Detailed information for compound 312698

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 295.293 | Formula: C16H13N3O3
  • H donors: 2 H acceptors: 4 LogP: 1.74 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=c1n(C)c(C(=O)Nc2ccccn2)c(c2c1cccc2)O
  • InChi: 1S/C16H13N3O3/c1-19-13(15(21)18-12-8-4-5-9-17-12)14(20)10-6-2-3-7-11(10)16(19)22/h2-9,20H,1H3,(H,17,18,21)
  • InChiKey: VQEAXBSFTRDXPB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi NADH dehydrogenase, putative 0.0069 0.0822 0.0728
Onchocerca volvulus 0.0028 0.0273 0.1373
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0069 0.0822 0.0791
Plasmodium vivax thioredoxin reductase, putative 0.0751 1 1
Schistosoma mansoni hypothetical protein 0.0036 0.0379 0.0346
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0036 0.0379 0.0346
Echinococcus multilocularis neurogenic locus notch protein 4 0.0076 0.0914 0.0883
Onchocerca volvulus 0.0076 0.0914 0.5043
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Schistosoma mansoni notch 0.0076 0.0914 0.0883
Brugia malayi intracellular kinase 0.0043 0.0475 0.0443
Echinococcus multilocularis cyclin 0.0202 0.2611 0.2586
Schistosoma mansoni fras1 related extracellular matrix protein 0.0016 0.0104 0.007
Loa Loa (eye worm) hypothetical protein 0.0111 0.1384 0.1355
Schistosoma mansoni sulfide quinone reductase 0.0069 0.0822 0.0791
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0069 0.0822 0.2854
Echinococcus multilocularis neuroglian 0.0064 0.076 0.0728
Echinococcus granulosus protein jagged 1 0.0076 0.0914 0.0883
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0011 0.0045 0.0011
Echinococcus granulosus protein jagged 2 0.0076 0.0914 0.0883
Echinococcus multilocularis titin 0.0028 0.0273 0.024
Schistosoma mansoni netrin receptor unc5 0.0036 0.0379 0.0346
Echinococcus multilocularis down syndrome cell adhesion 0.0028 0.0273 0.024
Echinococcus granulosus histone lysine methyltransferase setb 0.0011 0.0045 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0379 0.0346
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.187 0.1843
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0066 0.0778 0.0746
Schistosoma mansoni tyrosine kinase 0.0064 0.076 0.0728
Echinococcus granulosus lachesin 0.0064 0.076 0.0728
Echinococcus granulosus protein kinase shaggy 0.0043 0.0475 0.0443
Brugia malayi Immunoglobulin domain containing protein 0.0036 0.0379 0.0346
Leishmania major cathepsin L-like protease 0.0024 0.0218 0.0218
Onchocerca volvulus Tyrosine kinase homolog 0.0028 0.0273 0.1373
Echinococcus multilocularis 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Onchocerca volvulus 0.0016 0.0104 0.0402
Schistosoma mansoni glutamate synthase 0.0069 0.0822 0.0791
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Schistosoma mansoni lipoxygenase 0.0088 0.1076 0.1045
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0069 0.0822 0.0822
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Echinococcus multilocularis protein jagged 1 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Trichomonas vaginalis bromodomain-containing protein, putative 0.0016 0.011 0.0024
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) doublecortin family protein 0.0015 0.009 0.0056
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0069 0.0822 0.0791
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.026 0.3395 0.3335
Brugia malayi Doublecortin family protein 0.0015 0.009 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Onchocerca volvulus 0.0028 0.0273 0.1373
Echinococcus multilocularis neurogenic locus notch protein 0.0076 0.0914 0.0883
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0055 0.0632 0.06
Echinococcus multilocularis slit 2 protein 0.0076 0.0914 0.0883
Schistosoma mansoni basigin related 0.0036 0.0379 0.0346
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.026 0.3395 0.3372
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0028 0.0273 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Brugia malayi Cyclin C 0.0407 0.5369 0.5353
Trichomonas vaginalis glutathione reductase, putative 0.026 0.3395 1
Echinococcus multilocularis C type lectin 0.0016 0.0104 0.007
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0036 0.0379 0.0346
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Onchocerca volvulus 0.014 0.1778 1
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0036 0.0379 0.0346
Leishmania major cathepsin L-like protease 0.0024 0.0218 0.0218
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0069 0.0822 0.2854
Schistosoma mansoni notch 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Echinococcus granulosus Glycosyl transferase family 35 0.0052 0.0588 0.0555
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Brugia malayi Peroxidasin 0.0064 0.076 0.0728
Echinococcus multilocularis Glycosyl transferase, family 35 0.0052 0.0588 0.0555
Echinococcus multilocularis titin 0.0028 0.0273 0.024
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0069 0.0822 0.0822
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Schistosoma mansoni notch 0.0076 0.0914 0.0883
Echinococcus multilocularis dna polymerase kappa 0.0016 0.0102 0.0068
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Echinococcus granulosus microtubule associated protein 2 0.0262 0.3412 0.339
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0069 0.0822 0.0791
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0028 0.0273 0.024
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0076 0.0914 0.0883
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0069 0.0822 0.2187
Onchocerca volvulus 0.0043 0.0475 0.253
Schistosoma mansoni hypothetical protein 0.0032 0.032 0.0287
Brugia malayi Thioredoxin reductase 0.0751 1 1
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0036 0.0379 0.0346
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0069 0.0822 0.2187
Onchocerca volvulus 0.0016 0.0104 0.0402
Loa Loa (eye worm) hypothetical protein 0.0147 0.187 0.1843
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0218 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.3404 0.3382
Schistosoma mansoni basigin related 0.0036 0.0379 0.0346
Echinococcus multilocularis protein kinase shaggy 0.0043 0.0475 0.0443
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Onchocerca volvulus 0.0076 0.0914 0.5043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Trichomonas vaginalis apoptosis inducing factor, putative 0.0069 0.0822 0.2187
Loa Loa (eye worm) LAD-2 short isoform 0.0036 0.0379 0.0346
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0036 0.0379 0.0346
Schistosoma mansoni neuroglian 0.0064 0.076 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0069 0.0822 0.2187
Schistosoma mansoni basigin related 0.0036 0.0379 0.0346
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Echinococcus granulosus contactin 0.0064 0.076 0.0728
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Onchocerca volvulus Slit protein homolog 0.0076 0.0914 0.5043
Schistosoma mansoni hypothetical protein 0.0036 0.0379 0.0346
Schistosoma mansoni hypothetical protein 0.0015 0.009 0.0056
Schistosoma mansoni cell adhesion molecule 0.0028 0.0273 0.024
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0016 0.011 0.0065
Echinococcus granulosus titin 0.0028 0.0273 0.024
Brugia malayi Prion-like- 0.0028 0.0273 0.024
Giardia lamblia Glutamate synthase 0.0069 0.0822 0.2422
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0011 0.0045 0.0011
Trichomonas vaginalis glutamate synthase, putative 0.0069 0.0822 0.2187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Echinococcus multilocularis Immunoglobulin 0.0111 0.1384 0.1355
Trypanosoma brucei protein kinase, putative 0.0043 0.0475 0.0475
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0069 0.0822 0.2187
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0025 0.0229 0.0196
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0111 0.1384 0.1355
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0025 0.0229 0.0196
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Echinococcus multilocularis RUN 0.0015 0.009 0.0056
Onchocerca volvulus 0.0016 0.0104 0.0402
Onchocerca volvulus 0.0015 0.009 0.0323
Schistosoma mansoni polycystin 1-related 0.0015 0.009 0.0056
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.026 0.3395 1
Trypanosoma cruzi trypanothione reductase, putative 0.0751 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0069 0.0822 0.0822
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0069 0.0822 0.0822
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0069 0.0822 0.2187
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0069 0.0822 0.0822
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0751 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Onchocerca volvulus 0.0076 0.0914 0.5043
Mycobacterium ulcerans monoxygenase 0.0069 0.0822 0.2187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Onchocerca volvulus Glycogen phosphorylase homolog 0.0052 0.0588 0.3174
Toxoplasma gondii thioredoxin reductase 0.0751 1 1
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0069 0.0822 0.0791
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0379 0.0346
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0025 0.0229 0.0196
Entamoeba histolytica hypothetical protein 0.0032 0.032 0.089
Entamoeba histolytica glycogen phosphorylase, putative 0.0022 0.0193 0.0396
Toxoplasma gondii rhoptry neck protein RON9 0.014 0.1778 0.1741
Brugia malayi Immunoglobulin domain containing protein 0.0036 0.0379 0.0346
Echinococcus granulosus titin 0.003 0.0291 0.0258
Echinococcus multilocularis cyclin dependent kinase 19 0.0261 0.3404 0.3382
Brugia malayi hypothetical protein 0.0111 0.1384 0.1355
Schistosoma mansoni cell adhesion molecule 0.0036 0.0379 0.0346
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0015 0.009 0.0056
Schistosoma mansoni hypothetical protein 0.0036 0.0379 0.0346
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.014 0.1778 0.175
Onchocerca volvulus 0.0028 0.0273 0.1373
Loa Loa (eye worm) Notch2 0.0076 0.0914 0.0883
Plasmodium falciparum thioredoxin reductase 0.0751 1 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0069 0.0822 0.0822
Loa Loa (eye worm) notch protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Brugia malayi Myb-like DNA-binding domain containing protein 0.0028 0.0273 0.024
Schistosoma mansoni hypothetical protein 0.0016 0.0104 0.007
Brugia malayi Pre-SET motif family protein 0.0079 0.0954 0.0923
Schistosoma mansoni hypothetical protein 0.0036 0.0379 0.0346
Giardia lamblia Histone acetyltransferase GCN5 0.0015 0.0092 0.027
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0069 0.0822 0.0739
Plasmodium falciparum glutathione reductase 0.0751 1 1
Echinococcus multilocularis roundabout 2 0.0064 0.076 0.0728
Echinococcus granulosus neurogenic locus notch protein 4 0.0076 0.0914 0.0883
Onchocerca volvulus 0.0076 0.0914 0.5043
Mycobacterium ulcerans ferredoxin reductase 0.0069 0.0822 0.2187
Leishmania major hypothetical protein, conserved 0.0069 0.0822 0.0822
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.026 0.3395 0.3365
Brugia malayi Muscle positioning protein 4 0.0076 0.0914 0.0883
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.026 0.3395 1
Echinococcus granulosus lymphocyte antigen 75 0.0016 0.0104 0.007
Echinococcus granulosus neuroglian 0.0139 0.1765 0.1737
Onchocerca volvulus 0.0028 0.0273 0.1373
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0043 0.0475 0.0475
Schistosoma mansoni septate junction protein 0.0064 0.076 0.0728
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0069 0.0822 0.0791
Toxoplasma gondii hypothetical protein 0.0016 0.0104 0.006
Leishmania major hypothetical protein, conserved 0.0069 0.0822 0.0822
Trypanosoma cruzi NADH dehydrogenase, putative 0.0069 0.0822 0.0728
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0028 0.0273 0.024
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Echinococcus multilocularis fat cadherin tumor suppressor 0.0076 0.0914 0.0883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Plasmodium falciparum apical sushi protein 0.014 0.1778 0.1703
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0273 0.1373
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0218 0.0117
Brugia malayi Sushi domain 0.014 0.1778 0.175
Echinococcus granulosus leucine rich repeat containing protein 4 0.0028 0.0273 0.024
Schistosoma mansoni slit 0.0076 0.0914 0.0883
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0016 0.0104 0.007
Schistosoma mansoni nephrin related 0.0036 0.0379 0.0346
Schistosoma mansoni titin 0.0028 0.0273 0.024
Schistosoma mansoni lipoxygenase 0.0061 0.072 0.0688
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0076 0.0914 0.0883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0588 0.1938
Echinococcus granulosus C type lectin 0.0016 0.0104 0.007
Toxoplasma gondii EGF family domain-containing protein 0.0076 0.0914 0.0873
Echinococcus multilocularis Immunoglobulin 0.0036 0.0379 0.0346
Plasmodium vivax apical sushi protein, putative 0.014 0.1778 0.1741
Echinococcus granulosus hemicentin 1 0.0064 0.076 0.0728
Echinococcus multilocularis transcription factor Dp 1 0.0014 0.0087 0.0054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Schistosoma mansoni sulfide quinone reductase 0.0069 0.0822 0.0791
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0069 0.0822 0.0791
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0261 0.3404 0.3382
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0069 0.0822 0.0822
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.032 0.0287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0379 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Schistosoma mansoni g1/s-specific cyclin C 0.0407 0.5369 0.5353
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.026 0.3395 0.3395
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0069 0.0822 0.0822
Echinococcus multilocularis C type lectin domian containing protein 0.014 0.1778 0.175
Brugia malayi hypothetical protein 0.0016 0.0104 0.007
Toxoplasma gondii selenide, water dikinase 0.0069 0.0822 0.0781
Echinococcus granulosus notch 0.0076 0.0914 0.0883
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0016 0.0104 0.007
Brugia malayi notch-like transmembrane receptor 0.0076 0.0914 0.0883
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0069 0.0822 0.2187
Onchocerca volvulus 0.0016 0.0104 0.0402
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0069 0.0822 0.0822
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Plasmodium falciparum ferrodoxin reductase-like protein 0.0069 0.0822 0.0739
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Onchocerca volvulus 0.014 0.1778 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Echinococcus granulosus neurogenic locus notch protein 0.0076 0.0914 0.0883
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0028 0.0273 0.024
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0064 0.076 0.0728
Echinococcus granulosus protein jagged 2 0.0076 0.0914 0.0883
Echinococcus multilocularis protein jagged 1 0.0076 0.0914 0.0883
Giardia lamblia Kinase, CMGC GSK 0.0043 0.0475 0.14
Onchocerca volvulus 0.0028 0.0273 0.1373
Loa Loa (eye worm) hypothetical protein 0.0175 0.2251 0.2225
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0069 0.0822 0.0791
Loa Loa (eye worm) ShTK domain-containing protein 0.0016 0.0104 0.007
Mycobacterium ulcerans NADH dehydrogenase 0.0069 0.0822 0.2187
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Brugia malayi acetyltransferase, GNAT family protein 0.0055 0.0632 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Brugia malayi Protein kinase domain containing protein 0.0261 0.3404 0.3382
Schistosoma mansoni titin 0.0028 0.0273 0.024
Brugia malayi Prion-like- 0.0028 0.0273 0.024
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.026 0.3395 0.3395
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0076 0.0914 0.5043
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0022 0.019 0.0089
Echinococcus multilocularis neuroglian 0.0139 0.1765 0.1737
Onchocerca volvulus 0.0016 0.0104 0.0402
Echinococcus granulosus down syndrome cell adhesion 0.0028 0.0273 0.024
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.026 0.3395 0.3365
Brugia malayi basement membrane proteoglycan precursor 0.0036 0.0379 0.0346
Onchocerca volvulus 0.014 0.1778 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Leishmania major hypothetical protein, conserved 0.0069 0.0822 0.0822
Brugia malayi Immunoglobulin I-set domain containing protein 0.0111 0.1384 0.1355
Plasmodium vivax multidomain scavenger receptor, putative 0.0015 0.009 0.0046
Brugia malayi Heparan sulfate 0.0036 0.0379 0.0346
Echinococcus multilocularis neurogenic locus protein delta 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Schistosoma mansoni hypothetical protein 0.0069 0.0822 0.0791
Trypanosoma brucei trypanothione reductase 0.0751 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0069 0.0822 0.0781
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0016 0.0104 0.007
Schistosoma mansoni cell adhesion molecule 0.0064 0.076 0.0728
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Echinococcus granulosus low density lipoprotein receptor ldl 0.0036 0.0379 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0069 0.0822 0.0791
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0069 0.0822 0.0822
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0069 0.0822 0.0781
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0064 0.076 0.0728
Echinococcus granulosus peroxidasin 0.0064 0.076 0.0728
Loa Loa (eye worm) hypothetical protein 0.0036 0.0379 0.0346
Leishmania major NADH dehydrogenase, putative 0.0069 0.0822 0.0822
Brugia malayi Immunoglobulin domain containing protein 0.0036 0.0379 0.0346
Echinococcus granulosus basement membrane specific heparan sulfate 0.0036 0.0379 0.0346
Brugia malayi Prion-like- 0.0028 0.0273 0.024
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.026 0.3395 1
Echinococcus granulosus glycogen phosphorylase 0.0052 0.0588 0.0555
Echinococcus multilocularis neural cadherin 0.0076 0.0914 0.0883
Schistosoma mansoni titin 0.003 0.0291 0.0258
Echinococcus multilocularis Immunoglobulin 0.0036 0.0379 0.0346
Brugia malayi hypothetical protein 0.0036 0.0379 0.0346
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0043 0.0475 0.0443
Schistosoma mansoni notch 0.0076 0.0914 0.0883
Plasmodium vivax glutathione reductase, putative 0.0751 1 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0379 0.0346
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0064 0.076 0.0728
Echinococcus multilocularis lipoxygenase domain containing protein 0.0015 0.009 0.0056
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0069 0.0822 0.0728
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0064 0.076 0.0728
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0069 0.0822 0.2854
Schistosoma mansoni hypothetical protein 0.0016 0.0104 0.007
Entamoeba histolytica glycogenphosphorylase, putative 0.0022 0.0193 0.0396
Echinococcus granulosus C type lectin domian containing protein 0.014 0.1778 0.175
Schistosoma mansoni septate junction protein 0.0076 0.0914 0.0883
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) glycogen phosphorylase 0.0052 0.0588 0.0555
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Toxoplasma gondii NADPH-glutathione reductase 0.026 0.3395 0.3365
Schistosoma mansoni cell polarity protein 0.0076 0.0914 0.0883
Schistosoma mansoni disulfide oxidoreductase 0.0069 0.0822 0.0791
Entamoeba histolytica protein kinase, putative 0.0043 0.0475 0.1499
Trypanosoma brucei unspecified product 0.0013 0.0068 0.0068
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0111 0.1384 0.1355
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3327
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Brugia malayi Animal haem peroxidase family protein 0.0028 0.0273 0.024
Entamoeba histolytica hypothetical protein 0.0032 0.032 0.089
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0036 0.0379 0.0346
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0069 0.0822 0.0728
Schistosoma mansoni titin 0.0028 0.0273 0.024
Toxoplasma gondii rhoptry neck protein RON1 0.014 0.1778 0.1741
Leishmania major trypanothione reductase 0.0751 1 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0069 0.0822 0.0739
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0043 0.0475 0.0443
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0069 0.0822 0.0791
Echinococcus multilocularis glutamate synthase 0.0069 0.0822 0.0791
Echinococcus granulosus Immunoglobulin 0.0036 0.0379 0.0346
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0036 0.0379 0.0346
Plasmodium vivax ferrodoxin reductase, putative 0.0069 0.0822 0.0781
Echinococcus granulosus neural cadherin 0.0076 0.0914 0.0883
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Onchocerca volvulus 0.014 0.1778 1
Entamoeba histolytica glycogen phosphorylase, putative 0.0022 0.0193 0.0396
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0475 0.1499
Giardia lamblia Thioredoxin reductase 0.0069 0.0822 0.2422
Schistosoma mansoni glycogen phosphorylase 0.0052 0.0588 0.0555
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0069 0.0822 0.2187
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0064 0.076 0.4161
Echinococcus multilocularis thioredoxin glutathione reductase 0.0751 1 1
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0064 0.076 0.0728
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0043 0.0475 0.0443
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0028 0.0273 0.024
Schistosoma mansoni nephrin 0.0139 0.1765 0.1737
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0069 0.0822 0.2187
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0011 0.0045 0.0011
Echinococcus granulosus dna polymerase kappa 0.0016 0.0102 0.0068
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Schistosoma mansoni cell adhesion molecule 0.0028 0.0273 0.024
Onchocerca volvulus 0.0016 0.0104 0.0402
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Onchocerca volvulus Putative titin 0.0028 0.0273 0.1373
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0069 0.0822 0.2187
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.032 0.0287
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0069 0.0822 0.0728
Echinococcus granulosus cyclin 0.0202 0.2611 0.2586
Brugia malayi carbohydrate phosphorylase 0.0052 0.0588 0.0555
Schistosoma mansoni notch 0.0076 0.0914 0.0883
Onchocerca volvulus 0.014 0.1778 1
Schistosoma mansoni rab6-interacting 0.0015 0.009 0.0056
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0036 0.0379 0.0346
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0069 0.0822 0.2187
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0069 0.0822 0.0728
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0191 0.2465 0.244
Onchocerca volvulus 0.014 0.1778 1
Onchocerca volvulus 0.0016 0.0104 0.0402
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0011 0.0045 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Trypanosoma brucei DNA polymerase IV, putative 0.0013 0.0068 0.0068
Schistosoma mansoni titin 0.0028 0.0273 0.024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Schistosoma mansoni hypothetical protein 0.0036 0.0379 0.0346
Onchocerca volvulus Peroxidasin homolog 0.0028 0.0273 0.1373
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Echinococcus multilocularis c4b binding protein beta chain 0.014 0.1778 0.175
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0202 0.2611 0.2586
Schistosoma mansoni netrin receptor unc5 0.0036 0.0379 0.0346
Onchocerca volvulus 0.014 0.1778 1
Echinococcus multilocularis roundabout 2 0.0175 0.2251 0.2225
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0025 0.0229 0.0129
Giardia lamblia High cysteine protein 0.0076 0.0914 0.2691
Schistosoma mansoni cell adhesion molecule 0.0028 0.0273 0.024
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0016 0.011 0.0024
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0069 0.0822 0.2422
Schistosoma mansoni glycogen phosphorylase 0.0022 0.0193 0.016
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0069 0.0822 0.2187
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0088 0.1076 0.1045
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0069 0.0822 0.0781
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0202 0.2611 0.2586
Onchocerca volvulus 0.0011 0.0045 0.0062
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0043 0.0475 0.0443
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0069 0.0822 0.0781
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0036 0.0379 0.0346
Brugia malayi hypothetical protein 0.0015 0.009 0.0056
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0036 0.0379 0.0346
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Onchocerca volvulus 0.0069 0.0822 0.4519
Plasmodium falciparum histone acetyltransferase GCN5 0.0015 0.0092 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0069 0.0822 0.0781
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0028 0.0273 0.024
Loa Loa (eye worm) TK protein kinase 0.0028 0.0273 0.024
Schistosoma mansoni notch 0.0076 0.0914 0.0883
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3327
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0069 0.0822 0.0791
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0069 0.0822 0.0791
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0016 0.0104 0.007
Onchocerca volvulus 0.014 0.1778 1
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0475 0.1134
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Echinococcus granulosus histone acetyltransferase KAT2B 0.0053 0.0611 0.0579
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Mycobacterium tuberculosis Probable reductase 0.0069 0.0822 0.0822
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0191 0.2465 0.244
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0036 0.0379 0.0346
Echinococcus granulosus neuroglian 0.0064 0.076 0.0728
Echinococcus multilocularis peroxidasin 0.0064 0.076 0.0728
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0069 0.0822 0.0728
Echinococcus granulosus cyclin dependent kinase 19 0.0261 0.3404 0.3382
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Onchocerca volvulus Putative cubilin 0.0076 0.0914 0.5043
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.026 0.3395 0.3395
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0036 0.0379 0.0346
Echinococcus granulosus RUN 0.0015 0.009 0.0056
Schistosoma mansoni septate junction protein 0.0036 0.0379 0.0346
Echinococcus multilocularis notch 0.0076 0.0914 0.0883
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.026 0.3395 0.3395
Loa Loa (eye worm) animal heme peroxidase 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0022 0.0193 0.0277
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Brugia malayi Delta serrate ligand family protein 0.0076 0.0914 0.0883
Schistosoma mansoni microtubule-associated protein tau 0.0262 0.3412 0.339
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0069 0.0822 0.0791
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3327
Echinococcus granulosus delta-like protein 1 0.0076 0.0914 0.0883
Schistosoma mansoni hypothetical protein 0.0016 0.0104 0.007
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0218 0.0117
Onchocerca volvulus 0.0076 0.0914 0.5043
Giardia lamblia NADH oxidase lateral transfer candidate 0.026 0.3395 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Echinococcus granulosus slit 2 protein 0.0076 0.0914 0.0883
Leishmania major dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3395
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Mycobacterium ulcerans flavoprotein disulfide reductase 0.026 0.3395 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0069 0.0822 0.0822
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0011 0.0045 0.0011
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.026 0.3395 0.3395
Brugia malayi Prion-like- 0.0064 0.076 0.0728
Loa Loa (eye worm) lectin C-type domain-containing protein 0.0016 0.0104 0.007
Echinococcus granulosus fibropellin Ia 0.0076 0.0914 0.0883
Schistosoma mansoni laminin gamma-3 chain 0.0076 0.0914 0.0883
Mycobacterium ulcerans dehydrogenase 0.0069 0.0822 0.2187
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Onchocerca volvulus 0.0028 0.0273 0.1373
Echinococcus granulosus transcription factor Dp 1 0.0014 0.0087 0.0054
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Schistosoma mansoni hypothetical protein 0.0076 0.0914 0.0883
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0036 0.0379 0.0346
Loa Loa (eye worm) hypothetical protein 0.0036 0.0379 0.0346
Leishmania major cathepsin L-like protease 0.0024 0.0218 0.0218
Schistosoma mansoni hypothetical protein 0.0036 0.0379 0.0346
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.032 0.0287
Leishmania major dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3395
Plasmodium falciparum glycogen synthase kinase 3 0.0043 0.0475 0.0388
Echinococcus granulosus glutamate synthase 0.0069 0.0822 0.0791
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.026 0.3395 0.3395
Schistosoma mansoni titin 0.0028 0.0273 0.024
Schistosoma mansoni peroxidasin 0.0036 0.0379 0.0346
Echinococcus granulosus insulin growth factor binding 0.0028 0.0273 0.024
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Brugia malayi Disorganized muscle protein 1 0.0028 0.0273 0.024
Schistosoma mansoni septate junction protein 0.0036 0.0379 0.0346
Brugia malayi hypothetical protein 0.0015 0.009 0.0056
Onchocerca volvulus 0.014 0.1778 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0016 0.011 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0291 0.0258
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0025 0.0229 0.0229
Schistosoma mansoni nephrin related 0.0028 0.0273 0.024
Echinococcus granulosus netrin receptor unc 5 0.0036 0.0379 0.0346
Echinococcus granulosus neurogenic locus protein delta 0.0076 0.0914 0.0883
Echinococcus multilocularis titin 0.0028 0.0273 0.024
Schistosoma mansoni glutamate synthase 0.0069 0.0822 0.0791
Echinococcus multilocularis microtubule associated protein 2 0.0262 0.3412 0.339
Giardia lamblia Kinase, CMGC GSK 0.0043 0.0475 0.14
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0069 0.0822 0.0791
Plasmodium falciparum glutathione reductase 0.026 0.3395 0.3335
Echinococcus multilocularis neurogenic locus notch protein 0.0076 0.0914 0.0883
Brugia malayi EGF-like domain containing protein 0.0076 0.0914 0.0883
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0036 0.0379 0.0346
Onchocerca volvulus 0.0028 0.0273 0.1373
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0069 0.0822 0.2187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0069 0.0822 0.0781
Echinococcus multilocularis roundabout 2 0.0064 0.076 0.0728
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.026 0.3395 0.3372
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0069 0.0822 0.0822
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Trypanosoma cruzi trypanothione reductase, putative 0.026 0.3395 0.3327
Trichomonas vaginalis glycogen phosphorylase, putative 0.0052 0.0588 0.1475
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Loa Loa (eye worm) one IG domain family member 0.0028 0.0273 0.024
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0069 0.0822 0.0822
Echinococcus multilocularis titin 0.003 0.0291 0.0258
Brugia malayi GCC2 and GCC3 family protein 0.0216 0.28 0.2775
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Mycobacterium ulcerans glutamate synthase subunit beta 0.0069 0.0822 0.2187
Echinococcus granulosus lipoxygenase domain containing protein 0.0015 0.009 0.0056
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0379 0.0346
Trichomonas vaginalis glycogen phosphorylase, putative 0.0052 0.0588 0.1475
Schistosoma mansoni cell adhesion molecule 0.0064 0.076 0.0728
Mycobacterium tuberculosis Probable dehydrogenase 0.0069 0.0822 0.0822
Trichomonas vaginalis mercuric reductase, putative 0.026 0.3395 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0011 0.0039 0.0005
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0064 0.076 0.0728
Onchocerca volvulus 0.0016 0.0104 0.0402
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Loa Loa (eye worm) cyclin C 0.0407 0.5369 0.5353
Loa Loa (eye worm) TK/ROR protein kinase 0.0028 0.0273 0.024
Echinococcus granulosus Immunoglobulin 0.0036 0.0379 0.0346
Schistosoma mansoni Galactose-specific lectin (PAL) 0.0016 0.0104 0.007
Schistosoma mansoni glutamate synthase 0.0069 0.0822 0.0791
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Loa Loa (eye worm) acetyltransferase 0.0055 0.0632 0.06
Schistosoma mansoni vesicular amine transporter 0.0111 0.1384 0.1355
Loa Loa (eye worm) hypothetical protein 0.0216 0.28 0.2775
Trypanosoma brucei NADH dehydrogenase 0.0069 0.0822 0.0822
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0011 0.0045 0.0011
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0016 0.011 0.0065
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0036 0.0379 0.0346
Entamoeba histolytica thioredoxin reductase, putative 0.0069 0.0822 0.2854
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Schistosoma mansoni loxhd1 0.0015 0.009 0.0056
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0379 0.0346
Echinococcus granulosus roundabout 2 0.0064 0.076 0.0728
Echinococcus granulosus thioredoxin glutathione reductase 0.0751 1 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Brugia malayi Leucine Rich Repeat family protein 0.0028 0.0273 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Echinococcus multilocularis hemicentin 1 0.0064 0.076 0.0728
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0069 0.0822 0.0822
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0069 0.0822 0.0781
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0025 0.0229 0.0196
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0015 0.009 0.0056
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0043 0.0475 0.0443
Loa Loa (eye worm) hypothetical protein 0.0011 0.0045 0.0011
Brugia malayi protein unc-22 0.003 0.0291 0.0258
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Echinococcus granulosus Immunoglobulin subtype 0.0036 0.0379 0.0346
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0025 0.0229 0.0229
Trichomonas vaginalis glutamate synthase, putative 0.0069 0.0822 0.2187
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0064 0.076 0.0728
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0822 0.0728
Echinococcus granulosus phospholipase A2 receptor 1 0.0016 0.0104 0.007
Leishmania major acetoin dehydrogenase e3 component-like protein 0.026 0.3395 0.3395
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0064 0.076 0.0728
Trichomonas vaginalis set domain proteins, putative 0.009 0.1101 0.3033
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Brugia malayi Cyclin, N-terminal domain containing protein 0.0202 0.2611 0.2586
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0069 0.0822 0.2854
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.003 0.0291 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Loa Loa (eye worm) hypothetical protein 0.0175 0.2251 0.2225
Echinococcus multilocularis glycogen phosphorylase 0.0052 0.0588 0.0555
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0147 0.187 0.1843
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0028 0.0273 0.024
Schistosoma mansoni roundabout 0.0064 0.076 0.0728
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0051 0.0051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.026 0.3395 1
Echinococcus granulosus Polycystic kidney disease protein 0.0015 0.009 0.0056
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Schistosoma mansoni cell adhesion molecule 0.0064 0.076 0.0728
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0069 0.0822 0.2854
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0028 0.0273 0.024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0064 0.076 0.0728
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.026 0.3395 0.3365
Echinococcus multilocularis Polycystic kidney disease protein 0.0015 0.009 0.0056
Loa Loa (eye worm) thioredoxin reductase 0.0751 1 1
Echinococcus granulosus defective proboscis extension response 0.0111 0.1384 0.1355
Onchocerca volvulus 0.003 0.0291 0.1475
Echinococcus granulosus titin 0.003 0.0291 0.0258
Echinococcus granulosus titin 0.0028 0.0273 0.024
Loa Loa (eye worm) programmed cell death 8 0.0069 0.0822 0.0791
Onchocerca volvulus 0.009 0.1101 0.6115
Schistosoma mansoni slit 0.0028 0.0273 0.024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Brugia malayi pregnancy-associated plasma protein-A 0.014 0.1778 0.175
Echinococcus multilocularis lachesin 0.0064 0.076 0.0728
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0822 0.0728
Brugia malayi hypothetical protein 0.0032 0.032 0.0287
Trypanosoma cruzi cruzipain precursor, putative 0.0024 0.0218 0.0117
Schistosoma mansoni hemicentin 0.0028 0.0273 0.024
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.026 0.3395 0.3372
Echinococcus multilocularis twitchin 0.003 0.0291 0.0258
Loa Loa (eye worm) hypothetical protein 0.0064 0.076 0.0728
Schistosoma mansoni cadherin 0.0016 0.0104 0.007
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0025 0.0229 0.0196
Schistosoma mansoni cell adhesion molecule 0.0147 0.187 0.1843
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0069 0.0822 0.0822
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.026 0.3395 0.3327
Loa Loa (eye worm) glutathione reductase 0.0751 1 1
Onchocerca volvulus 0.014 0.1778 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0088 0.1076 0.1045
Echinococcus multilocularis netrin receptor unc 5 0.0036 0.0379 0.0346
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0069 0.0822 0.0791
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0069 0.0822 0.0791
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Loa Loa (eye worm) CAMK protein kinase 0.003 0.0291 0.0258
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Echinococcus granulosus twitchin 0.014 0.1783 0.1755
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0022 0.0193 0.0193
Brugia malayi Cadherin domain containing protein 0.0076 0.0914 0.0883
Entamoeba histolytica hypothetical protein 0.0032 0.032 0.089
Entamoeba histolytica glycogen phosphorylase, putative 0.0052 0.0588 0.1938
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0069 0.0822 0.2187
Onchocerca volvulus 0.0015 0.009 0.0323
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0475 0.1499
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0079 0.0954 0.0923
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.026 0.3395 0.3395
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0102 0.0102
Echinococcus multilocularis Immunoglobulin 0.0111 0.1384 0.1355
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3327
Loa Loa (eye worm) hypothetical protein 0.0111 0.1384 0.1355
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0102 0.0102
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.026 0.3395 1
Echinococcus granulosus protein jagged 1 0.0076 0.0914 0.0883
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0069 0.0822 0.0822
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.026 0.3395 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.1384 0.1355
Brugia malayi polk-prov protein 0.0012 0.0051 0.0017
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Echinococcus multilocularis hemicentin 1 0.0064 0.076 0.0728
Loa Loa (eye worm) cyclin domain-containing protein 0.0202 0.2611 0.2586
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Onchocerca volvulus 0.0028 0.0273 0.1373
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0017
Loa Loa (eye worm) projectin 0.0028 0.0273 0.024
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0064 0.076 0.0728
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.026 0.3395 0.3327
Entamoeba histolytica hypothetical protein 0.0032 0.032 0.089
Echinococcus multilocularis phospholipase A2 receptor 1 0.0016 0.0104 0.007
Brugia malayi basement membrane proteoglycan 0.0036 0.0379 0.0346
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0069 0.0822 0.0822
Mycobacterium tuberculosis Probable oxidoreductase 0.026 0.3395 0.3395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0379 0.0346
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0475 0.1134
Echinococcus multilocularis fibropellin Ia 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0028 0.0273 0.024
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0016 0.011 0.0065
Echinococcus multilocularis transfer RNA-Phe 0.0028 0.0273 0.024
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.026 0.3395 0.3335
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.026 0.3395 0.3372
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0111 0.1384 0.1355
Echinococcus granulosus roundabout 2 0.0175 0.2251 0.2225
Schistosoma mansoni septate junction protein 0.0064 0.076 0.0728
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0069 0.0822 0.2187
Loa Loa (eye worm) disorganized muscle protein 1 0.0028 0.0273 0.024
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0156 0.199 0.1963
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0024 0.0218 0.0218
Brugia malayi Calcium binding EGF domain containing protein 0.0076 0.0914 0.0883
Echinococcus granulosus neurogenic locus notch protein 0.0076 0.0914 0.0883
Echinococcus granulosus nephrin 0.0028 0.0273 0.024
Giardia lamblia Glycogen phosphorylase 0.0052 0.0588 0.1731
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0069 0.0822 0.2187
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0028 0.0273 0.024
Echinococcus multilocularis tyrosine protein kinase otk 0.0064 0.076 0.0728
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Entamoeba histolytica cyclin C, putative 0.0205 0.2651 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Treponema pallidum NADH oxidase 0.026 0.3395 1
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0111 0.1384 0.1355
Schistosoma mansoni hypothetical protein 0.0028 0.0273 0.024
Echinococcus granulosus roundabout 2 0.0064 0.076 0.0728
Loa Loa (eye worm) hypothetical protein 0.0016 0.0104 0.007
Loa Loa (eye worm) hypothetical protein 0.0111 0.1384 0.1355
Schistosoma mansoni titin 0.0028 0.0273 0.024
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0036 0.0379 0.0346
Brugia malayi kettin 0.0028 0.0273 0.024
Onchocerca volvulus Netrin receptor homolog 0.0028 0.0273 0.1373
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3327
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0043 0.0475 0.0377
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0064 0.076 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0291 0.0258
Brugia malayi hypothetical protein 0.014 0.1778 0.175
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0102 0.0102
Echinococcus multilocularis insulin growth factor binding 0.0028 0.0273 0.024
Brugia malayi Pre-SET motif family protein 0.0011 0.0045 0.0011
Trypanosoma cruzi major cysteine proteinase, putative 0.0019 0.0148 0.0047
Echinococcus granulosus c4b binding protein beta chain 0.014 0.1778 0.175
Echinococcus granulosus Immunoglobulin 0.0111 0.1384 0.1355
Chlamydia trachomatis thioredoxin reductase 0.0069 0.0822 0.0836
Brugia malayi Fibronectin type III domain containing protein 0.0111 0.1384 0.1355
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0069 0.0822 0.2187
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Echinococcus granulosus titin 0.0028 0.0273 0.024
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0069 0.0822 0.2187
Echinococcus multilocularis glycogen phosphorylase 0.0052 0.0588 0.0555
Loa Loa (eye worm) hypothetical protein 0.014 0.1778 0.175
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0291 0.0258
Echinococcus multilocularis lymphocyte antigen 75 0.0016 0.0104 0.007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0069 0.0822 0.0791
Echinococcus multilocularis Immunoglobulin subtype 0.0036 0.0379 0.0346
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.026 0.3395 0.3327
Onchocerca volvulus Neurogenic locus notch homolog 0.0076 0.0914 0.5043
Loa Loa (eye worm) hypothetical protein 0.0028 0.0273 0.024
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0025 0.0229 0.0537
Loa Loa (eye worm) gastrulation defective protein 1 0.026 0.3386 0.3364
Schistosoma mansoni cell adhesion molecule 0.0036 0.0379 0.0346
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Onchocerca volvulus 0.0028 0.0273 0.1373
Loa Loa (eye worm) hypothetical protein 0.0069 0.0822 0.0791
Schistosoma mansoni myosin-binding protein-related 0.0028 0.0273 0.024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.026 0.3395 0.3395
Entamoeba histolytica disulphide oxidoreductase, putative 0.0069 0.0822 0.2854
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0064 0.076 0.0728
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0043 0.0475 0.0432
Plasmodium falciparum thioredoxin reductase 0.026 0.3395 0.3335
Echinococcus granulosus glycogen phosphorylase 0.0052 0.0588 0.0555
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0055 0.0632 0.06
Echinococcus multilocularis lipoxygenase domain containing protein 0.0015 0.009 0.0056
Echinococcus multilocularis neurogenic locus protein delta 0.0076 0.0914 0.0883
Loa Loa (eye worm) hypothetical protein 0.0076 0.0914 0.0883
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0025 0.0229 0.0129
Echinococcus granulosus tyrosine protein kinase otk 0.0064 0.076 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.0273 0.024
Schistosoma mansoni titin 0.0064 0.076 0.0728
Echinococcus granulosus fras1 related extracellular matrix protein 0.0016 0.0104 0.007
Plasmodium vivax glycogen synthase kinase 3, putative 0.0043 0.0475 0.0432
Schistosoma mansoni glycogen phosphorylase 0.0052 0.0588 0.0555
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0379 0.0346
Brugia malayi glutamate synthase 0.0069 0.0822 0.0791
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0147 0.187 0.1843
Schistosoma mansoni rab6-interacting 0.0015 0.009 0.0056
Onchocerca volvulus 0.0028 0.0273 0.1373
Onchocerca volvulus 0.0016 0.0104 0.0402
Echinococcus granulosus lipoxygenase domain containing protein 0.0015 0.009 0.0056
Schistosoma mansoni c4b-binding protein beta chain 0.014 0.1778 0.175
Echinococcus multilocularis fras1 related extracellular matrix protein 0.0016 0.0104 0.007
Brugia malayi Cadherin domain containing protein 0.0076 0.0914 0.0883
Echinococcus multilocularis protein jagged 2 0.0076 0.0914 0.0883
Mycobacterium ulcerans hypothetical protein 0.0069 0.0822 0.2187
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.0273 0.024
Brugia malayi Lectin C-type domain containing protein 0.0016 0.0104 0.007
Schistosoma mansoni nephrin 0.0064 0.076 0.0728
Loa Loa (eye worm) hypothetical protein 0.0111 0.1384 0.1355

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = -19 % Inhibition of human Prostaglandin G/H synthase 1 at 0.1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -19 % Inhibition of human Prostaglandin G/H synthase 1 at 0.1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -15 % Inhibition of human Prostaglandin G/H synthase 2 at 0.1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -15 % Inhibition of human Prostaglandin G/H synthase 2 at 0.1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -4 % Inhibition of human Prostaglandin G/H synthase 2 at 1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -4 % Inhibition of human Prostaglandin G/H synthase 2 at 1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -3 % Inhibition of human Prostaglandin G/H synthase 1 at 1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = -3 % Inhibition of human Prostaglandin G/H synthase 1 at 1 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = 19 % Inhibition of human Prostaglandin G/H synthase 1 at 10 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = 19 % Inhibition of human Prostaglandin G/H synthase 1 at 10 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = 60 % Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488
Inhibition (binding) = 60 % Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as mean percent inhibition of control PGE-2 production ChEMBL. 9083488

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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