Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0096 | 0.0939 | 0.0992 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.4433 | 0.6302 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0096 | 0.0939 | 0.1318 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0096 | 0.0939 | 0.0992 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0726 | 0.7558 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0396 | 0.4088 | 0.4088 |
Echinococcus multilocularis | cathepsin L | 0.0008 | 0.0015 | 0.0016 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.0041 | 0.0037 |
Brugia malayi | hypothetical protein | 0.0229 | 0.2333 | 0.3307 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0462 | 0.0634 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0096 | 0.0939 | 0.0992 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0229 | 0.2333 | 0.2464 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0096 | 0.0939 | 0.1315 |
Echinococcus multilocularis | Protein lozenge | 0.0054 | 0.0493 | 0.052 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0096 | 0.0939 | 0.0939 |
Brugia malayi | nuclear hormone receptor | 0.0675 | 0.7023 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0008 | 0.0015 | 0.0015 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0098 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0098 | 0.0114 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0098 | 0.0118 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0396 | 0.4088 | 0.4088 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0096 | 0.0939 | 0.0992 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0045 | 0.0405 | 0.0428 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0096 | 0.0939 | 0.1315 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0045 | 0.0405 | 0.0552 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0096 | 0.0939 | 0.0939 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0018 | 0.0018 |
Echinococcus granulosus | FTZ F1 alpha | 0.0096 | 0.0939 | 0.0939 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0316 | 0.0316 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0096 | 0.0939 | 0.1194 |
Brugia malayi | ecdysteroid receptor | 0.0096 | 0.0939 | 0.1318 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0096 | 0.0939 | 0.1318 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0396 | 0.4088 | 0.4319 |
Onchocerca volvulus | 0.0045 | 0.0405 | 0.0483 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0045 | 0.0405 | 0.0405 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0576 | 0.955 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0096 | 0.0939 | 0.1318 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0096 | 0.0939 | 0.1318 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.0599 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0045 | 0.0405 | 0.0405 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0236 | 0.0236 |
Onchocerca volvulus | 0.0429 | 0.4433 | 0.5842 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Brugia malayi | hypothetical protein | 0.0429 | 0.4433 | 0.6303 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0096 | 0.0939 | 0.0939 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0051 | 0.0462 | 0.0488 |
Brugia malayi | nuclear receptor RXR | 0.0045 | 0.0405 | 0.0556 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0098 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0096 | 0.0939 | 0.1318 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.022 | 0.0292 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0096 | 0.0939 | 0.0992 |
Schistosoma mansoni | thyroid hormone receptor | 0.0096 | 0.0939 | 0.0939 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0096 | 0.0939 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0462 | 0.0634 |
Loa Loa (eye worm) | DR-78 | 0.0045 | 0.0405 | 0.0552 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0096 | 0.0939 | 0.1318 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0096 | 0.0939 | 0.0939 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0096 | 0.0939 | 0.0992 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0098 | 0.0114 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.0098 | 0.1415 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0098 | 0.0114 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0096 | 0.0939 | 0.1315 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0096 | 0.0939 | 0.0992 |
Brugia malayi | nuclear receptor NHR-88 | 0.0045 | 0.0405 | 0.0556 |
Onchocerca volvulus | 0.0096 | 0.0939 | 0.1194 | |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0907 | 0.9466 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0045 | 0.0405 | 0.0405 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0051 | 0.0462 | 0.0462 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.0098 | 0.0075 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0096 | 0.0939 | 0.1315 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0045 | 0.0405 | 0.0405 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0045 | 0.0405 | 0.0556 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0096 | 0.0939 | 0.1318 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0034 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0051 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0096 | 0.0939 | 0.1318 |
Onchocerca volvulus | 0.0047 | 0.0418 | 0.0501 | |
Brugia malayi | tailless protein | 0.0045 | 0.0405 | 0.0556 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.0015 | 0.0015 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0045 | 0.0405 | 0.0483 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.0437 | 0.7234 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Schistosoma mansoni | lozenge | 0.0054 | 0.0493 | 0.0493 |
Brugia malayi | steroid hormone receptor | 0.0096 | 0.0939 | 0.1318 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0098 | 0.0103 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.0041 | 0.3182 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0096 | 0.0939 | 0.0939 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0045 | 0.0405 | 0.0428 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0096 | 0.0939 | 0.1318 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0098 | 0.1415 |
Onchocerca volvulus | 0.0045 | 0.0405 | 0.0483 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0576 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0034 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0418 | 0.0418 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0418 | 0.0418 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0045 | 0.0405 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0034 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0096 | 0.0939 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.4433 | 0.6302 |
Brugia malayi | nuclear receptor RXR | 0.0051 | 0.0462 | 0.0637 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0096 | 0.0939 | 0.1318 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0316 | 0.0334 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0045 | 0.0405 | 0.0428 |
Echinococcus granulosus | cathepsin L | 0.0008 | 0.0015 | 0.0015 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus granulosus | cysteine protease | 0.0008 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.0599 | 0.0829 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0599 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0011 | 0.0041 | 0.045 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0576 | 0.955 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0576 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0098 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0096 | 0.0939 | 0.1194 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0229 | 0.2333 | 0.2333 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0224 | 0.2283 | 0.3234 |
Schistosoma mansoni | coup transcription factor | 0.0096 | 0.0939 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.052 | 0.8649 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0051 | 0.0462 | 0.0634 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0045 | 0.0405 | 0.0428 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0096 | 0.0939 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0096 | 0.0939 | 0.0939 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0011 | 0.0041 | 0.0041 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.0041 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0098 | 0.0114 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0045 | 0.0405 | 0.0556 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0405 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0098 | 0.0118 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0051 | 0.0462 | 0.0637 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.0599 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0096 | 0.0939 | 0.1318 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.0098 | 0.1415 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0045 | 0.0405 | 0.0556 |
Brugia malayi | nuclear hormone receptor | 0.0096 | 0.0939 | 0.1318 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0045 | 0.0405 | 0.0405 |
Brugia malayi | follicle stimulating hormone receptor | 0.0224 | 0.2283 | 0.3236 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0096 | 0.0939 | 0.1318 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0096 | 0.0939 | 0.0992 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0045 | 0.0405 | 0.0405 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0098 | 0.0114 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0096 | 0.0939 | 0.0939 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.0015 | 0.0015 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0096 | 0.0939 | 0.1318 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0098 | 0.0098 |
Brugia malayi | nuclear receptor NHR-67 | 0.0045 | 0.0405 | 0.0556 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0045 | 0.0405 | 0.0483 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0098 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.063 | 0.6546 | 0.9319 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0675 | 0.7023 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0462 | 0.0637 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0236 | 0.0236 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0098 | 0.0098 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0064 | 0.0599 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0098 | 0.0098 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.0098 | 1 |
Schistosoma mansoni | nuclear receptor | 0.0045 | 0.0405 | 0.0405 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0098 | 0.0114 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.022 | 0.0288 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0045 | 0.0405 | 0.0405 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.022 | 0.022 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0041 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0462 | 0.0634 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0481 | 1 |
Onchocerca volvulus | 0.0028 | 0.022 | 0.0237 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0418 | 0.0575 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0096 | 0.0939 | 0.0939 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0098 | 0.0098 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0096 | 0.0939 | 0.0939 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0096 | 0.0939 | 0.1315 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0576 | 0.9614 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0018 | 0.0019 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0098 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0462 | 0.0634 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0096 | 0.0939 | 0.1318 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0098 | 0.0103 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0599 | 1 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0576 | 0.955 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0096 | 0.0939 | 0.0939 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0098 | 0.0118 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0045 | 0.0405 | 0.0556 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0098 | 0.0118 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.0041 | 0.0037 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0045 | 0.0405 | 0.0405 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0045 | 0.0405 | 0.0428 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0096 | 0.0939 | 0.0939 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0098 | 0.0103 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0045 | 0.0405 | 0.0552 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0098 | 0.0103 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0096 | 0.0939 | 0.0992 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0045 | 0.0405 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0051 | 0.0462 | 0.0462 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.0599 | 0.0633 |
Schistosoma mansoni | zinc finger protein | 0.0045 | 0.0405 | 0.0405 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0462 | 0.0637 |
Loa Loa (eye worm) | runx1 | 0.0054 | 0.0493 | 0.0678 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0096 | 0.0939 | 0.0939 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.2333 | 0.3304 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0045 | 0.0405 | 0.0405 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.0041 | 0.0037 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0098 | 0.0075 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0098 | 0.0118 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0236 | 0.0236 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0096 | 0.0939 | 0.1318 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.0599 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0096 | 0.0939 | 0.0939 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0096 | 0.0939 | 0.1315 |
Schistosoma mansoni | thyroid hormone receptor | 0.0096 | 0.0939 | 0.0939 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0236 | 0.025 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Onchocerca volvulus | 0.0016 | 0.0098 | 0.0075 | |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.0599 | 0.0833 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0547 | 0.0547 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0098 | 0.0103 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0098 | 0.0075 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0045 | 0.0405 | 0.0405 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0045 | 0.0405 | 0.0556 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0008 | 0.0017 | 0.0002 |
Schistosoma mansoni | nuclear hormone receptor | 0.0045 | 0.0405 | 0.0405 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0576 | 0.9614 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0098 | 0.0103 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.0599 | 0.0599 |
Brugia malayi | ecdysone receptor | 0.0045 | 0.0405 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.0098 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0576 | 0.9614 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0098 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0096 | 0.0939 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0462 | 0.0634 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0405 | 0.0552 |
Schistosoma mansoni | nuclear hormone receptor | 0.0096 | 0.0939 | 0.0939 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0096 | 0.0939 | 0.1318 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0405 | 0.0556 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0051 | 0.0462 | 0.0637 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0958 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0096 | 0.0939 | 0.1318 |
Brugia malayi | conserved hypotetical protein | 0.0045 | 0.0405 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0939 | 0.1315 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
clogP | = 3.17 | Calculated partition coefficient (clogP) (relative to BAY K 8644) | ChEMBL. | 8151623 |
CMR (ADMET) | = 8.01 | CMR value (relative to BAY K 8644) | ChEMBL. | 8151623 |
EC50 (functional) | = 0.0568 | Effective concentration required for force of contraction relative to BAY K 8644 | ChEMBL. | 8151623 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.