Detailed information for compound 312181

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 344.858 | Formula: C18H17ClN2OS
  • H donors: 1 H acceptors: 2 LogP: 4.77 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCc2c([C@H](C1)c1ccccc1)c1sc(nc1c(c2)Cl)O
  • InChi: 1S/C18H17ClN2OS/c1-21-8-7-12-9-14(19)16-17(23-18(22)20-16)15(12)13(10-21)11-5-3-2-4-6-11/h2-6,9,13H,7-8,10H2,1H3,(H,20,22)/t13-/m1/s1
  • InChiKey: CNZLLJPQLYIARX-CYBMUJFWSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni protein kinase 0.0243 0.0453 0.0453
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0135 0.0033 0.0033
Echinococcus multilocularis serine:threonine protein kinase 3 0.0531 0.157 0.157
Plasmodium falciparum casein kinase 2, alpha subunit 0.0207 0.0313 0.0279
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0154 0.0108 0.0108
Echinococcus granulosus protein kinase c iota type 0.059 0.1802 0.1802
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Schistosoma mansoni tyrosine kinase 0.0375 0.0965 0.0965
Giardia lamblia NADH oxidase lateral transfer candidate 0.0935 0.3143 1
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0207 0.0313 0.0313
Onchocerca volvulus Peroxidasin homolog 0.0132 0.0021 0.0012
Trichomonas vaginalis AGC family protein kinase 0.0282 0.0602 0.1848
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni hemicentin 0.0151 0.0094 0.0094
Trichomonas vaginalis AGC family protein kinase 0.035 0.0868 0.2702
Echinococcus multilocularis casein kinase I delta 0.0225 0.0381 0.0381
Echinococcus multilocularis protein kinase c iota type 0.059 0.1802 0.1802
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0935 0.3143 0.2803
Brugia malayi Sushi domain 0.0504 0.1465 0.1465
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi Protein kinase domain containing protein 0.0926 0.3108 0.3108
Schistosoma mansoni cell adhesion molecule 0.0132 0.0021 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0248 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0416 0.0416
Plasmodium falciparum NIMA related kinase 1 0.0282 0.0602 0.0569
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0935 0.3143 0.3032
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0243 0.0453 0.0299
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0178 0.02 0.02
Echinococcus granulosus slit 2 protein 0.0319 0.0746 0.0746
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0156 0.0113 0.0113
Echinococcus granulosus tyrosine protein kinase Lyn 0.0384 0.1001 0.1001
Echinococcus multilocularis PAK box P21 Rho binding 0.0133 0.0026 0.0026
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0248 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0885 0.2947 0.2947
Echinococcus multilocularis hemicentin 1 0.0288 0.0627 0.0627
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0678 0.2144 0.2144
Loa Loa (eye worm) hypothetical protein 0.0384 0.1002 0.1002
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0258 0.0509 0.0476
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0687 0.2179 0.2179
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0307 0.07 0.07
Brugia malayi notch-like transmembrane receptor 0.0273 0.0567 0.0567
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0935 0.3143 0.3119
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0209 0.0319 0.0285
Echinococcus granulosus protein kinase C gamma type 0.0417 0.1129 0.1129
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0398 0.1056 0.1056
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0132 0.0021 0.0021
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0318 0.0742 0.071
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Brugia malayi Protein kinase domain containing protein 0.066 0.2072 0.2072
Schistosoma mansoni kinase 0.0596 0.1826 0.1826
Onchocerca volvulus 0.0504 0.1465 0.5225
Echinococcus multilocularis dual specificity 0.0253 0.049 0.049
Loa Loa (eye worm) hypothetical protein 0.0619 0.1914 0.1914
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0935 0.3143 0.3119
Schistosoma mansoni tyrosine kinase 0.0432 0.1187 0.1187
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0133 0.0023 0.0023
Brugia malayi Delta serrate ligand family protein 0.0273 0.0567 0.0567
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0266 0.0542 0.0542
Brugia malayi Casein kinase II, alpha chain 0.0207 0.0313 0.0313
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0154 0.0108 0.0108
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Echinococcus granulosus defective proboscis extension response 0.0522 0.1538 0.1538
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0522 0.1538 0.1538
Schistosoma mansoni septate junction protein 0.0288 0.0627 0.0627
Echinococcus multilocularis insulin growth factor binding 0.0132 0.0021 0.0021
Schistosoma mansoni cell adhesion molecule 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus granulosus Glutaredoxin protein 5 0.0255 0.0499 0.0499
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0199 0.0282 0.0282
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0339 0.0826 0.0826
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0155 0.0155
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Giardia lamblia Kinase, PLK 0.0558 0.1678 0.5061
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.1555 0.1555
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0248 0.0472 0.0472
Echinococcus multilocularis serine:threonine protein kinase N2 0.0333 0.0801 0.0801
Schistosoma mansoni septate junction protein 0.0156 0.0113 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus NDR protein kinase 0.0333 0.0801 0.0801
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0324 0.0766 0.0734
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0162 0.0137 0.0103
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis death associated protein kinase 1 0.0919 0.3078 0.3078
Loa Loa (eye worm) hypothetical protein 0.0286 0.0621 0.0621
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0472 0.0439
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0246 0.0463 0.0463
Echinococcus multilocularis N chimaerin 0.0154 0.0108 0.0108
Entamoeba histolytica serine/threonine protein kinase, putative 0.0162 0.0137 0.0375
Leishmania major protein kinase, putative 0.0209 0.0319 0.0285
Echinococcus granulosus lachesin 0.0288 0.0627 0.0627
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0415 0.112 0.112
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0273 0.0567 0.0567
Plasmodium vivax glycogen synthase kinase 3, putative 0.0266 0.0542 0.0389
Echinococcus multilocularis rac serine:threonine kinase 0.0339 0.0827 0.0827
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus dual specificity protein kinase clk2 0.0318 0.0742 0.0742
Trypanosoma brucei NADH dehydrogenase 0.0248 0.0472 0.0439
Loa Loa (eye worm) AUR protein kinase 0.0243 0.0453 0.0453
Trypanosoma cruzi Protein kinase B 0.0339 0.0827 0.0795
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Onchocerca volvulus 0.0504 0.1465 0.5225
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0263 0.0528 0.0528
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0472 0.0472
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi Protein kinase domain 0.0178 0.02 0.02
Echinococcus granulosus neurogenic locus notch protein 0.0273 0.0567 0.0567
Onchocerca volvulus 0.0397 0.1049 0.3724
Schistosoma mansoni protein kinase 0.0457 0.1282 0.1282
Trichomonas vaginalis AGC family protein kinase 0.037 0.0945 0.2948
Echinococcus granulosus biogenic amine 5HT receptor 0.1209 0.4209 0.4209
Echinococcus granulosus fibropellin Ia 0.0273 0.0567 0.0567
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0288 0.0627 0.0627
Schistosoma mansoni roundabout 0.0288 0.0627 0.0627
Plasmodium vivax thioredoxin reductase, putative 0.2699 1 1
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Trichomonas vaginalis CK1 family protein kinase 0.0225 0.0381 0.1141
Loa Loa (eye worm) hypothetical protein 0.0184 0.0223 0.0223
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.022 0.0361 0.1238
Echinococcus multilocularis glutamate synthase 0.0248 0.0472 0.0472
Onchocerca volvulus 0.0273 0.0567 0.1984
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Loa Loa (eye worm) hypothetical protein 0.0811 0.2658 0.2658
Brugia malayi phosphoinositide-dependent protein kinase I 0.0169 0.0163 0.0163
Onchocerca volvulus 0.0231 0.0404 0.1393
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0248 0.0472 0.1433
Onchocerca volvulus 0.0273 0.0567 0.1984
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3143
Echinococcus granulosus neural cadherin 0.0273 0.0568 0.0568
Entamoeba histolytica cyclin C, putative 0.0898 0.2996 1
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0248 0.0472 0.0318
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0363 0.092 0.092
Toxoplasma gondii histone kinase SNF1, putative 0.0162 0.0137 0.0103
Echinococcus granulosus peroxidasin 0.0289 0.0629 0.0629
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0324 0.0766 0.0616
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0404 0.037
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0472 0.1342 0.1342
Echinococcus multilocularis slit 2 protein 0.0319 0.0746 0.0746
Loa Loa (eye worm) AUR protein kinase 0.0243 0.0453 0.0453
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi cyclin-dependent kinase 9 0.0167 0.0155 0.0155
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0287 0.0624 0.0592
Echinococcus granulosus fibroblast growth factor receptor 4 0.0375 0.0965 0.0965
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0288 0.0627 0.22
Echinococcus multilocularis peroxidasin 0.0289 0.0629 0.0629
Echinococcus multilocularis 0.0199 0.0279 0.0279
Schistosoma mansoni septate junction protein 0.0288 0.0627 0.0627
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Entamoeba histolytica protein kinase, putative 0.0253 0.049 0.1564
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Brugia malayi Protein kinase domain containing protein 0.0441 0.122 0.122
Entamoeba histolytica protein kinase, putative 0.0243 0.0453 0.144
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.2338 0.2338
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0567 0.0567
Echinococcus multilocularis C type lectin domian containing protein 0.0504 0.1465 0.1465
Schistosoma mansoni serine/threonine kinase 0.0333 0.0801 0.0801
Schistosoma mansoni tyrosine kinase 0.029 0.0634 0.0634
Plasmodium falciparum protein serine/threonine kinase-1 0.0318 0.0742 0.071
Echinococcus granulosus neuroglian 0.0307 0.07 0.07
Schistosoma mansoni protein kinase 0.0178 0.02 0.02
Brugia malayi hypothetical protein 0.0541 0.1611 0.1611
Brugia malayi ephrin receptor 1 precursor 0.0129 0.001 0.001
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0165 0.015 0.015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0935 0.3143 1
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0266 0.0542 0.0509
Brugia malayi Protein kinase domain containing protein 0.066 0.2072 0.2072
Onchocerca volvulus 0.0135 0.0033 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0248 0.0472 0.0439
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0404 0.0404
Brugia malayi Protein kinase domain containing protein 0.0354 0.0884 0.0884
Echinococcus granulosus expressed protein 0.0172 0.0176 0.0176
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0165 0.015 0.015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0935 0.3143 1
Plasmodium vivax ferrodoxin reductase, putative 0.0248 0.0472 0.0318
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Echinococcus granulosus dual specificity 0.0287 0.0624 0.0624
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0209 0.0319 0.0285
Giardia lamblia Kinase, CAMK CAMKL 0.0179 0.0204 0.0093
Loa Loa (eye worm) TK/ROR protein kinase 0.0199 0.0282 0.0282
Entamoeba histolytica protein kinase, putative 0.0172 0.0176 0.0507
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0156 0.0115 0.008
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0234 0.0416 0.0416
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Echinococcus granulosus protein jagged 2 0.0273 0.0567 0.0567
Schistosoma mansoni cell adhesion molecule 0.0307 0.07 0.07
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0463 0.0463
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0156 0.0113 0.0113
Echinococcus granulosus serine:threonine protein kinase 0.0236 0.0425 0.0425
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0472 0.0439
Schistosoma mansoni tyrosine kinase 0.0716 0.2292 0.2292
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Loa Loa (eye worm) CAMK protein kinase 0.022 0.0361 0.0361
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0173 0.0181 0.0147
Echinococcus multilocularis protein jagged 1 0.0273 0.0567 0.0567
Brugia malayi probable protein kinase 0.0547 0.1635 0.1635
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0178 0.02 0.02
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0282 0.0602 0.0569
Giardia lamblia Kinase, CK1 Casein kinase 0.0225 0.0381 0.0691
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0248 0.0472 0.0439
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0246 0.0463 0.0429
Brugia malayi Protein kinase domain containing protein 0.0317 0.074 0.074
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0175 0.0189 0.0549
Onchocerca volvulus 0.0132 0.0021 0.0012
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0318 0.0742 0.071
Echinococcus multilocularis transfer RNA-Phe 0.0151 0.0094 0.0094
Trypanosoma cruzi cdc2-related kinase 3 0.0246 0.0463 0.0429
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0209 0.0319 0.0319
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0199 0.0282 0.0282
Echinococcus multilocularis cyclin dependent kinase 1 0.0246 0.0463 0.0463
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Echinococcus granulosus Vam6:Vps39 protein 0.0231 0.0404 0.0404
Onchocerca volvulus 0.0504 0.1465 0.5225
Brugia malayi basement membrane proteoglycan precursor 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0576 0.1745 0.5514
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0094 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0178 0.0199 0.0199
Entamoeba histolytica casein kinase, putative 0.0207 0.0313 0.0966
Echinococcus granulosus epidermal growth factor receptor 0.0499 0.1448 0.1448
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0234 0.0416 0.0383
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus granulosus casein kinase I delta 0.0225 0.0381 0.0381
Treponema pallidum NADH oxidase 0.0935 0.3143 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.163 0.163
Schistosoma mansoni tyrosine kinase 0.0316 0.0734 0.0734
Entamoeba histolytica casein kinase 1, putative 0.0225 0.0381 0.1197
Leishmania major hypothetical protein, conserved 0.0248 0.0472 0.0439
Entamoeba histolytica protein kinase 2, putative 0.0324 0.0766 0.2493
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0827 0.2697
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0472 0.0472
Brugia malayi casein kinase 1, delta 0.0225 0.0381 0.0381
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0472 0.1433
Echinococcus multilocularis cyclin dependent kinase 5 0.0246 0.0463 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.1242 0.1242
Schistosoma mansoni protein kinase 0.0457 0.1282 0.1282
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Loa Loa (eye worm) hypothetical protein 0.0162 0.0137 0.0137
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0624 0.0592
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0479 0.1368 0.1368
Echinococcus granulosus neurogenic locus notch protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0312 0.0719 0.0719
Plasmodium falciparum thioredoxin reductase 0.2699 1 1
Onchocerca volvulus 0.0381 0.0989 0.3505
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0094 0.0094
Echinococcus granulosus tyrosine protein kinase shark 0.0358 0.0898 0.0898
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0567 0.0567
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Schistosoma mansoni cell adhesion molecule 0.0151 0.0094 0.0094
Giardia lamblia Kinase, STE STE20 0.0175 0.0189 0.0042
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0253 0.049 0.0457
Loa Loa (eye worm) hypothetical protein 0.0231 0.0404 0.0404
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0186 0.023 0.023
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0687 0.2178 0.2178
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0329 0.0786 0.0754
Loa Loa (eye worm) hypothetical protein 0.0209 0.0319 0.0319
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3143
Onchocerca volvulus 0.0132 0.0021 0.0012
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0814 0.2672 0.2672
Plasmodium falciparum thioredoxin reductase 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus multilocularis cyclin 0.0885 0.2947 0.2947
Echinococcus granulosus contactin 0.0307 0.07 0.07
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus netrin receptor unc 5 0.0216 0.0345 0.0345
Schistosoma mansoni ephrin receptor 0.0199 0.0282 0.0282
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0935 0.3143 0.2803
Echinococcus granulosus c-Jun N-terminal kinases 0.0546 0.163 0.163
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Onchocerca volvulus 0.0132 0.0021 0.001
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0234 0.0416 0.0383
Loa Loa (eye worm) TK protein kinase 0.0317 0.074 0.074
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Onchocerca volvulus Netrin receptor homolog 0.0192 0.0253 0.0849
Loa Loa (eye worm) hypothetical protein 0.0776 0.2525 0.2525
Echinococcus multilocularis mitogen activated protein kinase 3 0.0173 0.0181 0.0181
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0248 0.0472 0.0472
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0266 0.0542 0.0542
Schistosoma mansoni septate junction protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0132 0.0021 0.0012
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0153 0.0102 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0472 0.0439
Echinococcus multilocularis raf serine:threonine protein kinase 0.0153 0.0104 0.0104
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0624 0.0624
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0209 0.0319 0.0162
Echinococcus granulosus cyclin dependent kinase 5 0.0246 0.0463 0.0463
Schistosoma mansoni glutamate synthase 0.0248 0.0472 0.0472
Schistosoma mansoni basigin related 0.0156 0.0113 0.0113
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0167 0.0155 0.0155
Schistosoma mansoni tyrosine kinase 0.062 0.1918 0.1918
Schistosoma mansoni hypothetical protein 0.021 0.0325 0.0325
Giardia lamblia Kinase, CMGC CLK 0.0318 0.0742 0.1907
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0472 0.0439
Echinococcus multilocularis dual specificity protein kinase clk2 0.0318 0.0742 0.0742
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Echinococcus granulosus growth factor receptor bound protein 2 0.0129 0.0008 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0541 0.1611 0.1611
Plasmodium falciparum apical sushi protein 0.0504 0.1465 0.1435
Trypanosoma brucei Casein kinase II 0.0207 0.0313 0.0279
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Muscle positioning protein 4 0.0273 0.0567 0.0567
Echinococcus multilocularis tyrosine protein kinase otk 0.0288 0.0627 0.0627
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0172 0.0176 0.0142
Loa Loa (eye worm) CAMK/PKD protein kinase 0.045 0.1255 0.1255
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0266 0.0542 0.0542
Echinococcus multilocularis serine threonine protein kinase 0.0417 0.1129 0.1129
Schistosoma mansoni protein kinase C mu 0.045 0.1255 0.1255
Entamoeba histolytica protein kinase, putative 0.0209 0.0319 0.0986
Entamoeba histolytica protein kinase, putative 0.0287 0.0624 0.2016
Onchocerca volvulus 0.0504 0.1465 0.5225
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Echinococcus granulosus cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Echinococcus granulosus titin 0.0132 0.0021 0.0021
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0248 0.0472 0.0472
Trichomonas vaginalis CMGC family protein kinase 0.0318 0.0742 0.2298
Leishmania major protein kinase A catalytic subunit isoform 2 0.0234 0.0416 0.0383
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0757 0.2452 0.2452
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0416 0.0416
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0316 0.0734 0.0734
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0522 0.1538 0.1538
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0316 0.0734 0.0734
Echinococcus multilocularis serotonin receptor 0.1209 0.4209 0.4209
Brugia malayi Protein kinase domain containing protein 0.0604 0.1854 0.1854
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0225 0.0381 0.0381
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Schistosoma mansoni serine/threonine protein kinase 0.0728 0.2338 0.2338
Echinococcus multilocularis serine:threonine protein kinase 0.0236 0.0425 0.0425
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0273 0.0567 0.0567
Toxoplasma gondii aurora kinase 0.0243 0.0453 0.042
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1678 0.1649
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0173 0.0181 0.0147
Brugia malayi Leucine Rich Repeat family protein 0.0133 0.0023 0.0023
Echinococcus multilocularis cyclin dependent kinase 9 0.0184 0.0222 0.0222
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1188 0.4125 0.4125
Loa Loa (eye worm) AGC/AKT protein kinase 0.0604 0.1854 0.1854
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0504 0.1465 0.1465
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0192 0.0253 0.0253
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0354 0.0884 0.0884
Loa Loa (eye worm) disorganized muscle protein 1 0.0132 0.0021 0.0021
Trypanosoma brucei rac serine-threonine kinase, putative 0.0604 0.1854 0.1825
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.049 0.049
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.022 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.1465 0.1465
Brugia malayi Immunoglobulin I-set domain containing protein 0.0175 0.0186 0.0186
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0506 0.1476 0.1476
Entamoeba histolytica protein kinase, putative 0.0604 0.1854 0.6155
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0588 0.1793 0.1793
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0358 0.0898 0.0898
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0248 0.0472 0.1504
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.1209 0.4209 0.4209
Brugia malayi Egg laying defective protein 4 0.0175 0.0186 0.0186
Brugia malayi MAP kinase sur-1 0.0173 0.0181 0.0181
Echinococcus granulosus roundabout 2 0.0307 0.07 0.07
Giardia lamblia Kinase, CDC7 0.0186 0.023 0.018
Echinococcus multilocularis tyrosine protein kinase 0.0317 0.074 0.074
Echinococcus multilocularis neuroglian 0.0307 0.07 0.07
Echinococcus multilocularis tyrosine protein kinase Abl 0.0194 0.0261 0.0261
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Onchocerca volvulus 0.0504 0.1465 0.5225
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Giardia lamblia Aurora kinase 0.0243 0.0453 0.0934
Schistosoma mansoni protein kinase 0.0225 0.0381 0.0381
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Echinococcus granulosus Immunoglobulin 0.0156 0.0113 0.0113
Echinococcus granulosus mitogen activated protein kinase 14 0.0329 0.0786 0.0786
Schistosoma mansoni peroxidasin 0.0156 0.0115 0.0115
Loa Loa (eye worm) gastrulation defective protein 1 0.1119 0.3858 0.3858
Loa Loa (eye worm) AGC/NDR protein kinase 0.0333 0.0801 0.0801
Giardia lamblia Kinase, CMGC CDK 0.0246 0.0463 0.0965
Entamoeba histolytica protein kinase, putative 0.0172 0.0176 0.0507
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.066 0.2072 0.2072
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0742 0.0742
Schistosoma mansoni cell adhesion molecule 0.0156 0.0113 0.0113
Plasmodium falciparum casein kinase 1 0.0225 0.0381 0.0348
Leishmania major NADH dehydrogenase, putative 0.0248 0.0472 0.0439
Loa Loa (eye worm) AGC/PKG protein kinase 0.0175 0.0186 0.0186
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Brugia malayi Temporarily assigned gene name protein 59 0.0266 0.0542 0.0542
Schistosoma mansoni hypothetical protein 0.0151 0.0094 0.0094
Schistosoma mansoni netrin receptor unc5 0.0216 0.0345 0.0345
Schistosoma mansoni serine/threonine protein kinase 0.0419 0.1135 0.1135
Plasmodium vivax serine/threonine kinase-1, putative 0.0318 0.0742 0.0592
Entamoeba histolytica protein kinase domain containing protein 0.0419 0.1135 0.3735
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0238 0.0433 0.0433
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Echinococcus multilocularis casein kinase ii subunit alpha 0.0207 0.0313 0.0313
Echinococcus multilocularis tyrosine protein kinase HCK 0.0189 0.0241 0.0241
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0248 0.0472 0.0998
Onchocerca volvulus 0.0504 0.1465 0.5225
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Brugia malayi Protein kinase c protein 2 0.0239 0.0438 0.0438
Echinococcus multilocularis titin 0.0132 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0234 0.0416 0.0416
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0299 0.0671 0.0671
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.0728 0.2338 0.2338
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0318 0.0742 0.071
Giardia lamblia Kinase, AGC PKA 0.0324 0.0766 0.1988
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0339 0.0826 0.0826
Entamoeba histolytica protein kinase, putative 0.0169 0.0163 0.0463
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0238 0.0433 0.0433
Brugia malayi Temporarily assigned gene name protein 59 0.0231 0.0404 0.0404
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0935 0.3143 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0137 0.0039 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Giardia lamblia Kinase, AGC PKA 0.0234 0.0416 0.0809
Brugia malayi Cadherin domain containing protein 0.0273 0.0568 0.0568
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0523 0.1597
Plasmodium vivax unspecified product 0.0207 0.0313 0.0156
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0248 0.0472 0.1504
Echinococcus multilocularis fat cadherin tumor suppressor 0.0273 0.0568 0.0568
Loa Loa (eye worm) hypothetical protein 0.0273 0.0568 0.0568
Echinococcus granulosus casein kinase ii subunit alpha 0.0207 0.0313 0.0313
Brugia malayi protein-tyrosine kinase 0.0257 0.0506 0.0506
Brugia malayi hypothetical protein 0.0231 0.0404 0.0404
Loa Loa (eye worm) protein kinase domain-containing protein 0.0441 0.122 0.122
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0459 0.1292 0.1292
Trichomonas vaginalis mercuric reductase, putative 0.0935 0.3143 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.0329 0.0786 0.0786
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Brugia malayi Cyclin, N-terminal domain containing protein 0.0885 0.2947 0.2947
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0248 0.0472 0.0439
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0156 0.0113 0.0113
Brugia malayi Thioredoxin reductase 0.2699 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0318 0.0742 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0801 0.0801
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Giardia lamblia Glutamate synthase 0.0248 0.0472 0.0998
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0169 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0249 0.0475 0.0475
Plasmodium falciparum serine/threonine protein kinase KIN 0.0162 0.0137 0.0103
Schistosoma mansoni cell adhesion molecule 0.0151 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0522 0.1538 0.1538
Brugia malayi Tyrosine-protein kinase abl-1 0.0194 0.0261 0.0261
Echinococcus multilocularis nervana 2 0.0255 0.0499 0.0499
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Giardia lamblia Kinase, CMGC DYRK 0.0287 0.0624 0.1511
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0728 0.2338 0.8377
Echinococcus multilocularis neurogenic locus notch protein 0.0273 0.0567 0.0567
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0546 0.163 0.163
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0814 0.2672 0.2672
Trichomonas vaginalis CMGC family protein kinase 0.0186 0.023 0.0655
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0257 0.0506 0.0506
Schistosoma mansoni titin 0.022 0.0361 0.0361
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Echinococcus granulosus epidermal growth factor receptor 0.0716 0.2292 0.2292
Echinococcus multilocularis protein kinase shaggy 0.0266 0.0542 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) one IG domain family member 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0339 0.0826 0.0826
Echinococcus multilocularis titin 0.022 0.0361 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Onchocerca volvulus 0.0504 0.1465 0.5225
Loa Loa (eye worm) cyclin C 0.1768 0.6382 0.6382
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Echinococcus granulosus protein jagged 1 0.0273 0.0567 0.0567
Echinococcus multilocularis Immunoglobulin 0.0156 0.0113 0.0113
Echinococcus multilocularis serotonin receptor 0.1209 0.4209 0.4209
Toxoplasma gondii AGC kinase 0.0588 0.1793 0.1764
Loa Loa (eye worm) TK/FER protein kinase 0.0452 0.1263 0.1263
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0163 0.0163
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0472 0.1504
Echinococcus multilocularis serine:threonine protein kinase 38 0.0333 0.0801 0.0801
Loa Loa (eye worm) hypothetical protein 0.0523 0.154 0.154
Echinococcus granulosus activin receptor type 0.0136 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0329 0.0786 0.0786
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Echinococcus granulosus cyclin dependent kinase 9 0.0167 0.0155 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0453 0.0453
Entamoeba histolytica protein kinase, putative 0.0604 0.1854 0.6155
Loa Loa (eye worm) AGC/PKA protein kinase 0.0234 0.0416 0.0416
Schistosoma mansoni kinase 0.0167 0.0155 0.0155
Brugia malayi Immunoglobulin domain containing protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0811 0.2658 0.2658
Brugia malayi Prion-like- 0.0132 0.0021 0.0021
Echinococcus granulosus casein kinase I delta 0.0225 0.0381 0.0381
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0163 0.0441
Brugia malayi Variant SH3 domain containing protein 0.0154 0.0108 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Schistosoma mansoni cell polarity protein 0.0273 0.0567 0.0567
Entamoeba histolytica protein kinase, putative 0.0178 0.02 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0558 0.1678 0.1678
Echinococcus multilocularis tyrosine protein kinase shark 0.0358 0.0898 0.0898
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0472 0.1504
Loa Loa (eye worm) hypothetical protein 0.0541 0.1611 0.1611
Onchocerca volvulus Slit protein homolog 0.0319 0.0746 0.2627
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0935 0.3143 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0472 0.1342 0.1342
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0248 0.0472 0.0439
Brugia malayi Cam kinase protein 1 0.0209 0.0319 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0546 0.163 0.163
Echinococcus granulosus titin 0.022 0.0361 0.0361
Leishmania major casein kinase, putative 0.0225 0.0381 0.0348
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0415 0.112 0.112
Entamoeba histolytica disulphide oxidoreductase, putative 0.0248 0.0472 0.1504
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0162 0.0137 0.0103
Entamoeba histolytica protein kinase domain containing protein 0.0167 0.0155 0.0435
Brugia malayi serine/threonine-protein kinase PAK 7 0.048 0.1371 0.1371
Brugia malayi Kinase associated domain 1 family protein 0.021 0.0325 0.0325
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0687 0.2179 0.2179
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0108 0.0108
Schistosoma mansoni nephrin 0.0307 0.07 0.07
Trypanosoma cruzi cdc2-related kinase 1 0.0246 0.0463 0.0429
Echinococcus multilocularis insulin receptor 0.062 0.1918 0.1918
Echinococcus granulosus thioredoxin glutathione reductase 0.2699 1 1
Loa Loa (eye worm) TK protein kinase 0.0507 0.1479 0.1479
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.045 0.1255 0.1255
Echinococcus multilocularis tyrosine protein kinase Blk 0.0257 0.0506 0.0506
Echinococcus granulosus cGMP dependent protein kinase 0.0175 0.0186 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0243 0.0453 0.144
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0339 0.0823 0.0823
Entamoeba histolytica protein kinase domain containing protein 0.0253 0.049 0.1564
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0209 0.0319 0.0319
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0168 0.0159 0.0125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0223 0.0374 0.0374
Loa Loa (eye worm) TK/ABL protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0307 0.07 0.07
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1021 0.3476 0.3476
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0728 0.2338 0.2338
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0333 0.0801 0.0801
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0896 0.2991 0.2991
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0472 0.0439
Echinococcus granulosus tyrosine protein kinase otk 0.0288 0.0627 0.0627
Brugia malayi serine/threonine-protein kinase plk-2 0.0558 0.1678 0.1678
Echinococcus multilocularis nervana 2 0.0255 0.0499 0.0499
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Brugia malayi Immunoglobulin I-set domain containing protein 0.0216 0.0345 0.0345
Onchocerca volvulus 0.0273 0.0567 0.1984
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0757 0.2452 0.2452
Echinococcus multilocularis casein kinase I gamma 0.0441 0.122 0.122
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0404 0.037
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0178 0.0199 0.0199
Echinococcus granulosus protein kinase shaggy 0.0266 0.0542 0.0542
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0624 0.0592
Brugia malayi Immunoglobulin I-set domain containing protein 0.139 0.491 0.491
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0273 0.0567 0.1984
Echinococcus granulosus protein tyrosine kinase 0.0595 0.1819 0.1819
Onchocerca volvulus 0.0151 0.0094 0.0275
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0209 0.0319 0.0162
Entamoeba histolytica protein kinase, putative 0.0253 0.049 0.1564
Echinococcus multilocularis 0.0317 0.0738 0.0738
Schistosoma mansoni atypical protein kinase C 0.0603 0.1851 0.1851
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0457 0.1282 0.1282
Loa Loa (eye worm) hypothetical protein 0.021 0.0325 0.0325
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0209 0.0319 0.0285
Echinococcus multilocularis titin 0.0132 0.0021 0.0021
Entamoeba histolytica protein kinase, putative 0.0149 0.0086 0.0205
Leishmania major protein kinase A catalytic subunit 0.0234 0.0416 0.0383
Trichomonas vaginalis CAMK family protein kinase 0.0238 0.0433 0.1306
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0935 0.3143 0.3032
Brugia malayi basement membrane proteoglycan 0.0156 0.0113 0.0113
Echinococcus multilocularis casein kinase I alpha 0.0225 0.0381 0.0381
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0248 0.0472 0.1433
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus multilocularis cyclin dependent kinase 9 0.0167 0.0155 0.0155
Brugia malayi putative serine/threonine kinase SADA gamma 0.0162 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0231 0.0404 0.0404
Echinococcus multilocularis Glutaredoxin protein 5 0.0255 0.0499 0.0499
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0194 0.0261 0.0261
Trypanosoma brucei cdc2-related kinase 3 0.0246 0.0463 0.0429
Brugia malayi glutamate synthase 0.0248 0.0472 0.0472
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0288 0.0288
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0234 0.0416 0.0383
Loa Loa (eye worm) hypothetical protein 0.0289 0.0629 0.0629
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0316 0.0734 0.0734
Loa Loa (eye worm) TK/KIN16 protein kinase 0.139 0.491 0.491
Loa Loa (eye worm) hypothetical protein 0.0217 0.0351 0.0351
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0307 0.07 0.07
Schistosoma mansoni nephrin 0.0673 0.2125 0.2125
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Schistosoma mansoni tyrosine kinase 0.0595 0.1819 0.1819
Trypanosoma brucei trypanothione reductase 0.2699 1 1
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.122 0.122
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0154 0.0108 0.0108
Giardia lamblia Thioredoxin reductase 0.0248 0.0472 0.0998
Schistosoma mansoni hypothetical protein 0.0231 0.0404 0.0404
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0522 0.1538 0.1538
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0162 0.0137 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Echinococcus granulosus nervana 2 0.0255 0.0499 0.0499
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0486 0.1395 0.1395
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0209 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.056 0.1685 0.1685
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0333 0.0801 0.0801
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0248 0.0472 0.1504
Echinococcus granulosus casein kinase I alpha 0.0225 0.0381 0.0381
Brugia malayi Stress-activated protein kinase jnk-1 0.0546 0.163 0.163
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0156 0.0113 0.0113
Brugia malayi C1-like domain containing protein 0.045 0.1255 0.1255
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Echinococcus granulosus serine:threonine kinase SAD 1 0.0162 0.0137 0.0137
Giardia lamblia High cysteine protein 0.0273 0.0567 0.1318
Echinococcus multilocularis myosin iiia 0.0175 0.0189 0.0189
Brugia malayi map kinase activated protein kinase protein 2 0.0814 0.2672 0.2672
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0234 0.0416 0.0261
Echinococcus multilocularis ephrin type A receptor 4 A 0.0199 0.0282 0.0282
Echinococcus multilocularis dual specificity 0.0287 0.0624 0.0624
Echinococcus multilocularis epidermal growth factor receptor 0.0499 0.1448 0.1448
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0234 0.0416 0.0383
Echinococcus multilocularis neurogenic locus notch protein 4 0.0273 0.0567 0.0567
Echinococcus granulosus serine:threonine protein kinase N2 0.06 0.1841 0.1841
Entamoeba histolytica serine/threonine protein kinase, putative 0.0558 0.1678 0.5562
Plasmodium falciparum serine/threonine protein kinase 0.0172 0.0176 0.0142
Schistosoma mansoni tyrosine kinase 0.0432 0.1187 0.1187
Schistosoma mansoni hypothetical protein 0.0248 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.023 0.023
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0558 0.1678 0.1649
Schistosoma mansoni nephrin related 0.0132 0.0021 0.0021
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0415 0.112 0.112
Entamoeba histolytica thioredoxin reductase, putative 0.0248 0.0472 0.1504
Schistosoma mansoni tyrosine kinase 0.0499 0.1448 0.1448
Plasmodium falciparum calcium-dependent protein kinase 2 0.0209 0.0319 0.0285
Brugia malayi Protein kinase domain containing protein 0.0318 0.0742 0.0742
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0558 0.1678 0.1678
Echinococcus multilocularis cyclin dependent kinase 1 0.0246 0.0463 0.0463
Trypanosoma brucei aurora B kinase 0.0243 0.0453 0.042
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0687 0.2178 0.2178
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0253 0.049 0.0457
Loa Loa (eye worm) hypothetical protein 0.0286 0.0621 0.0621
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0591 0.0591
Echinococcus multilocularis tyrosine kinase 0.0135 0.0033 0.0033
Schistosoma mansoni septate junction protein 0.0273 0.0567 0.0567
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0639 0.1991 0.1991
Echinococcus multilocularis casein kinase i 0.0225 0.0381 0.0381
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0151 0.0094 0.0094
Echinococcus granulosus serine:threonine protein kinase 3 0.0531 0.157 0.157
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0234 0.0416 0.0383
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0248 0.0472 0.0472
Onchocerca volvulus 0.0135 0.0033 0.0055
Echinococcus granulosus tyrosine protein kinase Src64B 0.0316 0.0734 0.0734
Schistosoma mansoni protein kinase 0.0896 0.2991 0.2991
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Plasmodium falciparum serine/threonine protein kinase, putative 0.0243 0.0453 0.042
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0178 0.02 0.02
Echinococcus granulosus tyrosine protein kinase HCK 0.0189 0.0241 0.0241
Brugia malayi Protein kinase domain containing protein 0.0172 0.0176 0.0176
Echinococcus multilocularis notch 0.0273 0.0567 0.0567
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0263 0.0528 0.0528
Echinococcus multilocularis 0.0249 0.0475 0.0475
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0173 0.0181 0.0181
Schistosoma mansoni neuroglian 0.0307 0.07 0.07
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0728 0.2338 0.2338
Echinococcus multilocularis lachesin 0.0288 0.0627 0.0627
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0209 0.0319 0.0319
Entamoeba histolytica protein kinase, putative 0.0243 0.0453 0.144
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0248 0.0472 0.0472
Schistosoma mansoni slit 0.0133 0.0023 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0507 0.1479 0.1479
Echinococcus granulosus mitogen activated protein kinase 0.0173 0.0181 0.0181
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Echinococcus multilocularis Immunoglobulin 0.0522 0.1538 0.1538
Onchocerca volvulus 0.0133 0.0023 0.0019
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0234 0.0416 0.0383
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0242 0.0449 0.0449
Echinococcus granulosus cyclin dependent kinase 0.0246 0.0463 0.0463
Trypanosoma cruzi cdc2-related kinase 3 0.0246 0.0463 0.0429
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0329 0.0786 0.0754
Brugia malayi Cyclin C 0.1768 0.6382 0.6382
Giardia lamblia Kinase, CMGC CK2 0.0207 0.0313 0.046
Loa Loa (eye worm) AGC/PKN protein kinase 0.06 0.1841 0.1841
Brugia malayi Serine/threonine-protein kinase SULU 0.0459 0.1292 0.1292
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Echinococcus granulosus protein kinase 0.0317 0.0738 0.0738
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0422 0.1147 0.1147
Loa Loa (eye worm) thioredoxin reductase 0.2699 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Leishmania major protein kinase, putative 0.0243 0.0453 0.042
Entamoeba histolytica protein kinase domain containing protein 0.0207 0.0313 0.0966
Loa Loa (eye worm) hypothetical protein 0.0541 0.1611 0.1611
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0181 0.0147
Echinococcus multilocularis mitogen activated protein kinase 14 0.0329 0.0786 0.0786
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni protein kinase 0.0207 0.0313 0.0313
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0558 0.1678 0.1678
Echinococcus granulosus mitogen activated protein kinase 3 0.0173 0.0181 0.0181
Echinococcus multilocularis casein kinase I alpha 0.0225 0.0381 0.0381
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0257 0.0506 0.0506
Brugia malayi Protein kinase domain containing protein 0.0601 0.1844 0.1844
Echinococcus multilocularis neurogenic locus protein delta 0.0273 0.0567 0.0567
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0324 0.0766 0.0766
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.0186 0.023 0.023
Brugia malayi pregnancy-associated plasma protein-A 0.0504 0.1465 0.1465
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0169 0.0163 0.0163
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0287 0.0624 0.0624
Onchocerca volvulus 0.0135 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus granulosus protein jagged 1 0.0273 0.0567 0.0567
Echinococcus granulosus tyrosine kinase 0.0257 0.0506 0.0506
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0168 0.0161 0.0161
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0699 0.2225 0.2225
Plasmodium falciparum calcium-dependent protein kinase 4 0.0209 0.0319 0.0285
Schistosoma mansoni hypothetical protein 0.0273 0.0567 0.0567
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0253 0.049 0.0457
Schistosoma mansoni protein kinase 0.0547 0.1635 0.1635
Echinococcus granulosus basement membrane specific heparan sulfate 0.0156 0.0113 0.0113
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0477 0.152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Entamoeba histolytica cell division protein kinase 2, putative 0.0263 0.0529 0.1696
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0896 0.2991 0.2991
Brugia malayi intracellular kinase 0.0266 0.0542 0.0542
Schistosoma mansoni glutamate synthase 0.0248 0.0472 0.0472
Plasmodium vivax casein kinase 1, putative 0.0225 0.0381 0.0225
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni growth factor receptor-bound protein 0.0129 0.0008 0.0008
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0151 0.0094 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0361 0.0361
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0288 0.0627 0.0627
Brugia malayi serine/threonine protein kinase 6 0.0243 0.0453 0.0453
Echinococcus granulosus cGMP dependent protein kinase 1 0.0175 0.0186 0.0186
Schistosoma mansoni tyrosine kinase 0.0432 0.1187 0.1187
Loa Loa (eye worm) hypothetical protein 0.0286 0.0621 0.0621
Brugia malayi Protein kinase domain containing protein 0.0169 0.0163 0.0163
Echinococcus multilocularis NCK adaptor protein 0.0129 0.0008 0.0008
Brugia malayi protein unc-22 0.022 0.0361 0.0361
Trypanosoma cruzi trypanothione reductase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0416 0.0416
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0243 0.0453 0.0453
Echinococcus multilocularis mitogen activated protein kinase 14 0.0329 0.0786 0.0786
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0333 0.0801 0.0801
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0472 0.0439
Schistosoma mansoni serine/threonine protein kinase 0.0672 0.2118 0.2118
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0248 0.0472 0.0472
Toxoplasma gondii AGC kinase 0.0234 0.0416 0.0383
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0463 0.1402
Brugia malayi cell division control protein 2 homolog 0.0246 0.0463 0.0463
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus granulosus neurogenic locus protein delta 0.0273 0.0567 0.0567
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0135 0.0033 0.0055
Echinococcus multilocularis mitogen activated protein kinase 11 0.0329 0.0786 0.0786
Brugia malayi Prion-like- 0.0288 0.0627 0.0627
Echinococcus multilocularis roundabout 2 0.0829 0.2731 0.2731
Schistosoma mansoni protein kinase 0.0133 0.0026 0.0026
Leishmania major protein kinase, putative 0.0175 0.0189 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.1465 0.1465
Echinococcus multilocularis protein jagged 2 0.0273 0.0567 0.0567
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0935 0.3143 0.3119
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0318 0.0742 0.0742
Echinococcus granulosus roundabout 2 0.0307 0.07 0.07
Leishmania major hypothetical protein, conserved 0.0248 0.0472 0.0439
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0168 0.0159 0.0125
Giardia lamblia Kinase, CAMK CAMKL 0.0179 0.0204 0.0093
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0255 0.0499 0.0499
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0814 0.2672 0.2672
Schistosoma mansoni serine/threonine kinase 0.0466 0.1317 0.1317
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0234 0.0416 0.0383
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0172 0.0176 0.0142
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0246 0.0463 0.0463
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0186 0.0186
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Schistosoma mansoni cell adhesion molecule 0.0697 0.2217 0.2217
Leishmania major casein kinase II, putative 0.0207 0.0313 0.0279
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Trichomonas vaginalis STE family protein kinase 0.0282 0.0602 0.1848
Leishmania major protein kinase, putative 0.0318 0.0742 0.071
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0263 0.0528 0.0528
Brugia malayi Protein kinase domain containing protein 0.0314 0.0727 0.0727
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Brugia malayi SH2 domain containing protein 0.0135 0.0033 0.0033
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0175 0.0189 0.0154
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0463 0.1402
Echinococcus granulosus low density lipoprotein receptor ldl 0.0156 0.0113 0.0113
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0935 0.3143 0.3119
Trichomonas vaginalis AGC family protein kinase 0.0354 0.0884 0.2753
Echinococcus granulosus calcium dependent protein kinase 0.014 0.0052 0.0052
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.066 0.2072 0.2072
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0209 0.0319 0.0162
Brugia malayi Protein kinase domain containing protein 0.0246 0.0463 0.0463
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0248 0.0472 0.0472
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0287 0.0624 0.0592
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0935 0.3143 1
Plasmodium falciparum calcium-dependent protein kinase 5 0.0209 0.0319 0.0285
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Schistosoma mansoni c4b-binding protein beta chain 0.0504 0.1465 0.1465
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.048 0.1371 0.1371
Echinococcus multilocularis Immunoglobulin subtype 0.0156 0.0113 0.0113
Echinococcus multilocularis twitchin 0.0201 0.0288 0.0288
Echinococcus multilocularis casein kinase I alpha 0.0225 0.0381 0.0381
Brugia malayi GCC2 and GCC3 family protein 0.0776 0.2525 0.2525
Schistosoma mansoni glutamate synthase 0.0248 0.0472 0.0472
Schistosoma mansoni titin 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.0415 0.112 0.112
Brugia malayi Protein kinase domain containing protein 0.0398 0.1056 0.1056
Giardia lamblia Kinase, CMGC CDK 0.0246 0.0463 0.0965
Loa Loa (eye worm) hypothetical protein 0.0952 0.3209 0.3209
Toxoplasma gondii CMGC kinase, CK2 family 0.0207 0.0313 0.0279
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0173 0.0181 0.0147
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0472 0.0439
Echinococcus multilocularis rho associated protein kinase 0.0672 0.2118 0.2118
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0288 0.0627 0.0627
Schistosoma mansoni nephrin related 0.0156 0.0113 0.0113
Echinococcus granulosus neuroglian 0.0655 0.2052 0.2052
Plasmodium falciparum protein kinase 5 0.0246 0.0463 0.0429
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0173 0.0181 0.0147
Echinococcus granulosus mitogen activated protein kinase 11 0.0329 0.0786 0.0786
Brugia malayi Protein kinase domain containing protein 0.0339 0.0826 0.0826
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0827 0.0827
Trypanosoma brucei cdc2-related kinase 1 0.0246 0.0463 0.0429
Trypanosoma cruzi casein kinase II, putative 0.0207 0.0313 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0163 0.0441
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0234 0.0416 0.0383
Echinococcus granulosus serine:threonine protein kinase N2 0.0268 0.0547 0.0547
Echinococcus multilocularis Immunoglobulin 0.0522 0.1538 0.1538
Trypanosoma brucei hypothetical protein, conserved 0.0248 0.0472 0.0439
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0156 0.0113 0.0113
Brugia malayi Protein kinase domain containing protein 0.062 0.1918 0.1918
Echinococcus granulosus hemicentin 1 0.0288 0.0627 0.0627
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.1242 0.1242
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Echinococcus multilocularis neurogenic locus notch protein 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni protein kinase 0.0896 0.2991 0.2991
Entamoeba histolytica protein kinase, putative 0.0333 0.0801 0.2611
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0935 0.3143 0.3119
Loa Loa (eye worm) hypothetical protein 0.0151 0.0094 0.0094
Echinococcus multilocularis cyclin dependent kinase 19 0.1188 0.4125 0.4125
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0225 0.0381 0.0348
Plasmodium vivax glutathione reductase, putative 0.2699 1 1
Schistosoma mansoni tyrosine kinase 0.0316 0.0734 0.0734
Echinococcus multilocularis neuroglian 0.0655 0.2052 0.2052
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0419 0.1135 0.1135
Schistosoma mansoni protein kinase 0.0136 0.0035 0.0035
Onchocerca volvulus Tyrosine kinase homolog 0.0844 0.2787 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.025 0.0479 0.0479
Loa Loa (eye worm) programmed cell death 8 0.0248 0.0472 0.0472
Schistosoma mansoni biogenic amine (5HT) receptor 0.1209 0.4209 0.4209
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0477 0.152
Brugia malayi kettin 0.0132 0.0021 0.0021
Schistosoma mansoni rap gtpase-activating protein 0.0231 0.0404 0.0404
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.1395 0.1395
Brugia malayi Protein kinase domain containing protein 0.0757 0.2452 0.2452
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0133 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0985 0.3336 0.3336
Loa Loa (eye worm) hypothetical protein 0.066 0.2072 0.2072
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0234 0.0416 0.0416
Echinococcus granulosus tyrosine protein kinase Srms 0.056 0.1685 0.1685
Toxoplasma gondii rhoptry neck protein RON9 0.0504 0.1465 0.1435
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1021 0.3476 0.3476
Trichomonas vaginalis CMGC family protein kinase 0.0266 0.0542 0.1656
Loa Loa (eye worm) hypothetical protein 0.0557 0.1673 0.1673
Onchocerca volvulus 0.0132 0.0021 0.0012
Onchocerca volvulus 0.0672 0.2118 0.7583
Giardia lamblia Kinase, NEK 0.0282 0.0602 0.1434
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Brugia malayi Protein kinase domain containing protein 0.1188 0.4125 0.4125
Giardia lamblia Kinase, STE STE20 0.0178 0.02 0.0079
Echinococcus granulosus cyclin 0.0885 0.2947 0.2947
Loa Loa (eye worm) notch protein 0.0273 0.0567 0.0567
Echinococcus granulosus CDC7 cell division cycle 7 0.0186 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus multilocularis roundabout 2 0.0307 0.07 0.07
Loa Loa (eye worm) thyroid receptor interactor 0.0211 0.0328 0.0328
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Echinococcus granulosus ephrin type A receptor 4 A 0.0199 0.0282 0.0282
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Schistosoma mansoni cell adhesion molecule 0.0288 0.0627 0.0627
Trichomonas vaginalis CAMK family protein kinase 0.0448 0.125 0.3928
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Echinococcus multilocularis 0.0132 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Echinococcus granulosus serine:threonine protein kinase 0.0236 0.0425 0.0425
Echinococcus granulosus notch 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0522 0.1538 0.1538
Echinococcus granulosus tyrosine protein kinase 0.0317 0.074 0.074
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0307 0.07 0.07
Brugia malayi Protein kinase domain containing protein 0.0236 0.0425 0.0425
Echinococcus multilocularis neurogenic locus protein delta 0.0273 0.0567 0.0567
Brugia malayi Protein kinase domain containing protein 0.029 0.0635 0.0635
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0935 0.3143 0.3119
Echinococcus granulosus Immunoglobulin 0.0522 0.1538 0.1538
Loa Loa (eye worm) hypothetical protein 0.0177 0.0196 0.0196
Toxoplasma gondii NADPH-glutathione reductase 0.0935 0.3143 0.3119
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.1476 0.1476
Echinococcus multilocularis activin receptor type 0.0136 0.0035 0.0035
Echinococcus multilocularis dual specificity 0.0287 0.0624 0.0624
Echinococcus granulosus titin 0.0132 0.0021 0.0021
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0299 0.0671 0.0671
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0273 0.0568 0.0568
Schistosoma mansoni protein kinase 0.0757 0.2452 0.2452
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0243 0.0453 0.144
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Brugia malayi Heparan sulfate 0.0156 0.0113 0.0113
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0307 0.07 0.07
Echinococcus multilocularis cyclin dependent kinase 0.0246 0.0463 0.0463
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0624 0.2016
Echinococcus multilocularis c src tyrosine kinase 0.0194 0.0261 0.0261
Brugia malayi RhoGAP domain containing protein 0.0154 0.0108 0.0108
Brugia malayi EGF-like domain containing protein 0.0319 0.0746 0.0746
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1944 0.7066 0.7066
Entamoeba histolytica protein kinase , putative 0.0243 0.0453 0.144
Trichomonas vaginalis CMGC family protein kinase 0.0246 0.0463 0.1402
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0231 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0184 0.0223 0.0223
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Plasmodium vivax calcium-dependent protein kinase, putative 0.0209 0.0319 0.0162
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0459 0.1292 0.1292
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0827 0.0827
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0132 0.0021 0.0021
Brugia malayi serine/threonine kinase 12 0.0243 0.0453 0.0453
Trypanosoma cruzi cdc2-related kinase 1 0.0246 0.0463 0.0429
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0419 0.1135 0.1135
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3143
Echinococcus granulosus delta-like protein 1 0.0273 0.0567 0.0567
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0523 0.1597
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0381 0.0989 0.0989
Brugia malayi Immunoglobulin I-set domain containing protein 0.022 0.0361 0.0361
Loa Loa (eye worm) TK protein kinase 0.0383 0.0998 0.0998
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0248 0.0472 0.0472
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0175 0.0189 0.0154
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0935 0.3143 0.3119
Brugia malayi hypothetical protein 0.0156 0.0113 0.0113
Brugia malayi protein kinase C3,putative 0.0326 0.0775 0.0775
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0935 0.3143 0.3119
Onchocerca volvulus Neurogenic locus notch homolog 0.0273 0.0567 0.1984
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0253 0.049 0.049
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0173 0.0181 0.0147
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0316 0.0734 0.0734
Entamoeba histolytica p21-activated kinase 0.0194 0.026 0.079
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0472 0.0439
Onchocerca volvulus 0.0273 0.0567 0.1984
Brugia malayi hypothetical protein 0.0135 0.0033 0.0033
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Schistosoma mansoni protein kinase 0.0178 0.02 0.02
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Echinococcus granulosus biogenic amine 5HT receptor 0.1997 0.7272 0.7272
Loa Loa (eye worm) hypothetical protein 0.0245 0.0462 0.0462
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Schistosoma mansoni ste20-related kinase 0.0424 0.1155 0.1155
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.07 0.07
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0333 0.0801 0.0801
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0176 0.0176
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Echinococcus multilocularis mitogen activated protein kinase 0.0173 0.0181 0.0181
Entamoeba histolytica protein kinase, putative 0.0137 0.0039 0.0045
Echinococcus multilocularis protein kinase c epsilon type 0.0422 0.1147 0.1147
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus granulosus tyrosine kinase 0.0135 0.0033 0.0033
Echinococcus granulosus twitchin 0.0723 0.2319 0.2319
Brugia malayi Fes/CIP4 homology domain containing protein 0.0211 0.0328 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0528 0.0528
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0935 0.3143 1
Brugia malayi SH2 domain containing protein 0.0452 0.1263 0.1263
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0459 0.1292 0.1292
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Entamoeba histolytica protein kinase, putative 0.0211 0.0329 0.102
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0246 0.0463 0.0463
Loa Loa (eye worm) Notch2 0.0273 0.0567 0.0567
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0299 0.067 0.067
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0175 0.0186 0.0186
Onchocerca volvulus 0.0286 0.0621 0.2176
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0108 0.0108
Brugia malayi Doublecortin family protein 0.0312 0.0719 0.0719
Entamoeba histolytica casein kinase, putative 0.0225 0.0381 0.1197
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0486 0.1395 0.1395
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0156 0.0113 0.0113
Echinococcus granulosus cyclin dependent kinase 9 0.0184 0.0222 0.0222
Onchocerca volvulus 0.0186 0.023 0.0764
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0132 0.0021 0.0021
Schistosoma mansoni protein kinase 0.0398 0.1056 0.1056
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0452 0.1263 0.1263
Trypanosoma brucei SNF1-related protein kinases, putative 0.0162 0.0137 0.0103
Echinococcus multilocularis serine:threonine protein kinase N2 0.0268 0.0547 0.0547
Echinococcus multilocularis serine:threonine protein kinase 0.0236 0.0425 0.0425
Onchocerca volvulus 0.0644 0.2012 0.7201
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Plasmodium falciparum glutathione reductase 0.0935 0.3143 0.3119
Schistosoma mansoni hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0132 0.0021 0.0021
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Echinococcus multilocularis titin 0.0132 0.0021 0.0021
Echinococcus granulosus serine/threonine protein kinase 0.0339 0.0827 0.0827
Onchocerca volvulus 0.0132 0.0021 0.0012
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0935 0.3143 1
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0246 0.0463 0.0429
Echinococcus granulosus titin 0.022 0.0361 0.0361
Onchocerca volvulus 0.0132 0.0021 0.0012
Brugia malayi Prion-like- 0.0132 0.0021 0.0021
Echinococcus granulosus cyclin dependent kinase 1 0.0246 0.0463 0.0463
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0375 0.0967 0.0967
Loa Loa (eye worm) hypothetical protein 0.0373 0.0956 0.0956
Schistosoma mansoni tyrosine kinase 0.0415 0.1122 0.1122
Schistosoma mansoni serine/threonine protein kinase 0.06 0.1841 0.1841
Loa Loa (eye worm) LAD-2 short isoform 0.0156 0.0113 0.0113
Schistosoma mansoni g1/s-specific cyclin C 0.1768 0.6382 0.6382
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0169 0.0163 0.0163
Brugia malayi p70 ribosomal S6 kinase beta 0.0588 0.1793 0.1793
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0248 0.0472 0.0439
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0209 0.0319 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.0186 0.023 0.0655
Onchocerca volvulus 0.0504 0.1465 0.5225
Echinococcus multilocularis tyrosine protein kinase Srms 0.0257 0.0506 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Mycobacterium tuberculosis Probable oxidoreductase 0.0935 0.3143 0.2803
Brugia malayi Prion-like- 0.0132 0.0021 0.0021
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0318 0.0742 0.071
Echinococcus granulosus dual specificity 0.0253 0.049 0.049
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0329 0.0786 0.0754
Loa Loa (eye worm) hypothetical protein 0.0231 0.0404 0.0404
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.1209 0.4209 0.4209
Schistosoma mansoni disulfide oxidoreductase 0.0248 0.0472 0.0472
Trypanosoma brucei polo-like protein kinase 0.0558 0.1678 0.1649
Toxoplasma gondii EGF family domain-containing protein 0.0273 0.0567 0.0534
Trypanosoma cruzi aurora B kinase, putative 0.0243 0.0453 0.042
Schistosoma mansoni protein kinase 0.0896 0.2991 0.2991
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0266 0.0542 0.0509
Trichomonas vaginalis CAMK family protein kinase 0.0238 0.0433 0.1306
Brugia malayi Protein kinase domain containing protein 0.1944 0.7066 0.7066
Schistosoma mansoni titin 0.0151 0.0094 0.0094
Echinococcus granulosus nervana 2 0.0255 0.0499 0.0499
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Onchocerca volvulus 0.0273 0.0567 0.1984
Echinococcus granulosus cyclin dependent kinase 19 0.1188 0.4125 0.4125
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0558 0.1678 0.1678
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0162 0.0137 0.0103
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0375 0.0965 0.0965
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Loa Loa (eye worm) TK/ALK protein kinase 0.0314 0.0727 0.0727
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.07 0.07
Brugia malayi SRC-1 0.0316 0.0734 0.0734
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0419 0.1135 0.1135
Echinococcus granulosus titin 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0591 0.0591
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0172 0.0176 0.0142
Echinococcus granulosus serine threonine protein kinase nrc 0.0324 0.0766 0.0766
Brugia malayi Immunoglobulin I-set domain containing protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0541 0.1611 0.1611
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0263 0.0528 0.0528
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0339 0.0826 0.0826
Echinococcus granulosus N chimaerin 0.0154 0.0108 0.0108
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0404 0.037
Brugia malayi Protein kinase domain containing protein 0.0448 0.125 0.125
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0094 0.0094
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0506 0.1476 0.1476
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0472 0.0318
Echinococcus granulosus casein kinase I alpha 0.0225 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Onchocerca volvulus 0.0603 0.1851 0.662
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0162 0.0137 0.0137
Leishmania major protein kinase, putative 0.0318 0.0742 0.071
Echinococcus granulosus nephrin 0.0151 0.0094 0.0094
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0472 0.0439
Trypanosoma brucei casein kinase I, isoform 2 0.0225 0.0381 0.0348
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0209 0.0319 0.094
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2699 1 1
Schistosoma mansoni protein kinase 0.0317 0.0738 0.0738
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0801 0.0801
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Brugia malayi Immunoglobulin domain containing protein 0.0156 0.0113 0.0113
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0253 0.049 0.0457
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0885 0.2947 0.2947
Loa Loa (eye worm) hypothetical protein 0.0384 0.1002 0.1002
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0504 0.1465 0.1465
Loa Loa (eye worm) animal heme peroxidase 0.0132 0.0021 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.1242 0.1242
Trichomonas vaginalis apoptosis inducing factor, putative 0.0248 0.0472 0.1433
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1678 0.1649
Echinococcus granulosus insulin receptor 0.062 0.1918 0.1918
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0448 0.125 0.125
Trypanosoma brucei protein kinase, putative 0.0266 0.0542 0.0509
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0156 0.0113 0.0113
Echinococcus granulosus C type lectin domian containing protein 0.0504 0.1465 0.1465
Echinococcus granulosus down syndrome cell adhesion 0.0132 0.0021 0.0021
Schistosoma mansoni tyrosine kinase 0.0194 0.0261 0.0261
Brugia malayi Protein kinase domain containing protein 0.0253 0.049 0.049
Brugia malayi Peroxidasin 0.0289 0.0629 0.0629
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0307 0.07 0.07
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0499 0.1448 0.1448
Schistosoma mansoni laminin gamma-3 chain 0.0273 0.0567 0.0567
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0814 0.2672 0.2672
Echinococcus granulosus glutamate synthase 0.0248 0.0472 0.0472
Entamoeba histolytica protein kinase, putative 0.0149 0.0086 0.0205
Brugia malayi casein kinase I 0.0225 0.0381 0.0381
Plasmodium falciparum glutathione reductase 0.2699 1 1
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Echinococcus granulosus tyrosine protein kinase ABL1 0.0135 0.0033 0.0033
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0175 0.0186 0.0186
Giardia lamblia Kinase, CMGC GSK 0.0266 0.0542 0.1232
Entamoeba histolytica protein kinase domain containing protein 0.0243 0.0453 0.144
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0181 0.0181
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0286 0.0617 0.1898
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0175 0.0186 0.0151
Trichomonas vaginalis AGC family protein kinase 0.0186 0.023 0.0655
Echinococcus multilocularis casein kinase I delta 0.0225 0.0381 0.0381
Onchocerca volvulus 0.0225 0.0381 0.1312
Loa Loa (eye worm) hypothetical protein 0.0295 0.0653 0.0653
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0033 0.0026
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0156 0.0113 0.0113
Brugia malayi Furin-like cysteine rich region family protein 0.0716 0.2292 0.2292
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0728 0.2338 0.2338
Loa Loa (eye worm) hypothetical protein 0.0151 0.0094 0.0094
Plasmodium vivax protein kinase Crk2 0.0246 0.0463 0.0308
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0172 0.0176 0.0176
Echinococcus multilocularis epidermal growth factor receptor 0.0716 0.2292 0.2292
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0472 0.0472
Trichomonas vaginalis CK1 family protein kinase 0.0225 0.0381 0.1141
Schistosoma mansoni netrin receptor unc5 0.0156 0.0113 0.0113
Loa Loa (eye worm) TK protein kinase 0.0189 0.0241 0.0241
Onchocerca volvulus Putative titin 0.0132 0.0021 0.0012
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0225 0.0381 0.0381
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0173 0.0181 0.0147
Echinococcus multilocularis calcium dependent protein kinase 0.014 0.0052 0.0052
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0452 0.1263 0.1263
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0255 0.0499 0.0499
Echinococcus multilocularis dual specificity 0.0287 0.0624 0.0624
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0282 0.0602 0.0449
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0506 0.1476 0.1476
Schistosoma mansoni vav2 0.017 0.0168 0.0168
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0113 0.0113
Echinococcus multilocularis aurora kinase A 0.0243 0.0453 0.0453
Echinococcus multilocularis protein jagged 1 0.0273 0.0567 0.0567
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0225 0.0381 0.0381
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0299 0.067 0.067
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0472 0.1433
Brugia malayi Immunoglobulin domain containing protein 0.0156 0.0113 0.0113
Echinococcus multilocularis hemicentin 1 0.0288 0.0627 0.0627
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0531 0.157 0.157
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Leishmania major protein kinase A catalytic subunit isoform 1 0.0234 0.0416 0.0383
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0175 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0236 0.0425 0.0425
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0318 0.0742 0.071
Echinococcus granulosus casein kinase i 0.0225 0.0381 0.0381
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0162 0.0137 0.0103
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0234 0.0416 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0248 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.1147 0.1147
Brugia malayi hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0132 0.0021 0.0021
Brugia malayi Disorganized muscle protein 1 0.0132 0.0021 0.0021
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0266 0.0542 0.0542
Onchocerca volvulus 0.0295 0.0653 0.2293
Schistosoma mansoni biogenic amine (5HT) receptor 0.1997 0.7272 0.7272
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0104 0.0104
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0181 0.0147
Brugia malayi protein kinase C II. 0.0422 0.1147 0.1147
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0757 0.2452 0.2452
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0472 0.0439
Brugia malayi Protein kinase domain containing protein 0.0135 0.0033 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Echinococcus multilocularis netrin receptor unc 5 0.0216 0.0345 0.0345
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Echinococcus granulosus hypothetical protein 0.0249 0.0475 0.0475
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0246 0.0463 0.0429
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0317 0.0738 0.0738
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0472 0.0439
Giardia lamblia Kinase, NEK 0.0282 0.0602 0.1434
Onchocerca volvulus 0.0135 0.0033 0.0055
Entamoeba histolytica hypothetical protein 0.0396 0.1047 0.344
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.2338 0.2338
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0033 0.0033
Echinococcus granulosus neurogenic locus notch protein 4 0.0273 0.0567 0.0567
Entamoeba histolytica protein kinase, putative 0.0588 0.1793 0.595
Schistosoma mansoni myosin-binding protein-related 0.0151 0.0094 0.0094
Echinococcus granulosus raf serine:threonine protein kinase 0.0153 0.0104 0.0104
Echinococcus granulosus dual specificity 0.0287 0.0624 0.0624
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.1395 0.1395
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1505 0.5358 0.5358
Onchocerca volvulus Putative cubilin 0.0273 0.0567 0.1984
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0472 0.0439
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0329 0.0786 0.0754
Echinococcus multilocularis CDC7 cell division cycle 7 0.0186 0.023 0.023
Loa Loa (eye worm) TK protein kinase 0.0257 0.0506 0.0506
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0463 0.0463
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0246 0.0463 0.0463
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0419 0.1135 0.1135
Echinococcus granulosus c src tyrosine kinase 0.0194 0.0261 0.0261
Entamoeba histolytica protein kinase, putative 0.0266 0.0542 0.1738
Loa Loa (eye worm) AGC/PKA protein kinase 0.0234 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0135 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0248 0.0472 0.0439
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0457 0.1282 0.1282
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0248 0.0472 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.112 0.112
Brugia malayi Protein kinase domain containing protein 0.0333 0.0801 0.0801
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Echinococcus granulosus tyrosine protein kinase Blk 0.0257 0.0506 0.0506
Giardia lamblia Kinase, AGC AKT 0.0242 0.0449 0.0918
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Loa Loa (eye worm) TK/INSR protein kinase 0.062 0.1918 0.1918
Plasmodium falciparum glycogen synthase kinase 3 0.0266 0.0542 0.0509
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0186 0.0186
Echinococcus granulosus protein jagged 2 0.0273 0.0567 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0266 0.0542 0.1656
Loa Loa (eye worm) TK/EGFR protein kinase 0.0716 0.2292 0.2292
Loa Loa (eye worm) casein kinase 0.0372 0.0953 0.0953
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus granulosus Immunoglobulin 0.0156 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0375 0.0965 0.0965
Loa Loa (eye worm) TK/EPH protein kinase 0.0235 0.0423 0.0423
Schistosoma mansoni cell adhesion molecule 0.0307 0.07 0.07
Trypanosoma brucei protein kinase, putative 0.0191 0.0248 0.0214
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0624 0.1921
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0472 0.1433
Schistosoma mansoni tyrosine kinase 0.0499 0.1448 0.1448
Brugia malayi Protein kinase domain containing protein 0.0128 0.0006 0.0006
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0324 0.0766 0.0766
Loa Loa (eye worm) hypothetical protein 0.0678 0.2144 0.2144
Brugia malayi Calcium binding EGF domain containing protein 0.0273 0.0567 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Loa Loa (eye worm) hypothetical protein 0.0319 0.0746 0.0746
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0316 0.0734 0.0734
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Brugia malayi STE20-like kinase MST 0.0531 0.157 0.157
Echinococcus granulosus protein kinase c epsilon type 0.0422 0.1147 0.1147
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0404 0.0404
Echinococcus multilocularis expressed protein 0.0172 0.0176 0.0176
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Trichomonas vaginalis AGC family protein kinase 0.0354 0.0884 0.2753
Brugia malayi Immunoglobulin I-set domain containing protein 0.0307 0.07 0.07
Onchocerca volvulus 0.0186 0.023 0.0764
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0266 0.0542 0.0542
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0472 0.0439
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.0425 0.1281
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0472 0.0472
Echinococcus granulosus leucine rich repeat containing protein 4 0.0132 0.0021 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.2699 1 1
Onchocerca volvulus Peroxidasin homolog 0.0133 0.0023 0.0019
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0472 0.0472
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Echinococcus multilocularis Immunoglobulin 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0504 0.1465 0.5225
Trichomonas vaginalis CMGC family protein kinase 0.0186 0.023 0.0655
Onchocerca volvulus 0.0132 0.0021 0.0012
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0827 0.2697
Plasmodium falciparum calcium-dependent protein kinase 1 0.0209 0.0319 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0137 0.0137
Echinococcus granulosus rho-associated protein kinase 1 0.0672 0.2118 0.2118
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567
Onchocerca volvulus 0.0156 0.0115 0.0349
Onchocerca volvulus 0.0135 0.0033 0.0055
Echinococcus granulosus aurora kinase A 0.0243 0.0453 0.0453
Echinococcus granulosus roundabout 2 0.0829 0.2731 0.2731
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0266 0.0542 0.0509
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0175 0.0189 0.0549
Schistosoma mansoni tyrosine kinase 0.0194 0.0261 0.0261
Trichomonas vaginalis AGC family protein kinase 0.0234 0.0416 0.1253
Trichomonas vaginalis CMGC family protein kinase 0.0207 0.0313 0.0921
Schistosoma mansoni basigin related 0.0156 0.0113 0.0113
Toxoplasma gondii selenide, water dikinase 0.0248 0.0472 0.0439
Echinococcus multilocularis roundabout 2 0.0307 0.07 0.07
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0172 0.0176 0.0142
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Echinococcus granulosus casein kinase I gamma 0.0441 0.122 0.122
Echinococcus multilocularis down syndrome cell adhesion 0.0132 0.0021 0.0021
Plasmodium falciparum cGMP-dependent protein kinase 0.0175 0.0186 0.0151
Brugia malayi P38 map kinase family protein 2 0.0329 0.0786 0.0786
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0479 0.1368 0.1368
Loa Loa (eye worm) glutathione reductase 0.2699 1 1
Trypanosoma cruzi casein kinase, putative 0.0225 0.0381 0.0348
Loa Loa (eye worm) cyclin domain-containing protein 0.0885 0.2947 0.2947
Trichomonas vaginalis STE family protein kinase 0.0178 0.02 0.0558
Loa Loa (eye worm) hypothetical protein 0.0504 0.1465 0.1465
Loa Loa (eye worm) SRC-1 0.0316 0.0734 0.0734
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Loa Loa (eye worm) AUR protein kinase 0.0243 0.0453 0.0453
Echinococcus granulosus calcium activated potassium channel 0.0279 0.0591 0.0591
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0316 0.0734 0.0734
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0639 0.1991 0.1991
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0243 0.0453 0.144
Echinococcus multilocularis thioredoxin glutathione reductase 0.2699 1 1
Echinococcus granulosus insulin growth factor binding 0.0132 0.0021 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0319 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.1188 0.4125 0.4125
Brugia malayi Myb-like DNA-binding domain containing protein 0.0132 0.0021 0.0021
Brugia malayi hypothetical protein 0.0459 0.1292 0.1292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0115 0.0115
Echinococcus granulosus Immunoglobulin subtype 0.0156 0.0113 0.0113
Trichomonas vaginalis CK1 family protein kinase 0.0225 0.0381 0.1141
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0472 0.1433
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Plasmodium vivax serine/threonine protein kinase, putative 0.0172 0.0176 0.0017
Brugia malayi serine/threonine-protein kinase 6 0.0243 0.0453 0.0453
Giardia lamblia Kinase, CMGC MAPK 0.0173 0.0181 0.0017
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1678 0.5299
Toxoplasma gondii thioredoxin reductase 0.2699 1 1
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0207 0.0313 0.0156
Echinococcus granulosus c4b binding protein beta chain 0.0504 0.1465 0.1465
Echinococcus granulosus tyrosine protein kinase Src42A 0.0192 0.0253 0.0253
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0243 0.0453 0.0453
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0162 0.0137 0.0103
Onchocerca volvulus Serine\/threonine kinase homolog 0.0339 0.0826 0.2917
Echinococcus multilocularis serine:threonine protein kinase N2 0.06 0.1841 0.1841
Entamoeba histolytica protein kinase, putative 0.0189 0.0241 0.0726
Loa Loa (eye worm) CDC7 protein kinase 0.0186 0.023 0.023
Onchocerca volvulus 0.0248 0.0472 0.1641
Toxoplasma gondii AGC kinase 0.0234 0.0416 0.0383
Giardia lamblia Kinase, NEK 0.0282 0.0602 0.1434
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0175 0.0189 0.0154
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0463 0.1471
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0316 0.0734 0.0734
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0287 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0316 0.0734 0.0734
Leishmania major trypanothione reductase 0.2699 1 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0209 0.0319 0.0319
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0734 0.0734
Onchocerca volvulus Serine\/threonine kinase homolog 0.0558 0.1678 0.5993
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0375 0.0965 0.0965
Schistosoma mansoni vam6/vps39 related 0.0231 0.0404 0.0404
Brugia malayi Fibronectin type III domain containing protein 0.0541 0.1611 0.1611
Echinococcus multilocularis protein tyrosine kinase 0.0595 0.1819 0.1819
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0179 0.0204 0.0045
Trichomonas vaginalis glutathione reductase, putative 0.0935 0.3143 1
Echinococcus multilocularis fibropellin Ia 0.0273 0.0567 0.0567
Toxoplasma gondii rhoptry neck protein RON1 0.0504 0.1465 0.1435
Onchocerca volvulus 0.0266 0.0542 0.1891
Plasmodium falciparum ferrodoxin reductase-like protein 0.0248 0.0472 0.0439
Schistosoma mansoni hypothetical protein 0.021 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0288 0.0627 0.0627
Echinococcus granulosus Protein kinase C brain isozyme 0.0504 0.1465 0.1465
Schistosoma mansoni notch 0.0273 0.0567 0.0567
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Toxoplasma gondii casein kinase I 0.0225 0.0381 0.0348
Loa Loa (eye worm) TK/FAK protein kinase 0.0601 0.1844 0.1844
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0453 0.1372
Entamoeba histolytica protein kinase domain containing protein 0.0266 0.0542 0.1738
Echinococcus multilocularis calcium activated potassium channel 0.0279 0.0591 0.0591
Loa Loa (eye worm) projectin 0.0151 0.0094 0.0094
Brugia malayi Protein kinase domain containing protein 0.04 0.1064 0.1064
Loa Loa (eye worm) hypothetical protein 0.0397 0.1049 0.1049
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0339 0.0827 0.0795
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0472 0.0472
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0307 0.07 0.07
Schistosoma mansoni tyrosine kinase 0.0132 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0132 0.0021 0.0021
Echinococcus multilocularis hypothetical protein 0.021 0.0325 0.0325
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0318 0.0742 0.071
Schistosoma mansoni vesicular amine transporter 0.0522 0.1538 0.1538
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0307 0.07 0.07
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1997 0.7272 0.7272
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0935 0.3143 0.3119
Schistosoma mansoni slit 0.0273 0.0569 0.0569
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0935 0.3143 0.2803
Brugia malayi Hr1 repeat family protein 0.06 0.1841 0.1841
Trichomonas vaginalis STE family protein kinase 0.0175 0.0189 0.0523
Entamoeba histolytica hypothetical protein 0.0253 0.049 0.1564
Echinococcus granulosus tyrosine protein kinase Src42A 0.0316 0.0734 0.0734
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0094 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0021 0.0021
Schistosoma mansoni titin 0.0132 0.0021 0.0021
Schistosoma mansoni basigin related 0.0156 0.0113 0.0113
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0231 0.0404 0.0404
Plasmodium vivax apical sushi protein, putative 0.0504 0.1465 0.1327
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0935 0.3143 0.3143
Leishmania major hypothetical protein, conserved 0.0248 0.0472 0.0439
Giardia lamblia Kinase, CMGC GSK 0.0266 0.0542 0.1232
Echinococcus granulosus dual specificity 0.0287 0.0624 0.0624
Schistosoma mansoni hypothetical protein 0.0156 0.0113 0.0113
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0156 0.0113 0.0113
Echinococcus multilocularis c4b binding protein beta chain 0.0504 0.1465 0.1465
Brugia malayi Cadherin domain containing protein 0.0273 0.0568 0.0568
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0236 0.0425 0.0425
Brugia malayi EGF-like domain containing protein 0.0273 0.0567 0.0567
Schistosoma mansoni tyrosine kinase 0.062 0.1918 0.1918
Loa Loa (eye worm) hypothetical protein 0.0295 0.0653 0.0653
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0742 0.0742
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0021 0.0021
Brugia malayi Animal haem peroxidase family protein 0.0132 0.0021 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0162 0.0137 0.0358
Entamoeba histolytica protein kinase domain containing protein 0.0266 0.0542 0.1738
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0926 0.3108 0.3108
Echinococcus multilocularis neural cadherin 0.0273 0.0568 0.0568
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.1292 0.1292
Echinococcus granulosus casein kinase I alpha 0.0225 0.0381 0.0381
Trichomonas vaginalis AGC family protein kinase 0.0604 0.1854 0.5865
Echinococcus multilocularis expressed conserved protein 0.0175 0.0186 0.0186
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0324 0.0766 0.0734
Schistosoma mansoni tyrosine kinase 0.0355 0.0888 0.0888
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0472 0.1433
Plasmodium falciparum calcium-dependent protein kinase 3 0.0209 0.0319 0.0285
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0181 0.0499
Loa Loa (eye worm) hypothetical protein 0.0156 0.0113 0.0113
Onchocerca volvulus 0.0504 0.1465 0.5225
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0156 0.0113 0.0113
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0288 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0273 0.0567 0.0567

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 115 nM In vitro binding affinity for Dopamine receptor D1 ChEMBL. 15689153
Ki (binding) = 2890 nM In vitro binding affinity for Dopamine receptor D2 ChEMBL. 15689153

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.