Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Protein kinase domain containing protein | 0.0016 | 0.0128 | 0.0151 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.0005 |
Brugia malayi | Cytochrome P450 family protein | 0.0036 | 0.0356 | 0.0597 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0075 | 0.008 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Ets-domain containing protein | 0.0079 | 0.0842 | 0.1545 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0012 | 0.0075 | 0.0106 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0098 | 0.1051 | 0.3811 |
Trichomonas vaginalis | methylated-DNA--protein-cysteine methyltransferase, putative | 0.0134 | 0.1458 | 0.4971 |
Entamoeba histolytica | hypothetical protein | 0.0098 | 0.1051 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0315 | 0.0997 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0279 | 0.0226 |
Brugia malayi | transcription factor E74 isoform | 0.0012 | 0.0075 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0106 | 0.0144 |
Echinococcus multilocularis | lamin | 0.003 | 0.0279 | 0.0226 |
Brugia malayi | follicle stimulating hormone receptor | 0.0256 | 0.2843 | 0.5451 |
Treponema pallidum | methylated-DNA-protein-cysteine S-methyltransferase (dat) | 0.0134 | 0.1458 | 0.5 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0273 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0124 | 0.0192 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0012 | 0.0075 | 0.0106 |
Brugia malayi | Pre-SET motif family protein | 0.0228 | 0.2525 | 0.483 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0016 | 0.012 | 0.0154 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0016 | 0.012 | 0.0249 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.1703 |
Mycobacterium tuberculosis | Methylated-DNA--protein-cysteine methyltransferase Ogt (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltra | 0.0407 | 0.4545 | 1 |
Onchocerca volvulus | 0.0033 | 0.0315 | 0.0931 | |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0012 | 0.0075 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0712 | 0.1728 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.0062 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0229 | 0.1041 |
Leishmania major | cytochrome p450-like protein | 0.0016 | 0.012 | 0.0249 |
Loa Loa (eye worm) | cytochrome P450 | 0.0016 | 0.012 | 0.0181 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0315 | 0.131 |
Trypanosoma cruzi | O-6 methyl-guanine alkyl transferase, putative | 0.0134 | 0.1458 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.026 | 0.2882 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.2046 | 0.7612 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0012 | 0.0075 | 0.0046 |
Trypanosoma brucei | cytochrome P450, putative | 0.0025 | 0.0229 | 0.1479 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0279 | 0.0596 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0079 | 0.0842 | 0.0793 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0301 | 0.1242 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0016 | 0.012 | 0.0354 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0012 | 0.0075 | 0.0021 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0012 | 0.0086 | 0.0123 |
Schistosoma mansoni | cytochrome P450 | 0.0016 | 0.012 | 0.0253 |
Echinococcus multilocularis | geminin | 0.0186 | 0.2046 | 0.2003 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0209 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.01 | 0.0128 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0123 | 0.0264 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0016 | 0.0123 | 0.0069 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0315 | 0.0515 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0025 | 0.0229 | 0.0395 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0016 | 0.012 | 0.0333 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | ets-related | 0.0012 | 0.0075 | 0.008 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.012 | 0.0253 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0016 | 0.0123 | 0.0347 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0279 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0155 | 0.0273 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.0005 |
Brugia malayi | Cytochrome P450 family protein | 0.0016 | 0.012 | 0.0135 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0018 | 0.0153 | 0.0381 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0464 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0106 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0036 | 0.0356 | 0.0799 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0315 | 0.0997 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1045 | 0.2598 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0016 | 0.0123 | 0.0264 |
Echinococcus granulosus | lamin | 0.003 | 0.0279 | 0.113 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0023 | 0.0209 | 0.0309 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0098 | 0.1051 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0054 | 0.0007 |
Schistosoma mansoni | elf1 | 0.0012 | 0.0075 | 0.008 |
Loa Loa (eye worm) | fli-1 protein | 0.0241 | 0.2671 | 0.6845 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0079 | 0.0842 | 0.396 |
Mycobacterium ulcerans | methylated-DNA--protein-cysteine methyltransferase Ogt | 0.0407 | 0.4545 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0347 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0209 | 0.0559 |
Schistosoma mansoni | lamin | 0.003 | 0.0279 | 0.086 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0025 | 0.0229 | 0.0464 |
Brugia malayi | Ets-domain containing protein | 0.0079 | 0.0842 | 0.1545 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0054 | 0.1703 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0279 | 0.0445 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0209 | 0.0559 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0079 | 0.0842 | 0.2068 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0315 | 0.0262 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.01 | 0.0128 |
Leishmania major | cytochrome p450-like protein | 0.0016 | 0.012 | 0.0249 |
Echinococcus multilocularis | protein C ets 2 | 0.0012 | 0.0075 | 0.0021 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0464 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0256 | 0.2843 | 0.7296 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0016 | 0.0123 | 0.014 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0123 | 0.0142 |
Brugia malayi | Protein kinase domain containing protein | 0.0098 | 0.1051 | 0.1952 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0012 | 0.0075 | 0.0062 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0054 | 0.056 | 0.4912 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0315 | 0.0997 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0315 | 0.0262 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0279 | 0.086 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0279 | 0.0596 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.1051 | 0.7035 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0016 | 0.012 | 0.0154 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0016 | 0.0123 | 0.0069 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0016 | 0.0123 | 0.0347 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.3878 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.2046 | 0.7612 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0098 | 0.1051 | 0.7035 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | cytochrome P450 | 0.0016 | 0.012 | 0.0135 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0081 | 0.0858 | 0.4036 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.1051 | 1 |
Brugia malayi | Fli-1 protein | 0.0241 | 0.2671 | 0.5114 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0053 | 0.0006 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0012 | 0.0075 | 0.0106 |
Echinococcus multilocularis | musashi | 0.003 | 0.0279 | 0.0226 |
Schistosoma mansoni | ets | 0.0012 | 0.0075 | 0.008 |
Echinococcus multilocularis | 0.0016 | 0.012 | 0.0067 | |
Echinococcus granulosus | bloom syndrome protein | 0.0023 | 0.0209 | 0.078 |
Plasmodium vivax | SET domain protein, putative | 0.0033 | 0.0315 | 1 |
Onchocerca volvulus | 0.003 | 0.0279 | 0.0805 | |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0121 | 0.3851 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0016 | 0.0123 | 0.0188 |
Schistosoma mansoni | lamin | 0.003 | 0.0279 | 0.086 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | death domain containing protein | 0.0016 | 0.0123 | 0.0347 |
Mycobacterium leprae | PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA | 0.0407 | 0.4545 | 1 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0021 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0081 | 0.0858 | 0.0808 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | geminin | 0.0186 | 0.2046 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0123 | 0.019 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0228 | 0.2525 | 0.6465 |
Brugia malayi | Death domain containing protein | 0.0016 | 0.0123 | 0.014 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0012 | 0.0075 | 0.0021 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0054 | 0.0007 |
Onchocerca volvulus | 0.026 | 0.2883 | 1 | |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0229 | 0.0347 |
Onchocerca volvulus | 0.003 | 0.0279 | 0.0805 | |
Schistosoma mansoni | netrin receptor unc5 | 0.0016 | 0.0123 | 0.0264 |
Echinococcus multilocularis | ets variant gene 4 | 0.0012 | 0.0075 | 0.0021 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0012 | 0.0075 | 0.008 |
Mycobacterium ulcerans | DNA-methyltransferase (modification methylase) | 0.0054 | 0.056 | 0.1133 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0315 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0012 | 0.0086 | 0.0815 |
Chlamydia trachomatis | methylated-DNA protein-cysteine methyltransferase | 0.0134 | 0.1458 | 0.5 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0016 | 0.012 | 0.3811 |
Brugia malayi | hypothetical protein | 0.0133 | 0.1454 | 0.2739 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0016 | 0.012 | 0.0154 |
Echinococcus multilocularis | Ankyrin | 0.0016 | 0.0124 | 0.0071 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0012 | 0.0075 | 0.0062 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0279 | 0.113 |
Echinococcus granulosus | dual specificity | 0.0098 | 0.1051 | 0.5007 |
Schistosoma mansoni | ets-related | 0.0241 | 0.2671 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0016 | 0.012 | 0.0154 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0016 | 0.012 | 0.0249 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0012 | 0.0075 | 0.0021 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0012 | 0.0075 | 0.0021 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0098 | 0.1051 | 0.7035 |
Echinococcus multilocularis | bloom syndrome protein | 0.0023 | 0.0209 | 0.0156 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0229 | 0.1041 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0075 | 0.008 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0016 | 0.012 | 0.0154 |
Echinococcus multilocularis | dual specificity | 0.0098 | 0.1051 | 0.1003 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0016 | 0.012 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1045 | 0.2598 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0106 | 0.0052 |
Leishmania major | hypothetical protein, conserved | 0.0134 | 0.1458 | 1 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0021 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0012 | 0.0075 | 0.0062 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Serotonin receptor | 0.0462 | 0.5174 | 1 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0016 | 0.012 | 0.0154 |
Trypanosoma cruzi | O-6 methyl-guanine alkyl transferase, putative | 0.0134 | 0.1458 | 1 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0098 | 0.1051 | 1 |
Schistosoma mansoni | gabp alpha | 0.0079 | 0.0842 | 0.3014 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0016 | 0.012 | 0.0154 |
Brugia malayi | Ets-domain containing protein | 0.0012 | 0.0075 | 0.0046 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0016 | 0.012 | 0.0154 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0016 | 0.0124 | 0.027 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0016 | 0.012 | 0.0154 |
Onchocerca volvulus | Netrin receptor homolog | 0.0016 | 0.0123 | 0.0254 |
Entamoeba histolytica | protein kinase, putative | 0.0098 | 0.1051 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0016 | 0.012 | 0.0154 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0054 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0279 | 0.0445 |
Leishmania major | cytochrome p450-like protein | 0.0025 | 0.0229 | 0.1041 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0177 | 1 |
Echinococcus granulosus | Ankyrin | 0.0016 | 0.0124 | 0.0354 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0098 | 0.1051 | 0.2613 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0106 | 0.0262 |
Brugia malayi | Uncoordinated protein 44 | 0.0016 | 0.0123 | 0.014 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0016 | 0.012 | 0.0154 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | protein C ets 2 | 0.0012 | 0.0075 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0315 | 0.0689 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0315 | 0.0997 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0279 | 0.113 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0016 | 0.012 | 0.0154 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0012 | 0.0075 | 0.0106 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0016 | 0.012 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0123 | 0.0188 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0016 | 0.012 | 0.0249 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Log EC50 (functional) | = 6.12 | Effective concentration of the compound was determined against PI-Resistant HIV strain (M1) | ChEMBL. | 15771427 |
Log EC50 (functional) | = 7.32 | Effective concentration of the compound was determined against PI-Resistant HIV strain (M2) | ChEMBL. | 15771427 |
Log EC50 (functional) | = 7.37 | Effective concentration of the compound was determined as average activity on mutant HIV panel (AVMUT) | ChEMBL. | 15771427 |
Log EC50 (functional) | = 7.55 | Effective concentration of the compound was determined against PI-Resistant HIV strain (M3) | ChEMBL. | 15771427 |
Log EC50 (functional) | = 7.58 | Effective concentration of the compound was determined against PI-Resistant HIV strain (M4) | ChEMBL. | 15771427 |
Log EC50 (functional) | = 7.58 | Effective concentration of the compound was determined against PI-Resistant HIV strain (M5) | ChEMBL. | 15771427 |
Log EC50 (functional) | = 8.36000000000001 | Effective concentration of of the compound was determined against HIV Wild Type (IIIB) strain | ChEMBL. | 15771427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.