Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ratio (functional) | 0 | Ratio of the concentration of compound leading to a 50% inhibition of the rate of pig brain microtubule disassembly to that of of taxol (0.4 uM) was determined; ND=No data | ChEMBL. | 1672159 |
Ratio (functional) | = 30 | Ratio of the concentration leading to a 50% inhibition of the rate of pig brain microtubule disassembly to that of taxol (0.4 uM) was determined | ChEMBL. | 1672159 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.