Detailed information for compound 312320

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 741.56 | Formula: C22H46N7O15P3
  • H donors: 9 H acceptors: 12 LogP: -8.51 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 4
  • SMILES: O[C@@H]1[C@H](COP(=O)(OP(=O)(OP(=O)(O)[O-])[O-])O)O[C@H]([C@H]1O)n1cnc2c1c(=O)[nH][nH]c(=O)[nH]2.CC[NH+](CC)CC.CC[NH+](CC)CC
  • InChi: 1S/C10H16N5O15P3.2C6H15N/c16-5-3(1-27-32(23,24)30-33(25,26)29-31(20,21)22)28-9(6(5)17)15-2-11-7-4(15)8(18)13-14-10(19)12-7;2*1-4-7(5-2)6-3/h2-3,5-6,9,16-17H,1H2,(H,13,18)(H,23,24)(H,25,26)(H2,12,14,19)(H2,20,21,22);2*4-6H2,1-3H3/t3-,5+,6?,9-;;/m0../s1
  • InChiKey: HEMZXRUKJCLZJP-HESARQTASA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis lachesin 0.0278 0.0738 0.0738
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Echinococcus granulosus tyrosine protein kinase Srms 0.0491 0.1497 0.1497
Brugia malayi Protein kinase domain containing protein 0.0274 0.0722 0.0711
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Echinococcus multilocularis aurora kinase A 0.0144 0.0257 0.0257
Onchocerca volvulus 0.0535 0.1657 1
Brugia malayi casein kinase I 0.0108 0.013 0.0119
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0264 0.0687 0.0676
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0074 0.0074
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0112 0.0145 0.0142
Echinococcus granulosus titin 0.0126 0.0194 0.0194
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0172 0.0359 0.0359
Giardia lamblia Kinase, AGC AKT 0.0116 0.0159 0.0359
Schistosoma mansoni netrin receptor unc5 0.0152 0.0287 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Leishmania major protein kinase, putative 0.0151 0.0285 0.0252
Entamoeba histolytica protein kinase, putative 0.0284 0.076 0.3268
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0145 0.0333
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0113 0.0149 0.0139
Schistosoma mansoni glutamate synthase 0.0264 0.0687 0.0687
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0165 0.0161
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3275
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Brugia malayi Immunoglobulin I-set domain containing protein 0.0293 0.0791 0.0781
Trichomonas vaginalis glutamate synthase, putative 0.0264 0.0687 0.1994
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0119 0.0169 0.0169
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0137 0.0234 0.0201
Onchocerca volvulus 0.0127 0.0199 0.1181
Onchocerca volvulus Putative titin 0.0126 0.0194 0.1152
Schistosoma mansoni protein kinase 0.0189 0.042 0.042
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.0214 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0321 0.0321
Echinococcus multilocularis netrin receptor unc 5 0.018 0.0386 0.0386
Loa Loa (eye worm) hypothetical protein 0.0492 0.1504 0.1495
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Echinococcus multilocularis cyclin 0.0712 0.2287 0.2287
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus granulosus neuropeptide receptor 0.079 0.2567 0.2567
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0655
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0231 0.0569 0.0569
Brugia malayi Protein kinase domain containing protein 0.0084 0.0042 0.0031
Entamoeba histolytica p21-activated kinase 0.0095 0.0083 0.0357
Brugia malayi Thioredoxin reductase 0.2869 1 1
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Brugia malayi glutamate synthase 0.0264 0.0687 0.0676
Brugia malayi basement membrane proteoglycan 0.0152 0.0287 0.0275
Schistosoma mansoni protein kinase 0.0108 0.013 0.013
Echinococcus granulosus rho-associated protein kinase 1 0.0317 0.0875 0.0875
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0092 0.0074 0.0074
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.013 0.0287
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0151 0.0285 0.0252
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Brugia malayi serine/threonine-protein kinase plk-2 0.0264 0.0686 0.0675
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Entamoeba histolytica casein kinase, putative 0.01 0.0101 0.0433
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0293 0.0791 0.0791
Entamoeba histolytica disulphide oxidoreductase, putative 0.0264 0.0687 0.2955
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.0165 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Brugia malayi Protein kinase domain containing protein 0.0151 0.0285 0.0274
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0121 0.0177 0.0143
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0264 0.0687 0.0655
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0264 0.0687 0.0683
Echinococcus granulosus peroxidasin 0.0278 0.0739 0.0739
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0128 0.0128
Mycobacterium ulcerans glutamate synthase subunit beta 0.0264 0.0687 0.1853
Echinococcus granulosus calcium activated potassium channel 0.0133 0.022 0.022
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0521 0.0521
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0219 0.0219
Echinococcus multilocularis rac serine:threonine kinase 0.0163 0.0326 0.0326
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0137 0.0234 0.0224
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.0214 0.0203
Echinococcus granulosus serine:threonine protein kinase N2 0.0125 0.0189 0.0189
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0981 0.325 0.325
Giardia lamblia Kinase, CAMK CAMKL 0.0097 0.0091 0.0151
Toxoplasma gondii histone kinase SNF1, putative 0.009 0.0064 0.003
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0151 0.0285 0.0252
Onchocerca volvulus 0.0126 0.0194 0.1152
Brugia malayi Hr1 repeat family protein 0.029 0.078 0.0769
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0994 0.3298 0.3275
Echinococcus multilocularis tyrosine protein kinase Fgr 0.022 0.0528 0.0528
Echinococcus granulosus tyrosine protein kinase Lyn 0.0255 0.0655 0.0655
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0264 0.0687 0.0687
Schistosoma mansoni protein kinase 0.0421 0.1249 0.1249
Schistosoma mansoni vam6/vps39 related 0.0108 0.0128 0.0128
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0199 0.0453 0.0443
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Echinococcus granulosus serine:threonine protein kinase 3 0.0251 0.064 0.064
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0271 0.0714 0.2076
Echinococcus multilocularis hemicentin 1 0.0278 0.0738 0.0738
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0151 0.0285 0.0281
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0329 0.0918 0.0908
Echinococcus granulosus cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Brugia malayi Protein kinase domain containing protein 0.0581 0.1821 0.1811
Plasmodium falciparum calcium-dependent protein kinase 2 0.0101 0.0103 0.0069
Echinococcus granulosus casein kinase I delta 0.0108 0.013 0.013
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus granulosus Vam6:Vps39 protein 0.0108 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0141 0.0248 0.0238
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0492 0.1504 0.1504
Schistosoma mansoni protein kinase 0.0231 0.0569 0.0569
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0343 0.0969 0.0959
Brugia malayi Sushi domain 0.0535 0.1657 0.1647
Loa Loa (eye worm) hypothetical protein 0.0178 0.0379 0.0368
Echinococcus granulosus mitogen activated protein kinase 11 0.0157 0.0304 0.0304
Entamoeba histolytica hypothetical protein 0.0121 0.0177 0.0761
Echinococcus granulosus serine:threonine protein kinase N2 0.029 0.078 0.078
Echinococcus granulosus Immunoglobulin 0.0492 0.1504 0.1504
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0162 0.0321 0.0321
Plasmodium falciparum calcium-dependent protein kinase 3 0.0101 0.0103 0.0069
Brugia malayi cell division control protein 2 homolog 0.0118 0.0165 0.0154
Schistosoma mansoni tyrosine kinase 0.059 0.1852 0.1852
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0000052153 0.0000052153
Echinococcus granulosus expressed protein 0.0084 0.0042 0.0042
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.023 0.0565 0.0565
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0994 0.3298 1
Echinococcus granulosus c4b binding protein beta chain 0.0535 0.1657 0.1657
Echinococcus multilocularis serine:threonine protein kinase N2 0.0165 0.0334 0.0334
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0077 0.0019 0.0019
Schistosoma mansoni cell adhesion molecule 0.0278 0.0738 0.0738
Schistosoma mansoni nephrin related 0.0126 0.0194 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.0257 0.1105
Onchocerca volvulus 0.0317 0.0875 0.527
Loa Loa (eye worm) hypothetical protein 0.0507 0.1558 0.1549
Echinococcus granulosus thioredoxin glutathione reductase 0.2869 1 1
Echinococcus granulosus leucine rich repeat containing protein 4 0.0126 0.0194 0.0194
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0535 0.1657 0.1648
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0154 0.0295 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Loa Loa (eye worm) hypothetical protein 0.0138 0.0237 0.0227
Echinococcus granulosus lachesin 0.0278 0.0738 0.0738
Echinococcus multilocularis 0.0126 0.0194 0.0194
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0161 0.032 0.031
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Onchocerca volvulus 0.0108 0.0128 0.075
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0112 0.0145 0.0111
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0994 0.3298 0.2803
Echinococcus granulosus casein kinase I alpha 0.0108 0.013 0.013
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0994 0.3298 1
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0077 0.0019 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0116 0.0159 0.0148
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0151 0.0285 0.0281
Schistosoma mansoni kinase 0.0281 0.075 0.075
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0389 0.1136 0.1136
Brugia malayi Immunoglobulin I-set domain containing protein 0.0363 0.1041 0.103
Schistosoma mansoni hypothetical protein 0.0108 0.0128 0.0128
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Schistosoma mansoni growth factor receptor-bound protein 0.0089 0.0061 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.049 0.049
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0287 0.0275
Loa Loa (eye worm) disorganized muscle protein 1 0.0126 0.0194 0.0184
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Entamoeba histolytica hypothetical protein 0.0366 0.1051 0.4521
Schistosoma mansoni tyrosine kinase 0.0343 0.0971 0.0971
Trypanosoma cruzi hypothetical protein, conserved 0.0264 0.0687 0.0683
Loa Loa (eye worm) hypothetical protein 0.0771 0.2498 0.249
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Brugia malayi Protein kinase domain containing protein 0.0343 0.0969 0.0959
Echinococcus granulosus protein kinase shaggy 0.0127 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0108 0.0128 0.0117
Leishmania major protein kinase, putative 0.0151 0.0285 0.0252
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Echinococcus granulosus casein kinase I alpha 0.0108 0.013 0.013
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0145 0.0111
Echinococcus multilocularis protein jagged 2 0.029 0.078 0.078
Giardia lamblia Kinase, NEK 0.0135 0.0225 0.0561
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.009 0.0064 0.003
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Echinococcus multilocularis cyclin dependent kinase 19 0.0942 0.3111 0.3111
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0151 0.0283 0.0273
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0108 0.0128 0.0117
Entamoeba histolytica casein kinase 1, putative 0.0108 0.013 0.056
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0127 0.0199 0.0195
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0182 0.0396 0.0384
Echinococcus granulosus aurora kinase A 0.0144 0.0257 0.0257
Echinococcus multilocularis dual specificity 0.0121 0.0177 0.0177
Brugia malayi P38 map kinase family protein 2 0.0157 0.0304 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0157 0.0304 0.0294
Loa Loa (eye worm) cyclin domain-containing protein 0.0712 0.2287 0.2279
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Schistosoma mansoni tyrosine kinase 0.0389 0.1136 0.1135
Schistosoma mansoni protein kinase 0.0259 0.0668 0.0668
Schistosoma mansoni basigin related 0.0152 0.0287 0.0287
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0114 0.0152 0.0152
Echinococcus multilocularis expressed conserved protein 0.0133 0.0219 0.0219
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0112 0.0145 0.0111
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus granulosus titin 0.0177 0.0375 0.0375
Echinococcus granulosus titin 0.0126 0.0194 0.0194
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3275
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0375 0.0375
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.009 0.0064 0.003
Echinococcus granulosus insulin receptor 0.0433 0.1292 0.1292
Brugia malayi Protein kinase domain containing protein 0.0165 0.0334 0.0323
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0246 0.0623 0.0623
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0479 0.1457 0.1457
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0154 0.0295 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0686 0.0686
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Brugia malayi SH2 domain containing protein 0.039 0.1138 0.1128
Loa Loa (eye worm) hypothetical protein 0.0278 0.0739 0.0729
Loa Loa (eye worm) one IG domain family member 0.0126 0.0194 0.0184
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0101 0.0103 0.0068
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0157 0.0304 0.027
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0357 0.1018 0.1018
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0151 0.0285 0.0252
Brugia malayi Prion-like- 0.0126 0.0194 0.0183
Brugia malayi Kinase associated domain 1 family protein 0.0098 0.0094 0.0082
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0197 0.0447 0.0437
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0145 0.0134
Brugia malayi Furin-like cysteine rich region family protein 0.059 0.1852 0.1842
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0165 0.0165
Echinococcus multilocularis casein kinase I alpha 0.0108 0.013 0.013
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Echinococcus multilocularis epidermal growth factor receptor 0.0389 0.1136 0.1136
Brugia malayi Protein kinase domain containing protein 0.0435 0.1299 0.1289
Loa Loa (eye worm) hypothetical protein 0.0134 0.0221 0.021
Brugia malayi protein unc-22 0.0177 0.0375 0.0363
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0227 0.0555 0.0545
Entamoeba histolytica protein kinase, putative 0.0121 0.0177 0.0761
Onchocerca volvulus 0.0134 0.0221 0.1313
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0264 0.0687 0.1853
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0264 0.0687 0.0687
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0135 0.0225 0.019
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0121 0.0177 0.0173
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0264 0.0687 0.0687
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0126 0.0194 0.0194
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0994 0.3298 0.3275
Echinococcus granulosus tyrosine kinase 0.0183 0.0397 0.0397
Schistosoma mansoni tyrosine kinase 0.0433 0.1292 0.1292
Echinococcus multilocularis C type lectin domian containing protein 0.0535 0.1657 0.1657
Loa Loa (eye worm) programmed cell death 8 0.0264 0.0687 0.0677
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0152 0.0355
Echinococcus multilocularis cyclin dependent kinase 9 0.0079 0.0026 0.0026
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0217 0.0521 0.0521
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0151 0.0285 0.0281
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Echinococcus granulosus neurogenic locus notch protein 4 0.029 0.078 0.078
Echinococcus granulosus neural cadherin 0.029 0.078 0.078
Trypanosoma brucei trypanothione reductase 0.2869 1 1
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0197 0.0447 0.0447
Schistosoma mansoni serine/threonine protein kinase 0.0383 0.1113 0.1112
Plasmodium falciparum glycogen synthase kinase 3 0.0127 0.0199 0.0165
Echinococcus multilocularis rho associated protein kinase 0.0317 0.0875 0.0875
Schistosoma mansoni cell adhesion molecule 0.0126 0.0194 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.0212 0.0503 0.143
Echinococcus granulosus protein tyrosine kinase 0.0533 0.1649 0.1649
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0092 0.0074 0.0074
Onchocerca volvulus 0.0074 0.0008 0.0025
Echinococcus multilocularis tyrosine protein kinase Src42A 0.022 0.0528 0.0528
Brugia malayi SRC-1 0.022 0.0528 0.0517
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0065 0.0087
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0343 0.0969 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Trichomonas vaginalis STE family protein kinase 0.0135 0.0225 0.0577
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0264 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.009 0.0064 0.0053
Brugia malayi Cyclin, N-terminal domain containing protein 0.0712 0.2287 0.2278
Echinococcus multilocularis Immunoglobulin subtype 0.0152 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0114 0.0153 0.0142
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0137 0.0234 0.0231
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.0165 0.0131
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0044 0.001
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Loa Loa (eye worm) TK/FER protein kinase 0.039 0.1138 0.1129
Echinococcus multilocularis raf serine:threonine protein kinase 0.0086 0.0052 0.0052
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0165 0.0161
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis protein jagged 1 0.029 0.078 0.078
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0151 0.0285 0.0281
Schistosoma mansoni hemicentin 0.0141 0.0248 0.0248
Echinococcus granulosus epidermal growth factor receptor 0.0389 0.1136 0.1136
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0683
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.0304 0.0304
Schistosoma mansoni titin 0.0141 0.0248 0.0248
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0435 0.1299 0.129
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.029 0.078 0.078
Mycobacterium tuberculosis Probable oxidoreductase 0.0994 0.3298 0.2803
Onchocerca volvulus 0.0126 0.0194 0.1152
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0191 0.0474
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0187 0.0176
Loa Loa (eye worm) thioredoxin reductase 0.2869 1 1
Loa Loa (eye worm) Notch2 0.029 0.078 0.077
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0264 0.0687 0.0654
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0189 0.042 0.041
Plasmodium falciparum ferrodoxin reductase-like protein 0.0264 0.0687 0.0655
Onchocerca volvulus Peroxidasin homolog 0.0126 0.0194 0.1152
Echinococcus multilocularis cyclin dependent kinase 9 0.0087 0.0054 0.0054
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0000052153 0.0000052153
Onchocerca volvulus 0.0126 0.0194 0.1152
Schistosoma mansoni hypothetical protein 0.0141 0.0248 0.0248
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0343 0.0969 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.1397 0.1397
Echinococcus multilocularis twitchin 0.0161 0.0321 0.0321
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Brugia malayi Protein kinase domain containing protein 0.0357 0.1018 0.1008
Brugia malayi Leucine Rich Repeat family protein 0.0126 0.0195 0.0184
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0182 0.0396 0.0396
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0288 0.0276
Entamoeba histolytica PH domain containing protein kinase, putative 0.0163 0.0326 0.1402
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0634 0.0634
Brugia malayi pregnancy-associated plasma protein-A 0.0535 0.1657 0.1647
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Trichomonas vaginalis apoptosis inducing factor, putative 0.0264 0.0687 0.1994
Trypanosoma brucei casein kinase I, isoform 2 0.0108 0.013 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0285 0.0285
Echinococcus granulosus tyrosine protein kinase Src42A 0.0139 0.0239 0.0239
Loa Loa (eye worm) AGC/PKA protein kinase 0.0112 0.0145 0.0135
Onchocerca volvulus Slit protein homolog 0.0317 0.0878 0.5289
Echinococcus multilocularis serine:threonine kinase SAD 1 0.009 0.0064 0.0064
Schistosoma mansoni nephrin related 0.0152 0.0287 0.0287
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0144 0.0257 0.1105
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0257 0.0247
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Brugia malayi Protein kinase domain containing protein 0.0277 0.0733 0.0722
Echinococcus multilocularis slit 2 protein 0.0317 0.0878 0.0878
Schistosoma mansoni tyrosine kinase 0.0135 0.0226 0.0226
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0061 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0152 0.0355
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0141 0.0248 0.0238
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0942 0.3111 0.3103
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0264 0.0686 0.0654
Trypanosoma brucei aurora B kinase 0.0144 0.0257 0.0223
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0133 0.0219 0.0186
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0404 0.1128
Toxoplasma gondii aurora kinase 0.0144 0.0257 0.0223
Echinococcus granulosus twitchin 0.0654 0.2081 0.2081
Echinococcus multilocularis neurogenic locus protein delta 0.029 0.078 0.078
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Onchocerca volvulus 0.009 0.0065 0.0372
Echinococcus multilocularis neurogenic locus notch protein 4 0.029 0.078 0.078
Brugia malayi Protein kinase domain containing protein 0.0162 0.0321 0.031
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0246 0.0623 0.0623
Brugia malayi Serine/threonine-protein kinase SULU 0.0217 0.0521 0.051
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Loa Loa (eye worm) TK protein kinase 0.0338 0.0952 0.0942
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0126 0.0194 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus multilocularis insulin receptor 0.0433 0.1292 0.1292
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0098 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0141 0.0248 0.0238
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.0064 0.0275
Brugia malayi Protein kinase domain containing protein 0.0082 0.0037 0.0025
Onchocerca volvulus 0.029 0.078 0.4693
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0213 0.0505 0.0494
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0121 0.0177 0.0143
Brugia malayi GCC2 and GCC3 family protein 0.0825 0.2693 0.2685
Trypanosoma brucei protein kinase, putative 0.0092 0.0072 0.0038
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0994 0.3298 1
Schistosoma mansoni protein kinase 0.0421 0.1249 0.1249
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Schistosoma mansoni microtubule-associated protein tau 0.0761 0.2463 0.2463
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Echinococcus granulosus raf serine:threonine protein kinase 0.0086 0.0052 0.0052
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0097 0.0091 0.0056
Schistosoma mansoni nephrin 0.0293 0.0791 0.0791
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0108 0.0128 0.0128
Echinococcus multilocularis microtubule associated protein 2 0.0761 0.2463 0.2463
Schistosoma mansoni tyrosine kinase 0.0324 0.0902 0.0902
Brugia malayi EGF-like domain containing protein 0.0317 0.0878 0.0867
Plasmodium vivax serine/threonine kinase-1, putative 0.0151 0.0285 0.0251
Brugia malayi probable protein kinase 0.0259 0.0668 0.0657
Echinococcus multilocularis serine:threonine protein kinase 38 0.0165 0.0334 0.0334
Onchocerca volvulus 0.0126 0.0194 0.1152
Echinococcus multilocularis hypothetical protein 0.0098 0.0094 0.0094
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0088 0.0056 0.0242
Schistosoma mansoni roundabout 0.0278 0.0738 0.0738
Entamoeba histolytica protein kinase domain containing protein 0.0121 0.0177 0.0761
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0108 0.0128 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0048 0.0044
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0084 0.0042 0.0008
Giardia lamblia Kinase, CMGC CK2 0.01 0.0101 0.018
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0084 0.0042 0.0032
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0157 0.0304 0.027
Echinococcus multilocularis peroxidasin 0.0278 0.0739 0.0739
Trypanosoma cruzi casein kinase II, putative 0.01 0.0101 0.0097
Echinococcus granulosus cyclin dependent kinase 9 0.0087 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0336 0.0945 0.0935
Brugia malayi map kinase activated protein kinase protein 2 0.0383 0.1113 0.1102
Leishmania major protein kinase, putative 0.0144 0.0257 0.0223
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0287 0.0287
Schistosoma mansoni tyrosine kinase 0.022 0.0528 0.0528
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.013 0.012
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0264 0.0687 0.0655
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.073 0.2354 0.2345
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0994 0.3298 1
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus granulosus protein kinase C gamma type 0.0205 0.0475 0.0475
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.022
Schistosoma mansoni protein kinase 0.0151 0.0283 0.0283
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0044 0.001
Trypanosoma cruzi NADH dehydrogenase, putative 0.0264 0.0687 0.0683
Echinococcus multilocularis neural cadherin 0.029 0.078 0.078
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0048 0.0013
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.004
Onchocerca volvulus 0.0535 0.1657 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0293 0.0791 0.0791
Schistosoma mansoni tyrosine kinase 0.0433 0.1292 0.1292
Loa Loa (eye worm) AGC/PKG protein kinase 0.0133 0.0219 0.0209
Brugia malayi Variant SH3 domain containing protein 0.0089 0.0061 0.005
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.022 0.0528 0.0528
Giardia lamblia Kinase, AGC PKA 0.0154 0.0295 0.0777
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Plasmodium falciparum thioredoxin reductase 0.0994 0.3298 0.3275
Loa Loa (eye worm) hypothetical protein 0.0493 0.1505 0.1496
Brugia malayi p70 ribosomal S6 kinase beta 0.0284 0.076 0.0749
Schistosoma mansoni laminin gamma-3 chain 0.029 0.078 0.078
Echinococcus multilocularis fat cadherin tumor suppressor 0.029 0.078 0.078
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0994 0.3298 0.3275
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.0165 0.0155
Schistosoma mansoni peroxidasin 0.0152 0.0288 0.0288
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0101 0.0103 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0453 0.0453
Brugia malayi Protein kinase domain containing protein 0.0581 0.1821 0.1811
Brugia malayi serine/threonine-protein kinase 6 0.0144 0.0257 0.0246
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0101 0.0103 0.0069
Echinococcus multilocularis titin 0.0177 0.0375 0.0375
Schistosoma mansoni rap gtpase-activating protein 0.0108 0.0128 0.0128
Plasmodium vivax thioredoxin reductase, putative 0.2869 1 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0264 0.0686 0.4128
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0264 0.0687 0.0687
Brugia malayi Protein kinase domain containing protein 0.0197 0.0447 0.0436
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0165 0.071
Echinococcus granulosus fibropellin Ia 0.029 0.078 0.078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0771 0.2498 0.249
Entamoeba histolytica cyclin C, putative 0.0722 0.2324 1
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0197 0.0447 0.0447
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0127 0.0199 0.0199
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0177 0.0375 0.0364
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.015 0.0278 0.074
Toxoplasma gondii AGC kinase 0.0284 0.076 0.0728
Echinococcus granulosus low density lipoprotein receptor ldl 0.0152 0.0287 0.0287
Entamoeba histolytica protein kinase, putative 0.0084 0.0042 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0219 0.0219
Echinococcus multilocularis tyrosine kinase 0.0098 0.0094 0.0094
Echinococcus multilocularis casein kinase I delta 0.0108 0.013 0.013
Brugia malayi Stress-activated protein kinase jnk-1 0.0258 0.0665 0.0655
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Loa Loa (eye worm) animal heme peroxidase 0.0126 0.0194 0.0184
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0183 0.0397 0.0397
Brugia malayi Protein kinase domain containing protein 0.0189 0.042 0.0409
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0287 0.0287
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0264 0.0687 0.0676
Brugia malayi Protein kinase domain containing protein 0.0212 0.0503 0.0492
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0167 0.034 0.033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0278 0.0738 0.0728
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0293 0.0791 0.0791
Echinococcus granulosus serine/threonine protein kinase 0.0163 0.0326 0.0326
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0234 0.1009
Brugia malayi Prion-like- 0.0278 0.0738 0.0727
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0264 0.0687 0.2955
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0034 0.0147
Mycobacterium ulcerans hypothetical protein 0.0264 0.0687 0.1853
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0278 0.0738 0.0728
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0082 0.0037 0.0037
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.0165 0.0165
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Trypanosoma cruzi polo-like protein kinase, putative 0.0264 0.0686 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0969 0.0969
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0994 0.3298 0.2803
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0152 0.0287 0.0287
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0991 0.3286 0.3279
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0167 0.034 0.034
Giardia lamblia Kinase, CK1 Casein kinase 0.0108 0.013 0.027
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Onchocerca volvulus 0.0535 0.1657 1
Echinococcus multilocularis G protein coupled receptor 139 0.079 0.2567 0.2567
Entamoeba histolytica casein kinase, putative 0.0108 0.013 0.056
Brugia malayi Temporarily assigned gene name protein 59 0.0108 0.0128 0.0116
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0237 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Loa Loa (eye worm) LAD-2 short isoform 0.0152 0.0287 0.0276
Entamoeba histolytica protein kinase, putative 0.0131 0.021 0.0905
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0655
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Schistosoma mansoni notch 0.029 0.078 0.078
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0108 0.013 0.012
Mycobacterium ulcerans monoxygenase 0.0264 0.0687 0.1853
Echinococcus granulosus casein kinase i 0.0108 0.013 0.013
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0086 0.0052 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0619 0.0619
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0234
Leishmania major hypothetical protein, conserved 0.0264 0.0687 0.0655
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0293 0.0281
Onchocerca volvulus 0.0264 0.0687 0.4131
Echinococcus multilocularis titin 0.0126 0.0194 0.0194
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Echinococcus granulosus protein jagged 2 0.029 0.078 0.078
Onchocerca volvulus 0.029 0.078 0.4693
Entamoeba histolytica protein kinase, putative 0.0121 0.0177 0.0761
Mycobacterium ulcerans dehydrogenase 0.0264 0.0687 0.1853
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0246 0.0623 0.0614
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0213 0.0505 0.0495
Echinococcus multilocularis roundabout 2 0.0293 0.0791 0.0791
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0137 0.0234 0.0201
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Echinococcus granulosus dual specificity 0.0121 0.0177 0.0177
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0064 0.003
Echinococcus multilocularis down syndrome cell adhesion 0.0126 0.0194 0.0194
Entamoeba histolytica protein kinase, putative 0.0144 0.0257 0.1105
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0127 0.0199 0.0165
Echinococcus multilocularis roundabout 2 0.0293 0.0791 0.0791
Brugia malayi Casein kinase II, alpha chain 0.01 0.0101 0.0089
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0392 0.1143 0.1143
Echinococcus multilocularis N chimaerin 0.0092 0.0074 0.0074
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0165 0.0155
Loa Loa (eye worm) hypothetical protein 0.0101 0.0103 0.0093
Brugia malayi Protein kinase domain containing protein 0.0185 0.0404 0.0393
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0135 0.0226 0.0226
Onchocerca volvulus Peroxidasin homolog 0.0126 0.0195 0.1159
Brugia malayi Cadherin domain containing protein 0.029 0.078 0.0769
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0447 0.0447
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0103 0.0103
Brugia malayi casein kinase 1, delta 0.0108 0.013 0.0119
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0176 0.0757
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0165 0.0394
Echinococcus multilocularis tyrosine protein kinase Abl 0.0135 0.0226 0.0226
Brugia malayi Immunoglobulin I-set domain containing protein 0.0293 0.0791 0.0781
Schistosoma mansoni c4b-binding protein beta chain 0.0535 0.1657 0.1657
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0396 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0145 0.0145
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.0101 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Schistosoma mansoni cell adhesion molecule 0.0152 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0137 0.0235 0.0224
Echinococcus granulosus Immunoglobulin subtype 0.0152 0.0287 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.0165 0.0165
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0165 0.0165
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0044 0.0007
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0357 0.1018 0.1018
Echinococcus granulosus tyrosine protein kinase Src42A 0.022 0.0528 0.0528
Leishmania major protein kinase A catalytic subunit 0.0112 0.0145 0.0111
Trypanosoma cruzi NADH dehydrogenase, putative 0.0264 0.0687 0.0683
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0082 0.0035 0.0001
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0264 0.0687 0.0655
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0144 0.0257 0.1105
Loa Loa (eye worm) hypothetical protein 0.02 0.0459 0.0449
Brugia malayi Protein kinase domain containing protein 0.0184 0.0402 0.0391
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0152 0.0287 0.0287
Toxoplasma gondii EGF family domain-containing protein 0.029 0.078 0.0748
Echinococcus multilocularis NCK adaptor protein 0.0091 0.0068 0.0068
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0284 0.076 0.075
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0264 0.0687 0.198
Echinococcus granulosus cGMP dependent protein kinase 0.0133 0.0219 0.0219
Plasmodium falciparum thioredoxin reductase 0.2869 1 1
Onchocerca volvulus Neurogenic locus notch homolog 0.029 0.078 0.4693
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0112 0.0145 0.0142
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.0304 0.0304
Brugia malayi RhoGAP domain containing protein 0.0092 0.0074 0.0062
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0151 0.0285 0.0275
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0217 0.0521 0.0511
Echinococcus granulosus tyrosine protein kinase 0.0277 0.0733 0.0733
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0126 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.091 0.2997 0.299
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0165 0.0165
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0127 0.0199 0.0165
Brugia malayi Animal haem peroxidase family protein 0.0126 0.0194 0.0183
Schistosoma mansoni septate junction protein 0.0152 0.0287 0.0287
Schistosoma mansoni glutamate synthase 0.0264 0.0687 0.0687
Leishmania major NADH dehydrogenase, putative 0.0264 0.0687 0.0655
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0293 0.0791 0.0782
Brugia malayi kettin 0.0126 0.0194 0.0183
Echinococcus granulosus cyclin dependent kinase 9 0.0079 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0344 0.0974 0.0964
Loa Loa (eye worm) gastrulation defective protein 1 0.0906 0.2984 0.2977
Mycobacterium ulcerans ferredoxin reductase 0.0264 0.0687 0.1853
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0199 0.0498
Echinococcus multilocularis dual specificity protein kinase clk2 0.0151 0.0285 0.0285
Schistosoma mansoni septate junction protein 0.0278 0.0738 0.0738
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Schistosoma mansoni notch 0.029 0.078 0.078
Echinococcus granulosus delta-like protein 1 0.029 0.078 0.078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Schistosoma mansoni protein kinase C mu 0.0213 0.0505 0.0505
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0101 0.0103 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0492 0.1504 0.1495
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0264 0.0687 0.0655
Echinococcus multilocularis activin receptor type 0.0081 0.0034 0.0034
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0101 0.0433
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Toxoplasma gondii selenide, water dikinase 0.0264 0.0687 0.0655
Echinococcus granulosus titin 0.0126 0.0194 0.0194
Brugia malayi Fibronectin type III domain containing protein 0.0507 0.1558 0.1548
Leishmania major casein kinase II, putative 0.01 0.0101 0.0067
Echinococcus granulosus casein kinase I delta 0.0108 0.013 0.013
Schistosoma mansoni tyrosine kinase 0.0076 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Brugia malayi Protein kinase domain containing protein 0.019 0.0423 0.0412
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0034 0.0031
Schistosoma mansoni tyrosine kinase 0.0343 0.0971 0.0971
Echinococcus multilocularis titin 0.0126 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0299 0.0812 0.0802
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0165 0.0334 0.0334
Echinococcus granulosus protein jagged 1 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0249 0.0633 0.0623
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0128 0.0124
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Schistosoma mansoni protein kinase 0.0231 0.0569 0.0569
Loa Loa (eye worm) AGC/PKN protein kinase 0.029 0.078 0.077
Echinococcus granulosus protein jagged 2 0.029 0.078 0.078
Schistosoma mansoni nephrin 0.0634 0.2009 0.2009
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0044 0.0041
Echinococcus multilocularis death associated protein kinase 1 0.082 0.2675 0.2675
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0264 0.0687 0.1994
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0044 0.001
Loa Loa (eye worm) hypothetical protein 0.0083 0.0039 0.0028
Echinococcus multilocularis epidermal growth factor receptor 0.059 0.1852 0.1852
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0082 0.0037 0.0037
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0183 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0344 0.0974 0.0964
Schistosoma mansoni tyrosine kinase 0.0135 0.0226 0.0226
Echinococcus granulosus microtubule associated protein 2 0.0761 0.2463 0.2463
Brugia malayi Protein kinase domain containing protein 0.0121 0.0177 0.0165
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0126 0.0194 0.0194
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0128 0.0094
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0152 0.0287 0.0287
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.0101 0.0101
Loa Loa (eye worm) AGC/NDR protein kinase 0.0165 0.0334 0.0324
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0264 0.0687 0.0654
Echinococcus multilocularis nervana 2 0.0119 0.0169 0.0169
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0581 0.1821 0.1812
Schistosoma mansoni tyrosine kinase 0.0237 0.059 0.059
Onchocerca volvulus 0.0098 0.0094 0.0549
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0257 0.0247
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0044 0.0044
Echinococcus granulosus Immunoglobulin 0.0152 0.0287 0.0287
Onchocerca volvulus 0.0098 0.0094 0.0549
Onchocerca volvulus 0.0108 0.013 0.0765
Brugia malayi Immunoglobulin I-set domain containing protein 0.0991 0.3286 0.3278
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0165 0.0377
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0479 0.1457 0.1457
Trypanosoma cruzi trypanothione reductase, putative 0.0994 0.3298 0.3295
Schistosoma mansoni tyrosine kinase 0.0389 0.1136 0.1135
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0065 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0145 0.0145
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0044 0.0041
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0119 0.0169 0.0169
Brugia malayi Peroxidasin 0.0278 0.0739 0.0728
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0154 0.0295 0.0262
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0492 0.1504 0.1504
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus multilocularis calcium activated potassium channel 0.0133 0.022 0.022
Trichomonas vaginalis glutathione reductase, putative 0.0994 0.3298 1
Echinococcus multilocularis casein kinase I delta 0.0108 0.013 0.013
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0042 0.0042
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0207 0.0482 0.0472
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0421 0.1249 0.1249
Echinococcus granulosus defective proboscis extension response 0.0492 0.1504 0.1504
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0044 0.0044
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3298
Echinococcus granulosus tyrosine protein kinase shark 0.0304 0.0829 0.0829
Echinococcus granulosus roundabout 2 0.0293 0.0791 0.0791
Loa Loa (eye worm) hypothetical protein 0.0113 0.0149 0.0139
Brugia malayi serine/threonine protein kinase 6 0.0144 0.0257 0.0246
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0264 0.0687 0.0655
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0079 0.0026 0.0016
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0112 0.0145 0.0111
Echinococcus multilocularis growth factor receptor bound protein 2 0.0089 0.0061 0.0061
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0293 0.0791 0.0791
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0048 0.0044
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0383 0.1113 0.1113
Plasmodium falciparum cGMP-dependent protein kinase 0.0133 0.0219 0.0186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0321 0.0889 0.088
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0264 0.0687 0.2955
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0264 0.0687 0.2955
Giardia lamblia Kinase, NEK 0.0135 0.0225 0.0561
Loa Loa (eye worm) TK/FAK protein kinase 0.0539 0.167 0.1661
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0499 0.0499
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Schistosoma mansoni vesicular amine transporter 0.0492 0.1504 0.1504
Trypanosoma brucei rac serine-threonine kinase, putative 0.0293 0.079 0.0759
Brugia malayi Myb-like DNA-binding domain containing protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) projectin 0.0141 0.0248 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0565 0.0565
Plasmodium falciparum NIMA related kinase 1 0.0135 0.0225 0.0191
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0212 0.0503 0.0493
Onchocerca volvulus 0.03 0.0818 0.4923
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0152 0.0287 0.0276
Trypanosoma cruzi polo-like protein kinase, putative 0.0264 0.0686 0.0683
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0127 0.0199 0.0199
Echinococcus granulosus Immunoglobulin 0.0152 0.0287 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0092 0.0074 0.0063
Onchocerca volvulus Tyrosine kinase homolog 0.0473 0.1433 0.8646
Loa Loa (eye worm) AGC/AKT protein kinase 0.0293 0.079 0.0781
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0126 0.0194 0.0183
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0101 0.0103 0.0068
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2869 1 1
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0264 0.0687 0.0655
Echinococcus multilocularis titin 0.0126 0.0194 0.0194
Echinococcus multilocularis Immunoglobulin 0.0492 0.1504 0.1504
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0101 0.0103 0.0093
Echinococcus multilocularis neurogenic locus notch protein 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0644 0.2047 0.2039
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.0304 0.0304
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0101 0.0103 0.0069
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Entamoeba histolytica protein kinase, putative 0.0088 0.0056 0.0242
Brugia malayi Protein kinase domain containing protein 0.0293 0.079 0.078
Schistosoma mansoni sulfide quinone reductase 0.0264 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Trichomonas vaginalis glutamate synthase, putative 0.0264 0.0687 0.1994
Giardia lamblia Kinase, PLK 0.0264 0.0686 0.1978
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Onchocerca volvulus 0.029 0.078 0.4693
Loa Loa (eye worm) hypothetical protein 0.0108 0.0128 0.0117
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0343 0.0969 0.096
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0264 0.0687 0.0687
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Leishmania major protein kinase, putative 0.0085 0.0048 0.0013
Trypanosoma brucei polo-like protein kinase 0.0264 0.0686 0.0654
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Loa Loa (eye worm) TK/ABL protein kinase 0.0098 0.0094 0.0084
Echinococcus granulosus hemicentin 1 0.0278 0.0738 0.0738
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0044 0.0044
Trypanosoma cruzi Protein kinase B 0.0163 0.0326 0.0322
Echinococcus granulosus neurogenic locus notch protein 0.029 0.078 0.078
Brugia malayi MH2 domain containing protein 0.0132 0.0214 0.0202
Onchocerca volvulus 0.0098 0.0094 0.0549
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0149 0.0149
Schistosoma mansoni slit 0.0126 0.0195 0.0195
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Brugia malayi Protein kinase domain containing protein 0.0118 0.0165 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Brugia malayi protein-tyrosine kinase 0.0183 0.0397 0.0386
Onchocerca volvulus 0.0141 0.0248 0.1478
Loa Loa (eye worm) hypothetical protein 0.0223 0.0541 0.0531
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0165 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0112 0.0145 0.0135
Leishmania major protein kinase A catalytic subunit isoform 1 0.0112 0.0145 0.0111
Plasmodium vivax apical sushi protein, putative 0.0535 0.1657 0.1628
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0264 0.0687 0.1853
Toxoplasma gondii rhoptry neck protein RON9 0.0535 0.1657 0.1628
Schistosoma mansoni cell adhesion molecule 0.0293 0.0791 0.0791
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Brugia malayi hypothetical protein 0.0108 0.0128 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Schistosoma mansoni growth factor receptor-bound protein 0.0091 0.0068 0.0068
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.0165 0.0131
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Loa Loa (eye worm) AGC/PKA protein kinase 0.0112 0.0145 0.0135
Brugia malayi Prion-like- 0.0126 0.0194 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0042 0.0039
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0234
Loa Loa (eye worm) hypothetical protein 0.0293 0.0791 0.0782
Loa Loa (eye worm) casein kinase 0.0173 0.0363 0.0353
Echinococcus granulosus neurogenic locus notch protein 0.029 0.078 0.078
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Entamoeba histolytica protein kinase, putative 0.0293 0.079 0.34
Echinococcus granulosus neurogenic locus protein delta 0.029 0.078 0.078
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.039 0.1138 0.1138
Loa Loa (eye worm) hypothetical protein 0.0507 0.1558 0.1549
Echinococcus granulosus protein kinase 0.0151 0.0283 0.0283
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0264 0.0687 0.1853
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0176 0.0757
Giardia lamblia Kinase, STE STE20 0.0085 0.0048 0.0016
Brugia malayi protein kinase C3,putative 0.0155 0.0299 0.0288
Echinococcus granulosus epidermal growth factor receptor 0.059 0.1852 0.1852
Trypanosoma cruzi SNF1-related protein kinases, putative 0.009 0.0064 0.006
Entamoeba histolytica protein kinase, putative 0.0074 0.0008 0.0036
Echinococcus multilocularis Immunoglobulin 0.0152 0.0287 0.0287
Plasmodium falciparum glutathione reductase 0.2869 1 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0199 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Echinococcus granulosus casein kinase I gamma 0.0209 0.049 0.049
Brugia malayi notch-like transmembrane receptor 0.029 0.078 0.0769
Schistosoma mansoni protein kinase 0.0086 0.0052 0.0052
Schistosoma mansoni cell adhesion molecule 0.0293 0.0791 0.0791
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0044 0.0034
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0264 0.0687 0.1853
Echinococcus multilocularis 0.0167 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Plasmodium falciparum apical sushi protein 0.0535 0.1657 0.1628
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0287 0.0275
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Onchocerca volvulus 0.0098 0.0094 0.0549
Brugia malayi Cyclin C 0.1427 0.4846 0.484
Echinococcus granulosus insulin growth factor binding 0.0126 0.0194 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Plasmodium falciparum calcium-dependent protein kinase 1 0.0101 0.0103 0.0069
Schistosoma mansoni hypothetical protein 0.0264 0.0687 0.0687
Plasmodium falciparum serine/threonine protein kinase, putative 0.0144 0.0257 0.0223
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.009 0.0064 0.0054
Echinococcus multilocularis neurogenic locus notch protein 0.029 0.078 0.078
Echinococcus granulosus basement membrane specific heparan sulfate 0.0152 0.0287 0.0287
Echinococcus granulosus tyrosine protein kinase Src64B 0.022 0.0528 0.0528
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0154 0.0295 0.0295
Echinococcus multilocularis casein kinase I alpha 0.0108 0.013 0.013
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0199 0.0482
Echinococcus granulosus mitogen activated protein kinase 14 0.0157 0.0304 0.0304
Schistosoma mansoni hypothetical protein 0.029 0.078 0.078
Brugia malayi Protein kinase domain containing protein 0.009 0.0065 0.0054
Plasmodium vivax casein kinase 1, putative 0.0108 0.013 0.0095
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.022 0.0528 0.0528
Echinococcus multilocularis tyrosine protein kinase shark 0.0304 0.0829 0.0829
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0223 0.0541 0.0541
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0101 0.0103 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Echinococcus granulosus dual specificity protein kinase clk2 0.0151 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0264 0.0687 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0623 0.0623
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.0386 0.0375
Giardia lamblia Kinase, CMGC DYRK 0.0137 0.0234 0.059
Entamoeba histolytica protein kinase, putative 0.0101 0.0103 0.0444
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.0499 0.0499
Toxoplasma gondii AGC kinase 0.0112 0.0145 0.0111
Echinococcus granulosus c src tyrosine kinase 0.0135 0.0226 0.0226
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0086 0.0052 0.0052
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0343 0.0969 0.5841
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.013 0.012
Plasmodium falciparum protein kinase 5 0.0118 0.0165 0.0131
Giardia lamblia Kinase, NEK 0.0135 0.0225 0.0561
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0264 0.0687 0.0683
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0293 0.0791 0.0791
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0234
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Brugia malayi serine/threonine kinase 12 0.0144 0.0257 0.0246
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Schistosoma mansoni slit 0.029 0.0781 0.0781
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0287 0.0275
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0162 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Plasmodium falciparum calcium-dependent protein kinase 5 0.0101 0.0103 0.0069
Loa Loa (eye worm) hypothetical protein 0.0507 0.1558 0.1549
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0112 0.0145 0.0111
Leishmania major protein kinase, putative 0.0101 0.0103 0.0069
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0173 0.0361 0.0351
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0258 0.0665 0.0665
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0089 0.0061 0.0061
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0231 0.0569 0.0569
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.0101 0.0101
Plasmodium vivax serine/threonine protein kinase, putative 0.0084 0.0042 0.0007
Echinococcus multilocularis protein kinase c iota type 0.0285 0.0763 0.0763
Echinococcus granulosus C type lectin domian containing protein 0.0535 0.1657 0.1657
Echinococcus granulosus NDR protein kinase 0.0165 0.0334 0.0334
Echinococcus multilocularis serine threonine protein kinase 0.0205 0.0475 0.0475
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0421 0.1249 0.1249
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0199 0.0453 0.0453
Echinococcus granulosus N chimaerin 0.0092 0.0074 0.0074
Onchocerca volvulus 0.0098 0.0094 0.0549
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Brugia malayi hypothetical protein 0.0535 0.1657 0.1647
Onchocerca volvulus 0.0177 0.0375 0.2243
Brugia malayi basement membrane proteoglycan precursor 0.0152 0.0287 0.0275
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.0165 0.0165
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0278 0.0738 0.4439
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3275
Brugia malayi Calcium binding EGF domain containing protein 0.029 0.078 0.0769
Echinococcus granulosus fibroblast growth factor receptor 4 0.0237 0.059 0.059
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0334 0.0334
Echinococcus granulosus Glutaredoxin protein 5 0.0119 0.0169 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Onchocerca volvulus Serine\/threonine kinase homolog 0.0162 0.0321 0.1918
Loa Loa (eye worm) notch protein 0.029 0.078 0.077
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0257 0.0247
Echinococcus granulosus cGMP dependent protein kinase 1 0.0133 0.0219 0.0219
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0258 0.0665 0.0656
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0234
Schistosoma mansoni cell adhesion molecule 0.0152 0.0287 0.0287
Echinococcus granulosus cyclin dependent kinase 0.0118 0.0165 0.0165
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0167 0.034 0.034
Trypanosoma cruzi aurora B kinase, putative 0.0144 0.0257 0.0253
Echinococcus granulosus tyrosine protein kinase ABL1 0.0098 0.0094 0.0094
Echinococcus multilocularis Immunoglobulin 0.0492 0.1504 0.1504
Brugia malayi Muscle positioning protein 4 0.029 0.078 0.0769
Trichomonas vaginalis STE family protein kinase 0.0085 0.0048 0.0034
Brugia malayi Sex muscle abnormal protein 5 0.0089 0.0061 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.2869 1 1
Onchocerca volvulus 0.0535 0.1657 1
Echinococcus granulosus tyrosine protein kinase otk 0.0278 0.0738 0.0738
Echinococcus multilocularis casein kinase I alpha 0.0108 0.013 0.013
Echinococcus multilocularis 0.0116 0.0158 0.0158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Entamoeba histolytica protein kinase, putative 0.0082 0.0037 0.0157
Plasmodium vivax protein kinase Crk2 0.0118 0.0165 0.013
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0065 0.0087
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0141 0.0248 0.0238
Loa Loa (eye worm) TK protein kinase 0.0183 0.0397 0.0387
Loa Loa (eye worm) hypothetical protein 0.0098 0.0094 0.0084
Echinococcus multilocularis nervana 2 0.0119 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0231 0.0568 0.0558
Onchocerca volvulus Putative cubilin 0.029 0.078 0.4693
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0135 0.0225 0.0191
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Leishmania major hypothetical protein, conserved 0.0264 0.0687 0.0655
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.022 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0285 0.0285
Brugia malayi Delta serrate ligand family protein 0.029 0.078 0.0769
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0152 0.0287 0.0287
Echinococcus granulosus activin receptor type 0.0081 0.0034 0.0034
Echinococcus granulosus NCK adaptor protein 0.0089 0.0061 0.0061
Leishmania major hypothetical protein, conserved 0.0264 0.0687 0.0655
Echinococcus granulosus glutamate synthase 0.0264 0.0687 0.0687
Loa Loa (eye worm) TK/EPH protein kinase 0.0125 0.0188 0.0178
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0343 0.0969 0.096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0264 0.0687 0.0687
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0217 0.0521 0.0521
Giardia lamblia Glutamate synthase 0.0264 0.0687 0.198
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Toxoplasma gondii casein kinase I 0.0108 0.013 0.0096
Echinococcus multilocularis tyrosine protein kinase HCK 0.0131 0.021 0.021
Onchocerca volvulus 0.0141 0.0248 0.1478
Echinococcus multilocularis thioredoxin glutathione reductase 0.2869 1 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.022 0.0528 0.0528
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0234
Echinococcus multilocularis protein tyrosine kinase 0.0533 0.1649 0.1649
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0264 0.0687 0.2955
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0052 0.0052
Schistosoma mansoni septate junction protein 0.029 0.078 0.078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0048 0.0204
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus granulosus nephrin 0.0141 0.0248 0.0248
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Giardia lamblia Kinase, CMGC CLK 0.0151 0.0285 0.0745
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0101 0.0103 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Plasmodium falciparum calcium-dependent protein kinase 4 0.0101 0.0103 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0026 0.0026
Onchocerca volvulus 0.0126 0.0195 0.1159
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0383 0.1113 0.1113
Entamoeba histolytica protein kinase, putative 0.0086 0.0052 0.0225
Toxoplasma gondii thioredoxin reductase 0.2869 1 1
Echinococcus multilocularis neuroglian 0.0619 0.1955 0.1955
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0172 0.0359 0.0359
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0121 0.0177 0.0167
Leishmania major protein kinase A catalytic subunit isoform 2 0.0112 0.0145 0.0111
Brugia malayi Fes/CIP4 homology domain containing protein 0.011 0.0136 0.0124
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0152 0.0287 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Trypanosoma cruzi casein kinase, putative 0.0108 0.013 0.0126
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0191 0.0474
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.022
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.0101 0.0066
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.029 0.078 0.0769
Echinococcus multilocularis tyrosine protein kinase 0.0277 0.0733 0.0733
Brugia malayi Protein kinase domain containing protein 0.0113 0.0149 0.0137
Giardia lamblia High cysteine protein 0.029 0.078 0.2265
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Brugia malayi Protein kinase c protein 2 0.0115 0.0154 0.0143
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0644 0.2047 0.2047
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0264 0.0687 0.0687
Entamoeba histolytica protein kinase, putative 0.0102 0.0108 0.0463
Entamoeba histolytica protein kinase, putative 0.0127 0.0199 0.0856
Loa Loa (eye worm) glutathione reductase 0.2869 1 1
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0251 0.064 0.063
Echinococcus granulosus neuroglian 0.0293 0.0791 0.0791
Entamoeba histolytica cell division protein kinase 2, putative 0.0126 0.0192 0.0828
Loa Loa (eye worm) protein kinase domain-containing protein 0.0209 0.049 0.048
Echinococcus granulosus netrin receptor unc 5 0.018 0.0386 0.0386
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0165 0.0334 0.0334
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0287 0.0275
Schistosoma mansoni neuroglian 0.0293 0.0791 0.0791
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0137 0.0234 0.0201
Schistosoma mansoni serine/threonine kinase 0.0165 0.0334 0.0334
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0199 0.0189
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0044 0.001
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0448 0.1346 0.1346
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.022 0.0528 0.0528
Echinococcus multilocularis fibropellin Ia 0.029 0.078 0.078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0264 0.0687 0.0683
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0144 0.0257 0.0223
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0686 0.1992
Brugia malayi MAP kinase sur-1 0.0084 0.0044 0.0033
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0092 0.0074 0.0074
Echinococcus multilocularis neurogenic locus protein delta 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0278 0.0738 0.0728
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.013 0.0287
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.0165 0.0131
Brugia malayi Protein kinase domain containing protein 0.0433 0.1292 0.1282
Entamoeba histolytica protein kinase, putative 0.0293 0.079 0.34
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0141 0.0248 0.0238
Echinococcus multilocularis Glutaredoxin protein 5 0.0119 0.0169 0.0169
Echinococcus granulosus tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Entamoeba histolytica serine/threonine protein kinase, putative 0.0264 0.0686 0.2952
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0144 0.0257 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0147 0.0147
Schistosoma mansoni protein kinase 0.0144 0.0257 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0134 0.0221 0.021
Leishmania major trypanothione reductase 0.2869 1 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0264 0.0687 0.2955
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.023 0.0565 0.0565
Schistosoma mansoni neuropeptide receptor 0.079 0.2567 0.2567
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0165 0.0394
Schistosoma mansoni glutamate synthase 0.0264 0.0687 0.0687
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0126 0.0194 0.0194
Loa Loa (eye worm) TK/INSR protein kinase 0.0433 0.1292 0.1283
Loa Loa (eye worm) TK protein kinase 0.0131 0.021 0.02
Schistosoma mansoni tyrosine kinase 0.0343 0.0971 0.0971
Onchocerca volvulus 0.029 0.078 0.4693
Schistosoma mansoni tyrosine kinase 0.0357 0.1019 0.1019
Brugia malayi hypothetical protein 0.0507 0.1558 0.1548
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0264 0.0687 0.0676
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0264 0.0687 0.1853
Onchocerca volvulus 0.0137 0.0235 0.1397
Brugia malayi C1-like domain containing protein 0.0213 0.0505 0.0494
Echinococcus multilocularis neuroglian 0.0293 0.0791 0.0791
Brugia malayi hypothetical protein 0.0217 0.0521 0.051
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0334 0.0334
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.073 0.2354 0.2345
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0101 0.0103 0.0092
Loa Loa (eye worm) hypothetical protein 0.0089 0.0061 0.0051
Plasmodium falciparum serine/threonine protein kinase 0.0084 0.0042 0.0008
Toxoplasma gondii AGC kinase 0.0112 0.0145 0.0111
Schistosoma mansoni notch 0.029 0.078 0.078
Schistosoma mansoni netrin receptor unc5 0.018 0.0386 0.0386
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0492 0.1504 0.1504
Brugia malayi Prion-like- 0.0126 0.0194 0.0183
Loa Loa (eye worm) hypothetical protein 0.0186 0.0409 0.0399
Brugia malayi SH2 domain containing protein 0.0098 0.0094 0.0083
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Onchocerca volvulus 0.0281 0.0748 0.4505
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0285 0.0761
Trypanosoma brucei hypothetical protein, conserved 0.0264 0.0687 0.0655
Loa Loa (eye worm) thyroid receptor interactor 0.011 0.0136 0.0125
Plasmodium vivax unspecified product 0.01 0.0101 0.0066
Brugia malayi STE20-like kinase MST 0.0251 0.064 0.0629
Brugia malayi Calcium binding EGF domain containing protein 0.029 0.078 0.0769
Echinococcus multilocularis casein kinase I gamma 0.0209 0.049 0.049
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0994 0.3298 0.3274
Loa Loa (eye worm) cyclin C 0.1427 0.4846 0.484
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0994 0.3298 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0112 0.0145 0.0142
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0448 0.1346 0.1346
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0321 0.0889 0.0879
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0264 0.0687 0.1994
Plasmodium falciparum serine/threonine protein kinase KIN 0.009 0.0064 0.003
Schistosoma mansoni disulfide oxidoreductase 0.0264 0.0687 0.0687
Echinococcus granulosus serine threonine protein kinase nrc 0.0154 0.0295 0.0295
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0293 0.0791 0.0791
Brugia malayi Protein kinase domain containing protein 0.0942 0.3111 0.3103
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Schistosoma mansoni protein kinase 0.0086 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0086 0.005 0.004
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.0101 0.0067
Trypanosoma brucei protein kinase, putative 0.0127 0.0199 0.0165
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0165 0.0334 0.0334
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0237 0.059 0.059
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0098 0.0094 0.0406
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Onchocerca volvulus Netrin receptor homolog 0.0154 0.0294 0.1754
Echinococcus multilocularis 0.0151 0.0283 0.0283
Echinococcus multilocularis Immunoglobulin 0.0152 0.0287 0.0287
Echinococcus multilocularis protein kinase shaggy 0.0127 0.0199 0.0199
Brugia malayi Immunoglobulin I-set domain containing protein 0.0167 0.034 0.0329
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0264 0.0686 0.0686
Giardia lamblia Kinase, CAMK CAMKL 0.0097 0.0091 0.0151
Schistosoma mansoni serine/threonine-protein kinase 0.0163 0.0326 0.0326
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0712 0.2287 0.2287
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Trichomonas vaginalis mercuric reductase, putative 0.0994 0.3298 1
Trypanosoma brucei SNF1-related protein kinases, putative 0.009 0.0064 0.003
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0034 0.0031
Schistosoma mansoni vav2 0.0101 0.0105 0.0105
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0112 0.0145 0.0111
Echinococcus granulosus c-Jun N-terminal kinases 0.0258 0.0665 0.0665
Schistosoma mansoni myosin-binding protein-related 0.0141 0.0248 0.0248
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0165 0.0161
Brugia malayi protein kinase C II. 0.0207 0.0482 0.0471
Trypanosoma brucei NADH dehydrogenase 0.0264 0.0687 0.0655
Onchocerca volvulus 0.0178 0.0379 0.2267
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0044 0.0041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0293 0.0791 0.0781
Plasmodium falciparum casein kinase 1 0.0108 0.013 0.0096
Echinococcus granulosus Protein kinase C brain isozyme 0.0245 0.0619 0.0619
Echinococcus granulosus protein kinase c epsilon type 0.0207 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0162 0.0321 0.0311
Schistosoma mansoni ste20-related kinase 0.0201 0.0462 0.0462
Echinococcus granulosus casein kinase I alpha 0.0108 0.013 0.013
Plasmodium falciparum glutathione reductase 0.0994 0.3298 0.3275
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.0101 0.009
Echinococcus multilocularis protein kinase c epsilon type 0.0207 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.0304 0.0304
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0357 0.1018 0.1009
Echinococcus multilocularis c src tyrosine kinase 0.0135 0.0226 0.0226
Schistosoma mansoni notch 0.029 0.078 0.078
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0128 0.0128
Loa Loa (eye worm) TK/EGFR protein kinase 0.059 0.1852 0.1843
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.0304 0.03
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0165 0.0394
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0149 0.0149
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0535 0.1657 0.1648
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0199 0.0856
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0108 0.013 0.0126
Loa Loa (eye worm) SRC-1 0.022 0.0528 0.0518
Schistosoma mansoni serine/threonine-protein kinase 0.0163 0.0326 0.0326
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0264 0.0687 0.0683
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0125 0.019 0.0156
Onchocerca volvulus 0.0126 0.0194 0.1152
Echinococcus multilocularis tyrosine protein kinase Srms 0.0183 0.0397 0.0397
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0149 0.0149
Giardia lamblia Kinase, CDC7 0.009 0.0065 0.007
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0143 0.0255 0.0255
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0101 0.0103 0.0069
Entamoeba histolytica thioredoxin reductase, putative 0.0264 0.0687 0.2955
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0128 0.0128
Schistosoma mansoni serine/threonine kinase 0.022 0.053 0.053
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Schistosoma mansoni protein kinase 0.0081 0.0034 0.0034
Entamoeba histolytica protein kinase, putative 0.0137 0.0234 0.1009
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0264 0.0687 0.0655
Echinococcus multilocularis hemicentin 1 0.0278 0.0738 0.0738
Schistosoma mansoni basigin related 0.0152 0.0287 0.0287
Brugia malayi Egg laying defective protein 4 0.0133 0.0219 0.0208
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0994 0.3298 1
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0143 0.0255 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Entamoeba histolytica protein kinase, putative 0.0144 0.0257 0.1105
Trypanosoma brucei Casein kinase II 0.01 0.0101 0.0067
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.009 0.0064 0.0053
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.0453 0.1951
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Echinococcus multilocularis c4b binding protein beta chain 0.0535 0.1657 0.1657
Loa Loa (eye worm) hypothetical protein 0.0134 0.0221 0.021
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0264 0.0687 0.1994
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0149 0.0149
Echinococcus granulosus contactin 0.0293 0.0791 0.0791
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0065 0.0065
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0264 0.0687 0.0655
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0264 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.0595 0.1872 0.1863
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0264 0.0687 0.0655
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3298
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0182 0.0396 0.0396
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.0482 0.0482
Onchocerca volvulus 0.0186 0.0409 0.2453
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0145 0.0145
Schistosoma mansoni septate junction protein 0.0152 0.0287 0.0287
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0994 0.3298 0.329
Onchocerca volvulus 0.0126 0.0194 0.1152
Echinococcus multilocularis serine:threonine protein kinase 3 0.0251 0.064 0.064
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Onchocerca volvulus 0.0535 0.1657 1
Onchocerca volvulus 0.0535 0.1657 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0274 0.0721 0.0712
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0257 0.0257
Giardia lamblia Kinase, AGC PKA 0.0112 0.0145 0.0316
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0144 0.0257 0.0257
Onchocerca volvulus 0.0126 0.0194 0.1152
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.013 0.013
Schistosoma mansoni titin 0.0278 0.0738 0.0738
Trichomonas vaginalis AGC family protein kinase 0.0135 0.0225 0.0577
Brugia malayi hypothetical protein 0.0098 0.0094 0.0083
Toxoplasma gondii NADPH-glutathione reductase 0.0994 0.3298 0.3275
Giardia lamblia Aurora kinase 0.0144 0.0257 0.0659
Onchocerca volvulus 0.0535 0.1657 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Echinococcus multilocularis neuropeptide receptor 0.079 0.2567 0.2567
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0245 0.0619 0.0619
Plasmodium falciparum protein serine/threonine kinase-1 0.0151 0.0285 0.0252
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0264 0.0687 0.0687
Brugia malayi Immunoglobulin I-set domain containing protein 0.0278 0.0738 0.0727
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.009 0.0064 0.006
Brugia malayi Calcium binding EGF domain containing protein 0.029 0.078 0.0769
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0121 0.0177 0.0173
Loa Loa (eye worm) hypothetical protein 0.0098 0.0094 0.0083
Brugia malayi Disorganized muscle protein 1 0.0126 0.0194 0.0183
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0194 0.0184
Echinococcus granulosus roundabout 2 0.0293 0.0791 0.0791
Trichomonas vaginalis AGC family protein kinase 0.009 0.0064 0.0084
Echinococcus multilocularis notch 0.029 0.078 0.078
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.0254 0.0254
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0264 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.0152 0.0287 0.0276
Loa Loa (eye worm) hypothetical protein 0.0581 0.1821 0.1812
Echinococcus multilocularis tyrosine protein kinase Blk 0.0183 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Echinococcus granulosus tyrosine protein kinase HCK 0.0131 0.021 0.021
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0089 0.0061 0.0051
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0137 0.0234 0.0223
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0287 0.0275
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0264 0.0687 0.0687
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0994 0.3298 0.3275
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0149 0.0275 0.0265
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0581 0.1821 0.1812
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0128 0.0128
Onchocerca volvulus 0.009 0.0065 0.0372
Brugia malayi EGF-like domain containing protein 0.029 0.078 0.0769
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0994 0.3298 0.3298
Entamoeba histolytica protein kinase, putative 0.0165 0.0334 0.1437
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Trichomonas vaginalis AGC family protein kinase 0.0293 0.079 0.2311
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0392 0.1143 0.1143
Onchocerca volvulus 0.0535 0.1657 1
Brugia malayi phosphoinositide-dependent protein kinase I 0.0082 0.0037 0.0025
Schistosoma mansoni protein kinase 0.0357 0.1018 0.1018
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.022
Onchocerca volvulus 0.0535 0.1657 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0994 0.3298 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.022 0.0528 0.0528
Echinococcus multilocularis serine:threonine protein kinase N2 0.0125 0.0189 0.0189
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0174 0.0365 0.0355
Loa Loa (eye worm) hypothetical protein 0.0317 0.0878 0.0868
Schistosoma mansoni serine/threonine protein kinase 0.0258 0.0665 0.0665
Echinococcus granulosus tyrosine kinase 0.0098 0.0094 0.0094
Brugia malayi Heparan sulfate 0.0152 0.0287 0.0275
Brugia malayi Immunoglobulin I-set domain containing protein 0.0507 0.1558 0.1548
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0278 0.0738 0.0738
Giardia lamblia NADH oxidase lateral transfer candidate 0.0994 0.3298 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0091 0.0068 0.0068
Echinococcus granulosus tyrosine protein kinase Blk 0.0183 0.0397 0.0397
Echinococcus granulosus cyclin 0.0712 0.2287 0.2287
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0199 0.0482
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3295
Schistosoma mansoni protein kinase 0.01 0.0101 0.0101
Echinococcus granulosus protein jagged 1 0.029 0.078 0.078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0375 0.0363
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Mycobacterium ulcerans NADH dehydrogenase 0.0264 0.0687 0.1853
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0293 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Echinococcus granulosus neuroglian 0.0619 0.1955 0.1955
Plasmodium vivax glutathione reductase, putative 0.2869 1 1
Onchocerca volvulus 0.0535 0.1657 1
Schistosoma mansoni sulfide quinone reductase 0.0264 0.0687 0.0687
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0264 0.0686 0.0676
Brugia malayi serine/threonine-protein kinase PAK 7 0.0227 0.0555 0.0544
Echinococcus multilocularis myosin iiia 0.0085 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0064 0.0064
Schistosoma mansoni kinase 0.0079 0.0026 0.0026
Brugia malayi Protein kinase domain containing protein 0.0209 0.049 0.0479
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0044 0.0041
Echinococcus granulosus cyclin dependent kinase 19 0.0942 0.3111 0.3111
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0114 0.0152 0.0152
Brugia malayi cyclin-dependent kinase 9 0.0079 0.0026 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0875 0.0875
Schistosoma mansoni tyrosine kinase 0.0304 0.0829 0.0829
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0127 0.0199 0.0199
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0139 0.0239 0.0239
Brugia malayi Protein kinase domain containing protein 0.0539 0.167 0.166
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Echinococcus granulosus nervana 2 0.0119 0.0169 0.0169
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0237 0.059 0.059
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0101 0.0103 0.0093
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Schistosoma mansoni hypothetical protein 0.0098 0.0094 0.0094
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0264 0.0687 0.0655
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0994 0.3298 0.3275
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.0254 0.0254
Plasmodium vivax glycogen synthase kinase 3, putative 0.0127 0.0199 0.0165
Echinococcus multilocularis transfer RNA-Phe 0.0141 0.0248 0.0248
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0185 0.0404 0.0394
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0165 0.0161
Schistosoma mansoni cell adhesion molecule 0.0659 0.2101 0.2101
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0084 0.0042 0.0008
Echinococcus granulosus hypothetical protein 0.0116 0.0158 0.0158
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0994 0.3298 0.3295
Brugia malayi hypothetical protein 0.0152 0.0287 0.0275
Echinococcus multilocularis glutamate synthase 0.0264 0.0687 0.0687
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0126 0.0195 0.0195
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0264 0.0687 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0177 0.0177
Echinococcus multilocularis tyrosine protein kinase Fyn 0.022 0.0528 0.0528
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0199 0.0856
Brugia malayi Cam kinase protein 1 0.0101 0.0103 0.0092
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0044 0.0024
Echinococcus granulosus notch 0.029 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0078 0.0024 0.0013
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0264 0.0687 0.1853
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0994 0.3298 0.3275
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0199 0.0453 0.0442
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0383 0.1113 0.1103
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0234
Echinococcus granulosus slit 2 protein 0.0317 0.0878 0.0878
Plasmodium vivax ferrodoxin reductase, putative 0.0264 0.0687 0.0654
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0264 0.0687 0.1994
Loa Loa (eye worm) hypothetical protein 0.0137 0.0235 0.0224
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0182 0.0396 0.0385
Echinococcus granulosus nervana 2 0.0119 0.0169 0.0169
Echinococcus granulosus serine:threonine kinase SAD 1 0.009 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0234 0.0234
Echinococcus granulosus titin 0.0177 0.0375 0.0375
Schistosoma mansoni hypothetical protein 0.0152 0.0287 0.0287
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0145 0.0145
Echinococcus multilocularis insulin growth factor binding 0.0126 0.0194 0.0194
Entamoeba histolytica protein kinase 2, putative 0.0154 0.0295 0.127
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0264 0.0687 0.0687
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0044 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0101 0.0197
Trichomonas vaginalis AGC family protein kinase 0.0194 0.0435 0.1222
Schistosoma mansoni cell adhesion molecule 0.0141 0.0248 0.0248
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0264 0.0687 0.1994
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Entamoeba histolytica protein kinase, putative 0.0074 0.0008 0.0036
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0165 0.0155
Schistosoma mansoni g1/s-specific cyclin C 0.1427 0.4846 0.4846
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0065 0.0087
Leishmania major casein kinase, putative 0.0108 0.013 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0199 0.0498
Brugia malayi putative serine/threonine kinase SADA gamma 0.009 0.0064 0.0052
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0128 0.0124
Echinococcus multilocularis tyrosine protein kinase otk 0.0278 0.0738 0.0738
Schistosoma mansoni cell polarity protein 0.029 0.078 0.078
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0144 0.0257 0.1105
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0048 0.0204
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0141 0.0248 0.0248
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0278 0.0738 0.0738
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0165 0.0377
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Giardia lamblia Kinase, STE STE20 0.0086 0.0052 0.0031
Onchocerca volvulus Neurogenic locus notch protein homolog 0.029 0.078 0.4693
Schistosoma mansoni hypothetical protein 0.0126 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0098 0.0094 0.0094
Entamoeba histolytica PH domain containing protein kinase, putative 0.0163 0.0326 0.1402
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Brugia malayi Protein kinase domain containing protein 0.091 0.2997 0.2989
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0199 0.0453 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0103 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0565 0.0565
Echinococcus multilocularis serine:threonine protein kinase N2 0.029 0.078 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0942 0.3111 0.3111
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0149 0.0344
Brugia malayi Doublecortin family protein 0.0149 0.0275 0.0264
Schistosoma mansoni titin 0.0177 0.0375 0.0375
Treponema pallidum NADH oxidase 0.0994 0.3298 1
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0052 0.0052
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0264 0.0687 0.0655
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Loa Loa (eye worm) TK/FER protein kinase 0.0098 0.0094 0.0084
Brugia malayi Cadherin domain containing protein 0.029 0.078 0.0769
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0194 0.0183
Giardia lamblia Thioredoxin reductase 0.0264 0.0687 0.198
Echinococcus multilocularis protein jagged 1 0.029 0.078 0.078
Echinococcus multilocularis expressed protein 0.0084 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.029 0.078 0.078
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.0165 0.0165
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.0165 0.0165
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0287 0.0287
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.013 0.0287
Entamoeba histolytica protein kinase, putative 0.0084 0.0042 0.0181
Loa Loa (eye worm) hypothetical protein 0.0116 0.0158 0.0148
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0089 0.0061 0.0051
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0825 0.2693 0.2686
Trichomonas vaginalis STE family protein kinase 0.0086 0.0052 0.0048
Brugia malayi Tyrosine-protein kinase abl-1 0.0135 0.0226 0.0214
Trichomonas vaginalis AGC family protein kinase 0.0173 0.0362 0.0996
Schistosoma mansoni tyrosine kinase 0.0533 0.1649 0.1649
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0064 0.0084
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0126 0.0194 0.0194
Toxoplasma gondii rhoptry neck protein RON1 0.0535 0.1657 0.1628
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0084 0.0042 0.0008
Echinococcus multilocularis casein kinase i 0.0108 0.013 0.013
Schistosoma mansoni notch 0.029 0.078 0.078
Schistosoma mansoni notch 0.029 0.078 0.078
Echinococcus granulosus roundabout 2 0.0786 0.2552 0.2552
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0163 0.0326 0.0322
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0112 0.0145 0.0142
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0264 0.0687 0.1853
Schistosoma mansoni tyrosine kinase 0.022 0.0528 0.0528
Brugia malayi Immunoglobulin I-set domain containing protein 0.0141 0.0248 0.0237
Echinococcus granulosus down syndrome cell adhesion 0.0126 0.0194 0.0194
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0404 0.1128
Brugia malayi intracellular kinase 0.0127 0.0199 0.0188
Echinococcus granulosus tyrosine protein kinase Fps85D 0.039 0.1138 0.1138
Schistosoma mansoni tyrosine kinase 0.0251 0.0642 0.0642
Onchocerca volvulus 0.0098 0.0094 0.0549
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0152 0.0287 0.0287
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0994 0.3298 0.3275
Loa Loa (eye worm) TK/ROR protein kinase 0.0172 0.0359 0.0349
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0712 0.2287 0.2287
Schistosoma mansoni cell adhesion molecule 0.0141 0.0248 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0499 0.0499
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0994 0.3298 0.3295
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.0304 0.03
Schistosoma mansoni nck2/grb4 0.0089 0.0061 0.0061
Loa Loa (eye worm) CAMK protein kinase 0.0177 0.0375 0.0364
Loa Loa (eye worm) TK protein kinase 0.0363 0.1041 0.1031
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0607
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0994 0.3298 0.3275
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0074 0.0062
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0082 0.0037 0.0026
Schistosoma mansoni titin 0.0126 0.0194 0.0194
Entamoeba histolytica protein kinase , putative 0.0144 0.0257 0.1105
Echinococcus granulosus protein kinase c iota type 0.0285 0.0763 0.0763
Onchocerca volvulus 0.029 0.078 0.4693
Loa Loa (eye worm) hypothetical protein 0.029 0.078 0.077
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0257 0.0675
Brugia malayi Protein kinase domain 0.0086 0.0052 0.0041
Schistosoma mansoni septate junction protein 0.0278 0.0738 0.0738
Echinococcus multilocularis roundabout 2 0.0786 0.2552 0.2552
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0082 0.0035 0.0001
Schistosoma mansoni basigin related 0.0152 0.0287 0.0287
Schistosoma mansoni ephrin receptor 0.0108 0.0128 0.0128
Brugia malayi Protein kinase domain containing protein 0.0098 0.0094 0.0083
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0994 0.3298 0.2803
Loa Loa (eye worm) hypothetical protein 0.0444 0.1331 0.1322
Schistosoma mansoni protein kinase 0.0421 0.1249 0.1249
Trypanosoma cruzi hypothetical protein, conserved 0.0264 0.0687 0.0683
Schistosoma mansoni adapter molecule crk 0.0089 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0126 0.0194 0.0184
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.0165 0.0131
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0026 0.0112
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0994 0.3298 0.3274
Schistosoma mansoni atypical protein kinase C 0.0291 0.0784 0.0784
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0321 0.0321
Plasmodium vivax calcium-dependent protein kinase, putative 0.0101 0.0103 0.0068
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0154 0.0295 0.0292
Loa Loa (eye worm) TK protein kinase 0.0277 0.0733 0.0723

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.5 uM Inhibitory concentration against hepatitis C virus helicase ChEMBL. 15633995

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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