Detailed information for compound 312758

Basic information

Technical information
  • TDR Targets ID: 312758
  • Name: 4-[(E)-(3,5-difluorophenoxy)iminomethyl]benzo ic acid
  • MW: 277.223 | Formula: C14H9F2NO3
  • H donors: 1 H acceptors: 2 LogP: 3.25 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1ccc(cc1)/C=N/Oc1cc(F)cc(c1)F
  • InChi: 1S/C14H9F2NO3/c15-11-5-12(16)7-13(6-11)20-17-8-9-1-3-10(4-2-9)14(18)19/h1-8H,(H,18,19)/b17-8+
  • InChiKey: PLGMZOTUYREITK-CAOOACKPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[(E)-(3,5-difluorophenyl)oximinomethyl]benzoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.0444 0.086 0.086
Giardia lamblia Kinase, CMGC CLK 0.0335 0.0577 0.1759
Trichomonas vaginalis AGC family protein kinase 0.039 0.0719 0.2194
Onchocerca volvulus Serine\/threonine kinase homolog 0.0588 0.123 0.5765
Brugia malayi Protein kinase domain containing protein 0.0143 0.0082 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Brugia malayi Protein kinase domain containing protein 0.2044 0.4993 0.4982
Echinococcus granulosus leucine rich repeat containing protein 4 0.0182 0.0183 0.0175
Schistosoma mansoni cell adhesion molecule 0.0202 0.0235 0.0235
Echinococcus multilocularis dual specificity 0.0303 0.0494 0.0486
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0797 0.1771 0.1764
Brugia malayi protein kinase C II. 0.0444 0.086 0.0839
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0185 0.019 0.0182
Onchocerca volvulus 0.0182 0.0183 0.0759
Entamoeba histolytica casein kinase, putative 0.0237 0.0325 0.1616
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0494 0.1509
Brugia malayi Egg laying defective protein 4 0.0185 0.019 0.0169
Entamoeba histolytica thioredoxin reductase, putative 0.0366 0.0659 0.3279
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.028 0.0437 0.0437
Schistosoma mansoni cell adhesion molecule 0.0421 0.08 0.08
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0174 0.0161 0.0153
Echinococcus multilocularis neural cadherin 0.0402 0.0752 0.0744
Entamoeba histolytica hypothetical protein 0.0266 0.0401 0.1994
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0366 0.0659 0.0651
Echinococcus multilocularis CDC7 cell division cycle 7 0.0196 0.0219 0.021
Giardia lamblia Kinase, PLK 0.0588 0.123 0.3753
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0366 0.0659 0.3279
Echinococcus multilocularis titin 0.0182 0.0183 0.0175
Loa Loa (eye worm) hypothetical protein 0.031 0.0513 0.0504
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0473 0.0935 0.0926
Mycobacterium ulcerans monoxygenase 0.0366 0.0659 0.2004
Giardia lamblia Kinase, CMGC MAPK 0.0183 0.0185 0.0564
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.0376 0.0376
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0341 0.0593 0.0593
Brugia malayi glutamate synthase 0.0366 0.0659 0.0638
Echinococcus granulosus fibroblast growth factor receptor 4 0.0395 0.0734 0.0726
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0239 0.033 0.032
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0275 0.0422 0.0413
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0183 0.0185 0.0176
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus multilocularis protein tyrosine kinase 0.063 0.1339 0.1332
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0255 0.0372 0.0351
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0235 0.0213
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0242 0.0339 0.0339
Trichomonas vaginalis AGC family protein kinase 0.0257 0.0376 0.1148
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0588 0.123 0.1223
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0219 0.0278 0.0278
Echinococcus multilocularis twitchin 0.0255 0.0371 0.0363
Plasmodium falciparum cGMP-dependent protein kinase 0.0185 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0301 0.049 0.0481
Brugia malayi C1-like domain containing protein 0.0473 0.0935 0.0915
Brugia malayi Protein kinase domain containing protein 0.0437 0.0841 0.082
Echinococcus granulosus nervana 2 0.0268 0.0405 0.0397
Echinococcus multilocularis myosin iiia 0.0185 0.019 0.0182
Brugia malayi EGF-like domain containing protein 0.0402 0.0752 0.0732
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0333 0.0573 0.0565
Schistosoma mansoni sulfide quinone reductase 0.0366 0.0659 0.0659
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0155 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0366 0.0659 0.0659
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0257 0.0376 0.0368
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0183 0.0185 0.0185
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0335 0.0577 0.0577
Echinococcus multilocularis 0.021 0.0255 0.0247
Onchocerca volvulus 0.0743 0.1632 0.7686
Schistosoma mansoni serine/threonine protein kinase 0.0357 0.0635 0.0635
Echinococcus granulosus tyrosine protein kinase Fyn 0.0333 0.0573 0.0565
Loa Loa (eye worm) TK/EGFR protein kinase 0.0758 0.1669 0.1661
Schistosoma mansoni adapter molecule crk 0.0134 0.0058 0.0058
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0421 0.08 0.0792
Leishmania major protein kinase, putative 0.0144 0.0083 0.0083
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Schistosoma mansoni cell adhesion molecule 0.0182 0.0183 0.0183
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0766 0.1691 0.1683
Brugia malayi phosphoinositide-dependent protein kinase I 0.0178 0.0172 0.0151
Echinococcus granulosus titin 0.0182 0.0183 0.0175
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0357 0.0635 0.0626
Onchocerca volvulus 0.0707 0.1537 0.7235
Loa Loa (eye worm) hypothetical protein 0.0503 0.1012 0.1003
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0366 0.0659 0.0659
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.138 0.3277 0.3277
Schistosoma mansoni laminin gamma-3 chain 0.0402 0.0752 0.0752
Loa Loa (eye worm) hypothetical protein 0.0301 0.049 0.0481
Leishmania major protein kinase, putative 0.0335 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0219 0.0278 0.0269
Loa Loa (eye worm) hypothetical protein 0.0262 0.0389 0.0379
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0441 0.0851 0.0831
Brugia malayi Protein kinase domain containing protein 0.0332 0.057 0.055
Echinococcus multilocularis dual specificity 0.0266 0.0401 0.0393
Schistosoma mansoni tyrosine kinase 0.0333 0.0573 0.0573
Schistosoma mansoni septate junction protein 0.0219 0.0278 0.0278
Brugia malayi Protein kinase domain containing protein 0.0178 0.0172 0.0151
Leishmania major hypothetical protein, conserved 0.0366 0.0659 0.0659
Loa Loa (eye worm) TK/EPH protein kinase 0.0248 0.0353 0.0343
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.028 0.0437 0.0437
Trichomonas vaginalis CAMK family protein kinase 0.0588 0.123 0.3753
Brugia malayi Leucine Rich Repeat family protein 0.0183 0.0185 0.0163
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0722 0.1579 0.156
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0242 0.0339 0.033
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0533 0.1089 0.1081
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.028 0.0437 0.0437
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0178 0.0172 0.0163
Trichomonas vaginalis AGC family protein kinase 0.0246 0.0349 0.1065
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Plasmodium falciparum calcium-dependent protein kinase 3 0.022 0.0281 0.0281
Brugia malayi hypothetical protein 0.0738 0.162 0.1601
Echinococcus multilocularis protein jagged 2 0.0402 0.0752 0.0744
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3983 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0588 0.123 0.3753
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Toxoplasma gondii EGF family domain-containing protein 0.0402 0.0752 0.0752
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0183 0.0185 0.0185
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0303 0.0494 0.0494
Echinococcus granulosus neuroglian 0.0901 0.2039 0.2032
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0421 0.08 0.0792
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0185 0.0564
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0183
Leishmania major protein kinase, putative 0.0185 0.019 0.019
Echinococcus multilocularis neuroglian 0.0421 0.08 0.0792
Plasmodium falciparum calcium-dependent protein kinase 4 0.022 0.0281 0.0281
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0401 0.0749 0.0749
Echinococcus granulosus tyrosine protein kinase otk 0.0401 0.0749 0.0741
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0441 0.0851 0.0842
Echinococcus multilocularis neurogenic locus notch protein 0.0402 0.0752 0.0744
Echinococcus granulosus tyrosine protein kinase HCK 0.0199 0.0227 0.0219
Echinococcus granulosus fibropellin Ia 0.0402 0.0752 0.0744
Onchocerca volvulus 0.0164 0.0137 0.0536
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0366 0.0659 0.201
Trichomonas vaginalis AGC family protein kinase 0.0367 0.066 0.2014
Echinococcus multilocularis serine:threonine protein kinase N2 0.0632 0.1345 0.1337
Echinococcus granulosus tyrosine protein kinase Fyn 0.0333 0.0573 0.0565
Schistosoma mansoni protein kinase 0.0144 0.0083 0.0083
Brugia malayi Calcium binding EGF domain containing protein 0.0402 0.0752 0.0732
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0182 0.0183 0.0175
Giardia lamblia Kinase, CMGC SRPK 0.0182 0.0181 0.0554
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0246 0.0349 0.0349
Echinococcus granulosus serine:threonine protein kinase MARK2 0.047 0.0926 0.0918
Schistosoma mansoni tyrosine kinase 0.0205 0.0241 0.0241
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0259 0.0381 0.0372
Echinococcus granulosus glutamate synthase 0.0366 0.0659 0.0651
Schistosoma mansoni protein kinase 0.0333 0.0574 0.0574
Echinococcus granulosus nephrin 0.0202 0.0235 0.0226
Onchocerca volvulus Putative titin 0.0182 0.0183 0.0759
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0346 0.0607 0.0607
Echinococcus granulosus Immunoglobulin 0.0219 0.0278 0.027
Trypanosoma cruzi casein kinase, putative 0.0237 0.0325 0.0325
Trypanosoma cruzi casein kinase, putative 0.0237 0.0325 0.0325
Schistosoma mansoni ephrin receptor 0.021 0.0254 0.0254
Onchocerca volvulus 0.0182 0.0183 0.0759
Loa Loa (eye worm) hypothetical protein 0.0392 0.0724 0.0715
Brugia malayi Disorganized muscle protein 1 0.0182 0.0183 0.0162
Brugia malayi Furin-like cysteine rich region family protein 0.0758 0.1669 0.1651
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0266 0.0401 0.0391
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0172 0.0526
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Trichomonas vaginalis CMGC family protein kinase 0.0196 0.0219 0.0667
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0766 0.1691 0.1683
Brugia malayi small heat shock protein 0.0587 0.1229 0.1209
Echinococcus multilocularis epidermal growth factor receptor 0.0758 0.1669 0.1662
Entamoeba histolytica protein kinase, putative 0.028 0.0437 0.2174
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0239 0.033 0.0321
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0202 0.0235 0.0226
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0242 0.0339 0.033
Echinococcus multilocularis mitogen activated protein kinase 0.0183 0.0185 0.0177
Schistosoma mansoni hypothetical protein 0.0219 0.0278 0.0278
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0533 0.1089 0.1082
Brugia malayi serine/threonine kinase 12 0.0257 0.0376 0.0355
Echinococcus granulosus calcium dependent protein kinase 0.0147 0.0093 0.0084
Loa Loa (eye worm) CAMK protein kinase 0.0275 0.0422 0.0413
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0674 0.1454 0.1447
Onchocerca volvulus 0.0743 0.1632 0.7686
Brugia malayi Protein kinase domain containing protein 0.0464 0.0911 0.089
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0574 0.1196 0.1188
Schistosoma mansoni titin 0.0182 0.0183 0.0183
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.047 0.0926 0.0918
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0335 0.0577 0.0577
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0303 0.0494 0.0474
Schistosoma mansoni basigin related 0.0219 0.0278 0.0278
Echinococcus granulosus N chimaerin 0.0163 0.0133 0.0124
Echinococcus granulosus tyrosine protein kinase shark 0.0379 0.0691 0.0683
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0366 0.0659 0.0651
Brugia malayi serine/threonine-protein kinase PAK 7 0.0505 0.1016 0.0996
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0401 0.0749 0.3464
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0242 0.0339 0.0339
Plasmodium falciparum glutathione reductase 0.3983 1 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.028 0.0437 0.0429
Schistosoma mansoni growth factor receptor-bound protein 0.0136 0.0064 0.0064
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0877 0.1977 0.197
Brugia malayi Immunoglobulin I-set domain containing protein 0.0578 0.1204 0.1185
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0303 0.0494 0.0485
Echinococcus granulosus tyrosine protein kinase Fyn 0.0333 0.0573 0.0565
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0341 0.0593 0.0585
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0366 0.0659 0.0651
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0237 0.0325 0.0315
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0366 0.0659 0.0659
Schistosoma mansoni serine/threonine protein kinase 0.0574 0.1196 0.1196
Loa Loa (eye worm) hypothetical protein 0.0719 0.157 0.1562
Echinococcus multilocularis N chimaerin 0.0163 0.0133 0.0124
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0242 0.0339 0.0339
Trypanosoma cruzi aurora B kinase, putative 0.0257 0.0376 0.0376
Brugia malayi SRC-1 0.0333 0.0573 0.0552
Trichomonas vaginalis apoptosis inducing factor, putative 0.0366 0.0659 0.201
Trypanosoma cruzi p21-activated kinase 3, putative 0.012 0.0022 0.0022
Brugia malayi Protein kinase domain containing protein 0.0422 0.0801 0.0781
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0268 0.0405 0.0397
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0145 0.0086 0.043
Echinococcus multilocularis cyclin dependent kinase 9 0.0165 0.0138 0.013
Loa Loa (eye worm) hypothetical protein 0.0401 0.0749 0.074
Loa Loa (eye worm) notch protein 0.0402 0.0752 0.0743
Echinococcus multilocularis casein kinase I alpha 0.0237 0.0325 0.0316
Schistosoma mansoni slit 0.0403 0.0753 0.0753
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0421 0.08 0.08
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0219 0.0278 0.0278
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0381 0.1164
Echinococcus granulosus c-Jun N-terminal kinases 0.0574 0.1196 0.1189
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Echinococcus granulosus Immunoglobulin 0.0718 0.1568 0.1561
Schistosoma mansoni hypothetical protein 0.0219 0.0278 0.0278
Giardia lamblia Kinase, CAMK CAMKL 0.0187 0.0196 0.0599
Brugia malayi EGF-like domain containing protein 0.0402 0.0752 0.0732
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0361 0.11
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0219 0.0278 0.0269
Echinococcus multilocularis nervana 2 0.0268 0.0405 0.0397
Echinococcus multilocularis 0.0262 0.0389 0.0381
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Brugia malayi Immunoglobulin I-set domain containing protein 0.0401 0.0749 0.0729
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0366 0.0659 0.201
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0366 0.0659 0.0651
Brugia malayi Immunoglobulin I-set domain containing protein 0.0401 0.0749 0.0729
Leishmania major trypanothione reductase 0.3983 1 1
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Loa Loa (eye worm) hypothetical protein 0.0421 0.08 0.0791
Toxoplasma gondii AGC kinase 0.0246 0.0349 0.0349
Echinococcus multilocularis Immunoglobulin 0.0718 0.1568 0.1561
Schistosoma mansoni serine/threonine protein kinase 0.0632 0.1345 0.1345
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.022 0.0281 0.0281
Echinococcus multilocularis neurogenic locus notch protein 0.0402 0.0752 0.0744
Loa Loa (eye worm) hypothetical protein 0.112 0.2605 0.2597
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0219 0.0278 0.027
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0366 0.0659 0.201
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0134 0.0058 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.053 0.1082 0.1082
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0366 0.0659 0.2004
Trichomonas vaginalis AGC family protein kinase 0.0257 0.0376 0.1148
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Loa Loa (eye worm) casein kinase 0.0391 0.0723 0.0713
Echinococcus multilocularis C type lectin domian containing protein 0.0743 0.1632 0.1625
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0163 0.0133 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0183 0.0185 0.0185
Echinococcus granulosus twitchin 0.0973 0.2227 0.222
Echinococcus multilocularis dual specificity protein kinase clk2 0.0335 0.0577 0.0569
Schistosoma mansoni vam6/vps39 related 0.0242 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.0738 0.162 0.1611
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0134 0.0058 0.0048
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0341 0.0593 0.0593
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0481 0.0955 0.0947
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0235 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1032 0.1032
Brugia malayi Prion-like- 0.0182 0.0183 0.0162
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0366 0.0659 0.0659
Echinococcus multilocularis casein kinase I delta 0.0237 0.0325 0.0316
Onchocerca volvulus 0.0275 0.0422 0.1903
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0419 0.0796 0.0787
Echinococcus multilocularis transfer RNA-Phe 0.0202 0.0235 0.0226
Echinococcus granulosus neurogenic locus protein delta 0.0402 0.0752 0.0744
Plasmodium vivax serine/threonine protein kinase, putative 0.0182 0.0181 0.0181
Entamoeba histolytica protein kinase, putative 0.0351 0.0618 0.3077
Echinococcus multilocularis hemicentin 1 0.0401 0.0749 0.0741
Toxoplasma gondii AGC kinase 0.0619 0.1311 0.1311
Echinococcus multilocularis tyrosine protein kinase Abl 0.0205 0.0241 0.0233
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0718 0.1568 0.1568
Brugia malayi Cyclin C 0.1753 0.424 0.4227
Plasmodium falciparum glutathione reductase 0.138 0.3277 0.3277
Echinococcus multilocularis glutamate synthase 0.0366 0.0659 0.0651
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.138 0.3277 1
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Entamoeba histolytica protein kinase domain containing protein 0.0303 0.0494 0.2461
Echinococcus multilocularis peroxidasin 0.0402 0.075 0.0742
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Onchocerca volvulus 0.0183 0.0185 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0349 0.0349
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Schistosoma mansoni kinase 0.0165 0.0138 0.0138
Giardia lamblia Kinase, NEK 0.0297 0.0479 0.146
Loa Loa (eye worm) TK protein kinase 0.0578 0.1204 0.1196
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.138 0.3277 0.2803
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0183
Schistosoma mansoni tyrosine kinase 0.0333 0.0573 0.0573
Plasmodium vivax ferrodoxin reductase, putative 0.0366 0.0659 0.0659
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0112 0.0001 0.0004
Trichomonas vaginalis CMGC family protein kinase 0.0335 0.0577 0.1759
Loa Loa (eye worm) hypothetical protein 0.0219 0.0278 0.0269
Plasmodium falciparum serine/threonine protein kinase, putative 0.0257 0.0376 0.0376
Onchocerca volvulus 0.0301 0.049 0.2226
Echinococcus granulosus serine:threonine protein kinase N2 0.0281 0.0439 0.0431
Trypanosoma cruzi trypanothione reductase, putative 0.3983 1 1
Toxoplasma gondii histone kinase SNF1, putative 0.0171 0.0155 0.0155
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0163 0.0133 0.0124
Echinococcus multilocularis epidermal growth factor receptor 0.0528 0.1075 0.1068
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0183
Brugia malayi Fibronectin type III domain containing protein 0.0738 0.162 0.1601
Echinococcus granulosus Glutaredoxin protein 5 0.0268 0.0405 0.0397
Echinococcus granulosus low density lipoprotein receptor ldl 0.0219 0.0278 0.027
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Plasmodium vivax unspecified product 0.0218 0.0277 0.0277
Echinococcus multilocularis casein kinase I alpha 0.0237 0.0325 0.0316
Brugia malayi Cadherin domain containing protein 0.0402 0.0752 0.0732
Toxoplasma gondii rhoptry neck protein RON1 0.0743 0.1632 0.1632
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0185 0.019 0.019
Schistosoma mansoni nephrin related 0.0182 0.0183 0.0183
Echinococcus granulosus mitogen activated protein kinase 14 0.0346 0.0607 0.0599
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0381 0.1164
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0177 0.017 0.017
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0401 0.0749 0.074
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0421 0.08 0.0792
Loa Loa (eye worm) AUR protein kinase 0.0257 0.0376 0.0367
Schistosoma mansoni glutamate synthase 0.0366 0.0659 0.0659
Schistosoma mansoni hypothetical protein 0.0219 0.0278 0.0278
Onchocerca volvulus 0.0143 0.0082 0.0273
Echinococcus granulosus serine:threonine protein kinase 3 0.0558 0.1155 0.1147
Loa Loa (eye worm) CMGC/GSK protein kinase 0.028 0.0437 0.0427
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0511 0.1032 0.1025
Entamoeba histolytica cell division protein kinase 2, putative 0.0275 0.0423 0.2106
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Echinococcus granulosus peroxidasin 0.0402 0.075 0.0742
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0366 0.0659 0.201
Schistosoma mansoni tyrosine kinase 0.063 0.1339 0.1339
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.022 0.0281 0.0273
Onchocerca volvulus 0.0402 0.0752 0.3479
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Echinococcus granulosus serine:threonine kinase SAD 1 0.0171 0.0155 0.0146
Toxoplasma gondii AGC kinase 0.0246 0.0349 0.0349
Loa Loa (eye worm) CDC7 protein kinase 0.0196 0.0219 0.0209
Echinococcus granulosus protein kinase c epsilon type 0.0444 0.086 0.0852
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Schistosoma mansoni septate junction protein 0.0401 0.0749 0.0749
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0366 0.0659 0.065
Onchocerca volvulus 0.0417 0.079 0.3659
Onchocerca volvulus Putative cubilin 0.0402 0.0752 0.3479
Brugia malayi Immunoglobulin I-set domain containing protein 0.0401 0.0749 0.0729
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0366 0.0659 0.201
Brugia malayi serine/threonine-protein kinase 6 0.0257 0.0376 0.0355
Echinococcus multilocularis thioredoxin glutathione reductase 0.3983 1 1
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0259 0.0381 0.0372
Schistosoma mansoni hypothetical protein 0.0221 0.0283 0.0283
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0163 0.0133 0.0133
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Leishmania major dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Schistosoma mansoni protein kinase 0.0481 0.0955 0.0955
Loa Loa (eye worm) AGC/PKG protein kinase 0.0185 0.019 0.0181
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Brugia malayi Immunoglobulin I-set domain containing protein 0.0239 0.033 0.0308
Echinococcus granulosus mitogen activated protein kinase 3 0.0183 0.0185 0.0177
Echinococcus multilocularis titin 0.0275 0.0422 0.0414
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0259 0.0381 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.0202 0.0235 0.0225
Toxoplasma gondii thioredoxin reductase 0.3983 1 1
Loa Loa (eye worm) hypothetical protein 0.0652 0.1396 0.1387
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0281 0.0281
Onchocerca volvulus 0.0143 0.0082 0.0273
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0205 0.0241 0.0241
Schistosoma mansoni hypothetical protein 0.0219 0.0278 0.0278
Brugia malayi Protein kinase domain containing protein 0.0335 0.0577 0.0556
Brugia malayi Cyclin, N-terminal domain containing protein 0.0877 0.1977 0.1959
Brugia malayi Protein kinase domain containing protein 0.0182 0.0181 0.016
Echinococcus multilocularis serine:threonine protein kinase 0.0249 0.0355 0.0347
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.022 0.0281 0.0271
Entamoeba histolytica protein kinase, putative 0.0199 0.0227 0.113
Echinococcus multilocularis lachesin 0.0401 0.0749 0.0741
Plasmodium falciparum glycogen synthase kinase 3 0.028 0.0437 0.0437
Entamoeba histolytica protein kinase, putative 0.0115 0.0009 0.0043
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0235 0.0225
Brugia malayi hypothetical protein 0.0143 0.0082 0.006
Schistosoma mansoni tyrosine kinase 0.0457 0.0892 0.0892
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Brugia malayi Serine/threonine-protein kinase SULU 0.0483 0.0961 0.0941
Loa Loa (eye worm) glutathione reductase 0.3983 1 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Onchocerca volvulus 0.0402 0.0752 0.3479
Trichomonas vaginalis STE family protein kinase 0.0185 0.019 0.058
Schistosoma mansoni nephrin 0.0921 0.209 0.209
Brugia malayi STE20-like kinase MST 0.0558 0.1155 0.1135
Echinococcus granulosus casein kinase ii subunit alpha 0.0218 0.0277 0.0268
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.022 0.0281 0.0281
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0471 0.0471
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0235 0.0213
Loa Loa (eye worm) AGC/NDR protein kinase 0.0351 0.0618 0.0609
Plasmodium vivax apical sushi protein, putative 0.0743 0.1632 0.1632
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0366 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Schistosoma mansoni cell adhesion molecule 0.0202 0.0235 0.0235
Echinococcus multilocularis nervana 2 0.0268 0.0405 0.0397
Brugia malayi Muscle positioning protein 4 0.0402 0.0752 0.0732
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0253 0.0366 0.0358
Brugia malayi Peroxidasin 0.0402 0.075 0.073
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.022 0.0281 0.0281
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0266 0.0401 0.0401
Brugia malayi Protein kinase domain 0.0188 0.0198 0.0176
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Echinococcus multilocularis expressed protein 0.0182 0.0181 0.0173
Loa Loa (eye worm) hypothetical protein 0.0407 0.0764 0.0755
Onchocerca volvulus 0.028 0.0437 0.1971
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0366 0.0659 0.0659
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0366 0.0659 0.0659
Loa Loa (eye worm) gastrulation defective protein 1 0.111 0.2579 0.2572
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Schistosoma mansoni hypothetical protein 0.0221 0.0283 0.0283
Entamoeba histolytica protein kinase, putative 0.0266 0.0401 0.1994
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0172 0.0172
Schistosoma mansoni protein kinase 0.0576 0.12 0.12
Echinococcus multilocularis casein kinase I delta 0.0237 0.0325 0.0316
Trypanosoma brucei casein kinase I, isoform 2 0.0237 0.0325 0.0325
Brugia malayi Immunoglobulin I-set domain containing protein 0.0219 0.0278 0.0257
Schistosoma mansoni titin 0.0182 0.0183 0.0183
Brugia malayi hypothetical protein 0.0483 0.0961 0.0941
Echinococcus multilocularis serine threonine protein kinase 0.0439 0.0847 0.084
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0346 0.0607 0.0598
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0856 0.1924 0.1916
Trypanosoma brucei hypothetical protein, conserved 0.0366 0.0659 0.0659
Entamoeba histolytica protein kinase domain containing protein 0.028 0.0437 0.2174
Trypanosoma brucei cdc2-related kinase 3 0.0259 0.0381 0.0381
Brugia malayi Immunoglobulin I-set domain containing protein 0.0421 0.08 0.078
Echinococcus multilocularis tyrosine protein kinase Srms 0.0271 0.0413 0.0405
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.138 0.3277 0.2803
Onchocerca volvulus 0.0402 0.0752 0.3479
Leishmania major protein kinase, putative 0.0257 0.0376 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0494 0.1509
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0246 0.0349 0.0328
Trichomonas vaginalis mercuric reductase, putative 0.138 0.3277 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0499 0.1002 0.0994
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0171 0.0155 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0826 0.1847 0.1839
Trypanosoma cruzi trypanothione reductase, putative 0.138 0.3277 0.3277
Toxoplasma gondii rhoptry neck protein RON9 0.0743 0.1632 0.1632
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0249 0.0355 0.0346
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Schistosoma mansoni c4b-binding protein beta chain 0.0743 0.1632 0.1632
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0574 0.1196 0.1189
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Loa Loa (eye worm) hypothetical protein 0.0699 0.1518 0.151
Echinococcus granulosus tyrosine protein kinase Src42A 0.0333 0.0573 0.0565
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.022 0.0281 0.0273
Onchocerca volvulus 0.0182 0.0183 0.0759
Giardia lamblia Thioredoxin reductase 0.0366 0.0659 0.201
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0588 0.123 0.123
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0335 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0301 0.049 0.0481
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0366 0.0659 0.0659
Brugia malayi Protein kinase domain containing protein 0.0336 0.058 0.0559
Schistosoma mansoni serine/threonine protein kinase 0.0464 0.0911 0.0911
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Brugia malayi P38 map kinase family protein 2 0.0346 0.0607 0.0587
Schistosoma mansoni protein kinase 0.0942 0.2147 0.2147
Schistosoma mansoni septate junction protein 0.0402 0.0752 0.0752
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.138 0.3277 0.3277
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Echinococcus multilocularis neurogenic locus notch protein 4 0.0402 0.0752 0.0744
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0743 0.1632 0.1624
Plasmodium vivax glutathione reductase, putative 0.3983 1 1
Echinococcus multilocularis titin 0.0182 0.0183 0.0175
Entamoeba histolytica cyclin C, putative 0.0889 0.2009 1
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0373 0.0677 0.0667
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0494 0.1509
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0441 0.0851 0.0843
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0271 0.0413 0.0405
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0494 0.1509
Entamoeba histolytica protein kinase, putative 0.0115 0.0009 0.0043
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0942 0.2147 0.214
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0333 0.0573 0.0565
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0183 0.0174
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0366 0.0659 0.0659
Schistosoma mansoni growth factor receptor-bound protein 0.0134 0.0058 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0577 0.0577
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0242 0.0339 0.0339
Giardia lamblia Kinase, CMGC GSK 0.028 0.0437 0.1333
Loa Loa (eye worm) one IG domain family member 0.0182 0.0183 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0185 0.0185
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Treponema pallidum NADH oxidase 0.138 0.3277 1
Toxoplasma gondii casein kinase I 0.0237 0.0325 0.0325
Echinococcus granulosus cyclin dependent kinase 0.0259 0.0381 0.0373
Leishmania major hypothetical protein, conserved 0.0366 0.0659 0.0659
Brugia malayi Tyrosine-protein kinase abl-1 0.0205 0.0241 0.022
Giardia lamblia Kinase, AGC PKA 0.0341 0.0593 0.181
Echinococcus granulosus neurogenic locus notch protein 4 0.0402 0.0752 0.0744
Brugia malayi Variant SH3 domain containing protein 0.0134 0.0058 0.0036
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0366 0.0659 0.0651
Schistosoma mansoni hypothetical protein 0.0219 0.0278 0.0278
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0366 0.0659 0.0659
Onchocerca volvulus 0.0366 0.0659 0.3033
Schistosoma mansoni protein kinase 0.0188 0.0198 0.0198
Trichomonas vaginalis CAMK family protein kinase 0.0588 0.123 0.3753
Entamoeba histolytica protein kinase, putative 0.0157 0.0119 0.0591
Loa Loa (eye worm) hypothetical protein 0.0177 0.0169 0.0159
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0188 0.0198 0.0189
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.138 0.3277 0.3277
Schistosoma mansoni serine/threonine-protein kinase 0.0357 0.0636 0.0636
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0333 0.0573 0.0565
Plasmodium falciparum apical sushi protein 0.0743 0.1632 0.1632
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0357 0.0636 0.0636
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0303 0.0494 0.0494
Echinococcus multilocularis casein kinase I alpha 0.0237 0.0325 0.0316
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Brugia malayi Prion-like- 0.0182 0.0183 0.0162
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0219 0.0278 0.027
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0315 0.0527 0.0519
Echinococcus multilocularis cyclin 0.0877 0.1977 0.197
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0188 0.0198 0.0189
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0297 0.0479 0.0479
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0483 0.0961 0.0953
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0253 0.0366 0.0358
Loa Loa (eye worm) TK protein kinase 0.0199 0.0227 0.0218
Trypanosoma cruzi cdc2-related kinase 1 0.0259 0.0381 0.0381
Loa Loa (eye worm) AGC/PKA protein kinase 0.0246 0.0349 0.034
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Echinococcus multilocularis titin 0.0182 0.0183 0.0175
Echinococcus granulosus ephrin type A receptor 4 A 0.021 0.0254 0.0246
Echinococcus granulosus mitogen activated protein kinase 11 0.0346 0.0607 0.0599
Plasmodium vivax calcium-dependent protein kinase, putative 0.022 0.0281 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.022 0.0281 0.0857
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0333 0.0574 0.0565
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0366 0.0659 0.201
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0183 0.0185 0.0185
Schistosoma mansoni cell adhesion molecule 0.0401 0.0749 0.0749
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0259 0.0381 0.0381
Onchocerca volvulus 0.0182 0.0183 0.0759
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Echinococcus multilocularis tyrosine kinase 0.0143 0.0082 0.0073
Loa Loa (eye worm) hypothetical protein 0.0451 0.0877 0.0868
Onchocerca volvulus 0.0196 0.0219 0.0929
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0366 0.0659 0.3279
Brugia malayi casein kinase 1, delta 0.0237 0.0325 0.0303
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.138 0.3277 1
Echinococcus granulosus serine:threonine protein kinase 0.0249 0.0355 0.0347
Schistosoma mansoni cell polarity protein 0.0402 0.0752 0.0752
Giardia lamblia Kinase, NEK 0.0297 0.0479 0.146
Echinococcus granulosus protein jagged 1 0.0402 0.0752 0.0744
Schistosoma mansoni protein kinase 0.0257 0.0376 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0361 0.11
Brugia malayi Sushi domain 0.0743 0.1632 0.1613
Echinococcus multilocularis protein kinase shaggy 0.028 0.0437 0.0429
Entamoeba histolytica PH domain containing protein kinase, putative 0.0357 0.0636 0.3165
Plasmodium falciparum serine/threonine protein kinase KIN 0.0171 0.0155 0.0155
Onchocerca volvulus Peroxidasin homolog 0.0183 0.0185 0.0766
Entamoeba histolytica protein kinase domain containing protein 0.0266 0.0401 0.1994
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0558 0.1155 0.1146
Trypanosoma brucei cdc2-related kinase 1 0.0259 0.0381 0.0381
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0366 0.0659 0.0651
Echinococcus multilocularis mitogen activated protein kinase 11 0.0346 0.0607 0.0599
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.138 0.3277 0.3263
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Echinococcus granulosus cyclin 0.0877 0.1977 0.197
Echinococcus granulosus neurogenic locus notch protein 0.0402 0.0752 0.0744
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0366 0.0659 0.0659
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0171 0.0155 0.0155
Brugia malayi probable protein kinase 0.0576 0.12 0.1181
Loa Loa (eye worm) hypothetical protein 0.0401 0.0749 0.074
Loa Loa (eye worm) hypothetical protein 0.0242 0.0339 0.0329
Schistosoma mansoni titin 0.0401 0.0749 0.0749
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0499 0.1002 0.0994
Echinococcus granulosus titin 0.0182 0.0183 0.0175
Schistosoma mansoni titin 0.0182 0.0183 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0471 0.0471
Loa Loa (eye worm) hypothetical protein 0.0219 0.0278 0.0269
Loa Loa (eye worm) hypothetical protein 0.0219 0.0278 0.0269
Schistosoma mansoni tyrosine kinase 0.0472 0.0932 0.0932
Echinococcus granulosus tyrosine protein kinase ABL1 0.0143 0.0082 0.0073
Brugia malayi Immunoglobulin I-set domain containing protein 0.0421 0.08 0.078
Giardia lamblia Kinase, CAMK CAMKL 0.0187 0.0196 0.0599
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0335 0.0577 0.0577
Trichomonas vaginalis AGC family protein kinase 0.0257 0.0376 0.1148
Echinococcus granulosus roundabout 2 0.114 0.2656 0.265
Loa Loa (eye worm) hypothetical protein 0.0171 0.0155 0.0145
Entamoeba histolytica serine/threonine protein kinase, putative 0.0171 0.0155 0.077
Schistosoma mansoni protein kinase 0.0218 0.0277 0.0277
Echinococcus granulosus tyrosine kinase 0.0143 0.0082 0.0073
Echinococcus multilocularis activin receptor type 0.0144 0.0083 0.0075
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0144 0.0083 0.0083
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0766 0.1691 0.797
Giardia lamblia Kinase, CK1 Casein kinase 0.0237 0.0325 0.099
Onchocerca volvulus 0.0182 0.0183 0.0759
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1074 0.2486 0.2479
Loa Loa (eye worm) SRC-1 0.0333 0.0573 0.0563
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0481 0.0955 0.0947
Schistosoma mansoni protein kinase C mu 0.0473 0.0935 0.0935
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0185 0.019 0.0946
Echinococcus multilocularis serine:threonine protein kinase N2 0.0351 0.0618 0.061
Trichomonas vaginalis CK1 family protein kinase 0.0237 0.0325 0.099
Trypanosoma cruzi cdc2-related kinase 3 0.0259 0.0381 0.0381
Entamoeba histolytica disulphide oxidoreductase, putative 0.0366 0.0659 0.3279
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.012 0.0022 0.0067
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0395 0.0734 0.0726
Entamoeba histolytica p21-activated kinase 0.0204 0.024 0.1196
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.138 0.3277 0.3277
Giardia lamblia Kinase, CMGC GSK 0.028 0.0437 0.1333
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0183 0.0174
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0366 0.0659 0.0659
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0699 0.1518 0.151
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0366 0.0659 0.2004
Echinococcus granulosus cyclin dependent kinase 1 0.0259 0.0381 0.0373
Schistosoma mansoni protein kinase 0.0942 0.2147 0.2147
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0335 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Schistosoma mansoni g1/s-specific cyclin C 0.1753 0.424 0.424
Entamoeba histolytica protein kinase domain containing protein 0.0257 0.0376 0.1872
Entamoeba histolytica protein kinase, putative 0.0635 0.1354 0.6736
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0315 0.0527 0.0518
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0335 0.0577 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0155 0.0155
Leishmania major dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.1036 0.2388 0.2388
Loa Loa (eye worm) hypothetical protein 0.0143 0.0082 0.0072
Brugia malayi EGF-like domain containing protein 0.0402 0.0752 0.0732
Entamoeba histolytica PH domain containing protein kinase, putative 0.0263 0.0392 0.1949
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0421 0.08 0.0792
Schistosoma mansoni serine/threonine protein kinase 0.0437 0.0841 0.0841
Echinococcus multilocularis roundabout 2 0.0421 0.08 0.0792
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0266 0.0401 0.0401
Schistosoma mansoni protein kinase 0.0237 0.0325 0.0325
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Echinococcus granulosus rho-associated protein kinase 1 0.0707 0.1537 0.153
Schistosoma mansoni vesicular amine transporter 0.0718 0.1568 0.1568
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1686 0.4066 0.4061
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0194 0.0214 0.0204
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0297 0.0479 0.0479
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0183 0.0185 0.0185
Echinococcus granulosus epidermal growth factor receptor 0.0528 0.1075 0.1068
Loa Loa (eye worm) TK/ALK protein kinase 0.0332 0.057 0.0561
Entamoeba histolytica protein kinase, putative 0.0141 0.0076 0.0379
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.138 0.3277 1
Entamoeba histolytica protein kinase, putative 0.0223 0.0288 0.1433
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0219 0.0278 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Schistosoma mansoni notch 0.0402 0.0752 0.0752
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0494 0.0494
Schistosoma mansoni nck2/grb4 0.0134 0.0058 0.0058
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0588 0.123 0.1223
Trichomonas vaginalis CAMK family protein kinase 0.0604 0.1272 0.3881
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Onchocerca volvulus 0.0143 0.0082 0.0273
Brugia malayi Protein kinase domain containing protein 0.1182 0.2767 0.2751
Entamoeba histolytica protein kinase, putative 0.0145 0.0086 0.043
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0366 0.0659 0.0651
Onchocerca volvulus 0.0143 0.0082 0.0273
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0163 0.0133 0.0123
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0366 0.0659 0.0651
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0182 0.0183 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0395 0.0734 0.0726
Brugia malayi Protein kinase domain containing protein 0.0797 0.1771 0.1753
Echinococcus multilocularis cyclin dependent kinase 5 0.0259 0.0381 0.0373
Brugia malayi Temporarily assigned gene name protein 59 0.0242 0.0339 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0181 0.0181
Echinococcus granulosus lachesin 0.0401 0.0749 0.0741
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0183 0.0185 0.0175
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0366 0.0659 0.0659
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0219 0.0278 0.0278
Trypanosoma cruzi cdc2-related kinase 1 0.0259 0.0381 0.0381
Schistosoma mansoni titin 0.0182 0.0183 0.0183
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0259 0.0381 0.0372
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0259 0.0381 0.0381
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Giardia lamblia High cysteine protein 0.0402 0.0752 0.2294
Loa Loa (eye worm) cyclin C 0.1753 0.424 0.4234
Leishmania major acetoin dehydrogenase e3 component-like protein 0.138 0.3277 0.3277
Toxoplasma gondii CMGC kinase, CK2 family 0.0218 0.0277 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0937 0.2134 0.2126
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0351 0.0618 0.061
Echinococcus granulosus Immunoglobulin subtype 0.0219 0.0278 0.027
Brugia malayi hypothetical protein 0.0219 0.0278 0.0257
Loa Loa (eye worm) hypothetical protein 0.0246 0.0349 0.034
Onchocerca volvulus 0.0401 0.0747 0.3455
Trichomonas vaginalis CK1 family protein kinase 0.0237 0.0325 0.099
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0366 0.0659 0.201
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Echinococcus multilocularis dual specificity 0.0303 0.0494 0.0486
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0366 0.0659 0.0659
Echinococcus granulosus serine:threonine protein kinase MARK2 0.047 0.0926 0.0918
Brugia malayi Protein kinase domain containing protein 0.0143 0.0082 0.006
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0183 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0401 0.0749 0.074
Brugia malayi protein kinase C3,putative 0.0343 0.0599 0.0579
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0257 0.0376 0.1872
Giardia lamblia Aurora kinase 0.0257 0.0376 0.1148
Echinococcus granulosus tyrosine protein kinase Srms 0.0593 0.1245 0.1237
Echinococcus multilocularis notch 0.0402 0.0752 0.0744
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0357 0.0635 0.0627
Brugia malayi Protein kinase domain containing protein 0.0637 0.1357 0.1338
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0383 0.0701 0.0692
Schistosoma mansoni tyrosine kinase 0.0139 0.0071 0.0071
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0402 0.0752 0.3479
Entamoeba histolytica protein kinase, putative 0.0303 0.0494 0.2461
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.022 0.0281 0.0259
Schistosoma mansoni titin 0.0202 0.0235 0.0235
Echinococcus granulosus calcium activated potassium channel 0.0294 0.0471 0.0463
Brugia malayi serine/threonine protein kinase 6 0.0257 0.0376 0.0355
Loa Loa (eye worm) hypothetical protein 0.0221 0.0283 0.0274
Onchocerca volvulus 0.0182 0.0183 0.0759
Plasmodium falciparum protein serine/threonine kinase-1 0.0335 0.0577 0.0577
Schistosoma mansoni hypothetical protein 0.0219 0.0278 0.0278
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0144 0.0083 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0022 0.0022
Echinococcus granulosus cyclin dependent kinase 9 0.0181 0.018 0.0172
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2044 0.4993 0.4988
Echinococcus multilocularis Immunoglobulin 0.0219 0.0278 0.027
Brugia malayi ephrin receptor 1 precursor 0.0136 0.0065 0.0043
Schistosoma mansoni ste20-related kinase 0.0446 0.0865 0.0865
Schistosoma mansoni septate junction protein 0.0401 0.0749 0.0749
Plasmodium vivax protein kinase Crk2 0.0259 0.0381 0.0381
Brugia malayi Animal haem peroxidase family protein 0.0182 0.0183 0.0162
Schistosoma mansoni serine/threonine kinase 0.0351 0.0618 0.0618
Schistosoma mansoni notch 0.0402 0.0752 0.0752
Echinococcus granulosus CDC7 cell division cycle 7 0.0196 0.0219 0.021
Echinococcus multilocularis down syndrome cell adhesion 0.0182 0.0183 0.0175
Echinococcus multilocularis protein kinase c epsilon type 0.0444 0.086 0.0852
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0231 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Brugia malayi Fes/CIP4 homology domain containing protein 0.0222 0.0286 0.0265
Echinococcus multilocularis Immunoglobulin 0.0219 0.0278 0.027
Echinococcus granulosus cyclin dependent kinase 5 0.0259 0.0381 0.0373
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0163 0.0133 0.0133
Brugia malayi Calcium binding EGF domain containing protein 0.0402 0.0752 0.0732
Entamoeba histolytica protein kinase, putative 0.0266 0.0401 0.1994
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0478 0.0947 0.0939
Entamoeba histolytica PH domain containing protein kinase, putative 0.0357 0.0636 0.3165
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0441 0.0851 0.0843
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1182 0.2767 0.276
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0333 0.0573 0.0565
Echinococcus granulosus roundabout 2 0.0421 0.08 0.0792
Brugia malayi casein kinase I 0.0237 0.0325 0.0303
Schistosoma mansoni titin 0.0182 0.0183 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Loa Loa (eye worm) TK protein kinase 0.0271 0.0413 0.0404
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.138 0.3277 0.2803
Echinococcus granulosus contactin 0.0421 0.08 0.0792
Schistosoma mansoni glutamate synthase 0.0366 0.0659 0.0659
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0185 0.0564
Echinococcus granulosus neurogenic locus notch protein 0.0402 0.0752 0.0744
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.012 0.0022 0.0012
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0165 0.0138 0.0129
Toxoplasma gondii NADPH-glutathione reductase 0.138 0.3277 0.3277
Loa Loa (eye worm) TK protein kinase 0.0336 0.058 0.057
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0009 0.0009
Onchocerca volvulus 0.0402 0.0752 0.3479
Trypanosoma cruzi NADH dehydrogenase, putative 0.0366 0.0659 0.0659
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0366 0.0659 0.201
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1587 0.3812 0.3807
Loa Loa (eye worm) hypothetical protein 0.0524 0.1066 0.1057
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.138 0.3277 0.3277
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0357 0.0633 0.0624
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0194 0.0214 0.0653
Brugia malayi Protein kinase domain containing protein 0.0472 0.0931 0.0911
Echinococcus multilocularis rho associated protein kinase 0.0707 0.1537 0.153
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0134 0.0058 0.0058
Echinococcus multilocularis protein kinase c iota type 0.0621 0.1317 0.131
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Brugia malayi protein unc-22 0.0275 0.0422 0.0401
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Echinococcus multilocularis insulin growth factor binding 0.0182 0.0183 0.0175
Trypanosoma cruzi NADH dehydrogenase, putative 0.0366 0.0659 0.0659
Onchocerca volvulus 0.0743 0.1632 0.7686
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0381 0.1164
Loa Loa (eye worm) hypothetical protein 0.0134 0.0058 0.0048
Trichomonas vaginalis STE family protein kinase 0.0188 0.0198 0.0603
Loa Loa (eye worm) hypothetical protein 0.0202 0.0235 0.0225
Giardia lamblia Kinase, STE STE20 0.0188 0.0198 0.0603
Schistosoma mansoni serine/threonine protein kinase 0.0856 0.1924 0.1924
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0185 0.0564
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0246 0.0349 0.0349
Echinococcus granulosus casein kinase I gamma 0.0464 0.0911 0.0903
Schistosoma mansoni netrin receptor unc5 0.0219 0.0278 0.0278
Onchocerca volvulus 0.031 0.0513 0.2335
Entamoeba histolytica protein kinase 2, putative 0.0341 0.0593 0.2953
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0766 0.1691 0.1684
Schistosoma mansoni atypical protein kinase C 0.0634 0.1351 0.1351
Schistosoma mansoni glutamate synthase 0.0366 0.0659 0.0659
Brugia malayi Protein kinase domain containing protein 0.0135 0.0062 0.0041
Echinococcus multilocularis expressed conserved protein 0.0185 0.019 0.0182
Loa Loa (eye worm) cyclin domain-containing protein 0.0877 0.1977 0.1969
Echinococcus granulosus Immunoglobulin 0.0219 0.0278 0.027
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0333 0.0573 0.0565
Plasmodium vivax casein kinase 1, putative 0.0237 0.0325 0.0325
Onchocerca volvulus 0.0743 0.1632 0.7686
Echinococcus granulosus epidermal growth factor receptor 0.0758 0.1669 0.1662
Echinococcus granulosus tyrosine protein kinase Src64B 0.0333 0.0573 0.0565
Giardia lamblia NADH oxidase lateral transfer candidate 0.138 0.3277 1
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0366 0.0659 0.0651
Echinococcus granulosus activin receptor type 0.0144 0.0083 0.0075
Echinococcus granulosus casein kinase I alpha 0.0237 0.0325 0.0316
Brugia malayi EGF-like domain containing protein 0.0402 0.0752 0.0732
Onchocerca volvulus 0.0139 0.0071 0.0224
Brugia malayi pregnancy-associated plasma protein-A 0.0743 0.1632 0.1613
Trichomonas vaginalis CK1 family protein kinase 0.0237 0.0325 0.099
Echinococcus granulosus thioredoxin glutathione reductase 0.3983 1 1
Onchocerca volvulus 0.0743 0.1632 0.7686
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.123 0.123
Echinococcus granulosus titin 0.0182 0.0183 0.0175
Brugia malayi Protein kinase domain containing protein 0.0266 0.0401 0.038
Loa Loa (eye worm) hypothetical protein 0.0401 0.0749 0.074
Schistosoma mansoni tyrosine kinase 0.0205 0.0241 0.0241
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0185 0.019 0.0946
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0472 0.0931 0.0923
Brugia malayi Doublecortin family protein 0.0328 0.0561 0.054
Brugia malayi Immunoglobulin I-set domain containing protein 0.022 0.028 0.0258
Brugia malayi EGF-like domain containing protein 0.0402 0.0752 0.0732
Echinococcus multilocularis cyclin dependent kinase 1 0.0259 0.0381 0.0373
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0178 0.0172 0.0164
Echinococcus granulosus dual specificity 0.0303 0.0494 0.0486
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0188 0.0198 0.0189
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.138 0.3277 1
Trypanosoma cruzi casein kinase, putative 0.0237 0.0325 0.0325
Trichomonas vaginalis AGC family protein kinase 0.0178 0.0172 0.0526
Loa Loa (eye worm) hypothetical protein 0.0139 0.0071 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0766 0.1691 0.1691
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.138 0.3277 0.3277
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0401 0.0749 0.0741
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0366 0.0659 0.0651
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0155 0.0155
Brugia malayi Protein kinase domain containing protein 0.0635 0.1354 0.1335
Schistosoma mansoni hypothetical protein 0.0242 0.0339 0.0339
Loa Loa (eye worm) hypothetical protein 0.0194 0.0213 0.0203
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0182 0.0183 0.0183
Schistosoma mansoni tyrosine kinase 0.0654 0.1403 0.1403
Schistosoma mansoni protein kinase 0.0419 0.0796 0.0796
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0278 0.043 0.0421
Brugia malayi Casein kinase II, alpha chain 0.0218 0.0277 0.0255
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.1014 0.2331 0.2314
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Echinococcus granulosus serine:threonine protein kinase N2 0.0632 0.1345 0.1337
Trypanosoma brucei rac serine-threonine kinase, putative 0.0635 0.1354 0.1354
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0483 0.0961 0.0953
Echinococcus multilocularis dual specificity 0.0303 0.0494 0.0486
Loa Loa (eye worm) hypothetical protein 0.0235 0.032 0.031
Loa Loa (eye worm) AGC/PKA protein kinase 0.0246 0.0349 0.034
Loa Loa (eye worm) AGC/AKT protein kinase 0.0635 0.1354 0.1345
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0325 0.0325
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0437 0.084 0.0833
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0235 0.0213
Trichomonas vaginalis STE family protein kinase 0.0188 0.0198 0.0603
Schistosoma mansoni serine/threonine kinase 0.0488 0.0973 0.0973
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0278 0.043 0.0421
Loa Loa (eye worm) hypothetical protein 0.0186 0.0194 0.0184
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Brugia malayi Myb-like DNA-binding domain containing protein 0.0182 0.0183 0.0162
Loa Loa (eye worm) hypothetical protein 0.0738 0.162 0.1611
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0402 0.0752 0.0752
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.138 0.3277 0.3277
Trichomonas vaginalis CMGC family protein kinase 0.0196 0.0219 0.0667
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Plasmodium falciparum protein kinase 5 0.0259 0.0381 0.0381
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0183 0.0185 0.0176
Plasmodium falciparum NIMA related kinase 1 0.0297 0.0479 0.0479
Schistosoma mansoni rap gtpase-activating protein 0.0242 0.0339 0.0339
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0218 0.0277 0.0277
Echinococcus granulosus casein kinase I delta 0.0237 0.0325 0.0316
Plasmodium vivax serine/threonine kinase-1, putative 0.0335 0.0577 0.0577
Echinococcus granulosus tyrosine protein kinase Src42A 0.0203 0.0236 0.0227
Loa Loa (eye worm) animal heme peroxidase 0.0182 0.0183 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0441 0.0851 0.0851
Entamoeba histolytica hypothetical protein 0.042 0.0797 0.3966
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0278 0.043 0.042
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.138 0.3277 0.3277
Loa Loa (eye worm) hypothetical protein 0.0401 0.0749 0.074
Echinococcus granulosus basement membrane specific heparan sulfate 0.0219 0.0278 0.027
Echinococcus multilocularis fat cadherin tumor suppressor 0.0402 0.0752 0.0744
Echinococcus multilocularis casein kinase ii subunit alpha 0.0218 0.0277 0.0268
Schistosoma mansoni myosin-binding protein-related 0.0202 0.0235 0.0235
Schistosoma mansoni basigin related 0.0219 0.0278 0.0278
Brugia malayi cyclin-dependent kinase 9 0.0165 0.0138 0.0117
Echinococcus multilocularis tyrosine protein kinase otk 0.0401 0.0749 0.0741
Trichomonas vaginalis CAMK family protein kinase 0.0588 0.123 0.3753
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1032 0.1032
Loa Loa (eye worm) hypothetical protein 0.0258 0.0379 0.037
Brugia malayi hypothetical protein 0.0242 0.0339 0.0317
Echinococcus granulosus serine threonine protein kinase nrc 0.0341 0.0593 0.0585
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0333 0.0573 0.0565
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0246 0.0349 0.0349
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0351 0.0618 0.061
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.022 0.0281 0.0273
Loa Loa (eye worm) hypothetical protein 0.112 0.2605 0.2597
Echinococcus granulosus notch 0.0402 0.0752 0.0744
Brugia malayi EGF-like domain containing protein 0.0451 0.0877 0.0857
Brugia malayi SH2 domain containing protein 0.0478 0.0947 0.0927
Echinococcus multilocularis mitogen activated protein kinase 3 0.0183 0.0185 0.0177
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0937 0.2134 0.2127
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0471 0.0471
Brugia malayi Immunoglobulin I-set domain containing protein 0.0738 0.162 0.1601
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Brugia malayi Calcium binding EGF domain containing protein 0.0402 0.0752 0.0732
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0182 0.0181 0.0172
Brugia malayi Thioredoxin reductase 0.3983 1 1
Plasmodium falciparum protein kinase, putative 0.0144 0.0083 0.0083
Schistosoma mansoni sulfide quinone reductase 0.0366 0.0659 0.0659
Echinococcus granulosus titin 0.0275 0.0422 0.0414
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0187 0.0196 0.0196
Trypanosoma brucei polo-like protein kinase 0.0588 0.123 0.123
Loa Loa (eye worm) disorganized muscle protein 1 0.0182 0.0183 0.0174
Schistosoma mansoni protein kinase 0.0188 0.0198 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0494 0.1509
Schistosoma mansoni nephrin related 0.0219 0.0278 0.0278
Brugia malayi basement membrane proteoglycan 0.0219 0.0278 0.0257
Schistosoma mansoni titin 0.0275 0.0422 0.0422
Brugia malayi Immunoglobulin I-set domain containing protein 0.0401 0.0749 0.0729
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0257 0.0376 0.1872
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Schistosoma mansoni tyrosine kinase 0.0528 0.1075 0.1075
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Entamoeba histolytica protein kinase domain containing protein 0.0441 0.0851 0.4236
Brugia malayi Protein kinase domain containing protein 0.0143 0.0082 0.006
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Entamoeba histolytica protein kinase , putative 0.0257 0.0376 0.1872
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0797 0.1771 0.1764
Mycobacterium ulcerans NADH dehydrogenase 0.0366 0.0659 0.2004
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0395 0.0734 0.0726
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0246 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0194 0.0213 0.0203
Brugia malayi EGF-like domain containing protein 0.0402 0.0752 0.0732
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Echinococcus granulosus neural cadherin 0.0402 0.0752 0.0744
Echinococcus multilocularis 0.0182 0.0183 0.0175
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.138 0.3277 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0246 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.022 0.0281 0.0271
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0257 0.0376 0.1872
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0333 0.0573 0.0565
Echinococcus multilocularis serine:threonine protein kinase 0.0249 0.0355 0.0347
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0366 0.0659 0.201
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.022 0.0281 0.0273
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0278 0.043 0.0409
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0177 0.017 0.017
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0366 0.0659 0.0651
Trichomonas vaginalis glutamate synthase, putative 0.0366 0.0659 0.201
Echinococcus granulosus growth factor receptor bound protein 2 0.0136 0.0064 0.0055
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0366 0.0659 0.2004
Loa Loa (eye worm) hypothetical protein 0.0743 0.1632 0.1624
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0237 0.0325 0.0325
Loa Loa (eye worm) TK/ROR protein kinase 0.0253 0.0366 0.0357
Entamoeba histolytica protein kinase, putative 0.0178 0.0172 0.0858
Echinococcus granulosus protein tyrosine kinase 0.063 0.1339 0.1332
Loa Loa (eye worm) CMGC/GSK protein kinase 0.028 0.0437 0.0427
Schistosoma mansoni protein kinase 0.0942 0.2147 0.2147
Onchocerca volvulus Neurogenic locus notch homolog 0.0402 0.0752 0.3479
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0174 0.0161 0.0153
Trypanosoma brucei protein kinase, putative 0.0144 0.0083 0.0083
Schistosoma mansoni cell adhesion molecule 0.0219 0.0278 0.0278
Trypanosoma brucei aurora B kinase 0.0257 0.0376 0.0376
Trichomonas vaginalis CMGC family protein kinase 0.0218 0.0277 0.0844
Trypanosoma brucei protein kinase, putative 0.0199 0.0227 0.0227
Echinococcus multilocularis slit 2 protein 0.0451 0.0877 0.0869
Echinococcus granulosus NCK adaptor protein 0.0134 0.0058 0.005
Echinococcus granulosus glycogen synthase kinase 3 beta 0.028 0.0437 0.0429
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0219 0.0278 0.027
Entamoeba histolytica protein kinase domain containing protein 0.0165 0.0138 0.0689
Onchocerca volvulus 0.0677 0.1462 0.6874
Brugia malayi Immunoglobulin I-set domain containing protein 0.0275 0.0422 0.0401
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0437 0.0841 0.0832
Plasmodium falciparum calcium-dependent protein kinase 1 0.022 0.0281 0.0281
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0511 0.1032 0.1025
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0381 0.0381
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0303 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Schistosoma mansoni tyrosine kinase 0.0654 0.1403 0.1403
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0259 0.0381 0.0381
Plasmodium falciparum calcium-dependent protein kinase 2 0.022 0.0281 0.0281
Brugia malayi Immunoglobulin I-set domain containing protein 0.1686 0.4066 0.4053
Brugia malayi Variant SH3 domain containing protein 0.0134 0.0058 0.0036
Schistosoma mansoni protein kinase 0.0481 0.0955 0.0955
Echinococcus granulosus defective proboscis extension response 0.0718 0.1568 0.1561
Echinococcus multilocularis neurogenic locus protein delta 0.0402 0.0752 0.0744
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0444 0.086 0.0851
Loa Loa (eye worm) thioredoxin reductase 0.3983 1 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.022 0.0281 0.0273
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.022 0.0281 0.0271
Loa Loa (eye worm) AGC/PKN protein kinase 0.0632 0.1345 0.1336
Entamoeba histolytica protein kinase, putative 0.022 0.0281 0.1398
Echinococcus multilocularis NCK adaptor protein 0.0136 0.0064 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0381 0.0381
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus granulosus NDR protein kinase 0.0351 0.0618 0.061
Schistosoma mansoni peroxidasin 0.022 0.028 0.028
Echinococcus granulosus protein jagged 2 0.0402 0.0752 0.0744
Schistosoma mansoni hypothetical protein 0.0202 0.0235 0.0235
Leishmania major casein kinase, putative 0.0237 0.0325 0.0325
Entamoeba histolytica protein kinase, putative 0.0635 0.1354 0.6736
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0235 0.0225
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0328 0.0561 0.0552
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0722 0.1579 0.157
Echinococcus multilocularis tyrosine protein kinase HCK 0.0199 0.0227 0.0219
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0333 0.0573 0.0565
Trichomonas vaginalis CMGC family protein kinase 0.0303 0.0494 0.1509
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0341 0.0593 0.0593
Loa Loa (eye worm) hypothetical protein 0.0401 0.0749 0.074
Onchocerca volvulus 0.0202 0.0235 0.1004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0231 0.0308 0.0287
Brugia malayi Protein kinase domain containing protein 0.0766 0.1691 0.1673
Trypanosoma cruzi hypothetical protein, conserved 0.0366 0.0659 0.0659
Echinococcus multilocularis netrin receptor unc 5 0.0282 0.044 0.0432
Trypanosoma brucei SNF1-related protein kinases, putative 0.0171 0.0155 0.0155
Brugia malayi serine/threonine-protein kinase plk-2 0.0588 0.123 0.1211
Loa Loa (eye worm) projectin 0.0202 0.0235 0.0225
Echinococcus multilocularis cyclin dependent kinase 0.0259 0.0381 0.0373
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.0424 0.1293
Brugia malayi kettin 0.0182 0.0183 0.0162
Brugia malayi putative serine/threonine kinase SADA gamma 0.0171 0.0155 0.0133
Loa Loa (eye worm) AUR protein kinase 0.0257 0.0376 0.0367
Trypanosoma cruzi polo-like protein kinase, putative 0.0588 0.123 0.123
Schistosoma mansoni notch 0.0402 0.0752 0.0752
Echinococcus granulosus aurora kinase A 0.0257 0.0376 0.0368
Echinococcus granulosus dual specificity 0.0266 0.0401 0.0393
Entamoeba histolytica PH domain containing protein kinase, putative 0.0263 0.0392 0.1949
Loa Loa (eye worm) hypothetical protein 0.023 0.0306 0.0297
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0237 0.0325 0.0315
Entamoeba histolytica protein kinase, putative 0.0257 0.0376 0.1872
Echinococcus granulosus cyclin dependent kinase 19 0.1182 0.2767 0.2761
Brugia malayi SH2 domain containing protein 0.0143 0.0082 0.006
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0183 0.0174
Giardia lamblia Kinase, AGC AKT 0.0255 0.0372 0.1134
Trypanosoma cruzi casein kinase, putative 0.0237 0.0325 0.0325
Echinococcus granulosus mitogen activated protein kinase 0.0183 0.0185 0.0177
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0235 0.0225
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0272 0.0414 0.0414
Echinococcus multilocularis mitogen activated protein kinase 14 0.0346 0.0607 0.0599
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0349 0.0349
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0188 0.0198 0.0189
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0185 0.019 0.019
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0182 0.0183 0.0175
Echinococcus granulosus netrin receptor unc 5 0.0282 0.044 0.0432
Loa Loa (eye worm) hypothetical protein 0.031 0.0513 0.0504
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0266 0.0401 0.0401
Schistosoma mansoni basigin related 0.0219 0.0278 0.0278
Trichomonas vaginalis STE family protein kinase 0.0297 0.0479 0.146
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0366 0.0659 0.0659
Brugia malayi Protein kinase domain containing protein 0.0654 0.1403 0.1384
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0942 0.2147 0.214
Schistosoma mansoni tyrosine kinase 0.0307 0.0505 0.0505
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0366 0.0659 0.2004
Echinococcus granulosus casein kinase I alpha 0.0237 0.0325 0.0316
Echinococcus multilocularis tyrosine protein kinase 0.0336 0.058 0.0572
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0235 0.0213
Echinococcus granulosus slit 2 protein 0.0451 0.0877 0.0869
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0797 0.1771 0.1763
Leishmania major protein kinase A catalytic subunit 0.0246 0.0349 0.0349
Entamoeba histolytica casein kinase, putative 0.0218 0.0277 0.1377
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0366 0.0659 0.0638
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0335 0.0577 0.0567
Echinococcus multilocularis Immunoglobulin 0.0718 0.1568 0.1561
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.138 0.3277 0.3277
Echinococcus granulosus tyrosine protein kinase 0.0336 0.058 0.0572
Echinococcus multilocularis fibropellin Ia 0.0402 0.0752 0.0744
Echinococcus granulosus dual specificity 0.0303 0.0494 0.0486
Brugia malayi Kinase associated domain 1 family protein 0.0221 0.0283 0.0262
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0736 0.1613 0.1604
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0473 0.0935 0.0915
Schistosoma mansoni netrin receptor unc5 0.0282 0.044 0.044
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0315 0.0527 0.0519
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0183 0.0185 0.0185
Schistosoma mansoni notch 0.0402 0.0752 0.0752
Echinococcus multilocularis hypothetical protein 0.0221 0.0283 0.0275
Echinococcus multilocularis growth factor receptor bound protein 2 0.0134 0.0058 0.005
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0699 0.1518 0.151
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0494 0.0988 0.0979
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0115 0.0009 0.0000043283
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0182 0.0181 0.0181
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0242 0.0339 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.043 0.043
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Trichomonas vaginalis CAMK family protein kinase 0.0472 0.0931 0.2842
Echinococcus granulosus cGMP dependent protein kinase 1 0.0185 0.019 0.0182
Trypanosoma cruzi casein kinase II, putative 0.0218 0.0277 0.0277
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0877 0.1977 0.197
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0203 0.0236 0.0227
Brugia malayi Protein kinase domain containing protein 0.0351 0.0618 0.0597
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0251 0.0361 0.0352
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0219 0.0278 0.0278
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0366 0.0659 0.0651
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0341 0.0593 0.0585
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0251 0.0361 0.0352
Echinococcus granulosus insulin receptor 0.0654 0.1403 0.1396
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0718 0.1568 0.1568
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0503 0.1012 0.1004
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0346 0.0607 0.0607
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Echinococcus granulosus casein kinase I delta 0.0237 0.0325 0.0316
Mycobacterium tuberculosis Probable oxidoreductase 0.138 0.3277 0.2803
Plasmodium falciparum ferrodoxin reductase-like protein 0.0366 0.0659 0.0659
Brugia malayi Immunoglobulin domain containing protein 0.0219 0.0278 0.0257
Brugia malayi Protein kinase domain containing protein 0.0373 0.0677 0.0656
Loa Loa (eye worm) AUR protein kinase 0.0257 0.0376 0.0367
Onchocerca volvulus 0.0402 0.0752 0.3479
Echinococcus multilocularis PAK box P21 Rho binding 0.0141 0.0076 0.0068
Giardia lamblia Kinase, CMGC CK2 0.0218 0.0277 0.0844
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Schistosoma mansoni tyrosine kinase 0.0395 0.0734 0.0734
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Loa Loa (eye worm) hypothetical protein 0.0718 0.1568 0.156
Echinococcus multilocularis insulin receptor 0.0654 0.1403 0.1396
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.0618 0.0618
Trypanosoma brucei trypanothione reductase 0.3983 1 1
Schistosoma mansoni tyrosine kinase 0.0457 0.0892 0.0892
Loa Loa (eye worm) protein kinase domain-containing protein 0.0464 0.0911 0.0902
Echinococcus granulosus insulin growth factor binding 0.0182 0.0183 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0366 0.0659 0.065
Trypanosoma cruzi polo-like protein kinase, putative 0.0588 0.123 0.123
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0246 0.0349 0.0349
Echinococcus granulosus serine/threonine protein kinase 0.0357 0.0636 0.0628
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0183 0.0185 0.0185
Echinococcus multilocularis serine:threonine protein kinase N2 0.0281 0.0439 0.0431
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0219 0.0278 0.027
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.138 0.3277 0.3277
Schistosoma mansoni cell adhesion molecule 0.0421 0.08 0.08
Echinococcus multilocularis roundabout 2 0.0421 0.08 0.0792
Loa Loa (eye worm) TK/FER protein kinase 0.0478 0.0947 0.0938
Onchocerca volvulus 0.0242 0.0339 0.1502
Loa Loa (eye worm) hypothetical protein 0.0219 0.0278 0.0269
Echinococcus multilocularis casein kinase I gamma 0.0464 0.0911 0.0903
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0171 0.0155 0.0145
Echinococcus granulosus casein kinase i 0.0237 0.0325 0.0316
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0366 0.0659 0.0659
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0357 0.0635 0.0627
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0366 0.0659 0.0659
Plasmodium vivax thioredoxin reductase, putative 0.3983 1 1
Onchocerca volvulus 0.0196 0.0219 0.0929
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0268 0.0405 0.0397
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0185 0.019 0.0182
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0856 0.1924 0.1918
Leishmania major protein kinase, putative 0.0335 0.0577 0.0577
Echinococcus granulosus tyrosine protein kinase Blk 0.0271 0.0413 0.0405
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0335 0.0577 0.0577
Giardia lamblia Kinase, AGC PKA 0.0246 0.0349 0.1065
Onchocerca volvulus Serine\/threonine kinase homolog 0.0357 0.0635 0.292
Schistosoma mansoni cell adhesion molecule 0.0957 0.2185 0.2185
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.1014 0.2331 0.2314
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.028 0.0437 0.0437
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0421 0.08 0.0792
Loa Loa (eye worm) hypothetical protein 0.0249 0.0355 0.0346
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.0083 0.0415
Trypanosoma cruzi cdc2-related kinase 3 0.0259 0.0381 0.0381
Onchocerca volvulus 0.0237 0.0325 0.1435
Leishmania major hypothetical protein, conserved 0.0366 0.0659 0.0659
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0437 0.084 0.0833
Echinococcus granulosus expressed protein 0.0182 0.0181 0.0173
Echinococcus granulosus cGMP dependent protein kinase 1 0.0185 0.019 0.0182
Brugia malayi Cadherin domain containing protein 0.0402 0.0752 0.0732
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0366 0.0659 0.2004
Echinococcus granulosus dual specificity protein kinase clk2 0.0335 0.0577 0.0569
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.03 0.0489 0.1491
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0351 0.0618 0.061
Echinococcus multilocularis mitogen activated protein kinase 14 0.0346 0.0607 0.0599
Brugia malayi Prion-like- 0.0401 0.0749 0.0729
Loa Loa (eye worm) TK protein kinase 0.0406 0.0761 0.0752
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0257 0.0376 0.0376
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0528 0.1075 0.1068
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0333 0.0573 0.0565
Schistosoma mansoni vav2 0.0179 0.0175 0.0175
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0402 0.0752 0.0732
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0115 0.0009 0.0000043283
Onchocerca volvulus 0.0143 0.0082 0.0273
Schistosoma mansoni tyrosine kinase 0.0379 0.0691 0.0691
Brugia malayi Hr1 repeat family protein 0.0632 0.1345 0.1326
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Loa Loa (eye worm) hypothetical protein 0.0401 0.0747 0.0738
Plasmodium falciparum casein kinase 2, alpha subunit 0.0218 0.0277 0.0277
Loa Loa (eye worm) TK/ABL protein kinase 0.0143 0.0082 0.0072
Echinococcus granulosus C type lectin domian containing protein 0.0743 0.1632 0.1625
Plasmodium vivax tyrosine kinase-like protein, putative 0.0177 0.017 0.017
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0188 0.0198 0.0189
Schistosoma mansoni serine/threonine protein kinase 0.0335 0.0577 0.0577
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.138 0.3277 0.3272
Brugia malayi intracellular kinase 0.028 0.0437 0.0416
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.138 0.3277 1
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0246 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0417 0.079 0.0781
Mycobacterium ulcerans ferredoxin reductase 0.0366 0.0659 0.2004
Plasmodium vivax glycogen synthase kinase 3, putative 0.028 0.0437 0.0437
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0366 0.0659 0.0659
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0231 0.0308 0.0298
Giardia lamblia Kinase, CDC7 0.0196 0.0219 0.0667
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1074 0.2486 0.2479
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0188 0.0198 0.0189
Echinococcus multilocularis tyrosine protein kinase shark 0.0379 0.0691 0.0683
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0185 0.019 0.019
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0121 0.0025 0.0015
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0246 0.0349 0.0349
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0483 0.0961 0.0952
Echinococcus granulosus protein jagged 1 0.0402 0.0752 0.0744
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Toxoplasma gondii aurora kinase 0.0257 0.0376 0.0376
Toxoplasma gondii selenide, water dikinase 0.0366 0.0659 0.0659
Echinococcus granulosus cyclin dependent kinase 9 0.0165 0.0138 0.013
Entamoeba histolytica protein kinase, putative 0.0188 0.0198 0.0984
Brugia malayi Heparan sulfate 0.0219 0.0278 0.0257
Trichomonas vaginalis AGC family protein kinase 0.0373 0.0677 0.2064
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0366 0.0659 0.0638
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0421 0.08 0.0791
Schistosoma mansoni tyrosine kinase 0.0457 0.0892 0.0892
Schistosoma mansoni hypothetical protein 0.0182 0.0183 0.0183
Echinococcus granulosus dual specificity 0.0303 0.0494 0.0486
Brugia malayi Cam kinase protein 1 0.022 0.0281 0.0259
Trypanosoma brucei NADH dehydrogenase 0.0366 0.0659 0.0659
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0766 0.1691 0.1684
Echinococcus multilocularis cyclin dependent kinase 1 0.0259 0.0381 0.0373
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0366 0.0659 0.2004
Schistosoma mansoni serine/threonine protein kinase 0.053 0.1082 0.1082
Echinococcus granulosus serine:threonine protein kinase 0.0249 0.0355 0.0347
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0366 0.0659 0.3279
Echinococcus multilocularis tyrosine protein kinase Blk 0.0271 0.0413 0.0405
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Schistosoma mansoni serine/threonine protein kinase 0.1182 0.2767 0.2767
Entamoeba histolytica protein kinase domain containing protein 0.0218 0.0277 0.1377
Giardia lamblia Kinase, CMGC CDK 0.0259 0.0381 0.1164
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0171 0.0155 0.0155
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Schistosoma mansoni nephrin 0.0421 0.08 0.08
Onchocerca volvulus Tyrosine kinase homolog 0.093 0.2116 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0268 0.0405 0.0397
Echinococcus multilocularis serine:threonine protein kinase 38 0.0351 0.0618 0.061
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0366 0.0659 0.0638
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Echinococcus multilocularis 0.0333 0.0574 0.0566
Schistosoma mansoni neuroglian 0.0421 0.08 0.08
Echinococcus multilocularis hemicentin 1 0.0401 0.0749 0.0741
Trichomonas vaginalis glutamate synthase, putative 0.0366 0.0659 0.201
Onchocerca volvulus 0.0182 0.0183 0.0759
Giardia lamblia Kinase, CMGC CDK 0.0259 0.0381 0.1164
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0182 0.0183 0.0175
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0718 0.1568 0.1561
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0178 0.0172 0.0164
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.022 0.0281 0.0281
Schistosoma mansoni kinase 0.0628 0.1333 0.1333
Loa Loa (eye worm) hypothetical protein 0.1146 0.2671 0.2664
Brugia malayi Immunoglobulin I-set domain containing protein 0.0219 0.0278 0.0257
Echinococcus granulosus neuroglian 0.0421 0.08 0.0792
Mycobacterium ulcerans glutamate synthase subunit beta 0.0366 0.0659 0.2004
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0171 0.0155 0.0146
Giardia lamblia Glutamate synthase 0.0366 0.0659 0.201
Echinococcus granulosus tyrosine protein kinase Lyn 0.0406 0.0761 0.0753
Trypanosoma cruzi casein kinase, putative 0.0237 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.1001 0.2298 0.229
Schistosoma mansoni serine/threonine protein kinase 0.0707 0.1537 0.1537
Trichomonas vaginalis glutathione reductase, putative 0.138 0.3277 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0182 0.0183 0.0174
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0974 0.2229 0.2221
Loa Loa (eye worm) hypothetical protein 0.0587 0.1229 0.122
Echinococcus granulosus cGMP dependent protein kinase 0.0185 0.019 0.0182
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus granulosus down syndrome cell adhesion 0.0182 0.0183 0.0175
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0333 0.0573 0.0565
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.022 0.0281 0.0281
Leishmania major NADH dehydrogenase, putative 0.0366 0.0659 0.0659
Echinococcus granulosus titin 0.0275 0.0422 0.0414
Brugia malayi p70 ribosomal S6 kinase beta 0.0619 0.1311 0.1292
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0619 0.1311 0.1303
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0315 0.0527 0.0518
Brugia malayi Protein kinase domain containing protein 0.0143 0.0082 0.006
Echinococcus granulosus raf serine:threonine protein kinase 0.0162 0.013 0.0121
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0182 0.0183 0.0162
Trichomonas vaginalis STE family protein kinase 0.0188 0.0198 0.0603
Brugia malayi Variant SH3 domain containing protein 0.0163 0.0133 0.0111
Echinococcus multilocularis cyclin dependent kinase 9 0.0181 0.018 0.0172
Schistosoma mansoni cell adhesion molecule 0.0219 0.0278 0.0278
Brugia malayi Delta serrate ligand family protein 0.0402 0.0752 0.0732
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0271 0.0413 0.0405
Loa Loa (eye worm) TK/INSR protein kinase 0.0654 0.1403 0.1394
Echinococcus granulosus protein kinase c iota type 0.0621 0.1317 0.131
Schistosoma mansoni notch 0.0402 0.0752 0.0752
Schistosoma mansoni notch 0.0402 0.0752 0.0752
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0182 0.0181 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Schistosoma mansoni serine/threonine protein kinase 0.0533 0.1089 0.1089
Echinococcus multilocularis death associated protein kinase 1 0.0973 0.2227 0.222
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0185 0.019 0.019
Echinococcus granulosus delta-like protein 1 0.0402 0.0752 0.0744
Brugia malayi Sex muscle abnormal protein 5 0.0134 0.0058 0.0036
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0366 0.0659 0.3279
Trichomonas vaginalis AGC family protein kinase 0.0297 0.0479 0.146
Trichomonas vaginalis CAMK family protein kinase 0.0249 0.0355 0.1084
Brugia malayi Protein kinase domain containing protein 0.0357 0.0635 0.0615
Schistosoma mansoni tyrosine kinase 0.044 0.0848 0.0848
Plasmodium falciparum thioredoxin reductase 0.138 0.3277 0.3277
Echinococcus multilocularis casein kinase i 0.0237 0.0325 0.0316
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0164 0.0137 0.0137
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Brugia malayi Immunoglobulin I-set domain containing protein 0.0421 0.08 0.078
Echinococcus multilocularis raf serine:threonine protein kinase 0.0162 0.013 0.0121
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.0424 0.1293
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0246 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0718 0.1568 0.156
Echinococcus multilocularis Protein kinase C, brain isozyme 0.053 0.1082 0.1074
Echinococcus granulosus c4b binding protein beta chain 0.0743 0.1632 0.1625
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.138 0.3277 0.3277
Onchocerca volvulus 0.0743 0.1632 0.7686
Onchocerca volvulus Slit protein homolog 0.0451 0.0877 0.4075
Giardia lamblia Kinase, CMGC DYRK 0.0303 0.0494 0.1509
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0366 0.0659 0.201
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0171 0.0155 0.0155
Echinococcus multilocularis c4b binding protein beta chain 0.0743 0.1632 0.1625
Trichomonas vaginalis STE family protein kinase 0.0188 0.0198 0.0603
Plasmodium falciparum serine/threonine protein kinase 0.0182 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0402 0.075 0.0741
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0237 0.0325 0.0315
Echinococcus granulosus protein kinase shaggy 0.028 0.0437 0.0429
Brugia malayi Immunoglobulin I-set domain containing protein 0.0182 0.0183 0.0162
Onchocerca volvulus 0.0143 0.0082 0.0273
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Echinococcus multilocularis calcium activated potassium channel 0.0294 0.0471 0.0463
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.022 0.0281 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0588 0.123 0.3753
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0143 0.0082 0.0073
Onchocerca volvulus 0.0634 0.135 0.6336
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.0618 0.0618
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0366 0.0659 0.201
Onchocerca volvulus 0.0139 0.0071 0.0223
Brugia malayi Protein kinase domain containing protein 0.0196 0.0219 0.0197
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0366 0.0659 0.0659
Schistosoma mansoni serine/threonine protein kinase 0.047 0.0926 0.0926
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0333 0.0573 0.0565
Schistosoma mansoni serine/threonine protein kinase 0.047 0.0926 0.0926
Echinococcus granulosus protein kinase C gamma type 0.0439 0.0847 0.084
Schistosoma mansoni hypothetical protein 0.0366 0.0659 0.0659
Plasmodium falciparum calcium-dependent protein kinase 5 0.022 0.0281 0.0281
Brugia malayi map kinase activated protein kinase protein 2 0.0856 0.1924 0.1907
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0162 0.013 0.012
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0401 0.0749 0.074
Echinococcus multilocularis neuroglian 0.0901 0.2039 0.2032
Entamoeba histolytica protein kinase, putative 0.0157 0.0119 0.0591
Echinococcus multilocularis roundabout 2 0.114 0.2656 0.265
Brugia malayi Immunoglobulin domain containing protein 0.0219 0.0278 0.0257
Entamoeba histolytica casein kinase 1, putative 0.0237 0.0325 0.1616
Brugia malayi Protein kinase domain containing protein 0.0974 0.2229 0.2212
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0257 0.0376 0.0368
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0346 0.0607 0.0607
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Schistosoma mansoni septate junction protein 0.0219 0.0278 0.0278
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0856 0.1924 0.1918
Echinococcus multilocularis protein jagged 1 0.0402 0.0752 0.0744
Onchocerca volvulus Peroxidasin homolog 0.0182 0.0183 0.0759
Echinococcus granulosus protein kinase 0.0333 0.0574 0.0566
Brugia malayi Prion-like- 0.0182 0.0183 0.0162
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0437 0.1333
Onchocerca volvulus 0.0202 0.0235 0.1004
Entamoeba histolytica protein kinase, putative 0.0182 0.0181 0.0903
Giardia lamblia Kinase, STE STE20 0.0185 0.019 0.058
Brugia malayi Temporarily assigned gene name protein 59 0.028 0.0435 0.0414
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0143 0.0082 0.0406
Loa Loa (eye worm) thyroid receptor interactor 0.0222 0.0286 0.0276
Echinococcus granulosus hypothetical protein 0.0262 0.0389 0.0381
Entamoeba histolytica protein kinase, putative 0.0182 0.0181 0.0903
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0366 0.0659 0.0659
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0235 0.0213
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0171 0.0155 0.0155
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0674 0.1454 0.1447
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.138 0.3277 0.3277
Loa Loa (eye worm) hypothetical protein 0.0738 0.162 0.1611
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0219 0.0278 0.027
Mycobacterium ulcerans flavoprotein disulfide reductase 0.138 0.3277 1
Leishmania major protein kinase A catalytic subunit isoform 1 0.0246 0.0349 0.0349
Echinococcus multilocularis serine:threonine protein kinase 3 0.0558 0.1155 0.1147
Onchocerca volvulus 0.0743 0.1632 0.7686
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0001 0.0004
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0303 0.0494 0.0494
Loa Loa (eye worm) hypothetical protein 0.0407 0.0764 0.0755
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0219 0.0278 0.0278
Echinococcus multilocularis calcium dependent protein kinase 0.0147 0.0093 0.0084
Trypanosoma cruzi Protein kinase B 0.0357 0.0636 0.0636
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0144 0.0083 0.0083
Plasmodium falciparum casein kinase 1 0.0237 0.0325 0.0325
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.019 0.019
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.138 0.3277 0.3272
Brugia malayi Stress-activated protein kinase jnk-1 0.0574 0.1196 0.1177
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0218 0.0277 0.0267
Entamoeba histolytica serine/threonine protein kinase, putative 0.0588 0.123 0.6122
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.012 0.0022 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.138 0.3277 0.3277
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0144 0.0083 0.0083
Onchocerca volvulus 0.0743 0.1632 0.7686
Brugia malayi Protein kinase domain containing protein 0.0699 0.1518 0.1499
Brugia malayi RhoGAP domain containing protein 0.0163 0.0133 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0171 0.0155 0.0472
Echinococcus granulosus Protein kinase C brain isozyme 0.053 0.1082 0.1074
Echinococcus multilocularis ephrin type A receptor 4 A 0.021 0.0254 0.0246
Trichomonas vaginalis STE family protein kinase 0.0141 0.0076 0.0233
Echinococcus granulosus nervana 2 0.0268 0.0405 0.0397
Loa Loa (eye worm) hypothetical protein 0.0402 0.0752 0.0743
Mycobacterium ulcerans hypothetical protein 0.0366 0.0659 0.2004
Schistosoma mansoni protein kinase 0.0797 0.1771 0.1771
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0371 0.0371
Brugia malayi Immunoglobulin I-set domain containing protein 0.0401 0.0749 0.0729
Brugia malayi Immunoglobulin I-set domain containing protein 0.0401 0.0749 0.0729
Entamoeba histolytica protein kinase, putative 0.0619 0.1311 0.6525
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.012 0.0022 0.0022
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.138 0.3277 0.3277
Brugia malayi Protein kinase domain containing protein 0.0249 0.0355 0.0334
Loa Loa (eye worm) TK/FAK protein kinase 0.0637 0.1357 0.1348
Trichomonas vaginalis CAMK family protein kinase 0.0588 0.123 0.3753
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0239 0.033 0.0321
Onchocerca volvulus 0.0743 0.1632 0.7686
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0766 0.1691 0.1673
Trichomonas vaginalis AGC family protein kinase 0.0257 0.0376 0.1148
Mycobacterium ulcerans dehydrogenase 0.0366 0.0659 0.2004
Schistosoma mansoni disulfide oxidoreductase 0.0366 0.0659 0.0659
Entamoeba histolytica cell division protein kinase 2, putative 0.0259 0.0381 0.1898
Leishmania major protein kinase, putative 0.022 0.0281 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0401 0.0401
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Brugia malayi basement membrane proteoglycan precursor 0.0219 0.0278 0.0257
Brugia malayi Protein kinase domain containing protein 0.0259 0.0381 0.036
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0022 0.0022
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0182 0.0181 0.0181
Schistosoma mansoni tyrosine kinase 0.0528 0.1075 0.1075
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0349 0.0349
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0351 0.0618 0.061
Trichomonas vaginalis CMGC family protein kinase 0.0183 0.0185 0.0564
Echinococcus multilocularis Immunoglobulin subtype 0.0219 0.0278 0.027
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Brugia malayi Protein kinase domain containing protein 0.0699 0.1518 0.1499
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0505 0.1016 0.1007
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.022 0.0281 0.0273
Echinococcus multilocularis aurora kinase A 0.0257 0.0376 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0554 0.1145 0.1145
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0588 0.123 0.1221
Brugia malayi Protein kinase c protein 2 0.0252 0.0364 0.0343
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0219 0.0278 0.027
Brugia malayi Immunoglobulin domain containing protein 0.0219 0.0278 0.0257
Trichomonas vaginalis CMGC family protein kinase 0.0196 0.0219 0.0667
Schistosoma mansoni slit 0.0183 0.0185 0.0185
Echinococcus multilocularis rac serine:threonine kinase 0.0357 0.0636 0.0628
Echinococcus granulosus hemicentin 1 0.0401 0.0749 0.0741
Entamoeba histolytica protein kinase, putative 0.0257 0.0376 0.1872
Brugia malayi Immunoglobulin I-set domain containing protein 0.0282 0.044 0.0419
Loa Loa (eye worm) hypothetical protein 0.0265 0.0397 0.0387
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0182 0.0181 0.0181
Leishmania major protein kinase A catalytic subunit isoform 2 0.0246 0.0349 0.0349
Schistosoma mansoni hemicentin 0.0202 0.0235 0.0235
Echinococcus multilocularis mitogen activated protein kinase 11 0.0346 0.0607 0.0599
Echinococcus granulosus casein kinase I alpha 0.0237 0.0325 0.0316
Schistosoma mansoni tyrosine kinase 0.0758 0.1669 0.1669
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0366 0.0659 0.3279
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Brugia malayi Protein kinase domain containing protein 0.0143 0.0082 0.006
Trypanosoma brucei Casein kinase II 0.0218 0.0277 0.0277
Leishmania major casein kinase II, putative 0.0218 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0242 0.0339 0.0329
Trypanosoma brucei protein kinase, putative 0.028 0.0437 0.0437
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0112 0.0001 0.0004
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0266 0.0401 0.0401
Echinococcus multilocularis protein jagged 1 0.0402 0.0752 0.0744
Loa Loa (eye worm) Notch2 0.0402 0.0752 0.0743
Loa Loa (eye worm) TK/FER protein kinase 0.0143 0.0082 0.0072
Echinococcus granulosus c src tyrosine kinase 0.0205 0.0241 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.0483 0.0961 0.0961
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0437 0.1333
Schistosoma mansoni serine/threonine-protein kinase 0.0357 0.0636 0.0636
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0346 0.0607 0.0607
Plasmodium falciparum thioredoxin reductase 0.3983 1 1
Echinococcus granulosus roundabout 2 0.0421 0.08 0.0792
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0246 0.0349 0.0349
Schistosoma mansoni roundabout 0.0401 0.0749 0.0749
Brugia malayi Protein kinase domain containing protein 0.0419 0.0796 0.0776
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Loa Loa (eye worm) programmed cell death 8 0.0366 0.0659 0.065
Brugia malayi protein-tyrosine kinase 0.0271 0.0413 0.0392
Loa Loa (eye worm) hypothetical protein 0.0182 0.0183 0.0174
Brugia malayi Protein kinase domain containing protein 0.0306 0.0503 0.0482
Echinococcus multilocularis c src tyrosine kinase 0.0205 0.0241 0.0233
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0246 0.0349 0.0341
Loa Loa (eye worm) LAD-2 short isoform 0.0219 0.0278 0.0269
Echinococcus multilocularis cyclin dependent kinase 19 0.1182 0.2767 0.2761
Brugia malayi hypothetical protein 0.0743 0.1632 0.1613
Schistosoma mansoni hypothetical protein 0.0402 0.0752 0.0752
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.022 0.0281 0.0281
Trichomonas vaginalis AGC family protein kinase 0.0635 0.1354 0.413
Brugia malayi GCC2 and GCC3 family protein 0.1146 0.2671 0.2655
Trichomonas vaginalis AGC family protein kinase 0.0373 0.0677 0.2064
Schistosoma mansoni protein kinase 0.0141 0.0076 0.0076
Echinococcus granulosus Vam6:Vps39 protein 0.0242 0.0339 0.033
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0533 0.1089 0.1082
Echinococcus granulosus protein jagged 2 0.0402 0.0752 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0115 0.001 0.003
Echinococcus multilocularis neurogenic locus protein delta 0.0402 0.0752 0.0744
Giardia lamblia Kinase, NEK 0.0297 0.0479 0.146
Loa Loa (eye worm) hypothetical protein 0.0242 0.0339 0.0329
Entamoeba histolytica protein kinase domain containing protein 0.028 0.0437 0.2174
Brugia malayi notch-like transmembrane receptor 0.0402 0.0752 0.0732
Echinococcus granulosus tyrosine kinase 0.0271 0.0413 0.0405
Onchocerca volvulus Netrin receptor homolog 0.0245 0.0345 0.1534
Brugia malayi cell division control protein 2 homolog 0.0259 0.0381 0.036
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.047 0.0926 0.0918
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0478 0.0947 0.0939
Onchocerca volvulus 0.0743 0.1632 0.7686
Brugia malayi MAP kinase sur-1 0.0183 0.0185 0.0163
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0366 0.0659 0.0659
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0366 0.0659 0.2004

Activities

Activity type Activity value Assay description Source Reference
Binding stoichiometry (binding) < 0.5 Binding stoichiometry to TTR in human blood plasma determined by antibody capture/HPLC method ChEMBL. 15743199
Formation (binding) = 9 % Percentage of WT-TTR (3.6 uM) amyloid fibril formation at pH 4.4 upon incubation with the compound (7.2 uM) ChEMBL. 15743199
Formation (binding) = 9 % Percentage of WT-TTR (3.6 uM) amyloid fibril formation at pH 4.4 upon incubation with the compound (7.2 uM) ChEMBL. 15743199

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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