Detailed information for compound 312527

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 477.595 | Formula: C28H35N3O4
  • H donors: 0 H acceptors: 0 LogP: 4.38 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2c(cc1OC)OC[C@H]1C2=NO[C@H]1CN1CCN(CC1)CCC/C=C/c1ccccc1
  • InChi: 1S/C28H35N3O4/c1-32-25-17-22-24(18-26(25)33-2)34-20-23-27(35-29-28(22)23)19-31-15-13-30(14-16-31)12-8-4-7-11-21-9-5-3-6-10-21/h3,5-7,9-11,17-18,23,27H,4,8,12-16,19-20H2,1-2H3/b11-7+/t23-,27-/m0/s1
  • InChiKey: PXMMVKVXQSDISZ-YZRSLIQMSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus growth factor receptor bound protein 2 0.0092 0.0091 0.008
Entamoeba histolytica glycogen phosphorylase, putative 0.3262 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0083 0.0076
Plasmodium falciparum calcium-dependent protein kinase 3 0.01 0.0118 0.008
Trypanosoma brucei rac serine-threonine kinase, putative 0.0294 0.0724 0.0879
Onchocerca volvulus 0.0467 0.1266 0.1236
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0144 0.0253 0.0258
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0113 0.0157 0.0157
Echinococcus multilocularis voltage dependent calcium channel 0.019 0.0397 0.039
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0057 0.003
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.0295 0.0288
Brugia malayi basement membrane proteoglycan precursor 0.0135 0.0225 0.0225
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0162 0.0312 0.0311
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0118 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.0452 0.0445
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0223
Onchocerca volvulus 0.0099 0.0114 0.008
Schistosoma mansoni protein kinase 0.0086 0.0073 0.0066
Brugia malayi Prion-like- 0.0113 0.0157 0.0157
Schistosoma mansoni hypothetical protein 0.0113 0.0157 0.0149
Schistosoma mansoni notch 0.0253 0.0596 0.0589
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0202 0.0202
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0148
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0151 0.0278 0.0321
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0344 0.0881 0.0874
Giardia lamblia Kinase, STE STE20 0.0086 0.0073 0.0009
Entamoeba histolytica protein kinase, putative 0.0294 0.0724 0.0717
Echinococcus multilocularis dual specificity protein kinase clk2 0.0151 0.0278 0.0271
Mycobacterium ulcerans monoxygenase 0.023 0.0525 0.1005
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0482 0.1311 0.1305
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus multilocularis hemicentin 1 0.0247 0.0577 0.057
Schistosoma mansoni netrin receptor unc5 0.0135 0.0225 0.0218
Brugia malayi Cadherin domain containing protein 0.0253 0.0596 0.0596
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.023 0.0525 0.0518
Echinococcus granulosus hypothetical protein 0.0117 0.0171 0.016
Onchocerca volvulus Peroxidasin homolog 0.0113 0.0157 0.0123
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0135 0.0225 0.0218
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0625 0.0625
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0247 0.0576 0.0569
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0081 0.0057 0.003
Echinococcus granulosus hemicentin 1 0.0247 0.0577 0.0567
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.023 0.0525 0.0518
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0368 0.0956 0.0946
Brugia malayi Sex muscle abnormal protein 5 0.009 0.0085 0.0085
Echinococcus multilocularis protein jagged 2 0.0253 0.0596 0.0589
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0247 0.0576 0.0566
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0173 0.0182
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0121 0.0183 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0083 0.0076
Echinococcus granulosus expressed protein 0.0083 0.0064 0.0054
Entamoeba histolytica glycogen phosphorylase, putative 0.141 0.4213 0.4209
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0085 0.0083
Echinococcus multilocularis protein kinase c iota type 0.0286 0.07 0.0693
Echinococcus granulosus C type lectin domian containing protein 0.0467 0.1266 0.1256
Loa Loa (eye worm) hypothetical protein 0.0247 0.0577 0.0577
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0226
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.023 0.0525 0.1005
Echinococcus multilocularis Glycosyl transferase, family 35 0.3262 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0234 0.0226
Giardia lamblia Glycogen phosphorylase 0.3262 1 1
Schistosoma mansoni protein kinase 0.0423 0.1128 0.1121
Echinococcus multilocularis growth factor receptor bound protein 2 0.009 0.0085 0.0078
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.012 0.018 0.0172
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0086 0.0073 0.0066
Leishmania major casein kinase, putative 0.0108 0.0142 0.0112
Brugia malayi Doublecortin family protein 0.0149 0.027 0.027
Echinococcus multilocularis ephrin type A receptor 4 A 0.0108 0.0144 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0204 0.0204
Schistosoma mansoni ephrin receptor 0.0108 0.0144 0.0137
Loa Loa (eye worm) one IG domain family member 0.0113 0.0157 0.0156
Echinococcus multilocularis titin 0.0113 0.0157 0.0149
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0137 0.0234 0.0233
Giardia lamblia Kinase, CK1 Casein kinase 0.0108 0.0142 0.0078
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0071 0.0027 0.002
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0173 0.0182
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0135 0.0225 0.0215
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0239 0.0551 0.0544
Echinococcus multilocularis insulin growth factor binding 0.0113 0.0157 0.0149
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.0295 0.0288
Brugia malayi Protein kinase domain containing protein 0.0083 0.0064 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0173 0.0171
Echinococcus granulosus titin 0.0113 0.0157 0.0146
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0682 0.1936 0.1935
Loa Loa (eye worm) calcium channel 0.019 0.0397 0.0397
Plasmodium falciparum cGMP-dependent protein kinase 0.0133 0.022 0.0215
Loa Loa (eye worm) glycogen phosphorylase 0.3262 1 1
Echinococcus granulosus lachesin 0.0247 0.0577 0.0567
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0144 0.0114
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0344 0.0881 0.0881
Schistosoma mansoni hypothetical protein 0.0113 0.0157 0.0149
Loa Loa (eye worm) hypothetical protein 0.0686 0.195 0.195
Loa Loa (eye worm) hypothetical protein 0.0089 0.0081 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0715 0.0708
Schistosoma mansoni hypothetical protein 0.0113 0.0157 0.0149
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Onchocerca volvulus Tyrosine kinase homolog 0.0462 0.1248 0.1218
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.0213
Entamoeba histolytica serine/threonine protein kinase, putative 0.0089 0.0083 0.0076
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0137 0.0234 0.0234
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0189 0.0397 0.0397
Echinococcus granulosus tyrosine kinase 0.0184 0.0381 0.0371
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0347 0.0889 0.0889
Entamoeba histolytica protein kinase domain containing protein 0.0199 0.0427 0.042
Echinococcus multilocularis expressed protein 0.0083 0.0064 0.0057
Echinococcus granulosus tyrosine protein kinase Fyn 0.0221 0.0497 0.0486
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0344 0.0881 0.0881
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.023 0.0525 0.0616
Entamoeba histolytica protein kinase, putative 0.0127 0.0202 0.0195
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0262 0.0625 0.0618
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Echinococcus multilocularis neurogenic locus notch protein 0.0253 0.0596 0.0589
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0202 0.0139
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0089 0.0081 0.0081
Echinococcus granulosus fibroblast growth factor receptor 4 0.0239 0.0551 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Entamoeba histolytica protein kinase , putative 0.0144 0.0253 0.0246
Brugia malayi probable protein kinase 0.0259 0.0615 0.0615
Schistosoma mansoni notch 0.0253 0.0596 0.0589
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.023 0.0525 0.1005
Entamoeba histolytica protein kinase, putative 0.0074 0.0035 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0066 0.0065
Schistosoma mansoni hypothetical protein 0.0135 0.0225 0.0218
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0144 0.0253 0.0246
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Echinococcus granulosus peroxidasin 0.0247 0.0578 0.0568
Schistosoma mansoni nephrin related 0.0113 0.0157 0.0149
Echinococcus multilocularis calcium activated potassium channel 0.0143 0.0252 0.0245
Loa Loa (eye worm) programmed cell death 8 0.023 0.0525 0.0525
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0223
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.0173 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.0881 0.0874
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0116 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0455 0.1225 0.1225
Entamoeba histolytica protein kinase, putative 0.0083 0.0064 0.0057
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0155 0.0148
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0135 0.0225 0.0218
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0385 0.1007 0.0998
Schistosoma mansoni vesicular amine transporter 0.0449 0.1208 0.1202
Brugia malayi SH2 domain containing protein 0.0393 0.1034 0.1034
Brugia malayi Delta serrate ligand family protein 0.0253 0.0596 0.0596
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0247 0.0577 0.057
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0121 0.0183 0.0183
Treponema pallidum NADH oxidase 0.0868 0.2518 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.023 0.0525 0.0464
Echinococcus granulosus Glycosyl transferase family 35 0.3262 1 1
Loa Loa (eye worm) hypothetical protein 0.0247 0.0577 0.0577
Schistosoma mansoni adapter molecule crk 0.009 0.0085 0.0078
Echinococcus granulosus serotonin transporter 0.0089 0.0081 0.0071
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0868 0.2518 1
Schistosoma mansoni protein kinase 0.0189 0.0397 0.039
Trypanosoma cruzi casein kinase, putative 0.0108 0.0142 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0066 0.0059
Mycobacterium ulcerans dehydrogenase 0.023 0.0525 0.1005
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.023 0.0525 0.0518
Brugia malayi Heparan sulfate 0.0135 0.0225 0.0225
Onchocerca volvulus 0.0318 0.0798 0.0767
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.023 0.0525 0.0617
Onchocerca volvulus 0.0253 0.0596 0.0564
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0057 0.005
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.0142 0.014
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.023 0.0525 0.0653
Entamoeba histolytica protein kinase, putative 0.0294 0.0724 0.0717
Entamoeba histolytica protein kinase, putative 0.0101 0.0122 0.0115
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0149 0.027 0.0269
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0127 0.0202 0.0202
Echinococcus multilocularis titin 0.0113 0.0157 0.0149
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0253 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0467 0.046
Onchocerca volvulus 0.0467 0.1266 0.1236
Echinococcus granulosus mitogen activated protein kinase 0.0084 0.0066 0.0056
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0133 0.022 0.0213
Toxoplasma gondii AGC kinase 0.0285 0.0696 0.0879
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0199 0.0427 0.0417
Entamoeba histolytica protein kinase, putative 0.0071 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0059 0.0052
Schistosoma mansoni serine/threonine-protein kinase 0.0163 0.0314 0.0307
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.01 0.0118 0.0118
Schistosoma mansoni titin 0.0247 0.0577 0.057
Schistosoma mansoni protein kinase 0.0232 0.0529 0.0522
Schistosoma mansoni tyrosine kinase 0.036 0.0929 0.0922
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0113 0.0158 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0455 0.1225 0.1225
Echinococcus granulosus tyrosine protein kinase Fyn 0.0221 0.0497 0.0486
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0916 0.2668 0.2668
Plasmodium falciparum glutathione reductase 0.2505 0.7635 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0868 0.2518 0.3248
Trypanosoma brucei Casein kinase II 0.01 0.0116 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0027 0.002
Echinococcus multilocularis casein kinase I alpha 0.0108 0.0142 0.0134
Onchocerca volvulus 0.0188 0.0392 0.0359
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.023 0.0525 0.0515
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0135 0.0225 0.0218
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0108 0.0144 0.0133
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0089 0.0083 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0085 0.0083
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0161 0.0309 0.0309
Schistosoma mansoni tyrosine kinase 0.0346 0.0887 0.088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3268
Toxoplasma gondii casein kinase I 0.0108 0.0142 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0798 0.0791
Onchocerca volvulus 0.0467 0.1266 0.1236
Echinococcus granulosus tyrosine protein kinase HCK 0.0132 0.0216 0.0206
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0154 0.0287 0.0303
Giardia lamblia Kinase, NEK 0.0134 0.0225 0.0162
Onchocerca volvulus 0.0099 0.0114 0.008
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Echinococcus multilocularis neurogenic locus notch protein 0.0253 0.0596 0.0589
Entamoeba histolytica protein kinase 2, putative 0.0154 0.0287 0.028
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0353 0.0908 0.0908
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0085 0.0077
Schistosoma mansoni dihydroorotate dehydrogenase 0.0353 0.0908 0.0901
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0144 0.0144
Echinococcus granulosus notch 0.0253 0.0596 0.0586
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0259 0.0614 0.0613
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0165 0.0322 0.0314
Brugia malayi Protein kinase domain containing protein 0.0682 0.1936 0.1936
Echinococcus granulosus ephrin type A receptor 4 A 0.0108 0.0144 0.0133
Onchocerca volvulus 0.0467 0.1266 0.1236
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0182 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0585 0.0578
Echinococcus granulosus glycogen phosphorylase 0.3262 1 1
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus multilocularis titin 0.0113 0.0157 0.0149
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.023 0.0525 0.1005
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0089 0.0083 0.0034
Entamoeba histolytica hypothetical protein 0.0369 0.0957 0.095
Trypanosoma cruzi hypothetical protein, conserved 0.023 0.0525 0.0646
Plasmodium falciparum casein kinase 2, alpha subunit 0.01 0.0116 0.0077
Brugia malayi Protein kinase domain containing protein 0.0121 0.0183 0.0183
Brugia malayi notch-like transmembrane receptor 0.0253 0.0596 0.0596
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0155 0.0154
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0577 0.0577
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0262 0.0625 0.0615
Echinococcus multilocularis lachesin 0.0247 0.0577 0.057
Loa Loa (eye worm) hypothetical protein 0.0247 0.0578 0.0578
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.01 0.0118 0.0108
Trypanosoma brucei polo-like protein kinase 0.0265 0.0632 0.0758
Loa Loa (eye worm) hypothetical protein 0.0135 0.0225 0.0225
Echinococcus granulosus tyrosine protein kinase Blk 0.0184 0.0381 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.01 0.0116 0.0076
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Loa Loa (eye worm) hypothetical protein 0.0099 0.0114 0.0114
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.023 0.0525 0.0617
Echinococcus granulosus protein tyrosine kinase 0.0537 0.1484 0.1475
Echinococcus multilocularis casein kinase i 0.0108 0.0142 0.0134
Brugia malayi Protein kinase domain containing protein 0.0186 0.0385 0.0385
Entamoeba histolytica protein kinase, putative 0.0137 0.0234 0.0226
Trichomonas vaginalis disulfide oxidoreductase, putative 0.023 0.0525 0.0524
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Echinococcus granulosus leucine rich repeat containing protein 4 0.0113 0.0157 0.0146
Echinococcus granulosus casein kinase I gamma 0.0209 0.0459 0.0449
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Echinococcus granulosus nephrin 0.0128 0.0204 0.0194
Schistosoma mansoni myosin-binding protein-related 0.0128 0.0204 0.0197
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0114 0.0161 0.0154
Loa Loa (eye worm) hypothetical protein 0.0071 0.0028 0.0028
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0113 0.0157 0.0146
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0151 0.0278 0.0291
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0204 0.0204
Echinococcus multilocularis raf serine:threonine protein kinase 0.0087 0.0077 0.0069
Echinococcus granulosus casein kinase I delta 0.0108 0.0142 0.0131
Giardia lamblia Kinase, AGC AKT 0.0116 0.0167 0.0104
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0204 0.0204
Onchocerca volvulus 0.0113 0.0158 0.0124
Echinococcus multilocularis tyrosine kinase 0.0099 0.0114 0.0107
Loa Loa (eye worm) hypothetical protein 0.01 0.0118 0.0118
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0253 0.0253
Brugia malayi Protein kinase domain containing protein 0.0543 0.1502 0.1502
Loa Loa (eye worm) TK protein kinase 0.0351 0.0903 0.0902
Brugia malayi Cyclin, N-terminal domain containing protein 0.0504 0.1379 0.1379
Brugia malayi Protein kinase domain containing protein 0.0438 0.1172 0.1172
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.015 0.0273 0.0266
Brugia malayi serine/threonine-protein kinase plk-2 0.0265 0.0632 0.0632
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0344 0.0881 0.0872
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.019 0.0397 0.0387
Leishmania major protein kinase, putative 0.01 0.0118 0.008
Trypanosoma cruzi polo-like protein kinase, putative 0.0265 0.0632 0.0786
Echinococcus granulosus rho-associated protein kinase 1 0.0318 0.0798 0.0788
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0221 0.0497 0.0486
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Schistosoma mansoni protein kinase 0.0232 0.0529 0.0522
Schistosoma mansoni glycogen phosphorylase 0.3262 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0221 0.0214
Brugia malayi Protein kinase domain containing protein 0.0099 0.0114 0.0114
Trichomonas vaginalis STE family protein kinase 0.0085 0.0069 0.0068
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0151 0.0278 0.0329
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0638 0.1798 0.1798
Brugia malayi ephrin receptor 1 precursor 0.0076 0.0041 0.0041
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0165 0.0322 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0173 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0083 0.0076
Leishmania major NADH dehydrogenase, putative 0.023 0.0525 0.0617
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0118 0.0111
Echinococcus multilocularis glycogen phosphorylase 0.3262 1 1
Loa Loa (eye worm) hypothetical protein 0.0584 0.1631 0.1631
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.031 0.0303
Onchocerca volvulus Serine\/threonine kinase homolog 0.0265 0.0632 0.06
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0625 0.0625
Trypanosoma brucei hypothetical protein, conserved 0.023 0.0525 0.0617
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.019 0.0397 0.039
Loa Loa (eye worm) sex muscle abnormal protein 5 0.009 0.0085 0.0085
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0089 0.0083 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0351 0.0903 0.0903
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0133 0.022 0.0253
Entamoeba histolytica PH domain containing protein kinase, putative 0.0163 0.0314 0.0307
Loa Loa (eye worm) AGC/PKA protein kinase 0.0112 0.0155 0.0155
Brugia malayi RhoGAP domain containing protein 0.0093 0.0096 0.0096
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0614 0.0607
Brugia malayi protein kinase C3,putative 0.0155 0.029 0.029
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.023 0.0525 0.0524
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0253 0.0253
Brugia malayi Peroxidasin 0.0247 0.0578 0.0578
Trypanosoma cruzi casein kinase, putative 0.0108 0.0142 0.0141
Loa Loa (eye worm) hypothetical protein 0.0099 0.0114 0.0113
Plasmodium vivax glycogen synthase kinase 3, putative 0.0127 0.0202 0.0191
Brugia malayi SRC-1 0.0221 0.0497 0.0497
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0427 0.042
Schistosoma mansoni hypothetical protein 0.0108 0.0144 0.0136
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0136 0.023 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0525 0.0518
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0144 0.0136
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0204 0.0204
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.015 0.0273 0.0273
Plasmodium falciparum ferrodoxin reductase-like protein 0.023 0.0525 0.0617
Onchocerca volvulus 0.0113 0.0157 0.0123
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0353 0.0908 0.1921
Trichomonas vaginalis glutamate synthase, putative 0.023 0.0525 0.0524
Trichomonas vaginalis glutamate synthase, putative 0.023 0.0525 0.0524
Echinococcus granulosus NDR protein kinase 0.0165 0.0322 0.0311
Onchocerca volvulus Slit protein homolog 0.0281 0.0683 0.0651
Brugia malayi hypothetical protein 0.0099 0.0114 0.0114
Echinococcus multilocularis expressed conserved protein 0.0133 0.022 0.0213
Echinococcus multilocularis fibropellin Ia 0.0253 0.0596 0.0589
Schistosoma mansoni amine GPCR 0.0352 0.0906 0.0899
Brugia malayi Immunoglobulin domain containing protein 0.0135 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0117 0.0171 0.017
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0135 0.0225 0.0218
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0145
Schistosoma mansoni hypothetical protein 0.0135 0.0225 0.0218
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0368 0.0956 0.0949
Loa Loa (eye worm) variant SH3 domain-containing protein 0.009 0.0085 0.0085
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0113 0.0158 0.0158
Trypanosoma cruzi casein kinase, putative 0.0108 0.0142 0.0141
Echinococcus granulosus protein jagged 2 0.0253 0.0596 0.0586
Loa Loa (eye worm) casein kinase 0.0175 0.0351 0.0351
Echinococcus granulosus slit 2 protein 0.0281 0.0683 0.0673
Echinococcus granulosus titin 0.0162 0.0312 0.0301
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0262 0.0625 0.0625
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0253 0.0246
Entamoeba histolytica cyclin C, putative 0.0511 0.1402 0.1396
Brugia malayi Protein kinase domain containing protein 0.0185 0.0384 0.0384
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0221 0.0497 0.0489
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0084 0.0066 0.0042
Plasmodium falciparum calcium-dependent protein kinase 4 0.01 0.0118 0.008
Brugia malayi Calcium binding EGF domain containing protein 0.0253 0.0596 0.0596
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Echinococcus multilocularis casein kinase I delta 0.0108 0.0142 0.0134
Brugia malayi Protein kinase domain containing protein 0.009 0.0085 0.0085
Entamoeba histolytica disulphide oxidoreductase, putative 0.023 0.0525 0.0518
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.023 0.0525 0.0653
Echinococcus multilocularis c src tyrosine kinase 0.0136 0.023 0.0223
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0113 0.0157 0.0146
Trypanosoma cruzi casein kinase, putative 0.0108 0.0142 0.0141
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.019 0.0397 0.0387
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0467 0.1266 0.1265
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.023 0.0525 0.0515
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0162 0.031 0.03
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.019 0.0397 0.039
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Brugia malayi glutathione reductase 0.2505 0.7635 0.7635
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Echinococcus multilocularis neuroglian 0.0552 0.153 0.1523
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Schistosoma mansoni protein kinase 0.01 0.0116 0.0109
Echinococcus granulosus defective proboscis extension response 0.0439 0.1178 0.1168
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0218 0.0486 0.0486
Loa Loa (eye worm) TK/ABL protein kinase 0.0099 0.0114 0.0114
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.023 0.0525 0.0653
Schistosoma mansoni tyrosine kinase 0.0077 0.0045 0.0037
Echinococcus granulosus low density lipoprotein receptor ldl 0.0135 0.0225 0.0215
Schistosoma mansoni cell adhesion molecule 0.0262 0.0625 0.0618
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0143 0.0251 0.0241
Loa Loa (eye worm) AUR protein kinase 0.0144 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0175 0.0352 0.0352
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0173 0.0172
Loa Loa (eye worm) hypothetical protein 0.0188 0.0392 0.0391
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0232
Brugia malayi Protein kinase domain containing protein 0.0584 0.1631 0.1631
Echinococcus granulosus cGMP dependent protein kinase 1 0.0133 0.022 0.021
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0353 0.0908 0.1149
Trichomonas vaginalis STE family protein kinase 0.0086 0.0073 0.0072
Schistosoma mansoni hypothetical protein 0.0113 0.0157 0.0149
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0868 0.2518 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0358 0.0924 0.0915
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0221 0.0497 0.0486
Trichomonas vaginalis STE family protein kinase 0.0086 0.0073 0.0072
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.023 0.0525 0.0617
Echinococcus granulosus activin receptor type 0.0081 0.0057 0.0047
Echinococcus granulosus serine:threonine kinase SAD 1 0.0089 0.0083 0.0073
Schistosoma mansoni hypothetical protein 0.0099 0.0114 0.0106
Giardia lamblia Glutamate synthase 0.023 0.0525 0.0464
Entamoeba histolytica protein kinase, putative 0.0081 0.0059 0.0052
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.01 0.0118 0.0119
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0243 0.0243
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0134 0.0225 0.0221
Echinococcus granulosus dual specificity 0.0137 0.0234 0.0223
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2505 0.7635 1
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus granulosus casein kinase I alpha 0.0108 0.0142 0.0131
Echinococcus multilocularis tyrosine protein kinase otk 0.0247 0.0577 0.057
Plasmodium falciparum calcium-dependent protein kinase 5 0.01 0.0118 0.008
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.0173 0.0172
Treponema pallidum oxidoreductase 0.023 0.0525 0.182
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0081 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0139 0.0238 0.0238
Echinococcus granulosus protein kinase shaggy 0.0127 0.0202 0.0192
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.023 0.0525 0.1005
Trichomonas vaginalis AGC family protein kinase 0.0134 0.0225 0.0224
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0232 0.0529 0.0519
Echinococcus granulosus cyclin dependent kinase 0.0118 0.0173 0.0162
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0064 0.0057
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0071 0.0027 0.0017
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.023 0.0525 0.0646
Schistosoma mansoni titin 0.0162 0.0312 0.0304
Schistosoma mansoni cell adhesion molecule 0.0113 0.0157 0.0149
Schistosoma mansoni glycogen phosphorylase 0.141 0.4213 0.4209
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0083 0.0019
Brugia malayi Protein kinase domain containing protein 0.0209 0.0459 0.0459
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0114 0.0161 0.0151
Echinococcus multilocularis roundabout 2 0.0702 0.1998 0.1992
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0225 0.0225
Schistosoma mansoni ste20-related kinase 0.0201 0.0434 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0572 0.0565
Schistosoma mansoni protein kinase 0.0423 0.1128 0.1121
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0358 0.0924 0.0924
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0221 0.0497 0.0489
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0577 0.0577
Brugia malayi hypothetical protein 0.0135 0.0225 0.0225
Brugia malayi Immunoglobulin I-set domain containing protein 0.0923 0.269 0.269
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.023 0.0525 0.0617
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0069 0.0046
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0265 0.0632 0.0758
Loa Loa (eye worm) hypothetical protein 0.0089 0.0081 0.0081
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0108 0.0144 0.0144
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0066 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0576 0.0569
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Entamoeba histolytica PH domain containing protein kinase, putative 0.0121 0.0182 0.0175
Echinococcus granulosus netrin receptor unc 5 0.0163 0.0313 0.0303
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0121 0.0183 0.0196
Echinococcus granulosus tyrosine kinase 0.0099 0.0114 0.0104
Echinococcus multilocularis dual specificity 0.0137 0.0234 0.0226
Brugia malayi Protein kinase domain containing protein 0.019 0.04 0.04
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.0295 0.0343
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.0173 0.0172
Onchocerca volvulus 0.0113 0.0157 0.0123
Echinococcus granulosus fibropellin Ia 0.0253 0.0596 0.0586
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0262 0.0625 0.0618
Brugia malayi Protein kinase domain containing protein 0.0099 0.0114 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0221 0.0214
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0158 0.0151
Onchocerca volvulus Glycogen phosphorylase homolog 0.3262 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Brugia malayi Protein kinase domain containing protein 0.0113 0.0158 0.0158
Giardia lamblia Kinase, STE STE20 0.0085 0.0069 0.0005
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0247 0.0577 0.057
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0265 0.0632 0.0625
Loa Loa (eye worm) hypothetical protein 0.0108 0.0144 0.0143
Brugia malayi Protein kinase domain containing protein 0.0213 0.047 0.047
Brugia malayi Zinc finger, C2H2 type family protein 0.0138 0.0236 0.0236
Brugia malayi Serine/threonine-protein kinase SULU 0.0218 0.0486 0.0486
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0868 0.2518 0.3274
Schistosoma mansoni nephrin 0.0262 0.0625 0.0618
Plasmodium falciparum calcium-dependent protein kinase 1 0.01 0.0118 0.008
Echinococcus granulosus tyrosine protein kinase Lyn 0.0256 0.0604 0.0594
Loa Loa (eye worm) hypothetical protein 0.0128 0.0204 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0376 0.0368
Onchocerca volvulus 0.009 0.0085 0.0051
Brugia malayi Temporarily assigned gene name protein 59 0.0125 0.0196 0.0196
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0253 0.0252
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0089 0.0081 0.0074
Schistosoma mansoni cell polarity protein 0.0253 0.0596 0.0589
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0137 0.0234 0.0233
Onchocerca volvulus 0.0283 0.0691 0.0659
Brugia malayi putative serine/threonine kinase SADA gamma 0.0089 0.0083 0.0083
Mycobacterium tuberculosis Probable oxidoreductase 0.0868 0.2518 0.2803
Plasmodium falciparum serine/threonine protein kinase 0.0083 0.0064 0.0009
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0197 0.0421 0.0414
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3268
Echinococcus granulosus titin 0.0113 0.0157 0.0146
Brugia malayi serine/threonine protein kinase 6 0.0144 0.0253 0.0253
Entamoeba histolytica glutamate synthase beta subunit, putative 0.023 0.0525 0.0518
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0259 0.0614 0.0607
Schistosoma mansoni protein kinase 0.0108 0.0142 0.0134
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0157 0.0295 0.0313
Brugia malayi kettin 0.0113 0.0157 0.0157
Brugia malayi Animal haem peroxidase family protein 0.0113 0.0157 0.0157
Echinococcus granulosus tyrosine protein kinase 0.0279 0.0677 0.0667
Echinococcus multilocularis roundabout 2 0.0262 0.0625 0.0618
Echinococcus multilocularis serotonin transporter 0.0089 0.0081 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0247 0.0576 0.0576
Echinococcus multilocularis tyrosine protein kinase HCK 0.0132 0.0216 0.0209
Toxoplasma gondii CMGC kinase, CK2 family 0.01 0.0116 0.0116
Leishmania major casein kinase II, putative 0.01 0.0116 0.0077
Schistosoma mansoni c4b-binding protein beta chain 0.0467 0.1266 0.1259
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0135 0.0225 0.0218
Echinococcus granulosus voltage dependent calcium channel 0.019 0.0397 0.0387
Onchocerca volvulus 0.0089 0.0081 0.0048
Schistosoma mansoni titin 0.0113 0.0157 0.0149
Schistosoma mansoni nck2/grb4 0.009 0.0085 0.0078
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0868 0.2518 0.2513
Onchocerca volvulus 0.009 0.0085 0.0051
Loa Loa (eye worm) hypothetical protein 0.0089 0.0083 0.0083
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0127 0.0202 0.0195
Schistosoma mansoni tyrosine kinase 0.0537 0.1484 0.1478
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.0467 0.046
Loa Loa (eye worm) hypothetical protein 0.0139 0.0238 0.0238
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0127 0.0202 0.0192
Echinococcus multilocularis mitogen activated protein kinase 3 0.0084 0.0066 0.0059
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.023 0.0525 0.0524
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.023 0.0525 0.0617
Echinococcus multilocularis slit 2 protein 0.0281 0.0683 0.0676
Entamoeba histolytica protein kinase, putative 0.0285 0.0696 0.0689
Loa Loa (eye worm) TK protein kinase 0.0184 0.0381 0.0381
Trichomonas vaginalis glutathione reductase, putative 0.0868 0.2518 0.2517
Brugia malayi Fes/CIP4 homology domain containing protein 0.0111 0.015 0.015
Leishmania major protein kinase, putative 0.0151 0.0278 0.0291
Echinococcus granulosus thioredoxin glutathione reductase 0.2505 0.7635 0.7632
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.023 0.0525 0.0616
Echinococcus granulosus casein kinase ii subunit alpha 0.01 0.0116 0.0105
Echinococcus multilocularis Immunoglobulin 0.0439 0.1178 0.1171
Plasmodium falciparum NIMA related kinase 1 0.0134 0.0225 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0118 0.0117
Plasmodium falciparum thioredoxin reductase 0.2505 0.7635 1
Brugia malayi basement membrane proteoglycan 0.0135 0.0225 0.0225
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0395 0.1039 0.1029
Brugia malayi Protein kinase domain containing protein 0.0081 0.0059 0.0059
Entamoeba histolytica glycogen phosphorylase, putative 0.141 0.4213 0.4209
Echinococcus multilocularis NCK adaptor protein 0.0092 0.0091 0.0084
Schistosoma mansoni voltage-gated cation channel 0.019 0.0397 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0322 0.0314
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0138 0.0236 0.0234
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0228 0.0516 0.0516
Loa Loa (eye worm) hypothetical protein 0.019 0.0397 0.0397
Echinococcus multilocularis death associated protein kinase 1 0.0825 0.2384 0.2378
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0439 0.1178 0.1171
Onchocerca volvulus 0.0108 0.0142 0.0108
Leishmania major trypanothione reductase 0.2505 0.7635 1
Onchocerca volvulus 0.0113 0.0157 0.0123
Brugia malayi hypothetical protein 0.0455 0.1225 0.1225
Echinococcus multilocularis titin 0.0162 0.0312 0.0304
Trichomonas vaginalis mercuric reductase, putative 0.0868 0.2518 0.2517
Loa Loa (eye worm) hypothetical protein 0.0087 0.0075 0.0075
Schistosoma mansoni slit 0.0253 0.0597 0.059
Brugia malayi EGF-like domain containing protein 0.0253 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0262 0.0625 0.0625
Brugia malayi EGF-like domain containing protein 0.0253 0.0596 0.0596
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0085 0.0083
Echinococcus multilocularis aurora kinase A 0.0144 0.0253 0.0246
Echinococcus multilocularis transfer RNA-Phe 0.0128 0.0204 0.0197
Schistosoma mansoni protein kinase 0.0086 0.0073 0.0066
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0144 0.0253 0.0246
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0084 0.0066 0.0042
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0163 0.0314 0.0368
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0073 0.0066
Brugia malayi Protein kinase domain containing protein 0.0916 0.2668 0.2668
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0297 0.0732 0.0732
Brugia malayi casein kinase I 0.0108 0.0142 0.0142
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0173 0.0345 0.0345
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0125 0.0194 0.0181
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Brugia malayi Variant SH3 domain containing protein 0.009 0.0085 0.0085
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0253 0.0596 0.0564
Loa Loa (eye worm) hypothetical protein 0.0721 0.2057 0.2057
Echinococcus multilocularis tyrosine protein kinase Blk 0.0184 0.0381 0.0374
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.023 0.0525 0.0646
Entamoeba histolytica casein kinase, putative 0.01 0.0116 0.0109
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0066 0.0042
Leishmania major protein kinase, putative 0.0151 0.0278 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0221 0.0214
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.019 0.0397 0.039
Trypanosoma brucei aurora B kinase 0.0144 0.0253 0.0259
Echinococcus multilocularis netrin receptor unc 5 0.0163 0.0313 0.0306
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0083 0.0064 0.004
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0138 0.0236 0.0234
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.023 0.0525 0.0653
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0158 0.0148
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0108 0.0144 0.0136
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0073 0.0063
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0118 0.0111
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0868 0.2518 0.3248
Loa Loa (eye worm) hypothetical protein 0.0128 0.0204 0.0204
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0221 0.0497 0.0489
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.023 0.0525 0.0515
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0353 0.0908 0.1122
Leishmania major protein kinase A catalytic subunit isoform 1 0.0112 0.0155 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Entamoeba histolytica p21-activated kinase 0.0095 0.01 0.0093
Brugia malayi Protein kinase domain containing protein 0.0197 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0115 0.0165 0.0165
Loa Loa (eye worm) SRC-1 0.0221 0.0497 0.0496
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0084 0.0066 0.0012
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0393 0.1032 0.1022
Echinococcus multilocularis serine:threonine protein kinase 38 0.0165 0.0322 0.0314
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0221 0.0497 0.0489
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0202 0.0201
Schistosoma mansoni protein kinase 0.0081 0.0057 0.005
Echinococcus multilocularis casein kinase I alpha 0.0108 0.0142 0.0134
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0868 0.2518 0.3248
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0112 0.0155 0.0159
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0221 0.0497 0.0489
Onchocerca volvulus 0.0179 0.0365 0.0332
Echinococcus granulosus cyclin 0.0504 0.1379 0.137
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.014 0.0243 0.0243
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0113 0.0157 0.0149
Schistosoma mansoni hypothetical protein 0.0099 0.0114 0.0106
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0504 0.1379 0.137
Trichomonas vaginalis STE family protein kinase 0.0134 0.0225 0.0224
Echinococcus granulosus insulin growth factor binding 0.0113 0.0157 0.0146
Brugia malayi Furin-like cysteine rich region family protein 0.0594 0.1663 0.1663
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0165 0.0322 0.0311
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0078 0.0048 0.004
Leishmania major protein kinase A catalytic subunit isoform 2 0.0112 0.0155 0.0129
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0162 0.031 0.0303
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0074 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0135 0.0225 0.0218
Echinococcus granulosus protein kinase c iota type 0.0286 0.07 0.069
Loa Loa (eye worm) hypothetical protein 0.0247 0.0577 0.0577
Brugia malayi casein kinase 1, delta 0.0108 0.0142 0.0142
Echinococcus granulosus tyrosine protein kinase Src42A 0.014 0.0242 0.0232
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0113 0.0157 0.0149
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Echinococcus granulosus protein kinase c epsilon type 0.0207 0.0452 0.0442
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.0173 0.0152
Echinococcus granulosus nervana 2 0.012 0.018 0.0169
Echinococcus multilocularis tyrosine protein kinase Srms 0.0184 0.0381 0.0374
Echinococcus multilocularis fat cadherin tumor suppressor 0.0253 0.0596 0.0589
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.023 0.0525 0.1005
Schistosoma mansoni peroxidasin 0.0135 0.0226 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3268
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0078 0.0048 0.0037
Giardia lamblia High cysteine protein 0.0253 0.0596 0.0535
Onchocerca volvulus Serine\/threonine kinase homolog 0.0162 0.031 0.0277
Schistosoma mansoni tyrosine kinase 0.0136 0.023 0.0223
Loa Loa (eye worm) Notch2 0.0253 0.0596 0.0596
Entamoeba histolytica protein kinase, putative 0.0086 0.0073 0.0066
Trichomonas vaginalis disulfide oxidoreductase, putative 0.023 0.0525 0.0524
Onchocerca volvulus Peroxidasin homolog 0.0113 0.0158 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0204 0.0204
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0868 0.2518 0.3248
Echinococcus granulosus serine:threonine protein kinase 3 0.0252 0.0591 0.0581
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0221 0.0497 0.0489
Loa Loa (eye worm) hypothetical protein 0.0202 0.0436 0.0436
Schistosoma mansoni titin 0.0113 0.0157 0.0149
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0093 0.0096 0.0086
Schistosoma mansoni tyrosine kinase 0.0346 0.0887 0.088
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus multilocularis cyclin dependent kinase 19 0.0682 0.1936 0.193
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.023 0.0525 0.0646
Echinococcus granulosus Protein kinase C brain isozyme 0.0246 0.0572 0.0562
Schistosoma mansoni hypothetical protein 0.0135 0.0225 0.0218
Brugia malayi Protein kinase domain containing protein 0.0151 0.0278 0.0278
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0093 0.0096 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0486 0.0479
Echinococcus granulosus Vam6:Vps39 protein 0.0108 0.0144 0.0133
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0344 0.0881 0.085
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0253 0.0252
Onchocerca volvulus Netrin receptor homolog 0.0141 0.0244 0.0211
Brugia malayi pregnancy-associated plasma protein-A 0.0467 0.1266 0.1266
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0108 0.0142 0.0142
Toxoplasma gondii rhoptry neck protein RON1 0.0467 0.1266 0.1627
Schistosoma mansoni hypothetical protein 0.023 0.0525 0.0518
Echinococcus multilocularis Glutaredoxin protein 5 0.012 0.018 0.0172
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0989 0.2895 0.2887
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0157 0.0295 0.0313
Loa Loa (eye worm) disorganized muscle protein 1 0.0113 0.0157 0.0156
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.0467 0.0457
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0135 0.0225 0.0218
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0112 0.0155 0.0129
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0144 0.0253 0.0246
Echinococcus granulosus nervana 2 0.012 0.018 0.0169
Schistosoma mansoni laminin gamma-3 chain 0.0253 0.0596 0.0589
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.0253 0.0246
Schistosoma mansoni notch 0.0253 0.0596 0.0589
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Brugia malayi Protein kinase domain containing protein 0.0099 0.0114 0.0114
Schistosoma mansoni notch 0.0253 0.0596 0.0589
Plasmodium falciparum glutathione reductase 0.0868 0.2518 0.3248
Echinococcus granulosus sulfide:quinone oxidoreductase 0.023 0.0525 0.0515
Trypanosoma cruzi NADH dehydrogenase, putative 0.023 0.0525 0.0646
Plasmodium vivax serine/threonine kinase-1, putative 0.0151 0.0278 0.0291
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0253 0.0252
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0121 0.0183 0.0166
Brugia malayi Sushi domain 0.0467 0.1266 0.1266
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0923 0.269 0.269
Onchocerca volvulus 0.0108 0.0144 0.011
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0207 0.0452 0.0452
Echinococcus granulosus neuroglian 0.0262 0.0625 0.0615
Trypanosoma cruzi hypothetical protein, conserved 0.023 0.0525 0.0646
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0151 0.0278 0.0291
Echinococcus multilocularis epidermal growth factor receptor 0.0594 0.1663 0.1656
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0143 0.0251 0.0244
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0081 0.0059 0.0052
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0262 0.0625 0.0618
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Schistosoma mansoni tyrosine kinase 0.0346 0.0887 0.088
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0202 0.0201
Schistosoma mansoni cell adhesion molecule 0.0128 0.0204 0.0197
Trypanosoma cruzi casein kinase II, putative 0.01 0.0116 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0173 0.0165
Brugia malayi Hr1 repeat family protein 0.0291 0.0715 0.0715
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3268
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0148
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0093 0.0096 0.0096
Echinococcus granulosus twitchin 0.0586 0.1637 0.1628
Plasmodium vivax glutathione reductase, putative 0.2505 0.7635 1
Brugia malayi serine/threonine kinase 12 0.0144 0.0253 0.0253
Echinococcus granulosus tyrosine protein kinase otk 0.0247 0.0577 0.0567
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0135 0.0225 0.0218
Schistosoma mansoni growth factor receptor-bound protein 0.009 0.0085 0.0078
Echinococcus multilocularis rac serine:threonine kinase 0.0163 0.0314 0.0307
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0232
Echinococcus granulosus tyrosine protein kinase ABL1 0.0099 0.0114 0.0104
Brugia malayi cell division control protein 2 homolog 0.0118 0.0173 0.0173
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0081 0.0059 0.0059
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.023 0.0525 0.0525
Echinococcus granulosus Immunoglobulin 0.0135 0.0225 0.0215
Loa Loa (eye worm) cyclin C 0.1015 0.2976 0.2976
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Schistosoma mansoni tyrosine kinase 0.0393 0.1032 0.1025
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0087 0.0077 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0384 0.0382
Brugia malayi Cyclin C 0.1015 0.2976 0.2976
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0344 0.0881 0.0881
Loa Loa (eye worm) hypothetical protein 0.0439 0.1178 0.1178
Toxoplasma gondii rhoptry neck protein RON9 0.0467 0.1266 0.1627
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.01 0.0118 0.008
Echinococcus granulosus titin 0.0162 0.0312 0.0301
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0081 0.0058 0.0001
Toxoplasma gondii selenide, water dikinase 0.023 0.0525 0.0653
Plasmodium falciparum dihydroorotate dehydrogenase 0.0353 0.0908 0.1123
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.019 0.0397 0.0387
Plasmodium vivax apical sushi protein, putative 0.0467 0.1266 0.1594
Schistosoma mansoni cell adhesion molecule 0.0247 0.0577 0.057
Trichomonas vaginalis glycogen phosphorylase, putative 0.3262 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0163 0.0314 0.0307
Leishmania major hypothetical protein, conserved 0.023 0.0525 0.0617
Brugia malayi SH2 domain containing protein 0.0099 0.0114 0.0114
Echinococcus granulosus cyclin dependent kinase 19 0.0682 0.1936 0.1927
Echinococcus granulosus contactin 0.0262 0.0625 0.0615
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0197 0.0421 0.0411
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.0142 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0632 0.0625
Brugia malayi Egg laying defective protein 4 0.0133 0.022 0.022
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.141 0.4213 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0868 0.2518 0.2803
Echinococcus granulosus protein jagged 1 0.0253 0.0596 0.0586
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.01 0.0118 0.0118
Brugia malayi protein kinase C II. 0.0207 0.0452 0.0452
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0837 0.2421 0.2416
Schistosoma mansoni cell adhesion molecule 0.0128 0.0204 0.0197
Schistosoma mansoni vam6/vps39 related 0.0108 0.0144 0.0136
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0157 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.0264 0.0257
Echinococcus multilocularis serine:threonine protein kinase N2 0.0126 0.0198 0.0191
Giardia lamblia Kinase, CMGC GSK 0.0127 0.0202 0.0139
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0868 0.2518 0.2518
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0226 0.0226
Schistosoma mansoni basigin related 0.0135 0.0225 0.0218
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0118 0.0111
Loa Loa (eye worm) serotonin transporter b 0.0089 0.0081 0.0081
Echinococcus granulosus voltage dependent calcium channel 0.0081 0.0059 0.0048
Brugia malayi Protein kinase domain containing protein 0.0099 0.0114 0.0114
Echinococcus granulosus mitogen activated protein kinase 11 0.0157 0.0295 0.0284
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.0173 0.0171
Entamoeba histolytica protein kinase, putative 0.0144 0.0253 0.0246
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0165 0.0322 0.0311
Loa Loa (eye worm) hypothetical protein 0.0079 0.0052 0.0052
Echinococcus granulosus protein kinase C gamma type 0.0205 0.0446 0.0435
Onchocerca volvulus 0.0135 0.0226 0.0192
Loa Loa (eye worm) AGC/PKA protein kinase 0.0112 0.0155 0.0155
Toxoplasma gondii AGC kinase 0.0112 0.0155 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0194 0.0411 0.0409
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0127 0.0202 0.0221
Schistosoma mansoni hypothetical protein 0.0113 0.0157 0.0149
Loa Loa (eye worm) hypothetical protein 0.0135 0.0226 0.0225
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0584 0.1631 0.1631
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0157 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Brugia malayi Protein kinase domain containing protein 0.0437 0.117 0.117
Loa Loa (eye worm) TK/ROR protein kinase 0.0159 0.0302 0.0301
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.023 0.0525 0.0525
Brugia malayi GCC2 and GCC3 family protein 0.0721 0.2057 0.2057
Echinococcus granulosus neurogenic locus notch protein 0.0253 0.0596 0.0586
Loa Loa (eye worm) hypothetical protein 0.0225 0.0508 0.0508
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0322 0.032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0577 0.0577
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0196 0.0194
Schistosoma mansoni serine/threonine-protein kinase 0.0163 0.0314 0.0307
Loa Loa (eye worm) hypothetical protein 0.0281 0.0683 0.0683
Onchocerca volvulus 0.0467 0.1266 0.1236
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0525 0.0518
Brugia malayi Protein kinase domain containing protein 0.0189 0.0397 0.0397
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0118 0.0111
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0452 0.1217 0.1211
Brugia malayi Thioredoxin reductase 0.2505 0.7635 0.7635
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0197 0.0421 0.0421
Schistosoma mansoni vav2 0.0102 0.0123 0.0116
Echinococcus granulosus epidermal growth factor receptor 0.0393 0.1032 0.1022
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0278 0.0271
Loa Loa (eye worm) AGC/PKG protein kinase 0.0133 0.022 0.022
Loa Loa (eye worm) TK protein kinase 0.0279 0.0677 0.0676
Schistosoma mansoni serine/threonine kinase 0.0165 0.0322 0.0314
Echinococcus granulosus mitogen activated protein kinase 14 0.0157 0.0295 0.0284
Loa Loa (eye worm) hypothetical protein 0.009 0.0085 0.0085
Plasmodium vivax casein kinase 1, putative 0.0108 0.0142 0.0111
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0121 0.0183 0.0196
Echinococcus multilocularis Immunoglobulin 0.0439 0.1178 0.1171
Giardia lamblia Kinase, CMGC MAPK 0.0084 0.0066 0.0002
Echinococcus granulosus delta-like protein 1 0.0253 0.0596 0.0586
Loa Loa (eye worm) AGC/AKT protein kinase 0.0294 0.0724 0.0723
Plasmodium vivax serine/threonine protein kinase, putative 0.0083 0.0064 0.0008
Trichomonas vaginalis disulfide oxidoreductase, putative 0.023 0.0525 0.0524
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0173 0.0109
Schistosoma mansoni nephrin related 0.0135 0.0225 0.0218
Echinococcus granulosus insulin receptor 0.0437 0.117 0.116
Brugia malayi Fibronectin type III domain containing protein 0.0455 0.1225 0.1225
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0421 0.0414
Schistosoma mansoni cell adhesion molecule 0.0135 0.0225 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0148
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Loa Loa (eye worm) gastrulation defective protein 1 0.0647 0.1828 0.1828
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0157 0.0156
Schistosoma mansoni protein kinase C mu 0.0214 0.0472 0.0465
Toxoplasma gondii transporter, cation channel family protein 0.0081 0.0059 0.004
Schistosoma mansoni titin 0.0113 0.0157 0.0149
Leishmania major protein kinase, putative 0.0085 0.0069 0.0016
Plasmodium falciparum apical sushi protein 0.0467 0.1266 0.1595
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0232 0.0529 0.0522
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0452 0.1217 0.1208
Loa Loa (eye worm) hypothetical protein 0.0083 0.0065 0.0065
Echinococcus multilocularis casein kinase I gamma 0.0209 0.0459 0.0452
Trypanosoma cruzi NADH dehydrogenase, putative 0.023 0.0525 0.0646
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0127 0.0202 0.0192
Toxoplasma gondii thioredoxin reductase 0.2505 0.7635 1
Schistosoma mansoni septate junction protein 0.0247 0.0577 0.057
Schistosoma mansoni basigin related 0.0135 0.0225 0.0218
Leishmania major hypothetical protein, conserved 0.023 0.0525 0.0617
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.0173 0.0165
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0353 0.0908 0.1123
Echinococcus multilocularis Immunoglobulin subtype 0.0135 0.0225 0.0218
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0214 0.0472 0.0472
Echinococcus multilocularis insulin receptor 0.0437 0.117 0.1163
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Entamoeba histolytica serine/threonine protein kinase, putative 0.0265 0.0632 0.0625
Echinococcus granulosus glycogen phosphorylase 0.3262 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0151 0.0278 0.0277
Plasmodium vivax calcium-dependent protein kinase, putative 0.01 0.0118 0.0079
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.023 0.0525 0.0518
Echinococcus multilocularis hypothetical protein 0.0099 0.0114 0.0106
Schistosoma mansoni septate junction protein 0.0135 0.0225 0.0218
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0368 0.0956 0.0946
Onchocerca volvulus 0.0099 0.0114 0.008
Echinococcus multilocularis myosin iiia 0.0085 0.0069 0.0062
Trichomonas vaginalis disulfide oxidoreductase, putative 0.023 0.0525 0.0524
Mycobacterium ulcerans glutamate synthase subunit beta 0.023 0.0525 0.1005
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0128 0.0204 0.0194
Echinococcus granulosus c4b binding protein beta chain 0.0467 0.1266 0.1256
Schistosoma mansoni tyrosine kinase 0.0221 0.0497 0.0489
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Echinococcus multilocularis 0.0117 0.0171 0.0163
Schistosoma mansoni titin 0.0113 0.0157 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0232
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0151 0.0278 0.0321
Echinococcus granulosus tm gpcr rhodopsin 0.0837 0.2421 0.2413
Brugia malayi Variant SH3 domain containing protein 0.0093 0.0096 0.0096
Schistosoma mansoni roundabout 0.0247 0.0577 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.016 0.0153
Giardia lamblia Kinase, AGC PKA 0.0154 0.0287 0.0224
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0089 0.0083 0.0065
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0439 0.1178 0.1171
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Echinococcus multilocularis 0.0113 0.0157 0.0149
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0084 0.0066 0.005
Loa Loa (eye worm) voltage-dependent calcium channel 0.0081 0.0059 0.0058
Loa Loa (eye worm) cyclin domain-containing protein 0.0504 0.1379 0.1379
Echinococcus multilocularis serine:threonine protein kinase N2 0.0165 0.0322 0.0314
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0138 0.0236 0.0234
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0138 0.0236 0.0265
Schistosoma mansoni tyrosine kinase 0.0437 0.117 0.1163
Onchocerca volvulus Neurogenic locus notch homolog 0.0253 0.0596 0.0564
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0151 0.0276 0.0275
Echinococcus multilocularis neuroglian 0.0262 0.0625 0.0618
Echinococcus granulosus dual specificity 0.0121 0.0183 0.0173
Echinococcus multilocularis calcium dependent protein kinase 0.0066 0.0011 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Echinococcus multilocularis glycogen phosphorylase 0.3262 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0577 0.0577
Brugia malayi Immunoglobulin I-set domain containing protein 0.0262 0.0625 0.0625
Brugia malayi Protein kinase domain containing protein 0.0118 0.0173 0.0173
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.0173 0.0182
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.0173 0.0152
Trypanosoma brucei trypanothione reductase 0.2505 0.7635 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0285 0.0696 0.0696
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0084 0.0066 0.0012
Loa Loa (eye worm) hypothetical protein 0.0455 0.1225 0.1225
Schistosoma mansoni titin 0.0128 0.0204 0.0197
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0395 0.1039 0.1032
Schistosoma mansoni serine/threonine protein kinase 0.0465 0.1258 0.1252
Brugia malayi Protein kinase domain containing protein 0.0165 0.0322 0.0322
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0385 0.1007 0.1001
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0084 0.0066 0.0012
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.0173 0.0152
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0138 0.0236 0.0234
Giardia lamblia Kinase, CDC7 0.009 0.0085 0.002
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.0467 0.046
Echinococcus multilocularis nervana 2 0.012 0.018 0.0172
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0113 0.0158 0.015
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0247 0.0577 0.0545
Echinococcus granulosus serine:threonine protein kinase N2 0.0126 0.0198 0.0187
Schistosoma mansoni glutamate synthase 0.023 0.0525 0.0518
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0574 0.1598 0.159
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0071 0.0027 0.0017
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0158 0.0151
Brugia malayi Protein kinase domain containing protein 0.0162 0.031 0.031
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0183 0.0376 0.0376
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0199 0.0427 0.0427
Schistosoma mansoni hypothetical protein 0.0135 0.0225 0.0218
Schistosoma mansoni growth factor receptor-bound protein 0.0092 0.0091 0.0084
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0353 0.0908 0.0539
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus granulosus calcium activated potassium channel 0.0143 0.0252 0.0241
Trichomonas vaginalis AGC family protein kinase 0.0144 0.0253 0.0252
Echinococcus granulosus c src tyrosine kinase 0.0136 0.023 0.0219
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Leishmania major dihydroorotate dehydrogenase 0.0353 0.0908 0.1123
Echinococcus granulosus N chimaerin 0.0093 0.0096 0.0086
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0157 0.0295 0.0295
Giardia lamblia Kinase, CMGC DYRK 0.0137 0.0234 0.017
Brugia malayi Immunoglobulin I-set domain containing protein 0.015 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0108 0.0144 0.0143
Echinococcus multilocularis activin receptor type 0.0081 0.0057 0.005
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Onchocerca volvulus 0.0113 0.0157 0.0123
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0143 0.0251 0.0244
Brugia malayi phosphoinositide-dependent protein kinase I 0.0081 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus multilocularis casein kinase I alpha 0.0108 0.0142 0.0134
Onchocerca volvulus 0.0467 0.1266 0.1236
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0108 0.0144 0.0136
Echinococcus granulosus neurogenic locus notch protein 4 0.0253 0.0596 0.0586
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.141 0.4213 0.5187
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0162 0.031 0.031
Echinococcus granulosus cGMP dependent protein kinase 0.0133 0.022 0.021
Schistosoma mansoni cell adhesion molecule 0.0262 0.0625 0.0618
Echinococcus multilocularis voltage dependent calcium channel 0.019 0.0397 0.039
Schistosoma mansoni hypothetical protein 0.0113 0.0157 0.0149
Brugia malayi intracellular kinase 0.0127 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Onchocerca volvulus 0.0253 0.0596 0.0564
Echinococcus granulosus casein kinase I alpha 0.0108 0.0142 0.0131
Loa Loa (eye worm) glutathione reductase 0.2505 0.7635 0.7635
Echinococcus multilocularis CDC7 cell division cycle 7 0.009 0.0085 0.0077
Brugia malayi Prion-like- 0.0247 0.0577 0.0577
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0161 0.016
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0246 0.0572 0.0565
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Echinococcus granulosus titin 0.0113 0.0157 0.0146
Brugia malayi EGF-like domain containing protein 0.0253 0.0596 0.0596
Echinococcus granulosus dual specificity protein kinase clk2 0.0151 0.0278 0.0268
Loa Loa (eye worm) hypothetical protein 0.0071 0.0028 0.0028
Echinococcus granulosus cGMP dependent protein kinase 1 0.0133 0.022 0.021
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0232
Trypanosoma brucei SNF1-related protein kinases, putative 0.0089 0.0083 0.0034
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.0173 0.0165
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0239 0.0551 0.0544
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0353 0.0908 0.1157
Schistosoma mansoni tyrosine kinase 0.0294 0.0722 0.0715
Giardia lamblia NADH oxidase lateral transfer candidate 0.0868 0.2518 0.247
Loa Loa (eye worm) notch protein 0.0253 0.0596 0.0596
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0285 0.0696 0.0696
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Echinococcus granulosus casein kinase i 0.0108 0.0142 0.0131
Echinococcus granulosus roundabout 2 0.0702 0.1998 0.1989
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0159 0.0302 0.0294
Onchocerca volvulus 0.0467 0.1266 0.1236
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0199 0.0427 0.0426
Echinococcus multilocularis Immunoglobulin 0.0135 0.0225 0.0218
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0183 0.0376 0.0368
Plasmodium falciparum protein kinase 5 0.0118 0.0173 0.0152
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0213 0.047 0.047
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0151 0.0278 0.0278
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0358 0.0924 0.0917
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0155 0.0148
Brugia malayi protein unc-22 0.0162 0.0312 0.0312
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0112 0.0155 0.0129
Echinococcus granulosus protein jagged 1 0.0253 0.0596 0.0586
Onchocerca volvulus 0.0253 0.0596 0.0564
Entamoeba histolytica glycogen phosphorylase, putative 0.3262 1 1
Entamoeba histolytica protein kinase domain containing protein 0.01 0.0116 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Entamoeba histolytica glutamate synthase beta subunit, putative 0.023 0.0525 0.0518
Echinococcus granulosus tyrosine protein kinase Src42A 0.0221 0.0497 0.0486
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0584 0.1631 0.1631
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.023 0.0525 0.0617
Loa Loa (eye worm) LAD-2 short isoform 0.0135 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0112 0.0155 0.0129
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus multilocularis neurogenic locus notch protein 4 0.0253 0.0596 0.0589
Loa Loa (eye worm) hypothetical protein 0.0108 0.0144 0.0143
Echinococcus multilocularis tyrosine protein kinase shark 0.0306 0.0761 0.0755
Loa Loa (eye worm) hypothetical protein 0.0247 0.0577 0.0577
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0225 0.0225
Plasmodium vivax protein kinase Crk2 0.0118 0.0173 0.0151
Brugia malayi Protein kinase c protein 2 0.0115 0.0163 0.0163
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0151 0.0277 0.0276
Schistosoma mansoni neuroglian 0.0262 0.0625 0.0618
Onchocerca volvulus 0.0253 0.0596 0.0564
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0089 0.0083 0.0083
Echinococcus multilocularis tyrosine protein kinase Abl 0.0136 0.023 0.0223
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0081 0.0058 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0278 0.0271
Echinococcus multilocularis nervana 2 0.012 0.018 0.0172
Entamoeba histolytica protein kinase, putative 0.01 0.0118 0.0111
Brugia malayi Kinase associated domain 1 family protein 0.0099 0.0114 0.0114
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.0173 0.0182
Brugia malayi Immunoglobulin domain containing protein 0.0135 0.0225 0.0225
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3268
Loa Loa (eye worm) hypothetical protein 0.0135 0.0225 0.0225
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0183 0.0376 0.0365
Mycobacterium ulcerans NADH dehydrogenase 0.023 0.0525 0.1005
Echinococcus granulosus Immunoglobulin 0.0135 0.0225 0.0215
Echinococcus multilocularis thioredoxin glutathione reductase 0.2505 0.7635 0.7633
Brugia malayi Cam kinase protein 1 0.01 0.0118 0.0118
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0218 0.0486 0.0476
Onchocerca volvulus 0.0113 0.0157 0.0123
Brugia malayi Protein kinase domain containing protein 0.0279 0.0677 0.0677
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0439 0.1178 0.1171
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0083 0.0064 0.0009
Schistosoma mansoni septate junction protein 0.0247 0.0577 0.057
Trypanosoma cruzi trypanothione reductase, putative 0.2505 0.7635 1
Brugia malayi Protein kinase domain containing protein 0.0294 0.0724 0.0724
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.023 0.0525 0.0653
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.023 0.0525 0.1005
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0234 0.0226
Echinococcus multilocularis C type lectin domian containing protein 0.0467 0.1266 0.1259
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Echinococcus granulosus mitogen activated protein kinase 3 0.0084 0.0066 0.0056
Echinococcus granulosus epidermal growth factor receptor 0.0594 0.1663 0.1654
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0142 0.0134
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0112 0.0155 0.0159
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0135 0.0225 0.0225
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0368 0.0956 0.0949
Brugia malayi MAP kinase sur-1 0.0084 0.0066 0.0066
Giardia lamblia Kinase, CMGC CLK 0.0151 0.0278 0.0215
Echinococcus granulosus neural cadherin 0.0253 0.0596 0.0586
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Brugia malayi Protein kinase domain containing protein 0.0099 0.0114 0.0114
Plasmodium vivax ferrodoxin reductase, putative 0.023 0.0525 0.0616
Trypanosoma brucei protein kinase, putative 0.0084 0.0066 0.0012
Trypanosoma cruzi casein kinase, putative 0.0108 0.0142 0.0141
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0638 0.1798 0.1798
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0161 0.016
Onchocerca volvulus 0.0467 0.1266 0.1236
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0179 0.0365 0.0364
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0265 0.0632 0.0622
Entamoeba histolytica protein kinase, putative 0.0165 0.0322 0.0314
Giardia lamblia Kinase, CMGC CDK 0.0118 0.0173 0.0109
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0393 0.1034 0.1027
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0199 0.0427 0.042
Loa Loa (eye worm) TK/FAK protein kinase 0.0543 0.1502 0.1502
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.023 0.0525 0.0518
Plasmodium falciparum glycogen synthase kinase 3 0.0127 0.0202 0.0192
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0085 0.0069 0.0062
Loa Loa (eye worm) hypothetical protein 0.052 0.143 0.1429
Brugia malayi protein-tyrosine kinase 0.0184 0.0381 0.0381
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0868 0.2518 0.3248
Giardia lamblia Thioredoxin reductase 0.023 0.0525 0.0464
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Loa Loa (eye worm) thyroid receptor interactor 0.0111 0.015 0.015
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0113 0.0158 0.0147
Echinococcus multilocularis tyrosine protein kinase 0.0279 0.0677 0.067
Echinococcus multilocularis 0.0168 0.0331 0.0324
Entamoeba histolytica protein kinase, putative 0.0121 0.0183 0.0176
Schistosoma mansoni netrin receptor unc5 0.0163 0.0313 0.0306
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0099 0.0114 0.0107
Schistosoma mansoni tyrosine kinase 0.0253 0.0597 0.059
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0232
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0504 0.1379 0.1373
Loa Loa (eye worm) hypothetical protein 0.0081 0.0059 0.0058
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0202 0.0195
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0353 0.0908 0.1149
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Chlamydia trachomatis glycogen phosphorylase 0.3262 1 1
Giardia lamblia Aurora kinase 0.0144 0.0253 0.019
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.01 0.0118 0.0119
Echinococcus multilocularis hemicentin 1 0.0247 0.0577 0.057
Onchocerca volvulus 0.0099 0.0114 0.008
Schistosoma mansoni nephrin 0.0567 0.1577 0.1571
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0085 0.0069 0.0046
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0239 0.0551 0.0541
Schistosoma mansoni g1/s-specific cyclin C 0.1015 0.2976 0.2971
Leishmania major protein kinase A catalytic subunit 0.0112 0.0155 0.0129
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3268
Loa Loa (eye worm) projectin 0.0128 0.0204 0.0204
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0868 0.2518 0.5866
Echinococcus multilocularis notch 0.0253 0.0596 0.0589
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0385 0.1007 0.1007
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0423 0.1128 0.1118
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0312 0.0304
Onchocerca volvulus 0.0127 0.0202 0.0169
Loa Loa (eye worm) AGC/PKN protein kinase 0.0291 0.0715 0.0714
Echinococcus granulosus tyrosine protein kinase Src64B 0.0221 0.0497 0.0486
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0112 0.0155 0.0129
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0423 0.1128 0.1121
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.01 0.0118 0.0119
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0133 0.022 0.0213
Brugia malayi Variant SH3 domain containing protein 0.009 0.0085 0.0085
Echinococcus granulosus protein kinase 0.0151 0.0277 0.0266
Brugia malayi Calcium binding EGF domain containing protein 0.0253 0.0596 0.0596
Schistosoma mansoni tyrosine kinase 0.0437 0.117 0.1163
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0081 0.0059 0.0049
Schistosoma mansoni slit 0.0113 0.0158 0.015
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0262 0.0625 0.0618
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Schistosoma mansoni atypical protein kinase C 0.0292 0.0718 0.0711
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0112 0.0155 0.0167
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0145
Schistosoma mansoni protein kinase 0.0151 0.0277 0.0269
Giardia lamblia Kinase, NEK 0.0134 0.0225 0.0162
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0128 0.0204 0.0204
Echinococcus multilocularis epidermal growth factor receptor 0.0393 0.1032 0.1025
Entamoeba histolytica casein kinase 1, putative 0.0108 0.0142 0.0134
Onchocerca volvulus 0.0303 0.0751 0.072
Echinococcus multilocularis Immunoglobulin 0.0135 0.0225 0.0218
Plasmodium falciparum serine/threonine protein kinase, putative 0.0144 0.0253 0.0259
Entamoeba histolytica protein kinase domain containing protein 0.0121 0.0183 0.0176
Echinococcus multilocularis casein kinase ii subunit alpha 0.01 0.0116 0.0109
Onchocerca volvulus 0.0139 0.0238 0.0204
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.0173 0.0162
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0084 0.0066 0.0066
Trichomonas vaginalis AGC family protein kinase 0.0294 0.0724 0.0722
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.0173 0.0152
Schistosoma mansoni septate junction protein 0.0135 0.0225 0.0218
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0337 0.086 0.0859
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0212 0.0467 0.0457
Plasmodium falciparum casein kinase 1 0.0108 0.0142 0.0112
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.01 0.0116 0.0114
Loa Loa (eye worm) hypothetical protein 0.0439 0.1178 0.1178
Brugia malayi P38 map kinase family protein 2 0.0157 0.0295 0.0295
Brugia malayi Immunoglobulin domain containing protein 0.0135 0.0225 0.0225
Entamoeba histolytica casein kinase, putative 0.0108 0.0142 0.0134
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0144 0.0253 0.0246
Loa Loa (eye worm) hypothetical protein 0.0113 0.0157 0.0156
Onchocerca volvulus 0.0128 0.0204 0.0171
Entamoeba histolytica protein kinase, putative 0.0074 0.0035 0.0027
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0071 0.0027 0.002
Echinococcus multilocularis serine threonine protein kinase 0.0205 0.0446 0.0438
Loa Loa (eye worm) hypothetical protein 0.0135 0.0225 0.0225
Echinococcus multilocularis protein tyrosine kinase 0.0537 0.1484 0.1478
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0353 0.0908 0.1939
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0135 0.0225 0.0218
Schistosoma mansoni rap gtpase-activating protein 0.0108 0.0144 0.0136
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.0173 0.0162
Onchocerca volvulus 0.0113 0.0157 0.0123
Brugia malayi Prion-like- 0.0113 0.0157 0.0157
Echinococcus multilocularis peroxidasin 0.0247 0.0578 0.0571
Brugia malayi C1-like domain containing protein 0.0214 0.0472 0.0472
Echinococcus multilocularis serine:threonine protein kinase 3 0.0252 0.0591 0.0584
Entamoeba histolytica protein kinase, putative 0.0144 0.0253 0.0246
Entamoeba histolytica protein kinase, putative 0.0087 0.0077 0.0069
Echinococcus multilocularis neurogenic locus protein delta 0.0253 0.0596 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0158 0.0157
Trichomonas vaginalis disulfide oxidoreductase, putative 0.023 0.0525 0.0524
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Brugia malayi Leucine Rich Repeat family protein 0.0113 0.0158 0.0158
Loa Loa (eye worm) norepinephrine transporter 0.0089 0.0081 0.0081
Schistosoma mansoni tyrosine kinase 0.0393 0.1032 0.1025
Echinococcus multilocularis mitogen activated protein kinase 11 0.0157 0.0295 0.0288
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0083 0.0064 0.0064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0135 0.0225 0.0225
Brugia malayi Muscle positioning protein 4 0.0253 0.0596 0.0596
Schistosoma mansoni glycogen phosphorylase 0.3262 1 1
Loa Loa (eye worm) hypothetical protein 0.0247 0.0577 0.0577
Brugia malayi EGF-like domain containing protein 0.0253 0.0596 0.0596
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.01 0.0116 0.0116
Echinococcus granulosus serine:threonine protein kinase N2 0.0291 0.0715 0.0705
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0151 0.0278 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0459 0.0452
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0221 0.0497 0.0489
Brugia malayi Prion-like- 0.0113 0.0157 0.0157
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0134 0.0225 0.0259
Toxoplasma gondii NADPH-glutathione reductase 0.0868 0.2518 0.3274
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Entamoeba histolytica protein kinase, putative 0.0121 0.0183 0.0176
Echinococcus multilocularis cyclin 0.0504 0.1379 0.1373
Plasmodium falciparum calcium-dependent protein kinase 2 0.01 0.0118 0.008
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.023 0.0525 0.0518
Echinococcus multilocularis twitchin 0.0147 0.0264 0.0257
Loa Loa (eye worm) AGC/NDR protein kinase 0.0165 0.0322 0.0321
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0157 0.0156
Plasmodium falciparum protein serine/threonine kinase-1 0.0151 0.0278 0.0291
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Leishmania major protein kinase, putative 0.0144 0.0253 0.0259
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.022 0.0213
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0086 0.0073 0.0066
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0868 0.2518 0.3247
Leishmania major hypothetical protein, conserved 0.023 0.0525 0.0617
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0393 0.1034 0.1024
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0323 0.0815 0.0814
Entamoeba histolytica protein kinase, putative 0.0132 0.0216 0.0209
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0083 0.0064 0.0048
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Onchocerca volvulus 0.0162 0.0312 0.0279
Loa Loa (eye worm) TK protein kinase 0.0132 0.0216 0.0216
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0577 0.0577
Onchocerca volvulus 0.0467 0.1266 0.1236
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.023 0.0525 0.0518
Brugia malayi hypothetical protein 0.0108 0.0144 0.0144
Schistosoma mansoni disulfide oxidoreductase 0.023 0.0525 0.0518
Trypanosoma cruzi polo-like protein kinase, putative 0.0265 0.0632 0.0786
Loa Loa (eye worm) hypothetical protein 0.0139 0.024 0.024
Brugia malayi EGF-like domain containing protein 0.0281 0.0683 0.0683
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0353 0.0908 0.0908
Echinococcus granulosus Glutaredoxin protein 5 0.012 0.018 0.0169
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0086 0.0073 0.0063
Brugia malayi map kinase activated protein kinase protein 2 0.0385 0.1007 0.1007
Mycobacterium ulcerans hypothetical protein 0.023 0.0525 0.1005
Schistosoma mansoni serine/threonine kinase 0.0213 0.047 0.0463
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0085 0.0069 0.0062
Onchocerca volvulus Putative cubilin 0.0253 0.0596 0.0564
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0202 0.0195
Toxoplasma gondii AGC kinase 0.0112 0.0155 0.0167
Echinococcus granulosus casein kinase I alpha 0.0108 0.0142 0.0131
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0154 0.0287 0.028
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.0142 0.0142
Trichomonas vaginalis STE family protein kinase 0.0086 0.0073 0.0072
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0157 0.0295 0.0343
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0252 0.0591 0.0591
Entamoeba histolytica protein kinase, putative 0.0083 0.0064 0.0057
Brugia malayi Protein kinase domain containing protein 0.0276 0.0667 0.0667
Echinococcus granulosus roundabout 2 0.0262 0.0625 0.0615
Treponema pallidum thioredoxin reductase (trxB) 0.023 0.0525 0.182
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0183 0.0176
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0113 0.0157 0.0149
Schistosoma mansoni sulfide quinone reductase 0.023 0.0525 0.0518
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0185 0.0384 0.0383
Loa Loa (eye worm) TK/ALK protein kinase 0.0276 0.0667 0.0667
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0868 0.2518 0.5866
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.0173 0.0162
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0127 0.0202 0.0229
Schistosoma mansoni basigin related 0.0135 0.0225 0.0218
Brugia malayi Protein kinase domain 0.0086 0.0073 0.0073
Loa Loa (eye worm) protein kinase domain-containing protein 0.0209 0.0459 0.0459
Loa Loa (eye worm) TK/FER protein kinase 0.0393 0.1034 0.1034
Schistosoma mansoni tyrosine kinase 0.0594 0.1663 0.1656
Echinococcus granulosus raf serine:threonine protein kinase 0.0087 0.0077 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Entamoeba histolytica protein kinase, putative 0.0071 0.0027 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0572 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.0682 0.1936 0.193
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0868 0.2518 0.251
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0154 0.0287 0.0333
Plasmodium vivax unspecified product 0.01 0.0116 0.0076
Trypanosoma brucei casein kinase I, isoform 2 0.0108 0.0142 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0077 0.0069
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0143 0.0251 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0125 0.0196 0.0194
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.023 0.0525 0.0515
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0118 0.0108
Schistosoma mansoni cell adhesion molecule 0.0589 0.1646 0.164
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0173 0.0165
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.0577 0.0577
Trichomonas vaginalis CK1 family protein kinase 0.0108 0.0142 0.014
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0384 0.0382
Echinococcus multilocularis down syndrome cell adhesion 0.0113 0.0157 0.0149
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0151 0.0278 0.0321
Loa Loa (eye worm) hypothetical protein 0.0135 0.0226 0.0225
Loa Loa (eye worm) TK protein kinase 0.0341 0.0869 0.0869
Trypanosoma cruzi Protein kinase B 0.0163 0.0314 0.0368
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0059 0.0058
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0081 0.0057 0.0039
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Schistosoma mansoni notch 0.0253 0.0596 0.0589
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.0173 0.0165
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0093 0.0096 0.0089
Loa Loa (eye worm) animal heme peroxidase 0.0113 0.0157 0.0156
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0438 0.1172 0.1172
Onchocerca volvulus 0.0467 0.1266 0.1236
Entamoeba histolytica glycogenphosphorylase, putative 0.141 0.4213 0.4209
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0868 0.2518 0.3268
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0059 0.0058
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0353 0.0908 0.1149
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0158 0.0148
Brugia malayi Protein kinase domain containing protein 0.0344 0.0881 0.0881
Echinococcus multilocularis mitogen activated protein kinase 0.0084 0.0066 0.0059
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0868 0.2518 0.3248
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Echinococcus granulosus Immunoglobulin 0.0439 0.1178 0.1168
Echinococcus multilocularis c4b binding protein beta chain 0.0467 0.1266 0.1259
Onchocerca volvulus 0.0128 0.0204 0.0171
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0221 0.0497 0.0489
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0868 0.2518 0.3248
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0112 0.0155 0.0148
Brugia malayi Protein kinase domain containing protein 0.0584 0.1631 0.1631
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0225 0.0508 0.0498
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0135 0.0225 0.0218
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0066 0.0065
Loa Loa (eye worm) thioredoxin reductase 0.2505 0.7635 0.7635
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0247 0.0577 0.0577
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0247 0.0577 0.0577
Brugia malayi Protein kinase domain containing protein 0.0358 0.0924 0.0924
Schistosoma mansoni protein kinase 0.0423 0.1128 0.1121
Schistosoma mansoni hypothetical protein 0.0135 0.0225 0.0218
Schistosoma mansoni sodium/chloride dependent transporter 0.0089 0.0081 0.0074
Echinococcus granulosus down syndrome cell adhesion 0.0113 0.0157 0.0146
Schistosoma mansoni tyrosine kinase 0.0306 0.0761 0.0755
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.009 0.0085 0.0078
Brugia malayi STE20-like kinase MST 0.0252 0.0591 0.0591
Schistosoma mansoni protein kinase 0.0144 0.0253 0.0246
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0085 0.0069 0.0016
Schistosoma mansoni cell adhesion molecule 0.0135 0.0225 0.0218
Schistosoma mansoni tyrosine kinase 0.0221 0.0497 0.0489
Entamoeba histolytica thioredoxin reductase, putative 0.023 0.0525 0.0518
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0137 0.0234 0.0262
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0353 0.0908 0.1921
Schistosoma mansoni hemicentin 0.0128 0.0204 0.0197
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Loa Loa (eye worm) hypothetical protein 0.0574 0.1598 0.1598
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0093 0.0096 0.0089
Schistosoma mansoni protein kinase 0.0259 0.0615 0.0608
Echinococcus multilocularis casein kinase I delta 0.0108 0.0142 0.0134
Loa Loa (eye worm) hypothetical protein 0.0686 0.195 0.195
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0212 0.0467 0.046
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0144 0.0253 0.0243
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0135 0.0225 0.0215
Trichomonas vaginalis disulfide oxidoreductase, putative 0.023 0.0525 0.0524
Brugia malayi serine/threonine-protein kinase 6 0.0144 0.0253 0.0253
Echinococcus multilocularis protein jagged 1 0.0253 0.0596 0.0589
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0137 0.0234 0.0234
Schistosoma mansoni titin 0.0113 0.0157 0.0149
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0868 0.2518 1
Loa Loa (eye worm) hypothetical protein 0.0233 0.0532 0.0531
Mycobacterium ulcerans ferredoxin reductase 0.023 0.0525 0.1005
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0482 0.1311 0.1302
Schistosoma mansoni glutamate synthase 0.023 0.0525 0.0518
Echinococcus granulosus tyrosine protein kinase Srms 0.0494 0.135 0.1341
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0183 0.0376 0.0375
Echinococcus granulosus c-Jun N-terminal kinases 0.0259 0.0614 0.0604
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.0173 0.019
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0868 0.2518 0.3247
Echinococcus multilocularis glutamate synthase 0.023 0.0525 0.0518
Brugia malayi EGF-like domain containing protein 0.0253 0.0596 0.0596
Loa Loa (eye worm) hypothetical protein 0.0087 0.0075 0.0075
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0099 0.0114 0.0107
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0137 0.0234 0.0271
Loa Loa (eye worm) hypothetical protein 0.0448 0.1204 0.1203
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.01 0.0118 0.0079
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0368 0.0956 0.0954
Echinococcus multilocularis dual specificity 0.0121 0.0183 0.0176
Onchocerca volvulus 0.0099 0.0114 0.008
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0868 0.2518 0.2513
Loa Loa (eye worm) hypothetical protein 0.0347 0.0889 0.0889
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0111 0.0152 0.0155
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0118 0.0108
Loa Loa (eye worm) CDC7 protein kinase 0.009 0.0085 0.0084
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0089 0.0083 0.0034
Loa Loa (eye worm) hypothetical protein 0.023 0.0525 0.0525
Loa Loa (eye worm) hypothetical protein 0.044 0.1179 0.1179
Schistosoma mansoni hypothetical protein 0.0128 0.0204 0.0197
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0868 0.2518 0.5866
Schistosoma mansoni septate junction protein 0.0253 0.0596 0.0589
Giardia lamblia Kinase, CMGC CK2 0.01 0.0116 0.0052
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3248
Trichomonas vaginalis STE family protein kinase 0.0065 0.0007 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0322 0.0314
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0108 0.0142 0.0142
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0083 0.0019
Loa Loa (eye worm) solute carrier family 6 member 4 0.0089 0.0081 0.0081
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0112 0.0155 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0083 0.0076
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Echinococcus granulosus CDC7 cell division cycle 7 0.009 0.0085 0.0074
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0173 0.0165
Schistosoma mansoni notch 0.0253 0.0596 0.0589
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.01 0.0118 0.0079
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0184 0.0381 0.0371
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.012 0.018 0.0169
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.023 0.0525 0.0525
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0368 0.0956 0.0949
Schistosoma mansoni protein kinase 0.0358 0.0924 0.0917
Echinococcus multilocularis 0.0151 0.0277 0.0269
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0323 0.0815 0.0815
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0868 0.2518 0.2803
Giardia lamblia Kinase, AGC PKA 0.0112 0.0155 0.0091
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0159 0.0302 0.0291
Trichomonas vaginalis apoptosis inducing factor, putative 0.023 0.0525 0.0524
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0084 0.0066 0.0042
Toxoplasma gondii aurora kinase 0.0144 0.0253 0.0296
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0368 0.0956 0.0954
Loa Loa (eye worm) TK/INSR protein kinase 0.0437 0.117 0.117
Echinococcus granulosus neurogenic locus protein delta 0.0253 0.0596 0.0586
Echinococcus granulosus protein jagged 2 0.0253 0.0596 0.0586
Echinococcus granulosus NCK adaptor protein 0.009 0.0085 0.0074
Echinococcus granulosus casein kinase I delta 0.0108 0.0142 0.0131
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0262 0.0625 0.0618
Echinococcus multilocularis neural cadherin 0.0253 0.0596 0.0589
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0089 0.0083 0.0034
Toxoplasma gondii histone kinase SNF1, putative 0.0089 0.0083 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0083 0.0082
Echinococcus granulosus Down syndrome cell adhesion molecule 0.015 0.0273 0.0263
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0221 0.0497 0.0489
Echinococcus granulosus Immunoglobulin subtype 0.0135 0.0225 0.0215
Echinococcus granulosus roundabout 2 0.0262 0.0625 0.0615
Echinococcus multilocularis protein kinase shaggy 0.0127 0.0202 0.0195
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0868 0.2518 0.3248
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0265 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0467 0.1266 0.1265
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0868 0.2518 0.3248
Echinococcus granulosus serine/threonine protein kinase 0.0163 0.0314 0.0304
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.023 0.0525 0.1005
Echinococcus multilocularis N chimaerin 0.0093 0.0096 0.0089
Loa Loa (eye worm) hypothetical protein 0.0135 0.0225 0.0225
Echinococcus granulosus tyrosine protein kinase shark 0.0306 0.0761 0.0752
Loa Loa (eye worm) hypothetical protein 0.0455 0.1225 0.1225
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Plasmodium falciparum serine/threonine protein kinase KIN 0.0089 0.0083 0.0034
Trypanosoma brucei protein kinase, putative 0.0127 0.0202 0.0192
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0204 0.0204
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0157 0.0157
Giardia lamblia Kinase, PLK 0.0265 0.0632 0.0571
Trichomonas vaginalis glycogen phosphorylase, putative 0.3262 1 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.023 0.0525 0.0646
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.023 0.0525 0.0646
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0218 0.0486 0.0479
Onchocerca volvulus Putative titin 0.0113 0.0157 0.0123
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.019 0.0397 0.039
Echinococcus granulosus aurora kinase A 0.0144 0.0253 0.0243
Loa Loa (eye worm) TK/EGFR protein kinase 0.0594 0.1663 0.1662
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0108 0.0142 0.0141
Brugia malayi hypothetical protein 0.0218 0.0486 0.0486
Brugia malayi Myb-like DNA-binding domain containing protein 0.0113 0.0157 0.0157
Echinococcus multilocularis mitogen activated protein kinase 14 0.0157 0.0295 0.0288
Brugia malayi Temporarily assigned gene name protein 59 0.0108 0.0144 0.0144
Plasmodium vivax thioredoxin reductase, putative 0.2505 0.7635 1
Brugia malayi EGF-like domain containing protein 0.0253 0.0596 0.0596
Schistosoma mansoni kinase 0.0282 0.0688 0.0681
Brugia malayi Stress-activated protein kinase jnk-1 0.0259 0.0614 0.0614
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0154 0.0287 0.0277
Brugia malayi Cadherin domain containing protein 0.0253 0.0596 0.0596
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.019 0.0397 0.0397
Trypanosoma cruzi aurora B kinase, putative 0.0144 0.0253 0.0288
Giardia lamblia Kinase, NEK 0.0134 0.0225 0.0162
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0868 0.2518 0.2803
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0214 0.0472 0.0472
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0868 0.2518 0.2104
Echinococcus multilocularis tyrosine protein kinase Src42A 0.014 0.0242 0.0235
Echinococcus multilocularis roundabout 2 0.0262 0.0625 0.0618
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.023 0.0525 0.0525
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0127 0.0202 0.0195
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.01 0.0118 0.0079
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0111 0.0152 0.0125
Echinococcus granulosus basement membrane specific heparan sulfate 0.0135 0.0225 0.0215
Loa Loa (eye worm) hypothetical protein 0.0089 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0247 0.0577 0.0577
Schistosoma mansoni tyrosine kinase 0.0136 0.023 0.0223
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0253 0.0596 0.0589
Loa Loa (eye worm) TK/FER protein kinase 0.0099 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.03 0.0742 0.0742
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0184 0.0381 0.0374
Schistosoma mansoni hypothetical protein 0.0253 0.0596 0.0589
Brugia malayi serine/threonine-protein kinase PAK 7 0.0228 0.0516 0.0516
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.019 0.0397 0.039
Loa Loa (eye worm) CAMK protein kinase 0.0162 0.0312 0.0311
Onchocerca volvulus 0.0253 0.0596 0.0564
Echinococcus multilocularis protein kinase c epsilon type 0.0207 0.0452 0.0445
Trichomonas vaginalis CAMK family protein kinase 0.0213 0.047 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0385 0.1007 0.1001
Brugia malayi Disorganized muscle protein 1 0.0113 0.0157 0.0157
Echinococcus multilocularis protein jagged 1 0.0253 0.0596 0.0589
Schistosoma mansoni tyrosine kinase 0.0239 0.0551 0.0544
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0086 0.0073 0.0063
Echinococcus granulosus neurogenic locus notch protein 0.0253 0.0596 0.0586
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0083 0.0064 0.0009
Trichomonas vaginalis STE family protein kinase 0.0086 0.0073 0.0072
Trypanosoma brucei NADH dehydrogenase 0.023 0.0525 0.0617
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0135 0.0225 0.0218
Toxoplasma gondii EGF family domain-containing protein 0.0253 0.0596 0.0747
Echinococcus granulosus glutamate synthase 0.023 0.0525 0.0515
Loa Loa (eye worm) TK/EPH protein kinase 0.0126 0.0197 0.0197
Echinococcus granulosus tyrosine protein kinase Fyn 0.0221 0.0497 0.0486
Echinococcus granulosus serine threonine protein kinase nrc 0.0154 0.0287 0.0277
Plasmodium falciparum thioredoxin reductase 0.0868 0.2518 0.3248
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0155 0.0128
Onchocerca volvulus 0.0113 0.0157 0.0123
Brugia malayi hypothetical protein 0.0467 0.1266 0.1266
Onchocerca volvulus 0.0099 0.0114 0.008
Trypanosoma cruzi trypanothione reductase, putative 0.0868 0.2518 0.3268
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.019 0.0397 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0155 0.0148
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0154 0.0287 0.0303
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0868 0.2518 0.3268
Brugia malayi Tyrosine-protein kinase abl-1 0.0136 0.023 0.023
Echinococcus multilocularis neurogenic locus protein delta 0.0253 0.0596 0.0589
Schistosoma mansoni glutamate synthase 0.023 0.0525 0.0518
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0112 0.0155 0.0159
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0089 0.0083 0.0065
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.023 0.0525 0.0617
Loa Loa (eye worm) hypothetical protein 0.0112 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0135 0.0226 0.0225
Trichomonas vaginalis CMGC family protein kinase 0.0084 0.0066 0.0065
Echinococcus multilocularis serine:threonine protein kinase N2 0.0291 0.0715 0.0708
Loa Loa (eye worm) hypothetical protein 0.0253 0.0596 0.0596
Echinococcus granulosus neuroglian 0.0552 0.153 0.1521
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0234 0.0232
Onchocerca volvulus 0.023 0.0525 0.0493
Echinococcus multilocularis rho associated protein kinase 0.0318 0.0798 0.0791
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.023 0.0525 0.0617
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.0173 0.0165
Schistosoma mansoni sulfide quinone reductase 0.023 0.0525 0.0518
Brugia malayi Calcium binding EGF domain containing protein 0.0253 0.0596 0.0596
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0632 0.063
Brugia malayi Casein kinase II, alpha chain 0.01 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.0121 0.0183 0.0176
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0313 0.0313
Brugia malayi glutamate synthase 0.023 0.0525 0.0525

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 0.17 mg kg-1 Effective dose of the compound for PCA-induced 5-HT depletion was determined by subcutaneous administration ChEMBL. 15771448
ED50 (functional) = 0.39 mg kg-1 Effective dose concentration of the compound for antagonism ofpCA-Induced excitation was determined by subcutaneous administration ChEMBL. 15771448
ED50 (functional) = 0.63 mg kg-1 Effective dose for reversal of medetomidine-induced loss of righting by subcutaneous administration ChEMBL. 15771448
ED50 (functional) = 1.1 mg kg-1 Effective dose of the compound for PCA-induced 5-HT depletion was determined by oral administration ChEMBL. 15771448
ED50 (functional) = 1.3 mg kg-1 Effective dose of the compound for reversal of medetomidine-Induced loss of righting was determined by oral administration ChEMBL. 15771448
ED50 (functional) = 5 mg kg-1 Effective dose of the compound for antagonism ofpCA-Induced excitation was determined by oral administration ChEMBL. 15771448
Ki (binding) = 0.5 nM Inhibition of [3H]- rauwolscine binding to alpha-2C adrenergic receptor ChEMBL. 15771448
Ki (binding) = 1.2 nM Inhibition of [3H]- paroxetine binding to 5-HTT receptor, serotonin transporter ChEMBL. 15771448
Ki (binding) = 2.6 nM Inhibition of [3H]- rauwolscine binding to human alpha-2A adrenergic receptor ChEMBL. 15771448
Ki (functional) = 6.2 nM Binding affinity for alpha-2C adrenergic receptor ChEMBL. 15771448
Ki (functional) = 8.3 nM Binding affinity for serotonin transporter ChEMBL. 15771448
Ki (functional) = 8.8 nM Binding affinity for Alpha-2C adrenergic receptor ChEMBL. 15771448
Ki (binding) = 14 nM Inhibition of [3H]- rauwolscine binding to alpha-2B adrenergic receptor ChEMBL. 15771448
Ki (binding) = 270 nM Inhibition of [125I]-iodosulpride binding to Dopamine receptor D3 ChEMBL. 15771448
Ki (binding) = 312 nM Inhibition of [3H]-nisoxetine binding to Norepinephrin transporter from rat cortex ChEMBL. 15771448
Ki (binding) = 515 nM Inhibition of [3H]-WIN-35,428 binding to Dopamine transporter of rat striatum ChEMBL. 15771448
Ki (binding) = 959 nM Inhibition of [3H]-spiperone binding to Dopamine receptor D2 ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [3H]-5-HT binding to 5-hydroxytryptamine 7 receptor ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [3H]-pyrilamine binding to Histamine H1 receptor ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [3H]-spiperone binding to Dopamine receptor D4 ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [3H]- prazosin binding to alpha-1 adrenergic receptor ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [125I]- R91150 binding to 5-hydroxytryptamine 2A receptor ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [3H]- mesulergine binding to 5-hydroxytryptamine 2C receptor ChEMBL. 15771448
Ki (binding) > 1000 nM Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor ChEMBL. 15771448

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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