0.0051 0.0038
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0101 0.1113 0.1092
Brugia malayi ecdysteroid receptor 0.0088 0.0959 0.1289
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0333 0.0333
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0015 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0094 0.0139
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0107 0.0299
Trichomonas vaginalis esterase, putative 0.0035 0.0288 0.0503
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0077 0.0077
Leishmania major cathepsin L-like protease 0.0062 0.0632 0.1768
Brugia malayi orphan nuclear receptor NR2E1 0.0042 0.037 0.0477
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0131 0.0131
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0389 0.4755 0.4755
Onchocerca volvulus 0.0016 0.0051 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0088 0.0959 0.1289
Onchocerca volvulus 0.0018 0.0077 0.0135
Brugia malayi sodium-independent organic anion transporter family protein 0.0087 0.0941 0.1264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Echinococcus granulosus lamin 0.0053 0.0513 0.0513
Brugia malayi prostaglandin transporter 0.0055 0.054 0.0711
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0113 0.1268 0.4676
Loa Loa (eye worm) hypothetical protein 0.0101 0.1113 0.1646
Echinococcus multilocularis musashi 0.0053 0.0513 0.0513
Echinococcus granulosus nAChR subunit 0.0018 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0077 0.0114
Loa Loa (eye worm) cysteine protease 0.0016 0.0051 0.0075
Loa Loa (eye worm) hypothetical protein 0.0016 0.0041 0.006
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0088 0.0959 0.1289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0005 0.0009
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.1602 0.1602
Schistosoma mansoni single-minded 0.0048 0.0445 0.0422
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0047 0.0433 0.0433
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.3574 1
Onchocerca volvulus Putative organic anion transporter 0.0055 0.054 0.094
Giardia lamblia Kinase, PLK 0.0093 0.1023 0.2772
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0088 0.0959 0.0959
Loa Loa (eye worm) steroid hormone receptor 0.0088 0.0959 0.1419
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0088 0.0959 0.0959
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0018 0.0077 0.0074
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0015 0.0036 0.0036
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0094 0.0094
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0025 0.0036
Echinococcus granulosus microtubule associated protein 2 0.0675 0.8366 0.8366
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0376 0.2662
Mycobacterium tuberculosis Conserved protein 0.0035 0.0288 0.0992
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0076 0.0145
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.3492 0.6082
Schistosoma mansoni nAChR subunit 0.0018 0.0077 0.0054
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0301 0.0301
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0051 0.0088
Echinococcus granulosus axis inhibition protein axin 0.002 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0015 0.0036 0.0053
Echinococcus multilocularis dna polymerase eta 0.0014 0.0025 0.0025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0088 0.0959 0.1289
Echinococcus multilocularis agrin 0.0038 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0088 0.0959 0.1419
Schistosoma mansoni rab6-interacting 0.0039 0.0333 0.0311
Entamoeba histolytica hypothetical protein 0.002 0.0094 0.02
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0042 0.037 0.0347
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0094 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0088 0.0959 0.1289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.3492 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0356 0.0935
Toxoplasma gondii cathepsin CPL 0.0016 0.0051 0.0217
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0042 0.037 0.037
Onchocerca volvulus 0.0016 0.0051 0.0088
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0092 0.0092
Echinococcus multilocularis follistatin 0.0038 0.0319 0.0319
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0051 0.0051
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0015 0.0036 0.0013
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0301 0.0841
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0288 0.0503
Loa Loa (eye worm) glutaminase 0.0268 0.322 0.4763
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0088 0.0959 0.1419
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0167 0.0167
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0077 0.0054
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0005 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088
Brugia malayi tailless protein 0.0042 0.037 0.0477
Onchocerca volvulus Putative nachr subunit 0.0018 0.0077 0.0135
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0632 0.1711
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0288 0.0365
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0015 0.0036 0.0107
Echinococcus granulosus thyroid hormone receptor alpha 0.0042 0.037 0.037
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0051 0.0051
Echinococcus multilocularis cpg binding protein 0.006 0.0598 0.0598
Schistosoma mansoni glutamate receptor kainate 0.0015 0.0033 0.001
Echinococcus granulosus FTZ F1 alpha 0.0088 0.0959 0.0959
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0301 0.0301
Schistosoma mansoni hypothetical protein 0.0047 0.044 0.0417
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0034 0.0269 0.0246
Loa Loa (eye worm) hypothetical protein 0.0042 0.037 0.0547
Loa Loa (eye worm) hypothetical protein 0.0038 0.0319 0.0472
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0094 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0051 0.0088

Activities

Activity type Activity value Assay description Source Reference
Decrease (functional) = 16 % Maximum percentage decrease in immobility time was determined by despair test at a dose of 0.3 mg/kg in Male albino Swiss mice ChEMBL. 11300875

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.