Detailed information for compound 312655

Basic information

Technical information
  • TDR Targets ID: 312655
  • Name: 4-(hydrazinecarbonyl)benzenesulfonamide
  • MW: 215.23 | Formula: C7H9N3O3S
  • H donors: 3 H acceptors: 3 LogP: -0.98 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: NNC(=O)c1ccc(cc1)S(=O)(=O)N
  • InChi: 1S/C7H9N3O3S/c8-10-7(11)5-1-3-6(4-2-5)14(9,12)13/h1-4H,8H2,(H,10,11)(H2,9,12,13)
  • InChiKey: JIDAHYHCQJXNTD-UHFFFAOYSA-N  

Network

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Synonyms

  • 4-(aminocarbamoyl)benzenesulfonamide
  • 4-carbazoylbenzenesulfonamide
  • 35264-29-0
  • Benzoic acid, 4-(aminosulfonyl)-, hydrazide
  • NSC252930
  • p-Sulfamylbenzoic acid hydrazide
  • 4-(Hydrazinocarbonyl)benzenesulfonamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References
Homo sapiens carbonic anhydrase IX Starlite/ChEMBL References
Homo sapiens carbonic anhydrase I Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase I 261 aa 281 aa 25.3 %
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0323 0.0702 0.385
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0171 0.0177 0.0177
Loa Loa (eye worm) Notch2 0.0305 0.064 0.0626
Echinococcus multilocularis protein kinase c epsilon type 0.041 0.1001 0.1001
Loa Loa (eye worm) hypothetical protein 0.0314 0.0672 0.0657
Brugia malayi Fes/CIP4 homology domain containing protein 0.0206 0.0298 0.0284
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0177 0.0162
Plasmodium vivax thioredoxin reductase, putative 0.3019 1 1
Onchocerca volvulus 0.0227 0.0373 0.1417
Echinococcus multilocularis mitogen activated protein kinase 11 0.0319 0.0689 0.0689
Schistosoma mansoni tyrosine kinase 0.0606 0.1679 0.1666
Echinococcus granulosus cyclin dependent kinase 5 0.0238 0.0409 0.0409
Schistosoma mansoni serine/threonine kinase 0.0323 0.0702 0.0688
Plasmodium falciparum calcium-dependent protein kinase 3 0.0202 0.0285 0.0245
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0144 0.0085 0.0085
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0144 0.0084 0.0069
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0278 0.0546 0.0508
Brugia malayi Furin-like cysteine rich region family protein 0.0701 0.2008 0.1996
Brugia malayi Protein kinase domain containing protein 0.0229 0.0377 0.0363
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0462 0.1183 0.1183
Echinococcus granulosus tyrosine protein kinase Src64B 0.0308 0.0652 0.0652
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0542 0.146 0.4512
Entamoeba histolytica cyclin C, putative 0.0634 0.1774 1
Echinococcus granulosus tyrosine protein kinase otk 0.0314 0.0672 0.0672
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0308 0.0652 0.0652
Loa Loa (eye worm) hypothetical protein 0.0585 0.1606 0.1593
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0236 0.0403 0.0259
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.068 0.1933 0.192
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Schistosoma mansoni hypothetical protein 0.0144 0.0084 0.0068
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0172 0.0182 0.0182
Loa Loa (eye worm) cyclin domain-containing protein 0.0625 0.1743 0.1729
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0161 0.0144 0.0144
Brugia malayi Protein kinase domain containing protein 0.0344 0.0774 0.0761
Plasmodium falciparum protein kinase 5 0.0238 0.0409 0.037
Loa Loa (eye worm) hypothetical protein 0.0314 0.0672 0.0657
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0214 0.0328 0.0313
Schistosoma mansoni slit 0.0306 0.0642 0.0627
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0251 0.0455 0.0455
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0202 0.0285 0.0245
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0172 0.0182 0.0182
Echinococcus granulosus protein jagged 2 0.0305 0.064 0.064
Echinococcus granulosus protein jagged 1 0.0305 0.064 0.064
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0236 0.0403 0.213
Loa Loa (eye worm) TK protein kinase 0.0185 0.0225 0.0209
Entamoeba histolytica protein kinase 2, putative 0.0314 0.0672 0.3674
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0147 0.0132
Trypanosoma cruzi aurora B kinase, putative 0.0236 0.0403 0.0364
Schistosoma mansoni glutamate synthase 0.0278 0.0546 0.0531
Brugia malayi Kinase associated domain 1 family protein 0.0205 0.0295 0.0281
Brugia malayi Tyrosine-protein kinase abl-1 0.019 0.0242 0.0228
Brugia malayi Protein kinase domain containing protein 0.018 0.0208 0.0194
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0226 0.0369 0.033
Trichomonas vaginalis mercuric reductase, putative 0.1046 0.3196 1
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0444 0.1119 0.1119
Echinococcus granulosus titin 0.0144 0.0084 0.0084
Brugia malayi Protein kinase domain containing protein 0.0163 0.0151 0.0136
Toxoplasma gondii AGC kinase 0.0226 0.0369 0.033
Onchocerca volvulus 0.0144 0.0084 0.0236
Echinococcus granulosus twitchin 0.0776 0.2263 0.2263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0144 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0225 0.0363 0.0348
Echinococcus granulosus leucine rich repeat containing protein 4 0.0144 0.0084 0.0084
Onchocerca volvulus 0.0258 0.0478 0.1846
Echinococcus multilocularis slit 2 protein 0.035 0.0795 0.0795
Echinococcus multilocularis myosin iiia 0.0169 0.0173 0.0173
Brugia malayi Protein kinase domain containing protein 0.0132 0.0045 0.003
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0202 0.0285 0.014
Onchocerca volvulus Netrin receptor homolog 0.0202 0.0284 0.1055
Echinococcus multilocularis nervana 2 0.0249 0.0446 0.0446
Brugia malayi Protein kinase domain containing protein 0.0166 0.0162 0.0147
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0319 0.0689 0.0651
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0278 0.0546 0.1625
Toxoplasma gondii NADPH-glutathione reductase 0.1046 0.3196 0.3169
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Schistosoma mansoni notch 0.0305 0.064 0.0626
Echinococcus granulosus ephrin type A receptor 4 A 0.0194 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0202 0.0285 0.0245
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Schistosoma mansoni serine/threonine kinase 0.0443 0.1118 0.1104
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1046 0.3196 1
Brugia malayi Stress-activated protein kinase jnk-1 0.053 0.1418 0.1405
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Onchocerca volvulus 0.018 0.0208 0.0745
Plasmodium falciparum serine/threonine protein kinase KIN 0.0157 0.0129 0.0088
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0225 0.0363 0.0348
Schistosoma mansoni serine/threonine protein kinase 0.0653 0.184 0.1827
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.1276 0.1262
Echinococcus multilocularis hemicentin 1 0.0314 0.0672 0.0672
Entamoeba histolytica cell division protein kinase 2, putative 0.0238 0.0409 0.2168
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0403 0.0977 0.0977
Echinococcus granulosus tyrosine protein kinase Srms 0.0549 0.1482 0.1482
Brugia malayi Protein kinase domain containing protein 0.086 0.2554 0.2543
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0792 0.2319 0.2319
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.053 0.1418 0.1404
Schistosoma mansoni serine/threonine protein kinase 0.0489 0.1276 0.1262
Echinococcus multilocularis tyrosine protein kinase shark 0.0351 0.0798 0.0798
Schistosoma mansoni titin 0.0144 0.0084 0.0068
Giardia lamblia Glutamate synthase 0.0278 0.0546 0.1282
Entamoeba histolytica protein kinase domain containing protein 0.0131 0.0041 0.0051
Schistosoma mansoni vam6/vps39 related 0.0225 0.0363 0.0348
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.029 0.059 0.059
Plasmodium falciparum calcium-dependent protein kinase 4 0.0202 0.0285 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0359 0.0827 0.2513
Onchocerca volvulus Putative titin 0.0144 0.0084 0.0236
Brugia malayi Protein kinase domain containing protein 0.0589 0.1621 0.1609
Echinococcus multilocularis roundabout 2 0.0333 0.0735 0.0735
Echinococcus granulosus neurogenic locus protein delta 0.0305 0.064 0.064
Brugia malayi Prion-like- 0.0314 0.0672 0.0658
Echinococcus multilocularis cyclin dependent kinase 1 0.0238 0.0409 0.0409
Echinococcus multilocularis calcium dependent protein kinase 0.0136 0.0059 0.0059
Onchocerca volvulus 0.0132 0.0045 0.0078
Loa Loa (eye worm) notch protein 0.0305 0.064 0.0626
Plasmodium vivax serine/threonine kinase-1, putative 0.0308 0.0651 0.0511
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0278 0.0546 0.2953
Echinococcus multilocularis aurora kinase A 0.0236 0.0403 0.0403
Brugia malayi Protein kinase domain containing protein 0.0132 0.0045 0.003
Entamoeba histolytica protein kinase, putative 0.0245 0.0433 0.2305
Plasmodium falciparum glutathione reductase 0.3019 1 1
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0278 0.0546 0.0405
Brugia malayi basement membrane proteoglycan precursor 0.0171 0.0177 0.0162
Echinococcus granulosus nephrin 0.0162 0.0147 0.0147
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0549 0.1635
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0173 0.0157
Echinococcus multilocularis 0.0144 0.0084 0.0084
Trypanosoma cruzi trypanothione reductase, putative 0.3019 1 1
Loa Loa (eye worm) disorganized muscle protein 1 0.0144 0.0084 0.0068
Brugia malayi SH2 domain containing protein 0.0442 0.1115 0.1102
Echinococcus granulosus titin 0.0144 0.0084 0.0084
Echinococcus granulosus casein kinase I alpha 0.0218 0.0339 0.0339
Leishmania major hypothetical protein, conserved 0.0278 0.0546 0.0508
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1893 0.6116 0.611
Giardia lamblia Kinase, CMGC CLK 0.0308 0.0651 0.1627
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0736 0.2128 0.2116
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0278 0.0546 0.0508
Schistosoma mansoni serine/threonine protein kinase 0.0406 0.0991 0.0976
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0669 0.1898 0.1885
Schistosoma mansoni hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0305 0.064 0.0627
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0492 0.1285 0.1285
Plasmodium falciparum thioredoxin reductase 0.3019 1 1
Trichomonas vaginalis STE family protein kinase 0.0172 0.0182 0.0475
Echinococcus granulosus casein kinase I delta 0.0218 0.0339 0.0339
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0166 0.0162 0.0122
Schistosoma mansoni disulfide oxidoreductase 0.0278 0.0546 0.0531
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0708 0.203 0.2017
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0278 0.0546 0.0546
Schistosoma mansoni hypothetical protein 0.0305 0.064 0.0626
Echinococcus multilocularis expressed protein 0.0166 0.0162 0.0162
Schistosoma mansoni g1/s-specific cyclin C 0.1251 0.3905 0.3895
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Echinococcus granulosus neurogenic locus notch protein 4 0.0305 0.064 0.064
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.0285 0.0269
Echinococcus multilocularis serine:threonine protein kinase 38 0.0323 0.0702 0.0702
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Echinococcus multilocularis thioredoxin glutathione reductase 0.3019 1 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0202 0.0285 0.014
Loa Loa (eye worm) TK/ALK protein kinase 0.0307 0.0649 0.0634
Entamoeba histolytica protein kinase domain containing protein 0.0258 0.0478 0.2561
Trichomonas vaginalis STE family protein kinase 0.0172 0.0182 0.0475
Loa Loa (eye worm) hypothetical protein 0.0129 0.0032 0.0017
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0329 0.0724 0.0686
Plasmodium vivax casein kinase 1, putative 0.0218 0.0339 0.0195
Loa Loa (eye worm) hypothetical protein 0.0229 0.0377 0.0362
Schistosoma mansoni serine/threonine protein kinase 0.0433 0.1083 0.1069
Trypanosoma brucei casein kinase I, isoform 2 0.0218 0.0339 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0551 0.1487 0.4599
Echinococcus granulosus NCK adaptor protein 0.0124 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.019 0.0242 0.0227
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0308 0.0652 0.0652
Loa Loa (eye worm) AUR protein kinase 0.0236 0.0403 0.0388
Schistosoma mansoni hypothetical protein 0.0162 0.0147 0.0131
Echinococcus multilocularis transfer RNA-Phe 0.0162 0.0147 0.0147
Echinococcus granulosus roundabout 2 0.0333 0.0735 0.0735
Echinococcus granulosus fibropellin Ia 0.0305 0.064 0.064
Echinococcus multilocularis expressed conserved protein 0.0169 0.0173 0.0173
Brugia malayi Protein kinase domain containing protein 0.0587 0.1612 0.16
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0278 0.0546 0.1625
Echinococcus granulosus hemicentin 1 0.0314 0.0672 0.0672
Schistosoma mansoni protein kinase 0.0532 0.1422 0.1409
Loa Loa (eye worm) AGC/PKA protein kinase 0.0226 0.0369 0.0354
Loa Loa (eye worm) hypothetical protein 0.0386 0.0921 0.0907
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0172 0.0182 0.0182
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0202 0.0285 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.041 0.1001 0.0987
Echinococcus granulosus titin 0.0227 0.0373 0.0373
Onchocerca volvulus 0.0563 0.1531 0.6147
Echinococcus multilocularis twitchin 0.0209 0.0309 0.0309
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0172 0.0182 0.0182
Schistosoma mansoni titin 0.0314 0.0672 0.0657
Schistosoma mansoni protein kinase C mu 0.0437 0.1094 0.108
Onchocerca volvulus 0.0132 0.0045 0.0078
Giardia lamblia High cysteine protein 0.0305 0.064 0.1592
Loa Loa (eye worm) hypothetical protein 0.0737 0.2131 0.2119
Echinococcus multilocularis dual specificity 0.0279 0.0549 0.0549
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0672 0.0658
Loa Loa (eye worm) hypothetical protein 0.0287 0.0579 0.0564
Toxoplasma gondii casein kinase I 0.0218 0.0339 0.03
Echinococcus granulosus insulin growth factor binding 0.0144 0.0084 0.0084
Echinococcus multilocularis 0.0195 0.0259 0.0259
Brugia malayi Cadherin domain containing protein 0.0305 0.0641 0.0627
Giardia lamblia Kinase, CMGC GSK 0.0258 0.0478 0.1057
Entamoeba histolytica protein kinase , putative 0.0236 0.0403 0.213
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0157 0.0129 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0542 0.146 0.1446
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0314 0.0672 0.0634
Loa Loa (eye worm) AUR protein kinase 0.0236 0.0403 0.0388
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0328 0.0312
Brugia malayi Immunoglobulin I-set domain containing protein 0.0189 0.024 0.0226
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0308 0.0651 0.0636
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0278 0.0546 0.1625
Brugia malayi Protein kinase domain containing protein 0.0901 0.2695 0.2685
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0314 0.0672 0.0657
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0169 0.0173 0.0133
Brugia malayi probable protein kinase 0.0532 0.1422 0.141
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Brugia malayi EGF-like domain containing protein 0.0305 0.064 0.0627
Brugia malayi intracellular kinase 0.0258 0.0478 0.0464
Loa Loa (eye worm) hypothetical protein 0.0179 0.0207 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Echinococcus multilocularis Immunoglobulin subtype 0.0171 0.0177 0.0177
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0162 0.0147 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0549 0.0534
Treponema pallidum NADH oxidase 0.1046 0.3196 1
Schistosoma mansoni atypical protein kinase C 0.0586 0.1609 0.1596
Brugia malayi Thioredoxin reductase 0.3019 1 1
Loa Loa (eye worm) hypothetical protein 0.0567 0.1544 0.1531
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0249 0.0446 0.0446
Brugia malayi protein-tyrosine kinase 0.0251 0.0455 0.0441
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1046 0.3196 1
Echinococcus multilocularis tyrosine kinase 0.0132 0.0045 0.0045
Brugia malayi Immunoglobulin I-set domain containing protein 0.0227 0.0373 0.0359
Schistosoma mansoni cell adhesion molecule 0.0171 0.0177 0.0161
Schistosoma mansoni septate junction protein 0.0171 0.0177 0.0161
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0177 0.0162
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0403 0.0978 0.0963
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0373 0.0357
Echinococcus multilocularis neurogenic locus protein delta 0.0305 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0162 0.0147 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0105 0.0089
Trypanosoma cruzi casein kinase, putative 0.0218 0.0339 0.03
Brugia malayi Serine/threonine-protein kinase SULU 0.0446 0.1126 0.1113
Entamoeba histolytica hypothetical protein 0.0389 0.0929 0.515
Loa Loa (eye worm) hypothetical protein 0.0226 0.0369 0.0354
Trypanosoma cruzi casein kinase, putative 0.0218 0.0339 0.03
Echinococcus multilocularis insulin growth factor binding 0.0144 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Loa Loa (eye worm) hypothetical protein 0.0585 0.1606 0.1593
Onchocerca volvulus 0.0279 0.0551 0.2144
Schistosoma mansoni glutamate synthase 0.0278 0.0546 0.0531
Loa Loa (eye worm) AGC/NDR protein kinase 0.0323 0.0702 0.0688
Giardia lamblia Kinase, CMGC CDK 0.0238 0.0409 0.0832
Echinococcus granulosus calcium dependent protein kinase 0.0136 0.0059 0.0059
Loa Loa (eye worm) CDC7 protein kinase 0.018 0.0208 0.0193
Brugia malayi Casein kinase II, alpha chain 0.02 0.028 0.0265
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0278 0.0546 0.0508
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0226 0.0369 0.033
Trypanosoma cruzi hypothetical protein, conserved 0.0278 0.0546 0.0508
Schistosoma mansoni neuroglian 0.0333 0.0735 0.0721
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0489 0.1274 0.1274
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0278 0.0546 0.0508
Brugia malayi Myb-like DNA-binding domain containing protein 0.0144 0.0084 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0651 0.0636
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0226 0.0369 0.033
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0278 0.0546 0.0508
Echinococcus multilocularis tyrosine protein kinase otk 0.0314 0.0672 0.0672
Schistosoma mansoni protein kinase 0.0172 0.0182 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0549 0.1635
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0147 0.0132
Echinococcus granulosus aurora kinase A 0.0236 0.0403 0.0403
Echinococcus multilocularis casein kinase I alpha 0.0218 0.0339 0.0339
Echinococcus multilocularis serine:threonine protein kinase 3 0.0515 0.1366 0.1366
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1046 0.3196 1
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0492 0.1285 0.1285
Echinococcus multilocularis c src tyrosine kinase 0.019 0.0242 0.0242
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0132 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0205 0.0295 0.0279
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0333 0.0735 0.0721
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Brugia malayi Protein kinase domain containing protein 0.0323 0.0702 0.0689
Schistosoma mansoni protein kinase 0.02 0.028 0.0264
Echinococcus granulosus serine threonine protein kinase nrc 0.0314 0.0672 0.0672
Echinococcus multilocularis PAK box P21 Rho binding 0.0129 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Hr1 repeat family protein 0.0584 0.1601 0.1589
Leishmania major protein kinase A catalytic subunit isoform 1 0.0226 0.0369 0.033
Trypanosoma brucei NADH dehydrogenase 0.0278 0.0546 0.0508
Schistosoma mansoni hypothetical protein 0.0305 0.064 0.0626
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0319 0.0689 0.0674
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Echinococcus granulosus cGMP dependent protein kinase 0.0169 0.0173 0.0173
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Echinococcus multilocularis serine:threonine protein kinase N2 0.0261 0.0487 0.0487
Echinococcus granulosus activin receptor type 0.0131 0.0041 0.0041
Giardia lamblia NADH oxidase lateral transfer candidate 0.1046 0.3196 1
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0202 0.0285 0.0271
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0366 0.0852 0.0852
Entamoeba histolytica p21-activated kinase 0.0187 0.0235 0.1165
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0409 0.0394
Echinococcus granulosus casein kinase I alpha 0.0218 0.0339 0.0339
Schistosoma mansoni hypothetical protein 0.0305 0.064 0.0626
Entamoeba histolytica protein kinase domain containing protein 0.0406 0.0991 0.5505
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0218 0.0339 0.0324
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0147 0.0132
Trypanosoma brucei protein kinase, putative 0.0258 0.0478 0.0439
Echinococcus granulosus tyrosine protein kinase Src42A 0.0308 0.0652 0.0652
Brugia malayi Immunoglobulin domain containing protein 0.0171 0.0177 0.0162
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0202 0.0285 0.0285
Echinococcus granulosus protein jagged 2 0.0305 0.064 0.064
Echinococcus granulosus tyrosine protein kinase Src42A 0.0188 0.0236 0.0236
Echinococcus granulosus tyrosine protein kinase Fyn 0.0308 0.0652 0.0652
Loa Loa (eye worm) TK protein kinase 0.051 0.1347 0.1333
Plasmodium falciparum NIMA related kinase 1 0.0273 0.053 0.0491
Plasmodium falciparum calcium-dependent protein kinase 1 0.0202 0.0285 0.0245
Trypanosoma cruzi Protein kinase B 0.0329 0.0724 0.0686
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0442 0.1115 0.1115
Brugia malayi serine/threonine-protein kinase plk-2 0.0542 0.146 0.1447
Schistosoma mansoni tyrosine kinase 0.0701 0.2008 0.1995
Toxoplasma gondii CMGC kinase, CK2 family 0.02 0.028 0.024
Brugia malayi EGF-like domain containing protein 0.035 0.0795 0.0781
Entamoeba histolytica protein kinase domain containing protein 0.02 0.028 0.1424
Echinococcus multilocularis c Jun NH2 terminal kinase 0.053 0.1418 0.1418
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0323 0.0702 0.0702
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0549 0.1635
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0279 0.0549 0.0511
Onchocerca volvulus 0.0563 0.1531 0.6147
Onchocerca volvulus Peroxidasin homolog 0.0144 0.0084 0.0236
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0625 0.1743 0.1743
Loa Loa (eye worm) TK/FER protein kinase 0.0442 0.1115 0.1101
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0333 0.0735 0.0722
Trypanosoma brucei hypothetical protein, conserved 0.0278 0.0546 0.0508
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0278 0.0546 0.0546
Brugia malayi glutamate synthase 0.0278 0.0546 0.0532
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0236 0.0403 0.0403
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0433 0.1083 0.1083
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0162 0.0147 0.0107
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0168 0.0166 0.0126
Trypanosoma cruzi casein kinase II, putative 0.02 0.028 0.024
Echinococcus multilocularis neurogenic locus protein delta 0.0305 0.064 0.064
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0278 0.0546 0.0508
Loa Loa (eye worm) hypothetical protein 0.035 0.0795 0.078
Echinococcus multilocularis casein kinase I gamma 0.0428 0.1064 0.1064
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0278 0.0546 0.0546
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0624 0.1742 0.1742
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0157 0.0129 0.0088
Entamoeba histolytica protein kinase, putative 0.0279 0.0549 0.2971
Schistosoma mansoni serine/threonine protein kinase 0.0792 0.2319 0.2306
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0305 0.064 0.0626
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1046 0.3196 0.3169
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0157 0.0129 0.0088
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0202 0.0285 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0469 0.0453
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Onchocerca volvulus 0.0129 0.0032 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Loa Loa (eye worm) hypothetical protein 0.0205 0.0295 0.0279
Schistosoma mansoni basigin related 0.0171 0.0177 0.0161
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0171 0.0177 0.0177
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0542 0.146 0.1425
Loa Loa (eye worm) hypothetical protein 0.0287 0.0579 0.0564
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0171 0.0177 0.0161
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0353 0.0804 0.079
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0444 0.1119 0.1119
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0163 0.0151 0.0151
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Schistosoma mansoni tyrosine kinase 0.0129 0.0032 0.0016
Onchocerca volvulus 0.0563 0.1531 0.6147
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0328 0.0312
Toxoplasma gondii rhoptry neck protein RON9 0.0563 0.1531 0.1496
Schistosoma mansoni notch 0.0305 0.064 0.0626
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0172 0.0182 0.0182
Schistosoma mansoni tyrosine kinase 0.0284 0.0568 0.0553
Echinococcus granulosus tyrosine protein kinase ABL1 0.0132 0.0045 0.0045
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0278 0.0546 0.0532
Loa Loa (eye worm) hypothetical protein 0.0171 0.0177 0.0161
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0308 0.0651 0.0613
Schistosoma mansoni septate junction protein 0.0171 0.0177 0.0161
Brugia malayi Calcium binding EGF domain containing protein 0.0305 0.064 0.0627
Onchocerca volvulus 0.018 0.0208 0.0745
Brugia malayi Immunoglobulin I-set domain containing protein 0.0188 0.0238 0.0223
Echinococcus multilocularis epidermal growth factor receptor 0.0489 0.1274 0.1274
Schistosoma mansoni protein kinase 0.0444 0.1119 0.1104
Onchocerca volvulus 0.0152 0.0113 0.0358
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0157 0.0129 0.0129
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0366 0.0852 0.0852
Schistosoma mansoni tyrosine kinase 0.0489 0.1274 0.126
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.0403 0.213
Loa Loa (eye worm) hypothetical protein 0.0245 0.0434 0.0419
Entamoeba histolytica protein kinase, putative 0.0245 0.0433 0.2305
Echinococcus granulosus dual specificity 0.0279 0.0549 0.0549
Loa Loa (eye worm) TK/EPH protein kinase 0.023 0.038 0.0365
Brugia malayi Peroxidasin 0.0315 0.0674 0.066
Echinococcus multilocularis neurogenic locus notch protein 0.0305 0.064 0.064
Echinococcus granulosus serine:threonine protein kinase 0.0229 0.0377 0.0377
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0308 0.0652 0.0652
Echinococcus granulosus casein kinase I gamma 0.0428 0.1064 0.1064
Echinococcus multilocularis casein kinase i 0.0218 0.0339 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0433 0.0418
Echinococcus multilocularis neural cadherin 0.0305 0.0641 0.0641
Brugia malayi Protein kinase domain containing protein 0.0435 0.109 0.1077
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0278 0.0546 0.0405
Trichomonas vaginalis AGC family protein kinase 0.0226 0.0369 0.1067
Plasmodium vivax ferrodoxin reductase, putative 0.0278 0.0546 0.0405
Echinococcus multilocularis carbonic anhydrase II 0.0214 0.0328 0.0328
Brugia malayi Egg laying defective protein 4 0.0169 0.0173 0.0158
Echinococcus multilocularis titin 0.0144 0.0084 0.0084
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0229 0.0377 0.0362
Echinococcus granulosus serine:threonine protein kinase N2 0.0261 0.0487 0.0487
Echinococcus multilocularis ephrin type A receptor 4 A 0.0194 0.0259 0.0259
Brugia malayi protein kinase C II. 0.041 0.1001 0.0988
Loa Loa (eye worm) hypothetical protein 0.0202 0.0285 0.0269
Schistosoma mansoni hypothetical protein 0.0305 0.064 0.0626
Brugia malayi basement membrane proteoglycan 0.0171 0.0177 0.0162
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0792 0.2319 0.2319
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0466 0.1195 0.1181
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0171 0.0177 0.0177
Brugia malayi Protein kinase domain containing protein 0.0708 0.203 0.2018
Loa Loa (eye worm) TK/ABL protein kinase 0.0132 0.0045 0.0029
Brugia malayi Protein kinase domain containing protein 0.0307 0.0649 0.0635
Echinococcus multilocularis 0.0243 0.0425 0.0425
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0202 0.0285 0.0245
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0168 0.0166 0.0126
Leishmania major protein kinase, putative 0.0308 0.0651 0.0613
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0168 0.0166 0.0126
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0437 0.2327
Trichomonas vaginalis apoptosis inducing factor, putative 0.0278 0.0546 0.1625
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0208 0.0557
Brugia malayi Prion-like- 0.0144 0.0084 0.0069
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0314 0.0672 0.0672
Echinococcus multilocularis notch 0.0305 0.064 0.064
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0214 0.0328 0.0313
Plasmodium falciparum casein kinase 1 0.0218 0.0339 0.03
Entamoeba histolytica PH domain containing protein kinase, putative 0.0242 0.0422 0.224
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0258 0.0478 0.0463
Loa Loa (eye worm) TK protein kinase 0.0251 0.0455 0.044
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0344 0.0774 0.076
Entamoeba histolytica casein kinase, putative 0.0218 0.0339 0.1765
Loa Loa (eye worm) hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0672 0.0658
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0737 0.2131 0.2131
Schistosoma mansoni titin 0.0144 0.0084 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0651 0.0636
Echinococcus granulosus slit 2 protein 0.035 0.0795 0.0795
Schistosoma mansoni glutamate synthase 0.0278 0.0546 0.0531
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0258 0.0478 0.0439
Schistosoma mansoni hypothetical protein 0.0205 0.0295 0.0279
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0736 0.2128 0.2128
Schistosoma mansoni myosin-binding protein-related 0.0162 0.0147 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0651 0.1957
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0249 0.0446 0.0446
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0708 0.203 0.203
Entamoeba histolytica PH domain containing protein kinase, putative 0.0242 0.0422 0.224
Brugia malayi GCC2 and GCC3 family protein 0.0868 0.2583 0.2572
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.023 0.0214
Loa Loa (eye worm) hypothetical protein 0.0927 0.2787 0.2776
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0225 0.0363 0.0348
Brugia malayi EGF-like domain containing protein 0.0305 0.064 0.0627
Plasmodium vivax unspecified product 0.02 0.028 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0208 0.0557
Schistosoma mansoni titin 0.0162 0.0147 0.0131
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0489 0.1276 0.1276
Loa Loa (eye worm) AGC/AKT protein kinase 0.0587 0.1612 0.1599
Trichomonas vaginalis CAMK family protein kinase 0.0542 0.146 0.4512
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0333 0.0735 0.0735
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0151 0.0108 0.0093
Schistosoma mansoni protein kinase 0.0871 0.2594 0.2582
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Echinococcus granulosus mitogen activated protein kinase 14 0.0319 0.0689 0.0689
Schistosoma mansoni tyrosine kinase 0.0423 0.1047 0.1033
Trichomonas vaginalis glutamate synthase, putative 0.0278 0.0546 0.1625
Echinococcus granulosus Vam6:Vps39 protein 0.0225 0.0363 0.0363
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0278 0.0546 0.0508
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0542 0.146 0.146
Schistosoma mansoni titin 0.0227 0.0373 0.0357
Onchocerca volvulus 0.0386 0.0921 0.3657
Echinococcus multilocularis protein kinase c iota type 0.0574 0.1567 0.1567
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0567 0.1543 0.1529
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Loa Loa (eye worm) hypothetical protein 0.0377 0.0888 0.0874
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0245 0.0433 0.0394
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0245 0.0433 0.0394
Schistosoma mansoni cell adhesion molecule 0.0333 0.0735 0.0721
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Brugia malayi protein kinase C3,putative 0.0316 0.0679 0.0665
Entamoeba histolytica protein kinase, putative 0.0236 0.0403 0.213
Brugia malayi Protein kinase domain containing protein 0.0329 0.0723 0.071
Leishmania major trypanothione reductase 0.3019 1 1
Trichomonas vaginalis STE family protein kinase 0.0169 0.0173 0.0445
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Giardia lamblia Kinase, AGC PKA 0.0314 0.0672 0.1695
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0333 0.0735 0.0735
Leishmania major hypothetical protein, conserved 0.0278 0.0546 0.0508
Trichomonas vaginalis CMGC family protein kinase 0.0168 0.0166 0.0425
Echinococcus granulosus calcium activated potassium channel 0.027 0.0521 0.0521
Schistosoma mansoni hypothetical protein 0.0144 0.0084 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Brugia malayi Variant SH3 domain containing protein 0.0124 0.0016 0.0001
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0171 0.0177 0.0177
Schistosoma mansoni tyrosine kinase 0.019 0.0242 0.0227
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.147 0.4659 0.4659
Echinococcus multilocularis casein kinase ii subunit alpha 0.02 0.028 0.028
Loa Loa (eye worm) TK/INSR protein kinase 0.0606 0.1679 0.1666
Echinococcus granulosus cyclin dependent kinase 0.0238 0.0409 0.0409
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0235 0.0397 0.0383
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0278 0.0546 0.0546
Loa Loa (eye worm) hypothetical protein 0.0315 0.0674 0.0659
Echinococcus multilocularis mitogen activated protein kinase 3 0.0168 0.0166 0.0166
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0278 0.0546 0.2953
Loa Loa (eye worm) hypothetical protein 0.0305 0.0641 0.0626
Echinococcus multilocularis nervana 2 0.0249 0.0446 0.0446
Echinococcus granulosus N chimaerin 0.0151 0.0108 0.0108
Echinococcus granulosus Immunoglobulin 0.0567 0.1543 0.1543
Schistosoma mansoni protein kinase 0.0307 0.0647 0.0633
Echinococcus granulosus cGMP dependent protein kinase 1 0.0169 0.0173 0.0173
Echinococcus granulosus Protein kinase C brain isozyme 0.0489 0.1276 0.1276
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0189 0.024 0.024
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0319 0.0689 0.0651
Loa Loa (eye worm) carbonic anhydrase 3 0.0214 0.0328 0.0312
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.02 0.028 0.0264
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0329 0.0723 0.0723
Echinococcus multilocularis tyrosine protein kinase Blk 0.0251 0.0455 0.0455
Schistosoma mansoni cell adhesion molecule 0.0162 0.0147 0.0131
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0162 0.0147 0.0107
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0567 0.1543 0.1529
Loa Loa (eye worm) hypothetical protein 0.0279 0.0551 0.0536
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Schistosoma mansoni rap gtpase-activating protein 0.0225 0.0363 0.0348
Echinococcus multilocularis dual specificity 0.0279 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1046 0.3196 0.3196
Echinococcus granulosus cyclin dependent kinase 1 0.0238 0.0409 0.0409
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0245 0.0433 0.0394
Brugia malayi cell division control protein 2 homolog 0.0238 0.0409 0.0395
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0871 0.2594 0.2594
Onchocerca volvulus Serine\/threonine kinase homolog 0.0542 0.146 0.5855
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Entamoeba histolytica protein kinase, putative 0.0132 0.0044 0.0072
Schistosoma mansoni cell adhesion molecule 0.0756 0.2194 0.2182
Onchocerca volvulus 0.0132 0.0045 0.0078
Loa Loa (eye worm) TK protein kinase 0.0311 0.066 0.0645
Loa Loa (eye worm) projectin 0.0162 0.0147 0.0131
Schistosoma mansoni titin 0.0144 0.0084 0.0068
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0157 0.0129 0.0113
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0157 0.0129 0.0088
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0278 0.0546 0.0546
Brugia malayi Cyclin C 0.1251 0.3905 0.3896
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0328 0.0288
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0171 0.0177 0.0161
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0792 0.2319 0.2306
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0202 0.0285 0.014
Echinococcus multilocularis mitogen activated protein kinase 11 0.0319 0.0689 0.0689
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0462 0.1183 0.1183
Echinococcus granulosus c src tyrosine kinase 0.019 0.0242 0.0242
Plasmodium falciparum cGMP-dependent protein kinase 0.0169 0.0173 0.0133
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0279 0.0549 0.0511
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0278 0.0546 0.0508
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0278 0.0546 0.2953
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0255 0.0469 0.0469
Echinococcus granulosus protein kinase c iota type 0.0574 0.1567 0.1567
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0278 0.0546 0.1625
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0225 0.0363 0.0363
Echinococcus granulosus mitogen activated protein kinase 3 0.0168 0.0166 0.0166
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0278 0.0546 0.2953
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0308 0.0651 0.0613
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0672 0.0658
Entamoeba histolytica casein kinase, putative 0.02 0.028 0.1424
Loa Loa (eye worm) TK protein kinase 0.0376 0.0885 0.087
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0255 0.0469 0.0455
Brugia malayi Protein kinase domain containing protein 0.0283 0.0566 0.0552
Schistosoma mansoni tyrosine kinase 0.0308 0.0652 0.0637
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Schistosoma mansoni sulfide quinone reductase 0.0278 0.0546 0.0531
Trypanosoma cruzi polo-like protein kinase, putative 0.0542 0.146 0.1425
Schistosoma mansoni serine/threonine protein kinase 0.053 0.1418 0.1404
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0384 0.1112
Schistosoma mansoni serine/threonine protein kinase 0.0428 0.1064 0.105
Echinococcus multilocularis netrin receptor unc 5 0.0229 0.0377 0.0377
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0901 0.2695 0.2684
Schistosoma mansoni cell adhesion molecule 0.0171 0.0177 0.0161
Entamoeba histolytica casein kinase 1, putative 0.0218 0.0339 0.1765
Schistosoma mansoni protein kinase 0.0218 0.0339 0.0324
Loa Loa (eye worm) CAMK protein kinase 0.0227 0.0373 0.0357
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0285 0.08
Echinococcus granulosus protein tyrosine kinase 0.0583 0.16 0.16
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0567 0.1543 0.1543
Echinococcus multilocularis rac serine:threonine kinase 0.0329 0.0724 0.0724
Echinococcus granulosus Glutaredoxin protein 5 0.0249 0.0446 0.0446
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Schistosoma mansoni vav2 0.0166 0.0161 0.0145
Toxoplasma gondii selenide, water dikinase 0.0278 0.0546 0.0508
Schistosoma mansoni basigin related 0.0171 0.0177 0.0161
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0129 0.0113
Giardia lamblia Kinase, CMGC CK2 0.02 0.028 0.0406
Brugia malayi Protein kinase domain containing protein 0.0403 0.0978 0.0964
Trichomonas vaginalis CK1 family protein kinase 0.0218 0.0339 0.0971
Brugia malayi Immunoglobulin I-set domain containing protein 0.0333 0.0735 0.0722
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0218 0.0339 0.03
Echinococcus granulosus glutamate synthase 0.0278 0.0546 0.0546
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0669 0.1898 0.1886
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0305 0.064 0.251
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0245 0.0433 0.0418
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0171 0.0177 0.0161
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0226 0.0369 0.0355
Loa Loa (eye worm) hypothetical protein 0.0377 0.0888 0.0874
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0279 0.0549 0.0511
Loa Loa (eye worm) AGC/PKA protein kinase 0.0226 0.0369 0.0354
Brugia malayi phosphoinositide-dependent protein kinase I 0.0163 0.0151 0.0136
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0255 0.0469 0.0469
Echinococcus multilocularis cyclin 0.0625 0.1743 0.1743
Echinococcus granulosus serine:threonine protein kinase 0.0229 0.0377 0.0377
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0406 0.0991 0.0991
Echinococcus multilocularis serine:threonine protein kinase 0.0229 0.0377 0.0377
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1046 0.3196 0.3169
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0466 0.1196 0.1196
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0163 0.0151 0.0151
Schistosoma mansoni hypothetical protein 0.0144 0.0084 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Giardia lamblia Kinase, NEK 0.0273 0.053 0.1228
Brugia malayi SH2 domain containing protein 0.0132 0.0045 0.003
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0279 0.0549 0.0534
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0202 0.0285 0.0285
Loa Loa (eye worm) TK/KIN16 protein kinase 0.143 0.4522 0.4513
Loa Loa (eye worm) hypothetical protein 0.0171 0.0177 0.0161
Echinococcus granulosus netrin receptor unc 5 0.0229 0.0377 0.0377
Leishmania major protein kinase, putative 0.0169 0.0173 0.0133
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0144 0.0084 0.0068
Brugia malayi EGF-like domain containing protein 0.0305 0.064 0.0627
Echinococcus multilocularis insulin receptor 0.0606 0.1679 0.1679
Schistosoma mansoni hypothetical protein 0.0278 0.0546 0.0531
Echinococcus multilocularis neurogenic locus notch protein 0.0305 0.064 0.064
Schistosoma mansoni tyrosine kinase 0.0351 0.0798 0.0783
Trichomonas vaginalis CAMK family protein kinase 0.0435 0.109 0.3344
Onchocerca volvulus 0.0144 0.0084 0.0236
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0308 0.0652 0.0652
Loa Loa (eye worm) hypothetical protein 0.0868 0.2583 0.2571
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0278 0.0546 0.0546
Trichomonas vaginalis AGC family protein kinase 0.0344 0.0774 0.2347
Onchocerca volvulus 0.0162 0.0147 0.0495
Entamoeba histolytica protein kinase, putative 0.0587 0.1612 0.9074
Echinococcus granulosus nervana 2 0.0249 0.0446 0.0446
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0278 0.0546 0.0508
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0209 0.031 0.031
Echinococcus multilocularis serine:threonine protein kinase N2 0.0584 0.1601 0.1601
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0162 0.0146
Echinococcus multilocularis peroxidasin 0.0315 0.0674 0.0674
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1046 0.3196 0.2803
Trichomonas vaginalis CK1 family protein kinase 0.0218 0.0339 0.0971
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Echinococcus granulosus serine:threonine protein kinase N2 0.0584 0.1601 0.1601
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0542 0.146 0.146
Echinococcus multilocularis dual specificity protein kinase clk2 0.0308 0.0651 0.0651
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Schistosoma mansoni notch 0.0305 0.064 0.0626
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0278 0.0546 0.0546
Leishmania major protein kinase, putative 0.0202 0.0285 0.0245
Schistosoma mansoni titin 0.0144 0.0084 0.0068
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0188 0.0236 0.0236
Trichomonas vaginalis CK1 family protein kinase 0.0218 0.0339 0.0971
Trypanosoma brucei polo-like protein kinase 0.0542 0.146 0.1425
Echinococcus granulosus lachesin 0.0314 0.0672 0.0672
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0169 0.0173 0.0809
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0319 0.0689 0.0651
Brugia malayi ephrin receptor 1 precursor 0.0126 0.0024 0.0009
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0226 0.0369 0.033
Trichomonas vaginalis CMGC family protein kinase 0.0238 0.0409 0.1193
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0549 0.1635
Schistosoma mansoni notch 0.0305 0.064 0.0626
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0278 0.0546 0.0546
Schistosoma mansoni hypothetical protein 0.0144 0.0084 0.0068
Brugia malayi Protein kinase domain 0.0172 0.0182 0.0168
Schistosoma mansoni cell adhesion molecule 0.0314 0.0672 0.0657
Giardia lamblia Kinase, CMGC CDK 0.0238 0.0409 0.0832
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0202 0.0285 0.0285
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0163 0.0151 0.0135
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0245 0.0433 0.0394
Trichomonas vaginalis CAMK family protein kinase 0.0542 0.146 0.4512
Onchocerca volvulus 0.0144 0.0084 0.0236
Leishmania major casein kinase II, putative 0.02 0.028 0.024
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1046 0.3196 0.3169
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0162 0.0147 0.0131
Schistosoma mansoni tyrosine kinase 0.0407 0.0993 0.0978
Brugia malayi Protein kinase domain containing protein 0.0238 0.0409 0.0395
Toxoplasma gondii AGC kinase 0.0226 0.0369 0.033
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0278 0.0546 0.0508
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0202 0.0285 0.0269
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0278 0.0546 0.0508
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Echinococcus granulosus titin 0.0144 0.0084 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0708 0.203 0.2017
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0166 0.0162 0.0122
Entamoeba histolytica thioredoxin reductase, putative 0.0278 0.0546 0.2953
Brugia malayi Protein kinase domain containing protein 0.1893 0.6116 0.611
Echinococcus granulosus casein kinase ii subunit alpha 0.02 0.028 0.028
Trypanosoma brucei aurora B kinase 0.0236 0.0403 0.0364
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0645 0.1814 0.1801
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0226 0.0369 0.033
Schistosoma mansoni kinase 0.058 0.1587 0.1574
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0231 0.0384 0.0384
Trypanosoma cruzi cdc2-related kinase 1 0.0238 0.0409 0.037
Brugia malayi Delta serrate ligand family protein 0.0305 0.064 0.0627
Onchocerca volvulus 0.0305 0.064 0.251
Onchocerca volvulus 0.0278 0.0546 0.2125
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0278 0.0546 0.0532
Schistosoma mansoni nephrin 0.0333 0.0735 0.0721
Trichomonas vaginalis CAMK family protein kinase 0.0542 0.146 0.4512
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0168 0.0166 0.0126
Onchocerca volvulus 0.0563 0.1531 0.6147
Echinococcus multilocularis Immunoglobulin 0.0171 0.0177 0.0177
Echinococcus granulosus dual specificity 0.0245 0.0433 0.0433
Onchocerca volvulus 0.0287 0.0579 0.2258
Brugia malayi Immunoglobulin I-set domain containing protein 0.143 0.4522 0.4514
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0168 0.0166 0.0126
Schistosoma mansoni tyrosine kinase 0.0366 0.0852 0.0837
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1046 0.3196 0.3095
Echinococcus multilocularis epidermal growth factor receptor 0.0701 0.2008 0.2008
Plasmodium falciparum thioredoxin reductase 0.1046 0.3196 0.3169
Schistosoma mansoni hemicentin 0.0162 0.0147 0.0131
Schistosoma mansoni protein kinase 0.0871 0.2594 0.2582
Trichomonas vaginalis STE family protein kinase 0.0172 0.0182 0.0475
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi Sushi domain 0.0563 0.1531 0.1519
Loa Loa (eye worm) TK/FAK protein kinase 0.0589 0.1621 0.1608
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0323 0.0702 0.0702
Entamoeba histolytica protein kinase, putative 0.0204 0.0294 0.1504
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0433 0.1083 0.1083
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0645 0.1814 0.1801
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.0377 0.1091
Schistosoma mansoni cell adhesion molecule 0.0333 0.0735 0.0721
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0339 0.0324
Brugia malayi Protein kinase domain containing protein 0.0428 0.1064 0.1051
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0278 0.0546 0.1625
Toxoplasma gondii AGC kinase 0.0571 0.156 0.1525
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0433 0.1083 0.1083
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.0384 0.1112
Mycobacterium tuberculosis Probable oxidoreductase 0.1046 0.3196 0.2803
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1046 0.3196 0.3169
Schistosoma mansoni netrin receptor unc5 0.0171 0.0177 0.0161
Schistosoma mansoni c4b-binding protein beta chain 0.0563 0.1531 0.1518
Brugia malayi RhoGAP domain containing protein 0.0151 0.0108 0.0094
Loa Loa (eye worm) hypothetical protein 0.0626 0.1749 0.1736
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0238 0.0409 0.0394
Brugia malayi casein kinase 1, delta 0.0218 0.0339 0.0325
Onchocerca volvulus Neurogenic locus notch homolog 0.0305 0.064 0.251
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0148 0.0098 0.0082
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0168 0.0166 0.0151
Onchocerca volvulus 0.0144 0.0084 0.0236
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0202 0.0285 0.0269
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0278 0.0546 0.1625
Plasmodium vivax serine/threonine protein kinase, putative 0.0166 0.0162 0.0015
Echinococcus granulosus casein kinase i 0.0218 0.0339 0.0339
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0314 0.0672 0.0657
Echinococcus multilocularis N chimaerin 0.0151 0.0108 0.0108
Schistosoma mansoni nephrin related 0.0144 0.0084 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0163 0.0151 0.0376
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Entamoeba histolytica protein kinase, putative 0.0144 0.0084 0.0302
Echinococcus multilocularis C type lectin domian containing protein 0.0563 0.1531 0.1531
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0308 0.0651 0.0613
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Toxoplasma gondii histone kinase SNF1, putative 0.0157 0.0129 0.0088
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Entamoeba histolytica protein kinase domain containing protein 0.0258 0.0478 0.2561
Trichomonas vaginalis glutathione reductase, putative 0.1046 0.3196 1
Plasmodium vivax glutathione reductase, putative 0.3019 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0238 0.0409 0.0394
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0333 0.0735 0.0735
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0278 0.0549 0.1633
Schistosoma mansoni basigin related 0.0171 0.0177 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0168 0.0166 0.0425
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0147 0.0132
Brugia malayi EGF-like domain containing protein 0.0305 0.064 0.0627
Trypanosoma brucei Casein kinase II 0.02 0.028 0.024
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0708 0.203 0.8185
Schistosoma mansoni serine/threonine protein kinase 0.086 0.2554 0.2542
Schistosoma mansoni protein kinase 0.0444 0.1119 0.1104
Brugia malayi Prion-like- 0.0144 0.0084 0.0069
Loa Loa (eye worm) hypothetical protein 0.0132 0.0045 0.0029
Schistosoma mansoni netrin receptor unc5 0.0229 0.0377 0.0362
Brugia malayi serine/threonine protein kinase 6 0.0236 0.0403 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0208 0.0193
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0151 0.0108 0.0093
Echinococcus granulosus serine:threonine kinase SAD 1 0.0157 0.0129 0.0129
Echinococcus granulosus neural cadherin 0.0305 0.0641 0.0641
Schistosoma mansoni protein kinase 0.0172 0.0182 0.0167
Schistosoma mansoni septate junction protein 0.0314 0.0672 0.0657
Brugia malayi Fibronectin type III domain containing protein 0.0585 0.1606 0.1594
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0333 0.0735 0.0735
Plasmodium falciparum ferrodoxin reductase-like protein 0.0278 0.0546 0.0508
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0308 0.0651 0.0613
Plasmodium vivax apical sushi protein, putative 0.0563 0.1531 0.1404
Echinococcus multilocularis lachesin 0.0314 0.0672 0.0672
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0625 0.1743 0.1743
Onchocerca volvulus 0.0563 0.1531 0.6147
Toxoplasma gondii rhoptry neck protein RON1 0.0563 0.1531 0.1496
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0403 0.1172
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Schistosoma mansoni tyrosine kinase 0.0583 0.16 0.1586
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Echinococcus granulosus fibroblast growth factor receptor 4 0.0366 0.0852 0.0852
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0226 0.0369 0.033
Onchocerca volvulus 0.0305 0.064 0.251
Brugia malayi Protein kinase domain containing protein 0.0132 0.0045 0.003
Echinococcus multilocularis dual specificity 0.0279 0.0549 0.0549
Brugia malayi Protein kinase domain containing protein 0.0245 0.0433 0.0419
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Echinococcus granulosus tyrosine protein kinase Blk 0.0251 0.0455 0.0455
Schistosoma mansoni tyrosine kinase 0.0308 0.0652 0.0637
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0403 0.0388
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0278 0.0546 0.0508
Brugia malayi Animal haem peroxidase family protein 0.0144 0.0084 0.0069
Echinococcus granulosus titin 0.0227 0.0373 0.0373
Echinococcus multilocularis tyrosine protein kinase Abl 0.019 0.0242 0.0242
Trypanosoma cruzi NADH dehydrogenase, putative 0.0278 0.0546 0.0508
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0278 0.0546 0.1282
Brugia malayi Heparan sulfate 0.0171 0.0177 0.0162
Brugia malayi P38 map kinase family protein 2 0.0319 0.0689 0.0675
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Schistosoma mansoni hypothetical protein 0.0225 0.0363 0.0348
Entamoeba histolytica serine/threonine protein kinase, putative 0.0542 0.146 0.8197
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Brugia malayi protein unc-22 0.0227 0.0373 0.0359
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Schistosoma mansoni protein kinase 0.0131 0.0041 0.0025
Giardia lamblia Thioredoxin reductase 0.0278 0.0546 0.1282
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0309 0.0294
Trypanosoma brucei protein kinase, putative 0.0176 0.0194 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Toxoplasma gondii thioredoxin reductase 0.3019 1 1
Loa Loa (eye worm) hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Temporarily assigned gene name protein 59 0.0225 0.0363 0.0349
Echinococcus granulosus neuroglian 0.0333 0.0735 0.0735
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0329 0.0723 0.0709
Loa Loa (eye worm) hypothetical protein 0.0645 0.1814 0.1801
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1046 0.3196 0.3186
Trichomonas vaginalis AGC family protein kinase 0.0331 0.073 0.2206
Echinococcus multilocularis casein kinase I alpha 0.0218 0.0339 0.0339
Echinococcus multilocularis cyclin dependent kinase 5 0.0238 0.0409 0.0409
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0549 0.1635
Onchocerca volvulus Serine\/threonine kinase homolog 0.0329 0.0723 0.2849
Onchocerca volvulus 0.0144 0.0084 0.0236
Schistosoma mansoni hypothetical protein 0.0305 0.064 0.0626
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0314 0.0672 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0147 0.0132
Entamoeba histolytica protein kinase, putative 0.0166 0.0162 0.0747
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.041 0.1001 0.0987
Trichomonas vaginalis AGC family protein kinase 0.0163 0.0151 0.0376
Brugia malayi Protein kinase domain containing protein 0.0387 0.0922 0.0909
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1046 0.3196 1
Schistosoma mansoni serine/threonine-protein kinase 0.0329 0.0724 0.071
Echinococcus granulosus basement membrane specific heparan sulfate 0.0171 0.0177 0.0177
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0226 0.0369 0.033
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Plasmodium falciparum serine/threonine protein kinase 0.0166 0.0162 0.0122
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0258 0.0478 0.0463
Echinococcus granulosus mitogen activated protein kinase 11 0.0319 0.0689 0.0689
Loa Loa (eye worm) hypothetical protein 0.0881 0.2626 0.2614
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0144 0.0084 0.0084
Brugia malayi Prion-like- 0.0144 0.0084 0.0069
Brugia malayi Protein kinase domain containing protein 0.0645 0.1814 0.1802
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1046 0.3196 1
Trypanosoma brucei carbonic anhydrase-like protein 0.0214 0.0328 0.0288
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0406 0.0991 0.0976
Trypanosoma cruzi hypothetical protein, conserved 0.0278 0.0546 0.0508
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1046 0.3196 0.3169
Loa Loa (eye worm) thioredoxin reductase 0.3019 1 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.0202 0.0285 0.0245
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Onchocerca volvulus 0.0132 0.0045 0.0078
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1046 0.3196 0.3169
Schistosoma mansoni peroxidasin 0.0171 0.0179 0.0163
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0278 0.0546 0.1625
Leishmania major hypothetical protein, conserved 0.0278 0.0546 0.0508
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0166 0.0162 0.0122
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0144 0.0084 0.0068
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0462 0.1359
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0708 0.203 0.2017
Trichomonas vaginalis CMGC family protein kinase 0.0279 0.0549 0.1635
Giardia lamblia Kinase, STE STE20 0.0169 0.0173 0.0054
Echinococcus granulosus Immunoglobulin 0.0171 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Leishmania major protein kinase, putative 0.0236 0.0403 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.0253 0.0462 0.1359
Trypanosoma cruzi casein kinase, putative 0.0218 0.0339 0.03
Entamoeba histolytica protein kinase, putative 0.0166 0.0162 0.0747
Trichomonas vaginalis CMGC family protein kinase 0.0168 0.0166 0.0425
Plasmodium falciparum serine/threonine protein kinase, putative 0.0236 0.0403 0.0364
Loa Loa (eye worm) cyclin C 0.1251 0.3905 0.3895
Onchocerca volvulus 0.0225 0.0363 0.1378
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0227 0.0373 0.0357
Brugia malayi hypothetical protein 0.0446 0.1126 0.1113
Plasmodium vivax glycogen synthase kinase 3, putative 0.0258 0.0478 0.0335
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Echinococcus granulosus insulin receptor 0.0606 0.1679 0.1679
Echinococcus granulosus low density lipoprotein receptor ldl 0.0171 0.0177 0.0177
Echinococcus multilocularis neuroglian 0.0333 0.0735 0.0735
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0768 0.2239 0.2227
Brugia malayi Leucine Rich Repeat family protein 0.0144 0.0085 0.0071
Echinococcus granulosus defective proboscis extension response 0.0567 0.1543 0.1543
Onchocerca volvulus 0.0305 0.064 0.251
Brugia malayi hypothetical protein 0.0171 0.0177 0.0162
Loa Loa (eye worm) hypothetical protein 0.0602 0.1664 0.1651
Brugia malayi MAP kinase sur-1 0.0168 0.0166 0.0152
Schistosoma mansoni hypothetical protein 0.0305 0.0641 0.0626
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0406 0.0991 0.0977
Echinococcus multilocularis neurogenic locus notch protein 4 0.0305 0.064 0.064
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0314 0.0672 0.2639
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0278 0.0546 0.0546
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0208 0.0557
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0278 0.0546 0.1625
Brugia malayi Protein kinase c protein 2 0.0232 0.0388 0.0374
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0258 0.0478 0.0478
Schistosoma mansoni septate junction protein 0.0305 0.064 0.0626
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Echinococcus multilocularis cyclin dependent kinase 0.0238 0.0409 0.0409
Plasmodium vivax protein kinase Crk2 0.0238 0.0409 0.0266
Echinococcus granulosus serine:threonine protein kinase 3 0.0515 0.1366 0.1366
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0169 0.0173 0.0809
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0314 0.0672 0.0672
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0437 0.1094 0.1081
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.1215 0.1201
Echinococcus granulosus tyrosine protein kinase HCK 0.0185 0.0225 0.0225
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0171 0.0177 0.0161
Schistosoma mansoni vesicular amine transporter 0.0567 0.1543 0.1529
Entamoeba histolytica protein kinase, putative 0.0236 0.0403 0.213
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.0549 0.2971
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0308 0.0652 0.0652
Brugia malayi C1-like domain containing protein 0.0437 0.1094 0.1081
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0472 0.1215 0.1215
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0308 0.0651 0.0613
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0314 0.0672 0.0657
Giardia lamblia Kinase, AGC PKA 0.0226 0.0369 0.0701
Brugia malayi EGF-like domain containing protein 0.0305 0.064 0.0627
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0369 0.0354
Echinococcus multilocularis roundabout 2 0.0899 0.2689 0.2689
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0171 0.0177 0.0177
Brugia malayi Cadherin domain containing protein 0.0305 0.0641 0.0627
Echinococcus granulosus tyrosine protein kinase shark 0.0351 0.0798 0.0798
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0278 0.0546 0.1625
Loa Loa (eye worm) hypothetical protein 0.0314 0.0672 0.0657
Echinococcus granulosus cyclin dependent kinase 19 0.086 0.2554 0.2554
Echinococcus multilocularis growth factor receptor bound protein 2 0.0124 0.0016 0.0016
Echinococcus multilocularis calcium activated potassium channel 0.027 0.0521 0.0521
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0157 0.0129 0.0088
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.025 0.045 0.0411
Schistosoma mansoni tyrosine kinase 0.038 0.0898 0.0884
Echinococcus granulosus neurogenic locus notch protein 0.0305 0.064 0.064
Brugia malayi hypothetical protein 0.0225 0.0363 0.0349
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0398 0.0961 0.0947
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0278 0.0546 0.0508
Echinococcus multilocularis protein jagged 1 0.0305 0.064 0.064
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0314 0.0672 0.0532
Onchocerca volvulus Putative cubilin 0.0305 0.064 0.251
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Brugia malayi map kinase activated protein kinase protein 2 0.0792 0.2319 0.2307
Plasmodium falciparum glycogen synthase kinase 3 0.0258 0.0478 0.0439
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0165 0.0156 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0173 0.0157
Loa Loa (eye worm) hypothetical protein 0.0164 0.0153 0.0138
Echinococcus multilocularis raf serine:threonine protein kinase 0.015 0.0105 0.0105
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0168 0.0166 0.0126
Giardia lamblia Kinase, CK1 Casein kinase 0.0218 0.0339 0.0601
Echinococcus granulosus peroxidasin 0.0315 0.0674 0.0674
Onchocerca volvulus 0.0305 0.064 0.251
Plasmodium falciparum protein serine/threonine kinase-1 0.0308 0.0651 0.0613
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Entamoeba histolytica protein kinase, putative 0.0571 0.156 0.8772
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0151 0.0108 0.0093
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0231 0.0384 0.0384
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0258 0.0478 0.0439
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0151 0.0108 0.0108
Plasmodium falciparum casein kinase 2, alpha subunit 0.02 0.028 0.024
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0151 0.0135
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0435 0.109 0.1076
Trichomonas vaginalis CAMK family protein kinase 0.0542 0.146 0.4512
Onchocerca volvulus 0.0563 0.1531 0.6147
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0521 0.0506
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0202 0.0285 0.0285
Onchocerca volvulus 0.0563 0.1531 0.6147
Echinococcus granulosus notch 0.0305 0.064 0.064
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0258 0.0478 0.0463
Brugia malayi Disorganized muscle protein 1 0.0144 0.0084 0.0069
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0328 0.0288
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi hypothetical protein 0.0132 0.0045 0.003
Schistosoma mansoni hypothetical protein 0.0144 0.0084 0.0068
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0278 0.0546 0.0546
Echinococcus granulosus CDC7 cell division cycle 7 0.018 0.0208 0.0208
Echinococcus granulosus tyrosine kinase 0.0132 0.0045 0.0045
Trichomonas vaginalis STE family protein kinase 0.0172 0.0182 0.0475
Loa Loa (eye worm) hypothetical protein 0.0563 0.1531 0.1518
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0993 0.3013 0.3013
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0279 0.0549 0.0511
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0236 0.0403 0.0403
Schistosoma mansoni hypothetical protein 0.0305 0.064 0.0626
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0314 0.0672 0.0672
Trichomonas vaginalis CMGC family protein kinase 0.0258 0.0478 0.141
Schistosoma mansoni nephrin 0.0728 0.2101 0.2089
Trichomonas vaginalis STE family protein kinase 0.0273 0.053 0.1573
Schistosoma mansoni roundabout 0.0314 0.0672 0.0657
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0168 0.0166 0.0126
Entamoeba histolytica protein kinase, putative 0.0202 0.0285 0.1453
Schistosoma mansoni hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Cam kinase protein 1 0.0202 0.0285 0.0271
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0209 0.031 0.031
Echinococcus multilocularis cyclin dependent kinase 1 0.0238 0.0409 0.0409
Trypanosoma cruzi polo-like protein kinase, putative 0.0542 0.146 0.1425
Brugia malayi Calcium binding EGF domain containing protein 0.0305 0.064 0.0627
Brugia malayi p70 ribosomal S6 kinase beta 0.0571 0.156 0.1547
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0273 0.053 0.0491
Loa Loa (eye worm) hypothetical protein 0.0585 0.1606 0.1593
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0238 0.0409 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0702 0.0688
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0278 0.0546 0.0532
Loa Loa (eye worm) casein kinase 0.0362 0.0838 0.0824
Loa Loa (eye worm) hypothetical protein 0.0225 0.0363 0.0348
Echinococcus granulosus rho-associated protein kinase 1 0.0653 0.184 0.184
Echinococcus granulosus contactin 0.0333 0.0735 0.0735
Brugia malayi Muscle positioning protein 4 0.0305 0.064 0.0627
Leishmania major carbonic anhydrase-like protein 0.0214 0.0328 0.0288
Loa Loa (eye worm) hypothetical protein 0.0363 0.0841 0.0826
Loa Loa (eye worm) hypothetical protein 0.0218 0.0339 0.0324
Echinococcus granulosus protein jagged 1 0.0305 0.064 0.064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0179 0.0164
Echinococcus multilocularis c4b binding protein beta chain 0.0563 0.1531 0.1531
Echinococcus multilocularis titin 0.0144 0.0084 0.0084
Entamoeba histolytica protein kinase, putative 0.0185 0.0225 0.1109
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0333 0.0735 0.0721
Schistosoma mansoni protein kinase 0.0129 0.0032 0.0016
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0319 0.0689 0.0651
Echinococcus multilocularis mitogen activated protein kinase 14 0.0319 0.0689 0.0689
Schistosoma mansoni cell adhesion molecule 0.0144 0.0084 0.0068
Echinococcus multilocularis casein kinase I delta 0.0218 0.0339 0.0339
Schistosoma mansoni protein kinase 0.0387 0.0922 0.0908
Trichomonas vaginalis CMGC family protein kinase 0.0238 0.0409 0.1193
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0708 0.203 0.203
Giardia lamblia Kinase, STE STE20 0.0172 0.0182 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0166 0.0151
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0563 0.1531 0.1518
Entamoeba histolytica protein kinase, putative 0.0587 0.1612 0.9074
Loa Loa (eye worm) hypothetical protein 0.0243 0.0425 0.041
Echinococcus granulosus roundabout 2 0.0899 0.2689 0.2689
Brugia malayi serine/threonine-protein kinase 6 0.0236 0.0403 0.0389
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Brugia malayi Immunoglobulin I-set domain containing protein 0.0162 0.0147 0.0132
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1046 0.3196 0.3169
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0472 0.1215 0.1215
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1046 0.3196 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.019 0.0242 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1285 0.1272
Echinococcus multilocularis tyrosine protein kinase HCK 0.0185 0.0225 0.0225
Trypanosoma brucei trypanothione reductase 0.3019 1 1
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0161 0.0144 0.0144
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0708 0.203 0.2018
Schistosoma mansoni serine/threonine-protein kinase 0.0329 0.0724 0.071
Loa Loa (eye worm) TK/EGFR protein kinase 0.0701 0.2008 0.1995
Leishmania major casein kinase, putative 0.0218 0.0339 0.03
Echinococcus multilocularis titin 0.0144 0.0084 0.0084
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0302 0.0631 0.0617
Brugia malayi EGF-like domain containing protein 0.0305 0.064 0.0627
Loa Loa (eye worm) hypothetical protein 0.0314 0.0672 0.0657
Loa Loa (eye worm) hypothetical protein 0.0157 0.0129 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.1215 0.1201
Onchocerca volvulus 0.0628 0.1753 0.7055
Brugia malayi STE20-like kinase MST 0.0515 0.1366 0.1354
Echinococcus granulosus neuroglian 0.071 0.2038 0.2038
Echinococcus multilocularis glutamate synthase 0.0278 0.0546 0.0546
Echinococcus granulosus c-Jun N-terminal kinases 0.053 0.1418 0.1418
Schistosoma mansoni protein kinase 0.0871 0.2594 0.2582
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0278 0.0546 0.0531
Echinococcus granulosus roundabout 2 0.0333 0.0735 0.0735
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0144 0.0084 0.0068
Echinococcus granulosus tyrosine protein kinase Fyn 0.0308 0.0652 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0188 0.0238 0.0222
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0492 0.1285 0.1272
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0403 0.1172
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0433 0.1083 0.1083
Schistosoma mansoni septate junction protein 0.0314 0.0672 0.0657
Echinococcus granulosus Immunoglobulin 0.0171 0.0177 0.0177
Brugia malayi serine/threonine kinase 12 0.0236 0.0403 0.0389
Brugia malayi Calcium binding EGF domain containing protein 0.0305 0.064 0.0627
Echinococcus multilocularis NCK adaptor protein 0.0126 0.0023 0.0023
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0225 0.0363 0.0363
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0542 0.146 0.1446
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0308 0.0652 0.0652
Leishmania major NADH dehydrogenase, putative 0.0278 0.0546 0.0508
Loa Loa (eye worm) hypothetical protein 0.0567 0.1543 0.1529
Entamoeba histolytica hypothetical protein 0.0245 0.0433 0.2305
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0169 0.0173 0.0173
Loa Loa (eye worm) gastrulation defective protein 1 0.0794 0.2328 0.2316
Echinococcus multilocularis roundabout 2 0.0333 0.0735 0.0735
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0144 0.0085 0.0085
Brugia malayi pregnancy-associated plasma protein-A 0.0563 0.1531 0.1519
Brugia malayi Protein kinase domain containing protein 0.0645 0.1814 0.1802
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0218 0.0339 0.0324
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0251 0.0455 0.0455
Trichomonas vaginalis AGC family protein kinase 0.0273 0.053 0.1573
Schistosoma mansoni tyrosine kinase 0.0489 0.1274 0.126
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0624 0.1742 0.1742
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0278 0.0546 0.0508
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0171 0.0178 0.0163
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0171 0.0177 0.0161
Brugia malayi hypothetical protein 0.0585 0.1606 0.1594
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1046 0.3196 0.3169
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0225 0.0363 0.0324
Brugia malayi Immunoglobulin I-set domain containing protein 0.0585 0.1606 0.1594
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0521 0.0506
Schistosoma mansoni hypothetical protein 0.0171 0.0177 0.0161
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.086 0.2554 0.2542
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0308 0.0652 0.0652
Brugia malayi Protein kinase domain containing protein 0.0606 0.1679 0.1667
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0238 0.0409 0.037
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0202 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Schistosoma mansoni protein kinase 0.0736 0.2128 0.2116
Trypanosoma cruzi casein kinase, putative 0.0218 0.0339 0.03
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3019 1 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0446 0.1126 0.1126
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0166 0.0162 0.0146
Loa Loa (eye worm) hypothetical protein 0.0179 0.0207 0.0192
Entamoeba histolytica protein kinase, putative 0.0163 0.0151 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0129 0.0113
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0132 0.0045 0.0075
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0236 0.0403 0.213
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0238 0.0409 0.0409
Brugia malayi Immunoglobulin I-set domain containing protein 0.0333 0.0735 0.0722
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0328 0.0721 0.0706
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0226 0.0369 0.033
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.0433 0.2305
Onchocerca volvulus 0.0563 0.1531 0.6147
Giardia lamblia Aurora kinase 0.0236 0.0403 0.081
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0225 0.0363 0.0324
Schistosoma mansoni slit 0.0144 0.0085 0.007
Echinococcus granulosus growth factor receptor bound protein 2 0.0126 0.0023 0.0023
Echinococcus granulosus dual specificity 0.0279 0.0549 0.0549
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0226 0.0369 0.0225
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0521 0.0506
Brugia malayi Immunoglobulin domain containing protein 0.0171 0.0177 0.0162
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0144 0.0084 0.0068
Entamoeba histolytica PH domain containing protein kinase, putative 0.0329 0.0724 0.3976
Echinococcus multilocularis fat cadherin tumor suppressor 0.0305 0.0641 0.0641
Echinococcus granulosus cGMP dependent protein kinase 1 0.0169 0.0173 0.0173
Onchocerca volvulus 0.0144 0.0085 0.0243
Echinococcus granulosus serine/threonine protein kinase 0.0329 0.0724 0.0724
Schistosoma mansoni notch 0.0305 0.064 0.0626
Trichomonas vaginalis CMGC family protein kinase 0.0238 0.0409 0.1193
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0278 0.0546 0.2953
Echinococcus multilocularis serine:threonine protein kinase N2 0.0323 0.0702 0.0702
Echinococcus granulosus epidermal growth factor receptor 0.0489 0.1274 0.1274
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0308 0.0652 0.0652
Brugia malayi Sex muscle abnormal protein 5 0.0124 0.0016 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0129 0.0113
Loa Loa (eye worm) SRC-1 0.0308 0.0652 0.0637
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0308 0.0651 0.0613
Trypanosoma cruzi cdc2-related kinase 3 0.0238 0.0409 0.037
Plasmodium falciparum calcium-dependent protein kinase 5 0.0202 0.0285 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0584 0.1601 0.1588
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0169 0.0173 0.0173
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0172 0.0182 0.0182
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0768 0.2239 0.2227
Loa Loa (eye worm) hypothetical protein 0.0261 0.0487 0.0472
Schistosoma mansoni notch 0.0305 0.064 0.0626
Brugia malayi Protein kinase domain containing protein 0.0132 0.0045 0.003
Brugia malayi Protein kinase domain containing protein 0.0132 0.0045 0.003
Echinococcus granulosus c4b binding protein beta chain 0.0563 0.1531 0.1531
Giardia lamblia Kinase, CMGC SRPK 0.0166 0.0162 0.0018
Loa Loa (eye worm) hypothetical protein 0.0466 0.1196 0.1182
Giardia lamblia Kinase, NEK 0.0273 0.053 0.1228
Loa Loa (eye worm) hypothetical protein 0.0225 0.0363 0.0348
Loa Loa (eye worm) glutathione reductase 0.3019 1 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0437 0.1094 0.108
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0406 0.0991 0.0991
Echinococcus multilocularis protein tyrosine kinase 0.0583 0.16 0.16
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0171 0.0177 0.0177
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0144 0.0084 0.0084
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Onchocerca volvulus Peroxidasin homolog 0.0144 0.0085 0.0243
Schistosoma mansoni serine/threonine protein kinase 0.0512 0.1354 0.134
Echinococcus multilocularis activin receptor type 0.0131 0.0041 0.0041
Plasmodium falciparum glutathione reductase 0.1046 0.3196 0.3169
Brugia malayi Immunoglobulin I-set domain containing protein 0.0229 0.0377 0.0363
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0132 0.0044 0.0072
Echinococcus multilocularis tyrosine protein kinase 0.0311 0.066 0.066
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Echinococcus multilocularis fibropellin Ia 0.0305 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0333 0.0735 0.0721
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0993 0.3013 0.3013
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0278 0.0546 0.0546
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0144 0.0084 0.0084
Loa Loa (eye worm) protein kinase domain-containing protein 0.0428 0.1064 0.105
Onchocerca volvulus Tyrosine kinase homolog 0.0837 0.2475 1
Echinococcus multilocularis down syndrome cell adhesion 0.0144 0.0084 0.0084
Brugia malayi Protein kinase domain containing protein 0.0308 0.0651 0.0637
Giardia lamblia Kinase, CMGC MAPK 0.0168 0.0166 0.0033
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1046 0.3196 0.3169
Schistosoma mansoni tyrosine kinase 0.0423 0.1047 0.1033
Brugia malayi Doublecortin family protein 0.0302 0.0631 0.0618
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1046 0.3196 1
Trichomonas vaginalis CMGC family protein kinase 0.0258 0.0478 0.141
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0403 0.1172
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0151 0.0108 0.0108
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0189 0.024 0.0225
Echinococcus granulosus protein kinase C gamma type 0.0405 0.0986 0.0986
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0169 0.0173 0.0133
Schistosoma mansoni protein kinase 0.0236 0.0403 0.0388
Brugia malayi Variant SH3 domain containing protein 0.0124 0.0016 0.0001
Echinococcus multilocularis death associated protein kinase 1 0.0899 0.269 0.269
Echinococcus multilocularis rho associated protein kinase 0.0653 0.184 0.184
Schistosoma mansoni serine/threonine protein kinase 0.0323 0.0702 0.0688
Brugia malayi kettin 0.0144 0.0084 0.0069
Schistosoma mansoni ephrin receptor 0.0194 0.0259 0.0243
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.029 0.0589 0.0589
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0225 0.0363 0.0324
Echinococcus multilocularis CDC7 cell division cycle 7 0.018 0.0208 0.0208
Schistosoma mansoni ste20-related kinase 0.0412 0.1008 0.0994
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0446 0.1126 0.1112
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0278 0.0546 0.0508
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0736 0.2128 0.2128
Echinococcus granulosus tyrosine protein kinase 0.0311 0.066 0.066
Echinococcus multilocularis serine:threonine protein kinase 0.0229 0.0377 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0958 0.2892 0.2881
Brugia malayi Immunoglobulin domain containing protein 0.0171 0.0177 0.0162
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0202 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0371 0.0869 0.0854
Schistosoma mansoni cell adhesion molecule 0.0162 0.0147 0.0131
Brugia malayi notch-like transmembrane receptor 0.0305 0.064 0.0627
Echinococcus granulosus delta-like protein 1 0.0305 0.064 0.064
Entamoeba histolytica disulphide oxidoreductase, putative 0.0278 0.0546 0.2953
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1046 0.3196 0.3095
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0308 0.0652 0.0652
Trypanosoma cruzi casein kinase, putative 0.0218 0.0339 0.03
Echinococcus multilocularis Immunoglobulin 0.0171 0.0177 0.0177
Onchocerca volvulus Slit protein homolog 0.035 0.0795 0.314
Echinococcus granulosus dual specificity 0.0279 0.0549 0.0549
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0236 0.0403 0.213
Schistosoma mansoni serine/threonine protein kinase 0.0433 0.1083 0.1069
Onchocerca volvulus 0.0132 0.0045 0.0078
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0308 0.0651 0.0613
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0189 0.024 0.024
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0278 0.0546 0.0508
Echinococcus granulosus tyrosine protein kinase Lyn 0.0374 0.0878 0.0878
Echinococcus multilocularis casein kinase I alpha 0.0218 0.0339 0.0339
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.029 0.0589 0.0589
Loa Loa (eye worm) AGC/PKN protein kinase 0.0584 0.1601 0.1588
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0333 0.0735 0.0735
Loa Loa (eye worm) hypothetical protein 0.0881 0.2626 0.2614
Loa Loa (eye worm) hypothetical protein 0.0279 0.0551 0.0536
Schistosoma mansoni nephrin related 0.0171 0.0177 0.0161
Onchocerca volvulus 0.0305 0.064 0.251
Schistosoma mansoni tyrosine kinase 0.0423 0.1047 0.1033
Entamoeba histolytica protein kinase, putative 0.0172 0.0182 0.0863
Echinococcus multilocularis mitogen activated protein kinase 14 0.0319 0.0689 0.0689
Loa Loa (eye worm) TK/ROR protein kinase 0.0209 0.031 0.0294
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0226 0.0369 0.033
Trypanosoma brucei rac serine-threonine kinase, putative 0.0587 0.1612 0.1578
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0442 0.1115 0.1115
Loa Loa (eye worm) one IG domain family member 0.0144 0.0084 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0672 0.0658
Trypanosoma cruzi NADH dehydrogenase, putative 0.0278 0.0546 0.0508
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1046 0.3196 0.3169
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0218 0.0339 0.0324
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0166 0.0162 0.0122
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0403 0.1172
Echinococcus multilocularis protein jagged 1 0.0305 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0567 0.1543 0.1529
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0308 0.0652 0.0652
Echinococcus multilocularis tyrosine protein kinase Srms 0.0251 0.0455 0.0455
Echinococcus granulosus down syndrome cell adhesion 0.0144 0.0084 0.0084
Schistosoma mansoni tyrosine kinase 0.0606 0.1679 0.1666
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0278 0.0546 0.0508
Entamoeba histolytica protein kinase, putative 0.0144 0.0084 0.0302
Giardia lamblia Kinase, NEK 0.0273 0.053 0.1228
Echinococcus multilocularis dual specificity 0.0245 0.0433 0.0433
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0672 0.0658
Echinococcus granulosus casein kinase I delta 0.0218 0.0339 0.0339
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0278 0.0546 0.1625
Echinococcus multilocularis titin 0.0227 0.0373 0.0373
Echinococcus granulosus Immunoglobulin subtype 0.0171 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Echinococcus granulosus protein kinase 0.0307 0.0647 0.0647
Onchocerca volvulus 0.0144 0.0084 0.0236
Echinococcus multilocularis mitogen activated protein kinase 0.0168 0.0166 0.0166
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0144 0.0084 0.0068
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0169 0.0173 0.0133
Echinococcus granulosus C type lectin domian containing protein 0.0563 0.1531 0.1531
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0171 0.0177 0.0161
Loa Loa (eye worm) programmed cell death 8 0.0278 0.0546 0.0531
Onchocerca volvulus 0.0132 0.0045 0.0078
Entamoeba histolytica serine/threonine protein kinase, putative 0.0157 0.0129 0.0557
Brugia malayi hypothetical protein 0.0563 0.1531 0.1519
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0403 0.0977 0.0977
Schistosoma mansoni growth factor receptor-bound protein 0.0126 0.0023 0.0007
Plasmodium falciparum apical sushi protein 0.0563 0.1531 0.1496
Echinococcus multilocularis Immunoglobulin 0.0567 0.1543 0.1543
Loa Loa (eye worm) hypothetical protein 0.0278 0.0546 0.0531
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0871 0.2594 0.2594
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0169 0.0173 0.0133
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1046 0.3196 0.3169
Loa Loa (eye worm) hypothetical protein 0.0173 0.0184 0.0168
Echinococcus granulosus nervana 2 0.0249 0.0446 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0129 0.0113
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0278 0.0546 0.0508
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Schistosoma mansoni hypothetical protein 0.0171 0.0177 0.0161
Echinococcus multilocularis Glutaredoxin protein 5 0.0249 0.0446 0.0446
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0238 0.0409 0.0394
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Giardia lamblia Kinase, AGC AKT 0.0235 0.0397 0.0793
Echinococcus granulosus cyclin 0.0625 0.1743 0.1743
Schistosoma mansoni sulfide quinone reductase 0.0278 0.0546 0.0531
Leishmania major protein kinase A catalytic subunit 0.0226 0.0369 0.033
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0323 0.0702 0.0702
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0168 0.0166 0.0126
Echinococcus granulosus tyrosine protein kinase Fyn 0.0308 0.0652 0.0652
Schistosoma mansoni hypothetical protein 0.0144 0.0084 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0344 0.0774 0.2347
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0446 0.1126 0.1126
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0238 0.0409 0.0394
Loa Loa (eye worm) hypothetical protein 0.0239 0.0413 0.0398
Echinococcus granulosus carbonic anhydrase II 0.0214 0.0328 0.0328
Leishmania major protein kinase A catalytic subunit isoform 2 0.0226 0.0369 0.033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0162 0.0147 0.0131
Brugia malayi SRC-1 0.0308 0.0652 0.0638
Loa Loa (eye worm) hypothetical protein 0.0314 0.0672 0.0657
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0273 0.053 0.0388
Loa Loa (eye worm) hypothetical protein 0.0305 0.064 0.0626
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1046 0.3196 0.3186
Brugia malayi Immunoglobulin I-set domain containing protein 0.051 0.1347 0.1334
Echinococcus granulosus casein kinase I alpha 0.0218 0.0339 0.0339
Brugia malayi Variant SH3 domain containing protein 0.0151 0.0108 0.0094
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1046 0.3196 0.2803
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Giardia lamblia Kinase, CMGC DYRK 0.0279 0.0549 0.1292
Echinococcus multilocularis casein kinase I delta 0.0218 0.0339 0.0339
Echinococcus granulosus epidermal growth factor receptor 0.0701 0.2008 0.2008
Echinococcus multilocularis neuroglian 0.071 0.2038 0.2038
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0369 0.0354
Giardia lamblia Kinase, CMGC GSK 0.0258 0.0478 0.1057
Loa Loa (eye worm) hypothetical protein 0.0213 0.0323 0.0307
Entamoeba histolytica protein kinase, putative 0.0258 0.0478 0.2561
Echinococcus multilocularis hemicentin 1 0.0314 0.0672 0.0672
Giardia lamblia Kinase, PLK 0.0542 0.146 0.4287
Trypanosoma brucei SNF1-related protein kinases, putative 0.0157 0.0129 0.0088
Loa Loa (eye worm) hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Protein kinase domain containing protein 0.0389 0.0929 0.0916
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0571 0.156 0.1546
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0238 0.0409 0.037
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Brugia malayi casein kinase I 0.0218 0.0339 0.0325
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0258 0.0478 0.0478
Echinococcus granulosus tyrosine kinase 0.0251 0.0455 0.0455
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Echinococcus granulosus thioredoxin glutathione reductase 0.3019 1 1
Brugia malayi Protein kinase domain containing protein 0.0736 0.2128 0.2117
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0366 0.0852 0.0852
Echinococcus multilocularis hypothetical protein 0.0205 0.0295 0.0295
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0308 0.0652 0.0652
Onchocerca volvulus 0.0218 0.0339 0.128
Onchocerca volvulus 0.0563 0.1531 0.6147
Loa Loa (eye worm) hypothetical protein 0.0314 0.0672 0.0657
Echinococcus granulosus protein kinase c epsilon type 0.041 0.1001 0.1001
Brugia malayi Temporarily assigned gene name protein 59 0.0259 0.0483 0.0469
Echinococcus granulosus neurogenic locus notch protein 0.0305 0.064 0.064
Trypanosoma cruzi trypanothione reductase, putative 0.1046 0.3196 0.3169
Schistosoma mansoni hypothetical protein 0.0171 0.0177 0.0161
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0279 0.0549 0.0535
Echinococcus multilocularis Immunoglobulin 0.0567 0.1543 0.1543
Echinococcus multilocularis protein kinase shaggy 0.0258 0.0478 0.0478
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.029 0.059 0.059
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0515 0.1366 0.1353
Brugia malayi Protein kinase domain containing protein 0.0311 0.066 0.0647
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0329 0.0723 0.0723
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0723 0.0709
Trichomonas vaginalis CMGC family protein kinase 0.02 0.028 0.0784
Onchocerca volvulus 0.0162 0.0147 0.0495
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1046 0.3196 0.3169
Trichomonas vaginalis glutamate synthase, putative 0.0278 0.0546 0.1625
Brugia malayi Immunoglobulin I-set domain containing protein 0.0314 0.0672 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.1126 0.1112
Trichomonas vaginalis AGC family protein kinase 0.0587 0.1612 0.4994
Echinococcus multilocularis protein jagged 2 0.0305 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0279 0.0551 0.0536
Brugia malayi putative serine/threonine kinase SADA gamma 0.0157 0.0129 0.0114
Trypanosoma brucei cdc2-related kinase 1 0.0238 0.0409 0.037
Onchocerca volvulus 0.0563 0.1531 0.6147
Schistosoma mansoni laminin gamma-3 chain 0.0305 0.064 0.0626
Brugia malayi serine/threonine-protein kinase PAK 7 0.0466 0.1195 0.1182
Echinococcus granulosus expressed protein 0.0166 0.0162 0.0162
Loa Loa (eye worm) thyroid receptor interactor 0.0206 0.0298 0.0283
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0171 0.0178 0.0463
Onchocerca volvulus 0.0653 0.184 0.7408
Loa Loa (eye worm) LAD-2 short isoform 0.0171 0.0177 0.0161
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0323 0.0702 0.0702
Echinococcus multilocularis 0.0307 0.0647 0.0647
Leishmania major protein kinase, putative 0.0308 0.0651 0.0613
Echinococcus multilocularis serine threonine protein kinase 0.0405 0.0986 0.0986
Trypanosoma cruzi cdc2-related kinase 1 0.0238 0.0409 0.037
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Schistosoma mansoni titin 0.0144 0.0084 0.0068
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0307 0.0647 0.0633
Loa Loa (eye worm) hypothetical protein 0.0144 0.0084 0.0068
Brugia malayi Cyclin, N-terminal domain containing protein 0.0625 0.1743 0.173
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0258 0.0478 0.0439
Brugia malayi Immunoglobulin I-set domain containing protein 0.0144 0.0084 0.0069
Loa Loa (eye worm) AUR protein kinase 0.0236 0.0403 0.0388
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0387 0.0922 0.0908
Toxoplasma gondii aurora kinase 0.0236 0.0403 0.0364
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0214 0.0328 0.0312
Loa Loa (eye worm) animal heme peroxidase 0.0144 0.0084 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0168 0.0166 0.0425
Echinococcus granulosus mitogen activated protein kinase 0.0168 0.0166 0.0166
Echinococcus granulosus hypothetical protein 0.0243 0.0425 0.0425
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0045 0.0029
Echinococcus multilocularis cyclin dependent kinase 19 0.086 0.2554 0.2554
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0369 0.0354
Echinococcus granulosus dual specificity protein kinase clk2 0.0308 0.0651 0.0651
Onchocerca volvulus 0.0587 0.1614 0.6486
Echinococcus granulosus protein kinase shaggy 0.0258 0.0478 0.0478
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0162 0.0147 0.0131
Trypanosoma cruzi cdc2-related kinase 3 0.0238 0.0409 0.037
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0226 0.0369 0.0369
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1046 0.3196 0.3196
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.02 0.028 0.0134
Loa Loa (eye worm) hypothetical protein 0.0162 0.0147 0.0131
Giardia lamblia Kinase, CDC7 0.018 0.0208 0.017
Trypanosoma brucei cdc2-related kinase 3 0.0238 0.0409 0.037
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0255 0.0469 0.0453
Echinococcus granulosus raf serine:threonine protein kinase 0.015 0.0105 0.0105
Onchocerca volvulus 0.0144 0.0084 0.0236
Toxoplasma gondii EGF family domain-containing protein 0.0305 0.064 0.0602
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0152 0.0113 0.0073
Echinococcus granulosus NDR protein kinase 0.0323 0.0702 0.0702
Onchocerca volvulus 0.0371 0.0869 0.3442
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0129 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0403 0.0978 0.0963
Trichomonas vaginalis CAMK family protein kinase 0.0542 0.146 0.4512
Loa Loa (eye worm) AGC/PKG protein kinase 0.0169 0.0173 0.0157
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1046 0.3196 0.2803
Schistosoma mansoni cell polarity protein 0.0305 0.064 0.0626
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0278 0.0546 0.0546
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0171 0.0177 0.0177
Entamoeba histolytica PH domain containing protein kinase, putative 0.0329 0.0724 0.3976

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 124 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 124 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 124 nM Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay ChEMBL. 22370338
Ki (binding) = 175 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 175 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 175 nM Inhibition of human carbonic anhydrase 9 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assay ChEMBL. 22370338
Ki (binding) = 2950 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455
Ki (binding) = 2950 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455
Ki (binding) = 2950 nM Inhibition of human cloned carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay ChEMBL. 22370338

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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