Detailed information for compound 311612

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 695.76 | Formula: C35H38N5NaO7S
  • H donors: 1 H acceptors: 7 LogP: 6.52 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: Cc1ccc(cc1)c1c(OCCOc2ncc(cn2)c2ccco2)ncnc1[N-]S(=O)(=O)c1ccc(cc1)C(C)(C)C.CCOC(=O)C.[Na+]
  • InChi: 1S/C31H30N5O5S.C4H8O2.Na/c1-21-7-9-22(10-8-21)27-28(36-42(37,38)25-13-11-24(12-14-25)31(2,3)4)34-20-35-29(27)40-16-17-41-30-32-18-23(19-33-30)26-6-5-15-39-26;1-3-6-4(2)5;/h5-15,18-20H,16-17H2,1-4H3;3H2,1-2H3;/q-1;;+1
  • InChiKey: LWXRSVZSWDGRBN-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Endothelin receptor ET-A Starlite/ChEMBL References
Homo sapiens endothelin receptor type B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Endothelin receptor ET-A   426 aa 412 aa 20.1 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Endothelin receptor ET-A   426 aa 412 aa 21.1 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.0361 0.1099 0.1085
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0314 0.0922 0.0912
Echinococcus granulosus Immunoglobulin subtype 0.0144 0.0274 0.0274
Trichomonas vaginalis STE family protein kinase 0.0087 0.0056 0.0052
Loa Loa (eye worm) hypothetical protein 0.0101 0.0111 0.01
Schistosoma mansoni septate junction protein 0.0264 0.0731 0.0731
Schistosoma mansoni cell adhesion molecule 0.0264 0.0731 0.0731
Echinococcus multilocularis lachesin 0.0264 0.0731 0.0731
Echinococcus multilocularis casein kinase i 0.0109 0.014 0.014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0789 0.0775
Echinococcus granulosus cyclin 0.0605 0.2028 0.2028
Loa Loa (eye worm) SRC-1 0.0223 0.0573 0.0563
Trypanosoma brucei aurora B kinase 0.0145 0.0277 0.0241
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0163 0.0346 0.0346
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0094 0.0083 0.0083
Schistosoma mansoni septate junction protein 0.0144 0.0274 0.0274
Schistosoma mansoni tyrosine kinase 0.0308 0.0898 0.0898
Onchocerca volvulus 0.0305 0.0886 0.5371
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0248 0.0671 0.1783
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.004 0.004
Brugia malayi Protein kinase domain containing protein 0.01 0.0105 0.009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0085 0.0048 0.0048
Echinococcus multilocularis mitogen activated protein kinase 11 0.0158 0.0328 0.0328
Onchocerca volvulus 0.012 0.0183 0.1073
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Trichomonas vaginalis STE family protein kinase 0.0087 0.0056 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.014 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0048 0.0048
Echinococcus multilocularis tyrosine protein kinase HCK 0.0133 0.023 0.023
Onchocerca volvulus 0.0504 0.1643 1
Schistosoma mansoni protein kinase 0.0426 0.1348 0.1348
Schistosoma mansoni neuroglian 0.0279 0.0789 0.0789
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0153 0.0308 0.0301
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0469 0.1509 0.1509
Treponema pallidum NADH oxidase 0.0936 0.3286 1
Echinococcus granulosus neurogenic locus notch protein 4 0.0273 0.0764 0.0764
Entamoeba histolytica protein kinase, putative 0.0088 0.0061 0.0295
Brugia malayi Protein kinase domain containing protein 0.0215 0.0543 0.0528
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0237 0.0237
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0201 0.0489 0.0479
Trichomonas vaginalis mercuric reductase, putative 0.0936 0.3286 1
Schistosoma mansoni nephrin related 0.012 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0085 0.0048 0.0041
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0085 0.0048 0.0011
Schistosoma mansoni tyrosine kinase 0.0255 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Schistosoma mansoni basigin related 0.0144 0.0274 0.0274
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0046 0.0009
Echinococcus granulosus fibroblast growth factor receptor 4 0.024 0.064 0.064
Onchocerca volvulus 0.0504 0.1643 1
Echinococcus multilocularis neurogenic locus protein delta 0.0273 0.0764 0.0764
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0158 0.0328 0.0292
Echinococcus multilocularis c4b binding protein beta chain 0.0504 0.1643 0.1643
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0248 0.0671 0.3255
Schistosoma mansoni protein kinase C mu 0.0215 0.0545 0.0545
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0144 0.0274 0.0274
Echinococcus granulosus cGMP dependent protein kinase 1 0.0134 0.0237 0.0237
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0573 0.0573
Brugia malayi Protein kinase domain containing protein 0.0813 0.2817 0.2806
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0139 0.0256 0.0245
Schistosoma mansoni protein kinase 0.0261 0.0721 0.0721
Echinococcus granulosus tyrosine protein kinase ABL1 0.01 0.0105 0.0105
Echinococcus multilocularis protein jagged 2 0.0273 0.0764 0.0764
Echinococcus granulosus raf serine:threonine protein kinase 0.0088 0.0059 0.0059
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0144 0.0274 0.0274
Echinococcus multilocularis tyrosine protein kinase Srms 0.0186 0.0432 0.0432
Loa Loa (eye worm) TK/EGFR protein kinase 0.0598 0.2002 0.1993
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0223 0.0573 0.0573
Echinococcus multilocularis myosin iiia 0.0086 0.0051 0.0051
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0936 0.3286 1
Echinococcus granulosus CDC7 cell division cycle 7 0.0091 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0741 0.0741
Entamoeba histolytica cyclin C, putative 0.0614 0.2061 1
Echinococcus multilocularis nervana 2 0.0121 0.0185 0.0185
Brugia malayi SH2 domain containing protein 0.0396 0.1232 0.1218
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0111 0.0075
Echinococcus granulosus serine:threonine protein kinase N2 0.0293 0.0842 0.0842
Loa Loa (eye worm) hypothetical protein 0.0613 0.2057 0.2048
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0086 0.0051 0.0044
Echinococcus granulosus growth factor receptor bound protein 2 0.0092 0.0076 0.0076
Echinococcus multilocularis dual specificity 0.0139 0.0253 0.0253
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0069 0.0069
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Onchocerca volvulus 0.032 0.0944 0.5731
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Brugia malayi Variant SH3 domain containing protein 0.0094 0.0083 0.0067
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0397 0.1237 0.1237
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0214 0.0539 0.0539
Echinococcus multilocularis fat cadherin tumor suppressor 0.0273 0.0764 0.0764
Loa Loa (eye worm) gastrulation defective protein 1 0.0778 0.2684 0.2676
Onchocerca volvulus 0.012 0.0183 0.1073
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0078 0.0023 0.0023
Echinococcus multilocularis casein kinase I alpha 0.0109 0.014 0.014
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0167 0.0361 0.0361
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0936 0.3286 0.2803
Onchocerca volvulus 0.0504 0.1643 1
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0936 0.3286 1
Entamoeba histolytica protein kinase, putative 0.0145 0.0277 0.1345
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0267 0.0741 0.0706
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0129 0.0215 0.0215
Schistosoma mansoni hypothetical protein 0.0109 0.0141 0.0141
Echinococcus multilocularis casein kinase I alpha 0.0109 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0733 0.2513 0.2505
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0521 0.0521
Plasmodium falciparum serine/threonine protein kinase, putative 0.0145 0.0277 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.061 0.061
Echinococcus granulosus titin 0.012 0.0183 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0731 0.0716
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0671 0.1945
Echinococcus granulosus tyrosine protein kinase Lyn 0.0258 0.0707 0.0707
Echinococcus granulosus glutamate synthase 0.0248 0.0671 0.0671
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0162 0.0162
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0347 0.1046 0.6354
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.00000563 0.00000563
Echinococcus multilocularis neurogenic locus notch protein 0.0273 0.0764 0.0764
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.024 0.064 0.064
Onchocerca volvulus Peroxidasin homolog 0.012 0.0184 0.108
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0671 0.1945
Mycobacterium ulcerans hypothetical protein 0.0248 0.0671 0.1783
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0153 0.0308 0.0272
Echinococcus granulosus protein jagged 1 0.0273 0.0764 0.0764
Onchocerca volvulus 0.01 0.0105 0.0599
Echinococcus multilocularis tyrosine protein kinase Abl 0.0137 0.0247 0.0247
Toxoplasma gondii rhoptry neck protein RON1 0.0504 0.1643 0.1612
Schistosoma mansoni cell adhesion molecule 0.0279 0.0789 0.0789
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0214 0.0539 0.0539
Schistosoma mansoni vav2 0.0103 0.0116 0.0116
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0248 0.0671 0.1945
Echinococcus multilocularis peroxidasin 0.0264 0.0732 0.0732
Brugia malayi Cadherin domain containing protein 0.0273 0.0764 0.075
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0129 0.0215 0.0208
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0261 0.0718 0.0708
Trichomonas vaginalis STE family protein kinase 0.0136 0.0243 0.0625
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0085 0.0048 0.0011
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.014 0.0311
Echinococcus multilocularis fibroblast growth factor receptor 4 0.024 0.064 0.064
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0215 0.0204
Brugia malayi Protein kinase domain containing protein 0.0167 0.0361 0.0346
Schistosoma mansoni nephrin related 0.0144 0.0274 0.0274
Schistosoma mansoni cell adhesion molecule 0.0628 0.2115 0.2115
Loa Loa (eye worm) hypothetical protein 0.0189 0.0445 0.0434
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0605 0.2028 0.2028
Giardia lamblia Aurora kinase 0.0145 0.0277 0.0715
Onchocerca volvulus 0.0273 0.0764 0.4627
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0111 0.0074
Entamoeba histolytica protein kinase , putative 0.0145 0.0277 0.1345
Brugia malayi Protein kinase c protein 2 0.0116 0.0167 0.0151
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0199 0.0483 0.0472
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0273 0.0764 0.075
Onchocerca volvulus 0.0273 0.0764 0.4627
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0936 0.3286 0.3261
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0248 0.0671 0.1783
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0248 0.0671 0.1783
Schistosoma mansoni protein kinase 0.0191 0.0453 0.0453
Plasmodium vivax thioredoxin reductase, putative 0.2701 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0178 0.0178
Echinococcus granulosus protein jagged 2 0.0273 0.0764 0.0764
Echinococcus granulosus Glutaredoxin protein 5 0.0121 0.0185 0.0185
Trichomonas vaginalis STE family protein kinase 0.0086 0.0051 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0111 0.0075
Echinococcus granulosus protein tyrosine kinase 0.0541 0.1783 0.1783
Schistosoma mansoni serine/threonine kinase 0.0167 0.0361 0.0361
Echinococcus granulosus Immunoglobulin 0.0144 0.0274 0.0274
Echinococcus granulosus casein kinase I alpha 0.0109 0.014 0.014
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0214 0.0539 0.0539
Echinococcus multilocularis serine:threonine protein kinase N2 0.0167 0.0361 0.0361
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0731 0.0716
Trichomonas vaginalis AGC family protein kinase 0.0187 0.0437 0.1223
Loa Loa (eye worm) casein kinase 0.0176 0.0395 0.0385
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0671 0.0636
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0152 0.0306 0.0295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0241 0.0226
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0267 0.0741 0.0741
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0248 0.0671 0.0636
Echinococcus granulosus roundabout 2 0.0279 0.0789 0.0789
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0159 0.0332 0.0332
Echinococcus granulosus cGMP dependent protein kinase 0.0134 0.0237 0.0237
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0037 0.003
Echinococcus granulosus dual specificity 0.0139 0.0253 0.0253
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0094 0.0083 0.0083
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0111 0.0075
Schistosoma mansoni titin 0.012 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0248 0.0671 0.1783
Schistosoma mansoni cell adhesion molecule 0.0144 0.0274 0.0274
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0215 0.0543 0.0532
Giardia lamblia Kinase, CDC7 0.0091 0.007 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0157 0.0157
Entamoeba histolytica protein kinase 2, putative 0.0156 0.0319 0.1546
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0215 0.054
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0178 0.0427
Echinococcus multilocularis C type lectin domian containing protein 0.0504 0.1643 0.1643
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Echinococcus granulosus peroxidasin 0.0264 0.0732 0.0732
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0813 0.2817 0.2809
Echinococcus multilocularis aurora kinase A 0.0145 0.0277 0.0277
Brugia malayi EGF-like domain containing protein 0.0273 0.0764 0.075
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0186 0.0432 0.0432
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0483 0.0483
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0671 0.0671
Echinococcus multilocularis fibropellin Ia 0.0273 0.0764 0.0764
Plasmodium falciparum thioredoxin reductase 0.2701 1 1
Loa Loa (eye worm) TK protein kinase 0.0133 0.023 0.0219
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0069 0.0032
Onchocerca volvulus 0.0273 0.0764 0.4627
Schistosoma mansoni notch 0.0273 0.0764 0.0764
Entamoeba histolytica protein kinase domain containing protein 0.0139 0.0253 0.1228
Toxoplasma gondii EGF family domain-containing protein 0.0273 0.0764 0.073
Echinococcus multilocularis Immunoglobulin 0.0469 0.1509 0.1509
Schistosoma mansoni protein kinase 0.0234 0.0614 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0111 0.0111
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0214 0.0539 0.0539
Entamoeba histolytica protein kinase, putative 0.0122 0.0191 0.0926
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0789 0.0775
Echinococcus multilocularis cyclin dependent kinase 19 0.0813 0.2817 0.2817
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.1046 0.1046
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0671 0.1945
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0248 0.0671 0.0664
Entamoeba histolytica hypothetical protein 0.0122 0.0191 0.0926
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0289 0.0278
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0264 0.0731 0.4424
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0277 0.0732
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0206 0.0514
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0274
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0111 0.0075
Echinococcus granulosus tyrosine protein kinase Blk 0.0186 0.0432 0.0432
Schistosoma mansoni tyrosine kinase 0.0395 0.1229 0.1229
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0069 0.0032
Giardia lamblia Kinase, AGC AKT 0.0117 0.0172 0.0389
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0279 0.0789 0.0789
Echinococcus multilocularis tyrosine protein kinase 0.0281 0.0794 0.0794
Loa Loa (eye worm) hypothetical protein 0.0135 0.0241 0.023
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0069 0.0062
Loa Loa (eye worm) animal heme peroxidase 0.012 0.0183 0.0172
Loa Loa (eye worm) hypothetical protein 0.0144 0.0274 0.0263
Onchocerca volvulus 0.012 0.0183 0.1073
Entamoeba histolytica protein kinase, putative 0.0139 0.0253 0.1228
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0111 0.01
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0215 0.0522
Echinococcus granulosus contactin 0.0279 0.0789 0.0789
Schistosoma mansoni tyrosine kinase 0.0348 0.1051 0.1051
Brugia malayi Protein kinase domain containing protein 0.0082 0.004 0.0024
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0115 0.0164 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0164 0.0384
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0223 0.0573 0.0573
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0122 0.0191 0.018
Entamoeba histolytica protein kinase domain containing protein 0.0145 0.0277 0.1345
Loa Loa (eye worm) hypothetical protein 0.0144 0.0274 0.0263
Trypanosoma brucei NADH dehydrogenase 0.0248 0.0671 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0157 0.0157
Echinococcus multilocularis serine:threonine protein kinase 3 0.0254 0.0691 0.0691
Echinococcus multilocularis activin receptor type 0.0082 0.0037 0.0037
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0117 0.0172 0.0156
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0111 0.0111
Onchocerca volvulus Putative titin 0.012 0.0183 0.1073
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.014 0.014
Loa Loa (eye worm) AGC/AKT protein kinase 0.0296 0.0853 0.0843
Onchocerca volvulus 0.0135 0.0241 0.1429
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0191 0.0453 0.0442
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0668 0.0668
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0144 0.0274 0.0274
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0101 0.0109 0.0098
Schistosoma mansoni cell adhesion molecule 0.0135 0.0241 0.0241
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0145 0.0277 0.024
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Trypanosoma brucei protein kinase, putative 0.0129 0.0215 0.0179
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0175 0.039 0.0379
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Plasmodium falciparum casein kinase 2, alpha subunit 0.0101 0.0109 0.0072
Giardia lamblia NADH oxidase lateral transfer candidate 0.0936 0.3286 1
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0201 0.0489 0.0489
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0046 0.0034
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0157 0.015
Brugia malayi p70 ribosomal S6 kinase beta 0.0288 0.082 0.0806
Entamoeba histolytica protein kinase, putative 0.0296 0.0853 0.4139
Loa Loa (eye worm) hypothetical protein 0.0469 0.151 0.15
Schistosoma mansoni tyrosine kinase 0.0395 0.1229 0.1229
Loa Loa (eye worm) hypothetical protein 0.0084 0.0045 0.0033
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0936 0.3286 0.3261
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0388 0.1201 0.1201
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.009 0.0069 0.0058
Echinococcus granulosus hypothetical protein 0.0118 0.0174 0.0174
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0936 0.3286 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0936 0.3286 0.3281
Brugia malayi Protein kinase domain containing protein 0.0441 0.1403 0.1389
Loa Loa (eye worm) TK protein kinase 0.0281 0.0794 0.0784
Plasmodium falciparum glycogen synthase kinase 3 0.0129 0.0215 0.0179
Brugia malayi cell division control protein 2 homolog 0.0119 0.0178 0.0163
Brugia malayi serine/threonine-protein kinase plk-2 0.0267 0.0741 0.0726
Brugia malayi Protein kinase domain containing protein 0.0084 0.0046 0.003
Echinococcus granulosus defective proboscis extension response 0.0469 0.1509 0.1509
Plasmodium falciparum protein serine/threonine kinase-1 0.0153 0.0308 0.0272
Echinococcus granulosus Immunoglobulin 0.0469 0.1509 0.1509
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Echinococcus multilocularis Glutaredoxin protein 5 0.0121 0.0185 0.0185
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Brugia malayi protein kinase C II. 0.0209 0.0521 0.0506
Echinococcus granulosus calcium activated potassium channel 0.0135 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0139 0.0256 0.0245
Schistosoma mansoni tyrosine kinase 0.0223 0.0573 0.0573
Trichomonas vaginalis STE family protein kinase 0.0087 0.0056 0.0052
Schistosoma mansoni nephrin 0.0279 0.0789 0.0789
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0113 0.0157 0.012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0085 0.0048 0.0011
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0248 0.0671 0.0636
Echinococcus granulosus Immunoglobulin 0.0144 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0135 0.0241 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0529 0.0529
Brugia malayi pregnancy-associated plasma protein-A 0.0504 0.1643 0.163
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0237 0.0237
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0361 0.1099 0.1099
Echinococcus multilocularis tyrosine protein kinase shark 0.0308 0.0898 0.0898
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0248 0.0671 0.0636
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0671 0.0636
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0936 0.3286 0.3261
Onchocerca volvulus 0.0248 0.0671 0.4059
Schistosoma mansoni vam6/vps39 related 0.0109 0.0141 0.0141
Schistosoma mansoni laminin gamma-3 chain 0.0273 0.0764 0.0764
Brugia malayi Protein kinase domain containing protein 0.0163 0.0346 0.0331
Loa Loa (eye worm) Notch2 0.0273 0.0764 0.0754
Schistosoma mansoni cell polarity protein 0.0273 0.0764 0.0764
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.012 0.0183 0.0172
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0232 0.061 0.061
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0277 0.0732
Loa Loa (eye worm) hypothetical protein 0.0109 0.0141 0.013
Onchocerca volvulus Tyrosine kinase homolog 0.0472 0.152 0.9249
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Schistosoma mansoni hypothetical protein 0.012 0.0183 0.0183
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0671 0.0636
Toxoplasma gondii aurora kinase 0.0145 0.0277 0.0241
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0671 0.0636
Brugia malayi Protein kinase domain containing protein 0.01 0.0105 0.009
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0347 0.1046 0.1046
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Trichomonas vaginalis AGC family protein kinase 0.0187 0.0437 0.1223
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.022 0.0562 0.0562
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0671 0.0636
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0069 0.0334
Plasmodium falciparum apical sushi protein 0.0504 0.1643 0.1612
Brugia malayi Protein kinase domain containing protein 0.0119 0.0178 0.0163
Brugia malayi casein kinase 1, delta 0.0109 0.014 0.0125
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0274 0.0259
Echinococcus multilocularis rac serine:threonine kinase 0.0165 0.0352 0.0352
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0111 0.0111
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.004 0.0028
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0094 0.0083 0.0072
Leishmania major casein kinase II, putative 0.0101 0.0109 0.0072
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0145 0.0277 0.1345
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0094 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0234 0.0616 0.0606
Echinococcus granulosus down syndrome cell adhesion 0.012 0.0183 0.0183
Echinococcus granulosus tyrosine protein kinase Src42A 0.0141 0.0262 0.0262
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.004 0.004
Loa Loa (eye worm) TK/FAK protein kinase 0.0547 0.1806 0.1796
Brugia malayi Protein kinase domain containing protein 0.0589 0.1965 0.1953
Loa Loa (eye worm) hypothetical protein 0.0777 0.2681 0.2673
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0046 0.0009
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0671 0.0671
Echinococcus multilocularis mitogen activated protein kinase 0.0085 0.0048 0.0048
Onchocerca volvulus 0.012 0.0184 0.108
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0613 0.2057 0.2057
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0427 0.0427
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0347 0.1046 0.1046
Entamoeba histolytica protein kinase, putative 0.0074 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0135 0.0241 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.007 0.007
Brugia malayi Thioredoxin reductase 0.2701 1 1
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0249 0.0673 0.0673
Brugia malayi Peroxidasin 0.0264 0.0732 0.0717
Loa Loa (eye worm) hypothetical protein 0.0226 0.0587 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0046 0.0046
Schistosoma mansoni basigin related 0.0144 0.0274 0.0274
Entamoeba histolytica casein kinase 1, putative 0.0109 0.014 0.0681
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0308 0.0307
Echinococcus multilocularis casein kinase I delta 0.0109 0.014 0.014
Echinococcus granulosus slit 2 protein 0.0301 0.087 0.087
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.007 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0374 0.0374
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0187 0.0437 0.0426
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.012 0.0183 0.0172
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0158 0.0328 0.0321
Plasmodium vivax glycogen synthase kinase 3, putative 0.0129 0.0215 0.0178
Echinococcus granulosus neurogenic locus notch protein 0.0273 0.0764 0.0764
Brugia malayi EGF-like domain containing protein 0.0273 0.0764 0.075
Echinococcus multilocularis roundabout 2 0.0748 0.2572 0.2572
Loa Loa (eye worm) hypothetical protein 0.0264 0.0731 0.072
Echinococcus multilocularis Immunoglobulin 0.0469 0.1509 0.1509
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Trypanosoma cruzi aurora B kinase, putative 0.0145 0.0277 0.027
Schistosoma mansoni tyrosine kinase 0.0598 0.2002 0.2002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0936 0.3286 0.2803
Echinococcus multilocularis 0.012 0.0183 0.0183
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0129 0.0215 0.0179
Schistosoma mansoni titin 0.0135 0.0241 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0069 0.0069
Echinococcus multilocularis NCK adaptor protein 0.0092 0.0076 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0215 0.0543 0.155
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0237 0.0237
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0158 0.0328 0.0292
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Brugia malayi hypothetical protein 0.0144 0.0274 0.0259
Plasmodium falciparum ferrodoxin reductase-like protein 0.0248 0.0671 0.0636
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0671 0.0636
Echinococcus granulosus cyclin dependent kinase 0.0119 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0274
Schistosoma mansoni hemicentin 0.0135 0.0241 0.0241
Onchocerca volvulus 0.012 0.0183 0.1073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0111 0.0111
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0279 0.0789 0.0789
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0241 0.0226
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.0038 0.0001
Echinococcus granulosus tyrosine protein kinase HCK 0.0133 0.023 0.023
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0671 0.1945
Echinococcus granulosus protein kinase c epsilon type 0.0209 0.0521 0.0521
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Brugia malayi probable protein kinase 0.0261 0.0721 0.0706
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0684 0.0684
Onchocerca volvulus Serine\/threonine kinase homolog 0.0267 0.0741 0.4485
Echinococcus granulosus Vam6:Vps39 protein 0.0109 0.0141 0.0141
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0671 0.0636
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Echinococcus multilocularis 0.0152 0.0306 0.0306
Brugia malayi Protein kinase domain containing protein 0.0122 0.0191 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.007 0.0095
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0161 0.0161
Brugia malayi Leucine Rich Repeat family protein 0.012 0.0184 0.0168
Loa Loa (eye worm) AGC/NDR protein kinase 0.0167 0.0361 0.035
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Loa Loa (eye worm) hypothetical protein 0.045 0.144 0.143
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Loa Loa (eye worm) hypothetical protein 0.0264 0.0731 0.072
Brugia malayi Protein kinase domain containing protein 0.01 0.0105 0.009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0936 0.3286 0.3281
Schistosoma mansoni titin 0.0264 0.0731 0.0731
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0139 0.0253 0.0217
Schistosoma mansoni protein kinase 0.0109 0.014 0.014
Echinococcus granulosus tyrosine protein kinase Srms 0.0498 0.1619 0.1619
Entamoeba histolytica disulphide oxidoreductase, putative 0.0248 0.0671 0.3255
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0178 0.0171
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0085 0.0048 0.0011
Loa Loa (eye worm) hypothetical protein 0.0279 0.0789 0.0779
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0191 0.0184
Plasmodium falciparum NIMA related kinase 1 0.0136 0.0243 0.0206
Onchocerca volvulus 0.0273 0.0764 0.4627
Brugia malayi Heparan sulfate 0.0144 0.0274 0.0259
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0086 0.0051 0.0044
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0936 0.3286 0.3261
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0157 0.015
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.0141 0.0104
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0248 0.0671 0.0671
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0178 0.0864
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0671 0.0664
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.014 0.0311
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0936 0.3286 0.3286
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3281
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0248 0.0671 0.3255
Brugia malayi Sushi domain 0.0504 0.1643 0.163
Schistosoma mansoni titin 0.012 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0671 0.0671
Echinococcus multilocularis hypothetical protein 0.0099 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0144 0.0274 0.0263
Echinococcus granulosus thioredoxin glutathione reductase 0.2701 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.1508 0.1508
Brugia malayi Protein kinase domain containing protein 0.0296 0.0853 0.0839
Echinococcus multilocularis mitogen activated protein kinase 14 0.0158 0.0328 0.0328
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Toxoplasma gondii AGC kinase 0.0113 0.0157 0.012
Leishmania major protein kinase, putative 0.0101 0.0111 0.0075
Echinococcus multilocularis c src tyrosine kinase 0.0137 0.0247 0.0247
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0267 0.0741 0.073
Leishmania major protein kinase, putative 0.0153 0.0308 0.0272
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Loa Loa (eye worm) disorganized muscle protein 1 0.012 0.0183 0.0172
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0347 0.1046 0.1036
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0129 0.0215 0.0215
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0157 0.0146
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Brugia malayi Immunoglobulin domain containing protein 0.0144 0.0274 0.0259
Echinococcus multilocularis casein kinase I delta 0.0109 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0109 0.0141 0.013
Brugia malayi EGF-like domain containing protein 0.0273 0.0764 0.075
Schistosoma mansoni protein kinase 0.0087 0.0056 0.0056
Echinococcus granulosus casein kinase I alpha 0.0109 0.014 0.014
Loa Loa (eye worm) TK protein kinase 0.036 0.1097 0.1087
Entamoeba histolytica protein kinase, putative 0.0122 0.0191 0.0926
Schistosoma mansoni hypothetical protein 0.0099 0.0104 0.0104
Echinococcus multilocularis protein kinase c epsilon type 0.0209 0.0521 0.0521
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0115 0.0164 0.0164
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0388 0.1201 0.1201
Onchocerca volvulus Putative cubilin 0.0273 0.0764 0.4627
Schistosoma mansoni cell adhesion molecule 0.0144 0.0274 0.0274
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.034 0.102 0.101
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0261 0.0718 0.0718
Echinococcus granulosus twitchin 0.0624 0.2099 0.2099
Brugia malayi notch-like transmembrane receptor 0.0273 0.0764 0.075
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0308 0.0825
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.012 0.0183 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.036 0.1097 0.1083
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0144 0.0274 0.0274
Schistosoma mansoni septate junction protein 0.0264 0.0731 0.0731
Schistosoma mansoni tyrosine kinase 0.0311 0.0908 0.0908
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0248 0.0671 0.0671
Schistosoma mansoni nck2/grb4 0.009 0.0069 0.0069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0264 0.0731 0.072
Trypanosoma cruzi casein kinase, putative 0.0109 0.014 0.0134
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0109 0.014 0.0129
Loa Loa (eye worm) hypothetical protein 0.0469 0.1509 0.1499
Echinococcus multilocularis dual specificity 0.0139 0.0253 0.0253
Entamoeba histolytica protein kinase, putative 0.0133 0.023 0.1117
Loa Loa (eye worm) hypothetical protein 0.0109 0.0141 0.013
Schistosoma mansoni tyrosine kinase 0.0541 0.1783 0.1783
Entamoeba histolytica protein kinase domain containing protein 0.0101 0.0109 0.0527
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0562 0.0562
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0671 0.0671
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0936 0.3286 0.3261
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0279 0.0789 0.0779
Brugia malayi glutamate synthase 0.0248 0.0671 0.0656
Brugia malayi Protein kinase domain containing protein 0.0192 0.0456 0.0442
Onchocerca volvulus 0.01 0.0105 0.0599
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3261
Echinococcus granulosus casein kinase I delta 0.0109 0.014 0.014
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0273 0.0764 0.0764
Loa Loa (eye worm) TK/FER protein kinase 0.0396 0.1232 0.1222
Plasmodium falciparum thioredoxin reductase 0.0936 0.3286 0.3261
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0346 0.0346
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0082 0.0037 0.003
Schistosoma mansoni tyrosine kinase 0.0223 0.0573 0.0573
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Brugia malayi Prion-like- 0.012 0.0183 0.0167
Plasmodium falciparum protein kinase 5 0.0119 0.0178 0.0142
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0156 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Brugia malayi serine/threonine-protein kinase PAK 7 0.0229 0.0599 0.0584
Schistosoma mansoni titin 0.017 0.0374 0.0374
Echinococcus granulosus c4b binding protein beta chain 0.0504 0.1643 0.1643
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0347 0.1046 0.1036
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0178 0.0409
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0111 0.0075
Echinococcus multilocularis neuroglian 0.0589 0.1965 0.1965
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0158 0.0328 0.0321
Loa Loa (eye worm) hypothetical protein 0.0469 0.1509 0.1499
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0164 0.0384
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0111 0.0075
Giardia lamblia Kinase, AGC PKA 0.0113 0.0157 0.0343
Onchocerca volvulus 0.0189 0.0445 0.2677
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0589 0.1965 0.1956
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0134 0.0237 0.0201
Onchocerca volvulus 0.012 0.0183 0.1073
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0223 0.0573 0.0573
Echinococcus multilocularis roundabout 2 0.0279 0.0789 0.0789
Echinococcus granulosus titin 0.017 0.0374 0.0374
Onchocerca volvulus 0.0135 0.0241 0.1429
Echinococcus multilocularis insulin receptor 0.044 0.1398 0.1398
Schistosoma mansoni tyrosine kinase 0.0362 0.1103 0.1103
Plasmodium vivax unspecified product 0.0101 0.0109 0.0071
Leishmania major protein kinase, putative 0.0086 0.0051 0.0014
Schistosoma mansoni protein kinase 0.0145 0.0277 0.0277
Echinococcus multilocularis mitogen activated protein kinase 11 0.0158 0.0328 0.0328
Brugia malayi Muscle positioning protein 4 0.0273 0.0764 0.075
Echinococcus granulosus epidermal growth factor receptor 0.0395 0.1229 0.1229
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0731 0.0716
Brugia malayi basement membrane proteoglycan precursor 0.0144 0.0274 0.0259
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0191 0.0191
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0347 0.1046 0.1032
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Schistosoma mansoni notch 0.0273 0.0764 0.0764
Trypanosoma brucei trypanothione reductase 0.2701 1 1
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Echinococcus granulosus neurogenic locus notch protein 0.0273 0.0764 0.0764
Schistosoma mansoni protein kinase 0.0361 0.1099 0.1099
Brugia malayi Protein kinase domain containing protein 0.0187 0.0437 0.0422
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0539 0.0539
Brugia malayi RhoGAP domain containing protein 0.0094 0.0083 0.0067
Schistosoma mansoni basigin related 0.0144 0.0274 0.0274
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0215 0.1042
Onchocerca volvulus Slit protein homolog 0.0301 0.087 0.5277
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0184 0.0427 0.0427
Onchocerca volvulus 0.012 0.0183 0.1073
Loa Loa (eye worm) projectin 0.0135 0.0241 0.023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0671 0.1945
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0671 0.0664
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0936 0.3286 0.3261
Brugia malayi Myb-like DNA-binding domain containing protein 0.012 0.0183 0.0167
Loa Loa (eye worm) programmed cell death 8 0.0248 0.0671 0.066
Giardia lamblia Thioredoxin reductase 0.0248 0.0671 0.193
Onchocerca volvulus 0.0504 0.1643 1
Echinococcus multilocularis serine:threonine protein kinase 0.0114 0.0161 0.0161
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0426 0.1348 0.1348
Loa Loa (eye worm) hypothetical protein 0.0176 0.0397 0.0386
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0109 0.014 0.0129
Onchocerca volvulus 0.0109 0.014 0.0816
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0215 0.0522
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0156 0.0319 0.0312
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0119 0.0178 0.0142
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0144 0.0274 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0277 0.0277
Schistosoma mansoni growth factor receptor-bound protein 0.009 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.012 0.0183 0.0183
Echinococcus granulosus pro neuregulin 2 membrane bound 0.012 0.0183 0.0183
Echinococcus granulosus activin receptor type 0.0082 0.0037 0.0037
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0135 0.0241 0.023
Brugia malayi Variant SH3 domain containing protein 0.009 0.0069 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0238 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0813 0.2817 0.2817
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Echinococcus granulosus casein kinase ii subunit alpha 0.0101 0.0109 0.0109
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0144 0.0274 0.0274
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.0141 0.0134
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0167 0.0361 0.0361
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.024 0.064 0.064
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0936 0.3286 0.2803
Loa Loa (eye worm) CAMK protein kinase 0.017 0.0374 0.0363
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0426 0.1348 0.1348
Brugia malayi Variant SH3 domain containing protein 0.009 0.0069 0.0054
Leishmania major protein kinase, putative 0.0153 0.0308 0.0272
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.012 0.0184 0.0184
Leishmania major hypothetical protein, conserved 0.0248 0.0671 0.0636
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0441 0.1403 0.1393
Schistosoma mansoni notch 0.0273 0.0764 0.0764
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0731 0.0716
Schistosoma mansoni nephrin 0.0604 0.2023 0.2023
Mycobacterium ulcerans monoxygenase 0.0248 0.0671 0.1783
Leishmania major protein kinase, putative 0.0145 0.0277 0.0241
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0388 0.1201 0.1191
Echinococcus granulosus serine threonine protein kinase nrc 0.0156 0.0319 0.0319
Echinococcus granulosus casein kinase I gamma 0.0211 0.0529 0.0529
Brugia malayi Disorganized muscle protein 1 0.012 0.0183 0.0167
Echinococcus multilocularis titin 0.017 0.0374 0.0374
Echinococcus granulosus delta-like protein 1 0.0273 0.0764 0.0764
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Trichomonas vaginalis AGC family protein kinase 0.0113 0.0157 0.0361
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0129 0.0215 0.0179
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0114 0.0161 0.015
Echinococcus multilocularis titin 0.012 0.0183 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0253 0.0658
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0325 0.0963 0.0949
Loa Loa (eye worm) thyroid receptor interactor 0.0111 0.0149 0.0138
Brugia malayi protein-tyrosine kinase 0.0186 0.0432 0.0417
Loa Loa (eye worm) one IG domain family member 0.012 0.0183 0.0172
Loa Loa (eye worm) hypothetical protein 0.0264 0.0731 0.072
Loa Loa (eye worm) hypothetical protein 0.0087 0.0058 0.0046
Trypanosoma cruzi casein kinase, putative 0.0109 0.014 0.0134
Loa Loa (eye worm) hypothetical protein 0.0349 0.1054 0.1044
Echinococcus multilocularis nervana 2 0.0121 0.0185 0.0185
Echinococcus multilocularis mitogen activated protein kinase 14 0.0158 0.0328 0.0328
Schistosoma mansoni tyrosine kinase 0.044 0.1398 0.1398
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0964 0.3394 0.3387
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.012 0.0184 0.0184
Schistosoma mansoni protein kinase 0.0426 0.1348 0.1348
Brugia malayi EGF-like domain containing protein 0.0273 0.0764 0.075
Echinococcus multilocularis titin 0.012 0.0183 0.0183
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0248 0.0671 0.0636
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Loa Loa (eye worm) thioredoxin reductase 0.2701 1 1
Echinococcus multilocularis titin 0.012 0.0183 0.0183
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0137 0.0247 0.0247
Echinococcus granulosus aurora kinase A 0.0145 0.0277 0.0277
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0069 0.0069
Trypanosoma brucei rac serine-threonine kinase, putative 0.0296 0.0853 0.0819
Trypanosoma cruzi casein kinase, putative 0.0109 0.014 0.0134
Brugia malayi hypothetical protein 0.01 0.0105 0.009
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0144 0.0274 0.0274
Echinococcus multilocularis slit 2 protein 0.0301 0.087 0.087
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0088 0.0061 0.0295
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0135 0.0241 0.023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0241 0.0226
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0144 0.0275 0.0275
Echinococcus multilocularis Immunoglobulin 0.0144 0.0274 0.0274
Echinococcus granulosus hemicentin 1 0.0264 0.0731 0.0731
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0109 0.0141 0.0141
Echinococcus granulosus netrin receptor unc 5 0.0172 0.0381 0.0381
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0159 0.0332 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0308 0.0307
Brugia malayi Temporarily assigned gene name protein 59 0.0109 0.0141 0.0126
Echinococcus granulosus Protein kinase C brain isozyme 0.0248 0.0668 0.0668
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0671 0.0671
Echinococcus granulosus titin 0.012 0.0183 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0275 0.026
Loa Loa (eye worm) sex muscle abnormal protein 5 0.009 0.0069 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0671 0.0664
Loa Loa (eye worm) cyclin domain-containing protein 0.0605 0.2028 0.2019
Entamoeba histolytica protein kinase, putative 0.0084 0.0046 0.0221
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0136 0.0243 0.0206
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0113 0.0157 0.012
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0178 0.0178
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0573 0.0573
Brugia malayi hypothetical protein 0.022 0.0562 0.0547
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Echinococcus multilocularis casein kinase I gamma 0.0211 0.0529 0.0529
Brugia malayi Prion-like- 0.012 0.0183 0.0167
Brugia malayi Fibronectin type III domain containing protein 0.0484 0.1567 0.1554
Echinococcus multilocularis CDC7 cell division cycle 7 0.0091 0.007 0.007
Echinococcus granulosus rho-associated protein kinase 1 0.032 0.0944 0.0944
Echinococcus multilocularis calcium activated potassium channel 0.0135 0.0238 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Schistosoma mansoni netrin receptor unc5 0.0144 0.0274 0.0274
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0279 0.0789 0.0789
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.012 0.0183 0.0172
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0249 0.0673 0.0662
Entamoeba histolytica hypothetical protein 0.0371 0.1137 0.5519
Giardia lamblia Kinase, CMGC DYRK 0.0139 0.0253 0.064
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0253 0.0658
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0156 0.0319 0.0319
Brugia malayi hypothetical protein 0.0109 0.0141 0.0126
Echinococcus granulosus protein jagged 1 0.0273 0.0764 0.0764
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0119 0.0178 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0277 0.0732
Brugia malayi map kinase activated protein kinase protein 2 0.0388 0.1201 0.1187
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0048 0.0041
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Echinococcus multilocularis down syndrome cell adhesion 0.012 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.018 0.0412 0.0401
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0223 0.0573 0.0573
Echinococcus granulosus serine:threonine protein kinase 3 0.0254 0.0691 0.0691
Onchocerca volvulus Serine\/threonine kinase homolog 0.0163 0.0346 0.2074
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0111 0.0074
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0671 0.0636
Echinococcus granulosus NCK adaptor protein 0.009 0.0069 0.0069
Leishmania major protein kinase A catalytic subunit isoform 2 0.0113 0.0157 0.012
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0139 0.0253 0.0217
Giardia lamblia Kinase, CK1 Casein kinase 0.0109 0.014 0.0293
Loa Loa (eye worm) camk/dcamkl protein kinase 0.015 0.0297 0.0286
Echinococcus multilocularis 0.0118 0.0174 0.0174
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0156 0.0319 0.0283
Brugia malayi Protein kinase domain containing protein 0.0547 0.1806 0.1793
Brugia malayi EGF-like domain containing protein 0.0273 0.0764 0.075
Onchocerca volvulus 0.0135 0.0241 0.1432
Schistosoma mansoni rap gtpase-activating protein 0.0109 0.0141 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0253 0.0253
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0157 0.015
Echinococcus granulosus serine:threonine protein kinase N2 0.0127 0.0207 0.0207
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.009 0.0069 0.0069
Onchocerca volvulus 0.0504 0.1643 1
Brugia malayi Immunoglobulin domain containing protein 0.0144 0.0274 0.0259
Plasmodium falciparum cGMP-dependent protein kinase 0.0134 0.0237 0.0201
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0144 0.0274 0.0274
Echinococcus granulosus tyrosine protein kinase 0.0281 0.0794 0.0794
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0139 0.0253 0.0246
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Loa Loa (eye worm) variant SH3 domain-containing protein 0.009 0.0069 0.0058
Trichomonas vaginalis AGC family protein kinase 0.0196 0.047 0.1325
Loa Loa (eye worm) hypothetical protein 0.0248 0.0671 0.066
Loa Loa (eye worm) hypothetical protein 0.0264 0.0732 0.0721
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0589 0.1965 0.1956
Echinococcus multilocularis growth factor receptor bound protein 2 0.009 0.0069 0.0069
Leishmania major protein kinase A catalytic subunit isoform 1 0.0113 0.0157 0.012
Echinococcus granulosus protein kinase c iota type 0.0289 0.0824 0.0824
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0201 0.0489 0.0475
Brugia malayi Immunoglobulin I-set domain containing protein 0.0172 0.0381 0.0366
Toxoplasma gondii NADPH-glutathione reductase 0.0936 0.3286 0.3261
Trypanosoma brucei hypothetical protein, conserved 0.0248 0.0671 0.0636
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0248 0.0671 0.0671
Echinococcus granulosus neurogenic locus protein delta 0.0273 0.0764 0.0764
Echinococcus granulosus casein kinase i 0.0109 0.014 0.014
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0573 0.0573
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.012 0.0183 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0237 0.0237
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0936 0.3286 1
Loa Loa (eye worm) hypothetical protein 0.0264 0.0731 0.072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0241 0.0226
Echinococcus granulosus tyrosine protein kinase otk 0.0264 0.0731 0.0731
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0289 0.0274
Plasmodium falciparum glutathione reductase 0.0936 0.3286 0.3261
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0069 0.0062
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0111 0.0111
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.00000563 0.00000563
Brugia malayi Animal haem peroxidase family protein 0.012 0.0183 0.0167
Mycobacterium ulcerans ferredoxin reductase 0.0248 0.0671 0.1783
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0253 0.0658
Toxoplasma gondii AGC kinase 0.0113 0.0157 0.012
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0274
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0153 0.0308 0.0272
Brugia malayi Protein kinase domain containing protein 0.0091 0.007 0.0055
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0248 0.0671 0.1783
Brugia malayi Furin-like cysteine rich region family protein 0.0598 0.2002 0.199
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.0332 0.0317
Loa Loa (eye worm) TK/ROR protein kinase 0.0167 0.036 0.0349
Loa Loa (eye worm) AUR protein kinase 0.0145 0.0277 0.0266
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0122 0.0191 0.0155
Brugia malayi P38 map kinase family protein 2 0.0158 0.0328 0.0313
Brugia malayi Protein kinase domain containing protein 0.0199 0.0483 0.0468
Trichomonas vaginalis CK1 family protein kinase 0.0109 0.014 0.0311
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0936 0.3286 0.3286
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0316 0.0316
Schistosoma mansoni titin 0.012 0.0183 0.0183
Entamoeba histolytica protein kinase domain containing protein 0.0201 0.0489 0.2375
Brugia malayi Protein kinase domain containing protein 0.0347 0.1046 0.1032
Entamoeba histolytica SH2-protein kinase domain containing protein 0.01 0.0105 0.0509
Echinococcus granulosus titin 0.017 0.0374 0.0374
Echinococcus multilocularis hemicentin 1 0.0264 0.0731 0.0731
Loa Loa (eye worm) hypothetical protein 0.0203 0.0499 0.0488
Echinococcus granulosus cyclin dependent kinase 5 0.0119 0.0178 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Entamoeba histolytica casein kinase, putative 0.0109 0.014 0.0681
Schistosoma mansoni protein kinase 0.0234 0.0614 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0489 0.0489
Loa Loa (eye worm) hypothetical protein 0.009 0.0069 0.0058
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0046 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3281
Onchocerca volvulus 0.0504 0.1643 1
Loa Loa (eye worm) AGC/PKG protein kinase 0.0134 0.0237 0.0226
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0395 0.1229 0.1229
Schistosoma mansoni kinase 0.0285 0.0809 0.0809
Trypanosoma cruzi trypanothione reductase, putative 0.0936 0.3286 0.3281
Entamoeba histolytica PH domain containing protein kinase, putative 0.0165 0.0352 0.1707
Loa Loa (eye worm) hypothetical protein 0.008 0.0029 0.0017
Schistosoma mansoni tyrosine kinase 0.0348 0.1051 0.1051
Onchocerca volvulus 0.0504 0.1643 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0573 0.0573
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0069 0.0069
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.012 0.0183 0.0183
Schistosoma mansoni peroxidasin 0.0144 0.0275 0.0275
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0936 0.3286 0.3261
Plasmodium vivax serine/threonine kinase-1, putative 0.0153 0.0308 0.0271
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0136 0.0243 0.0206
Entamoeba histolytica protein kinase, putative 0.0087 0.0056 0.0273
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0129 0.0215 0.0215
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0248 0.0671 0.0656
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0936 0.3286 1
Brugia malayi Protein kinase domain containing protein 0.0278 0.0782 0.0768
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0059 0.0059
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0111 0.0075
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Echinococcus multilocularis casein kinase ii subunit alpha 0.0101 0.0109 0.0109
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.017 0.0374 0.0363
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0184 0.0427 0.0416
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0605 0.2028 0.2028
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0264 0.0731 0.0731
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0069 0.0032
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0936 0.3286 0.3286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3281
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0126 0.0205 0.0169
Plasmodium vivax glutathione reductase, putative 0.2701 1 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0671 0.0664
Brugia malayi Immunoglobulin I-set domain containing protein 0.0484 0.1567 0.1554
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Echinococcus granulosus neuroglian 0.0589 0.1965 0.1965
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0069 0.0069
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0248 0.0671 0.1945
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0153 0.0308 0.0301
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0167 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0301 0.087 0.086
Echinococcus granulosus protein kinase 0.0152 0.0306 0.0306
Echinococcus multilocularis tyrosine kinase 0.01 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0484 0.1567 0.1557
Mycobacterium ulcerans dehydrogenase 0.0248 0.0671 0.1783
Loa Loa (eye worm) LAD-2 short isoform 0.0144 0.0274 0.0263
Trypanosoma brucei casein kinase I, isoform 2 0.0109 0.014 0.0104
Loa Loa (eye worm) hypothetical protein 0.0264 0.0731 0.072
Giardia lamblia Kinase, PLK 0.0267 0.0741 0.2145
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Loa Loa (eye worm) hypothetical protein 0.0144 0.0274 0.0263
Echinococcus granulosus casein kinase I delta 0.0109 0.014 0.014
Echinococcus multilocularis transfer RNA-Phe 0.0135 0.0241 0.0241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3281
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Echinococcus granulosus tyrosine kinase 0.0186 0.0432 0.0432
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Brugia malayi serine/threonine kinase 12 0.0145 0.0277 0.0262
Onchocerca volvulus 0.0504 0.1643 1
Brugia malayi SH2 domain containing protein 0.01 0.0105 0.009
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0248 0.0671 0.0671
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0486 0.1573 0.1573
Schistosoma mansoni titin 0.012 0.0183 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Echinococcus multilocularis protein kinase c iota type 0.0289 0.0824 0.0824
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0764 0.075
Onchocerca volvulus 0.012 0.0183 0.1073
Onchocerca volvulus 0.01 0.0105 0.0599
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0121 0.0185 0.0185
Echinococcus multilocularis protein tyrosine kinase 0.0541 0.1783 0.1783
Loa Loa (eye worm) AUR protein kinase 0.0145 0.0277 0.0266
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0248 0.0671 0.1783
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Onchocerca volvulus 0.018 0.0412 0.2474
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0139 0.0253 0.0217
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0936 0.3286 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0267 0.0741 0.0734
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0069 0.0053
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0486 0.1573 0.1573
Echinococcus granulosus leucine rich repeat containing protein 4 0.012 0.0183 0.0183
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0144 0.0274 0.0274
Mycobacterium ulcerans glutamate synthase subunit beta 0.0248 0.0671 0.1783
Brugia malayi Immunoglobulin domain containing protein 0.0144 0.0274 0.0259
Loa Loa (eye worm) hypothetical protein 0.0733 0.2513 0.2505
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0234 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0116 0.0168 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Schistosoma mansoni g1/s-specific cyclin C 0.1219 0.4363 0.4363
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0253 0.0658
Brugia malayi Protein kinase domain containing protein 0.01 0.0105 0.009
Brugia malayi Protein kinase domain containing protein 0.0187 0.0437 0.0422
Echinococcus granulosus fibropellin Ia 0.0273 0.0764 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0668 0.0668
Schistosoma mansoni roundabout 0.0264 0.0731 0.0731
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0109 0.0141 0.0141
Brugia malayi casein kinase I 0.0109 0.014 0.0125
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0206 0.0514
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.009 0.0069 0.0031
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0153 0.0308 0.0301
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Brugia malayi Fes/CIP4 homology domain containing protein 0.0111 0.0149 0.0134
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0671 0.0664
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0178 0.0171
Brugia malayi serine/threonine-protein kinase 6 0.0145 0.0277 0.0262
Giardia lamblia Kinase, NEK 0.0136 0.0243 0.0608
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.012 0.0183 0.0172
Onchocerca volvulus 0.017 0.0374 0.2245
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0069 0.0069
Echinococcus multilocularis expressed protein 0.0084 0.0046 0.0046
Echinococcus multilocularis protein jagged 1 0.0273 0.0764 0.0764
Brugia malayi SRC-1 0.0223 0.0573 0.0559
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0274
Leishmania major protein kinase A catalytic subunit 0.0113 0.0157 0.012
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0922 0.3235 0.3228
Giardia lamblia Kinase, CMGC CK2 0.0101 0.0109 0.0195
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0264 0.0731 0.0731
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0936 0.3286 0.3261
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0085 0.0048 0.0041
Echinococcus multilocularis 0.017 0.0371 0.0371
Echinococcus multilocularis cyclin dependent kinase 1 0.0119 0.0178 0.0178
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.012 0.0183 0.0183
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0086 0.0051 0.0249
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0764 0.075
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0253 0.0658
Echinococcus granulosus mitogen activated protein kinase 3 0.0085 0.0048 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0144 0.0274 0.0274
Echinococcus granulosus cyclin dependent kinase 19 0.0813 0.2817 0.2817
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0199 0.0482 0.0482
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0159 0.0332 0.0332
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Echinococcus multilocularis neural cadherin 0.0273 0.0764 0.0764
Brugia malayi kettin 0.012 0.0183 0.0167
Loa Loa (eye worm) TK/ABL protein kinase 0.01 0.0105 0.0094
Schistosoma mansoni glutamate synthase 0.0248 0.0671 0.0671
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Echinococcus granulosus dual specificity 0.0139 0.0253 0.0253
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0232 0.061 0.061
Trypanosoma cruzi cdc2-related kinase 3 0.0119 0.0178 0.0171
Schistosoma mansoni hypothetical protein 0.0099 0.0104 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0718 0.0718
Brugia malayi Immunoglobulin I-set domain containing protein 0.0964 0.3394 0.3384
Brugia malayi Tyrosine-protein kinase abl-1 0.0137 0.0247 0.0231
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0215 0.0204
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0139 0.0253 0.0238
Loa Loa (eye worm) hypothetical protein 0.0302 0.0876 0.0866
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0113 0.0157 0.012
Echinococcus multilocularis death associated protein kinase 1 0.0831 0.2888 0.2888
Entamoeba histolytica protein kinase, putative 0.0296 0.0853 0.4139
Echinococcus granulosus tyrosine protein kinase Src42A 0.0223 0.0573 0.0573
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0048 0.0026
Schistosoma mansoni adapter molecule crk 0.009 0.0069 0.0069
Giardia lamblia Glutamate synthase 0.0248 0.0671 0.193
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0046 0.0009
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0209 0.0521 0.051
Echinococcus granulosus c src tyrosine kinase 0.0137 0.0247 0.0247
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0191 0.0184
Schistosoma mansoni slit 0.0273 0.0765 0.0765
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0111 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.004 0.0039
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0199 0.0482 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0238 0.0238
Brugia malayi EGF-like domain containing protein 0.0301 0.087 0.0856
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0361 0.1099 0.1089
Leishmania major hypothetical protein, conserved 0.0248 0.0671 0.0636
Schistosoma mansoni hypothetical protein 0.0135 0.0241 0.0241
Schistosoma mansoni netrin receptor unc5 0.0172 0.0381 0.0381
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0248 0.0671 0.0671
Trichomonas vaginalis apoptosis inducing factor, putative 0.0248 0.0671 0.1945
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0936 0.3286 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3261
Brugia malayi Protein kinase domain containing protein 0.0114 0.0161 0.0145
Echinococcus granulosus epidermal growth factor receptor 0.0598 0.2002 0.2002
Echinococcus multilocularis tyrosine protein kinase Blk 0.0186 0.0432 0.0432
Entamoeba histolytica cell division protein kinase 2, putative 0.0119 0.0178 0.0864
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0085 0.0048 0.0037
Onchocerca volvulus Peroxidasin homolog 0.012 0.0183 0.1073
Entamoeba histolytica thioredoxin reductase, putative 0.0248 0.0671 0.3255
Brugia malayi C1-like domain containing protein 0.0215 0.0545 0.053
Onchocerca volvulus 0.0129 0.0215 0.127
Schistosoma mansoni hypothetical protein 0.012 0.0183 0.0183
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0248 0.0671 0.1783
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0153 0.0308 0.0297
Brugia malayi Protein kinase domain containing protein 0.0211 0.0529 0.0514
Trichomonas vaginalis CMGC family protein kinase 0.0139 0.0253 0.0658
Echinococcus multilocularis cyclin 0.0605 0.2028 0.2028
Trichomonas vaginalis AGC family protein kinase 0.0167 0.0361 0.0989
Schistosoma mansoni cell adhesion molecule 0.0135 0.0241 0.0241
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.007 0.0095
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0995 0.3512 0.3512
Brugia malayi protein kinase C3,putative 0.0157 0.0323 0.0307
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0361 0.0361
Brugia malayi Protein kinase domain 0.0087 0.0056 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3281
Loa Loa (eye worm) hypothetical protein 0.0349 0.1054 0.1044
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0215 0.054
Schistosoma mansoni growth factor receptor-bound protein 0.0092 0.0076 0.0076
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0248 0.0668 0.0668
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0936 0.3286 0.3261
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0145 0.0277 0.0277
Echinococcus multilocularis epidermal growth factor receptor 0.0395 0.1229 0.1229
Echinococcus granulosus insulin growth factor binding 0.012 0.0183 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0178 0.0427
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0158 0.0328 0.0317
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0111 0.0074
Echinococcus granulosus roundabout 2 0.0279 0.0789 0.0789
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0936 0.3286 0.3276
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0249 0.0673 0.0673
Schistosoma mansoni protein kinase 0.0087 0.0056 0.0056
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0153 0.0308 0.0272
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0264 0.0731 0.072
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0687 0.2341 0.2329
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0078 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0144 0.0274 0.0263
Onchocerca volvulus 0.0074 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Echinococcus multilocularis Immunoglobulin 0.0144 0.0274 0.0274
Loa Loa (eye worm) hypothetical protein 0.0087 0.0058 0.0046
Onchocerca volvulus Neurogenic locus notch homolog 0.0273 0.0764 0.4627
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Echinococcus multilocularis neurogenic locus notch protein 4 0.0273 0.0764 0.0764
Loa Loa (eye worm) TK/INSR protein kinase 0.044 0.1398 0.1388
Loa Loa (eye worm) hypothetical protein 0.01 0.0105 0.0094
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0936 0.3286 0.3261
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0109 0.0141 0.0141
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0396 0.1232 0.1232
Brugia malayi Doublecortin family protein 0.015 0.0297 0.0282
Echinococcus multilocularis casein kinase I alpha 0.0109 0.014 0.014
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0167 0.036 0.036
Echinococcus granulosus nephrin 0.0135 0.0241 0.0241
Brugia malayi hypothetical protein 0.0484 0.1567 0.1554
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.004 0.0024
Giardia lamblia Kinase, STE STE20 0.0086 0.0051 0.0018
Brugia malayi GCC2 and GCC3 family protein 0.0777 0.2681 0.2669
Echinococcus granulosus serine:threonine protein kinase 0.0114 0.0161 0.0161
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0087 0.0056 0.0056
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.004 0.0028
Loa Loa (eye worm) hypothetical protein 0.0099 0.0104 0.0093
Schistosoma mansoni glutamate synthase 0.0248 0.0671 0.0671
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.019 0.0921
Loa Loa (eye worm) TK/ALK protein kinase 0.0278 0.0782 0.0771
Onchocerca volvulus 0.01 0.0105 0.0599
Echinococcus multilocularis cyclin dependent kinase 5 0.0119 0.0178 0.0178
Echinococcus multilocularis cyclin dependent kinase 0.0119 0.0178 0.0178
Brugia malayi serine/threonine protein kinase 6 0.0145 0.0277 0.0262
Entamoeba histolytica protein kinase domain containing protein 0.0082 0.0037 0.0179
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Schistosoma mansoni notch 0.0273 0.0764 0.0764
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0163 0.0346 0.0346
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0687 0.2341 0.2329
Schistosoma mansoni notch 0.0273 0.0764 0.0764
Brugia malayi EGF-like domain containing protein 0.0273 0.0764 0.075
Trypanosoma brucei Casein kinase II 0.0101 0.0109 0.0072
Schistosoma mansoni cell adhesion molecule 0.012 0.0183 0.0183
Echinococcus granulosus dual specificity 0.0139 0.0253 0.0253
Loa Loa (eye worm) TK protein kinase 0.0186 0.0432 0.0421
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0671 0.1945
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0223 0.0573 0.0573
Echinococcus granulosus expressed protein 0.0084 0.0046 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Echinococcus granulosus C type lectin domian containing protein 0.0504 0.1643 0.1643
Schistosoma mansoni slit 0.012 0.0184 0.0184
Schistosoma mansoni c4b-binding protein beta chain 0.0504 0.1643 0.1643
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0069 0.0032
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0144 0.0274 0.0274
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Plasmodium falciparum casein kinase 1 0.0109 0.014 0.0104
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0504 0.1643 0.1633
Schistosoma mansoni serine/threonine protein kinase 0.0293 0.0842 0.0842
Loa Loa (eye worm) AUR protein kinase 0.0145 0.0277 0.0266
Echinococcus multilocularis dual specificity 0.0122 0.0191 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Echinococcus granulosus cyclin dependent kinase 1 0.0119 0.0178 0.0178
Echinococcus granulosus nervana 2 0.0121 0.0185 0.0185
Schistosoma mansoni tyrosine kinase 0.0077 0.002 0.002
Leishmania major casein kinase, putative 0.0109 0.014 0.0104
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0184 0.0427 0.0412
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0069 0.0072
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0157 0.0119
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0223 0.0573 0.0573
Trypanosoma cruzi casein kinase, putative 0.0109 0.014 0.0134
Echinococcus granulosus serine/threonine protein kinase 0.0165 0.0352 0.0352
Schistosoma mansoni tyrosine kinase 0.0137 0.0247 0.0247
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0113 0.0157 0.015
Giardia lamblia Kinase, CMGC CDK 0.0119 0.0178 0.0409
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Brugia malayi Prion-like- 0.012 0.0183 0.0167
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0671 0.1945
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Toxoplasma gondii rhoptry neck protein RON9 0.0504 0.1643 0.1612
Trypanosoma brucei cdc2-related kinase 3 0.0119 0.0178 0.0142
Giardia lamblia Kinase, CMGC MAPK 0.0085 0.0048 0.0007
Echinococcus multilocularis twitchin 0.0155 0.0316 0.0316
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0671 0.1945
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0671 0.3255
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0279 0.0789 0.0789
Echinococcus granulosus protein kinase C gamma type 0.0207 0.0513 0.0513
Brugia malayi Sex muscle abnormal protein 5 0.009 0.0069 0.0054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0274 0.0259
Loa Loa (eye worm) hypothetical protein 0.056 0.1858 0.1849
Loa Loa (eye worm) TK/EPH protein kinase 0.0126 0.0206 0.0195
Plasmodium falciparum glutathione reductase 0.2701 1 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0279 0.0789 0.0789
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0046 0.0039
Giardia lamblia Kinase, NEK 0.0136 0.0243 0.0608
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0144 0.0274 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.1201 0.1201
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0469 0.1509 0.1509
Onchocerca volvulus 0.01 0.0105 0.0599
Echinococcus granulosus NDR protein kinase 0.0167 0.0361 0.0361
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0288 0.082 0.081
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0469 0.1509 0.1509
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2701 1 1
Leishmania major NADH dehydrogenase, putative 0.0248 0.0671 0.0636
Brugia malayi Prion-like- 0.0264 0.0731 0.0716
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0111 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Trichomonas vaginalis STE family protein kinase 0.0087 0.0056 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0111 0.0222
Brugia malayi Protein kinase domain containing protein 0.0589 0.1965 0.1953
Giardia lamblia Kinase, AGC PKA 0.0156 0.0319 0.0843
Echinococcus multilocularis notch 0.0273 0.0764 0.0764
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Trichomonas vaginalis AGC family protein kinase 0.0145 0.0277 0.0732
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.0789 0.0775
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0191 0.0926
Brugia malayi Protein kinase domain containing protein 0.044 0.1398 0.1385
Schistosoma mansoni protein kinase 0.0101 0.0109 0.0109
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0254 0.0691 0.068
Onchocerca volvulus 0.0091 0.007 0.0387
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Echinococcus multilocularis protein kinase shaggy 0.0129 0.0215 0.0215
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0145 0.0277 0.1345
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.0038 0.0001
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0163 0.0346 0.0335
Entamoeba histolytica p21-activated kinase 0.0096 0.009 0.0434
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0267 0.0741 0.0741
Brugia malayi intracellular kinase 0.0129 0.0215 0.02
Schistosoma mansoni notch 0.0273 0.0764 0.0764
Echinococcus multilocularis N chimaerin 0.0094 0.0083 0.0083
Echinococcus multilocularis neurogenic locus notch protein 0.0273 0.0764 0.0764
Onchocerca volvulus 0.0109 0.0141 0.0818
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0671 0.0671
Schistosoma mansoni hypothetical protein 0.0248 0.0671 0.0671
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0671 0.0664
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Brugia malayi MAP kinase sur-1 0.0085 0.0048 0.0032
Brugia malayi Serine/threonine-protein kinase SULU 0.022 0.0562 0.0547
Toxoplasma gondii casein kinase I 0.0109 0.014 0.0104
Echinococcus multilocularis hemicentin 1 0.0264 0.0731 0.0731
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0248 0.0671 0.066
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0325 0.0963 0.0953
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0248 0.0671 0.0671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0241 0.0226
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0229 0.0599 0.0588
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0087 0.0056 0.0056
Schistosoma mansoni vesicular amine transporter 0.0469 0.1509 0.1509
Toxoplasma gondii CMGC kinase, CK2 family 0.0101 0.0109 0.0072
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0167 0.0361 0.0361
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0113 0.0157 0.0141
Loa Loa (eye worm) hypothetical protein 0.0504 0.1643 0.1633
Entamoeba histolytica PH domain containing protein kinase, putative 0.0165 0.0352 0.1707
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0201 0.0489 0.0489
Onchocerca volvulus 0.0273 0.0764 0.4627
Entamoeba histolytica protein kinase, putative 0.0084 0.0046 0.0221
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Schistosoma mansoni hypothetical protein 0.0273 0.0764 0.0764
Schistosoma mansoni protein kinase 0.0152 0.0306 0.0306
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0144 0.0274 0.0274
Loa Loa (eye worm) notch protein 0.0273 0.0764 0.0754
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0731 0.0716
Brugia malayi Cam kinase protein 1 0.0101 0.0111 0.0096
Echinococcus granulosus mitogen activated protein kinase 14 0.0158 0.0328 0.0328
Echinococcus multilocularis Immunoglobulin subtype 0.0144 0.0274 0.0274
Echinococcus granulosus mitogen activated protein kinase 11 0.0158 0.0328 0.0328
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0141 0.0262 0.0262
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Schistosoma mansoni serine/threonine-protein kinase 0.0165 0.0352 0.0352
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0119 0.0178 0.0142
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0134 0.0237 0.0237
Mycobacterium ulcerans NADH dehydrogenase 0.0248 0.0671 0.1783
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Plasmodium vivax apical sushi protein, putative 0.0504 0.1643 0.1611
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Brugia malayi Protein kinase domain containing protein 0.0191 0.0453 0.0438
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0396 0.1232 0.1232
Loa Loa (eye worm) CDC7 protein kinase 0.0091 0.007 0.0059
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0094 0.0083 0.0083
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0279 0.0789 0.0789
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0234 0.0614 0.0614
Mycobacterium tuberculosis Probable oxidoreductase 0.0936 0.3286 0.2803
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0119 0.0178 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0361 0.0361
Echinococcus granulosus lachesin 0.0264 0.0731 0.0731
Echinococcus multilocularis dual specificity protein kinase clk2 0.0153 0.0308 0.0308
Giardia lamblia Kinase, CAMK CAMKL 0.009 0.0069 0.0072
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0111 0.0096
Brugia malayi Immunoglobulin I-set domain containing protein 0.012 0.0183 0.0167
Brugia malayi Protein kinase domain containing protein 0.0153 0.0308 0.0292
Entamoeba histolytica protein kinase, putative 0.0103 0.0116 0.0563
Brugia malayi Temporarily assigned gene name protein 59 0.0126 0.0205 0.019
Leishmania major hypothetical protein, conserved 0.0248 0.0671 0.0636
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0144 0.0274 0.0274
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0223 0.0573 0.0573
Entamoeba histolytica protein kinase, putative 0.0145 0.0277 0.1345
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0069 0.0058
Echinococcus multilocularis protein jagged 1 0.0273 0.0764 0.0764
Echinococcus granulosus neural cadherin 0.0273 0.0764 0.0764
Brugia malayi Hr1 repeat family protein 0.0293 0.0842 0.0828
Entamoeba histolytica protein kinase, putative 0.0082 0.004 0.0192
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0087 0.0056 0.0056
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0167 0.036 0.036
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0671 0.1945
Brugia malayi Cyclin C 0.1219 0.4363 0.4354
Echinococcus granulosus N chimaerin 0.0094 0.0083 0.0083
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Echinococcus granulosus protein jagged 2 0.0273 0.0764 0.0764
Brugia malayi hypothetical protein 0.0504 0.1643 0.163
Giardia lamblia Kinase, CMGC CLK 0.0153 0.0308 0.0808
Echinococcus multilocularis rho associated protein kinase 0.032 0.0944 0.0944
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0086 0.0051 0.0014
Loa Loa (eye worm) hypothetical protein 0.0135 0.0241 0.023
Loa Loa (eye worm) AGC/PKA protein kinase 0.0113 0.0157 0.0146
Schistosoma mansoni myosin-binding protein-related 0.0135 0.0241 0.0241
Schistosoma mansoni atypical protein kinase C 0.0295 0.0846 0.0846
Brugia malayi STE20-like kinase MST 0.0254 0.0691 0.0676
Entamoeba histolytica PH domain containing protein kinase, putative 0.0122 0.019 0.0921
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0109 0.0141 0.0141
Plasmodium vivax protein kinase Crk2 0.0119 0.0178 0.0141
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0135 0.0241 0.023
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0069 0.0032
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0156 0.0319 0.0282
Schistosoma mansoni septate junction protein 0.0273 0.0764 0.0764
Echinococcus granulosus tyrosine protein kinase Src64B 0.0223 0.0573 0.0573
Trichomonas vaginalis AGC family protein kinase 0.0296 0.0853 0.2506
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0223 0.0573 0.0573
Echinococcus granulosus casein kinase I alpha 0.0109 0.014 0.014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0241 0.0226
Entamoeba histolytica casein kinase, putative 0.0101 0.0109 0.0527
Echinococcus multilocularis netrin receptor unc 5 0.0172 0.0381 0.0381
Loa Loa (eye worm) protein kinase domain-containing protein 0.0211 0.0529 0.0518
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0121 0.0185 0.0185
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0144 0.0274 0.0274
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0248 0.0671 0.193
Entamoeba histolytica protein kinase, putative 0.0101 0.0111 0.0541
Schistosoma mansoni tyrosine kinase 0.024 0.064 0.064
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0111 0.0111
Echinococcus granulosus tyrosine kinase 0.01 0.0105 0.0105
Echinococcus granulosus nervana 2 0.0121 0.0185 0.0185
Schistosoma mansoni septate junction protein 0.0144 0.0274 0.0274
Brugia malayi Casein kinase II, alpha chain 0.0101 0.0109 0.0093
Schistosoma mansoni ephrin receptor 0.0109 0.0141 0.0141
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0139 0.0253 0.0242
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0109 0.014 0.0134
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0086 0.0051 0.0249
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0361 0.1099 0.1099
Toxoplasma gondii thioredoxin reductase 0.2701 1 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Echinococcus granulosus serine:threonine protein kinase TAO1 0.022 0.0562 0.0562
Trichomonas vaginalis AGC family protein kinase 0.0136 0.0243 0.0625
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0671 0.0636
Loa Loa (eye worm) hypothetical protein 0.0484 0.1567 0.1557
Echinococcus multilocularis thioredoxin glutathione reductase 0.2701 1 1
Schistosoma mansoni tyrosine kinase 0.0137 0.0247 0.0247
Echinococcus granulosus mitogen activated protein kinase 0.0085 0.0048 0.0048
Echinococcus granulosus titin 0.012 0.0183 0.0183
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0764 0.075
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0087 0.0056 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0936 0.3286 0.3281
Echinococcus granulosus notch 0.0273 0.0764 0.0764
Schistosoma mansoni protein kinase 0.0082 0.0037 0.0037
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0113 0.0157 0.012
Loa Loa (eye worm) hypothetical protein 0.0264 0.0731 0.072
Brugia malayi Delta serrate ligand family protein 0.0273 0.0764 0.075
Loa Loa (eye worm) glutathione reductase 0.2701 1 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0127 0.0207 0.0207
Echinococcus multilocularis epidermal growth factor receptor 0.0598 0.2002 0.2002
Loa Loa (eye worm) hypothetical protein 0.0114 0.0161 0.015
Onchocerca volvulus 0.0285 0.0811 0.4915
Trypanosoma cruzi casein kinase II, putative 0.0101 0.0109 0.0102
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0671 0.0656
Entamoeba histolytica protein kinase, putative 0.0167 0.0361 0.175
Loa Loa (eye worm) hypothetical protein 0.0589 0.1965 0.1956
Trypanosoma brucei cdc2-related kinase 1 0.0119 0.0178 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0157 0.0157
Echinococcus multilocularis expressed conserved protein 0.0134 0.0237 0.0237
Echinococcus multilocularis insulin growth factor binding 0.012 0.0183 0.0183
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0111 0.01
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0248 0.0671 0.3255
Plasmodium vivax casein kinase 1, putative 0.0109 0.014 0.0103
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0145 0.0277 0.1345
Trypanosoma cruzi casein kinase, putative 0.0109 0.014 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0178 0.0427
Entamoeba histolytica protein kinase, putative 0.0074 0.0009 0.0044
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0111 0.0075
Onchocerca volvulus 0.0504 0.1643 1
Schistosoma mansoni hypothetical protein 0.012 0.0183 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0267 0.0741 0.216
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0161 0.0373
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0184 0.0427 0.0427
Brugia malayi Kinase associated domain 1 family protein 0.0099 0.0104 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0069 0.0091
Echinococcus multilocularis dual specificity 0.0139 0.0253 0.0253
Echinococcus multilocularis serine:threonine protein kinase 38 0.0167 0.0361 0.0361
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0178 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0238 0.0238
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0152 0.0303 0.0812
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0145 0.0277 0.0277
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0048 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.2701 1 1
Echinococcus multilocularis raf serine:threonine protein kinase 0.0088 0.0059 0.0059
Echinococcus granulosus basement membrane specific heparan sulfate 0.0144 0.0274 0.0274
Echinococcus multilocularis tyrosine protein kinase ABL1 0.01 0.0105 0.0105
Echinococcus granulosus neuroglian 0.0279 0.0789 0.0789
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0455 0.1456 0.1456
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.012 0.0183 0.0183
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0671 0.0656
Echinococcus granulosus c-Jun N-terminal kinases 0.0261 0.0718 0.0718
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0087 0.0056 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.032 0.0944 0.0944
Giardia lamblia High cysteine protein 0.0273 0.0764 0.2217
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0215 0.1042
Echinococcus granulosus ephrin type A receptor 4 A 0.0109 0.0141 0.0141
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0215 0.0545 0.0534
Toxoplasma gondii selenide, water dikinase 0.0248 0.0671 0.0636
Trypanosoma cruzi polo-like protein kinase, putative 0.0267 0.0741 0.0734
Schistosoma mansoni glutamate synthase 0.0248 0.0671 0.0671
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0273 0.0764 0.4627
Loa Loa (eye worm) hypothetical protein 0.0135 0.0241 0.023
Schistosoma mansoni disulfide oxidoreductase 0.0248 0.0671 0.0671
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0119 0.0178 0.0142
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0226 0.0587 0.0587
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0274
Echinococcus multilocularis neuroglian 0.0279 0.0789 0.0789
Brugia malayi basement membrane proteoglycan 0.0144 0.0274 0.0259
Brugia malayi Protein kinase domain containing protein 0.0281 0.0794 0.078
Onchocerca volvulus 0.0504 0.1643 1
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0215 0.0545 0.053
Brugia malayi Stress-activated protein kinase jnk-1 0.0261 0.0718 0.0704
Brugia malayi protein unc-22 0.017 0.0374 0.0359
Brugia malayi Cadherin domain containing protein 0.0273 0.0764 0.075
Echinococcus granulosus dual specificity 0.0122 0.0191 0.0191
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0455 0.1456 0.1456
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0146
Echinococcus multilocularis tyrosine protein kinase otk 0.0264 0.0731 0.0731
Schistosoma mansoni hypothetical protein 0.0144 0.0274 0.0274
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0109 0.0141 0.0134
Trypanosoma brucei polo-like protein kinase 0.0267 0.0741 0.0706
Schistosoma mansoni hypothetical protein 0.012 0.0183 0.0183
Loa Loa (eye worm) TK/FER protein kinase 0.01 0.0105 0.0094
Echinococcus multilocularis roundabout 2 0.0279 0.0789 0.0789
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0111 0.0111
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0248 0.0671 0.0671
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0186 0.0432 0.0432
Schistosoma mansoni cell adhesion molecule 0.0279 0.0789 0.0789
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0135 0.0241 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0539 0.0539
Schistosoma mansoni serine/threonine kinase 0.0215 0.0543 0.0543
Loa Loa (eye worm) hypothetical protein 0.0484 0.1567 0.1557
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0671 0.1945
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0248 0.0671 0.0636
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0048 0.0026
Giardia lamblia Kinase, STE STE20 0.0087 0.0056 0.0033
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0101 0.0109 0.0071
Brugia malayi Cyclin, N-terminal domain containing protein 0.0605 0.2028 0.2015
Trypanosoma cruzi Protein kinase B 0.0165 0.0352 0.0345
Trypanosoma brucei protein kinase, putative 0.0085 0.0048 0.0011
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0087 0.0056 0.0056
Entamoeba histolytica protein kinase, putative 0.0129 0.0215 0.1042
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.0109 0.0213
Echinococcus multilocularis serine:threonine protein kinase N2 0.0293 0.0842 0.0842
Brugia malayi Protein kinase domain containing protein 0.0922 0.3235 0.3225
Onchocerca volvulus Netrin receptor homolog 0.0148 0.029 0.173
Schistosoma mansoni serine/threonine-protein kinase 0.0165 0.0352 0.0352
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.061 0.061
Brugia malayi Protein kinase domain containing protein 0.01 0.0105 0.009
Onchocerca volvulus 0.01 0.0105 0.0599
Echinococcus granulosus tyrosine protein kinase shark 0.0308 0.0898 0.0898
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0671 0.3255
Loa Loa (eye worm) cyclin C 0.1219 0.4363 0.4356
Trichomonas vaginalis glutathione reductase, putative 0.0936 0.3286 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0936 0.3286 0.3261
Schistosoma mansoni ste20-related kinase 0.0203 0.0499 0.0499
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0113 0.0157 0.0157
Echinococcus granulosus insulin receptor 0.044 0.1398 0.1398
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0153 0.0308 0.0301
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0671 0.0664
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0069 0.0032
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.022 0.0562 0.0552
Onchocerca volvulus 0.0091 0.007 0.0387
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Entamoeba histolytica serine/threonine protein kinase, putative 0.0267 0.0741 0.3594
Loa Loa (eye worm) hypothetical protein 0.0273 0.0764 0.0754
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0046 0.0008
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0144 0.0275 0.0275
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0085 0.0048 0.0041
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0248 0.0671 0.0671
Schistosoma mansoni titin 0.012 0.0183 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0673 0.0673
Brugia malayi Immunoglobulin I-set domain containing protein 0.017 0.0374 0.0359
Loa Loa (eye worm) AGC/PKN protein kinase 0.0293 0.0842 0.0832
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0163 0.0345 0.0334
Echinococcus granulosus dual specificity protein kinase clk2 0.0153 0.0308 0.0308
Schistosoma mansoni hypothetical protein 0.012 0.0183 0.0183
Echinococcus multilocularis glutamate synthase 0.0248 0.0671 0.0671
Toxoplasma gondii AGC kinase 0.0288 0.082 0.0786
Echinococcus multilocularis serine threonine protein kinase 0.0207 0.0513 0.0513
Trichomonas vaginalis CMGC family protein kinase 0.0085 0.0048 0.0026
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0122 0.0191 0.0155
Schistosoma mansoni tyrosine kinase 0.044 0.1398 0.1398
Giardia lamblia Kinase, NEK 0.0136 0.0243 0.0608
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0165 0.0352 0.0345
Echinococcus granulosus tyrosine protein kinase Fyn 0.0223 0.0573 0.0573
Plasmodium vivax ferrodoxin reductase, putative 0.0248 0.0671 0.0636
Leishmania major trypanothione reductase 0.2701 1 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0183 0.0172
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0671 0.0664
Echinococcus multilocularis neurogenic locus protein delta 0.0273 0.0764 0.0764
Schistosoma mansoni tyrosine kinase 0.0348 0.1051 0.1051
Loa Loa (eye worm) TK protein kinase 0.0343 0.103 0.102
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0397 0.1237 0.1237
Echinococcus granulosus protein kinase shaggy 0.0129 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.0118 0.0174 0.0163
Echinococcus granulosus roundabout 2 0.0748 0.2572 0.2572
Entamoeba histolytica protein kinase, putative 0.0288 0.082 0.3978
Trypanosoma cruzi cdc2-related kinase 1 0.0119 0.0178 0.0171
Onchocerca volvulus 0.0139 0.0256 0.1524
Echinococcus multilocularis ephrin type A receptor 4 A 0.0109 0.0141 0.0141
Brugia malayi Immunoglobulin I-set domain containing protein 0.0264 0.0731 0.0716
Schistosoma mansoni protein kinase 0.0426 0.1348 0.1348
Schistosoma mansoni serine/threonine protein kinase 0.0119 0.0178 0.0178
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0119 0.0178 0.0167
Echinococcus granulosus low density lipoprotein receptor ldl 0.0144 0.0274 0.0274
Brugia malayi Egg laying defective protein 4 0.0134 0.0237 0.0222
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0223 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.014 0.0259 0.0248
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0113 0.0157 0.012
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0248 0.0671 0.0636

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.48 nM In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cells ChEMBL. 11585441
IC50 (binding) = 0.48 nM In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cells ChEMBL. 11585441
IC50 (binding) = 7 nM In vitro for specific binding of [125I]-ET-1 to GHcell expressed in Endothelin B receptor ChEMBL. 11585441
IC50 (binding) = 7 nM In vitro for specific binding of [125I]-ET-1 to GHcell expressed in Endothelin B receptor ChEMBL. 11585441

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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