Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Escherichia coli | 3-dehydroquinate synthase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | 3-dehydroquinate synthase | 0.0258 | 1 | 1 |
Mycobacterium leprae | 3-dehydroquinate synthase AroB | 0.0258 | 1 | 1 |
Mycobacterium tuberculosis | 3-dehydroquinate synthase AroB | 0.0258 | 1 | 1 |
Schistosoma mansoni | 3-dehydroquinate synthase | 0.0258 | 1 | 0.5 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0258 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 0.00000022 M | Compound was evaluated for its inhibitory constant against 3-dehydroquinate synthase | ChEMBL. | 7241506 |
Ki (binding) | = 0.00000022 M | Compound was evaluated for its inhibitory constant against 3-dehydroquinate synthase | ChEMBL. | 7241506 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.