Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0078 | 0.0717 | 0.0961 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | amine GPCR | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | Carboxylesterase family protein | 0.0464 | 0.6738 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Echinococcus multilocularis | g protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | g protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | adenoreceptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | neuroligin | 0.0078 | 0.0717 | 0.0961 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | g-protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | neuropeptide receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | Carboxylesterase family protein | 0.0078 | 0.0717 | 0.0961 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0172 | 0.2171 | 0.2067 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | carboxylesterase | 0.0078 | 0.0717 | 0.0719 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0078 | 0.0717 | 0.0594 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0172 | 0.2171 | 1 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0078 | 0.0717 | 0.5 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | Dopamine receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.9974 | 1 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | biogenic amine receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | Carboxylesterase family protein | 0.0078 | 0.0717 | 0.0961 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | Serotonin receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0078 | 0.0717 | 0.0961 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | Melatonin receptor type 1A | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | serotonin receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.6738 | 0.6756 |
Echinococcus granulosus | acetylcholinesterase | 0.0464 | 0.6738 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | neuropeptide s receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0078 | 0.0717 | 0.0594 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | G protein-coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.6738 | 0.6756 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.2171 | 0.2067 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus granulosus | neuropeptide Y receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | neuroligin | 0.0078 | 0.0717 | 0.0961 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | orexin receptor type 2 | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | myosin xvIII | 0.0172 | 0.2171 | 0.2067 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0172 | 0.2171 | 0.3143 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | serotonin receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0464 | 0.6738 | 0.6756 |
Echinococcus granulosus | neuropeptide receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0464 | 0.6738 | 0.6695 |
Loa Loa (eye worm) | carboxylesterase | 0.0078 | 0.0717 | 0.0719 |
Echinococcus granulosus | acetylcholinesterase | 0.0464 | 0.6738 | 1 |
Schistosoma mansoni | gliotactin | 0.0078 | 0.0717 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | fmrfamide receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | sex peptide receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | Carboxylesterase family protein | 0.0464 | 0.6738 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0464 | 0.6738 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0037 | 0.0077 | 0.0077 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0078 | 0.0717 | 0.0961 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | carboxylesterase | 0.0464 | 0.6738 | 0.6756 |
Echinococcus granulosus | serotonin receptor | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | G-protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | putative neuropeptide receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | neuropeptide receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | amine GPCR | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0078 | 0.0717 | 0.0961 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | amine GPCR | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0078 | 0.0717 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0078 | 0.0717 | 0.0594 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Schistosoma mansoni | amine GPCR | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | opsin-like receptor | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | opsin-like receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.9974 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | Dopamine receptor protein 2 | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | G-protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0172 | 0.2171 | 0.3143 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus granulosus | g protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0172 | 0.2171 | 0.3143 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0078 | 0.0717 | 0.5 |
Brugia malayi | GnHR receptor homolog | 0.0172 | 0.2171 | 0.3143 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0078 | 0.0717 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | fmrfamide receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0172 | 0.2171 | 0.2177 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0078 | 0.0717 | 0.0961 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | allatostatin A receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | sulfakinin receptor protein | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | larval opioid receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | histamine h1 receptor | 0.0172 | 0.2171 | 0.2067 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0078 | 0.0717 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0464 | 0.6738 | 1 |
Brugia malayi | Serotonin receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | neuropeptide receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | RE15519p | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0078 | 0.0717 | 0.0961 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | neuropeptide receptor | 0.0172 | 0.2171 | 0.2067 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | Carboxylesterase family protein | 0.0078 | 0.0717 | 0.0961 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0172 | 0.2171 | 0.3143 |
Onchocerca volvulus | 0.0172 | 0.2171 | 1 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | carboxylesterase 5A | 0.0464 | 0.6738 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0464 | 0.6738 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | neuropeptide receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | ORL1-like opioid receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0078 | 0.0717 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0172 | 0.2171 | 0.3143 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0172 | 0.2171 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | biogenic amine receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0172 | 0.2171 | 0.3143 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0078 | 0.0717 | 0.5 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | Carboxylesterase family protein | 0.0078 | 0.0717 | 0.0961 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | allatostatin A receptor | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | neuropeptide F receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | acetylcholinesterase | 0.0078 | 0.0717 | 0.0594 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | opsin-like receptor | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Echinococcus granulosus | g protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0717 | 0.0961 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | Dopamine receptor protein 1 | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0078 | 0.0717 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0717 | 0.0719 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | fmrfamide receptor | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | biogenic amine receptor | 0.0172 | 0.2171 | 0.2067 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | AKH receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Echinococcus multilocularis | neuropeptide receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0172 | 0.2171 | 0.2067 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | hypothetical protein | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0172 | 0.2171 | 0.3143 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.2171 | 0.2067 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0172 | 0.2171 | 0.3143 |
Brugia malayi | follicle stimulating hormone receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus multilocularis | g protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.2171 | 0.2177 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0172 | 0.2171 | 0.2067 |
Brugia malayi | neuropeptide F receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | somatostatin receptor | 0.0172 | 0.2171 | 0.3143 |
Echinococcus granulosus | g protein coupled receptor | 0.0172 | 0.2171 | 0.3143 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 0.25 nM | Binding affinity (Ki) against binding of [3H]-NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M3 | ChEMBL. | 11831911 |
Ki (binding) | = 0.82 nM | Binding affinity (Ki) against binding of [3H]-NMS to membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M2 | ChEMBL. | 11831911 |
Ki (binding) | = 2.3 nM | Binding affinity (Ki) against binding of [3H]-NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M4 | ChEMBL. | 11831911 |
Ki (binding) | = 14 nM | Binding affinity (Ki) against binding of [3H]-NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M1 | ChEMBL. | 11831911 |
Ki (binding) | = 150 nM | Binding affinity (Ki) against binding of [3H]-NMS using membranes from CHO cells expressing cloned human Muscarinic acetylcholine receptor M5 | ChEMBL. | 11831911 |
Selectivity (binding) | = 3.3 | Selectivity ratio of the compound (m2/m3) | ChEMBL. | 11831911 |
Selectivity (binding) | = 9 | Selectivity ratio of the compound (m4/m3) | ChEMBL. | 11831911 |
Selectivity (binding) | = 54 | Selectivity ratio of the compound (m1/m3) | ChEMBL. | 11831911 |
Selectivity (binding) | = 580 | Selectivity ratio of the compound (m5/m3) | ChEMBL. | 11831911 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.