Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0021 | 0.0467 | 0.0242 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.1015 | 0.6353 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0029 | 0.1598 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0021 | 0.0467 | 0.292 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0029 | 0.1598 | 1 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0021 | 0.0467 | 0.9876 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.1015 | 0.0803 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0717 | 0.0592 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0021 | 0.0467 | 0.292 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0021 | 0.0467 | 0.0242 |
Toxoplasma gondii | FATC domain-containing protein | 0.0029 | 0.1598 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.4581 | 0.4769 |
Giardia lamblia | GTOR | 0.0021 | 0.0467 | 0.5 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0021 | 0.0467 | 0.0242 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.1598 | 1 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0021 | 0.0467 | 0.292 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0717 | 0.0592 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0473 | 0.2957 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.1214 | 0.151 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0021 | 0.0467 | 0.0581 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0894 | 0.0667 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.161 | 0.1199 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.8037 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0294 | 0.0366 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0894 | 0.1112 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0717 | 0.0891 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0021 | 0.0467 | 0.0192 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.1214 | 0.1287 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0021 | 0.0467 | 0.292 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0021 | 0.0467 | 0.9876 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0021 | 0.0467 | 0.292 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0294 | 0.0366 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.3853 | 0.3552 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0021 | 0.0467 | 0.292 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0069 | 0.7437 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.1214 | 0.1287 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0021 | 0.0467 | 0.292 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0473 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.4261 | 0.4413 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0294 | 0.0366 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.1598 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0069 | 0.7437 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.9283 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.3864 | 0.3972 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0021 | 0.0467 | 0.292 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0021 | 0.0467 | 0.292 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0021 | 0.0467 | 0.0242 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0042 | 0.3456 | 0.4427 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0294 | 0.0366 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0021 | 0.0467 | 0.9876 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0029 | 0.1598 | 0.1826 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0029 | 0.1598 | 0.1989 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0021 | 0.0467 | 0.0192 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0021 | 0.0467 | 0.9876 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0021 | 0.0467 | 0.292 |
Echinococcus granulosus | serine protein kinase ATM | 0.0029 | 0.1598 | 0.1826 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0021 | 0.0467 | 0.9876 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0042 | 0.3456 | 0.4427 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0029 | 0.1598 | 0.1187 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0397 | 0.0114 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0021 | 0.0467 | 0.0581 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.