Detailed information for compound 311297

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 793.091 | Formula: C48H68N6O4
  • H donors: 2 H acceptors: 4 LogP: 3.35 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN(CCC(=O)N1CCC[C@H]2[C@]31CC(=CC2Cc1c3ccc(=O)[nH]1)C)CCCCCCCCN(CCC(=O)N1CCC[C@H]2[C@]31CC(=CC2Cc1c3ccc(=O)[nH]1)C)C
  • InChi: 1S/C48H68N6O4/c1-33-27-35-29-41-39(15-17-43(55)49-41)47(31-33)37(35)13-11-23-53(47)45(57)19-25-51(3)21-9-7-5-6-8-10-22-52(4)26-20-46(58)54-24-12-14-38-36-28-34(2)32-48(38,54)40-16-18-44(56)50-42(40)30-36/h15-18,27-28,35-38H,5-14,19-26,29-32H2,1-4H3,(H,49,55)(H,50,56)/t35?,36?,37-,38-,47-,48-/m1/s1
  • InChiKey: XCDQISLHKSKFLH-AZGNAIHRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Acetylcholinesterase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) acetylcholinesterase 1 Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Brugia malayi Carboxylesterase family protein Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum Acetylcholinesterase 1 precursor, putative Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Get druggable targets OG5_126875 All targets in OG5_126875
Schistosoma japonicum ko:K01049 acetylcholinesterase [EC3.1.1.7], putative Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus multilocularis carboxylesterase 5A Get druggable targets OG5_126875 All targets in OG5_126875
Loa Loa (eye worm) carboxylesterase Get druggable targets OG5_126875 All targets in OG5_126875
Echinococcus granulosus acetylcholinesterase Get druggable targets OG5_126875 All targets in OG5_126875
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) Acetylcholinesterase   614 aa 602 aa 24.3 %
Onchocerca volvulus Putative nuclear protein Acetylcholinesterase   614 aa 577 aa 40.7 %
Onchocerca volvulus Carnitine O-palmitoyltransferase 2, mitochondrial homolog Acetylcholinesterase   614 aa 531 aa 39.7 %
Onchocerca volvulus Acetylcholinesterase   614 aa 632 aa 25.6 %
Echinococcus granulosus BC026374 protein S09 family Acetylcholinesterase   614 aa 642 aa 34.1 %
Onchocerca volvulus Acetylcholinesterase   614 aa 581 aa 27.0 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   614 aa 573 aa 30.5 %
Echinococcus multilocularis BC026374 protein (S09 family) Acetylcholinesterase   614 aa 642 aa 34.0 %
Drosophila melanogaster CG10175 gene product from transcript CG10175-RE Acetylcholinesterase   614 aa 547 aa 32.5 %
Brugia malayi Carboxylesterase family protein Acetylcholinesterase   614 aa 507 aa 26.4 %
Onchocerca volvulus Acetylcholinesterase   614 aa 583 aa 30.7 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   614 aa 570 aa 25.4 %
Loa Loa (eye worm) hypothetical protein Acetylcholinesterase   614 aa 574 aa 24.0 %
Echinococcus multilocularis neuroligin Acetylcholinesterase   614 aa 496 aa 24.0 %
Onchocerca volvulus Molybdopterin synthase catalytic subunit homolog Acetylcholinesterase   614 aa 564 aa 29.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0043 0.0078 0.037
Leishmania major glucose transporter, lmgt3 0.0019 0.0007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0037 0.006 0.0146
Trichomonas vaginalis helicase, putative 0.002 0.0009 0.0044
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0062 0.0087
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1393 0.412 0.5769
Schistosoma mansoni coup transcription factor 0.0198 0.0542 0.0759
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0034 0.0278
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0396 0.1096
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.012 0.029
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Loa Loa (eye worm) hypothetical protein 0.0039 0.0065 0.0156
Onchocerca volvulus 0.0335 0.0952 0.3758
Echinococcus granulosus lamin dm0 0.008 0.0189 0.0265
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0082 0.086
Echinococcus granulosus Solute carrier organic anion transporter family 0.0028 0.0032 0.0044
Brugia malayi G-protein coupled receptor 0.0334 0.0948 0.2624
Giardia lamblia Rab geranylgeranyltransferase 0.0166 0.0446 0.1081
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0133 0.0675
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Echinococcus granulosus solute carrier family 22 0.0019 0.0007 0.001
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0176 0.0476 0.1318
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0031 0.0041 0.0197
Onchocerca volvulus 0.0019 0.0007 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.0194 0.0528 0.2995
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.012 0.0714
Brugia malayi G protein-coupled receptor F59B2.13 0.0334 0.0948 0.2624
Echinococcus multilocularis FTZ F1 alpha 0.0198 0.0542 0.0542
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.005 0.0099 0.05
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.014 0.0368 0.386
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.0167 0.045 1
Loa Loa (eye worm) hypothetical protein 0.008 0.0189 0.0458
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0577 0.1676 1
Trypanosoma brucei Replication factor A protein 1 0.0033 0.0048 0.05
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0048 0.0092 0.0253
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Brugia malayi CHE-14 protein 0.0058 0.0121 0.0335
Loa Loa (eye worm) hypothetical protein 0.0121 0.0312 0.0756
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Onchocerca volvulus 0.0019 0.0005 0.0014
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.0215 0.0595
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.008 0.0187 0.0262
Giardia lamblia Fructose-bisphosphate aldolase 0.0577 0.1676 0.4068
Plasmodium falciparum cGMP-specific phosphodiesterase 0.017 0.0457 0.2606
Leishmania major glucose transporter, lmgt2 0.0019 0.0007 0.0071
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0081 0.0192 0.1094
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Onchocerca volvulus 0.0089 0.0215 0.0844
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0334 0.0948 0.0948
Echinococcus granulosus tm gpcr rhodopsin 0.0334 0.0948 0.1328
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0198 0.0542 0.0759
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.4794
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0169 0.0803
Echinococcus multilocularis insulin receptor 0.0047 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Brugia malayi photoreceptor-specific nuclear receptor 0.0198 0.0542 0.15
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0028 0.0132
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0602 0.1751 0.8334
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.012 0.0606
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0105 0.0262 0.0367
Echinococcus multilocularis g protein coupled receptor 0.0334 0.0948 0.0948
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.049 0.1189
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0198 0.0542 0.15
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0105 0.0262 0.0636
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0261
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0334 0.0948 0.1328
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0032 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.0311 0.0435
Echinococcus multilocularis pikachurin 0.0048 0.0092 0.0092
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0093 0.0229 0.0554
Brugia malayi neuropeptide F receptor 0.0334 0.0948 0.2624
Schistosoma mansoni hypothetical protein 0.0045 0.0084 0.0118
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0198 0.0542 0.0759
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0121 0.0311 0.0311
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0176 0.0476 0.0667
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0092 0.0225 0.0546
Brugia malayi GnHR receptor homolog 0.0788 0.2308 0.639
Onchocerca volvulus 0.0093 0.0229 0.0897
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0198 0.0543 0.3081
Loa Loa (eye worm) hypothetical protein 0.0081 0.0192 0.0465
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0028 0.0032 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0105 0.0262 0.0725
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis solute carrier family 22 0.0019 0.0007 0.0007
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0055 0.0077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0334 0.0948 0.0948
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.0183 0.0498 0.1207
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0081 0.0192 0.0913
Brugia malayi PAS domain containing protein 0.0193 0.0526 0.1456
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0138 0.1449
Trichomonas vaginalis fad synthetase, putative 0.0017 0 0.0001
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0082 0.0115
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni opsin-like receptor 0.0334 0.0948 0.1328
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.017 0.0457 0.0639
Toxoplasma gondii thioredoxin reductase 0.0037 0.006 0.0146
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.008 0.0113
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0198 0.0542 0.0759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.0324 0.0454
Onchocerca volvulus 0.0334 0.0948 0.3742
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0081 0.0191 0.0191
Schistosoma mansoni diflavin oxidoreductase 0.004 0.0069 0.0096
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.01 0.1048
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Trypanosoma brucei hypothetical protein, conserved 0.0181 0.049 0.5148
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Schistosoma mansoni hypothetical protein 0.038 0.1088 0.1524
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Onchocerca volvulus 0.0019 0.0007 0.0021
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0759 0.2221 0.3111
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0034 0.01
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0081 0.0191 0.0191
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0069 0.0155 0.0739
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Echinococcus granulosus cpg binding protein 0.0094 0.0231 0.0323
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Echinococcus granulosus dna polymerase kappa 0.0062 0.0133 0.0187
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0334 0.0948 0.2624
Trypanosoma cruzi hypothetical protein, conserved 0.017 0.0457 0.2314
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Schistosoma mansoni neuropeptide receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0078 0.0813
Brugia malayi Cytochrome P450 family protein 0.0085 0.0204 0.0564
Echinococcus multilocularis epidermal growth factor receptor 0.0148 0.0392 0.0392
Schistosoma mansoni biogenic amine (5HT) receptor 0.0334 0.0948 0.1328
Toxoplasma gondii aspartyl protease ASP1 0.0602 0.1751 0.425
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0198 0.0542 0.15
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0034 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Echinococcus granulosus alpha 1A adrenergic receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Entamoeba histolytica cysteine proteinase, putative 0.0194 0.0528 0.2995
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0155 0.0736
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Plasmodium falciparum serine repeat antigen 6 0.0081 0.0192 0.1094
Brugia malayi Carboxylesterase family protein 0.0082 0.0194 0.0536
Echinococcus multilocularis segment polarity protein dishevelled 0.0103 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0019 0.0007 0.0021
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0069 0.0155 0.0739
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0334 0.0948 0.1328
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0005 0.0014
Echinococcus multilocularis nuclear receptor nhr 48 0.0093 0.0229 0.0229
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0044
Mycobacterium leprae conserved hypothetical protein 0.0181 0.049 0.3999
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0192 0.0269
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0577 0.1676 1
Entamoeba histolytica cysteine proteinase, putative 0.0335 0.0952 0.558
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0192 0.0269
Echinococcus multilocularis carboxylesterase 5A 0.0082 0.0194 0.0194
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0105 0.0262 0.0636
Loa Loa (eye worm) hypothetical protein 0.017 0.0457 0.1108
Trypanosoma brucei cytochrome P450, putative 0.0064 0.0139 0.146
Loa Loa (eye worm) hypothetical protein 0.0065 0.0144 0.035
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0676 0.1972 0.2762
Onchocerca volvulus 0.0067 0.0148 0.058
Loa Loa (eye worm) inositol-1 0.0074 0.0169 0.041
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0192 0.0465
Echinococcus granulosus g-protein coupled receptor 0.0334 0.0948 0.1328
Plasmodium falciparum replication protein A1, large subunit 0.0033 0.0048 0.0272
Schistosoma mansoni hypothetical protein 0.0334 0.0948 0.1328
Mycobacterium leprae Possible regulatory protein 0.005 0.0099 0.0807
Trypanosoma brucei sugar transporter, putative 0.0019 0.0007 0.0071
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0093 0.0229 0.032
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0192 0.0913
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.012 0.266
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0028 0.0032 0.0044
Schistosoma mansoni agrin 0.0019 0.0005 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0192 0.053
Loa Loa (eye worm) hypothetical protein 0.0105 0.0262 0.0636
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.005 0.0098 0.0137
Brugia malayi Cytochrome P450 family protein 0.0064 0.0139 0.0385
Mycobacterium ulcerans integral membrane transport protein 0.0019 0.0007 0.0057
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Schistosoma mansoni sugar transporter 0.0019 0.0007 0.001
Schistosoma mansoni thyroid hormone receptor 0.0323 0.0917 0.1284
Brugia malayi Cathepsin L-like precursor 0.0335 0.0952 0.2635
Brugia malayi Nuclear hormone receptor-like 1 0.0105 0.0262 0.0725
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0311 0.2535
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Loa Loa (eye worm) hypothetical protein 0.0082 0.0194 0.047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0144 0.035
Mycobacterium tuberculosis Probable oxidoreductase 0.029 0.0819 0.2403
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0048 0.0116
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0031 0.0041 0.0208
Loa Loa (eye worm) hypothetical protein 0.0181 0.049 0.1189
Trypanosoma cruzi cysteine protease, putative 0.0194 0.0528 0.2678
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.017 0.0457 0.0639
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0156 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0194 0.0528 0.2515
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Schistosoma mansoni dishevelled 0.0093 0.0228 0.0319
Brugia malayi ShTK domain containing protein 0.0089 0.0215 0.0595
Echinococcus multilocularis dnaJ subfamily B 0.0848 0.2489 0.2489
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0032 0.0087
Mycobacterium ulcerans glutaminase 0.0278 0.078 0.6366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0192 0.0913
Loa Loa (eye worm) hypothetical protein 0.0602 0.1751 0.425
Onchocerca volvulus 0.0334 0.0948 0.3742
Schistosoma mansoni cpg binding protein 0.0094 0.0231 0.0323
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0305 0.0739
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.017 0.0457 0.0457
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Loa Loa (eye worm) melatonin receptor type 1A 0.0334 0.0948 0.2301
Echinococcus granulosus neurogenic locus notch protein 0.0048 0.0092 0.0129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0335 0.0952 0.5435
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0334 0.0948 0.1328
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0192 0.0465
Echinococcus granulosus FTZ F1 alpha 0.0198 0.0542 0.0759
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0034 0.0278
Toxoplasma gondii transporter, major facilitator family protein 0.0019 0.0007 0.0016
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0334 0.0948 0.1328
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0019 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0034 0.0278
Echinococcus granulosus allatostatin A receptor 0.0334 0.0948 0.1328
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0179 0.0484 0.1174
Echinococcus multilocularis synaptic vesicle 2 protein 0.002 0.0008 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.0335 0.0952 0.2635
Brugia malayi Pepsin A precursor 0.0179 0.0484 0.1339
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1393 0.412 0.412
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Brugia malayi RNA binding protein 0.0069 0.0156 0.043
Echinococcus multilocularis cathepsin L cysteine protease 0.0335 0.0952 0.0952
Onchocerca volvulus 0.0019 0.0007 0.0021
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0602 0.1751 0.1751
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Brugia malayi intermediate filament protein 0.008 0.0189 0.0522
Onchocerca volvulus 0.0335 0.0952 0.3758
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0066 0.0145 0.0692
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0051 0.01 0.0507
Loa Loa (eye worm) glutaminase 2 0.0278 0.078 0.1893
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Loa Loa (eye worm) hypoxia-induced factor 1 0.0596 0.1735 0.4211
Leishmania major hypothetical protein, conserved 0.0019 0.0007 0.0071
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.017 0.0457 0.0639
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Loa Loa (eye worm) hypothetical protein 0.014 0.0368 0.0892
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.1393 0.412 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0334 0.0948 0.3742
Onchocerca volvulus 0.0043 0.0078 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Schistosoma mansoni sugar transporter 0.0019 0.0007 0.001
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0007 0.0071
Toxoplasma gondii aspartyl protease ASP3 0.0515 0.149 0.3617
Plasmodium vivax polyprenol reductase, putative 0.0065 0.0144 0.0823
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.014 0.0368 0.386
Onchocerca volvulus 0.0334 0.0948 0.3742
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Mycobacterium ulcerans hypothetical protein 0.0181 0.049 0.3999
Onchocerca volvulus 0.0019 0.0007 0.0021
Plasmodium falciparum plasmepsin II 0.0602 0.1751 1
Toxoplasma gondii exonuclease III APE 0.0057 0.012 0.029
Brugia malayi Dopamine receptor protein 2 0.0334 0.0948 0.2624
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0144 0.0687
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0081 0.0192 0.1094
Giardia lamblia Cathepsin B precursor 0.0265 0.0742 0.1802
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.0091 0.0219
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0081 0.0192 0.0465
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0305 0.0739
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0192 0.053
Loa Loa (eye worm) cysteine protease 0.0335 0.0952 0.231
Plasmodium vivax hexose transporter 0.0019 0.0007 0.0038
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0225 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0029 0.0136
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0181 0.049 0.1439
Onchocerca volvulus Huntingtin homolog 0.0121 0.0312 0.1226
Plasmodium vivax aspartyl protease, putative 0.0515 0.149 0.851
Loa Loa (eye worm) hypothetical protein 0.0096 0.0236 0.0573
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0034 0.0048
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0081 0.0192 0.1094
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0093 0.0229 0.0229
Plasmodium vivax vivapain-2 0.0335 0.0952 0.5435
Plasmodium falciparum hexose transporter 0.0019 0.0007 0.0038
Loa Loa (eye worm) sugar transporter 0.0019 0.0007 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.017 0.0457 0.2314
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0139 0.1135
Schistosoma mansoni myosin xvIII 0.0334 0.0948 0.1328
Echinococcus multilocularis isocitrate dehydrogenase 0.0063 0.0138 0.0138
Brugia malayi Papain family cysteine protease containing protein 0.0194 0.0528 0.1462
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Toxoplasma gondii sugar transporter ST2 0.0019 0.0007 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Loa Loa (eye worm) steroid hormone receptor 0.0198 0.0542 0.1315
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0031 0.0041 0.0197
Schistosoma mansoni single-minded 0.0193 0.0526 0.0737
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus granulosus hypothetical protein 0.0334 0.0948 0.1328
Loa Loa (eye worm) hypothetical protein 0.0048 0.0092 0.0222
Brugia malayi Sugar transporter family protein 0.0019 0.0007 0.0019
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.005 0.0099 0.0099
Loa Loa (eye worm) glutathione reductase 0.0037 0.006 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Loa Loa (eye worm) intermediate filament protein 0.008 0.0189 0.0458
Loa Loa (eye worm) hypothetical protein 0.0647 0.1885 0.4575
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.005 0.0099 0.0471
Echinococcus granulosus epidermal growth factor receptor 0.0148 0.0392 0.055
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Trichomonas vaginalis esterase, putative 0.0181 0.049 0.2333
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0034 0.01
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0035 0.0169
Onchocerca volvulus 0.0081 0.0192 0.0752
Loa Loa (eye worm) hypothetical protein 0.0083 0.0196 0.0475
Trypanosoma brucei cAMP-specific phosphodiesterase 0.017 0.0457 0.4794
Schistosoma mansoni nuclear hormone receptor 0.0093 0.0229 0.032
Giardia lamblia Cathepsin L-like protease 0.0081 0.0192 0.0465
Onchocerca volvulus 0.0049 0.0095 0.037
Loa Loa (eye worm) POT family protein 0.004 0.0068 0.0164
Loa Loa (eye worm) hypothetical protein 0.0181 0.049 0.1189
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0034 0.0278
Entamoeba histolytica type A flavoprotein, putative 0.0031 0.0041 0.0023
Echinococcus granulosus Protein patched homolog 1 0.0058 0.0121 0.017
Schistosoma mansoni hypothetical protein 0.0334 0.0948 0.1328
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0334 0.0948 0.2301
Loa Loa (eye worm) hypothetical protein 0.1178 0.3476 0.8438
Brugia malayi Cathepsin L-like precursor 0.0223 0.0615 0.1703
Echinococcus multilocularis neuropeptide receptor A26 0.0803 0.2352 0.2352
Trypanosoma cruzi hypothetical protein, conserved 0.0181 0.049 0.2484
Echinococcus granulosus neuropeptide Y receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.01 0.0242
Giardia lamblia Kinase, CMGC MAPK 0.005 0.01 0.0242
Brugia malayi cytochrome P450 0.0028 0.0034 0.0094
Leishmania major hypothetical protein, conserved 0.0181 0.049 0.5148
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0138 0.1449
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0063 0.0138 0.0194
Echinococcus granulosus segment polarity protein dishevelled 0.0103 0.0258 0.0361
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Schistosoma mansoni cathepsin B (C01 family) 0.0081 0.0192 0.0269
Brugia malayi Cathepsin L-like precursor 0.0335 0.0952 0.2635
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.012 0.0501
Brugia malayi SPARC precursor 0.0019 0.0005 0.0014
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0167 0.0234
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0065 0.0144 0.035
Mycobacterium tuberculosis Probable lipase LipE 0.0181 0.049 0.1439
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0198 0.0542 0.0759
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0034 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0093 0.0229 0.032
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0194 0.0528 0.074
Brugia malayi hypothetical protein 0.0179 0.0484 0.1339
Onchocerca volvulus 0.0181 0.049 0.1931
Echinococcus granulosus slit 2 protein 0.0048 0.0092 0.0129
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0198 0.0542 0.0542
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0005 0.0012
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0676 0.1972 0.2762
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Schistosoma mansoni tyrosine kinase 0.0148 0.0392 0.055
Onchocerca volvulus 0.0089 0.0215 0.0844
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0543 0.2582
Echinococcus multilocularis cathepsin b 0.0676 0.1972 0.1972
Loa Loa (eye worm) hypothetical protein 0.038 0.1088 0.2641
Echinococcus multilocularis sterol regulatory element binding protein 0.0058 0.0121 0.0121
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0055 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0194 0.0528 0.5549
Onchocerca volvulus 0.0335 0.0952 0.3758
Onchocerca volvulus 0.0335 0.0952 0.3758
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni hypothetical protein 0.0848 0.2489 0.3486
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0085 0.0203 0.0597
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0034 0.01
Mycobacterium ulcerans short chain dehydrogenase 0.029 0.0819 0.668
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0105 0.0262 0.0367
Echinococcus multilocularis expressed protein 0.0019 0.0005 0.0005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0632 0.1841 0.4467
Trypanosoma cruzi major cysteine proteinase, putative 0.0081 0.0192 0.0971
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0156 0.043
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0065 0.0144 0.0144
Loa Loa (eye worm) acetylcholinesterase 1 0.0082 0.0194 0.047
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.017 0.0457 0.0457
Loa Loa (eye worm) hypothetical protein 0.0089 0.0215 0.0521
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.005 0.0099 0.0019
Mycobacterium tuberculosis Conserved protein 0.0181 0.049 0.1439
Plasmodium vivax aspartyl proteinase, putative 0.0179 0.0484 0.2762
Echinococcus granulosus g protein coupled receptor 0.0334 0.0948 0.1328
Loa Loa (eye worm) hypothetical protein 0.0081 0.0192 0.0465
Echinococcus granulosus GPCR family 2 0.0176 0.0476 0.0667
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0198 0.0542 0.0542
Schistosoma mansoni opsin-like receptor 0.0334 0.0948 0.1328
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0198 0.0542 0.0759
Plasmodium vivax unspecified product 0.0081 0.0192 0.1094
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Echinococcus granulosus aryl hydrocarbon receptor 0.005 0.0099 0.0139
Schistosoma mansoni hypothetical protein 0.0069 0.0155 0.0218
Brugia malayi Papain family cysteine protease containing protein 0.0194 0.0528 0.1462
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0139 0.0139
Trichomonas vaginalis sugar transport protein, putative 0.0019 0.0007 0.0033
Schistosoma mansoni nuclear receptor nhr-48 0.0093 0.0229 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0194 0.0528 0.2515
Plasmodium falciparum nitric oxide synthase, putative 0.0081 0.0191 0.1087
Schistosoma mansoni organic anion transporter 0.0028 0.0032 0.0044
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0334 0.0948 0.0948
Brugia malayi Eukaryotic aspartyl protease family protein 0.0179 0.0484 0.1339
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0334 0.0948 0.1328
Echinococcus multilocularis thyroid hormone receptor alpha 0.0323 0.0917 0.0917
Mycobacterium ulcerans esterase/lipase LipP 0.0181 0.049 0.3999
Leishmania major myo-inositol/proton symporter (MIT) 0.0019 0.0007 0.0071
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2606
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0007 0.001
Entamoeba histolytica type A flavoprotein, putative 0.0031 0.0041 0.0023
Giardia lamblia Cathepsin B precursor 0.0081 0.0192 0.0465
Plasmodium vivax plasmepsin V, putative 0.0179 0.0484 0.2762
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0063 0.0138 0.0699
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0034 0.0082
Giardia lamblia Nitric oxide synthase, inducible 0.0072 0.0163 0.0395
Echinococcus multilocularis 0.0028 0.0034 0.0034
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.006 0.0146
Schistosoma mansoni biogenic amine receptor 0.0334 0.0948 0.1328
Trypanosoma brucei cAMP-specific phosphodiesterase 0.017 0.0457 0.4794
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0019 0.0007 0.0038
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0265 0.0742 0.3764
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0034 0.0172
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0066 0.0145 0.0352
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus granulosus neuropeptide s receptor 0.0803 0.2352 0.3294
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Echinococcus multilocularis cpg binding protein 0.0094 0.0231 0.0231
Mycobacterium leprae putative cytochrome p450 0.0028 0.0034 0.0278
Leishmania major glucose transporter/membrane transporter D2, putative 0.0019 0.0007 0.0071
Toxoplasma gondii cathepsin B 0.0265 0.0742 0.1802
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1223 0.3612 0.3612
Onchocerca volvulus 0.0019 0.0007 0.0021
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Echinococcus multilocularis allatostatin A receptor 0.0334 0.0948 0.0948
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0198 0.0542 0.15
Brugia malayi glutathione reductase 0.0037 0.006 0.0167
Leishmania major protein kinase, putative 0.0055 0.0112 0.1175
Trichomonas vaginalis CMGC family protein kinase 0.005 0.01 0.0476
Echinococcus multilocularis lamin dm0 0.008 0.0189 0.0189
Echinococcus granulosus cathepsin l1 0.0335 0.0952 0.1333
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0066 0.0145 0.0692
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Entamoeba histolytica cysteine proteinase, putative 0.0194 0.0528 0.2995
Brugia malayi Thioredoxin reductase 0.0037 0.006 0.0167
Loa Loa (eye worm) hypothetical protein 0.0676 0.1972 0.4787
Loa Loa (eye worm) hypothetical protein 0.0179 0.0484 0.1174
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0041 0.0058
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.017 0.0457 0.0457
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Onchocerca volvulus 0.0181 0.049 0.1931
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.01 0.1048
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0334 0.0948 0.0948
Schistosoma mansoni glucose transport protein 0.0019 0.0007 0.001
Mycobacterium ulcerans lipase LipD 0.0181 0.049 0.3999
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1393 0.412 0.5769
Toxoplasma gondii histone lysine methyltransferase SET1 0.0176 0.0475 0.1152
Schistosoma mansoni hypothetical protein 0.0334 0.0948 0.1328
Loa Loa (eye worm) major facilitator superfamily transporter 0.0019 0.0007 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Brugia malayi Cytochrome P450 family protein 0.0028 0.0034 0.0094
Plasmodium falciparum serine repeat antigen 9 0.0081 0.0192 0.1094
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0602 0.1751 0.425
Loa Loa (eye worm) RNA binding protein 0.0069 0.0156 0.0377
Giardia lamblia Hypothetical protein 0.017 0.0457 0.1108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0029 0.0136
Echinococcus granulosus serotonin receptor 0.0334 0.0948 0.1328
Loa Loa (eye worm) hypothetical protein 0.0081 0.0192 0.0465
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Loa Loa (eye worm) aspartyl protease 6 0.0179 0.0484 0.1174
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0543 0.2582
Loa Loa (eye worm) FAD binding domain-containing protein 0.005 0.0098 0.0238
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0334 0.0948 0.0948
Entamoeba histolytica cysteine proteinase 1, putative 0.0194 0.0528 0.2995
Toxoplasma gondii ABC1 family protein 0.0181 0.049 0.1189
Loa Loa (eye worm) hypothetical protein 0.0035 0.0055 0.0132
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0043 0.0078 0.0109
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.01 0.0506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0063 0.0298
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.1223 0.3612 0.5059
Brugia malayi major facilitator superfamily protein 0.0019 0.0007 0.0019
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0265 0.0742 0.104
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.002 0.0008 0.0062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0325 0.0922 0.1291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0054 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0093 0.0229 0.032
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Brugia malayi Dopamine receptor protein 1 0.0334 0.0948 0.2624
Plasmodium vivax unspecified product 0.0112 0.0285 0.1629
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0225 0.0315
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0384 0.0537
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0085 0.0203 0.1659
Echinococcus multilocularis neuropeptide Y receptor 0.0334 0.0948 0.0948
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0138 0.0138
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0034 0.01
Onchocerca volvulus 0.0335 0.0952 0.3758
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0194 0.0528 0.2678
Trypanosoma cruzi Replication factor A protein 1 0.0033 0.0048 0.0241
Echinococcus multilocularis Niemann Pick C1 protein 0.0058 0.0121 0.0121
Schistosoma mansoni nuclear hormone receptor 0.0093 0.0229 0.032
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0078 0.0813
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0082 0.0199
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Schistosoma mansoni adenoreceptor 0.0334 0.0948 0.1328
Giardia lamblia Cathepsin L precursor 0.0081 0.0192 0.0465
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0251 0.1431
Plasmodium falciparum phosphodiesterase gamma, putative 0.017 0.0457 0.2606
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.014 0.0368 0.1863
Brugia malayi ecdysteroid receptor 0.0862 0.253 0.7005
Trypanosoma cruzi cysteine peptidase, putative 0.0335 0.0952 0.4826
Mycobacterium tuberculosis Conserved protein 0.0181 0.049 0.1439
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0133 0.0675
Echinococcus granulosus dnaJ subfamily B 0.0848 0.2489 0.3486
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Schistosoma mansoni neuropeptide F-like receptor 0.0334 0.0948 0.1328
Schistosoma mansoni biogenic amine (5HT) receptor 0.0334 0.0948 0.1328
Leishmania major hypothetical protein, conserved 0.0018 0.0002 0.0016
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0139 0.1458
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0192 0.0913
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Brugia malayi MAP kinase sur-1 0.005 0.01 0.0276
Brugia malayi bHLH-PAS transcription factor 0.0143 0.0376 0.104
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0002 0.0003
Giardia lamblia Cathepsin B precursor 0.0081 0.0192 0.0465
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0103 0.0258 0.0712
Loa Loa (eye worm) cytochrome P450 0.0028 0.0034 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0034 0.01
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0081 0.0191 0.2
Plasmodium vivax plasmepsin IV, putative 0.0602 0.1751 1
Schistosoma mansoni tyrosine kinase 0.0047 0.0091 0.0127
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0043 0.0078 0.0392
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0081 0.0191 0.2
Loa Loa (eye worm) neuropeptide F receptor 0.0334 0.0948 0.2301
Toxoplasma gondii aspartyl protease 0.0179 0.0484 0.1174
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0192 0.0913
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0081 0.0192 0.1094
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0181 0.049 0.0686
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0192 0.0269
Echinococcus granulosus segment polarity protein dishevelled 0.0103 0.0258 0.0361
Echinococcus granulosus Nuclear hormone receptor HR96 0.0093 0.0229 0.032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0093 0.0229 0.0897
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.0183 0.0498 0.0697
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0034 0.0278
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0198 0.0542 0.15
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0192 0.0465
Echinococcus granulosus Niemann Pick C1 protein 0.0058 0.0121 0.017
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.017 0.0457 0.1263
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0065 0.0144 0.035
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Echinococcus multilocularis neurogenic locus notch protein 0.0048 0.0092 0.0092
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0334 0.0948 0.2624
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0557 0.1615 0.3921
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0034 0.0278
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0055 0.0104
Brugia malayi Nuclear hormone receptor-like 1 0.0198 0.0542 0.15
Echinococcus multilocularis dro:myosuppressin receptor 0.0334 0.0948 0.0948
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0093 0.0229 0.0897
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0029 0.0136
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus multilocularis microtubule associated protein 2 0.1363 0.403 0.403
Giardia lamblia Cathepsin L precursor 0.0081 0.0192 0.0465
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0676 0.1972 0.2762
Plasmodium vivax aspartyl proteinase, putative 0.0602 0.1751 1
Schistosoma mansoni replication factor A 1 rfa1 0.0069 0.0155 0.0218
Trypanosoma cruzi major cysteine proteinase, putative 0.0081 0.0192 0.0971
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.017 0.0457 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Brugia malayi cathepsin L precursor 0.0081 0.0192 0.053
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Plasmodium vivax hypothetical protein, conserved 0.0181 0.049 0.2798
Trypanosoma cruzi cysteine proteinase, putative 0.0194 0.0528 0.2678
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.012 0.1255
Trichomonas vaginalis molybdopterin- binding protein, putative 0.0017 0 0.0001
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0334 0.0948 0.0948
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0457 0.2173
Schistosoma mansoni hypothetical protein 0.0176 0.0476 0.0667
Loa Loa (eye worm) ShTK domain-containing protein 0.0089 0.0215 0.0521
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0058 0.0121 0.017
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0019 0.0007 0.0007
Brugia malayi hypothetical protein 0.1178 0.3476 0.9624
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0169 0.0237
Brugia malayi major facilitator superfamily protein 0.0019 0.0007 0.0019
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0082 0.086
Echinococcus granulosus jun protein 0.0085 0.0203 0.0284
Entamoeba histolytica cysteine protease, putative 0.0081 0.0192 0.0941
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0251 0.2633
Mycobacterium tuberculosis Probable hydrolase 0.0181 0.049 0.1439
Brugia malayi nuclear hormone receptor family member nhr-6 0.0093 0.0229 0.0632
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0133 0.0675
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0156 0.0218
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0034 0.0355
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.017 0.0457 0.2314
Schistosoma mansoni thyroid hormone receptor 0.0323 0.0917 0.1284
Loa Loa (eye worm) hypothetical protein 0.0037 0.0061 0.0146
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0396 0.0555
Onchocerca volvulus 0.0019 0.0007 0.0021
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0065 0.0144 0.0651
Plasmodium falciparum plasmepsin I 0.0602 0.1751 1
Toxoplasma gondii cathepsin CPC1 0.0081 0.0192 0.0465
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0543 0.275
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0192 0.0752
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Brugia malayi Carboxylesterase family protein 0.0082 0.0194 0.0536
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0034 0.0278
Onchocerca volvulus 0.0089 0.0215 0.0845
Leishmania major glucose transporter, lmgt1 0.0019 0.0007 0.0071
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0166 0.0446 0.1233
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0198 0.0542 0.0542
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.017 0.0457 0.0457
Loa Loa (eye worm) hypothetical protein 0.0335 0.0952 0.231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0044
Echinococcus granulosus pikachurin 0.0048 0.0092 0.0129
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis neuropeptide s receptor 0.0803 0.2352 0.2352
Giardia lamblia Cysteine protease 0.0081 0.0192 0.0465
Plasmodium falciparum plasmepsin III 0.0179 0.0484 0.2762
Brugia malayi replication factor A 73 kDa subunit 0.0069 0.0155 0.0429
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0133 0.0675
Brugia malayi Latrophilin receptor protein 2 0.0176 0.0476 0.1318
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0034 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0334 0.0948 0.2301
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.0091 0.0127
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0198 0.0542 0.0759
Loa Loa (eye worm) hypothetical protein 0.1393 0.412 1
Brugia malayi hypothetical protein 0.0096 0.0236 0.0654
Loa Loa (eye worm) flavodoxin family protein 0.0031 0.0041 0.01
Schistosoma mansoni follistatin 0.0019 0.0005 0.0008
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0194 0.0528 0.074
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.014 0.0368 0.1017
Loa Loa (eye worm) TK/EGFR protein kinase 0.0148 0.0392 0.0952
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0602 0.1751 0.2452
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Onchocerca volvulus 0.008 0.0189 0.074
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0012
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0034 0.01
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0121 0.0311 0.0435
Toxoplasma gondii hypothetical protein 0.0123 0.0317 0.0768
Plasmodium falciparum glutathione reductase 0.0037 0.006 0.0344
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0031 0.0041 0.0235
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0099 0.0471
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0181 0.049 0.1189
Plasmodium falciparum plasmepsin IX 0.0515 0.149 0.851
Brugia malayi FAD binding domain containing protein 0.005 0.0098 0.0271
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Giardia lamblia Hypothetical protein 0.0081 0.0192 0.0465
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Echinococcus multilocularis g protein coupled receptor 0.0334 0.0948 0.0948
Plasmodium falciparum plasmepsin VI 0.0602 0.1751 1
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.017 0.0457 0.0457
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.0215 0.0595
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.0167 0.045 0.2142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0261
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.005 0.0099 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Entamoeba histolytica cysteine proteinase, putative 0.0223 0.0615 0.3526
Brugia malayi Tachykinin-like peptides receptor 99D 0.0334 0.0948 0.2624
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0334 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0176 0.0476 0.1155
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.0183 0.0498 0.1377
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0043 0.0078 0.0244
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0139 0.0337
Brugia malayi Cytochrome P450 family protein 0.0064 0.0139 0.0385
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0019 0.0007 0.0057
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Brugia malayi nuclear receptor RXR 0.0105 0.0262 0.0725
Brugia malayi putative neuropeptide receptor 0.0334 0.0948 0.2624
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0007 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0043 0.0078 0.0078
Brugia malayi FAD binding domain containing protein 0.0081 0.0191 0.0527
Trypanosoma brucei cysteine peptidase C (CPC) 0.0265 0.0742 0.7798
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0144 0.0687
Schistosoma mansoni transcription factor btf3 0.0069 0.0155 0.0217
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.01 0.1048
Echinococcus multilocularis follistatin 0.0019 0.0005 0.0005
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0082 0.0272
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0676 0.1972 0.2762
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0034 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1155 0.3407 1
Brugia malayi Pre-SET motif family protein 0.0092 0.0225 0.0623
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0166 0.0446 0.1081
Mycobacterium tuberculosis Conserved protein 0.0181 0.049 0.1439
Echinococcus multilocularis 0.0046 0.0086 0.0086
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0034 0.01
Brugia malayi hypoxia-induced factor 1 0.0596 0.1735 0.4803
Loa Loa (eye worm) CYP4Cod1 0.0064 0.0139 0.0337
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0146 0.1192
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.005 0.0099 0.0139
Trypanosoma cruzi p450 reductase, putative 0.0081 0.0191 0.0965
Schistosoma mansoni sugar transporter 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Toxoplasma gondii OB-fold nucleic acid binding domain-containing protein 0.0017 0.0001 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0176 0.0476 0.0667
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0025 0.0025
Plasmodium falciparum serine repeat antigen 2 0.0081 0.0192 0.1094
Onchocerca volvulus 0.0019 0.0007 0.0021
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0166 0.0446 0.1081
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0192 0.0913
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0334 0.0948 0.1328
Leishmania major p450 reductase, putative 0.0081 0.0191 0.2
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0012
Brugia malayi hypothetical protein 0.0065 0.0144 0.0397
Loa Loa (eye worm) isocitrate dehydrogenase 0.0063 0.0138 0.0335
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0051 0.0103 0.0519
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.012 0.0168
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2606
Echinococcus multilocularis cathepsin L 0.0194 0.0528 0.0528
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0009 0.0044
Giardia lamblia Cathepsin B precursor 0.0081 0.0192 0.0465
Entamoeba histolytica hypothetical protein 0.0289 0.0816 0.4748
Brugia malayi hypothetical protein 0.0028 0.0032 0.0087
Echinococcus granulosus G protein coupled receptor 139 0.0334 0.0948 0.1328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0034 0.0278
Echinococcus granulosus 7tm_1 domain containing protein 0.0334 0.0948 0.1328
Entamoeba histolytica cysteine protease, putative 0.0081 0.0192 0.0941
Echinococcus granulosus sterol regulatory element binding protein 0.0058 0.0121 0.017
Brugia malayi hypothetical protein 0.0019 0.0007 0.0019
Leishmania major cAMP-specific phosphodiesterase, putative 0.017 0.0457 0.4794
Brugia malayi cathepsin F-like cysteine proteinase 0.0081 0.0192 0.053
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0081 0.0192 0.0465
Schistosoma mansoni hypothetical protein 0.024 0.0668 0.0936
Echinococcus granulosus survival motor neuron protein 1 0.1178 0.3476 0.4869
Loa Loa (eye worm) beta-lactamase 0.0181 0.049 0.1189
Onchocerca volvulus 0.0334 0.0948 0.3742
Onchocerca volvulus 0.0179 0.0484 0.1906
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0034 0.01
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0192 0.0524 0.0734
Trypanosoma cruzi hypothetical protein, conserved 0.017 0.0457 0.2314
Brugia malayi tailless protein 0.0093 0.0229 0.0632
Brugia malayi aspartic protease BmAsp-2, identical 0.0179 0.0484 0.1339
Toxoplasma gondii aldehyde dehydrogenase 0.0121 0.0311 0.0754
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Trypanosoma brucei unspecified product 0.0024 0.0022 0.0227
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.017 0.0457 0.0639
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0043 0.0078 0.0442
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0169 0.0805
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.005 0.0099 0.0471
Entamoeba histolytica cysteine proteinase 2 0.0194 0.0528 0.2995
Echinococcus multilocularis neuropeptide receptor 0.0334 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0541 0.157 0.381
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.017 0.0457 0.2314
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0265 0.0742 0.7798
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0034 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Brugia malayi steroid hormone receptor 0.0198 0.0542 0.15
Loa Loa (eye worm) hypothetical protein 0.0103 0.0258 0.0624
Echinococcus multilocularis somatostatin receptor 0.0334 0.0948 0.0948
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0094 0.0232 0.068
Treponema pallidum fructose-bisphosphate aldolase 0.0577 0.1676 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0166 0.0446 0.2121
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Plasmodium vivax serine-repeat antigen (SERA) 0.0081 0.0192 0.1094
Echinococcus granulosus biogenic amine 5HT receptor 0.0334 0.0948 0.1328
Echinococcus multilocularis tumor protein p63 0.0334 0.095 0.095
Echinococcus multilocularis musashi 0.008 0.0189 0.0189
Brugia malayi Cathepsin L-like precursor 0.0112 0.0285 0.079
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0018
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0169 0.0805
Brugia malayi Steroid receptor seven-up type 2 0.0198 0.0542 0.15
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Echinococcus granulosus somatostatin receptor 0.0334 0.0948 0.1328
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0114 0.1194
Entamoeba histolytica hypothetical protein 0.0289 0.0816 0.4748
Trypanosoma cruzi cysteine peptidase, putative 0.0112 0.0285 0.1446
Schistosoma mansoni glucose transport protein 0.0019 0.0007 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0038 0.0182
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0192 0.0465
Echinococcus granulosus nuclear receptor nhr 48 0.0093 0.0229 0.032
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.017 0.0457 0.2173
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.0001 0.0002
Brugia malayi Cathepsin L-like precursor 0.0335 0.0952 0.2635
Entamoeba histolytica hypothetical protein 0.0069 0.0155 0.0714
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0055 0.0161
Schistosoma mansoni nuclear receptor 0.0093 0.0229 0.032
Loa Loa (eye worm) hypothetical protein 0.0092 0.0225 0.0546
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0077 0.0187
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0198 0.0543 0.5698
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0094 0.0232 0.1891
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0031 0.0041 0.0208
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0155 0.1623
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0012
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Schistosoma mansoni hypothetical protein 0.0289 0.0816 0.1142
Onchocerca volvulus Huntingtin homolog 0.0121 0.0312 0.1226
Trypanosoma brucei DNA polymerase eta, putative 0.0035 0.0055 0.0572
Schistosoma mansoni lamin 0.008 0.0189 0.0265
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0085 0.0203 0.0597
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Plasmodium falciparum cGMP-specific phosphodiesterase 0.017 0.0457 0.2606
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0311 0.2535
Echinococcus multilocularis G protein coupled receptor 139 0.0334 0.0948 0.0948
Echinococcus multilocularis cysteine protease 0.0335 0.0952 0.0952
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0334 0.0948 0.2624
Giardia lamblia Cathepsin B precursor 0.0265 0.0742 0.1802
Onchocerca volvulus 0.0019 0.0007 0.0021
Onchocerca volvulus 0.0089 0.0215 0.0844
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0251 0.1271
Toxoplasma gondii sugar transporter ST1 0.0019 0.0007 0.0016
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0104 0.0253
Leishmania major cytochrome P450 reductase, putative 0.0072 0.0163 0.1711
Brugia malayi Serotonin receptor 0.0334 0.0948 0.2624
Giardia lamblia Cysteine protease 0.0081 0.0192 0.0465
Brugia malayi hypothetical protein 0.0289 0.0816 0.2258
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0167 0.0167
Trichomonas vaginalis adenylate cyclase, putative 0.005 0.0099 0.0471
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0055 0.0276
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0082 0.0227
Onchocerca volvulus 0.0198 0.0542 0.2136
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2606
Plasmodium vivax SET domain protein, putative 0.0092 0.0225 0.1285
Echinococcus granulosus cathepsin L 0.0194 0.0528 0.074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0198 0.0542 0.1315
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0155 0.0882
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0335 0.0952 0.5435
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0094 0.0232 0.068
Echinococcus multilocularis g-protein coupled receptor 0.0334 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Leishmania major cytochrome p450-like protein 0.0064 0.0139 0.146
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.008 0.0194
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0007 0.0033
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0002 0.0004
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0081 0.0191 0.1555
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.017 0.0457 0.2173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Echinococcus granulosus g protein coupled receptor 0.0334 0.0948 0.1328
Onchocerca volvulus 0.0334 0.0948 0.3742
Trypanosoma cruzi cysteine peptidase, putative 0.0335 0.0952 0.4826
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0034 0.0278
Echinococcus granulosus Nuclear hormone receptor HR96 0.0093 0.0229 0.032
Echinococcus granulosus acetylcholinesterase 0.0082 0.0194 0.0272
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0051 0.01 0.0507
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.014 0.0368 0.2999
Loa Loa (eye worm) CXXC zinc finger family protein 0.0089 0.0215 0.0522
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0198 0.0542 0.0542
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0034 0.01
Plasmodium vivax replication protein A1, large subunit, putative 0.0033 0.0048 0.0272
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0014
Echinococcus multilocularis aryl hydrocarbon receptor 0.005 0.0099 0.0099
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0251 0.1431
Brugia malayi Intermediate filament tail domain containing protein 0.008 0.0189 0.0522
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0192 0.0913
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0041 0.0041
Brugia malayi Serotonin receptor 0.0334 0.0948 0.2624
Loa Loa (eye worm) FAD binding domain-containing protein 0.0081 0.0191 0.0462
Trypanosoma cruzi hypothetical protein, conserved 0.017 0.0457 0.2314
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0155 0.0736
Brugia malayi putative neuropeptide receptor NPR1 0.0334 0.0948 0.2624
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0155 0.0882
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0334 0.0948 0.0948
Entamoeba histolytica cysteine protease, putative 0.0335 0.0952 0.558
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.0183 0.0498 0.2968
Schistosoma mansoni laminin gamma-3 chain 0.0048 0.0092 0.0129
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0198 0.0542 0.0759
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.017 0.0457 0.1263
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0139 0.0408
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0155 0.0783
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Schistosoma mansoni inositol monophosphatase 0.0074 0.0169 0.0237
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0133 0.1089
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0081 0.0192 0.0941
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0034 0.0278
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0334 0.0948 0.1328
Brugia malayi hypothetical protein 0.0179 0.0484 0.1339
Onchocerca volvulus Protein ultraspiracle homolog 0.0198 0.0542 0.2136
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0265 0.0742 0.3533
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0034 0.01
Echinococcus granulosus transcription factor btf3 0.0069 0.0155 0.0217
Schistosoma mansoni cpg binding protein 0.0089 0.0215 0.0302
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0012
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0063 0.0138 0.0788
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Plasmodium vivax glutathione reductase, putative 0.0037 0.006 0.0344
Giardia lamblia Cathepsin B precursor 0.0081 0.0192 0.0465
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.0183 0.0498 0.5225
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0198 0.0542 0.1315
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.008 0.0194
Schistosoma mansoni nuclear hormone receptor 0.0198 0.0542 0.0759
Brugia malayi nuclear receptor RXR 0.0093 0.0229 0.0632
Echinococcus granulosus cathepsin L cysteine protease 0.0194 0.0528 0.074
Brugia malayi bZIP transcription factor family protein 0.0085 0.0203 0.0561
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0198 0.0543 0.1501
Loa Loa (eye worm) G-protein coupled receptor 0.0334 0.0948 0.2301
Schistosoma mansoni dishevelled 0.0103 0.0258 0.0361
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0081 0.0192 0.0941
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0105 0.0262 0.0262
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0041 0.0432
Brugia malayi beta-lactamase family protein 0.0181 0.049 0.1356
Schistosoma mansoni nuclear receptor 0.0093 0.0229 0.032
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0082 0.0415
Schistosoma mansoni hypothetical protein 0.0176 0.0476 0.0667
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0082 0.0391
Mycobacterium leprae Probable lipase LipE 0.0181 0.049 0.3999
Loa Loa (eye worm) hypothetical protein 0.0037 0.006 0.0146
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0065 0.0144 0.0687
Brugia malayi Isocitrate dehydrogenase 0.0063 0.0138 0.0382
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0325 0.0922 0.1291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Loa Loa (eye worm) abnormal epIthelia family member 0.0048 0.0092 0.0222
Brugia malayi cathepsin L-like precursor 0.0223 0.0615 0.1703
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Loa Loa (eye worm) hypothetical protein 0.0082 0.0194 0.047
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0181 0.049 0.1356
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0192 0.0269
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0055 0.0575
Toxoplasma gondii cathepsin CPL 0.0335 0.0952 0.231
Schistosoma mansoni alpha-1 adrenergic receptor 0.0334 0.0948 0.1328
Schistosoma mansoni retinoic acid receptor RXR 0.0759 0.2221 0.3111
Toxoplasma gondii flavodoxin domain-containing protein 0.004 0.0069 0.0166
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0543 0.2582
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0615 0.2929
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0121 0.0311 0.3262
Echinococcus multilocularis fmrfamide receptor 0.0334 0.0948 0.0948
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0198 0.0543 0.1316
Schistosoma mansoni cell polarity protein 0.0048 0.0092 0.0129
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0166 0.0446 0.2543
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis GPCR, family 2 0.0176 0.0476 0.0476
Loa Loa (eye worm) fibroinase 0.0335 0.0952 0.231
Trypanosoma brucei unspecified product 0.0055 0.0114 0.1194
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0028 0.0032 0.0076
Trypanosoma cruzi cysteine proteinase, putative 0.0194 0.0528 0.2678
Brugia malayi conserved hypotetical protein 0.0093 0.0229 0.0632
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0019 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.005 0.0099 0.0471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0261
Entamoeba histolytica hypothetical protein 0.0065 0.0144 0.0651
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0169 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0155 0.0736
Onchocerca volvulus 0.0181 0.049 0.1931
Entamoeba histolytica hypothetical protein 0.0081 0.0192 0.0941
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.01 0.0242
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0139 0.0384
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Brugia malayi Nuclear hormone receptor E75 0.0093 0.0229 0.0632
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0169 0.0857
Echinococcus multilocularis dna polymerase eta 0.0035 0.0055 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0156 0.0218
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0335 0.0952 0.0952
Brugia malayi nuclear receptor NHR-88 0.0093 0.0229 0.0632
Onchocerca volvulus 0.005 0.0099 0.0384
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0081 0.0192 0.1094
Onchocerca volvulus 0.0065 0.0144 0.0564
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0084 0.0084
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0251 0.1271
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0138 0.0138
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0105 0.0262 0.0367
Onchocerca volvulus 0.0334 0.0948 0.3742
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0192 0.0913
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0204 0.0494
Loa Loa (eye worm) hypothetical protein 0.0048 0.0092 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0007 0.0019
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0179 0.0484 0.1174
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0334 0.0948 0.2624
Schistosoma mansoni intermediate filament proteins 0.008 0.0189 0.0265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0093 0.0229 0.0229
Brugia malayi isocitrate dehydrogenase 0.0063 0.0138 0.0382
Schistosoma mansoni RAR-like nuclear receptor 0.0198 0.0542 0.0759
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0028 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0044
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.024 0.0668 0.185
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0093 0.0229 0.0632
Entamoeba histolytica hypothetical protein 0.0289 0.0816 0.4748
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0007 0.0019
Brugia malayi hypothetical protein 0.0019 0.0007 0.0019
Leishmania major hypothetical protein, conserved 0.017 0.0457 0.4794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Loa Loa (eye worm) TYRA-2 protein 0.0334 0.0948 0.2301
Leishmania major hypothetical protein, conserved 0.0101 0.0251 0.2633
Plasmodium falciparum cysteine proteinase falcipain 3 0.0335 0.0952 0.5435
Brugia malayi cathepsin L-like cysteine proteinase 0.0081 0.0192 0.053
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0457 0.2173
Plasmodium falciparum serine repeat antigen 1 0.0081 0.0192 0.1094
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0007 0.0033
Brugia malayi Cathepsin L-like precursor 0.0335 0.0952 0.2635
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0063 0.0137 0.0534
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.012 0.0351
Giardia lamblia Cathepsin L precursor 0.0081 0.0192 0.0465
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0192 0.0913
Schistosoma mansoni ap endonuclease 0.0057 0.012 0.0168
Brugia malayi Protein kinase domain containing protein 0.0047 0.0091 0.025
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0034 0.0278
Onchocerca volvulus 0.0092 0.0225 0.0884
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0081 0.0191 0.0965
Echinococcus granulosus neuropeptides capa receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0192 0.0913
Loa Loa (eye worm) nuclear hormone receptor 0.0093 0.0229 0.0554
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0055 0.0077
Echinococcus granulosus neuropeptide receptor A26 0.0803 0.2352 0.3294
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0081 0.0192 0.0269
Mycobacterium ulcerans beta-lactamase 0.0181 0.049 0.3999
Loa Loa (eye worm) hypothetical protein 0.0112 0.0285 0.0692
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0085 0.0203 0.0203
Onchocerca volvulus 0.0028 0.0032 0.0118
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0225 0.0315
Leishmania major trypanothione reductase 0.0037 0.006 0.0632
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0335 0.0952 0.0952
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0032 0.0087
Toxoplasma gondii facilitative glucose transporter GT1 0.0019 0.0007 0.0016
Onchocerca volvulus 0.0028 0.0032 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.017 0.0457 0.2314
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.012 0.057
Giardia lamblia hypothetical protein 0.017 0.0457 0.1108
Leishmania major hypothetical protein, conserved 0.017 0.0457 0.4794
Schistosoma mansoni hypothetical protein 0.0051 0.0102 0.0143
Brugia malayi beta-lactamase 0.0181 0.049 0.1356
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.0215 0.0595
Echinococcus granulosus tumor protein p63 0.0334 0.095 0.133
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0041 0.0235
Schistosoma mansoni histamine h1 receptor 0.0334 0.0948 0.1328
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0183 0.0498 0.2522
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0156 0.0218
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0034 0.01
Echinococcus granulosus Sugar transporter ERD6 protein 0.0019 0.0007 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.01 0.014
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0133 0.0635
Brugia malayi latrophilin 2 splice variant baaae 0.038 0.1088 0.3012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0198 0.0542 0.1315
Brugia malayi neuropeptide F receptor 0.0334 0.0948 0.2624
Loa Loa (eye worm) hypothetical protein 0.0079 0.0184 0.0447
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0082 0.0194 0.0272
Echinococcus granulosus synaptic vesicle 2 protein 0.002 0.0008 0.0011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0334 0.0948 0.1328
Onchocerca volvulus 0.0223 0.0615 0.2427
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0156 0.0377
Onchocerca volvulus 0.0334 0.0948 0.3742
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0043 0.0078 0.0214
Trypanosoma cruzi MFS transporter, putative 0.0028 0.0032 0.0159
Schistosoma mansoni NADPH flavin oxidoreductase 0.0041 0.0071 0.0099
Schistosoma mansoni hypothetical protein 0.2402 0.7141 1
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0081 0.0191 0.2
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0198 0.0542 0.15
Plasmodium vivax vivapain-3 0.0194 0.0528 0.3016
Leishmania major protein kinase, putative 0.0051 0.01 0.105
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0334 0.0948 0.0948
Plasmodium vivax aspartyl protease, putative 0.0179 0.0484 0.2762
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0034 0.0172
Brugia malayi Synaptic glycoprotein SC2 0.0065 0.0144 0.0399
Brugia malayi Melatonin receptor type 1A 0.0334 0.0948 0.2624
Schistosoma mansoni tyrosine kinase 0.0079 0.0185 0.0259
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0261
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0014
Brugia malayi TAR-binding protein 0.0069 0.0156 0.043
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Brugia malayi hypothetical protein 0.0101 0.0251 0.0694
Echinococcus granulosus fmrfamide receptor 0.0334 0.0948 0.1328
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0082 0.0272
Echinococcus multilocularis cathepsin L 0.0081 0.0192 0.0192
Echinococcus multilocularis agrin 0.0019 0.0005 0.0005
Brugia malayi G-protein coupled receptor 0.0334 0.0948 0.2624
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0032 0.0077
Toxoplasma gondii cathepsin CPC2 0.0081 0.0192 0.0465
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0602 0.1751 0.425
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0041 0.0432
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0198 0.0542 0.15
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0031 0.0041 0.0235
Loa Loa (eye worm) hypothetical protein 0.0198 0.0543 0.1316
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Trypanosoma cruzi hypothetical protein, conserved 0.0181 0.049 0.2484
Schistosoma mansoni cathepsin S (C01 family) 0.0081 0.0192 0.0269
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0282 0.0793 0.6468
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0092 0.0225 0.0225
Trypanosoma cruzi hypothetical protein, conserved 0.017 0.0457 0.2314
Loa Loa (eye worm) sugar transporter 0.0019 0.0007 0.0016
Brugia malayi AKH receptor 0.0334 0.0948 0.2624
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0004
Brugia malayi fibroinase precursor 0.0081 0.0192 0.053
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0223 0.0615 0.312
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.012 0.1255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.017 0.0457 0.2173
Trypanosoma cruzi hypothetical protein, conserved 0.017 0.0457 0.2314
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus granulosus peptide allatostatin:somatostatin 0.0334 0.0948 0.1328
Schistosoma mansoni hypothetical protein 0.0176 0.0476 0.0667
Schistosoma mansoni neuropeptide f receptor 76f 0.0334 0.0948 0.1328
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Loa Loa (eye worm) hypothetical protein 0.005 0.0099 0.0239
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0043 0.0078 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Mycobacterium tuberculosis Probable dehydrogenase 0.0085 0.0203 0.0597
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0093 0.0229 0.0229
Mycobacterium tuberculosis Probable esterase LipL 0.0181 0.049 0.1439
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0034 0.01
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0133 0.1399
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0334 0.0948 0.1328
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0251 0.0608
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Schistosoma mansoni cathepsin F (C01 family) 0.0335 0.0952 0.1333
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.1223 0.3612 1
Giardia lamblia Cathepsin L-like protease 0.0081 0.0192 0.0465
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0065 0.0144 0.0202
Onchocerca volvulus 0.0334 0.0948 0.3742
Echinococcus granulosus cathepsin l1 0.0223 0.0615 0.0862
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0166 0.0446 0.0624
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Echinococcus multilocularis synaptic glycoprotein sc2 0.0065 0.0144 0.0144
Echinococcus multilocularis g protein coupled receptor 0.0334 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0191 0.0522 0.1265
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Echinococcus multilocularis serotonin receptor 0.0334 0.0948 0.0948
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0139 0.0195
Brugia malayi Calcitonin receptor-like protein seb-1 0.0557 0.1615 0.4472
Echinococcus granulosus dro:myosuppressin receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Onchocerca volvulus 0.0028 0.0032 0.0118
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0176 0.0476 0.0476
Echinococcus granulosus tar DNA binding protein 0.0069 0.0156 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Onchocerca volvulus 0.0719 0.2102 0.8304
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0198 0.0542 0.0542
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0334 0.0948 0.1328
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0074 0.0218
Loa Loa (eye worm) neuropeptide F receptor 0.0334 0.0948 0.2301
Loa Loa (eye worm) nuclear receptor NHR-67 0.0093 0.0229 0.0554
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus granulosus g protein coupled receptor 0.0334 0.0948 0.1328
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0169 0.1381
Schistosoma mansoni amine GPCR 0.0334 0.0948 0.1328
Brugia malayi Cathepsin L-like precursor 0.0223 0.0615 0.1703
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0081 0.0192 0.0269
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0084 0.0118
Schistosoma mansoni sugar transporter 0.0019 0.0007 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0074 0.0777
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0082 0.086
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0033 0.0048 0.0115
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0034 0.0278
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Giardia lamblia Synaptic glycoprotein SC2 0.0065 0.0144 0.035
Schistosoma mansoni patched 1 0.0058 0.0121 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0041 0.0432
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0081 0.0192 0.1094
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.0139 0.0705
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0002 0.0002
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0031 0.0041 0.0197
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0032 0.0118
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0065 0.0144 0.1514
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.005 0.0099 0.1036
Loa Loa (eye worm) DR-78 0.0093 0.0229 0.0554
Schistosoma mansoni microtubule-associated protein tau 0.1363 0.403 0.5644
Schistosoma mansoni aryl hydrocarbon receptor 0.0193 0.0526 0.0737
Entamoeba histolytica cysteine proteinase, putative 0.0194 0.0528 0.2995
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0194 0.0194
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0081 0.0192 0.1094
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0069 0.0194
Loa Loa (eye worm) hypothetical protein 0.0181 0.049 0.1189
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0062 0.0062
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0334 0.0948 0.0948
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0069 0.0395
Schistosoma mansoni glucose transporter 0.0019 0.0007 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0081 0.0192 0.0913
Brugia malayi RE15519p 0.0334 0.0948 0.2624
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0198 0.0542 0.0759
Echinococcus multilocularis cathepsin L cysteine protease 0.0335 0.0952 0.0952
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0198 0.0542 0.15
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.01 0.0506
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0155 0.0783
Loa Loa (eye worm) hypothetical protein 0.017 0.0457 0.1108
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0181 0.049 0.1439
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0198 0.0542 0.0759
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0289 0.0816 0.1142
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0081 0.0191 0.2
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0335 0.0952 0.231
Brugia malayi glutaminase DH11.1 0.0278 0.078 0.2159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0055 0.0261
Brugia malayi follicle stimulating hormone receptor 0.1008 0.2969 0.8219
Brugia malayi Cathepsin L-like precursor 0.0335 0.0952 0.2635
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.0183 0.0498 0.0498
Giardia lamblia Hypothetical protein 0.0072 0.0163 0.0395
Echinococcus multilocularis serotonin receptor 0.0334 0.0948 0.0948
Echinococcus multilocularis segment polarity protein dishevelled 0.0103 0.0258 0.0258
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.004 0.0111
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0019 0.0007 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0194 0.0528 0.5549
Brugia malayi N-terminal motif family protein 0.0191 0.0522 0.1443
Schistosoma mansoni neuropeptide receptor 0.0334 0.0948 0.1328
Schistosoma mansoni hypothetical protein 0.2402 0.7141 1
Brugia malayi ORL1-like opioid receptor 0.0334 0.0948 0.2624
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0099 0.0471
Mycobacterium ulcerans hypothetical protein 0.0198 0.0543 0.4427
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0334 0.0948 0.1328
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.017 0.0457 0.4794
Brugia malayi cathepsin F-like cysteine proteinase 0.0112 0.0285 0.079
Brugia malayi nuclear hormone receptor 0.0093 0.0229 0.0632
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0009 0.0044
Echinococcus granulosus neuropeptide receptor 0.0334 0.0948 0.1328
Schistosoma mansoni organic anion transporter 0.0028 0.0032 0.0044
Schistosoma mansoni cathepsin D (A01 family) 0.2074 0.616 0.8626
Echinococcus granulosus cathepsin b 0.0676 0.1972 0.2762
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Echinococcus granulosus acetylcholinesterase 0.0082 0.0194 0.0272
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0028 0.0032 0.0032
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0033 0.0048 0.0228
Leishmania major DNA polymerase eta, putative 0.0035 0.0055 0.0572
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0065 0.0091
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0034 0.0278
Brugia malayi flavodoxin family protein 0.0031 0.0041 0.0114
Trypanosoma brucei glucose transporter 1E 0.0019 0.0007 0.0071
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0133 0.0133
Giardia lamblia Sugar-proton symporter 0.0019 0.0007 0.0016
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Echinococcus multilocularis protein patched 0.0058 0.0121 0.0121
Mycobacterium ulcerans sugar transporter 0.0019 0.0007 0.0057
Brugia malayi Kringle domain containing protein 0.0018 0.0002 0.0004
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus multilocularis methionine synthase reductase 0.005 0.0098 0.0098
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0055 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Plasmodium vivax vivapain-1 0.0194 0.0528 0.3016
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0082 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0335 0.0952 0.4531
Giardia lamblia Cathepsin B precursor 0.0265 0.0742 0.1802
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0007 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Echinococcus granulosus sex peptide receptor 0.0334 0.0948 0.1328
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Schistosoma mansoni eyes absent homolog 0.0096 0.0236 0.0331
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0334 0.0948 0.1328
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Schistosoma mansoni serine/threonine protein kinase 0.005 0.01 0.014
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.4794
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0156 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0043 0.0078 0.0813
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0034 0.01
Brugia malayi sulfakinin receptor protein 0.0541 0.157 0.4346
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0198 0.0543 0.5698
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0031 0.0041 0.0431
Schistosoma mansoni inositol monophosphatase 0.0074 0.0169 0.0237
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0078 0.0813
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0048 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Echinococcus granulosus insulin receptor 0.0047 0.0091 0.0127
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.017 0.0457 0.2314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0192 0.0913
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0198 0.0542 0.15
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0282 0.0793 0.6468
Brugia malayi hypothetical protein 0.0105 0.0262 0.0725
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.0002 0.0009
Echinococcus multilocularis orexin receptor type 2 0.0334 0.0948 0.0948
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0334 0.0948 0.0948
Echinococcus granulosus intermediate filament protein 0.008 0.0189 0.0265
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0251 0.1431
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0081 0.0192 0.0269
Brugia malayi prostaglandin transporter 0.0028 0.0032 0.0087
Echinococcus multilocularis jun protein 0.0085 0.0203 0.0203
Leishmania major hypothetical protein, conserved 0.0031 0.0041 0.0431
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0066 0.0145 0.0692
Giardia lamblia Cysteine protease 0.0081 0.0192 0.0465
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0081 0.0192 0.1094
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0198 0.0542 0.0759
Echinococcus granulosus solute carrier family 22 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Plasmodium vivax vivapain-2 0.0335 0.0952 0.5435
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.005 0.0099 0.0471
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0081 0.0192 0.1094
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Schistosoma mansoni opsin-like receptor 0.0334 0.0948 0.1328
Echinococcus multilocularis solute carrier family 22 0.0019 0.0007 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trichomonas vaginalis guanylate cyclase, putative 0.005 0.0099 0.0471
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0043 0.0078 0.0813
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0031 0.0041 0.0208
Onchocerca volvulus 0.0089 0.0215 0.0844
Echinococcus granulosus follistatin 0.0019 0.0005 0.0008
Schistosoma mansoni tyrosine kinase 0.008 0.0187 0.0262
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Brugia malayi polk-prov protein 0.0037 0.0061 0.0167
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0325 0.0922 0.2552
Echinococcus granulosus solute carrier family 22 0.0019 0.0007 0.001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.008 0.0383
Echinococcus granulosus 7TM GPCR rhodopsin 0.0334 0.0948 0.1328
Trypanosoma brucei glucose transporter, putative 0.0019 0.0007 0.0071
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.1393 0.412 0.412
Echinococcus granulosus cathepsin L 0.0081 0.0192 0.0269
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0089 0.0215 0.0595
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0034 0.01
Echinococcus granulosus biogenic amine 5HT receptor 0.0334 0.0948 0.1328
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.0426 0.1226 0.3598
Brugia malayi aspartic protease BmAsp-1, identical 0.0179 0.0484 0.1339
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0139 0.1135
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0034 0.01
Echinococcus granulosus neuropeptides capa receptor 0.0334 0.0948 0.1328
Loa Loa (eye worm) G-protein coupled receptor 0.0334 0.0948 0.2301
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Schistosoma mansoni amine GPCR 0.0334 0.0948 0.1328
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Plasmodium vivax sugar transporter, putative 0.0019 0.0007 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0044
Echinococcus granulosus tm gpcr rhodopsin 0.0334 0.0948 0.1328
Brugia malayi hypothetical protein 0.0067 0.0148 0.041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0198 0.0542 0.0542
Leishmania major cysteine peptidase A (CPA) 0.0335 0.0952 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0085 0.0203 0.0597
Trichomonas vaginalis sulfite reductase, putative 0.0081 0.0191 0.0907
Schistosoma mansoni cytochrome P450 0.0028 0.0034 0.0048
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0065 0.0144 0.0651
Brugia malayi nuclear hormone receptor family member odr-7 0.0093 0.0229 0.0632
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0092 0.0225 0.0315
Echinococcus multilocularis slit 2 protein 0.0048 0.0092 0.0092
Giardia lamblia Cysteine protease 0.0081 0.0192 0.0465
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.014 0.0368 0.0515
Plasmodium vivax unspecified product 0.0194 0.0528 0.3016
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0069 0.0155 0.0376
Schistosoma mansoni amine GPCR 0.0334 0.0948 0.1328
Schistosoma mansoni slit 0.0048 0.0092 0.0129
Schistosoma mansoni hypothetical protein 0.0018 0.0002 0.0003
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.017 0.0457 0.1108
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Toxoplasma gondii preprocathepsin c precursor, putative 0.0081 0.0192 0.0465
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Onchocerca volvulus Cathepsin F homolog 0.0335 0.0952 0.3758
Loa Loa (eye worm) hypothetical protein 0.0223 0.0615 0.1493
Echinococcus multilocularis lamin 0.008 0.0189 0.0189
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0048 0.0092 0.0129
Entamoeba histolytica cysteine protease, putative 0.0081 0.0192 0.0941
Schistosoma mansoni jun-related protein 0.0069 0.0155 0.0218
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0034 0.0278
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0043 0.0078 0.0109
Echinococcus granulosus dna polymerase eta 0.0035 0.0055 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0078 0.0392
Brugia malayi laminin alpha chain 0.0048 0.0092 0.0253
Loa Loa (eye worm) hypothetical protein 0.0223 0.0615 0.1493
Onchocerca volvulus 0.0019 0.0007 0.0021
Onchocerca volvulus 0.0019 0.0007 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.005 0.01 0.0476
Schistosoma mansoni tyrosine kinase 0.008 0.0187 0.0262
Brugia malayi flavodoxin family protein 0.0081 0.0191 0.0527
Loa Loa (eye worm) hypothetical protein 0.0862 0.253 0.6142
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0025 0.0035
Schistosoma mansoni aldehyde dehydrogenase 0.0121 0.0311 0.0435
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0282 0.0793 0.2327
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0335 0.0952 0.4531
Brugia malayi Major Facilitator Superfamily protein 0.0019 0.0007 0.0019
Schistosoma mansoni biogenic amine receptor 0.0334 0.0948 0.1328
Entamoeba histolytica hypothetical protein 0.0289 0.0816 0.4748
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Schistosoma mansoni tyrosine kinase 0.0079 0.0185 0.0259
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0019 0.0007 0.001
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.0183 0.0498 0.284
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0166 0.0446 0.2489
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0334 0.0948 0.2301
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.012 0.0682
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.0426 0.1226 1
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0081 0.0191 0.1087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0082 0.0391
Entamoeba histolytica cysteine protease, putative 0.0081 0.0192 0.0941
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0014
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Trichomonas vaginalis CMGC family protein kinase 0.005 0.01 0.0476
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0289 0.0816 0.0816
Loa Loa (eye worm) glutaminase 0.0278 0.078 0.1893
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0004 0.001
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0198 0.0543 0.275
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.006 0.0344
Trichomonas vaginalis penicillin-binding protein, putative 0.0181 0.049 0.2333
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0181 0.049 0.1439
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Brugia malayi Sugar transporter family protein 0.0019 0.0007 0.0019
Echinococcus multilocularis ecdysone induced protein 78C 0.0198 0.0542 0.0542
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0198 0.0542 0.15
Echinococcus multilocularis solute carrier family 22 0.0019 0.0007 0.0007
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0156 0.0156
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.005 0.0099 0.05
Trichomonas vaginalis D-aminoacylase, putative 0.0181 0.049 0.2333
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0065 0.0144 0.0731
Leishmania major cytochrome p450-like protein 0.0028 0.0034 0.0355
Plasmodium falciparum plasmepsin IV 0.0602 0.1751 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0209 0.0293
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0019 0.0007 0.0156
Trichomonas vaginalis guanylate cyclase, putative 0.005 0.0099 0.0471
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0014
Schistosoma mansoni tyrosinase precursor 0.0089 0.0215 0.0301
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0085 0.0203 0.0597
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.01 0.01
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.006 0.0129 0.0379
Treponema pallidum flavodoxin 0.0031 0.0041 0.0247
Schistosoma mansoni cathepsin F (C01 family) 0.0223 0.0615 0.0862
Echinococcus granulosus neuropeptide Y receptor 0.0334 0.0948 0.1328
Mycobacterium ulcerans aldehyde dehydrogenase 0.0121 0.0311 0.2535
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0325 0.0922 0.1291
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.012 0.057
Brugia malayi hypothetical protein 0.0028 0.0032 0.0087
Echinococcus multilocularis beta LACTamase domain containing family member 0.0181 0.049 0.049
Onchocerca volvulus 0.0179 0.0484 0.1906
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0063 0.0138 0.0194
Onchocerca volvulus 0.0334 0.0948 0.3742
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0198 0.0542 0.15
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0139 0.0195
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0051 0.01 0.0507
Schistosoma mansoni hypothetical protein 0.0334 0.0948 0.1328
Loa Loa (eye worm) ShTK domain-containing protein 0.0089 0.0215 0.0521
Plasmodium falciparum plasmepsin VII 0.0179 0.0484 0.2762
Trypanosoma cruzi cruzipain precursor, putative 0.0335 0.0952 0.4826
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0065 0.0144 0.0687
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0078 0.0392
Loa Loa (eye worm) hypothetical protein 0.0105 0.0262 0.0636
Onchocerca volvulus 0.0019 0.0007 0.0021
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.1223 0.3612 0.8768
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.017 0.0457 0.1263
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0007 0.0071
Loa Loa (eye worm) cytochrome P450 family protein 0.0064 0.0139 0.0337
Echinococcus granulosus histone lysine methyltransferase setb 0.0092 0.0225 0.0315
Plasmodium falciparum cysteine proteinase falcipain 1 0.0194 0.0528 0.3016
Echinococcus granulosus neuropeptide FF receptor 2 0.0334 0.0948 0.1328
Brugia malayi Inositol-1 0.0074 0.0169 0.0468
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0334 0.0948 0.0948
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0176 0.0476 0.0476
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0081 0.0192 0.053
Echinococcus multilocularis sex peptide receptor 0.0334 0.0948 0.0948
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.017 0.0457 0.2314
Schistosoma mansoni memapsin-2 (A01 family) 0.0179 0.0484 0.0678
Loa Loa (eye worm) hypothetical protein 0.0028 0.0032 0.0076
Schistosoma mansoni biogenic amine receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0192 0.0913
Schistosoma mansoni hypothetical protein 0.0176 0.0476 0.0667
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0155 0.0375
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0065 0.0144 0.0687
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0325 0.0922 0.1291
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0123 0.0317 0.1508
Onchocerca volvulus 0.0334 0.0948 0.3742
Loa Loa (eye worm) hypothetical protein 0.0048 0.0092 0.0222
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Giardia lamblia Cathepsin B precursor 0.0081 0.0192 0.0465
Giardia lamblia Encystation-specific protease 0.0081 0.0192 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0198 0.0542 0.1315
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.008 0.0458
Entamoeba histolytica cysteine protease, putative 0.0081 0.0192 0.0941
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0065 0.0144 0.0202
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0325 0.0922 0.2238
Onchocerca volvulus 0.0334 0.0948 0.3742
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0602 0.1751 0.2452
Trypanosoma cruzi cysteine peptidase, putative 0.0335 0.0952 0.4826
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0063 0.0138 0.1449
Echinococcus granulosus carboxylesterase 5A 0.0082 0.0194 0.0272
Brugia malayi CXXC zinc finger family protein 0.0089 0.0215 0.0596
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0019 0.0007 0.0007
Brugia malayi hypothetical protein 0.0105 0.0262 0.0725
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0069 0.0155 0.0218
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0082 0.0082
Onchocerca volvulus 0.0334 0.0948 0.3742
Echinococcus granulosus agrin 0.0019 0.0005 0.0008
Loa Loa (eye worm) acetyltransferase 0.0149 0.0396 0.0961
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus granulosus solute carrier family 22 0.0019 0.0007 0.001
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0007 0.0034
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0325 0.0922 0.1291
Mycobacterium tuberculosis Probable lipase LipD 0.0181 0.049 0.1439
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0169 0.041
Trypanosoma cruzi hexose transporter, putative 0.0019 0.0007 0.0034
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0019 0.0007 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0055 0.0151
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0138 0.0335
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0062 0.0134 0.0521
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Echinococcus multilocularis cathepsin b 0.0676 0.1972 0.1972
Echinococcus granulosus epidermal growth factor receptor 0.008 0.0187 0.0262
Trypanosoma brucei protein kinase, putative 0.005 0.01 0.1048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0112 0.0285 0.0692
Entamoeba histolytica cysteine protease, putative 0.0081 0.0192 0.0941
Trichomonas vaginalis glutaminase, putative 0.0278 0.078 0.3713
Echinococcus granulosus single minded 2 0.0143 0.0376 0.0527
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0325 0.0922 0.0922
Plasmodium falciparum serine repeat antigen 7 0.0081 0.0192 0.1094
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.0091 0.0091
Echinococcus multilocularis neuropeptide FF receptor 2 0.0334 0.0948 0.0948
Leishmania major replication factor A, 51kDa subunit, putative 0.0033 0.0048 0.05
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.012 0.012
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.0183 0.0498 1
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0061 0.0633
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma brucei THT1 - hexose transporter, putative 0.0019 0.0007 0.0071
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0155 0.0375
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.0183 0.0498 0.1207
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0198 0.0542 0.15
Plasmodium falciparum plasmepsin V 0.0179 0.0484 0.2762
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0192 0.0913
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2606
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.017 0.0457 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0198 0.0542 0.1315
Schistosoma mansoni tyrosine kinase 0.0079 0.0185 0.0259
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0138 0.0335
Trichomonas vaginalis D-aminoacylase, putative 0.0181 0.049 0.2333
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Schistosoma mansoni transcription factor LCR-F1 0.0289 0.0816 0.1142
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.005 0.0099 0.0471
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0557 0.1615 0.4472
Loa Loa (eye worm) hypothetical protein 0.0223 0.0615 0.1493
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0051 0.01 0.0507
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Trypanosoma cruzi glucose transporter, putative 0.0019 0.0007 0.0034
Onchocerca volvulus Cathepsin L homolog 0.0335 0.0952 0.3758
Echinococcus granulosus cathepsin l cysteine peptidase 0.0335 0.0952 0.1333
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.006 0.0305
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0081 0.0192 0.0913
Brugia malayi POT family protein 0.004 0.0068 0.0187
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.017 0.0457 0.1263
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0081 0.0192 0.1094
Echinococcus granulosus neuropeptide receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Onchocerca volvulus 0.024 0.0668 0.2636
Trichomonas vaginalis myo-inositol transporter, putative 0.0019 0.0007 0.0033
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0081 0.0192 0.1094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0192 0.0269
Echinococcus granulosus orexin receptor type 2 0.0334 0.0948 0.1328
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0032 0.0118
Echinococcus multilocularis fmrfamide receptor 0.0334 0.0948 0.0948
Brugia malayi hypothetical protein 0.0093 0.0229 0.0632
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0181 0.049 0.3999
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0069 0.0168
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Brugia malayi Nuclear hormone receptor E75 0.0093 0.0229 0.0632
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0082 0.0415
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0181 0.049 0.0686
Schistosoma mansoni hypothetical protein 0.0028 0.0034 0.0048
Loa Loa (eye worm) DIX domain-containing protein 0.0027 0.0031 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0198 0.0542 0.15
Schistosoma mansoni neuropeptide F-like receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis fad synthetase, putative 0.0017 0 0.0001
Echinococcus multilocularis transfer RNA-Lys 0.0143 0.0376 0.0376
Loa Loa (eye worm) histone methyltransferase 0.0031 0.0041 0.01
Loa Loa (eye worm) hypothetical protein 0.0105 0.0262 0.0636
Echinococcus multilocularis solute carrier family 22 0.0019 0.0007 0.0007
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.0183 0.0498 0.284
Loa Loa (eye worm) hypothetical protein 0.0081 0.0192 0.0465
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Entamoeba histolytica type A flavoprotein, putative 0.0031 0.0041 0.0023
Giardia lamblia GTOR 0.0045 0.0082 0.0199
Schistosoma mansoni cpg binding protein 0.0094 0.0231 0.0323
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0334 0.0948 0.1328
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0085 0.0203 0.0284
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0396 0.0396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0198 0.0542 0.1315
Echinococcus granulosus microtubule associated protein 2 0.1363 0.403 0.5644
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0077 0.0214
Plasmodium falciparum thioredoxin reductase 0.0037 0.006 0.0344
Echinococcus multilocularis rhodopsin orphan GPCR 0.0334 0.0948 0.0948
Mycobacterium tuberculosis Probable reductase 0.0085 0.0203 0.0597
Brugia malayi cathepsin Z-like cysteine proteinase 0.0081 0.0192 0.053
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.01 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0121 0.0577
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Loa Loa (eye worm) hypothetical protein 0.0081 0.0192 0.0465
Echinococcus granulosus mitogen activated protein kinase 0.005 0.01 0.014
Plasmodium falciparum serine repeat antigen 5 0.0081 0.0192 0.1094
Plasmodium vivax serine-repeat antigen (SERA) 0.0081 0.0192 0.1094
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0334 0.0948 0.3742
Brugia malayi Common central domain of tyrosinase family protein 0.0089 0.0215 0.0595
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0081 0.0191 0.0965
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Schistosoma mansoni glucose transport protein 0.0019 0.0007 0.001
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0004 0.0042
Loa Loa (eye worm) hypothetical protein 0.0121 0.0312 0.0756
Trichomonas vaginalis CMGC family protein kinase 0.005 0.01 0.0476
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0043 0.0078 0.0188
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0034 0.01
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0093 0.0229 0.0229
Leishmania major DNA polymerase kappa, putative 0.0042 0.0074 0.0777
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0043 0.0078 0.0442
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0198 0.0542 0.0759
Loa Loa (eye worm) hypothetical protein 0.0096 0.0236 0.0573
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0031 0.0041 0.0197
Giardia lamblia Cathepsin L precursor 0.0081 0.0192 0.0465
Plasmodium falciparum serine repeat antigen 8 0.0081 0.0192 0.1094
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Onchocerca volvulus 0.0335 0.0952 0.3758
Onchocerca volvulus 0.0019 0.0007 0.0021
Entamoeba histolytica type A flavoprotein, putative 0.0031 0.0041 0.0023
Plasmodium falciparum plasmepsin X 0.0515 0.149 0.851
Schistosoma mansoni survival motor neuron protein 0.024 0.0668 0.0936
Echinococcus multilocularis epidermal growth factor receptor 0.008 0.0187 0.0187
Echinococcus granulosus cathepsin L cysteine proteinase 0.0335 0.0952 0.1333
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0192 0.053
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Trypanosoma brucei unspecified product 0.0024 0.0022 0.0227
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0081 0.0192 0.1094
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Plasmodium falciparum serine repeat antigen 3 0.0081 0.0192 0.1094
Onchocerca volvulus 0.0334 0.0948 0.3742
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.1393 0.412 1
Brugia malayi orphan nuclear receptor NR2E1 0.0093 0.0229 0.0632
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0061 0.0633
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0557 0.1615 0.3921
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.014 0.0368 0.0515
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0334 0.0948 0.0948
Onchocerca volvulus 0.0334 0.0948 0.3742
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0063 0.0138 0.0788
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0065 0.0144 0.0823
Plasmodium vivax aspartyl protease, putative 0.0515 0.149 0.851
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0012 0.0122
Loa Loa (eye worm) hypothetical protein 0.0198 0.0542 0.1315
Brugia malayi larval opioid receptor 0.0334 0.0948 0.2624
Schistosoma mansoni hypothetical protein 0.0125 0.0324 0.0454
Schistosoma mansoni neuropeptide receptor 0.0334 0.0948 0.1328
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0019 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0112 0.0285 0.0692
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2606
Giardia lamblia Hypothetical protein 0.0081 0.0192 0.0465
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0005 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0082 0.086
Loa Loa (eye worm) hypothetical protein 0.0105 0.0262 0.0636
Onchocerca volvulus 0.0019 0.0007 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Leishmania major cytochrome p450-like protein 0.0028 0.0034 0.0355
Brugia malayi Dopamine receptor 0.0334 0.0948 0.2624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0334 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0099 0.0471
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0198 0.0542 0.2136
Schistosoma mansoni DNA polymerase eta 0.0035 0.0055 0.0077
Toxoplasma gondii flavodoxin domain-containing protein 0.004 0.0069 0.0166
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.012 0.0977
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0082 0.0391
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.017 0.0457 0.2314
Echinococcus granulosus lamin 0.008 0.0189 0.0265
Onchocerca volvulus Bile acid receptor homolog 0.0862 0.253 1
Onchocerca volvulus 0.0334 0.0948 0.3742
Plasmodium vivax phosphodiesterase gamma, putative 0.017 0.0457 0.2606
Loa Loa (eye worm) latrophilin receptor protein 2 0.0176 0.0476 0.1155
Echinococcus multilocularis cysteine protease 0.0335 0.0952 0.0952
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0009 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0034 0.01
Schistosoma mansoni amine GPCR 0.0334 0.0948 0.1328
Trypanosoma cruzi hypothetical protein, conserved 0.017 0.0457 0.2314
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0034 0.0278
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.012 0.0331
Loa Loa (eye worm) hypothetical protein 0.0058 0.0121 0.0294
Loa Loa (eye worm) hypothetical protein 0.0081 0.0191 0.0462
Trypanosoma cruzi hexose transporter 0.0019 0.0007 0.0034
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0034 0.0355
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0043 0.0078 0.0392
Giardia lamblia Rab geranylgeranyltransferase 0.0043 0.0078 0.0188
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.0183 0.0498 0.5225
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.017 0.0457 0.4794
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0081 0.0192 0.1094
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.01 0.0506
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni neuropeptide receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.012 0.0682
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.014 0.0368 0.0368
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0081 0.0192 0.0913
Brugia malayi DIX domain containing protein 0.0027 0.0031 0.0086
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0198 0.0542 0.0759
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0019 0.0007 0.0071
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.001
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0034 0.0278
Schistosoma mansoni cathepsin s 0.0112 0.0285 0.04
Echinococcus granulosus geminin 0.2402 0.7141 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0055 0.0132
Schistosoma mansoni zinc finger protein 0.0093 0.0229 0.032
Mycobacterium tuberculosis Probable oxidoreductase 0.0094 0.0232 0.068
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Schistosoma mansoni amine GPCR 0.0334 0.0948 0.1328
Brugia malayi beta-NAC-like protein 0.0069 0.0155 0.0428
Brugia malayi cathepsin B-like cysteine proteinase 0.0676 0.1972 0.5459
Brugia malayi G protein-coupled receptor 0.0334 0.0948 0.2624
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.017 0.0457 0.0639
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0676 0.1972 1
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0133 0.1399
Giardia lamblia Cathepsin L precursor 0.0081 0.0192 0.0465
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0092 0.0225 0.0225
Loa Loa (eye worm) ctsf protein 0.0335 0.0952 0.231
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0034 0.0278
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.0183 0.0498 0.0697
Loa Loa (eye worm) hypothetical protein 0.0049 0.0095 0.0231
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.1393 0.412 0.5769
Schistosoma mansoni tyrosine kinase 0.0047 0.0091 0.0127
Brugia malayi cathepsin Z-like cysteine proteinase 0.0081 0.0192 0.053
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0156 0.0218
Brugia malayi nuclear receptor NHR-67 0.0093 0.0229 0.0632
Echinococcus multilocularis neuropeptide Y receptor 0.0334 0.0948 0.0948
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0034 0.01
Loa Loa (eye worm) hypothetical protein 0.017 0.0457 0.1108
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0063 0.0138 0.0406
Brugia malayi hypothetical protein 0.0121 0.0312 0.0862
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0025 0.0035
Onchocerca volvulus 0.0093 0.0229 0.0897
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.0426 0.1226 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0285 0.0692
Onchocerca volvulus 0.0019 0.0007 0.0021
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.014 0.0368 0.1863
Brugia malayi laminin-like protein K08C7.3 precursor 0.0048 0.0092 0.0253
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.006 0.0177
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0081 0.0191 0.0965
Schistosoma mansoni cytochrome P450 reductase 0.0081 0.0191 0.0267
Brugia malayi Pre-SET motif family protein 0.0632 0.1841 0.5095
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0166 0.0446 0.0624
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Echinococcus multilocularis transcription factor btf3 0.0069 0.0155 0.0155
Schistosoma mansoni growth hormone secretagogue receptor 0.0334 0.0948 0.1328
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0334 0.0948 0.1328
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0002 0.0008
Brugia malayi MH2 domain containing protein 0.0119 0.0305 0.0843
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0133 0.1399
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0081 0.0192 0.0269
Trypanosoma brucei trypanothione reductase 0.0037 0.006 0.0632
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.017 0.0457 0.1108
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0095 0.0134
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0081 0.0192 0.0465
Trichomonas vaginalis penicillin-binding protein, putative 0.0181 0.049 0.2333
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0133 0.0635
Echinococcus granulosus tachykinin peptides receptor 99D 0.0334 0.0948 0.1328
Schistosoma mansoni glutaminase 0.0278 0.078 0.1093
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0034 0.0278
Brugia malayi Cathepsin L-like precursor 0.0335 0.0952 0.2635
Loa Loa (eye worm) hypothetical protein 0.0101 0.0251 0.0608
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0043 0.0078 0.0392
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0191 0.0522 0.2055
Brugia malayi ecdysone receptor 0.0093 0.0229 0.0632
Trichomonas vaginalis conserved hypothetical protein 0.017 0.0457 0.2173
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0025 0.0035
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0055 0.0575
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.017 0.0457 0.1263
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0192 0.0913
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0192 0.0465
Loa Loa (eye worm) hypothetical protein 0.0093 0.0229 0.0554
Loa Loa (eye worm) hypothetical protein 0.0179 0.0484 0.1174
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0072 0.0163 0.0776
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.008 0.0189 0.0458
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.017 0.0457 0.2314
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0194 0.0528 0.074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0081 0.0191 0.0267
Brugia malayi hypothetical protein 0.0334 0.0948 0.2624
Schistosoma mansoni steroid hormone receptor ad4bp 0.0198 0.0542 0.0759
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0166 0.0446 0.2121
Trichomonas vaginalis D-aminoacylase, putative 0.0181 0.049 0.2333
Schistosoma mansoni cathepsin C 0.0081 0.0192 0.0269
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus granulosus methionine synthase reductase 0.005 0.0098 0.0137
Echinococcus multilocularis survival motor neuron protein 1 0.1178 0.3476 0.3476
Onchocerca volvulus 0.0335 0.0952 0.3758
Onchocerca volvulus 0.0334 0.0948 0.3742
Schistosoma mansoni ap endonuclease 0.0057 0.012 0.0168
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.012 0.029
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.017 0.0457 0.0639
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0066 0.0145 0.0691
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0093 0.0229 0.032
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0169 0.0857
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Onchocerca volvulus 0.0019 0.0007 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0192 0.0913
Schistosoma mansoni cathepsin D (A01 family) 0.2074 0.616 0.8626
Trichomonas vaginalis set domain proteins, putative 0.0719 0.2101 1
Echinococcus granulosus ecdysone induced protein 78C 0.0198 0.0542 0.0759
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0069 0.0155 0.0155
Loa Loa (eye worm) carboxylesterase 0.0082 0.0194 0.047
Brugia malayi hypothetical protein 0.0647 0.1885 0.5219
Brugia malayi Sugar transporter family protein 0.0019 0.0007 0.0019
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0034 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0181 0.049 0.1189
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0019 0.0007 0.0007
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0334 0.0948 0.1328
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0012
Plasmodium falciparum plasmepsin VIII, putative 0.0179 0.0484 0.2762
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0155 0.0714
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0021 0.0099
Trypanosoma cruzi sugar transporter, putative 0.0019 0.0007 0.0034
Trypanosoma brucei glucose transporter 2A 0.0019 0.0007 0.0071
Plasmodium vivax flavodoxin domain containing protein 0.0072 0.0163 0.093
Echinococcus multilocularis geminin 0.2402 0.7141 0.7141
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0138 0.0699
Brugia malayi hypothetical protein 0.0093 0.0229 0.0632
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0081 0.0191 0.2
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0133 0.1089
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0012
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.017 0.0457 0.0457
Giardia lamblia Cathepsin L precursor 0.0081 0.0192 0.0465
Brugia malayi nuclear receptor NHR-88 0.0198 0.0542 0.15
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Echinococcus granulosus cathepsin b 0.0676 0.1972 0.2762
Loa Loa (eye worm) hypothetical protein 0.0334 0.0948 0.2301
Brugia malayi beta-lactamase family protein 0.0181 0.049 0.1356
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0016
Schistosoma mansoni cathepsin F (C01 family) 0.0335 0.0952 0.1333
Echinococcus multilocularis neuropeptides capa receptor 0.0334 0.0948 0.0948
Onchocerca volvulus 0.0143 0.0376 0.148
Plasmodium falciparum serine repeat antigen 4 0.0081 0.0192 0.1094
Brugia malayi Cathepsin L-like cysteine proteinase 0.0223 0.0615 0.1703
Echinococcus multilocularis neuropeptide receptor 0.0334 0.0948 0.0948
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Brugia malayi Protein kinase domain containing protein 0.0018 0.0004 0.0011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0078 0.0184 0.0257
Onchocerca volvulus Putative transporter 0.0019 0.0007 0.0021
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.0324 0.0324
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0654 0.1908 0.1908
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0081 0.0191 0.0267
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0112 0.0285 0.079
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0169 0.1775
Brugia malayi Furin-like cysteine rich region family protein 0.0148 0.0392 0.1086
Toxoplasma gondii hypothetical protein 0.0043 0.0078 0.0188
Toxoplasma gondii sugar transporter ST3 0.0019 0.0007 0.0016
Echinococcus multilocularis protein dispatched 1 0.0058 0.0121 0.0121
Brugia malayi EGF-like domain containing protein 0.0048 0.0092 0.0253
Echinococcus multilocularis acetylcholinesterase 0.0082 0.0194 0.0194
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0334 0.0948 0.1328
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.017 0.0457 0.0639
Echinococcus granulosus cysteine protease 0.0194 0.0528 0.074
Echinococcus granulosus thyroid hormone receptor alpha 0.0093 0.0229 0.032
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0065 0.0144 0.0823
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0169 0.376
Trypanosoma cruzi cytochrome P450, putative 0.0064 0.0139 0.0705
Brugia malayi nuclear hormone receptor 0.0198 0.0542 0.15
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis sugar transporter, putative 0.0019 0.0007 0.0033
Trypanosoma cruzi cruzipain precursor, putative 0.0112 0.0285 0.1446
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0166 0.0446 0.2543
Plasmodium falciparum polyprenol reductase, putative 0.0065 0.0144 0.0823
Echinococcus multilocularis neuropeptides capa receptor 0.0334 0.0948 0.0948
Loa Loa (eye worm) cathepsin B 0.0265 0.0742 0.1802
Trypanosoma brucei hypothetical protein, conserved 0.017 0.0457 0.4794
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.012 0.0606
Onchocerca volvulus 0.0019 0.0007 0.0021
Onchocerca volvulus 0.008 0.0189 0.074
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0223 0.0615 0.2929
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0198 0.0542 0.15
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0058 0.0121 0.0294
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0065 0.0144 0.0202
Echinococcus granulosus synaptic glycoprotein sc2 0.0065 0.0144 0.0202
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0074 0.0777
Plasmodium falciparum phosphodiesterase delta, putative 0.017 0.0457 0.2606
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0181 0.049 0.0686
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0146 0.0429
Leishmania major basic transcription factor 3a, putative 0.0069 0.0155 0.1623
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0334 0.0948 0.1328
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0192 0.0913
Loa Loa (eye worm) tyrosinase 1 0.0089 0.0215 0.0521
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0335 0.0952 0.4531
Loa Loa (eye worm) PDE1B protein 0.017 0.0457 0.1108
Onchocerca volvulus 0.0334 0.0948 0.3742
Schistosoma mansoni tyrosinase precursor 0.0089 0.0215 0.0301
Trypanosoma cruzi cysteine peptidase, putative 0.0194 0.0528 0.2678
Echinococcus multilocularis G-protein coupled receptor, putative 0.0334 0.0948 0.0948
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0169 0.1775
Onchocerca volvulus 0.0028 0.0032 0.0118
Onchocerca volvulus Cathepsin L homolog 0.0335 0.0952 0.3758
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0334 0.0948 0.1328
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0198 0.0542 0.1315
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0181 0.049 0.1189
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.01 0.01
Entamoeba histolytica type A flavoprotein, putative 0.0031 0.0041 0.0023
Trypanosoma cruzi cysteine peptidase, putative 0.0335 0.0952 0.4826
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0325 0.0922 0.0922
Giardia lamblia DINP protein human, muc B family 0.0042 0.0074 0.018
Giardia lamblia Hexose transporter 0.0019 0.0007 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0055 0.0151
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0065 0.0144 0.0687
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.017 0.0457 0.2173
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.017 0.0457 0.0639
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0334 0.0948 0.2624
Mycobacterium ulcerans putative regulatory protein 0.0143 0.0376 0.3068
Brugia malayi hypothetical protein 0.0019 0.0007 0.0019
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1008 0.2969 0.7206
Loa Loa (eye worm) hypothetical protein 0.0089 0.0215 0.0521
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0063 0.0138 0.0138
Entamoeba histolytica cysteine protease, putative 0.0194 0.0528 0.2995
Entamoeba histolytica cysteine proteinase, putative 0.0335 0.0952 0.558
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.017 0.0457 0.1263
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0166 0.0446 0.0446
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0166 0.0446 0.2121
Brugia malayi hypothetical protein 0.0541 0.157 0.4346
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0335 0.0952 1
Onchocerca volvulus 0.0028 0.0032 0.0118
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.017 0.0457 0.4794
Echinococcus granulosus rhodopsin orphan GPCR 0.0334 0.0948 0.1328
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0033
Schistosoma mansoni lamin 0.008 0.0189 0.0265
Echinococcus granulosus tm gpcr rhodopsin 0.0334 0.0948 0.1328
Leishmania major cathepsin L-like protease 0.0335 0.0952 1
Trichomonas vaginalis glucose transporter, putative 0.0019 0.0007 0.0033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0577 0.1676 0.7978
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0334 0.0948 0.2301
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0121 0.0311 0.0912
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0064 0.0139 0.1136
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0179 0.0484 0.0678
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.008 0.0383
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0032 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0335 0.0952 0.4531
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0335 0.0952 0.231

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 18.5 nM Inhibitory concentration against acetylcholinesterase of rat cortex homogenate ChEMBL. 15689148
IC50 (binding) = 18.5 nM Inhibitory concentration against acetylcholinesterase of rat cortex homogenate ChEMBL. 15689148
IC50 (binding) = 63000 nM Inhibitory concentration against butyrylcholinesterase of rat serum ChEMBL. 15689148
IC50 (binding) = 63000 nM Inhibitory concentration against butyrylcholinesterase of rat serum ChEMBL. 15689148
Selectivity index (binding) = 3400 Selectivity index for acetylcholinesterase and butyrylcholinesterase as ratio of IC50 ChEMBL. 15689148

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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