Detailed information for compound 311621

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 330.832 | Formula: C17H15ClN2OS
  • H donors: 2 H acceptors: 2 LogP: 4.3 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1nc2c(s1)c1c(cc2Cl)CCNC[C@@H]1c1ccccc1
  • InChi: 1S/C17H15ClN2OS/c18-13-8-11-6-7-19-9-12(10-4-2-1-3-5-10)14(11)16-15(13)20-17(21)22-16/h1-5,8,12,19H,6-7,9H2,(H,20,21)/t12-/m1/s1
  • InChiKey: MWAJWXXODKGYIP-GFCCVEGCSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0186 0.0186
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Schistosoma mansoni cell adhesion molecule 0.0697 0.2217 0.2217
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0172 0.0176 0.0142
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0246 0.0463 0.0463
Schistosoma mansoni serine/threonine kinase 0.0466 0.1317 0.1317
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0234 0.0416 0.0383
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0168 0.0159 0.0125
Leishmania major hypothetical protein, conserved 0.0248 0.0472 0.0439
Giardia lamblia Kinase, CAMK CAMKL 0.0179 0.0204 0.0093
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0814 0.2672 0.2672
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0255 0.0499 0.0499
Brugia malayi SH2 domain containing protein 0.0135 0.0033 0.0033
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0175 0.0189 0.0154
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0463 0.1402
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi Protein kinase domain containing protein 0.0314 0.0727 0.0727
Trichomonas vaginalis STE family protein kinase 0.0282 0.0602 0.1848
Leishmania major protein kinase, putative 0.0318 0.0742 0.071
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0263 0.0528 0.0528
Leishmania major casein kinase II, putative 0.0207 0.0313 0.0279
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus multilocularis mitogen activated protein kinase 14 0.0329 0.0786 0.0786
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0243 0.0453 0.0453
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0472 0.0439
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0333 0.0801 0.0801
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0416 0.0416
Trypanosoma cruzi trypanothione reductase, putative 0.0935 0.3143 0.3119
Brugia malayi protein unc-22 0.022 0.0361 0.0361
Schistosoma mansoni tyrosine kinase 0.0432 0.1187 0.1187
Brugia malayi Protein kinase domain containing protein 0.0169 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0286 0.0621 0.0621
Echinococcus multilocularis NCK adaptor protein 0.0129 0.0008 0.0008
Echinococcus granulosus roundabout 2 0.0307 0.07 0.07
Echinococcus multilocularis roundabout 2 0.0829 0.2731 0.2731
Echinococcus multilocularis mitogen activated protein kinase 11 0.0329 0.0786 0.0786
Brugia malayi Prion-like- 0.0288 0.0627 0.0627
Schistosoma mansoni protein kinase 0.0133 0.0026 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.1465 0.1465
Leishmania major protein kinase, putative 0.0175 0.0189 0.0154
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Echinococcus multilocularis protein jagged 2 0.0273 0.0567 0.0567
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0935 0.3143 0.3119
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0318 0.0742 0.0742
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0463 0.1402
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Brugia malayi cell division control protein 2 homolog 0.0246 0.0463 0.0463
Onchocerca volvulus 0.0135 0.0033 0.0055
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Echinococcus granulosus neurogenic locus protein delta 0.0273 0.0567 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.0672 0.2118 0.2118
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0248 0.0472 0.0472
Toxoplasma gondii AGC kinase 0.0234 0.0416 0.0383
Brugia malayi intracellular kinase 0.0266 0.0542 0.0542
Plasmodium vivax casein kinase 1, putative 0.0225 0.0381 0.0225
Schistosoma mansoni glutamate synthase 0.0248 0.0472 0.0472
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Entamoeba histolytica cell division protein kinase 2, putative 0.0263 0.0529 0.1696
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0896 0.2991 0.2991
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0477 0.152
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Echinococcus granulosus cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0288 0.0627 0.0627
Brugia malayi serine/threonine protein kinase 6 0.0243 0.0453 0.0453
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0361 0.0361
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0151 0.0094 0.0275
Schistosoma mansoni growth factor receptor-bound protein 0.0129 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.0135 0.0033 0.0055
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0169 0.0163 0.0163
Brugia malayi pregnancy-associated plasma protein-A 0.0504 0.1465 0.1465
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0287 0.0624 0.0624
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0324 0.0766 0.0766
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.0186 0.023 0.023
Echinococcus multilocularis neurogenic locus protein delta 0.0273 0.0567 0.0567
Echinococcus granulosus basement membrane specific heparan sulfate 0.0156 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Plasmodium falciparum calcium-dependent protein kinase 4 0.0209 0.0319 0.0285
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0253 0.049 0.0457
Schistosoma mansoni protein kinase 0.0547 0.1635 0.1635
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0699 0.2225 0.2225
Echinococcus granulosus tyrosine kinase 0.0257 0.0506 0.0506
Echinococcus granulosus protein jagged 1 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0168 0.0161 0.0161
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0935 0.3143 0.3119
Brugia malayi Protein kinase domain containing protein 0.0757 0.2452 0.2452
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0133 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.1395 0.1395
Brugia malayi kettin 0.0132 0.0021 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0477 0.152
Schistosoma mansoni rap gtpase-activating protein 0.0231 0.0404 0.0404
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Loa Loa (eye worm) programmed cell death 8 0.0248 0.0472 0.0472
Schistosoma mansoni biogenic amine (5HT) receptor 0.1209 0.4209 0.4209
Giardia lamblia Kinase, NEK 0.0282 0.0602 0.1434
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Toxoplasma gondii rhoptry neck protein RON9 0.0504 0.1465 0.1435
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1021 0.3476 0.3476
Echinococcus granulosus tyrosine protein kinase Srms 0.056 0.1685 0.1685
Trichomonas vaginalis CMGC family protein kinase 0.0266 0.0542 0.1656
Loa Loa (eye worm) hypothetical protein 0.0557 0.1673 0.1673
Onchocerca volvulus 0.0132 0.0021 0.0012
Onchocerca volvulus 0.0672 0.2118 0.7583
Schistosoma mansoni serine/threonine protein kinase 0.0985 0.3336 0.3336
Loa Loa (eye worm) hypothetical protein 0.066 0.2072 0.2072
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Echinococcus granulosus hemicentin 1 0.0288 0.0627 0.0627
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0156 0.0113 0.0113
Trypanosoma brucei hypothetical protein, conserved 0.0248 0.0472 0.0439
Brugia malayi Protein kinase domain containing protein 0.062 0.1918 0.1918
Echinococcus granulosus serine:threonine protein kinase N2 0.0268 0.0547 0.0547
Echinococcus multilocularis Immunoglobulin 0.0522 0.1538 0.1538
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0419 0.1135 0.1135
Onchocerca volvulus Tyrosine kinase homolog 0.0844 0.2787 1
Schistosoma mansoni protein kinase 0.0136 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.025 0.0479 0.0479
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Plasmodium vivax glutathione reductase, putative 0.2699 1 1
Schistosoma mansoni tyrosine kinase 0.0316 0.0734 0.0734
Echinococcus multilocularis neuroglian 0.0655 0.2052 0.2052
Schistosoma mansoni protein kinase 0.0896 0.2991 0.2991
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Entamoeba histolytica protein kinase, putative 0.0333 0.0801 0.2611
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0151 0.0094 0.0094
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0225 0.0381 0.0348
Echinococcus multilocularis cyclin dependent kinase 19 0.1188 0.4125 0.4125
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Echinococcus multilocularis neurogenic locus notch protein 0.0273 0.0567 0.0567
Echinococcus granulosus neuroglian 0.0655 0.2052 0.2052
Schistosoma mansoni nephrin related 0.0156 0.0113 0.0113
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0288 0.0627 0.0627
Echinococcus multilocularis rho associated protein kinase 0.0672 0.2118 0.2118
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0173 0.0181 0.0147
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0472 0.0439
Loa Loa (eye worm) hypothetical protein 0.0952 0.3209 0.3209
Toxoplasma gondii CMGC kinase, CK2 family 0.0207 0.0313 0.0279
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0827 0.0827
Trypanosoma cruzi casein kinase II, putative 0.0207 0.0313 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0163 0.0441
Trypanosoma brucei cdc2-related kinase 1 0.0246 0.0463 0.0429
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0234 0.0416 0.0383
Echinococcus granulosus mitogen activated protein kinase 11 0.0329 0.0786 0.0786
Brugia malayi Protein kinase domain containing protein 0.0339 0.0826 0.0826
Plasmodium falciparum protein kinase 5 0.0246 0.0463 0.0429
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0173 0.0181 0.0147
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0209 0.0319 0.0162
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.066 0.2072 0.2072
Brugia malayi Protein kinase domain containing protein 0.0246 0.0463 0.0463
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0248 0.0472 0.0472
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0935 0.3143 1
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0287 0.0624 0.0592
Trichomonas vaginalis AGC family protein kinase 0.0354 0.0884 0.2753
Echinococcus granulosus calcium dependent protein kinase 0.014 0.0052 0.0052
Echinococcus granulosus low density lipoprotein receptor ldl 0.0156 0.0113 0.0113
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0935 0.3143 0.3119
Brugia malayi Protein kinase domain containing protein 0.0398 0.1056 0.1056
Giardia lamblia Kinase, CMGC CDK 0.0246 0.0463 0.0965
Brugia malayi GCC2 and GCC3 family protein 0.0776 0.2525 0.2525
Schistosoma mansoni titin 0.0288 0.0627 0.0627
Schistosoma mansoni glutamate synthase 0.0248 0.0472 0.0472
Brugia malayi Protein kinase domain containing protein 0.0415 0.112 0.112
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.048 0.1371 0.1371
Echinococcus multilocularis Immunoglobulin subtype 0.0156 0.0113 0.0113
Echinococcus multilocularis twitchin 0.0201 0.0288 0.0288
Echinococcus multilocularis casein kinase I alpha 0.0225 0.0381 0.0381
Plasmodium falciparum calcium-dependent protein kinase 5 0.0209 0.0319 0.0285
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Schistosoma mansoni c4b-binding protein beta chain 0.0504 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Entamoeba histolytica p21-activated kinase 0.0194 0.026 0.079
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0472 0.0439
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Onchocerca volvulus 0.0273 0.0567 0.1984
Brugia malayi hypothetical protein 0.0135 0.0033 0.0033
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0253 0.049 0.049
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0173 0.0181 0.0147
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0316 0.0734 0.0734
Echinococcus multilocularis mitogen activated protein kinase 0.0173 0.0181 0.0181
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Entamoeba histolytica protein kinase, putative 0.0137 0.0039 0.0045
Echinococcus multilocularis protein kinase c epsilon type 0.0422 0.1147 0.1147
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0333 0.0801 0.0801
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0245 0.0462 0.0462
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni ste20-related kinase 0.0424 0.1155 0.1155
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.07 0.07
Schistosoma mansoni protein kinase 0.0178 0.02 0.02
Echinococcus granulosus biogenic amine 5HT receptor 0.1997 0.7272 0.7272
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0523 0.1597
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.022 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0381 0.0989 0.0989
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3143
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0419 0.1135 0.1135
Echinococcus granulosus delta-like protein 1 0.0273 0.0567 0.0567
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0459 0.1292 0.1292
Brugia malayi serine/threonine kinase 12 0.0243 0.0453 0.0453
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0827 0.0827
Trypanosoma cruzi cdc2-related kinase 1 0.0246 0.0463 0.0429
Loa Loa (eye worm) hypothetical protein 0.0184 0.0223 0.0223
Plasmodium vivax calcium-dependent protein kinase, putative 0.0209 0.0319 0.0162
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Onchocerca volvulus Neurogenic locus notch homolog 0.0273 0.0567 0.1984
Brugia malayi protein kinase C3,putative 0.0326 0.0775 0.0775
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3119
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Brugia malayi hypothetical protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) TK protein kinase 0.0383 0.0998 0.0998
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0248 0.0472 0.0472
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0175 0.0189 0.0154
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0935 0.3143 0.3119
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0381 0.0381
Schistosoma mansoni protein kinase 0.0757 0.2452 0.2452
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0243 0.0453 0.144
Echinococcus granulosus titin 0.0132 0.0021 0.0021
Echinococcus multilocularis activin receptor type 0.0136 0.0035 0.0035
Echinococcus multilocularis dual specificity 0.0287 0.0624 0.0624
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0299 0.0671 0.0671
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0273 0.0568 0.0568
Echinococcus granulosus Immunoglobulin 0.0522 0.1538 0.1538
Loa Loa (eye worm) hypothetical protein 0.0177 0.0196 0.0196
Toxoplasma gondii NADPH-glutathione reductase 0.0935 0.3143 0.3119
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.1476 0.1476
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1944 0.7066 0.7066
Brugia malayi EGF-like domain containing protein 0.0319 0.0746 0.0746
Entamoeba histolytica protein kinase , putative 0.0243 0.0453 0.144
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0463 0.1402
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0231 0.0404 0.0404
Brugia malayi RhoGAP domain containing protein 0.0154 0.0108 0.0108
Echinococcus multilocularis cyclin dependent kinase 0.0246 0.0463 0.0463
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0624 0.2016
Echinococcus multilocularis c src tyrosine kinase 0.0194 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0307 0.07 0.07
Brugia malayi Heparan sulfate 0.0156 0.0113 0.0113
Schistosoma mansoni cell adhesion molecule 0.0288 0.0627 0.0627
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Echinococcus granulosus ephrin type A receptor 4 A 0.0199 0.0282 0.0282
Echinococcus multilocularis roundabout 2 0.0307 0.07 0.07
Loa Loa (eye worm) thyroid receptor interactor 0.0211 0.0328 0.0328
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Echinococcus granulosus cyclin 0.0885 0.2947 0.2947
Loa Loa (eye worm) notch protein 0.0273 0.0567 0.0567
Echinococcus granulosus CDC7 cell division cycle 7 0.0186 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Giardia lamblia Kinase, STE STE20 0.0178 0.02 0.0079
Brugia malayi Protein kinase domain containing protein 0.1188 0.4125 0.4125
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0935 0.3143 0.3119
Brugia malayi Protein kinase domain containing protein 0.029 0.0635 0.0635
Loa Loa (eye worm) hypothetical protein 0.0522 0.1538 0.1538
Echinococcus granulosus serine:threonine protein kinase 0.0236 0.0425 0.0425
Echinococcus granulosus tyrosine protein kinase 0.0317 0.074 0.074
Echinococcus granulosus notch 0.0273 0.0567 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Echinococcus multilocularis neurogenic locus protein delta 0.0273 0.0567 0.0567
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0307 0.07 0.07
Brugia malayi Protein kinase domain containing protein 0.0236 0.0425 0.0425
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Echinococcus multilocularis 0.0132 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0448 0.125 0.3928
Trypanosoma brucei polo-like protein kinase 0.0558 0.1678 0.1649
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.1209 0.4209 0.4209
Schistosoma mansoni disulfide oxidoreductase 0.0248 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0231 0.0404 0.0404
Onchocerca volvulus 0.0273 0.0567 0.1984
Echinococcus granulosus nervana 2 0.0255 0.0499 0.0499
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus cyclin dependent kinase 19 0.1188 0.4125 0.4125
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0558 0.1678 0.1678
Trichomonas vaginalis CAMK family protein kinase 0.0238 0.0433 0.1306
Schistosoma mansoni titin 0.0151 0.0094 0.0094
Brugia malayi Protein kinase domain containing protein 0.1944 0.7066 0.7066
Schistosoma mansoni protein kinase 0.0896 0.2991 0.2991
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0266 0.0542 0.0509
Toxoplasma gondii EGF family domain-containing protein 0.0273 0.0567 0.0534
Trypanosoma cruzi aurora B kinase, putative 0.0243 0.0453 0.042
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0248 0.0472 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.06 0.1841 0.1841
Schistosoma mansoni g1/s-specific cyclin C 0.1768 0.6382 0.6382
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0169 0.0163 0.0163
Loa Loa (eye worm) LAD-2 short isoform 0.0156 0.0113 0.0113
Brugia malayi p70 ribosomal S6 kinase beta 0.0588 0.1793 0.1793
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0246 0.0463 0.0429
Echinococcus granulosus titin 0.022 0.0361 0.0361
Onchocerca volvulus 0.0132 0.0021 0.0012
Brugia malayi Prion-like- 0.0132 0.0021 0.0021
Echinococcus granulosus cyclin dependent kinase 1 0.0246 0.0463 0.0463
Schistosoma mansoni tyrosine kinase 0.0415 0.1122 0.1122
Loa Loa (eye worm) hypothetical protein 0.0373 0.0956 0.0956
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0375 0.0967 0.0967
Echinococcus granulosus serine/threonine protein kinase 0.0339 0.0827 0.0827
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0935 0.3143 1
Onchocerca volvulus 0.0132 0.0021 0.0012
Echinococcus granulosus dual specificity 0.0253 0.049 0.049
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0329 0.0786 0.0754
Brugia malayi Prion-like- 0.0132 0.0021 0.0021
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0318 0.0742 0.071
Trichomonas vaginalis CMGC family protein kinase 0.0186 0.023 0.0655
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0209 0.0319 0.0285
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Onchocerca volvulus 0.0504 0.1465 0.5225
Echinococcus multilocularis tyrosine protein kinase Srms 0.0257 0.0506 0.0506
Mycobacterium tuberculosis Probable oxidoreductase 0.0935 0.3143 0.2803
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0132 0.0021 0.0021
Schistosoma mansoni protein kinase 0.0398 0.1056 0.1056
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0452 0.1263 0.1263
Echinococcus granulosus cyclin dependent kinase 9 0.0184 0.0222 0.0222
Onchocerca volvulus 0.0186 0.023 0.0764
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0156 0.0113 0.0113
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0108 0.0108
Entamoeba histolytica casein kinase, putative 0.0225 0.0381 0.1197
Brugia malayi Doublecortin family protein 0.0312 0.0719 0.0719
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0486 0.1395 0.1395
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Plasmodium falciparum glutathione reductase 0.0935 0.3143 0.3119
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0132 0.0021 0.0021
Echinococcus multilocularis titin 0.0132 0.0021 0.0021
Echinococcus multilocularis serine:threonine protein kinase N2 0.0268 0.0547 0.0547
Echinococcus multilocularis serine:threonine protein kinase 0.0236 0.0425 0.0425
Onchocerca volvulus 0.0644 0.2012 0.7201
Trypanosoma brucei SNF1-related protein kinases, putative 0.0162 0.0137 0.0103
Echinococcus granulosus tyrosine kinase 0.0135 0.0033 0.0033
Echinococcus granulosus twitchin 0.0723 0.2319 0.2319
Brugia malayi Fes/CIP4 homology domain containing protein 0.0211 0.0328 0.0328
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0299 0.067 0.067
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0175 0.0186 0.0186
Onchocerca volvulus 0.0286 0.0621 0.2176
Entamoeba histolytica protein kinase, putative 0.0211 0.0329 0.102
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0246 0.0463 0.0463
Loa Loa (eye worm) Notch2 0.0273 0.0567 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0528 0.0528
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0935 0.3143 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0459 0.1292 0.1292
Brugia malayi SH2 domain containing protein 0.0452 0.1263 0.1263
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0156 0.0113 0.0113
Brugia malayi Furin-like cysteine rich region family protein 0.0716 0.2292 0.2292
Loa Loa (eye worm) hypothetical protein 0.0295 0.0653 0.0653
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0033 0.0026
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0175 0.0186 0.0151
Trichomonas vaginalis AGC family protein kinase 0.0186 0.023 0.0655
Onchocerca volvulus 0.0225 0.0381 0.1312
Echinococcus multilocularis casein kinase I delta 0.0225 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus tyrosine protein kinase ABL1 0.0135 0.0033 0.0033
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0175 0.0186 0.0186
Entamoeba histolytica protein kinase domain containing protein 0.0243 0.0453 0.144
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0286 0.0617 0.1898
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0181 0.0181
Giardia lamblia Kinase, CMGC GSK 0.0266 0.0542 0.1232
Trichomonas vaginalis CK1 family protein kinase 0.0225 0.0381 0.1141
Schistosoma mansoni netrin receptor unc5 0.0156 0.0113 0.0113
Loa Loa (eye worm) TK protein kinase 0.0189 0.0241 0.0241
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0225 0.0381 0.0381
Onchocerca volvulus Putative titin 0.0132 0.0021 0.0012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0173 0.0181 0.0147
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0472 0.0472
Echinococcus multilocularis epidermal growth factor receptor 0.0716 0.2292 0.2292
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0728 0.2338 0.2338
Plasmodium vivax protein kinase Crk2 0.0246 0.0463 0.0308
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0151 0.0094 0.0094
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0172 0.0176 0.0176
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0156 0.0113 0.0113
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0448 0.125 0.125
Trypanosoma brucei protein kinase, putative 0.0266 0.0542 0.0509
Echinococcus granulosus C type lectin domian containing protein 0.0504 0.1465 0.1465
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.1242 0.1242
Trichomonas vaginalis apoptosis inducing factor, putative 0.0248 0.0472 0.1433
Echinococcus granulosus insulin receptor 0.062 0.1918 0.1918
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1678 0.1649
Loa Loa (eye worm) animal heme peroxidase 0.0132 0.0021 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0504 0.1465 0.1465
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0814 0.2672 0.2672
Echinococcus granulosus glutamate synthase 0.0248 0.0472 0.0472
Entamoeba histolytica protein kinase, putative 0.0149 0.0086 0.0205
Brugia malayi casein kinase I 0.0225 0.0381 0.0381
Plasmodium falciparum glutathione reductase 0.2699 1 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0307 0.07 0.07
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0499 0.1448 0.1448
Schistosoma mansoni laminin gamma-3 chain 0.0273 0.0567 0.0567
Brugia malayi Peroxidasin 0.0289 0.0629 0.0629
Schistosoma mansoni tyrosine kinase 0.0194 0.0261 0.0261
Echinococcus granulosus down syndrome cell adhesion 0.0132 0.0021 0.0021
Brugia malayi Protein kinase domain containing protein 0.0253 0.049 0.049
Leishmania major protein kinase, putative 0.0318 0.0742 0.071
Echinococcus granulosus nephrin 0.0151 0.0094 0.0094
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0472 0.0439
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Trypanosoma brucei casein kinase I, isoform 2 0.0225 0.0381 0.0348
Echinococcus granulosus casein kinase I alpha 0.0225 0.0381 0.0381
Onchocerca volvulus 0.0603 0.1851 0.662
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0162 0.0137 0.0137
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0506 0.1476 0.1476
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0472 0.0318
Brugia malayi Immunoglobulin domain containing protein 0.0156 0.0113 0.0113
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0885 0.2947 0.2947
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0253 0.049 0.0457
Loa Loa (eye worm) hypothetical protein 0.0384 0.1002 0.1002
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0801 0.0801
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2699 1 1
Schistosoma mansoni protein kinase 0.0317 0.0738 0.0738
Trichomonas vaginalis CAMK family protein kinase 0.0209 0.0319 0.094
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0541 0.1611 0.1611
Echinococcus granulosus titin 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0591 0.0591
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0172 0.0176 0.0142
Echinococcus granulosus serine threonine protein kinase nrc 0.0324 0.0766 0.0766
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.07 0.07
Loa Loa (eye worm) TK/ALK protein kinase 0.0314 0.0727 0.0727
Brugia malayi SRC-1 0.0316 0.0734 0.0734
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0419 0.1135 0.1135
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0162 0.0137 0.0103
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0375 0.0965 0.0965
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0404 0.037
Brugia malayi Protein kinase domain containing protein 0.0448 0.125 0.125
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0339 0.0826 0.0826
Echinococcus granulosus N chimaerin 0.0154 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0263 0.0528 0.0528
Echinococcus granulosus tyrosine protein kinase Blk 0.0257 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0333 0.0801 0.0801
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0248 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.112 0.112
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0248 0.0472 0.0439
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0457 0.1282 0.1282
Loa Loa (eye worm) casein kinase 0.0372 0.0953 0.0953
Echinococcus granulosus Immunoglobulin 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Echinococcus granulosus protein jagged 2 0.0273 0.0567 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0266 0.0542 0.1656
Loa Loa (eye worm) TK/EGFR protein kinase 0.0716 0.2292 0.2292
Loa Loa (eye worm) TK/INSR protein kinase 0.062 0.1918 0.1918
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Plasmodium falciparum glycogen synthase kinase 3 0.0266 0.0542 0.0509
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Giardia lamblia Kinase, AGC AKT 0.0242 0.0449 0.0918
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1505 0.5358 0.5358
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0329 0.0786 0.0754
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0472 0.0439
Onchocerca volvulus Putative cubilin 0.0273 0.0567 0.1984
Echinococcus multilocularis CDC7 cell division cycle 7 0.0186 0.023 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.1395 0.1395
Echinococcus granulosus dual specificity 0.0287 0.0624 0.0624
Echinococcus granulosus neurogenic locus notch protein 4 0.0273 0.0567 0.0567
Entamoeba histolytica protein kinase, putative 0.0588 0.1793 0.595
Schistosoma mansoni myosin-binding protein-related 0.0151 0.0094 0.0094
Echinococcus granulosus raf serine:threonine protein kinase 0.0153 0.0104 0.0104
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.2338 0.2338
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) AGC/PKA protein kinase 0.0234 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0135 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Echinococcus granulosus c src tyrosine kinase 0.0194 0.0261 0.0261
Entamoeba histolytica protein kinase, putative 0.0266 0.0542 0.1738
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0463 0.0463
Loa Loa (eye worm) TK protein kinase 0.0257 0.0506 0.0506
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0246 0.0463 0.0463
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0419 0.1135 0.1135
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0181 0.0147
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0757 0.2452 0.2452
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0472 0.0439
Brugia malayi protein kinase C II. 0.0422 0.1147 0.1147
Schistosoma mansoni biogenic amine (5HT) receptor 0.1997 0.7272 0.7272
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0104 0.0104
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0132 0.0021 0.0021
Brugia malayi Disorganized muscle protein 1 0.0132 0.0021 0.0021
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0266 0.0542 0.0542
Onchocerca volvulus 0.0295 0.0653 0.2293
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.1147 0.1147
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0246 0.0463 0.0429
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0317 0.0738 0.0738
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0472 0.0439
Giardia lamblia Kinase, NEK 0.0282 0.0602 0.1434
Entamoeba histolytica hypothetical protein 0.0396 0.1047 0.344
Onchocerca volvulus 0.0135 0.0033 0.0055
Echinococcus granulosus hypothetical protein 0.0249 0.0475 0.0475
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Echinococcus multilocularis netrin receptor unc 5 0.0216 0.0345 0.0345
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0225 0.0381 0.0381
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0299 0.067 0.067
Brugia malayi Immunoglobulin domain containing protein 0.0156 0.0113 0.0113
Echinococcus multilocularis hemicentin 1 0.0288 0.0627 0.0627
Echinococcus multilocularis aurora kinase A 0.0243 0.0453 0.0453
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0113 0.0113
Echinococcus multilocularis protein jagged 1 0.0273 0.0567 0.0567
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Echinococcus multilocularis calcium dependent protein kinase 0.014 0.0052 0.0052
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0255 0.0499 0.0499
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0452 0.1263 0.1263
Echinococcus multilocularis dual specificity 0.0287 0.0624 0.0624
Schistosoma mansoni vav2 0.017 0.0168 0.0168
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0282 0.0602 0.0449
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0506 0.1476 0.1476
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0162 0.0137 0.0103
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0234 0.0416 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0236 0.0425 0.0425
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0318 0.0742 0.071
Echinococcus granulosus casein kinase i 0.0225 0.0381 0.0381
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0175 0.0186 0.0186
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0531 0.157 0.157
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Leishmania major protein kinase A catalytic subunit isoform 1 0.0234 0.0416 0.0383
Brugia malayi hypothetical protein 0.0459 0.1292 0.1292
Schistosoma mansoni serine/threonine protein kinase 0.1188 0.4125 0.4125
Brugia malayi Myb-like DNA-binding domain containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus insulin growth factor binding 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0319 0.0319
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0243 0.0453 0.144
Echinococcus multilocularis thioredoxin glutathione reductase 0.2699 1 1
Echinococcus granulosus calcium activated potassium channel 0.0279 0.0591 0.0591
Loa Loa (eye worm) AUR protein kinase 0.0243 0.0453 0.0453
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0316 0.0734 0.0734
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0639 0.1991 0.1991
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0207 0.0313 0.0156
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Toxoplasma gondii thioredoxin reductase 0.2699 1 1
Brugia malayi serine/threonine-protein kinase 6 0.0243 0.0453 0.0453
Plasmodium vivax serine/threonine protein kinase, putative 0.0172 0.0176 0.0017
Giardia lamblia Kinase, CMGC MAPK 0.0173 0.0181 0.0017
Echinococcus granulosus Immunoglobulin subtype 0.0156 0.0113 0.0113
Trichomonas vaginalis CK1 family protein kinase 0.0225 0.0381 0.1141
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0115 0.0115
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0472 0.1433
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Echinococcus multilocularis roundabout 2 0.0307 0.07 0.07
Toxoplasma gondii selenide, water dikinase 0.0248 0.0472 0.0439
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0172 0.0176 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Trichomonas vaginalis AGC family protein kinase 0.0234 0.0416 0.1253
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Schistosoma mansoni basigin related 0.0156 0.0113 0.0113
Echinococcus granulosus roundabout 2 0.0829 0.2731 0.2731
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0266 0.0542 0.0509
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0175 0.0189 0.0549
Schistosoma mansoni tyrosine kinase 0.0194 0.0261 0.0261
Loa Loa (eye worm) cyclin domain-containing protein 0.0885 0.2947 0.2947
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Loa Loa (eye worm) SRC-1 0.0316 0.0734 0.0734
Loa Loa (eye worm) glutathione reductase 0.2699 1 1
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Brugia malayi P38 map kinase family protein 2 0.0329 0.0786 0.0786
Plasmodium falciparum cGMP-dependent protein kinase 0.0175 0.0186 0.0151
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0479 0.1368 0.1368
Echinococcus granulosus casein kinase I gamma 0.0441 0.122 0.122
Echinococcus multilocularis down syndrome cell adhesion 0.0132 0.0021 0.0021
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0472 0.0472
Onchocerca volvulus 0.0504 0.1465 0.5225
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Echinococcus multilocularis Immunoglobulin 0.0156 0.0113 0.0113
Echinococcus granulosus leucine rich repeat containing protein 4 0.0132 0.0021 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.2699 1 1
Onchocerca volvulus Peroxidasin homolog 0.0133 0.0023 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.0425 0.1281
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0472 0.0472
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0266 0.0542 0.0542
Onchocerca volvulus 0.0186 0.023 0.0764
Echinococcus granulosus aurora kinase A 0.0243 0.0453 0.0453
Onchocerca volvulus 0.0135 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Onchocerca volvulus 0.0156 0.0115 0.0349
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Plasmodium falciparum calcium-dependent protein kinase 1 0.0209 0.0319 0.0285
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0827 0.2697
Echinococcus granulosus rho-associated protein kinase 1 0.0672 0.2118 0.2118
Trichomonas vaginalis CMGC family protein kinase 0.0186 0.023 0.0655
Onchocerca volvulus 0.0132 0.0021 0.0012
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0324 0.0766 0.0766
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0678 0.2144 0.2144
Schistosoma mansoni tyrosine kinase 0.0499 0.1448 0.1448
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0472 0.1433
Brugia malayi Protein kinase domain containing protein 0.0128 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0472 0.0472
Trypanosoma brucei protein kinase, putative 0.0191 0.0248 0.0214
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0375 0.0965 0.0965
Loa Loa (eye worm) TK/EPH protein kinase 0.0235 0.0423 0.0423
Schistosoma mansoni cell adhesion molecule 0.0307 0.07 0.07
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Trichomonas vaginalis AGC family protein kinase 0.0354 0.0884 0.2753
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.07 0.07
Echinococcus granulosus protein kinase c epsilon type 0.0422 0.1147 0.1147
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0404 0.0404
Echinococcus multilocularis expressed protein 0.0172 0.0176 0.0176
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Loa Loa (eye worm) hypothetical protein 0.0319 0.0746 0.0746
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0316 0.0734 0.0734
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Brugia malayi STE20-like kinase MST 0.0531 0.157 0.157
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0926 0.3108 0.3108
Entamoeba histolytica protein kinase domain containing protein 0.0266 0.0542 0.1738
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Brugia malayi Animal haem peroxidase family protein 0.0132 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.062 0.1918 0.1918
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0742 0.0742
Loa Loa (eye worm) hypothetical protein 0.0295 0.0653 0.0653
Echinococcus multilocularis c4b binding protein beta chain 0.0504 0.1465 0.1465
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0236 0.0425 0.0425
Brugia malayi Cadherin domain containing protein 0.0273 0.0568 0.0568
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0472 0.1433
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Plasmodium falciparum calcium-dependent protein kinase 3 0.0209 0.0319 0.0285
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0324 0.0766 0.0734
Schistosoma mansoni tyrosine kinase 0.0355 0.0888 0.0888
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0504 0.1465 0.5225
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0288 0.0627 0.0627
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Echinococcus multilocularis expressed conserved protein 0.0175 0.0186 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.1292 0.1292
Echinococcus multilocularis neural cadherin 0.0273 0.0568 0.0568
Echinococcus granulosus casein kinase I alpha 0.0225 0.0381 0.0381
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Echinococcus granulosus tyrosine protein kinase Src42A 0.0316 0.0734 0.0734
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0094 0.0094
Entamoeba histolytica hypothetical protein 0.0253 0.049 0.1564
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1997 0.7272 0.7272
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni slit 0.0273 0.0569 0.0569
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0935 0.3143 0.2803
Brugia malayi Hr1 repeat family protein 0.06 0.1841 0.1841
Trichomonas vaginalis STE family protein kinase 0.0175 0.0189 0.0523
Schistosoma mansoni vesicular amine transporter 0.0522 0.1538 0.1538
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0307 0.07 0.07
Echinococcus granulosus dual specificity 0.0287 0.0624 0.0624
Giardia lamblia Kinase, CMGC GSK 0.0266 0.0542 0.1232
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0156 0.0113 0.0113
Plasmodium vivax apical sushi protein, putative 0.0504 0.1465 0.1327
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0935 0.3143 0.3143
Leishmania major hypothetical protein, conserved 0.0248 0.0472 0.0439
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0231 0.0404 0.0404
Schistosoma mansoni basigin related 0.0156 0.0113 0.0113
Entamoeba histolytica protein kinase domain containing protein 0.0266 0.0542 0.1738
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Toxoplasma gondii casein kinase I 0.0225 0.0381 0.0348
Loa Loa (eye worm) TK/FAK protein kinase 0.0601 0.1844 0.1844
Schistosoma mansoni hypothetical protein 0.021 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Echinococcus granulosus Protein kinase C brain isozyme 0.0504 0.1465 0.1465
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Echinococcus multilocularis fibropellin Ia 0.0273 0.0567 0.0567
Toxoplasma gondii rhoptry neck protein RON1 0.0504 0.1465 0.1435
Onchocerca volvulus 0.0266 0.0542 0.1891
Plasmodium falciparum ferrodoxin reductase-like protein 0.0248 0.0472 0.0439
Loa Loa (eye worm) hypothetical protein 0.0397 0.1049 0.1049
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0339 0.0827 0.0795
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0307 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0472 0.0472
Schistosoma mansoni tyrosine kinase 0.0132 0.002 0.002
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0318 0.0742 0.071
Echinococcus multilocularis hypothetical protein 0.021 0.0325 0.0325
Loa Loa (eye worm) projectin 0.0151 0.0094 0.0094
Brugia malayi Protein kinase domain containing protein 0.04 0.1064 0.1064
Echinococcus multilocularis calcium activated potassium channel 0.0279 0.0591 0.0591
Giardia lamblia Kinase, NEK 0.0282 0.0602 0.1434
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0175 0.0189 0.0154
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0463 0.1471
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0316 0.0734 0.0734
Loa Loa (eye worm) CDC7 protein kinase 0.0186 0.023 0.023
Onchocerca volvulus 0.0248 0.0472 0.1641
Toxoplasma gondii AGC kinase 0.0234 0.0416 0.0383
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0162 0.0137 0.0103
Onchocerca volvulus Serine\/threonine kinase homolog 0.0339 0.0826 0.2917
Echinococcus multilocularis serine:threonine protein kinase N2 0.06 0.1841 0.1841
Entamoeba histolytica protein kinase, putative 0.0189 0.0241 0.0726
Echinococcus granulosus c4b binding protein beta chain 0.0504 0.1465 0.1465
Echinococcus granulosus tyrosine protein kinase Src42A 0.0192 0.0253 0.0253
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0243 0.0453 0.0453
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0179 0.0204 0.0045
Trichomonas vaginalis glutathione reductase, putative 0.0935 0.3143 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Onchocerca volvulus Serine\/threonine kinase homolog 0.0558 0.1678 0.5993
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0375 0.0965 0.0965
Schistosoma mansoni vam6/vps39 related 0.0231 0.0404 0.0404
Brugia malayi Fibronectin type III domain containing protein 0.0541 0.1611 0.1611
Echinococcus multilocularis protein tyrosine kinase 0.0595 0.1819 0.1819
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0316 0.0734 0.0734
Leishmania major trypanothione reductase 0.2699 1 1
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0287 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0199 0.0282 0.0282
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0339 0.0826 0.0826
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0155 0.0155
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0132 0.0021 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Echinococcus multilocularis insulin growth factor binding 0.0132 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Schistosoma mansoni cell adhesion molecule 0.0156 0.0113 0.0113
Echinococcus granulosus Glutaredoxin protein 5 0.0255 0.0499 0.0499
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0522 0.1538 0.1538
Echinococcus granulosus defective proboscis extension response 0.0522 0.1538 0.1538
Schistosoma mansoni septate junction protein 0.0288 0.0627 0.0627
Brugia malayi Casein kinase II, alpha chain 0.0207 0.0313 0.0313
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0266 0.0542 0.0542
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0154 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0286 0.0621 0.0621
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0472 0.0439
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0162 0.0137 0.0103
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0324 0.0766 0.0734
Echinococcus multilocularis death associated protein kinase 1 0.0919 0.3078 0.3078
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis serine:threonine protein kinase N2 0.0333 0.0801 0.0801
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Schistosoma mansoni septate junction protein 0.0156 0.0113 0.0113
Echinococcus granulosus NDR protein kinase 0.0333 0.0801 0.0801
Giardia lamblia Kinase, PLK 0.0558 0.1678 0.5061
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.1555 0.1555
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0248 0.0472 0.0472
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0318 0.0742 0.071
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0132 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0398 0.1056 0.1056
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0935 0.3143 0.3119
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0209 0.0319 0.0285
Echinococcus granulosus protein kinase C gamma type 0.0417 0.1129 0.1129
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0133 0.0023 0.0023
Brugia malayi Delta serrate ligand family protein 0.0273 0.0567 0.0567
Echinococcus multilocularis dual specificity 0.0253 0.049 0.049
Loa Loa (eye worm) hypothetical protein 0.0619 0.1914 0.1914
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0935 0.3143 0.3119
Schistosoma mansoni tyrosine kinase 0.0432 0.1187 0.1187
Brugia malayi Protein kinase domain containing protein 0.066 0.2072 0.2072
Schistosoma mansoni kinase 0.0596 0.1826 0.1826
Onchocerca volvulus 0.0504 0.1465 0.5225
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0248 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0885 0.2947 0.2947
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0156 0.0113 0.0113
Echinococcus granulosus tyrosine protein kinase Lyn 0.0384 0.1001 0.1001
Echinococcus multilocularis PAK box P21 Rho binding 0.0133 0.0026 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0935 0.3143 0.3032
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0178 0.02 0.02
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0243 0.0453 0.0299
Echinococcus granulosus slit 2 protein 0.0319 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0248 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0416 0.0416
Plasmodium falciparum NIMA related kinase 1 0.0282 0.0602 0.0569
Brugia malayi notch-like transmembrane receptor 0.0273 0.0567 0.0567
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0307 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0384 0.1002 0.1002
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0258 0.0509 0.0476
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0687 0.2179 0.2179
Echinococcus multilocularis hemicentin 1 0.0288 0.0627 0.0627
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0678 0.2144 0.2144
Onchocerca volvulus Peroxidasin homolog 0.0132 0.0021 0.0012
Schistosoma mansoni tyrosine kinase 0.0375 0.0965 0.0965
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Giardia lamblia NADH oxidase lateral transfer candidate 0.0935 0.3143 1
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0207 0.0313 0.0313
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0135 0.0033 0.0033
Plasmodium falciparum casein kinase 2, alpha subunit 0.0207 0.0313 0.0279
Echinococcus multilocularis serine:threonine protein kinase 3 0.0531 0.157 0.157
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0154 0.0108 0.0108
Echinococcus granulosus protein kinase c iota type 0.059 0.1802 0.1802
Schistosoma mansoni protein kinase 0.0243 0.0453 0.0453
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Schistosoma mansoni cell adhesion molecule 0.0132 0.0021 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi Sushi domain 0.0504 0.1465 0.1465
Brugia malayi Protein kinase domain containing protein 0.0926 0.3108 0.3108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni hemicentin 0.0151 0.0094 0.0094
Trichomonas vaginalis AGC family protein kinase 0.035 0.0868 0.2702
Echinococcus multilocularis casein kinase I delta 0.0225 0.0381 0.0381
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0935 0.3143 0.2803
Echinococcus multilocularis protein kinase c iota type 0.059 0.1802 0.1802
Trichomonas vaginalis AGC family protein kinase 0.0282 0.0602 0.1848
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Brugia malayi ephrin receptor 1 precursor 0.0129 0.001 0.001
Plasmodium falciparum protein serine/threonine kinase-1 0.0318 0.0742 0.071
Echinococcus granulosus neuroglian 0.0307 0.07 0.07
Schistosoma mansoni protein kinase 0.0178 0.02 0.02
Brugia malayi hypothetical protein 0.0541 0.1611 0.1611
Schistosoma mansoni tyrosine kinase 0.029 0.0634 0.0634
Schistosoma mansoni serine/threonine kinase 0.0333 0.0801 0.0801
Echinococcus granulosus expressed protein 0.0172 0.0176 0.0176
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0935 0.3143 1
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0165 0.015 0.015
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Plasmodium vivax ferrodoxin reductase, putative 0.0248 0.0472 0.0318
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0209 0.0319 0.0285
Echinococcus granulosus dual specificity 0.0287 0.0624 0.0624
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0404 0.0404
Brugia malayi Protein kinase domain containing protein 0.0354 0.0884 0.0884
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0248 0.0472 0.0439
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0165 0.015 0.015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0935 0.3143 1
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0266 0.0542 0.0509
Onchocerca volvulus 0.0135 0.0033 0.0055
Brugia malayi Protein kinase domain containing protein 0.066 0.2072 0.2072
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi cyclin-dependent kinase 9 0.0167 0.0155 0.0155
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0287 0.0624 0.0592
Echinococcus multilocularis slit 2 protein 0.0319 0.0746 0.0746
Loa Loa (eye worm) AUR protein kinase 0.0243 0.0453 0.0453
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0324 0.0766 0.0616
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0472 0.1342 0.1342
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0404 0.037
Toxoplasma gondii histone kinase SNF1, putative 0.0162 0.0137 0.0103
Echinococcus granulosus peroxidasin 0.0289 0.0629 0.0629
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0567 0.0567
Echinococcus multilocularis C type lectin domian containing protein 0.0504 0.1465 0.1465
Entamoeba histolytica protein kinase, putative 0.0243 0.0453 0.144
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.2338 0.2338
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Schistosoma mansoni septate junction protein 0.0288 0.0627 0.0627
Entamoeba histolytica protein kinase, putative 0.0253 0.049 0.1564
Brugia malayi Protein kinase domain containing protein 0.0441 0.122 0.122
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Echinococcus granulosus fibroblast growth factor receptor 4 0.0375 0.0965 0.0965
Echinococcus multilocularis 0.0199 0.0279 0.0279
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0288 0.0627 0.22
Echinococcus multilocularis peroxidasin 0.0289 0.0629 0.0629
Onchocerca volvulus 0.0273 0.0567 0.1984
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Loa Loa (eye worm) hypothetical protein 0.0811 0.2658 0.2658
Echinococcus multilocularis glutamate synthase 0.0248 0.0472 0.0472
Brugia malayi phosphoinositide-dependent protein kinase I 0.0169 0.0163 0.0163
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0288 0.0627 0.0627
Echinococcus granulosus fibropellin Ia 0.0273 0.0567 0.0567
Schistosoma mansoni roundabout 0.0288 0.0627 0.0627
Plasmodium vivax thioredoxin reductase, putative 0.2699 1 1
Trichomonas vaginalis CK1 family protein kinase 0.0225 0.0381 0.1141
Loa Loa (eye worm) hypothetical protein 0.0184 0.0223 0.0223
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.022 0.0361 0.1238
Onchocerca volvulus 0.0397 0.1049 0.3724
Trichomonas vaginalis AGC family protein kinase 0.037 0.0945 0.2948
Schistosoma mansoni protein kinase 0.0457 0.1282 0.1282
Echinococcus granulosus biogenic amine 5HT receptor 0.1209 0.4209 0.4209
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0472 0.0472
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi Protein kinase domain 0.0178 0.02 0.02
Echinococcus granulosus neurogenic locus notch protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0363 0.092 0.092
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0248 0.0472 0.0318
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3143
Echinococcus granulosus neural cadherin 0.0273 0.0568 0.0568
Entamoeba histolytica cyclin C, putative 0.0898 0.2996 1
Onchocerca volvulus 0.0231 0.0404 0.1393
Onchocerca volvulus 0.0273 0.0567 0.1984
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0248 0.0472 0.1433
Entamoeba histolytica serine/threonine protein kinase, putative 0.0162 0.0137 0.0375
Echinococcus multilocularis N chimaerin 0.0154 0.0108 0.0108
Leishmania major protein kinase, putative 0.0209 0.0319 0.0285
Echinococcus granulosus lachesin 0.0288 0.0627 0.0627
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0415 0.112 0.112
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0246 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0263 0.0528 0.0528
Onchocerca volvulus 0.0504 0.1465 0.5225
Loa Loa (eye worm) AUR protein kinase 0.0243 0.0453 0.0453
Trypanosoma cruzi Protein kinase B 0.0339 0.0827 0.0795
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus dual specificity protein kinase clk2 0.0318 0.0742 0.0742
Trypanosoma brucei NADH dehydrogenase 0.0248 0.0472 0.0439
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0273 0.0567 0.0567
Plasmodium vivax glycogen synthase kinase 3, putative 0.0266 0.0542 0.0389
Echinococcus multilocularis rac serine:threonine kinase 0.0339 0.0827 0.0827
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0094 0.0094
Echinococcus granulosus tyrosine protein kinase shark 0.0358 0.0898 0.0898
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0312 0.0719 0.0719
Plasmodium falciparum thioredoxin reductase 0.2699 1 1
Onchocerca volvulus 0.0381 0.0989 0.3505
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus neurogenic locus notch protein 0.0273 0.0567 0.0567
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0479 0.1368 0.1368
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0687 0.2178 0.2178
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0329 0.0786 0.0754
Loa Loa (eye worm) hypothetical protein 0.0209 0.0319 0.0319
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3143
Loa Loa (eye worm) hypothetical protein 0.0231 0.0404 0.0404
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0186 0.023 0.023
Giardia lamblia Kinase, STE STE20 0.0175 0.0189 0.0042
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0253 0.049 0.0457
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0567 0.0567
Schistosoma mansoni cell adhesion molecule 0.0151 0.0094 0.0094
Brugia malayi casein kinase 1, delta 0.0225 0.0381 0.0381
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0472 0.1433
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0827 0.2697
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0472 0.0472
Schistosoma mansoni tyrosine kinase 0.0316 0.0734 0.0734
Entamoeba histolytica casein kinase 1, putative 0.0225 0.0381 0.1197
Leishmania major hypothetical protein, conserved 0.0248 0.0472 0.0439
Entamoeba histolytica protein kinase 2, putative 0.0324 0.0766 0.2493
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus granulosus casein kinase I delta 0.0225 0.0381 0.0381
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.163 0.163
Treponema pallidum NADH oxidase 0.0935 0.3143 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0624 0.0592
Loa Loa (eye worm) hypothetical protein 0.0162 0.0137 0.0137
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Schistosoma mansoni protein kinase 0.0457 0.1282 0.1282
Echinococcus multilocularis cyclin dependent kinase 5 0.0246 0.0463 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.1242 0.1242
Echinococcus granulosus Vam6:Vps39 protein 0.0231 0.0404 0.0404
Onchocerca volvulus 0.0504 0.1465 0.5225
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0199 0.0282 0.0282
Echinococcus multilocularis cyclin dependent kinase 1 0.0246 0.0463 0.0463
Echinococcus multilocularis transfer RNA-Phe 0.0151 0.0094 0.0094
Trypanosoma cruzi cdc2-related kinase 3 0.0246 0.0463 0.0429
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0209 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0234 0.0416 0.0383
Entamoeba histolytica casein kinase, putative 0.0207 0.0313 0.0966
Echinococcus granulosus epidermal growth factor receptor 0.0499 0.1448 0.1448
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0094 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0576 0.1745 0.5514
Brugia malayi Immunoglobulin I-set domain containing protein 0.0178 0.0199 0.0199
Brugia malayi basement membrane proteoglycan precursor 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni tyrosine kinase 0.0716 0.2292 0.2292
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0173 0.0181 0.0147
Echinococcus multilocularis protein jagged 1 0.0273 0.0567 0.0567
Loa Loa (eye worm) CAMK protein kinase 0.022 0.0361 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0463 0.0463
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0156 0.0113 0.0113
Echinococcus granulosus serine:threonine protein kinase 0.0236 0.0425 0.0425
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0472 0.0439
Echinococcus granulosus protein jagged 2 0.0273 0.0567 0.0567
Schistosoma mansoni cell adhesion molecule 0.0307 0.07 0.07
Giardia lamblia Kinase, CAMK CAMKL 0.0179 0.0204 0.0093
Entamoeba histolytica protein kinase, putative 0.0172 0.0176 0.0507
Loa Loa (eye worm) TK/ROR protein kinase 0.0199 0.0282 0.0282
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0156 0.0115 0.008
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0234 0.0416 0.0416
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0175 0.0189 0.0549
Onchocerca volvulus 0.0132 0.0021 0.0012
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0318 0.0742 0.071
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0246 0.0463 0.0429
Brugia malayi Protein kinase domain containing protein 0.0317 0.074 0.074
Giardia lamblia Kinase, CK1 Casein kinase 0.0225 0.0381 0.0691
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0248 0.0472 0.0439
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi probable protein kinase 0.0547 0.1635 0.1635
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0178 0.02 0.02
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0282 0.0602 0.0569
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0192 0.0253 0.0253
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0354 0.0884 0.0884
Loa Loa (eye worm) disorganized muscle protein 1 0.0132 0.0021 0.0021
Trypanosoma brucei rac serine-threonine kinase, putative 0.0604 0.1854 0.1825
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.049 0.049
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0504 0.1465 0.1465
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Echinococcus multilocularis cyclin dependent kinase 9 0.0184 0.0222 0.0222
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1188 0.4125 0.4125
Loa Loa (eye worm) AGC/AKT protein kinase 0.0604 0.1854 0.1854
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1678 0.1649
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0173 0.0181 0.0147
Brugia malayi Leucine Rich Repeat family protein 0.0133 0.0023 0.0023
Entamoeba histolytica protein kinase, putative 0.0604 0.1854 0.6155
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0588 0.1793 0.1793
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0175 0.0186 0.0186
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.1465 0.1465
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0506 0.1476 0.1476
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.022 0.0361 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0416 0.0416
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0316 0.0734 0.0734
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0316 0.0734 0.0734
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0522 0.1538 0.1538
Echinococcus multilocularis serotonin receptor 0.1209 0.4209 0.4209
Leishmania major protein kinase A catalytic subunit isoform 2 0.0234 0.0416 0.0383
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0757 0.2452 0.2452
Trichomonas vaginalis CMGC family protein kinase 0.0318 0.0742 0.2298
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0248 0.0472 0.0472
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.0504 0.1465 0.5225
Echinococcus granulosus cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Echinococcus granulosus titin 0.0132 0.0021 0.0021
Toxoplasma gondii aurora kinase 0.0243 0.0453 0.042
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0273 0.0567 0.0567
Echinococcus multilocularis serine:threonine protein kinase 0.0236 0.0425 0.0425
Schistosoma mansoni serine/threonine protein kinase 0.0728 0.2338 0.2338
Brugia malayi Protein kinase domain containing protein 0.0604 0.1854 0.1854
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0225 0.0381 0.0381
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Muscle positioning protein 4 0.0273 0.0567 0.0567
Echinococcus granulosus growth factor receptor bound protein 2 0.0129 0.0008 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0541 0.1611 0.1611
Plasmodium falciparum apical sushi protein 0.0504 0.1465 0.1435
Trypanosoma brucei Casein kinase II 0.0207 0.0313 0.0279
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0472 0.0439
Echinococcus multilocularis dual specificity protein kinase clk2 0.0318 0.0742 0.0742
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Schistosoma mansoni glutamate synthase 0.0248 0.0472 0.0472
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0167 0.0155 0.0155
Schistosoma mansoni basigin related 0.0156 0.0113 0.0113
Schistosoma mansoni tyrosine kinase 0.062 0.1918 0.1918
Schistosoma mansoni hypothetical protein 0.021 0.0325 0.0325
Giardia lamblia Kinase, CMGC CLK 0.0318 0.0742 0.1907
Entamoeba histolytica protein kinase, putative 0.0209 0.0319 0.0986
Entamoeba histolytica protein kinase, putative 0.0287 0.0624 0.2016
Echinococcus multilocularis serine threonine protein kinase 0.0417 0.1129 0.1129
Schistosoma mansoni protein kinase C mu 0.045 0.1255 0.1255
Loa Loa (eye worm) CAMK/PKD protein kinase 0.045 0.1255 0.1255
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0266 0.0542 0.0542
Echinococcus multilocularis tyrosine protein kinase otk 0.0288 0.0627 0.0627
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0172 0.0176 0.0142
Echinococcus granulosus c-Jun N-terminal kinases 0.0546 0.163 0.163
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Onchocerca volvulus 0.0132 0.0021 0.001
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0234 0.0416 0.0383
Schistosoma mansoni ephrin receptor 0.0199 0.0282 0.0282
Echinococcus granulosus netrin receptor unc 5 0.0216 0.0345 0.0345
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0935 0.3143 0.2803
Echinococcus granulosus contactin 0.0307 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Plasmodium falciparum thioredoxin reductase 0.0935 0.3143 0.3119
Echinococcus multilocularis cyclin 0.0885 0.2947 0.2947
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.0132 0.0021 0.0012
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0814 0.2672 0.2672
Echinococcus multilocularis raf serine:threonine protein kinase 0.0153 0.0104 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0624 0.0624
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0209 0.0319 0.0162
Echinococcus granulosus cyclin dependent kinase 5 0.0246 0.0463 0.0463
Onchocerca volvulus 0.0132 0.0021 0.0012
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0153 0.0102 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0472 0.0439
Echinococcus multilocularis mitogen activated protein kinase 3 0.0173 0.0181 0.0181
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0248 0.0472 0.0472
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0266 0.0542 0.0542
Schistosoma mansoni septate junction protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) TK protein kinase 0.0317 0.074 0.074
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Onchocerca volvulus Netrin receptor homolog 0.0192 0.0253 0.0849
Loa Loa (eye worm) hypothetical protein 0.0776 0.2525 0.2525
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0156 0.0113 0.0113
Brugia malayi Cyclin, N-terminal domain containing protein 0.0885 0.2947 0.2947
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0248 0.0472 0.0439
Loa Loa (eye worm) protein kinase domain-containing protein 0.0441 0.122 0.122
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0459 0.1292 0.1292
Echinococcus multilocularis mitogen activated protein kinase 11 0.0329 0.0786 0.0786
Trichomonas vaginalis mercuric reductase, putative 0.0935 0.3143 1
Loa Loa (eye worm) hypothetical protein 0.0273 0.0568 0.0568
Echinococcus granulosus casein kinase ii subunit alpha 0.0207 0.0313 0.0313
Brugia malayi hypothetical protein 0.0231 0.0404 0.0404
Brugia malayi protein-tyrosine kinase 0.0257 0.0506 0.0506
Echinococcus multilocularis fat cadherin tumor suppressor 0.0273 0.0568 0.0568
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0169 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0249 0.0475 0.0475
Plasmodium falciparum serine/threonine protein kinase KIN 0.0162 0.0137 0.0103
Loa Loa (eye worm) hypothetical protein 0.0522 0.1538 0.1538
Schistosoma mansoni cell adhesion molecule 0.0151 0.0094 0.0094
Giardia lamblia Glutamate synthase 0.0248 0.0472 0.0998
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi Thioredoxin reductase 0.2699 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0318 0.0742 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0801 0.0801
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0318 0.0742 0.071
Giardia lamblia Kinase, AGC PKA 0.0324 0.0766 0.1988
Entamoeba histolytica protein kinase, putative 0.0169 0.0163 0.0463
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0339 0.0826 0.0826
Loa Loa (eye worm) hypothetical protein 0.0234 0.0416 0.0416
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0299 0.0671 0.0671
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.0728 0.2338 0.2338
Brugia malayi Protein kinase c protein 2 0.0239 0.0438 0.0438
Echinococcus multilocularis titin 0.0132 0.0021 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0419 0.1135 0.3735
Plasmodium vivax serine/threonine kinase-1, putative 0.0318 0.0742 0.0592
Echinococcus multilocularis casein kinase ii subunit alpha 0.0207 0.0313 0.0313
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0238 0.0433 0.0433
Echinococcus multilocularis tyrosine protein kinase HCK 0.0189 0.0241 0.0241
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0248 0.0472 0.0998
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0504 0.1465 0.5225
Plasmodium vivax unspecified product 0.0207 0.0313 0.0156
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0248 0.0472 0.1504
Brugia malayi Cadherin domain containing protein 0.0273 0.0568 0.0568
Giardia lamblia Kinase, AGC PKA 0.0234 0.0416 0.0809
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0523 0.1597
Brugia malayi Temporarily assigned gene name protein 59 0.0231 0.0404 0.0404
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0935 0.3143 1
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0238 0.0433 0.0433
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0137 0.0039 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Giardia lamblia Kinase, CMGC CDK 0.0246 0.0463 0.0965
Entamoeba histolytica protein kinase, putative 0.0172 0.0176 0.0507
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.066 0.2072 0.2072
Loa Loa (eye worm) gastrulation defective protein 1 0.1119 0.3858 0.3858
Loa Loa (eye worm) AGC/NDR protein kinase 0.0333 0.0801 0.0801
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Echinococcus granulosus Immunoglobulin 0.0156 0.0113 0.0113
Echinococcus granulosus mitogen activated protein kinase 14 0.0329 0.0786 0.0786
Schistosoma mansoni peroxidasin 0.0156 0.0115 0.0115
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Schistosoma mansoni netrin receptor unc5 0.0216 0.0345 0.0345
Brugia malayi Temporarily assigned gene name protein 59 0.0266 0.0542 0.0542
Loa Loa (eye worm) AGC/PKG protein kinase 0.0175 0.0186 0.0186
Schistosoma mansoni hypothetical protein 0.0151 0.0094 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0419 0.1135 0.1135
Plasmodium falciparum casein kinase 1 0.0225 0.0381 0.0348
Leishmania major NADH dehydrogenase, putative 0.0248 0.0472 0.0439
Schistosoma mansoni cell adhesion molecule 0.0156 0.0113 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0742 0.0742
Brugia malayi Egg laying defective protein 4 0.0175 0.0186 0.0186
Brugia malayi MAP kinase sur-1 0.0173 0.0181 0.0181
Echinococcus granulosus roundabout 2 0.0307 0.07 0.07
Giardia lamblia Kinase, CDC7 0.0186 0.023 0.018
Echinococcus multilocularis tyrosine protein kinase 0.0317 0.074 0.074
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.1209 0.4209 0.4209
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0248 0.0472 0.1504
Schistosoma mansoni tyrosine kinase 0.0358 0.0898 0.0898
Schistosoma mansoni protein kinase 0.0225 0.0381 0.0381
Giardia lamblia Aurora kinase 0.0243 0.0453 0.0934
Onchocerca volvulus 0.0504 0.1465 0.5225
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis neuroglian 0.0307 0.07 0.07
Echinococcus multilocularis tyrosine protein kinase Abl 0.0194 0.0261 0.0261
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0339 0.0823 0.0823
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0243 0.0453 0.144
Entamoeba histolytica protein kinase domain containing protein 0.0253 0.049 0.1564
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0209 0.0319 0.0319
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.045 0.1255 0.1255
Echinococcus multilocularis tyrosine protein kinase Blk 0.0257 0.0506 0.0506
Echinococcus granulosus cGMP dependent protein kinase 0.0175 0.0186 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Trypanosoma cruzi cdc2-related kinase 1 0.0246 0.0463 0.0429
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0108 0.0108
Schistosoma mansoni nephrin 0.0307 0.07 0.07
Echinococcus multilocularis insulin receptor 0.062 0.1918 0.1918
Echinococcus granulosus thioredoxin glutathione reductase 0.2699 1 1
Loa Loa (eye worm) TK protein kinase 0.0507 0.1479 0.1479
Brugia malayi Kinase associated domain 1 family protein 0.021 0.0325 0.0325
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0687 0.2179 0.2179
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1021 0.3476 0.3476
Loa Loa (eye worm) hypothetical protein 0.0307 0.07 0.07
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0728 0.2338 0.2338
Loa Loa (eye worm) TK/ABL protein kinase 0.0135 0.0033 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0223 0.0374 0.0374
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0168 0.0159 0.0125
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0472 0.1342 0.1342
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0248 0.0472 0.0439
Brugia malayi Cam kinase protein 1 0.0209 0.0319 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Loa Loa (eye worm) hypothetical protein 0.0541 0.1611 0.1611
Onchocerca volvulus Slit protein homolog 0.0319 0.0746 0.2627
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0935 0.3143 1
Entamoeba histolytica protein kinase, putative 0.0178 0.02 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0558 0.1678 0.1678
Echinococcus multilocularis tyrosine protein kinase shark 0.0358 0.0898 0.0898
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0472 0.1504
Brugia malayi Prion-like- 0.0132 0.0021 0.0021
Echinococcus granulosus casein kinase I delta 0.0225 0.0381 0.0381
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0163 0.0441
Brugia malayi Variant SH3 domain containing protein 0.0154 0.0108 0.0108
Schistosoma mansoni cell polarity protein 0.0273 0.0567 0.0567
Entamoeba histolytica disulphide oxidoreductase, putative 0.0248 0.0472 0.1504
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0162 0.0137 0.0103
Entamoeba histolytica protein kinase domain containing protein 0.0167 0.0155 0.0435
Brugia malayi serine/threonine-protein kinase PAK 7 0.048 0.1371 0.1371
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0415 0.112 0.112
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0546 0.163 0.163
Echinococcus granulosus titin 0.022 0.0361 0.0361
Leishmania major casein kinase, putative 0.0225 0.0381 0.0348
Loa Loa (eye worm) TK/FER protein kinase 0.0452 0.1263 0.1263
Toxoplasma gondii AGC kinase 0.0588 0.1793 0.1764
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0163 0.0163
Echinococcus granulosus protein jagged 1 0.0273 0.0567 0.0567
Echinococcus multilocularis Immunoglobulin 0.0156 0.0113 0.0113
Echinococcus multilocularis serotonin receptor 0.1209 0.4209 0.4209
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0591 0.0591
Onchocerca volvulus 0.0504 0.1465 0.5225
Loa Loa (eye worm) cyclin C 0.1768 0.6382 0.6382
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Loa Loa (eye worm) AGC/PKA protein kinase 0.0234 0.0416 0.0416
Schistosoma mansoni kinase 0.0167 0.0155 0.0155
Brugia malayi Immunoglobulin domain containing protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0811 0.2658 0.2658
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Echinococcus granulosus cyclin dependent kinase 9 0.0167 0.0155 0.0155
Entamoeba histolytica protein kinase, putative 0.0604 0.1854 0.6155
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Echinococcus granulosus activin receptor type 0.0136 0.0035 0.0035
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0329 0.0786 0.0786
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0472 0.1504
Echinococcus multilocularis serine:threonine protein kinase 38 0.0333 0.0801 0.0801
Loa Loa (eye worm) hypothetical protein 0.0523 0.154 0.154
Schistosoma mansoni titin 0.022 0.0361 0.0361
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0257 0.0506 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Schistosoma mansoni serine/threonine protein kinase 0.0814 0.2672 0.2672
Trichomonas vaginalis CMGC family protein kinase 0.0186 0.023 0.0655
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Giardia lamblia Kinase, CMGC DYRK 0.0287 0.0624 0.1511
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0728 0.2338 0.8377
Echinococcus multilocularis neurogenic locus notch protein 0.0273 0.0567 0.0567
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0546 0.163 0.163
Brugia malayi Tyrosine-protein kinase abl-1 0.0194 0.0261 0.0261
Echinococcus multilocularis nervana 2 0.0255 0.0499 0.0499
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Schistosoma mansoni serine/threonine protein kinase 0.0339 0.0826 0.0826
Echinococcus multilocularis titin 0.022 0.0361 0.0361
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) one IG domain family member 0.0132 0.0021 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Echinococcus granulosus epidermal growth factor receptor 0.0716 0.2292 0.2292
Echinococcus multilocularis protein kinase shaggy 0.0266 0.0542 0.0542
Brugia malayi C1-like domain containing protein 0.045 0.1255 0.1255
Echinococcus granulosus casein kinase I alpha 0.0225 0.0381 0.0381
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0248 0.0472 0.1504
Brugia malayi Stress-activated protein kinase jnk-1 0.0546 0.163 0.163
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0156 0.0113 0.0113
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0486 0.1395 0.1395
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0209 0.0319 0.0319
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0333 0.0801 0.0801
Loa Loa (eye worm) hypothetical protein 0.056 0.1685 0.1685
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0162 0.0137 0.0137
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus nervana 2 0.0255 0.0499 0.0499
Echinococcus multilocularis epidermal growth factor receptor 0.0499 0.1448 0.1448
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0234 0.0416 0.0383
Echinococcus multilocularis neurogenic locus notch protein 4 0.0273 0.0567 0.0567
Entamoeba histolytica serine/threonine protein kinase, putative 0.0558 0.1678 0.5562
Echinococcus granulosus serine:threonine protein kinase N2 0.06 0.1841 0.1841
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0234 0.0416 0.0261
Echinococcus multilocularis ephrin type A receptor 4 A 0.0199 0.0282 0.0282
Echinococcus multilocularis dual specificity 0.0287 0.0624 0.0624
Echinococcus multilocularis myosin iiia 0.0175 0.0189 0.0189
Giardia lamblia High cysteine protein 0.0273 0.0567 0.1318
Brugia malayi map kinase activated protein kinase protein 2 0.0814 0.2672 0.2672
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Echinococcus granulosus serine:threonine kinase SAD 1 0.0162 0.0137 0.0137
Schistosoma mansoni tyrosine kinase 0.0595 0.1819 0.1819
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0307 0.07 0.07
Schistosoma mansoni nephrin 0.0673 0.2125 0.2125
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0288 0.0288
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0234 0.0416 0.0383
Loa Loa (eye worm) hypothetical protein 0.0289 0.0629 0.0629
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0316 0.0734 0.0734
Loa Loa (eye worm) TK/KIN16 protein kinase 0.139 0.491 0.491
Loa Loa (eye worm) hypothetical protein 0.0217 0.0351 0.0351
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni hypothetical protein 0.0231 0.0404 0.0404
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0522 0.1538 0.1538
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0154 0.0108 0.0108
Giardia lamblia Thioredoxin reductase 0.0248 0.0472 0.0998
Trypanosoma brucei trypanothione reductase 0.2699 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.122 0.122
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0248 0.0472 0.1433
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Echinococcus multilocularis casein kinase I alpha 0.0225 0.0381 0.0381
Brugia malayi basement membrane proteoglycan 0.0156 0.0113 0.0113
Echinococcus multilocularis titin 0.0132 0.0021 0.0021
Leishmania major protein kinase A catalytic subunit 0.0234 0.0416 0.0383
Entamoeba histolytica protein kinase, putative 0.0149 0.0086 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.0238 0.0433 0.1306
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0935 0.3143 0.3032
Loa Loa (eye worm) hypothetical protein 0.021 0.0325 0.0325
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0209 0.0319 0.0285
Echinococcus multilocularis Glutaredoxin protein 5 0.0255 0.0499 0.0499
Trypanosoma brucei cdc2-related kinase 3 0.0246 0.0463 0.0429
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0194 0.0261 0.0261
Brugia malayi glutamate synthase 0.0248 0.0472 0.0472
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0035 0.0032
Echinococcus multilocularis cyclin dependent kinase 9 0.0167 0.0155 0.0155
Brugia malayi putative serine/threonine kinase SADA gamma 0.0162 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0231 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Echinococcus multilocularis casein kinase I gamma 0.0441 0.122 0.122
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0757 0.2452 0.2452
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0178 0.0199 0.0199
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0404 0.037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0216 0.0345 0.0345
Onchocerca volvulus 0.0273 0.0567 0.1984
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Echinococcus multilocularis nervana 2 0.0255 0.0499 0.0499
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0333 0.0801 0.0801
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0896 0.2991 0.2991
Echinococcus granulosus tyrosine protein kinase otk 0.0288 0.0627 0.0627
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0472 0.0439
Brugia malayi serine/threonine-protein kinase plk-2 0.0558 0.1678 0.1678
Schistosoma mansoni atypical protein kinase C 0.0603 0.1851 0.1851
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0457 0.1282 0.1282
Entamoeba histolytica protein kinase, putative 0.0253 0.049 0.1564
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0209 0.0319 0.0162
Echinococcus multilocularis 0.0317 0.0738 0.0738
Brugia malayi Immunoglobulin I-set domain containing protein 0.139 0.491 0.491
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0273 0.0567 0.1984
Echinococcus granulosus protein tyrosine kinase 0.0595 0.1819 0.1819
Onchocerca volvulus 0.0151 0.0094 0.0275
Echinococcus granulosus protein kinase shaggy 0.0266 0.0542 0.0542
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0624 0.0592
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Echinococcus granulosus protein kinase 0.0317 0.0738 0.0738
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0422 0.1147 0.1147
Loa Loa (eye worm) thioredoxin reductase 0.2699 1 1
Loa Loa (eye worm) AGC/PKN protein kinase 0.06 0.1841 0.1841
Brugia malayi Serine/threonine-protein kinase SULU 0.0459 0.1292 0.1292
Brugia malayi Cyclin C 0.1768 0.6382 0.6382
Giardia lamblia Kinase, CMGC CK2 0.0207 0.0313 0.046
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0257 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0601 0.1844 0.1844
Echinococcus granulosus mitogen activated protein kinase 3 0.0173 0.0181 0.0181
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0558 0.1678 0.1678
Echinococcus multilocularis casein kinase I alpha 0.0225 0.0381 0.0381
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0181 0.0147
Echinococcus multilocularis mitogen activated protein kinase 14 0.0329 0.0786 0.0786
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Schistosoma mansoni protein kinase 0.0207 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Entamoeba histolytica protein kinase domain containing protein 0.0207 0.0313 0.0966
Leishmania major protein kinase, putative 0.0243 0.0453 0.042
Loa Loa (eye worm) hypothetical protein 0.0541 0.1611 0.1611
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0728 0.2338 0.2338
Echinococcus multilocularis lachesin 0.0288 0.0627 0.0627
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0209 0.0319 0.0319
Schistosoma mansoni neuroglian 0.0307 0.07 0.07
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0173 0.0181 0.0181
Echinococcus multilocularis notch 0.0273 0.0567 0.0567
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0263 0.0528 0.0528
Echinococcus multilocularis 0.0249 0.0475 0.0475
Brugia malayi Protein kinase domain containing protein 0.0172 0.0176 0.0176
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0242 0.0449 0.0449
Trypanosoma cruzi cdc2-related kinase 3 0.0246 0.0463 0.0429
Echinococcus granulosus cyclin dependent kinase 0.0246 0.0463 0.0463
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0329 0.0786 0.0754
Echinococcus multilocularis Immunoglobulin 0.0522 0.1538 0.1538
Onchocerca volvulus 0.0133 0.0023 0.0019
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0234 0.0416 0.0383
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Entamoeba histolytica protein kinase, putative 0.0243 0.0453 0.144
Schistosoma mansoni slit 0.0133 0.0023 0.0023
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0248 0.0472 0.0472
Echinococcus granulosus mitogen activated protein kinase 0.0173 0.0181 0.0181
Brugia malayi Immunoglobulin I-set domain containing protein 0.0507 0.1479 0.1479
Echinococcus granulosus serine:threonine protein kinase 3 0.0531 0.157 0.157
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0234 0.0416 0.0383
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Echinococcus multilocularis casein kinase i 0.0225 0.0381 0.0381
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0639 0.1991 0.1991
Schistosoma mansoni septate junction protein 0.0273 0.0567 0.0567
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0151 0.0094 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0286 0.0621 0.0621
Echinococcus multilocularis tyrosine kinase 0.0135 0.0033 0.0033
Plasmodium falciparum serine/threonine protein kinase, putative 0.0243 0.0453 0.042
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Echinococcus granulosus tyrosine protein kinase HCK 0.0189 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.0135 0.0033 0.0055
Echinococcus granulosus tyrosine protein kinase Src64B 0.0316 0.0734 0.0734
Schistosoma mansoni protein kinase 0.0896 0.2991 0.2991
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0248 0.0472 0.0472
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0558 0.1678 0.1649
Schistosoma mansoni nephrin related 0.0132 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0248 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.023 0.023
Plasmodium falciparum serine/threonine protein kinase 0.0172 0.0176 0.0142
Schistosoma mansoni tyrosine kinase 0.0432 0.1187 0.1187
Brugia malayi Protein kinase domain containing protein 0.0318 0.0742 0.0742
Echinococcus multilocularis cyclin dependent kinase 1 0.0246 0.0463 0.0463
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0558 0.1678 0.1678
Trypanosoma brucei aurora B kinase 0.0243 0.0453 0.042
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0687 0.2178 0.2178
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0253 0.049 0.0457
Schistosoma mansoni tyrosine kinase 0.0499 0.1448 0.1448
Plasmodium falciparum calcium-dependent protein kinase 2 0.0209 0.0319 0.0285
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0415 0.112 0.112
Entamoeba histolytica thioredoxin reductase, putative 0.0248 0.0472 0.1504

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1080 nM In vitro binding affinity for Dopamine receptor D1 ChEMBL. 15689153
Ki (binding) = 3200 nM In vitro binding affinity for Dopamine receptor D2 ChEMBL. 15689153

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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