Detailed information for compound 312532

Basic information

Technical information
  • TDR Targets ID: 312532
  • Name: 5-chloro-3-(3,5-dimethylphenyl)sulfonyl-N'-(2 -hydroxyethyl)-1H-indole-2-carbohydrazide
  • MW: 421.898 | Formula: C19H20ClN3O4S
  • H donors: 4 H acceptors: 4 LogP: 2.89 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCNNC(=O)c1[nH]c2c(c1S(=O)(=O)c1cc(C)cc(c1)C)cc(cc2)Cl
  • InChi: 1S/C19H20ClN3O4S/c1-11-7-12(2)9-14(8-11)28(26,27)18-15-10-13(20)3-4-16(15)22-17(18)19(25)23-21-5-6-24/h3-4,7-10,21-22,24H,5-6H2,1-2H3,(H,23,25)
  • InChiKey: XAOANWPRTZIZKN-UHFFFAOYSA-N  

Network

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Synonyms

  • 1H-Indole-2-carboxylic acid, 5-chloro-3-[(3,5-dimethylphenyl)sulfonyl]-, 2-(2-hydroxyethyl)hydrazide
  • AIDS-184629
  • AIDS184629

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0195 0.0239 0.0239
Plasmodium falciparum casein kinase 1 0.0228 0.0359 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0359 0.0359
Giardia lamblia Kinase, STE STE20 0.0181 0.0188 0.0073
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0181 0.0188 0.0188
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0177 0.0175 0.0175
Echinococcus granulosus calcium activated potassium channel 0.0283 0.0557 0.0557
Brugia malayi Delta serrate ligand family protein 0.0293 0.0593 0.0593
Trypanosoma cruzi aurora B kinase, putative 0.0247 0.0427 0.0396
Schistosoma mansoni slit 0.0141 0.0044 0.0044
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0293 0.0593 0.2188
Brugia malayi putative serine/threonine kinase SADA gamma 0.0164 0.0129 0.0129
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0766 0.2302 0.7262
Echinococcus granulosus tyrosine protein kinase Fyn 0.032 0.0692 0.0692
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0141 0.0044 0.0044
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Echinococcus granulosus twitchin 0.0763 0.2292 0.2292
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0159 0.011 0.011
Plasmodium falciparum protein kinase 5 0.0249 0.0436 0.0404
Brugia malayi kettin 0.014 0.0042 0.0042
Echinococcus multilocularis mitogen activated protein kinase 0.0176 0.0171 0.0171
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0766 0.2302 0.2302
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0228 0.0359 0.0327
Loa Loa (eye worm) AGC/PKG protein kinase 0.0177 0.0175 0.0175
Trypanosoma cruzi casein kinase, putative 0.0228 0.0359 0.0327
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0166 0.0134 0.0134
Schistosoma mansoni tyrosine kinase 0.0197 0.0246 0.0246
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0498 0.1511
Entamoeba histolytica protein kinase , putative 0.0247 0.0427 0.1462
Onchocerca volvulus 0.014 0.0042 0.0095
Echinococcus multilocularis c4b binding protein beta chain 0.054 0.1488 0.1488
Toxoplasma gondii rhoptry neck protein RON9 0.054 0.1488 0.146
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Brugia malayi Serine/threonine-protein kinase SULU 0.0465 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.029 0.0585 0.0585
Loa Loa (eye worm) TK protein kinase 0.0261 0.0477 0.0477
Echinococcus granulosus protein tyrosine kinase 0.0603 0.1715 0.1715
Echinococcus multilocularis rho associated protein kinase 0.0681 0.1996 0.1996
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0465 0.1218 0.1218
Echinococcus multilocularis tyrosine protein kinase Src64B 0.032 0.0692 0.0692
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0266 0.0498 0.0467
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Echinococcus multilocularis titin 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0234 0.0381 0.0381
Plasmodium falciparum glutathione reductase 0.2895 1 1
Loa Loa (eye worm) programmed cell death 8 0.0266 0.0498 0.0498
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0157 0.0102 0.0102
Echinococcus multilocularis cyclin 0.0886 0.2736 0.2736
Schistosoma mansoni serine/threonine protein kinase 0.0534 0.1466 0.1466
Giardia lamblia High cysteine protein 0.0293 0.0593 0.1425
Schistosoma mansoni tyrosine kinase 0.032 0.0692 0.0692
Giardia lamblia Glutamate synthase 0.0266 0.0498 0.1109
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0553 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.0159 0.011 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0266 0.0498 0.1719
Schistosoma mansoni rap gtpase-activating protein 0.0234 0.0381 0.0381
Echinococcus granulosus mitogen activated protein kinase 11 0.0333 0.0741 0.0741
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0166 0.0134 0.0134
Echinococcus multilocularis C type lectin domian containing protein 0.054 0.1488 0.1488
Trypanosoma brucei rac serine-threonine kinase, putative 0.0612 0.1747 0.172
Loa Loa (eye worm) CAMK protein kinase 0.0229 0.0362 0.0362
Brugia malayi Immunoglobulin I-set domain containing protein 0.0325 0.0709 0.0709
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2895 1 1
Schistosoma mansoni tyrosine kinase 0.0629 0.1808 0.1808
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0212 0.03 0.0268
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0908 0.2819 0.2819
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0498 0.0467
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0425 0.107 0.107
Echinococcus granulosus Immunoglobulin subtype 0.0166 0.0134 0.0134
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Echinococcus granulosus titin 0.014 0.0042 0.0042
Schistosoma mansoni septate junction protein 0.0166 0.0134 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0354 0.0816 0.2526
Plasmodium vivax serine/threonine kinase-1, putative 0.0322 0.0699 0.0558
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0322 0.0699 0.0669
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0325 0.0709 0.0709
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0452 0.1171 0.1171
Echinococcus granulosus serine:threonine kinase SAD 1 0.0164 0.0129 0.0129
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0421 0.1056 0.1056
Schistosoma mansoni kinase 0.0167 0.0138 0.0138
Brugia malayi Cam kinase protein 1 0.0212 0.03 0.03
Brugia malayi Protein kinase domain containing protein 0.0318 0.0685 0.0685
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1581 0.4963
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0171 0.0171
Echinococcus granulosus NDR protein kinase 0.0337 0.0755 0.0755
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Schistosoma mansoni notch 0.0293 0.0593 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Schistosoma mansoni tyrosine kinase 0.0363 0.0847 0.0847
Brugia malayi Temporarily assigned gene name protein 59 0.027 0.0511 0.0511
Echinococcus multilocularis activin receptor type 0.0138 0.0033 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.011 0.011
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Schistosoma mansoni serine/threonine kinase 0.0472 0.124 0.124
Echinococcus multilocularis casein kinase I gamma 0.0447 0.115 0.115
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0256 0.0462 0.0431
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0266 0.0498 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1315 0.1315
Trichomonas vaginalis CMGC family protein kinase 0.027 0.051 0.1551
Brugia malayi Heparan sulfate 0.0166 0.0134 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0359 0.0833 0.2579
Loa Loa (eye worm) hypothetical protein 0.029 0.0585 0.0585
Schistosoma mansoni basigin related 0.0166 0.0134 0.0134
Trichomonas vaginalis STE family protein kinase 0.0181 0.0188 0.0523
Onchocerca volvulus 0.0681 0.1996 0.752
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0303 0.0632 0.0632
Schistosoma mansoni hypothetical protein 0.014 0.0042 0.0042
Schistosoma mansoni septate junction protein 0.0306 0.064 0.064
Giardia lamblia Aurora kinase 0.0247 0.0427 0.0872
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0164 0.0129 0.0097
Brugia malayi Protein kinase domain containing protein 0.0404 0.0995 0.0995
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0139 0.0036 0.0046
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0129 0.0129
Echinococcus multilocularis calcium activated potassium channel 0.0283 0.0557 0.0557
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0766 0.2302 0.2302
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Loa Loa (eye worm) projectin 0.0159 0.011 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Brugia malayi Hr1 repeat family protein 0.0609 0.1735 0.1735
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0768 0.2311 0.2311
Brugia malayi Prion-like- 0.014 0.0042 0.0042
Plasmodium falciparum dihydroorotate dehydrogenase 0.1279 0.4157 0.4137
Entamoeba histolytica PH domain containing protein kinase, putative 0.0344 0.0779 0.2738
Loa Loa (eye worm) TK protein kinase 0.0191 0.0227 0.0227
Echinococcus multilocularis dual specificity 0.0291 0.0588 0.0588
Toxoplasma gondii selenide, water dikinase 0.0266 0.0498 0.0467
Echinococcus multilocularis peroxidasin 0.0306 0.0642 0.0642
Schistosoma mansoni serine/threonine protein kinase 0.0513 0.1391 0.1391
Echinococcus multilocularis twitchin 0.021 0.0293 0.0293
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0557 0.0557
Trypanosoma cruzi cdc2-related kinase 3 0.0249 0.0436 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.1171 0.1171
Trypanosoma brucei cdc2-related kinase 3 0.0249 0.0436 0.0404
Trichomonas vaginalis CMGC family protein kinase 0.027 0.051 0.1551
Schistosoma mansoni roundabout 0.0306 0.064 0.064
Brugia malayi Prion-like- 0.014 0.0042 0.0042
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0237 0.0392 0.0361
Giardia lamblia Kinase, NEK 0.0285 0.0567 0.1339
Echinococcus multilocularis tyrosine protein kinase Src42A 0.032 0.0692 0.0692
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0137 0.0031 0.0027
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.014 0.0042 0.0042
Brugia malayi Protein kinase domain containing protein 0.0455 0.1178 0.1178
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0175 0.0175
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0266 0.0498 0.0498
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0456 0.1183 0.1183
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0825 0.2518 0.2518
Brugia malayi Protein kinase domain containing protein 0.1971 0.6661 0.6661
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0164 0.0129 0.0129
Echinococcus multilocularis casein kinase I alpha 0.0228 0.0359 0.0359
Schistosoma mansoni cell adhesion molecule 0.0166 0.0134 0.0134
Brugia malayi Leucine Rich Repeat family protein 0.0141 0.0044 0.0044
Entamoeba histolytica cell division protein kinase 2, putative 0.0266 0.0497 0.1717
Brugia malayi EGF-like domain containing protein 0.0293 0.0593 0.0593
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0425 0.107 0.107
Echinococcus multilocularis 0.0253 0.0448 0.0448
Schistosoma mansoni cell adhesion molecule 0.0325 0.0709 0.0709
Echinococcus granulosus Vam6:Vps39 protein 0.0234 0.0381 0.0381
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0266 0.0498 0.0467
Entamoeba histolytica protein kinase domain containing protein 0.0167 0.0138 0.0413
Brugia malayi Calcium binding EGF domain containing protein 0.0293 0.0593 0.0593
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0174 0.0166 0.0134
Echinococcus multilocularis Immunoglobulin 0.0553 0.1535 0.1535
Brugia malayi Cadherin domain containing protein 0.0293 0.0593 0.0593
Echinococcus granulosus N chimaerin 0.0157 0.0102 0.0102
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0498 0.0467
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0492 0.1315 0.1315
Loa Loa (eye worm) hypothetical protein 0.0306 0.064 0.064
Trypanosoma cruzi casein kinase, putative 0.0228 0.0359 0.0327
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.032 0.0692 0.0692
Echinococcus granulosus tyrosine protein kinase Blk 0.0261 0.0477 0.0477
Schistosoma mansoni hypothetical protein 0.0166 0.0134 0.0134
Echinococcus granulosus delta-like protein 1 0.0293 0.0593 0.0593
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0247 0.0427 0.1462
Schistosoma mansoni nephrin related 0.0166 0.0134 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0588 0.0588
Giardia lamblia Kinase, STE STE20 0.0178 0.0178 0.0039
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0566 0.1581 0.1581
Echinococcus granulosus serine:threonine protein kinase 0.0239 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.0239 0.04 0.04
Onchocerca volvulus Netrin receptor homolog 0.0201 0.026 0.0925
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0168 0.0141 0.0141
Echinococcus granulosus titin 0.0229 0.0362 0.0362
Echinococcus multilocularis aurora kinase A 0.0247 0.0427 0.0427
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Brugia malayi P38 map kinase family protein 2 0.0333 0.0741 0.0741
Echinococcus multilocularis thioredoxin glutathione reductase 0.2895 1 1
Leishmania major protein kinase, putative 0.0247 0.0427 0.0396
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0322 0.0699 0.0669
Echinococcus granulosus neuroglian 0.0693 0.2041 0.2041
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0247 0.0427 0.1462
Schistosoma mansoni septate junction protein 0.0293 0.0593 0.0593
Echinococcus granulosus epidermal growth factor receptor 0.0506 0.1365 0.1365
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.1279 0.4157 1
Echinococcus granulosus titin 0.014 0.0042 0.0042
Plasmodium falciparum calcium-dependent protein kinase 3 0.0212 0.03 0.0268
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0249 0.0435 0.0435
Trichomonas vaginalis CMGC family protein kinase 0.0176 0.0171 0.0468
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0176 0.0171 0.0138
Brugia malayi Immunoglobulin domain containing protein 0.0166 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0166 0.0134 0.0134
Trypanosoma cruzi casein kinase, putative 0.0228 0.0359 0.0327
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0164 0.0129 0.0097
Echinococcus multilocularis tyrosine protein kinase Srms 0.0261 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.0212 0.03 0.03
Schistosoma mansoni tyrosine kinase 0.0134 0.0019 0.0019
Toxoplasma gondii thioredoxin reductase 0.2895 1 1
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0596 0.169 0.169
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.021 0.0294 0.0294
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0181 0.0188 0.0188
Echinococcus granulosus cyclin 0.0886 0.2736 0.2736
Loa Loa (eye worm) hypothetical protein 0.029 0.0585 0.0585
Entamoeba histolytica disulphide oxidoreductase, putative 0.0266 0.0498 0.1719
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0321 0.0695 0.0695
Echinococcus granulosus mitogen activated protein kinase 0.0176 0.0171 0.0171
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0176 0.0171 0.0138
Loa Loa (eye worm) hypothetical protein 0.0166 0.0134 0.0134
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0237 0.0392 0.0392
Brugia malayi Casein kinase II, alpha chain 0.021 0.0294 0.0294
Onchocerca volvulus Serine\/threonine kinase homolog 0.0344 0.0778 0.2893
Schistosoma mansoni protein kinase 0.0181 0.0188 0.0188
Echinococcus granulosus Protein kinase C brain isozyme 0.0511 0.1381 0.1381
Brugia malayi Protein kinase domain containing protein 0.0137 0.0031 0.0031
Brugia malayi SH2 domain containing protein 0.0458 0.119 0.119
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0325 0.0709 0.0709
Brugia malayi basement membrane proteoglycan precursor 0.0166 0.0134 0.0134
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0908 0.2819 0.2819
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0185 0.0203 0.0203
Loa Loa (eye worm) glutathione reductase 0.2895 1 1
Schistosoma mansoni hypothetical protein 0.0234 0.0381 0.0381
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0247 0.0427 0.0427
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0266 0.0498 0.0467
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0266 0.0498 0.0498
Giardia lamblia Kinase, NEK 0.0285 0.0567 0.1339
Echinococcus multilocularis tyrosine protein kinase HCK 0.0191 0.0227 0.0227
Schistosoma mansoni tyrosine kinase 0.0629 0.1808 0.1808
Onchocerca volvulus 0.054 0.1488 0.5589
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0256 0.0462 0.0431
Trypanosoma cruzi trypanothione reductase, putative 0.2895 1 1
Schistosoma mansoni hypothetical protein 0.014 0.0042 0.0042
Echinococcus multilocularis down syndrome cell adhesion 0.014 0.0042 0.0042
Echinococcus multilocularis netrin receptor unc 5 0.0226 0.0353 0.0353
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0167 0.0138 0.0138
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0737 0.2199 0.2199
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0185 0.0203 0.0203
Schistosoma mansoni tyrosine kinase 0.0374 0.0886 0.0886
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0233 0.0233
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Echinococcus multilocularis cyclin dependent kinase 1 0.0249 0.0436 0.0436
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Onchocerca volvulus 0.0293 0.0593 0.2188
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0303 0.0632 0.0632
Echinococcus multilocularis 0.0201 0.0263 0.0263
Echinococcus granulosus dual specificity protein kinase clk2 0.0322 0.0699 0.0699
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0241 0.0408 0.0408
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0421 0.1055 0.1055
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0337 0.0755 0.0755
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0738 0.2204 0.2204
Onchocerca volvulus 0.0137 0.0031 0.0055
Trichomonas vaginalis glutamate synthase, putative 0.0266 0.0498 0.1511
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Brugia malayi protein-tyrosine kinase 0.0261 0.0477 0.0477
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0538 0.148 0.148
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1581 0.4963
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0337 0.0755 0.0755
Toxoplasma gondii CMGC kinase, CK2 family 0.021 0.0294 0.0263
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0325 0.0709 0.0709
Schistosoma mansoni hypothetical protein 0.014 0.0042 0.0042
Brugia malayi Protein kinase domain containing protein 0.0322 0.0699 0.0699
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Echinococcus multilocularis roundabout 2 0.0325 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.039 0.0944 0.0944
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Plasmodium falciparum serine/threonine protein kinase 0.0174 0.0166 0.0134
Trichomonas vaginalis CAMK family protein kinase 0.0455 0.1178 0.3679
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0328 0.0722 0.0581
Loa Loa (eye worm) SRC-1 0.032 0.0692 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0681 0.1996 0.1996
Schistosoma mansoni laminin gamma-3 chain 0.0293 0.0593 0.0593
Onchocerca volvulus 0.054 0.1488 0.5589
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0245 0.0423 0.0423
Schistosoma mansoni basigin related 0.0166 0.0134 0.0134
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1003 0.3162 0.7281
Trichomonas vaginalis STE family protein kinase 0.0285 0.0567 0.1731
Echinococcus multilocularis titin 0.014 0.0042 0.0042
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.014 0.0042 0.0042
Trichomonas vaginalis STE family protein kinase 0.0178 0.0178 0.049
Echinococcus granulosus titin 0.0229 0.0362 0.0362
Echinococcus granulosus insulin receptor 0.0629 0.1808 0.1808
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0499 0.134 0.1312
Echinococcus granulosus dual specificity 0.0291 0.0588 0.0588
Echinococcus multilocularis neural cadherin 0.0293 0.0593 0.0593
Echinococcus granulosus serine:threonine protein kinase 3 0.0538 0.148 0.148
Echinococcus multilocularis Immunoglobulin 0.0166 0.0134 0.0134
Echinococcus granulosus tyrosine protein kinase otk 0.0306 0.064 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0755 0.0755
Loa Loa (eye worm) hypothetical protein 0.022 0.0331 0.0331
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0176 0.0171 0.0138
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0394 0.096 0.096
Echinococcus multilocularis tyrosine protein kinase Blk 0.0261 0.0477 0.0477
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0129 0.0129
Entamoeba histolytica protein kinase, putative 0.0612 0.1747 0.6249
Leishmania major protein kinase, putative 0.0178 0.0178 0.0145
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1003 0.3162 0.3139
Brugia malayi Cyclin C 0.177 0.5933 0.5933
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1035 0.3276 0.3276
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Schistosoma mansoni tyrosine kinase 0.032 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.0554 0.1537 0.1537
Echinococcus granulosus neuroglian 0.0325 0.0709 0.0709
Onchocerca volvulus 0.0159 0.011 0.0356
Trypanosoma cruzi NADH dehydrogenase, putative 0.0266 0.0498 0.0467
Schistosoma mansoni hypothetical protein 0.0266 0.0498 0.0498
Brugia malayi Sushi domain 0.054 0.1488 0.1488
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Echinococcus granulosus low density lipoprotein receptor ldl 0.0166 0.0134 0.0134
Echinococcus granulosus leucine rich repeat containing protein 4 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Plasmodium falciparum serine/threonine protein kinase KIN 0.0164 0.0129 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0557 0.0557
Echinococcus multilocularis hemicentin 1 0.0306 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Onchocerca volvulus 0.0228 0.0359 0.1301
Echinococcus granulosus c4b binding protein beta chain 0.054 0.1488 0.1488
Echinococcus granulosus peroxidasin 0.0306 0.0642 0.0642
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0266 0.0497 0.0497
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.027 0.051 0.0479
Echinococcus granulosus dual specificity 0.0291 0.0588 0.0588
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0557 0.0557
Echinococcus granulosus aurora kinase A 0.0247 0.0427 0.0427
Entamoeba histolytica protein kinase, putative 0.0612 0.1747 0.6249
Echinococcus multilocularis insulin growth factor binding 0.014 0.0042 0.0042
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0234 0.0381 0.0381
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0293 0.0593 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Schistosoma mansoni protein kinase 0.0321 0.0695 0.0695
Onchocerca volvulus Putative titin 0.014 0.0042 0.0095
Echinococcus multilocularis mitogen activated protein kinase 14 0.0333 0.0741 0.0741
Schistosoma mansoni netrin receptor unc5 0.0226 0.0353 0.0353
Schistosoma mansoni tyrosine kinase 0.038 0.091 0.091
Echinococcus multilocularis protein kinase c epsilon type 0.0428 0.1081 0.1081
Brugia malayi protein kinase C II. 0.0428 0.1081 0.1081
Loa Loa (eye worm) hypothetical protein 0.0159 0.011 0.011
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Schistosoma mansoni tyrosine kinase 0.0197 0.0246 0.0246
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.017 0.015 0.0118
Brugia malayi Protein kinase domain containing protein 0.0359 0.0833 0.0833
Schistosoma mansoni ephrin receptor 0.0202 0.0266 0.0266
Echinococcus multilocularis cyclin dependent kinase 1 0.0249 0.0436 0.0436
Echinococcus granulosus C type lectin domian containing protein 0.054 0.1488 0.1488
Trypanosoma cruzi cdc2-related kinase 3 0.0249 0.0436 0.0404
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0181 0.0188 0.0188
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0325 0.0709 0.0709
Brugia malayi Calcium binding EGF domain containing protein 0.0293 0.0593 0.0593
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0237 0.0392 0.0361
Entamoeba histolytica protein kinase, putative 0.0191 0.0227 0.0738
Echinococcus granulosus dual specificity 0.0256 0.0462 0.0462
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0322 0.0699 0.0669
Leishmania major trypanothione reductase 0.2895 1 1
Schistosoma mansoni tyrosine kinase 0.0294 0.0597 0.0597
Treponema pallidum NADH oxidase 0.1003 0.3162 1
Trichomonas vaginalis AGC family protein kinase 0.0188 0.0215 0.0609
Loa Loa (eye worm) hypothetical protein 0.0572 0.1604 0.1604
Schistosoma mansoni tyrosine kinase 0.0421 0.1058 0.1058
Loa Loa (eye worm) AGC/PKA protein kinase 0.0237 0.0392 0.0392
Loa Loa (eye worm) AGC/AKT protein kinase 0.0612 0.1747 0.1747
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1581 0.4963
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.03 0.03
Echinococcus granulosus roundabout 2 0.0325 0.0709 0.0709
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0506 0.1365 0.1365
Echinococcus multilocularis serine:threonine protein kinase 0.0239 0.04 0.04
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0216 0.0613
Echinococcus granulosus roundabout 2 0.0878 0.2709 0.2709
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0266 0.0498 0.0467
Plasmodium vivax ferrodoxin reductase, putative 0.0266 0.0498 0.0353
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0174 0.0166 0.0166
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0234 0.0381 0.0381
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0738 0.2204 0.2204
Echinococcus multilocularis raf serine:threonine protein kinase 0.0156 0.0098 0.0098
Trichomonas vaginalis STE family protein kinase 0.0181 0.0188 0.0523
Echinococcus granulosus mitogen activated protein kinase 3 0.0176 0.0171 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0436 0.0436
Echinococcus granulosus mitogen activated protein kinase 14 0.0333 0.0741 0.0741
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.027 0.051 0.0479
Toxoplasma gondii EGF family domain-containing protein 0.0293 0.0593 0.0562
Onchocerca volvulus 0.0293 0.0593 0.2188
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0212 0.03 0.03
Trypanosoma brucei Casein kinase II 0.021 0.0294 0.0263
Plasmodium vivax protein kinase Crk2 0.0249 0.0436 0.029
Echinococcus granulosus calcium dependent protein kinase 0.0142 0.0049 0.0049
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0181 0.0188 0.0188
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0166 0.0134 0.0134
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0322 0.0699 0.0669
Echinococcus granulosus casein kinase I alpha 0.0228 0.0359 0.0359
Onchocerca volvulus 0.0137 0.0031 0.0055
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0458 0.119 0.119
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0174 0.0166 0.0134
Brugia malayi notch-like transmembrane receptor 0.0293 0.0593 0.0593
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0266 0.0498 0.0353
Entamoeba histolytica PH domain containing protein kinase, putative 0.0344 0.0779 0.2738
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0247 0.0427 0.1462
Echinococcus multilocularis slit 2 protein 0.0339 0.0761 0.0761
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Leishmania major protein kinase A catalytic subunit isoform 2 0.0237 0.0392 0.0361
Brugia malayi Disorganized muscle protein 1 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Loa Loa (eye worm) LAD-2 short isoform 0.0166 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0253 0.0452 0.0452
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.054 0.1488 0.1488
Brugia malayi Protein kinase domain containing protein 0.0249 0.0436 0.0436
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0237 0.0392 0.0361
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0737 0.2199 0.2199
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0266 0.0498 0.0498
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0322 0.0699 0.0699
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0291 0.0588 0.0558
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1003 0.3162 0.3139
Giardia lamblia Kinase, AGC PKA 0.0328 0.0722 0.1856
Brugia malayi Doublecortin family protein 0.0316 0.0678 0.0678
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0886 0.2736 0.2736
Onchocerca volvulus Slit protein homolog 0.0339 0.0761 0.2826
Schistosoma mansoni cell adhesion molecule 0.014 0.0042 0.0042
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0181 0.0188 0.0188
Toxoplasma gondii rhoptry neck protein RON1 0.054 0.1488 0.146
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0266 0.0498 0.0467
Echinococcus granulosus nervana 2 0.0259 0.0471 0.0471
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0285 0.0567 0.0536
Trichomonas vaginalis apoptosis inducing factor, putative 0.0266 0.0498 0.1511
Onchocerca volvulus 0.0234 0.0381 0.1382
Echinococcus multilocularis death associated protein kinase 1 0.0931 0.2902 0.2902
Plasmodium vivax glycogen synthase kinase 3, putative 0.027 0.051 0.0366
Schistosoma mansoni cell adhesion molecule 0.0159 0.011 0.011
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0316 0.0678 0.0678
Echinococcus granulosus casein kinase I delta 0.0228 0.0359 0.0359
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0166 0.0134 0.0134
Onchocerca volvulus 0.0158 0.0108 0.0346
Onchocerca volvulus 0.0137 0.0031 0.0055
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1003 0.3162 0.3139
Trichomonas vaginalis STE family protein kinase 0.0181 0.0188 0.0523
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0436 0.1313
Schistosoma mansoni titin 0.0306 0.064 0.064
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0337 0.0755 0.0755
Echinococcus granulosus c src tyrosine kinase 0.0197 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Entamoeba histolytica protein kinase, putative 0.0291 0.0588 0.2047
Brugia malayi Prion-like- 0.014 0.0042 0.0042
Onchocerca volvulus 0.014 0.0042 0.0095
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0306 0.064 0.064
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Entamoeba histolytica protein kinase, putative 0.0174 0.0166 0.0515
Brugia malayi Protein kinase domain containing protein 0.0738 0.2204 0.2204
Schistosoma mansoni vav2 0.0172 0.0159 0.0159
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1003 0.3162 0.3139
Giardia lamblia Kinase, CMGC GSK 0.027 0.051 0.115
Loa Loa (eye worm) Notch2 0.0293 0.0593 0.0593
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0164 0.0129 0.0097
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0566 0.1581 0.1554
Echinococcus granulosus netrin receptor unc 5 0.0226 0.0353 0.0353
Leishmania major NADH dehydrogenase, putative 0.0266 0.0498 0.0467
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0325 0.0709 0.0709
Trypanosoma cruzi hypothetical protein, conserved 0.0266 0.0498 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0427 0.0427
Schistosoma mansoni titin 0.014 0.0042 0.0042
Loa Loa (eye worm) AGC/PKA protein kinase 0.0237 0.0392 0.0392
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0259 0.0471 0.0471
Leishmania major dihydroorotate dehydrogenase 0.1279 0.4157 0.4137
Schistosoma mansoni hypothetical protein 0.014 0.0042 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0833 0.2545 0.2545
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0513 0.1391 0.1391
Echinococcus granulosus tyrosine protein kinase Srms 0.0568 0.1589 0.1589
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Schistosoma mansoni tyrosine kinase 0.0726 0.2161 0.2161
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Brugia malayi Protein kinase domain containing protein 0.119 0.3836 0.3836
Loa Loa (eye worm) AGC/PKN protein kinase 0.0609 0.1735 0.1735
Echinococcus granulosus serine:threonine protein kinase N2 0.0271 0.0516 0.0516
Echinococcus granulosus cyclin dependent kinase 19 0.119 0.3836 0.3836
Echinococcus multilocularis epidermal growth factor receptor 0.0726 0.2161 0.2161
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0237 0.0392 0.0361
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0155 0.0096 0.0096
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.021 0.0294 0.0147
Brugia malayi EGF-like domain containing protein 0.0293 0.0593 0.0593
Echinococcus granulosus c-Jun N-terminal kinases 0.0553 0.1536 0.1536
Echinococcus multilocularis dual specificity 0.0291 0.0588 0.0588
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0306 0.064 0.064
Echinococcus multilocularis neuroglian 0.0693 0.2041 0.2041
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0266 0.0498 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Schistosoma mansoni dihydroorotate dehydrogenase 0.1279 0.4157 0.4157
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0234 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0965 0.3025 0.3025
Onchocerca volvulus 0.0293 0.0593 0.2188
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.0778 0.0778
Echinococcus multilocularis transfer RNA-Phe 0.0159 0.011 0.011
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1003 0.3162 0.2803
Trichomonas vaginalis CMGC family protein kinase 0.0291 0.0588 0.1799
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0465 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.0166 0.0134 0.0134
Brugia malayi Cyclin, N-terminal domain containing protein 0.0886 0.2736 0.2736
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0157 0.0102 0.0102
Trypanosoma cruzi NADH dehydrogenase, putative 0.0266 0.0498 0.0467
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.032 0.0692 0.0692
Brugia malayi Protein kinase domain containing protein 0.0447 0.115 0.115
Echinococcus granulosus roundabout 2 0.0325 0.0709 0.0709
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0709 0.2097 0.2097
Plasmodium vivax glutathione reductase, putative 0.2895 1 1
Schistosoma mansoni glutamate synthase 0.0266 0.0498 0.0498
Brugia malayi Egg laying defective protein 4 0.0177 0.0175 0.0175
Echinococcus multilocularis fibropellin Ia 0.0293 0.0593 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0212 0.03 0.088
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.119 0.3836 0.3836
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0306 0.064 0.064
Schistosoma mansoni nephrin 0.0712 0.211 0.211
Echinococcus multilocularis Immunoglobulin 0.0166 0.0134 0.0134
Brugia malayi Furin-like cysteine rich region family protein 0.0726 0.2161 0.2161
Echinococcus granulosus fibroblast growth factor receptor 4 0.038 0.091 0.091
Brugia malayi EGF-like domain containing protein 0.0339 0.0761 0.0761
Echinococcus granulosus cGMP dependent protein kinase 1 0.0177 0.0175 0.0175
Entamoeba histolytica protein kinase, putative 0.0256 0.0462 0.1588
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0239 0.04 0.04
Echinococcus multilocularis fibroblast growth factor receptor 4 0.038 0.091 0.091
Entamoeba histolytica protein kinase, putative 0.0256 0.0462 0.1588
Entamoeba histolytica protein kinase, putative 0.0212 0.03 0.1001
Echinococcus granulosus expressed protein 0.0174 0.0166 0.0166
Loa Loa (eye worm) gastrulation defective protein 1 0.112 0.3585 0.3585
Toxoplasma gondii histone kinase SNF1, putative 0.0164 0.0129 0.0097
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0266 0.0498 0.0498
Plasmodium falciparum glutathione reductase 0.1003 0.3162 0.3139
Echinococcus multilocularis lachesin 0.0306 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0719 0.2134 0.2134
Plasmodium falciparum calcium-dependent protein kinase 1 0.0212 0.03 0.0268
Loa Loa (eye worm) hypothetical protein 0.0253 0.0448 0.0448
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0157 0.0102 0.0102
Echinococcus granulosus tyrosine protein kinase Lyn 0.0389 0.0943 0.0943
Brugia malayi casein kinase 1, delta 0.0228 0.0359 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1381 0.1381
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Entamoeba histolytica casein kinase, putative 0.021 0.0294 0.0981
Plasmodium vivax apical sushi protein, putative 0.054 0.1488 0.1358
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0226 0.0353 0.0353
Brugia malayi cell division control protein 2 homolog 0.0249 0.0436 0.0436
Schistosoma mansoni serine/threonine protein kinase 0.0428 0.1081 0.1081
Onchocerca volvulus 0.0293 0.0593 0.2188
Loa Loa (eye worm) protein kinase domain-containing protein 0.0447 0.115 0.115
Loa Loa (eye worm) hypothetical protein 0.0859 0.264 0.264
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0498 0.1511
Brugia malayi Peroxidasin 0.0306 0.0642 0.0642
Schistosoma mansoni disulfide oxidoreductase 0.0266 0.0498 0.0498
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0212 0.03 0.0268
Trichomonas vaginalis CMGC family protein kinase 0.0291 0.0588 0.1799
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0247 0.0427 0.0427
Entamoeba histolytica protein kinase, putative 0.0151 0.0081 0.0208
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0208 0.0288 0.0288
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0325 0.0709 0.0709
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0266 0.0498 0.0467
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0212 0.03 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0175 0.0175
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0033 0.0032
Schistosoma mansoni protein kinase C mu 0.0456 0.1183 0.1183
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0322 0.0699 0.0669
Giardia lamblia Kinase, CMGC CDK 0.0249 0.0436 0.0901
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0166 0.0134 0.0134
Echinococcus multilocularis protein jagged 1 0.0293 0.0593 0.0593
Onchocerca volvulus 0.0141 0.0044 0.0102
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1971 0.6661 0.6661
Echinococcus multilocularis CDC7 cell division cycle 7 0.0188 0.0216 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.1171 0.1171
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0157 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0234 0.0381 0.0381
Brugia malayi MAP kinase sur-1 0.0176 0.0171 0.0171
Schistosoma mansoni serine/threonine-protein kinase 0.0344 0.0779 0.0779
Trichomonas vaginalis CMGC family protein kinase 0.0176 0.0171 0.0468
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0249 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.038 0.091 0.091
Entamoeba histolytica PH domain containing protein kinase, putative 0.0253 0.0449 0.1543
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0499 0.134 0.4194
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Echinococcus multilocularis hypothetical protein 0.0213 0.0306 0.0306
Giardia lamblia Kinase, CDC7 0.0188 0.0216 0.0168
Echinococcus granulosus protein kinase shaggy 0.027 0.051 0.051
Echinococcus granulosus casein kinase i 0.0228 0.0359 0.0359
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Echinococcus granulosus protein kinase C gamma type 0.0423 0.1064 0.1064
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0452 0.1171 0.1171
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1003 0.3162 0.3139
Schistosoma mansoni peroxidasin 0.0166 0.0136 0.0136
Entamoeba histolytica protein kinase, putative 0.0181 0.0188 0.0595
Echinococcus multilocularis Glutaredoxin protein 5 0.0259 0.0471 0.0471
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0425 0.107 0.107
Loa Loa (eye worm) hypothetical protein 0.0299 0.0616 0.0616
Trichomonas vaginalis CMGC family protein kinase 0.0291 0.0588 0.1799
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0755 0.0755
Mycobacterium tuberculosis Probable oxidoreductase 0.1003 0.3162 0.2803
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Onchocerca volvulus 0.014 0.0042 0.0095
Echinococcus multilocularis PAK box P21 Rho binding 0.0135 0.0024 0.0024
Echinococcus granulosus protein jagged 2 0.0293 0.0593 0.0593
Brugia malayi Muscle positioning protein 4 0.0293 0.0593 0.0593
Echinococcus granulosus raf serine:threonine protein kinase 0.0156 0.0098 0.0098
Echinococcus multilocularis 0.014 0.0042 0.0042
Echinococcus granulosus tyrosine protein kinase Src64B 0.032 0.0692 0.0692
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0553 0.1536 0.1536
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.1536 0.1536
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1003 0.3162 0.7281
Schistosoma mansoni protein kinase 0.0135 0.0024 0.0024
Schistosoma mansoni protein kinase 0.0181 0.0188 0.0188
Brugia malayi protein unc-22 0.0229 0.0362 0.0362
Brugia malayi serine/threonine kinase 12 0.0247 0.0427 0.0427
Brugia malayi map kinase activated protein kinase protein 2 0.0825 0.2518 0.2518
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0306 0.064 0.2369
Loa Loa (eye worm) TK/ROR protein kinase 0.0208 0.0288 0.0288
Echinococcus granulosus cyclin dependent kinase 0.0249 0.0436 0.0436
Entamoeba histolytica serine/threonine protein kinase, putative 0.0164 0.0129 0.0381
Echinococcus granulosus basement membrane specific heparan sulfate 0.0166 0.0134 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.0699 0.0699
Trypanosoma brucei aurora B kinase 0.0247 0.0427 0.0396
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0249 0.0436 0.0404
Brugia malayi Temporarily assigned gene name protein 59 0.0234 0.0381 0.0381
Loa Loa (eye worm) cyclin C 0.177 0.5933 0.5933
Echinococcus multilocularis serine:threonine protein kinase N2 0.0337 0.0755 0.0755
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.014 0.0042 0.0042
Schistosoma mansoni protein kinase 0.0908 0.2819 0.2819
Echinococcus multilocularis tyrosine protein kinase Abl 0.0197 0.0246 0.0246
Echinococcus multilocularis neurogenic locus notch protein 4 0.0293 0.0593 0.0593
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1279 0.4157 0.4157
Loa Loa (eye worm) hypothetical protein 0.0187 0.0211 0.0211
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0266 0.0498 0.0498
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.064 0.064
Giardia lamblia Kinase, CMGC CK2 0.021 0.0294 0.0429
Echinococcus granulosus tyrosine protein kinase Fyn 0.032 0.0692 0.0692
Echinococcus multilocularis casein kinase I alpha 0.0228 0.0359 0.0359
Schistosoma mansoni notch 0.0293 0.0593 0.0593
Schistosoma mansoni vam6/vps39 related 0.0234 0.0381 0.0381
Brugia malayi Protein kinase domain containing protein 0.0137 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0166 0.0134 0.0134
Brugia malayi hypothetical protein 0.0465 0.1218 0.1218
Echinococcus multilocularis tyrosine protein kinase Fyn 0.032 0.0692 0.0692
Echinococcus multilocularis cyclin dependent kinase 19 0.119 0.3836 0.3836
Echinococcus granulosus growth factor receptor bound protein 2 0.0131 0.0008 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0322 0.0699 0.2152
Loa Loa (eye worm) AUR protein kinase 0.0247 0.0427 0.0427
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0291 0.0588 0.0588
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0325 0.0709 0.0709
Loa Loa (eye worm) notch protein 0.0293 0.0593 0.0593
Loa Loa (eye worm) AUR protein kinase 0.0247 0.0427 0.0427
Schistosoma mansoni vesicular amine transporter 0.0553 0.1535 0.1535
Trichomonas vaginalis CAMK family protein kinase 0.0583 0.1643 0.516
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0234 0.0381 0.0349
Schistosoma mansoni kinase 0.0605 0.1721 0.1721
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.1279 0.4157 0.4137
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0266 0.0498 0.1511
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.011 0.011
Echinococcus granulosus lachesin 0.0306 0.064 0.064
Brugia malayi Protein kinase domain containing protein 0.0939 0.2929 0.2929
Onchocerca volvulus 0.029 0.0585 0.2159
Echinococcus granulosus neurogenic locus notch protein 0.0293 0.0593 0.0593
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0436 0.1313
Loa Loa (eye worm) hypothetical protein 0.0572 0.1604 0.1604
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0291 0.0588 0.0588
Schistosoma mansoni titin 0.014 0.0042 0.0042
Plasmodium falciparum ferrodoxin reductase-like protein 0.0266 0.0498 0.0467
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.1279 0.4157 0.4137
Schistosoma mansoni myosin-binding protein-related 0.0159 0.011 0.011
Schistosoma mansoni g1/s-specific cyclin C 0.177 0.5933 0.5933
Trichomonas vaginalis AGC family protein kinase 0.0247 0.0427 0.1285
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0249 0.0436 0.0404
Echinococcus granulosus down syndrome cell adhesion 0.014 0.0042 0.0042
Schistosoma mansoni tyrosine kinase 0.0438 0.1119 0.1119
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0421 0.1055 0.1055
Brugia malayi Protein kinase domain containing protein 0.0406 0.1002 0.1002
Entamoeba histolytica hypothetical protein 0.0256 0.0462 0.1588
Entamoeba histolytica casein kinase 1, putative 0.0228 0.0359 0.1215
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0137 0.0031 0.0031
Trichomonas vaginalis mercuric reductase, putative 0.1003 0.3162 1
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Loa Loa (eye worm) casein kinase 0.0377 0.0899 0.0899
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0266 0.0498 0.0353
Brugia malayi Protein kinase domain containing protein 0.061 0.1738 0.1738
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0174 0.0166 0.0134
Brugia malayi Immunoglobulin I-set domain containing protein 0.144 0.4741 0.4741
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0129 0.0129
Echinococcus multilocularis mitogen activated protein kinase 11 0.0333 0.0741 0.0741
Schistosoma mansoni titin 0.014 0.0042 0.0042
Loa Loa (eye worm) CMGC/GSK protein kinase 0.027 0.051 0.051
Schistosoma mansoni basigin related 0.0166 0.0134 0.0134
Onchocerca volvulus 0.054 0.1488 0.5589
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1035 0.3276 0.3276
Onchocerca volvulus 0.0134 0.002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0213 0.0306 0.0306
Trypanosoma brucei protein kinase, putative 0.0193 0.0232 0.02
Echinococcus multilocularis rac serine:threonine kinase 0.0344 0.0779 0.0779
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0266 0.0498 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Trypanosoma brucei casein kinase I, isoform 2 0.0228 0.0359 0.0327
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0322 0.0699 0.0669
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0513 0.1391 0.1391
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0486 0.1293 0.1293
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Echinococcus granulosus protein kinase c epsilon type 0.0428 0.1081 0.1081
Schistosoma mansoni sulfide quinone reductase 0.0266 0.0498 0.0498
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0216 0.0216
Brugia malayi Protein kinase domain containing protein 0.0188 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.017 0.0152 0.0152
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1003 0.3162 0.3162
Loa Loa (eye worm) animal heme peroxidase 0.014 0.0042 0.0042
Schistosoma mansoni nephrin related 0.014 0.0042 0.0042
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0185 0.0203 0.0203
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Brugia malayi hypothetical protein 0.0137 0.0031 0.0031
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0697 0.2054 0.2054
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.029 0.0582 0.1778
Brugia malayi Protein kinase c protein 2 0.0243 0.0412 0.0412
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0766 0.2302 0.8261
Echinococcus multilocularis casein kinase I alpha 0.0228 0.0359 0.0359
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0141 0.0044 0.0044
Onchocerca volvulus 0.014 0.0042 0.0095
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0134 0.0134
Trichomonas vaginalis glutathione reductase, putative 0.1003 0.3162 1
Brugia malayi intracellular kinase 0.027 0.051 0.051
Brugia malayi Zinc finger, C2H2 type family protein 0.0499 0.134 0.134
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0492 0.1315 0.1315
Brugia malayi EGF-like domain containing protein 0.0293 0.0593 0.0593
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.032 0.0692 0.0692
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0178 0.0178 0.0145
Echinococcus multilocularis neurogenic locus notch protein 0.0293 0.0593 0.0593
Echinococcus multilocularis casein kinase I delta 0.0228 0.0359 0.0359
Echinococcus granulosus cyclin dependent kinase 1 0.0249 0.0436 0.0436
Entamoeba histolytica protein kinase, putative 0.027 0.051 0.1764
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0392 0.1174
Echinococcus multilocularis notch 0.0293 0.0593 0.0593
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0212 0.03 0.03
Echinococcus granulosus dual specificity 0.0291 0.0588 0.0588
Schistosoma mansoni protein kinase 0.0908 0.2819 0.2819
Echinococcus granulosus Immunoglobulin 0.0166 0.0134 0.0134
Schistosoma mansoni glutamate synthase 0.0266 0.0498 0.0498
Brugia malayi Protein kinase domain containing protein 0.0629 0.1808 0.1808
Brugia malayi Protein kinase domain containing protein 0.0337 0.0755 0.0755
Giardia lamblia NADH oxidase lateral transfer candidate 0.1003 0.3162 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0458 0.119 0.119
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0499 0.134 0.4194
Onchocerca volvulus 0.014 0.0042 0.0095
Loa Loa (eye worm) hypothetical protein 0.0299 0.0616 0.0616
Brugia malayi protein kinase C3,putative 0.033 0.073 0.073
Trichomonas vaginalis AGC family protein kinase 0.0359 0.0833 0.2579
Schistosoma mansoni titin 0.0159 0.011 0.011
Brugia malayi Thioredoxin reductase 0.2895 1 1
Plasmodium falciparum tyrosine kinase-like protein, putative 0.017 0.015 0.0118
Echinococcus granulosus nephrin 0.0159 0.011 0.011
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0553 0.1535 0.1535
Entamoeba histolytica protein kinase, putative 0.0174 0.0166 0.0515
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0498 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0493 0.1496
Brugia malayi SH2 domain containing protein 0.0137 0.0031 0.0031
Plasmodium falciparum serine/threonine protein kinase, putative 0.0247 0.0427 0.0396
Trichomonas vaginalis CAMK family protein kinase 0.0265 0.0493 0.1496
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0197 0.0246 0.0246
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0322 0.0699 0.0669
Plasmodium vivax unspecified product 0.021 0.0294 0.0147
Trichomonas vaginalis AGC family protein kinase 0.0247 0.0427 0.1285
Onchocerca volvulus 0.054 0.1488 0.5589
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0166 0.0134 0.0134
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0452 0.1171 0.1171
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0328 0.0722 0.0691
Echinococcus granulosus tyrosine protein kinase shark 0.0363 0.0847 0.0847
Plasmodium vivax serine/threonine protein kinase, putative 0.0174 0.0166 0.0016
Echinococcus multilocularis mitogen activated protein kinase 14 0.0333 0.0741 0.0741
Loa Loa (eye worm) AGC/NDR protein kinase 0.0337 0.0755 0.0755
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0825 0.2518 0.2518
Echinococcus granulosus fibropellin Ia 0.0293 0.0593 0.0593
Toxoplasma gondii AGC kinase 0.0237 0.0392 0.0361
Echinococcus granulosus tyrosine protein kinase Fyn 0.032 0.0692 0.0692
Entamoeba histolytica protein kinase domain containing protein 0.027 0.051 0.1764
Schistosoma mansoni slit 0.0293 0.0595 0.0595
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0237 0.0392 0.0361
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0157 0.0102 0.0102
Schistosoma mansoni hemicentin 0.0159 0.011 0.011
Giardia lamblia Kinase, AGC PKA 0.0237 0.0392 0.0755
Leishmania major casein kinase II, putative 0.021 0.0294 0.0263
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Trichomonas vaginalis AGC family protein kinase 0.0247 0.0427 0.1285
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0212 0.03 0.03
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0266 0.0497 0.0497
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.1279 0.4157 1
Schistosoma mansoni serine/threonine-protein kinase 0.0344 0.0779 0.0779
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0164 0.0129 0.0097
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0343 0.0776 0.0776
Loa Loa (eye worm) TK/INSR protein kinase 0.0629 0.1808 0.1808
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0164 0.0129 0.0097
Echinococcus multilocularis mitogen activated protein kinase 3 0.0176 0.0171 0.0171
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0719 0.2134 0.2134
Trypanosoma cruzi cdc2-related kinase 1 0.0249 0.0436 0.0404
Echinococcus granulosus Immunoglobulin 0.0166 0.0134 0.0134
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0328 0.0722 0.0691
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0159 0.011 0.011
Plasmodium falciparum NIMA related kinase 1 0.0285 0.0567 0.0536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0203 0.0203
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0228 0.0359 0.0359
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0178 0.0178 0.0145
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0452 0.1171 0.1171
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0362 0.0362
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0266 0.0498 0.0467
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0266 0.0498 0.0498
Entamoeba histolytica hypothetical protein 0.0402 0.0988 0.3494
Echinococcus multilocularis dual specificity protein kinase clk2 0.0322 0.0699 0.0699
Entamoeba histolytica p21-activated kinase 0.0196 0.0245 0.0802
Schistosoma mansoni neuroglian 0.0325 0.0709 0.0709
Giardia lamblia Kinase, CAMK CAMKL 0.0181 0.0191 0.0082
Echinococcus granulosus cGMP dependent protein kinase 0.0177 0.0175 0.0175
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.014 0.0042 0.0042
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.1279 0.4157 0.4137
Plasmodium falciparum apical sushi protein 0.054 0.1488 0.146
Brugia malayi STE20-like kinase MST 0.0538 0.148 0.148
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0208 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Echinococcus multilocularis 0.0321 0.0695 0.0695
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0247 0.0427 0.0281
Brugia malayi Immunoglobulin I-set domain containing protein 0.0229 0.0362 0.0362
Brugia malayi Protein kinase domain containing protein 0.0669 0.1953 0.1953
Echinococcus granulosus thioredoxin glutathione reductase 0.2895 1 1
Loa Loa (eye worm) hypothetical protein 0.0553 0.1535 0.1535
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Echinococcus granulosus tyrosine protein kinase 0.0322 0.0698 0.0698
Echinococcus multilocularis dual specificity 0.0256 0.0462 0.0462
Schistosoma mansoni cell adhesion molecule 0.0738 0.2202 0.2202
Echinococcus multilocularis casein kinase I delta 0.0228 0.0359 0.0359
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0212 0.03 0.0152
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0368 0.0867 0.0867
Brugia malayi serine/threonine-protein kinase 6 0.0247 0.0427 0.0427
Leishmania major hypothetical protein, conserved 0.0266 0.0498 0.0467
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0181 0.0188 0.0188
Brugia malayi Immunoglobulin domain containing protein 0.0166 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0485 0.1289 0.1289
Loa Loa (eye worm) CMGC/GSK protein kinase 0.027 0.051 0.051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Echinococcus granulosus casein kinase I alpha 0.0228 0.0359 0.0359
Echinococcus multilocularis expressed protein 0.0174 0.0166 0.0166
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0768 0.2311 0.2311
Echinococcus multilocularis NCK adaptor protein 0.0131 0.0008 0.0008
Echinococcus granulosus protein kinase 0.0321 0.0695 0.0695
Schistosoma mansoni serine/threonine protein kinase 0.119 0.3836 0.3836
Brugia malayi Animal haem peroxidase family protein 0.014 0.0042 0.0042
Onchocerca volvulus 0.0402 0.0989 0.3694
Echinococcus granulosus protein kinase c iota type 0.0598 0.1698 0.1698
Echinococcus multilocularis glutamate synthase 0.0266 0.0498 0.0498
Loa Loa (eye worm) hypothetical protein 0.0187 0.0211 0.0211
Echinococcus granulosus neural cadherin 0.0293 0.0593 0.0593
Schistosoma mansoni titin 0.014 0.0042 0.0042
Brugia malayi Fibronectin type III domain containing protein 0.0572 0.1604 0.1604
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0229 0.0362 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0166 0.0166
Brugia malayi hypothetical protein 0.0572 0.1604 0.1604
Schistosoma mansoni tyrosine kinase 0.0506 0.1365 0.1365
Loa Loa (eye worm) thyroid receptor interactor 0.0214 0.0309 0.0309
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0266 0.0498 0.0498
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1003 0.3162 0.7281
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1581 0.4963
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0333 0.0741 0.071
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0234 0.0381 0.0381
Schistosoma mansoni serine/threonine protein kinase 0.0566 0.1581 0.1581
Echinococcus granulosus casein kinase I delta 0.0228 0.0359 0.0359
Entamoeba histolytica protein kinase, putative 0.0171 0.0154 0.047
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1381 0.1381
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0266 0.0498 0.0498
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0168 0.0141 0.0141
Schistosoma mansoni ste20-related kinase 0.043 0.1089 0.1089
Echinococcus multilocularis myosin iiia 0.0178 0.0178 0.0178
Echinococcus multilocularis neuroglian 0.0325 0.0709 0.0709
Schistosoma mansoni septate junction protein 0.0306 0.064 0.064
Schistosoma mansoni notch 0.0293 0.0593 0.0593
Loa Loa (eye worm) TK/KIN16 protein kinase 0.144 0.4741 0.4741
Onchocerca volvulus 0.054 0.1488 0.5589
Loa Loa (eye worm) TK/FAK protein kinase 0.061 0.1738 0.1738
Brugia malayi serine/threonine-protein kinase PAK 7 0.0486 0.1293 0.1293
Brugia malayi Protein kinase domain containing protein 0.0174 0.0166 0.0166
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1279 0.4157 0.4157
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Echinococcus granulosus slit 2 protein 0.0339 0.0761 0.0761
Echinococcus multilocularis N chimaerin 0.0157 0.0102 0.0102
Echinococcus granulosus hemicentin 1 0.0306 0.064 0.064
Brugia malayi probable protein kinase 0.0555 0.1541 0.1541
Echinococcus granulosus serine/threonine protein kinase 0.0344 0.0779 0.0779
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0266 0.0498 0.0498
Brugia malayi Protein kinase domain containing protein 0.0171 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0166 0.0134 0.0134
Onchocerca volvulus Tyrosine kinase homolog 0.0862 0.2649 1
Toxoplasma gondii AGC kinase 0.0237 0.0392 0.0361
Echinococcus multilocularis cyclin dependent kinase 5 0.0249 0.0436 0.0436
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0669 0.1953 0.1953
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0171 0.0154 0.0154
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0176 0.0171 0.0138
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0766 0.2302 0.2302
Entamoeba histolytica protein kinase domain containing protein 0.0291 0.0588 0.2047
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0566 0.1581 0.1581
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0304 0.0633 0.0633
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0465 0.1218 0.1218
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0266 0.0498 0.0467
Echinococcus granulosus casein kinase I alpha 0.0228 0.0359 0.0359
Giardia lamblia Kinase, CMGC GSK 0.027 0.051 0.115
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0648 0.1877 0.1877
Echinococcus granulosus tyrosine protein kinase Src42A 0.0195 0.0239 0.0239
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0886 0.2736 0.2736
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0166 0.0134 0.0134
Brugia malayi Protein kinase domain containing protein 0.0137 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0294 0.0599 0.0599
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0766 0.2302 0.2302
Trypanosoma brucei protein kinase, putative 0.027 0.051 0.0479
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1003 0.3162 0.3139
Brugia malayi Protein kinase domain containing protein 0.013 0.0005 0.0005
Trichomonas vaginalis CK1 family protein kinase 0.0228 0.0359 0.1068
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.038 0.091 0.091
Leishmania major protein kinase, putative 0.0212 0.03 0.0268
Echinococcus multilocularis serine:threonine protein kinase N2 0.0609 0.1735 0.1735
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0344 0.0779 0.0749
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0513 0.1391 0.1391
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0266 0.0498 0.0498
Onchocerca volvulus 0.027 0.051 0.1876
Schistosoma mansoni septate junction protein 0.0166 0.0134 0.0134
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0485 0.1289 0.1289
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0129 0.0129
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0266 0.0498 0.0498
Schistosoma mansoni titin 0.0229 0.0362 0.0362
Trypanosoma cruzi polo-like protein kinase, putative 0.0566 0.1581 0.1554
Loa Loa (eye worm) cyclin domain-containing protein 0.0886 0.2736 0.2736
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0178 0.0178 0.0557
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Brugia malayi basement membrane proteoglycan 0.0166 0.0134 0.0134
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0187 0.021 0.021
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0237 0.0392 0.0361
Giardia lamblia Kinase, CMGC DYRK 0.0291 0.0588 0.141
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Brugia malayi p70 ribosomal S6 kinase beta 0.0596 0.169 0.169
Loa Loa (eye worm) TK protein kinase 0.052 0.1416 0.1416
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0237 0.0392 0.0361
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Brugia malayi EGF-like domain containing protein 0.0293 0.0593 0.0593
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.1279 0.4157 0.4137
Trichomonas vaginalis CK1 family protein kinase 0.0228 0.0359 0.1068
Loa Loa (eye worm) TK/ALK protein kinase 0.0318 0.0685 0.0685
Echinococcus granulosus casein kinase ii subunit alpha 0.021 0.0294 0.0294
Trichomonas vaginalis CAMK family protein kinase 0.0241 0.0408 0.1223
Echinococcus multilocularis tyrosine protein kinase Fyn 0.032 0.0692 0.0692
Echinococcus multilocularis roundabout 2 0.0325 0.0709 0.0709
Onchocerca volvulus 0.0293 0.0593 0.2188
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Schistosoma mansoni growth factor receptor-bound protein 0.0131 0.0008 0.0008
Brugia malayi Protein kinase domain 0.0181 0.0188 0.0188
Echinococcus granulosus tyrosine protein kinase Src42A 0.032 0.0692 0.0692
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0738 0.2204 0.8308
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Onchocerca volvulus 0.0266 0.0498 0.1828
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Entamoeba histolytica protein kinase, putative 0.0596 0.169 0.6041
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Trypanosoma brucei trypanothione reductase 0.2895 1 1
Schistosoma mansoni protein kinase 0.0463 0.1209 0.1209
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0463 0.1209 0.1209
Echinococcus granulosus Immunoglobulin 0.0553 0.1535 0.1535
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Trichomonas vaginalis AGC family protein kinase 0.0247 0.0427 0.1285
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1003 0.3162 0.3162
Echinococcus granulosus tyrosine protein kinase ABL1 0.0137 0.0031 0.0031
Brugia malayi Variant SH3 domain containing protein 0.0157 0.0102 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0239 0.04 0.12
Schistosoma mansoni hypothetical protein 0.0213 0.0306 0.0306
Brugia malayi Immunoglobulin I-set domain containing protein 0.0226 0.0353 0.0353
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0176 0.0171 0.0138
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0261 0.0477 0.0477
Plasmodium vivax casein kinase 1, putative 0.0228 0.0359 0.0212
Schistosoma mansoni cell adhesion molecule 0.0166 0.0134 0.0134
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0234 0.0381 0.0349
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0154 0.0413
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0138 0.0138
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0291 0.0588 0.0558
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0266 0.0498 0.0498
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0098 0.0098
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0266 0.0498 0.0467
Echinococcus multilocularis casein kinase ii subunit alpha 0.021 0.0294 0.0294
Entamoeba histolytica protein kinase domain containing protein 0.0256 0.0462 0.1588
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0266 0.0498 0.0467
Echinococcus granulosus neurogenic locus notch protein 0.0293 0.0593 0.0593
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.064 0.064
Schistosoma mansoni sulfide quinone reductase 0.0266 0.0498 0.0498
Loa Loa (eye worm) hypothetical protein 0.0601 0.1707 0.1707
Trypanosoma cruzi Protein kinase B 0.0344 0.0779 0.0749
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0939 0.2929 0.2929
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.119 0.119
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0178 0.0178 0.0557
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0825 0.2518 0.2518
Echinococcus granulosus cyclin dependent kinase 9 0.0184 0.0199 0.0199
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0228 0.0359 0.0359
Trichomonas vaginalis CMGC family protein kinase 0.0291 0.0588 0.1799
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Brugia malayi RhoGAP domain containing protein 0.0157 0.0102 0.0102
Trichomonas vaginalis CMGC family protein kinase 0.0291 0.0588 0.1799
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.1279 0.4157 0.385
Loa Loa (eye worm) hypothetical protein 0.0306 0.064 0.064
Trichomonas vaginalis AGC family protein kinase 0.0285 0.0567 0.1731
Loa Loa (eye worm) hypothetical protein 0.0628 0.1804 0.1804
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1315 0.1315
Schistosoma mansoni nephrin 0.0325 0.0709 0.0709
Trypanosoma cruzi hypothetical protein, conserved 0.0266 0.0498 0.0467
Plasmodium falciparum calcium-dependent protein kinase 5 0.0212 0.03 0.0268
Echinococcus multilocularis epidermal growth factor receptor 0.0506 0.1365 0.1365
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Plasmodium falciparum casein kinase 2, alpha subunit 0.021 0.0294 0.0263
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1526 0.5051 0.5051
Trypanosoma cruzi casein kinase II, putative 0.021 0.0294 0.0263
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0455 0.1178 0.1178
Brugia malayi Immunoglobulin I-set domain containing protein 0.0325 0.0709 0.0709
Loa Loa (eye worm) thioredoxin reductase 0.2895 1 1
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0339 0.0761 0.0761
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.014 0.0042 0.0042
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0212 0.03 0.03
Echinococcus multilocularis protein jagged 1 0.0293 0.0593 0.0593
Echinococcus granulosus cGMP dependent protein kinase 1 0.0177 0.0175 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1581 0.4963
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0436 0.1313
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0212 0.03 0.03
Echinococcus multilocularis protein kinase shaggy 0.027 0.051 0.051
Brugia malayi Protein kinase domain containing protein 0.0612 0.1747 0.1747
Brugia malayi casein kinase I 0.0228 0.0359 0.0359
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0177 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0572 0.1604 0.1604
Echinococcus granulosus glycogen synthase kinase 3 beta 0.027 0.051 0.051
Brugia malayi glutamate synthase 0.0266 0.0498 0.0498
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0291 0.0588 0.0558
Giardia lamblia Kinase, CMGC MAPK 0.0176 0.0171 0.0016
Brugia malayi Kinase associated domain 1 family protein 0.0213 0.0306 0.0306
Brugia malayi Protein kinase domain containing protein 0.0768 0.2311 0.2311
Loa Loa (eye worm) hypothetical protein 0.0306 0.064 0.064
Giardia lamblia Kinase, CMGC CLK 0.0322 0.0699 0.1781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0176 0.0171 0.0138
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0261 0.0477 0.0477
Echinococcus multilocularis Immunoglobulin subtype 0.0166 0.0134 0.0134
Echinococcus granulosus glutamate synthase 0.0266 0.0498 0.0498
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0553 0.1535 0.1535
Echinococcus multilocularis expressed conserved protein 0.0177 0.0175 0.0175
Brugia malayi serine/threonine protein kinase 6 0.0247 0.0427 0.0427
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0344 0.0778 0.0778
Entamoeba histolytica protein kinase, putative 0.0247 0.0427 0.1462
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0249 0.0436 0.0404
Entamoeba histolytica PH domain containing protein kinase, putative 0.0253 0.0449 0.1543
Schistosoma mansoni hypothetical protein 0.014 0.0042 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0241 0.0408 0.1223
Echinococcus granulosus defective proboscis extension response 0.0553 0.1535 0.1535
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0159 0.011 0.011
Schistosoma mansoni protein kinase 0.0228 0.0359 0.0359
Echinococcus granulosus neurogenic locus protein delta 0.0293 0.0593 0.0593
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0697 0.2054 0.2054
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Brugia malayi EGF-like domain containing protein 0.0293 0.0593 0.0593
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Loa Loa (eye worm) TK/EPH protein kinase 0.0239 0.0398 0.0398
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.014 0.0042 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1581 0.4963
Schistosoma mansoni serine/threonine protein kinase 0.0999 0.3144 0.3144
Loa Loa (eye worm) hypothetical protein 0.0325 0.0709 0.0709
Brugia malayi Myb-like DNA-binding domain containing protein 0.014 0.0042 0.0042
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0266 0.0498 0.1511
Brugia malayi Tyrosine-protein kinase abl-1 0.0197 0.0246 0.0246
Schistosoma mansoni protein kinase 0.0247 0.0427 0.0427
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0181 0.0191 0.0041
Entamoeba histolytica protein kinase, putative 0.0139 0.0036 0.0046
Brugia malayi C1-like domain containing protein 0.0456 0.1183 0.1183
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0176 0.0171 0.0138
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Schistosoma mansoni tyrosine kinase 0.0603 0.1715 0.1715
Echinococcus multilocularis c src tyrosine kinase 0.0197 0.0246 0.0246
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0498 0.1511
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0212 0.03 0.0268
Echinococcus multilocularis serine:threonine protein kinase 3 0.0538 0.148 0.148
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0266 0.0497 0.0497
Schistosoma mansoni tyrosine kinase 0.0438 0.1119 0.1119
Giardia lamblia Kinase, CMGC CDK 0.0249 0.0436 0.0901
Schistosoma mansoni serine/threonine protein kinase 0.0738 0.2204 0.2204
Trypanosoma brucei NADH dehydrogenase 0.0266 0.0498 0.0467
Echinococcus multilocularis mitogen activated protein kinase 11 0.0333 0.0741 0.0741
Echinococcus multilocularis protein kinase c iota type 0.0598 0.1698 0.1698
Entamoeba histolytica cell division protein kinase 2, putative 0.0249 0.0436 0.1494
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.064 0.064
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0261 0.048 0.0449
Schistosoma mansoni protein kinase 0.0555 0.1541 0.1541
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0553 0.1535 0.1535
Loa Loa (eye worm) hypothetical protein 0.0164 0.0129 0.0129
Plasmodium falciparum calcium-dependent protein kinase 2 0.0212 0.03 0.0268
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.027 0.051 0.0479
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0154 0.0154
Onchocerca volvulus Peroxidasin homolog 0.0141 0.0044 0.0102
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0378 0.0901 0.0901
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Echinococcus granulosus pro neuregulin 2 membrane bound 0.014 0.0042 0.0042
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.027 0.051 0.051
Echinococcus granulosus tyrosine kinase 0.0137 0.0031 0.0031
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.014 0.0042 0.0042
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0166 0.0134 0.0134
Brugia malayi Protein kinase domain containing protein 0.0344 0.0778 0.0778
Echinococcus granulosus insulin growth factor binding 0.014 0.0042 0.0042
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0344 0.0778 0.0778
Loa Loa (eye worm) hypothetical protein 0.0166 0.0134 0.0134
Echinococcus multilocularis nervana 2 0.0259 0.0471 0.0471
Toxoplasma gondii AGC kinase 0.0596 0.169 0.1663
Onchocerca volvulus Serine\/threonine kinase homolog 0.0566 0.1581 0.5944
Brugia malayi Cadherin domain containing protein 0.0293 0.0593 0.0593
Schistosoma mansoni glutamate synthase 0.0266 0.0498 0.0498
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1003 0.3162 0.2803
Brugia malayi cyclin-dependent kinase 9 0.0167 0.0138 0.0138
Schistosoma mansoni serine/threonine kinase 0.0337 0.0755 0.0755
Schistosoma mansoni serine/threonine protein kinase 0.0447 0.115 0.115
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Brugia malayi Fes/CIP4 homology domain containing protein 0.0214 0.0309 0.0309
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0237 0.0392 0.0361
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Onchocerca volvulus 0.014 0.0042 0.0095
Echinococcus granulosus tyrosine kinase 0.0261 0.0477 0.0477
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0333 0.0741 0.071
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0428 0.1081 0.1081
Trichomonas vaginalis AGC family protein kinase 0.0612 0.1747 0.5493
Onchocerca volvulus 0.054 0.1488 0.5589
Echinococcus granulosus epidermal growth factor receptor 0.0726 0.2161 0.2161
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0392 0.0392
Schistosoma mansoni cell polarity protein 0.0293 0.0593 0.0593
Schistosoma mansoni hypothetical protein 0.014 0.0042 0.0042
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1003 0.3162 0.3139
Brugia malayi Protein kinase domain containing protein 0.0669 0.1953 0.1953
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0456 0.1183 0.1183
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0498 0.0467
Echinococcus multilocularis serine:threonine protein kinase 38 0.0337 0.0755 0.0755
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1003 0.3162 0.7281
Echinococcus multilocularis cyclin dependent kinase 9 0.0184 0.0199 0.0199
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0249 0.0436 0.0436
Brugia malayi Calcium binding EGF domain containing protein 0.0293 0.0593 0.0593
Leishmania major protein kinase A catalytic subunit 0.0237 0.0392 0.0361
Echinococcus multilocularis nervana 2 0.0259 0.0471 0.0471
Schistosoma mansoni protein kinase 0.0908 0.2819 0.2819
Brugia malayi Protein kinase domain containing protein 0.0256 0.0462 0.0462
Echinococcus multilocularis neurogenic locus protein delta 0.0293 0.0593 0.0593
Schistosoma mansoni titin 0.014 0.0042 0.0042
Trypanosoma brucei SNF1-related protein kinases, putative 0.0164 0.0129 0.0097
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0425 0.107 0.107
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0738 0.2204 0.2204
Entamoeba histolytica protein kinase domain containing protein 0.0425 0.107 0.3792
Entamoeba histolytica protein kinase domain containing protein 0.027 0.051 0.1764
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0738 0.2204 0.2204
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0306 0.064 0.064
Schistosoma mansoni notch 0.0293 0.0593 0.0593
Brugia malayi SRC-1 0.032 0.0692 0.0692
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Schistosoma mansoni atypical protein kinase C 0.0611 0.1744 0.1744
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0212 0.03 0.03
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0566 0.1581 0.1581
Entamoeba histolytica protein kinase, putative 0.0151 0.0081 0.0208
Echinococcus multilocularis cyclin dependent kinase 0.0249 0.0436 0.0436
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1003 0.3162 0.3058
Schistosoma mansoni protein kinase 0.021 0.0294 0.0294
Brugia malayi Protein kinase domain containing protein 0.0421 0.1056 0.1056
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0386 0.0932 0.0932
Onchocerca volvulus 0.0611 0.1745 0.6565
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1003 0.3162 0.7281
Toxoplasma gondii casein kinase I 0.0228 0.0359 0.0327
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1003 0.3162 0.3139
Schistosoma mansoni hypothetical protein 0.0159 0.011 0.011
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0293 0.0593 0.0593
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.011 0.011
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.014 0.0042 0.0042
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1003 0.3162 0.3162
Brugia malayi Immunoglobulin domain containing protein 0.0166 0.0134 0.0134
Brugia malayi hypothetical protein 0.054 0.1488 0.1488
Onchocerca volvulus 0.0137 0.0031 0.0055
Echinococcus multilocularis tyrosine protein kinase Fgr 0.032 0.0692 0.0692
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0359 0.0833 0.0833
Echinococcus multilocularis tyrosine kinase 0.0137 0.0031 0.0031
Giardia lamblia Kinase, PLK 0.0566 0.1581 0.4725
Echinococcus multilocularis tyrosine protein kinase 0.0322 0.0698 0.0698
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0333 0.0741 0.071
Onchocerca volvulus 0.0188 0.0216 0.0758
Entamoeba histolytica thioredoxin reductase, putative 0.0266 0.0498 0.1719
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1003 0.3162 0.3139
Loa Loa (eye worm) TK/EGFR protein kinase 0.0726 0.2161 0.2161
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0171 0.0154 0.0154
Trypanosoma cruzi trypanothione reductase, putative 0.1003 0.3162 0.3139
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0285 0.0567 0.0423
Echinococcus granulosus neurogenic locus notch protein 4 0.0293 0.0593 0.0593
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0266 0.0498 0.1109
Echinococcus multilocularis hemicentin 1 0.0306 0.064 0.064
Schistosoma mansoni hypothetical protein 0.0213 0.0306 0.0306
Trichomonas vaginalis CMGC family protein kinase 0.0176 0.0171 0.0468
Plasmodium falciparum thioredoxin reductase 0.1003 0.3162 0.3139
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0171 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.039 0.0944 0.0944
Loa Loa (eye worm) hypothetical protein 0.0237 0.0392 0.0392
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Schistosoma mansoni tyrosine kinase 0.0506 0.1365 0.1365
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0337 0.0755 0.0755
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.032 0.0692 0.0692
Echinococcus granulosus cyclin dependent kinase 9 0.0167 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0306 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.014 0.0042 0.0042
Brugia malayi phosphoinositide-dependent protein kinase I 0.0171 0.0154 0.0154
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0333 0.0741 0.071
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.0427 0.1462
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0463 0.1209 0.1209
Trichomonas vaginalis CAMK family protein kinase 0.0164 0.0129 0.0335
Leishmania major hypothetical protein, conserved 0.0266 0.0498 0.0467
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0212 0.03 0.0152
Brugia malayi Prion-like- 0.0306 0.064 0.064
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Loa Loa (eye worm) hypothetical protein 0.0306 0.064 0.064
Echinococcus multilocularis tyrosine protein kinase Fyn 0.032 0.0692 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0421 0.1056 0.1056
Echinococcus granulosus protein jagged 2 0.0293 0.0593 0.0593
Onchocerca volvulus 0.054 0.1488 0.5589
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0768 0.2311 0.2311
Toxoplasma gondii aurora kinase 0.0247 0.0427 0.0396
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.1279 0.4157 0.4137
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0425 0.107 0.107
Schistosoma mansoni protein kinase 0.0404 0.0995 0.0995
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0499 0.134 0.4194
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Schistosoma mansoni hypothetical protein 0.0166 0.0134 0.0134
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0266 0.0498 0.1719
Loa Loa (eye worm) CDC7 protein kinase 0.0188 0.0216 0.0216
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0174 0.0166 0.0134
Loa Loa (eye worm) hypothetical protein 0.0859 0.264 0.264
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0256 0.0462 0.0431
Echinococcus multilocularis dual specificity 0.0291 0.0588 0.0588
Schistosoma mansoni netrin receptor unc5 0.0166 0.0134 0.0134
Echinococcus granulosus CDC7 cell division cycle 7 0.0188 0.0216 0.0216
Schistosoma mansoni protein kinase 0.0463 0.1209 0.1209
Trypanosoma cruzi casein kinase, putative 0.0228 0.0359 0.0327
Loa Loa (eye worm) disorganized muscle protein 1 0.014 0.0042 0.0042
Trichomonas vaginalis CK1 family protein kinase 0.0228 0.0359 0.1068
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.064 0.064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.064 0.064
Plasmodium vivax thioredoxin reductase, putative 0.2895 1 1
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1003 0.3162 0.2803
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1003 0.3162 1
Trichomonas vaginalis CMGC family protein kinase 0.0291 0.0588 0.1799
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0259 0.0471 0.0471
Brugia malayi hypothetical protein 0.0234 0.0381 0.0381
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0404 0.0995 0.0995
Giardia lamblia Thioredoxin reductase 0.0266 0.0498 0.1109
Brugia malayi Protein kinase domain containing protein 0.0137 0.0031 0.0031
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0237 0.0392 0.0361
Entamoeba histolytica protein kinase, putative 0.0214 0.031 0.1036
Schistosoma mansoni cell adhesion molecule 0.0306 0.064 0.064
Schistosoma mansoni tyrosine kinase 0.0438 0.1119 0.1119
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0136 0.0136
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0164 0.0129 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0436 0.0436
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0328 0.0722 0.0722
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0266 0.0498 0.0467
Echinococcus multilocularis neurogenic locus protein delta 0.0293 0.0593 0.0593
Onchocerca volvulus Putative cubilin 0.0293 0.0593 0.2188
Echinococcus multilocularis tyrosine protein kinase shark 0.0363 0.0847 0.0847
Giardia lamblia Kinase, NEK 0.0285 0.0567 0.1339
Echinococcus granulosus protein jagged 1 0.0293 0.0593 0.0593
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Onchocerca volvulus 0.054 0.1488 0.5589
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.027 0.051 0.051
Leishmania major protein kinase, putative 0.0322 0.0699 0.0669
Onchocerca volvulus 0.0386 0.0932 0.3477
Entamoeba histolytica protein kinase, putative 0.0247 0.0427 0.1462
Echinococcus multilocularis neurogenic locus notch protein 0.0293 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0511 0.1381 0.1381
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0498 0.1511
Loa Loa (eye worm) hypothetical protein 0.0402 0.0989 0.0989
Onchocerca volvulus 0.0159 0.011 0.0356
Echinococcus multilocularis serine threonine protein kinase 0.0423 0.1064 0.1064
Plasmodium falciparum thioredoxin reductase 0.2895 1 1
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0237 0.0392 0.0246
Brugia malayi Protein kinase domain containing protein 0.0322 0.0698 0.0698
Trypanosoma brucei hypothetical protein, conserved 0.0266 0.0498 0.0467
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0178 0.0178 0.0145
Schistosoma mansoni notch 0.0293 0.0593 0.0593
Echinococcus granulosus Glutaredoxin protein 5 0.0259 0.0471 0.0471
Schistosoma mansoni cell adhesion molecule 0.0159 0.011 0.011
Toxoplasma gondii NADPH-glutathione reductase 0.1003 0.3162 0.3139
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0738 0.2204 0.2204
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0212 0.03 0.0268
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0344 0.0778 0.0778
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0234 0.0381 0.0349
Echinococcus granulosus tyrosine protein kinase HCK 0.0191 0.0227 0.0227
Entamoeba histolytica protein kinase, putative 0.0337 0.0755 0.2651
Echinococcus granulosus contactin 0.0325 0.0709 0.0709
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0497 0.0497
Onchocerca volvulus 0.0229 0.0362 0.131
Trypanosoma cruzi polo-like protein kinase, putative 0.0566 0.1581 0.1554
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1003 0.3162 0.3058
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.032 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.0134 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Echinococcus multilocularis titin 0.0229 0.0362 0.0362
Echinococcus granulosus nervana 2 0.0259 0.0471 0.0471
Loa Loa (eye worm) hypothetical protein 0.0234 0.0381 0.0381
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0498 0.1511
Trichomonas vaginalis AGC family protein kinase 0.0375 0.089 0.2762
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0499 0.134 0.4194
Echinococcus granulosus cyclin dependent kinase 5 0.0249 0.0436 0.0436
Schistosoma mansoni serine/threonine protein kinase 0.0465 0.1218 0.1218
Loa Loa (eye worm) hypothetical protein 0.0306 0.064 0.064
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0166 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.0293 0.0593 0.0593
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0648 0.1877 0.1877
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0249 0.0436 0.0436
Echinococcus granulosus hypothetical protein 0.0253 0.0448 0.0448
Plasmodium vivax calcium-dependent protein kinase, putative 0.0212 0.03 0.0152
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0158 0.0108 0.0076
Onchocerca volvulus 0.054 0.1488 0.5589
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0237 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.0166 0.0134 0.0134
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0188 0.0215 0.0215
Echinococcus granulosus serine:threonine protein kinase N2 0.0609 0.1735 0.1735
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0159 0.011 0.011
Echinococcus multilocularis fat cadherin tumor suppressor 0.0293 0.0593 0.0593
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0166 0.0134 0.0134
Brugia malayi Protein kinase domain containing protein 0.0239 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Brugia malayi Immunoglobulin I-set domain containing protein 0.052 0.1416 0.1416
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0212 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.0699 0.0699
Brugia malayi pregnancy-associated plasma protein-A 0.054 0.1488 0.1488
Echinococcus multilocularis serine:threonine protein kinase 0.0239 0.04 0.04
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0216 0.0613
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0294 0.0862
Schistosoma mansoni hypothetical protein 0.0166 0.0134 0.0134
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0176 0.0171 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0392 0.0392
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0291 0.0588 0.0558
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0177 0.0175 0.0143
Giardia lamblia Kinase, CK1 Casein kinase 0.0228 0.0359 0.0645
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0766 0.2302 0.7262
Loa Loa (eye worm) AUR protein kinase 0.0247 0.0427 0.0427
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0266 0.0498 0.0498
Trypanosoma brucei cdc2-related kinase 1 0.0249 0.0436 0.0404
Loa Loa (eye worm) hypothetical protein 0.0166 0.0134 0.0134
Leishmania major casein kinase, putative 0.0228 0.0359 0.0327
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0266 0.0498 0.1719
Brugia malayi EGF-like domain containing protein 0.0293 0.0593 0.0593
Trypanosoma brucei polo-like protein kinase 0.0566 0.1581 0.1554
Brugia malayi Protein kinase domain containing protein 0.0137 0.0031 0.0031
Onchocerca volvulus 0.0188 0.0216 0.0758
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.021 0.021
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0333 0.0741 0.0741
Loa Loa (eye worm) hypothetical protein 0.0137 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.018 0.0185 0.0185
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0256 0.0462 0.0462
Brugia malayi Immunoglobulin I-set domain containing protein 0.0325 0.0709 0.0709
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.1279 0.4157 0.4068
Echinococcus multilocularis insulin receptor 0.0629 0.1808 0.1808
Trichomonas vaginalis CMGC family protein kinase 0.0188 0.0216 0.0613
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1003 0.3162 0.3139
Plasmodium falciparum cGMP-dependent protein kinase 0.0177 0.0175 0.0143
Brugia malayi Immunoglobulin I-set domain containing protein 0.014 0.0042 0.0042
Echinococcus multilocularis protein tyrosine kinase 0.0603 0.1715 0.1715
Loa Loa (eye worm) hypothetical protein 0.0669 0.1953 0.1953
Leishmania major hypothetical protein, conserved 0.0266 0.0498 0.0467
Loa Loa (eye worm) TK protein kinase 0.0389 0.0941 0.0941
Echinococcus granulosus ephrin type A receptor 4 A 0.0202 0.0266 0.0266
Onchocerca volvulus Peroxidasin homolog 0.014 0.0042 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0392 0.0392
Loa Loa (eye worm) hypothetical protein 0.054 0.1488 0.1488
Loa Loa (eye worm) hypothetical protein 0.0293 0.0593 0.0593
Entamoeba histolytica casein kinase, putative 0.0228 0.0359 0.1215
Schistosoma mansoni protein kinase 0.0138 0.0033 0.0033
Echinococcus multilocularis cyclin dependent kinase 9 0.0167 0.0138 0.0138
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1003 0.3162 0.3139
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1003 0.3162 0.3139
Echinococcus granulosus activin receptor type 0.0138 0.0033 0.0033
Onchocerca volvulus 0.0653 0.1897 0.7143
Schistosoma mansoni serine/threonine protein kinase 0.0609 0.1735 0.1735
Giardia lamblia Kinase, CAMK CAMKL 0.0181 0.0191 0.0082
Schistosoma mansoni c4b-binding protein beta chain 0.054 0.1488 0.1488
Echinococcus multilocularis Immunoglobulin 0.0553 0.1535 0.1535
Entamoeba histolytica protein kinase 2, putative 0.0328 0.0722 0.2531
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0256 0.0462 0.0431
Brugia malayi ephrin receptor 1 precursor 0.0131 0.001 0.001
Loa Loa (eye worm) one IG domain family member 0.014 0.0042 0.0042
Onchocerca volvulus 0.054 0.1488 0.5589
Echinococcus granulosus titin 0.014 0.0042 0.0042
Trichomonas vaginalis STE family protein kinase 0.0181 0.0188 0.0523
Plasmodium falciparum protein serine/threonine kinase-1 0.0322 0.0699 0.0669
Brugia malayi Stress-activated protein kinase jnk-1 0.0553 0.1536 0.1536
Leishmania major protein kinase, putative 0.0322 0.0699 0.0669
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.1279 0.4157 1
Leishmania major protein kinase A catalytic subunit isoform 1 0.0237 0.0392 0.0361
Brugia malayi Immunoglobulin I-set domain containing protein 0.0572 0.1604 0.1604
Echinococcus granulosus notch 0.0293 0.0593 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0825 0.2518 0.2518
Echinococcus granulosus serine:threonine protein kinase 0.0239 0.04 0.04
Schistosoma mansoni protein kinase 0.0768 0.2311 0.2311
Loa Loa (eye worm) hypothetical protein 0.0552 0.1532 0.1532
Trypanosoma cruzi casein kinase, putative 0.0228 0.0359 0.0327
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0669 0.1953 0.1953
Onchocerca volvulus 0.0299 0.0616 0.2275
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0249 0.0436 0.0436
Echinococcus granulosus protein jagged 1 0.0293 0.0593 0.0593
Giardia lamblia Kinase, AGC AKT 0.0245 0.0423 0.0857
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0166 0.0134 0.0134
Onchocerca volvulus 0.0137 0.0031 0.0055
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0328 0.0722 0.0722
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0266 0.0497 0.0497
Echinococcus granulosus rho-associated protein kinase 1 0.0681 0.1996 0.1996
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0166 0.0134 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0154 0.0413
Echinococcus granulosus serine threonine protein kinase nrc 0.0328 0.0722 0.0722
Echinococcus multilocularis casein kinase i 0.0228 0.0359 0.0359
Trichomonas vaginalis glutamate synthase, putative 0.0266 0.0498 0.1511
Echinococcus multilocularis protein jagged 2 0.0293 0.0593 0.0593
Schistosoma mansoni notch 0.0293 0.0593 0.0593
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0212 0.03 0.03
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0553 0.1535 0.1535
Entamoeba histolytica serine/threonine protein kinase, putative 0.0566 0.1581 0.5647
Onchocerca volvulus 0.0137 0.0031 0.0055
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0479 0.1265 0.1265
Plasmodium falciparum glycogen synthase kinase 3 0.027 0.051 0.0479
Trichomonas vaginalis CMGC family protein kinase 0.0176 0.0171 0.0468
Loa Loa (eye worm) hypothetical protein 0.0306 0.064 0.064
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0304 0.0633 0.0633
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0212 0.03 0.03
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0479 0.1265 0.1265
Echinococcus granulosus casein kinase I gamma 0.0447 0.115 0.115
Echinococcus multilocularis titin 0.014 0.0042 0.0042
Entamoeba histolytica cyclin C, putative 0.0898 0.2782 1
Loa Loa (eye worm) TK protein kinase 0.0322 0.0698 0.0698
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1003 0.3162 0.3162
Onchocerca volvulus 0.014 0.0042 0.0095
Echinococcus multilocularis roundabout 2 0.0878 0.2709 0.2709
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0241 0.0408 0.0408
Onchocerca volvulus Neurogenic locus notch homolog 0.0293 0.0593 0.2188
Brugia malayi serine/threonine-protein kinase plk-2 0.0566 0.1581 0.1581
Loa Loa (eye worm) TK/ABL protein kinase 0.0137 0.0031 0.0031
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0228 0.0359 0.0359
Entamoeba histolytica protein kinase domain containing protein 0.021 0.0294 0.0981
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1003 0.3162 0.7281
Echinococcus multilocularis serine:threonine protein kinase N2 0.0271 0.0516 0.0516
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0166 0.0134 0.0134
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0498 0.1511
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0176 0.0171 0.0138
Brugia malayi GCC2 and GCC3 family protein 0.0833 0.2545 0.2545
Echinococcus multilocularis ephrin type A receptor 4 A 0.0202 0.0266 0.0266
Schistosoma mansoni cell adhesion molecule 0.0325 0.0709 0.0709
Echinococcus multilocularis calcium dependent protein kinase 0.0142 0.0049 0.0049
Plasmodium falciparum calcium-dependent protein kinase 4 0.0212 0.03 0.0268
Trypanosoma cruzi cdc2-related kinase 1 0.0249 0.0436 0.0404
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.011 0.011
Echinococcus multilocularis tyrosine protein kinase otk 0.0306 0.064 0.064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0159 0.011 0.011
Brugia malayi hypothetical protein 0.0166 0.0134 0.0134
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0266 0.0498 0.1719
Loa Loa (eye worm) TK/FER protein kinase 0.0137 0.0031 0.0031

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = -9 Concentration required for 50% protection of infected MT-4 cells from wtIIIB-HIV-1-induced cytopathogenicity was determined by the MTT method ChEMBL. 15634015
EC50 (functional) = 0.001 uM Protection of infected MT-4 cells from wtIIIB-HIV-1-induced cytopathogenicity ChEMBL. 15634015
EC50 (functional) = 0.001 uM Concentration required for 50% protection of infected MT-4 cells from wtIIIB-HIV-1-induced cytopathogenicity was determined by the MTT method ChEMBL. 15634015
EC50 (functional) = 0.001 uM Antiviral activity against HIV1 ChEMBL. 16722636
EC50 (functional) = 0.001 uM Protection of infected MT-4 cells from wtIIIB-HIV-1-induced cytopathogenicity ChEMBL. 15634015
EC50 (functional) = 0.001 uM Concentration required for 50% protection of infected MT-4 cells from wtIIIB-HIV-1-induced cytopathogenicity was determined by the MTT method ChEMBL. 15634015
EC50 (functional) = 0.03 uM Concentration required to achieve 50% protection of infected MT-4 cells from Y181C-HIV-1 strain ChEMBL. 15634015
EC50 (functional) = 0.03 uM Compound concentration required to achieve 50% protection of infected MT-4 cells from Y181C strain was determined by the MTT method ChEMBL. 15634015
EC50 (functional) = 0.03 uM Concentration required to achieve 50% protection of infected MT-4 cells from Y181C-HIV-1 strain ChEMBL. 15634015
EC50 (functional) = 0.03 uM Compound concentration required to achieve 50% protection of infected MT-4 cells from Y181C strain was determined by the MTT method ChEMBL. 15634015
EC50 (functional) = 10 uM Concentration required to achieve 50% protection of infected MT-4 cells from K103N-Y181C ChEMBL. 15634015
EC50 (functional) = 10 uM Compound concentration required to achieve 50% protection of infected MT-4 cells from K103N-Y181C strain was determined by the MTT method ChEMBL. 15634015
EC50 (functional) = 10 uM Concentration required to achieve 50% protection of infected MT-4 cells from K103N-Y181C ChEMBL. 15634015
EC50 (functional) = 10 uM Compound concentration required to achieve 50% protection of infected MT-4 cells from K103N-Y181C strain was determined by the MTT method ChEMBL. 15634015
EC90 (functional) = 0.006 uM Concentration required to reduce the amount of p24 by 90% in wtIIIB-HIV-1-infected C8166 cells ChEMBL. 15634015
EC90 (functional) = 0.006 uM Compound concentration required to reduce the amount of p24 by 90% in wtIIIBinfected C8166 cells ChEMBL. 15634015
EC90 (functional) = 0.006 uM Concentration required to reduce the amount of p24 by 90% in wtIIIB-HIV-1-infected C8166 cells ChEMBL. 15634015
EC90 (functional) = 0.006 uM Compound concentration required to reduce the amount of p24 by 90% in wtIIIBinfected C8166 cells ChEMBL. 15634015
EC90 (functional) = 0.2 uM Concentration required to reduce the amount of p24 by 90% in C8166 cells infected with an efavirenz-resistant strain EFVR ChEMBL. 15634015
EC90 (functional) = 0.2 uM Compound concentration required to reduce the amount of p24 by 90% in C8166 cells infected with an efavirenz-resistant strain EFVR carrying mutations K103R, V179D, and P225H ChEMBL. 15634015
EC90 (functional) = 0.2 uM Concentration required to reduce the amount of p24 by 90% in C8166 cells infected with an efavirenz-resistant strain EFVR ChEMBL. 15634015
EC90 (functional) = 0.2 uM Compound concentration required to reduce the amount of p24 by 90% in C8166 cells infected with an efavirenz-resistant strain EFVR carrying mutations K103R, V179D, and P225H ChEMBL. 15634015
Log EC50 (functional) = 9 M Concentration required for 50% protection of infected MT-4 cells from wtIIIB-HIV-1-induced cytopathogenicity was determined by the MTT method ChEMBL. 15634015

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 15634015

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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