Detailed information for compound 312774

Basic information

Technical information
  • TDR Targets ID: 312774
  • Name: 2-(furan-2-yl)-7-(3-piperazin-1-ylphenyl)-[1, 2,4]triazolo[5,1-f]pyrimidin-5-amine
  • MW: 361.4 | Formula: C19H19N7O
  • H donors: 2 H acceptors: 3 LogP: 1.64 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1nc(cc2n1nc(n2)c1ccco1)c1cccc(c1)N1CCNCC1
  • InChi: 1S/C19H19N7O/c20-19-22-15(12-17-23-18(24-26(17)19)16-5-2-10-27-16)13-3-1-4-14(11-13)25-8-6-21-7-9-25/h1-5,10-12,21H,6-9H2,(H2,20,22)
  • InChiKey: MQAJFAGHNPJXCS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-furyl)-7-(3-piperazin-1-ylphenyl)-[1,2,4]triazolo[5,1-f]pyrimidin-5-amine
  • 2-(2-furyl)-7-[3-(1-piperazinyl)phenyl]-[1,2,4]triazolo[5,1-f]pyrimidin-5-amine
  • [2-(2-furyl)-7-(3-piperazinophenyl)-[1,2,4]triazolo[5,1-f]pyrimidin-5-yl]amine
  • 2-furan-2-yl-7-(3-piperazin-1-ylphenyl)-[1,2,4]triazolo[5,1-f]pyrimidin-5-amine
  • [2-(2-furyl)-7-(3-piperazin-1-ylphenyl)-[1,2,4]triazolo[5,1-f]pyrimidin-5-yl]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni protein kinase 0.043 0.1875 0.1957
Schistosoma mansoni cell polarity protein 0.0179 0.0425 0.0444
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.011 0.0028 0.0018
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.0521 0.0533
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0195 0.0521 0.0533
Brugia malayi EGF-like domain containing protein 0.0179 0.0425 0.0425
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0304 0.1149 0.1086
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0184 0.0455 0.0475
Echinococcus multilocularis dual specificity testis specific protein kinase 0.043 0.1875 0.1948
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0159 0.0313 0.0316
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.021 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.011 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0127 0.0128 0.0439
Echinococcus multilocularis lachesin 0.0205 0.0579 0.0593
Brugia malayi Protein kinase domain containing protein 0.0157 0.0302 0.0302
Entamoeba histolytica protein kinase domain containing protein 0.027 0.095 0.3524
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0246 0.0814 0.0814
Echinococcus multilocularis roundabout 2 0.0602 0.2862 0.298
Plasmodium falciparum ferrodoxin reductase-like protein 0.0163 0.0333 0.0223
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0157 0.0302 0.0302
Schistosoma mansoni neuroglian 0.0223 0.0681 0.0711
Trypanosoma cruzi casein kinase, putative 0.021 0.0609 0.0635
Brugia malayi Temporarily assigned gene name protein 59 0.0219 0.0656 0.0656
Loa Loa (eye worm) TK/ROR protein kinase 0.0159 0.0313 0.0313
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0475 0.2131 0.2216
Onchocerca volvulus 0.0176 0.0408 0.1049
Entamoeba histolytica serine/threonine protein kinase, putative 0.0527 0.243 0.9072
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0219 0.0656 0.0684
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0163 0.0333 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Brugia malayi serine/threonine-protein kinase PAK 7 0.0452 0.2 0.2
Entamoeba histolytica protein kinase, putative 0.016 0.0321 0.1163
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0304 0.1149 0.119
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0163 0.0333 0.0348
Plasmodium falciparum serine/threonine protein kinase, putative 0.0228 0.071 0.0621
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0163 0.0333 0.0223
Echinococcus granulosus thioredoxin glutathione reductase 0.1768 0.9581 1
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Echinococcus granulosus dual specificity protein kinase clk2 0.0298 0.1116 0.1155
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0163 0.0334 0.0224
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0965 0.4956 0.5167
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0163 0.0333 0.0333
Trichomonas vaginalis CAMK family protein kinase 0.0527 0.243 0.8307
Echinococcus granulosus Immunoglobulin 0.0379 0.1577 0.1637
Schistosoma mansoni nephrin 0.0492 0.223 0.2328
Giardia lamblia Kinase, CMGC CK2 0.0194 0.0512 0.0772
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0298 0.1116 0.105
Loa Loa (eye worm) hypothetical protein 0.0219 0.0656 0.0656
Onchocerca volvulus 0.0572 0.2689 0.7011
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Toxoplasma gondii rhoptry neck protein RON9 0.033 0.1296 0.1241
Loa Loa (eye worm) hypothetical protein 0.0205 0.0579 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.1668 0.1741
Leishmania major hypothetical protein, conserved 0.0163 0.0333 0.0223
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0163 0.0333 0.1209
Echinococcus multilocularis peroxidasin 0.0206 0.0582 0.0597
Brugia malayi STE20-like kinase MST 0.05 0.2279 0.2279
Echinococcus multilocularis tyrosine protein kinase shark 0.0339 0.135 0.1399
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0157 0.0302 0.0305
Onchocerca volvulus 0.0163 0.0333 0.0851
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0182 0.0444 0.0453
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0163 0.0333 0.1209
Schistosoma mansoni titin 0.0205 0.0579 0.0604
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0293 0.1084 0.1084
Loa Loa (eye worm) hypothetical protein 0.011 0.0028 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.3053
Loa Loa (eye worm) TK protein kinase 0.0451 0.1994 0.1994
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.011 0.0028 0.0018
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0237 0.0762 0.0795
Loa Loa (eye worm) hypothetical protein 0.0236 0.0756 0.0756
Echinococcus granulosus pro neuregulin 2 membrane bound 0.011 0.0028 0.0018
Entamoeba histolytica cell division protein kinase 2, putative 0.023 0.0723 0.2671
Loa Loa (eye worm) AGC/PKN protein kinase 0.0566 0.266 0.266
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0396 0.0413
Loa Loa (eye worm) hypothetical protein 0.0113 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Echinococcus granulosus dual specificity testis-specific protein kinase 0.043 0.1875 0.1948
Loa Loa (eye worm) hypothetical protein 0.0353 0.1432 0.1432
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0355 0.1444 0.1498
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1768 0.9581 1
Entamoeba histolytica protein kinase, putative 0.0228 0.071 0.2622
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.2147 0.224
Brugia malayi cell division control protein 2 homolog 0.023 0.0723 0.0723
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0205 0.0579 0.0579
Echinococcus multilocularis growth factor receptor bound protein 2 0.012 0.0088 0.0081
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Plasmodium falciparum NIMA related kinase 1 0.0264 0.0918 0.0842
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0163 0.0333 0.0337
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0527 0.243 0.243
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0227 0.0704 0.0704
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Echinococcus multilocularis calcium activated potassium channel 0.0262 0.0904 0.0933
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0285 0.104 0.104
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0163 0.0333 0.0039
Plasmodium falciparum glycogen synthase kinase 3 0.025 0.0834 0.0753
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0354 0.0354
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0875 0.4439 0.4439
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0237 0.0762 0.0676
Schistosoma mansoni glutamate synthase 0.0163 0.0333 0.0348
Echinococcus granulosus neurogenic locus notch protein 0.0179 0.0425 0.0433
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0394 0.1668 0.1668
Trichomonas vaginalis CAMK family protein kinase 0.0527 0.243 0.8307
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0488 0.2209 0.2297
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.0681 0.2329
Echinococcus granulosus protein jagged 1 0.0179 0.0425 0.0433
Echinococcus multilocularis myosin iiia 0.0163 0.0338 0.0342
Brugia malayi Variant SH3 domain containing protein 0.0146 0.024 0.024
Plasmodium falciparum serine/threonine protein kinase 0.016 0.0321 0.021
Entamoeba histolytica protein kinase domain containing protein 0.0228 0.071 0.2622
Plasmodium falciparum thioredoxin reductase 0.0613 0.2925 0.2964
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0473 0.2122 0.2206
Echinococcus granulosus lachesin 0.0205 0.0579 0.0593
Onchocerca volvulus Neurogenic locus notch homolog 0.0179 0.0425 0.1093
Schistosoma mansoni protein kinase 0.0124 0.0109 0.0114
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0375 0.1557 0.1557
Brugia malayi Protein kinase domain containing protein 0.0128 0.0135 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0658 0.0687
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.021 0.0609 0.0609
Brugia malayi Protein kinase domain containing protein 0.0391 0.1647 0.1647
Loa Loa (eye worm) hypothetical protein 0.0508 0.2325 0.2325
Trypanosoma brucei NADH dehydrogenase 0.0163 0.0333 0.0223
Brugia malayi P38 map kinase family protein 2 0.0309 0.1177 0.1177
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0163 0.0333 0.0223
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Echinococcus multilocularis dual specificity protein kinase clk2 0.0298 0.1116 0.1155
Loa Loa (eye worm) hypothetical protein 0.0376 0.1563 0.1563
Schistosoma mansoni serine/threonine protein kinase 0.0527 0.243 0.2537
Loa Loa (eye worm) hypothetical protein 0.0221 0.067 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.0808 0.2764
Brugia malayi Protein kinase domain containing protein 0.0875 0.4439 0.4439
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0223 0.0681 0.0681
Brugia malayi Immunoglobulin domain containing protein 0.011 0.0028 0.0028
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0527 0.243 0.2528
Loa Loa (eye worm) hypothetical protein 0.0223 0.0681 0.0681
Schistosoma mansoni protein kinase 0.0166 0.0354 0.0369
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Echinococcus multilocularis expressed conserved protein 0.0163 0.0334 0.0338
Schistosoma mansoni tyrosine kinase 0.0339 0.135 0.1409
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.016 0.0321 0.021
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0605 0.2884 0.3003
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0613 0.2925 1
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0309 0.1177 0.1229
Echinococcus multilocularis serine:threonine protein kinase 3 0.05 0.2279 0.237
Entamoeba histolytica protein kinase domain containing protein 0.025 0.0834 0.3088
Echinococcus granulosus casein kinase I delta 0.021 0.0609 0.0625
Echinococcus granulosus cyclin dependent kinase 5 0.023 0.0723 0.0744
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0195 0.0521 0.0421
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0163 0.0333 0.0337
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0219 0.0656 0.0674
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.021 0.0609 0.0609
Schistosoma mansoni netrin receptor unc5 0.011 0.0028 0.0029
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0223 0.0681 0.0711
Loa Loa (eye worm) hypothetical protein 0.0151 0.0266 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0175 0.0402 0.0402
Brugia malayi Protein kinase domain containing protein 0.0128 0.0135 0.0135
Loa Loa (eye worm) thyroid receptor interactor 0.02 0.0549 0.0549
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0306 0.0319
Trichomonas vaginalis STE family protein kinase 0.0166 0.0354 0.1208
Plasmodium falciparum cGMP-dependent protein kinase 0.0163 0.0334 0.0224
Schistosoma mansoni notch 0.0179 0.0425 0.0444
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0028 0.0028
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0622 0.2982 0.2982
Brugia malayi EGF-like domain containing protein 0.0179 0.0425 0.0425
Brugia malayi Protein kinase domain containing protein 0.016 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Echinococcus granulosus hemicentin 1 0.0205 0.0579 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0391 0.1647 0.1719
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Echinococcus multilocularis CDC7 cell division cycle 7 0.0173 0.0396 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.2033 0.2122
Echinococcus multilocularis protein jagged 1 0.0179 0.0425 0.0433
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0299 0.1119 0.1158
Loa Loa (eye worm) hypothetical protein 0.0454 0.201 0.201
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.3053
Trypanosoma cruzi casein kinase, putative 0.021 0.0609 0.0635
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0165 0.0347 0.0347
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0379 0.1577 0.1646
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.2131 0.2224
Onchocerca volvulus 0.0179 0.0425 0.1093
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.2131 0.2224
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0266 0.0277
Echinococcus granulosus NCK adaptor protein 0.012 0.0088 0.0081
Echinococcus multilocularis Immunoglobulin 0.011 0.0028 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0723 0.2472
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0163 0.0333 0.0337
Loa Loa (eye worm) hypothetical protein 0.0205 0.0579 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0497 0.2258 0.2357
Schistosoma mansoni serine/threonine-protein kinase 0.0319 0.1235 0.1289
Echinococcus granulosus basement membrane specific heparan sulfate 0.011 0.0028 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.027 0.095 0.3249
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0769 0.3827 0.3827
Schistosoma mansoni serine/threonine protein kinase 0.059 0.2798 0.2921
Entamoeba histolytica serine/threonine protein kinase, putative 0.0151 0.0266 0.0956
Giardia lamblia Kinase, CDC7 0.0173 0.0396 0.0326
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0652 0.315 0.315
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0658 0.0687
Loa Loa (eye worm) hypothetical protein 0.0367 0.151 0.151
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0146 0.024 0.0239
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0328 0.1121
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Schistosoma mansoni peroxidasin 0.011 0.0031 0.0033
Entamoeba histolytica protein kinase, putative 0.0313 0.1199 0.4454
Echinococcus multilocularis c src tyrosine kinase 0.0184 0.0455 0.0464
Leishmania major hypothetical protein, conserved 0.0163 0.0333 0.0223
Entamoeba histolytica protein kinase, putative 0.0166 0.0354 0.1286
Trypanosoma brucei rac serine-threonine kinase, putative 0.057 0.2678 0.2702
Loa Loa (eye worm) variant SH3 domain-containing protein 0.012 0.0088 0.0088
Echinococcus granulosus dual specificity 0.027 0.095 0.0982
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0195 0.0521 0.0241
Brugia malayi SH2 domain containing protein 0.0428 0.1861 0.1861
Plasmodium vivax glutathione reductase, putative 0.1768 0.9581 1
Echinococcus multilocularis protein kinase c iota type 0.0557 0.2604 0.271
Brugia malayi Protein kinase domain containing protein 0.0313 0.1199 0.1199
Loa Loa (eye worm) hypothetical protein 0.0168 0.0364 0.0364
Brugia malayi Furin-like cysteine rich region family protein 0.0679 0.3306 0.3306
Leishmania major protein kinase A catalytic subunit isoform 2 0.0219 0.0658 0.0566
Loa Loa (eye worm) TK/INSR protein kinase 0.0588 0.2782 0.2782
Echinococcus multilocularis nervana 2 0.0242 0.079 0.0814
Trichomonas vaginalis glutathione reductase, putative 0.0613 0.2925 1
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0163 0.0333 0.0086
Echinococcus multilocularis raf serine:threonine protein kinase 0.0145 0.0234 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0534 0.2475 0.846
Toxoplasma gondii AGC kinase 0.0219 0.0658 0.0566
Loa Loa (eye worm) CDC7 protein kinase 0.0173 0.0396 0.0396
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Schistosoma mansoni disulfide oxidoreductase 0.0163 0.0333 0.0348
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0355 0.1444 0.1498
Echinococcus granulosus Glutaredoxin protein 5 0.0242 0.079 0.0814
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.2033 0.2122
Brugia malayi Protein kinase domain containing protein 0.0588 0.2782 0.2782
Echinococcus granulosus roundabout 2 0.0223 0.0681 0.0701
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0159 0.0313 0.0316
Echinococcus granulosus ephrin type A receptor 4 A 0.0189 0.0484 0.0495
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0555 0.2592 0.2592
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0613 0.2925 1
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Echinococcus multilocularis mitogen activated protein kinase 11 0.0309 0.1177 0.1219
Loa Loa (eye worm) hypothetical protein 0.0205 0.0579 0.0579
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0447 0.1973 0.205
Echinococcus multilocularis protein kinase shaggy 0.025 0.0834 0.0861
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.011 0.0028 0.0029
Giardia lamblia Kinase, AGC PKA 0.0304 0.1149 0.3208
Schistosoma mansoni growth factor receptor-bound protein 0.012 0.0088 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.071 0.0741
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0847 0.4274 0.4455
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0151 0.0266 0.0277
Schistosoma mansoni protein kinase 0.0375 0.1557 0.1625
Schistosoma mansoni serine/threonine protein kinase 0.0515 0.2362 0.2466
Loa Loa (eye worm) hypothetical protein 0.0396 0.168 0.168
Schistosoma mansoni serine/threonine protein kinase 0.0931 0.476 0.4968
Trichomonas vaginalis CMGC family protein kinase 0.025 0.0834 0.2852
Entamoeba histolytica PH domain containing protein kinase, putative 0.0234 0.0743 0.2747
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0281 0.1015 0.1049
Echinococcus granulosus tyrosine protein kinase otk 0.0205 0.0579 0.0593
Brugia malayi glutamate synthase 0.0163 0.0333 0.0333
Echinococcus multilocularis rho associated protein kinase 0.0634 0.3048 0.3174
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0163 0.0333 0.0223
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Brugia malayi Calcium binding EGF domain containing protein 0.0179 0.0425 0.0425
Schistosoma mansoni cell adhesion molecule 0.0113 0.0049 0.0051
Brugia malayi Heparan sulfate 0.011 0.0028 0.0028
Echinococcus granulosus protein jagged 2 0.0179 0.0425 0.0433
Trypanosoma cruzi cdc2-related kinase 3 0.023 0.0723 0.0755
Brugia malayi hypothetical protein 0.0219 0.0656 0.0656
Giardia lamblia High cysteine protein 0.0179 0.0425 0.0439
Giardia lamblia Kinase, NEK 0.0264 0.0918 0.2325
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0723 0.2472
Echinococcus granulosus roundabout 2 0.0602 0.2862 0.298
Echinococcus granulosus tyrosine protein kinase Src64B 0.0299 0.1119 0.1158
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0299 0.1119 0.1158
Toxoplasma gondii histone kinase SNF1, putative 0.0151 0.0266 0.0152
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0313 0.1199 0.1241
Leishmania major protein kinase, putative 0.0298 0.1116 0.105
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Echinococcus multilocularis protein kinase c epsilon type 0.0397 0.1684 0.1749
Onchocerca volvulus 0.0128 0.0135 0.0333
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0163 0.0333 0.1209
Brugia malayi Cadherin domain containing protein 0.0179 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0205 0.0579 0.0579
Schistosoma mansoni tyrosine kinase 0.0274 0.0978 0.1021
Plasmodium vivax ferrodoxin reductase, putative 0.0163 0.0333 0.0039
Brugia malayi EGF-like domain containing protein 0.0179 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0205 0.0579 0.0579
Trypanosoma cruzi casein kinase, putative 0.021 0.0609 0.0635
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0266 0.0277
Loa Loa (eye worm) projectin 0.0113 0.0049 0.0049
Schistosoma mansoni serine/threonine kinase 0.043 0.1874 0.1956
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Trypanosoma cruzi trypanothione reductase, putative 0.1768 0.9581 1
Schistosoma mansoni hypothetical protein 0.0113 0.0049 0.0051
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0309 0.1177 0.1116
Leishmania major protein kinase, putative 0.0298 0.1116 0.105
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0242 0.079 0.0814
Loa Loa (eye worm) hypothetical protein 0.0379 0.1577 0.1577
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0342 0.1365 0.1365
Loa Loa (eye worm) TK protein kinase 0.03 0.1127 0.1127
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0613 0.2925 0.2964
Loa Loa (eye worm) gastrulation defective protein 1 0.0528 0.2439 0.2439
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0613 0.2925 0.2964
Entamoeba histolytica casein kinase 1, putative 0.021 0.0609 0.2243
Echinococcus granulosus roundabout 2 0.0223 0.0681 0.0701
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0163 0.0333 0.0333
Giardia lamblia Aurora kinase 0.0228 0.071 0.1527
Toxoplasma gondii AGC kinase 0.0219 0.0658 0.0566
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Echinococcus granulosus tyrosine protein kinase Src42A 0.0182 0.0444 0.0453
Echinococcus multilocularis tyrosine protein kinase HCK 0.0179 0.0427 0.0435
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.027 0.095 0.095
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0163 0.0333 0.0337
Loa Loa (eye worm) hypothetical protein 0.0396 0.168 0.168
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0424 0.1837 0.1837
Schistosoma mansoni protein kinase 0.0847 0.4274 0.4462
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.016 0.0321 0.0321
Brugia malayi MAP kinase sur-1 0.0162 0.0328 0.0328
Brugia malayi Protein kinase domain containing protein 0.0297 0.1109 0.1109
Trichomonas vaginalis CMGC family protein kinase 0.027 0.095 0.3249
Giardia lamblia Thioredoxin reductase 0.0163 0.0333 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1233 0.1287
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0205 0.0579 0.0579
Schistosoma mansoni protein kinase 0.021 0.0609 0.0635
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0179 0.0425 0.1093
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Echinococcus granulosus nephrin 0.0113 0.0049 0.004
Schistosoma mansoni vav2 0.0161 0.0325 0.0339
Echinococcus multilocularis slit 2 protein 0.0222 0.0676 0.0695
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0163 0.0334 0.0338
Schistosoma mansoni protein kinase 0.0166 0.0354 0.0369
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0298 0.1116 0.1165
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Trypanosoma brucei Casein kinase II 0.0194 0.0512 0.0413
Schistosoma mansoni atypical protein kinase C 0.0569 0.2673 0.279
Plasmodium falciparum serine/threonine protein kinase KIN 0.0151 0.0266 0.0152
Echinococcus multilocularis activin receptor type 0.0126 0.0122 0.0117
Trypanosoma cruzi polo-like protein kinase, putative 0.0527 0.243 0.2537
Echinococcus granulosus serine threonine protein kinase nrc 0.0304 0.1149 0.119
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0126 0.0122 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0769 0.3827 0.3994
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0309 0.1177 0.1177
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0179 0.0425 0.0444
Giardia lamblia Kinase, CMGC CDK 0.023 0.0723 0.1578
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0194 0.0512 0.0512
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0242 0.079 0.0814
Entamoeba histolytica protein kinase, putative 0.0555 0.2592 0.968
Schistosoma mansoni protein kinase C mu 0.0424 0.1837 0.1917
Loa Loa (eye worm) CAMK protein kinase 0.0176 0.0408 0.0408
Brugia malayi Protein kinase domain containing protein 0.059 0.2798 0.2798
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Onchocerca volvulus 0.0611 0.2915 0.7603
Echinococcus granulosus cyclin dependent kinase 0.023 0.0723 0.0744
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0477 0.2147 0.2232
Echinococcus granulosus delta-like protein 1 0.0179 0.0425 0.0433
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0847 0.4274 0.4455
Onchocerca volvulus 0.0279 0.1006 0.2611
Schistosoma mansoni serine/threonine protein kinase 0.0433 0.1888 0.1971
Loa Loa (eye worm) hypothetical protein 0.0271 0.096 0.096
Echinococcus granulosus mitogen activated protein kinase 3 0.0162 0.0328 0.0331
Echinococcus granulosus protein kinase c epsilon type 0.0397 0.1684 0.1749
Brugia malayi Protein kinase domain containing protein 0.0298 0.1116 0.1116
Plasmodium falciparum calcium-dependent protein kinase 3 0.0195 0.0521 0.0421
Loa Loa (eye worm) TK/FER protein kinase 0.0428 0.1861 0.1861
Echinococcus granulosus cyclin 0.0417 0.18 0.187
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0162 0.0328 0.0342
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0515 0.2362 0.2362
Echinococcus granulosus twitchin 0.0536 0.2487 0.2587
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0688 0.3358 0.3358
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0688 0.3358 0.3497
Onchocerca volvulus 0.0148 0.0249 0.0633
Onchocerca volvulus 0.0173 0.0396 0.1016
Echinococcus multilocularis cyclin dependent kinase 1 0.023 0.0723 0.0744
Loa Loa (eye worm) protein kinase domain-containing protein 0.0415 0.1787 0.1787
Loa Loa (eye worm) TK protein kinase 0.0179 0.0427 0.0427
Echinococcus granulosus glutamate synthase 0.0163 0.0333 0.0337
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0319 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0219 0.0656 0.0656
Toxoplasma gondii AGC kinase 0.0555 0.2592 0.2612
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.05 0.2279 0.2279
Loa Loa (eye worm) hypothetical protein 0.011 0.0028 0.0028
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.016 0.0321 0.021
Schistosoma mansoni serine/threonine protein kinase 0.0634 0.3048 0.3182
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0163 0.0333 0.1138
Brugia malayi serine/threonine-protein kinase plk-2 0.0527 0.243 0.243
Onchocerca volvulus Tyrosine kinase homolog 0.077 0.3832 1
Onchocerca volvulus 0.021 0.0609 0.1572
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0049 0.0049
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0146 0.024 0.024
Echinococcus granulosus tyrosine protein kinase Blk 0.0243 0.0799 0.0824
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0049 0.0049
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.0521 0.0533
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0163 0.0333 0.0223
Schistosoma mansoni basigin related 0.011 0.0028 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.1116 0.3814
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0613 0.2925 1
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0163 0.0333 0.0337
Schistosoma mansoni cell adhesion molecule 0.0205 0.0579 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0302 0.0316
Onchocerca volvulus 0.0128 0.0135 0.0333
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0219 0.0658 0.0566
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0613 0.2925 0.3053
Schistosoma mansoni netrin receptor unc5 0.0166 0.0354 0.037
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0334 0.0349
Echinococcus multilocularis epidermal growth factor receptor 0.0473 0.2122 0.2206
Echinococcus multilocularis aurora kinase A 0.0228 0.071 0.0731
Schistosoma mansoni laminin gamma-3 chain 0.0179 0.0425 0.0444
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0613 0.2925 1
Giardia lamblia Kinase, CMGC DYRK 0.027 0.095 0.2447
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0613 0.2925 0.3046
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0613 0.2925 0.2964
Toxoplasma gondii rhoptry neck protein RON1 0.033 0.1296 0.1241
Loa Loa (eye worm) hypothetical protein 0.0364 0.1495 0.1495
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0163 0.0333 0.0223
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0242 0.0789 0.0705
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0814 0.085
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0157 0.0302 0.0305
Leishmania major protein kinase A catalytic subunit isoform 1 0.0219 0.0658 0.0566
Loa Loa (eye worm) hypothetical protein 0.0364 0.1495 0.1495
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0458 0.2033 0.2113
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0163 0.0333 0.0348
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0424 0.1837 0.1837
Plasmodium falciparum protein kinase 5 0.023 0.0723 0.0635
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0228 0.071 0.2622
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0579 0.0579
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0298 0.1116 0.1165
Giardia lamblia Kinase, STE STE20 0.0166 0.0354 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Echinococcus granulosus protein tyrosine kinase 0.0563 0.2643 0.275
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0609 0.2081
Plasmodium vivax serine/threonine kinase-1, putative 0.0298 0.1116 0.0882
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0131 0.0131
Echinococcus granulosus tyrosine protein kinase Srms 0.0531 0.2455 0.2554
Plasmodium vivax protein kinase Crk2 0.023 0.0723 0.0459
Brugia malayi protein-tyrosine kinase 0.0243 0.0799 0.0799
Brugia malayi Protein kinase domain containing protein 0.0128 0.0135 0.0135
Onchocerca volvulus 0.0361 0.1477 0.3843
Entamoeba histolytica casein kinase, putative 0.0194 0.0512 0.1881
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0379 0.1577 0.1637
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0313 0.1199 0.1241
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0579 0.0579
Echinococcus multilocularis fat cadherin tumor suppressor 0.0179 0.0425 0.0433
Schistosoma mansoni hypothetical protein 0.0199 0.0545 0.0568
Onchocerca volvulus 0.0179 0.0425 0.1093
Schistosoma mansoni tyrosine kinase 0.0409 0.1755 0.1832
Echinococcus multilocularis serine:threonine protein kinase N2 0.0254 0.0858 0.0885
Echinococcus granulosus epidermal growth factor receptor 0.0473 0.2122 0.2206
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0613 0.2925 0.2964
Echinococcus granulosus casein kinase i 0.021 0.0609 0.0625
Onchocerca volvulus Putative cubilin 0.0179 0.0425 0.1093
Echinococcus granulosus protein kinase 0.0297 0.111 0.1149
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0299 0.1119 0.1158
Trichomonas vaginalis glutamate synthase, putative 0.0163 0.0333 0.1138
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Leishmania major protein kinase, putative 0.0163 0.0338 0.0228
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0304 0.1149 0.12
Brugia malayi Protein kinase domain containing protein 0.057 0.2678 0.2678
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0613 0.2925 0.2964
Schistosoma mansoni myosin-binding protein-related 0.0113 0.0049 0.0051
Trypanosoma cruzi cdc2-related kinase 1 0.023 0.0723 0.0755
Brugia malayi Kinase associated domain 1 family protein 0.0199 0.0545 0.0545
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0162 0.0328 0.0328
Giardia lamblia Kinase, AGC PKA 0.0219 0.0658 0.1329
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.027 0.095 0.0876
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Onchocerca volvulus 0.033 0.1296 0.337
Plasmodium falciparum glutathione reductase 0.1768 0.9581 1
Onchocerca volvulus 0.0113 0.0049 0.0109
Schistosoma mansoni serine/threonine-protein kinase 0.0319 0.1235 0.1289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0579 0.0579
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0391 0.1646 0.1709
Brugia malayi serine/threonine kinase 12 0.0228 0.071 0.071
Loa Loa (eye worm) AUR protein kinase 0.0228 0.071 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.1116 0.1165
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0195 0.0521 0.0241
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0328 0.1121
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0299 0.1119 0.1158
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0163 0.0333 0.0337
Loa Loa (eye worm) AGC/PKG protein kinase 0.0163 0.0334 0.0334
Schistosoma mansoni tyrosine kinase 0.0473 0.2122 0.2215
Entamoeba histolytica protein kinase domain containing protein 0.0237 0.0762 0.2816
Echinococcus multilocularis casein kinase I alpha 0.021 0.0609 0.0625
Brugia malayi Immunoglobulin I-set domain containing protein 0.0176 0.0408 0.0408
Onchocerca volvulus 0.0128 0.0135 0.0333
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0195 0.0521 0.0521
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0609 0.2081
Toxoplasma gondii EGF family domain-containing protein 0.0179 0.0425 0.032
Echinococcus granulosus insulin receptor 0.0588 0.2782 0.2896
Trypanosoma brucei protein kinase, putative 0.0169 0.0373 0.0265
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0321 0.0335
Schistosoma mansoni cell adhesion molecule 0.0223 0.0681 0.0711
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Schistosoma mansoni glutamate synthase 0.0163 0.0333 0.0348
Brugia malayi SH2 domain containing protein 0.0128 0.0135 0.0135
Onchocerca volvulus Netrin receptor homolog 0.0152 0.0272 0.0693
Trichomonas vaginalis glutamate synthase, putative 0.0163 0.0333 0.1138
Echinococcus granulosus protein jagged 2 0.0179 0.0425 0.0433
Trichomonas vaginalis CAMK family protein kinase 0.0422 0.1829 0.6254
Echinococcus granulosus dual specificity 0.027 0.095 0.0982
Entamoeba histolytica protein kinase , putative 0.0228 0.071 0.2622
Brugia malayi Egg laying defective protein 4 0.0163 0.0334 0.0334
Entamoeba histolytica protein kinase domain containing protein 0.0394 0.1668 0.6213
Echinococcus multilocularis casein kinase I gamma 0.0415 0.1787 0.1857
Schistosoma mansoni notch 0.0179 0.0425 0.0444
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Trichomonas vaginalis AGC family protein kinase 0.0228 0.071 0.2426
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0515 0.2362 0.2457
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0049 0.0049
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0163 0.0333 0.1138
Echinococcus multilocularis tyrosine kinase 0.0128 0.0135 0.013
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Brugia malayi Immunoglobulin I-set domain containing protein 0.0396 0.168 0.168
Brugia malayi basement membrane proteoglycan 0.011 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0163 0.0333 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0521 0.0543
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0512 0.1881
Schistosoma mansoni sulfide quinone reductase 0.0163 0.0333 0.0348
Echinococcus multilocularis tyrosine protein kinase Abl 0.0184 0.0455 0.0464
Echinococcus granulosus cyclin dependent kinase 19 0.059 0.2798 0.2913
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0723 0.0755
Brugia malayi protein kinase C II. 0.0397 0.1684 0.1684
Onchocerca volvulus 0.033 0.1296 0.337
Echinococcus granulosus serine:threonine protein kinase N2 0.0254 0.0858 0.0885
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0246 0.0814 0.084
Schistosoma mansoni sulfide quinone reductase 0.0163 0.0333 0.0348
Loa Loa (eye worm) AGC/PKA protein kinase 0.0219 0.0658 0.0658
Echinococcus granulosus glycogen synthase kinase 3 beta 0.025 0.0834 0.0861
Trypanosoma cruzi hypothetical protein, conserved 0.0163 0.0333 0.0348
Schistosoma mansoni nck2/grb4 0.012 0.0088 0.0092
Loa Loa (eye worm) casein kinase 0.0353 0.1428 0.1428
Brugia malayi Delta serrate ligand family protein 0.0179 0.0425 0.0425
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0299 0.1119 0.1158
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.0808 0.2764
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0151 0.0266 0.0266
Echinococcus granulosus calcium activated potassium channel 0.0262 0.0904 0.0933
Schistosoma mansoni tyrosine kinase 0.0299 0.1119 0.1168
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Schistosoma mansoni vesicular amine transporter 0.0379 0.1577 0.1646
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Echinococcus granulosus serine/threonine protein kinase 0.0319 0.1235 0.1279
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0613 0.2925 0.2964
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0156 0.0297 0.0185
Echinococcus multilocularis tyrosine protein kinase Srms 0.0243 0.0799 0.0824
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0163 0.0333 0.0223
Loa Loa (eye worm) hypothetical protein 0.0206 0.0581 0.0581
Giardia lamblia Kinase, CMGC CDK 0.023 0.0723 0.1578
Echinococcus granulosus rho-associated protein kinase 1 0.0634 0.3048 0.3174
Brugia malayi Protein kinase domain containing protein 0.0221 0.067 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Loa Loa (eye worm) AGC/AKT protein kinase 0.057 0.2678 0.2678
Loa Loa (eye worm) LAD-2 short isoform 0.011 0.0028 0.0028
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0652 0.315 0.315
Brugia malayi Peroxidasin 0.0206 0.0582 0.0582
Loa Loa (eye worm) hypothetical protein 0.0163 0.0333 0.0333
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0299 0.1119 0.1158
Trichomonas vaginalis CMGC family protein kinase 0.027 0.095 0.3249
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0458 0.2033 0.2113
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0309 0.1177 0.1116
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0904 0.0943
Brugia malayi EGF-like domain containing protein 0.0179 0.0425 0.0425
Echinococcus multilocularis rac serine:threonine kinase 0.0319 0.1235 0.1279
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0271 0.0956 0.3267
Brugia malayi hypothetical protein 0.0396 0.168 0.168
Schistosoma mansoni hypothetical protein 0.011 0.0028 0.0029
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0219 0.0656 0.0684
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.067 0.0689
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0723 0.0755
Echinococcus multilocularis serine:threonine protein kinase N2 0.0313 0.1199 0.1241
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0681 0.0681
Entamoeba histolytica protein kinase, putative 0.0228 0.071 0.2622
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0609 0.0635
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0298 0.1116 0.1165
Schistosoma mansoni protein kinase 0.0194 0.0512 0.0535
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0146 0.024 0.025
Echinococcus multilocularis cyclin dependent kinase 9 0.0114 0.0055 0.0047
Echinococcus granulosus C type lectin domian containing protein 0.033 0.1296 0.1344
Entamoeba histolytica protein kinase domain containing protein 0.025 0.0834 0.3088
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0347 0.1186
Echinococcus granulosus neurogenic locus notch protein 4 0.0179 0.0425 0.0433
Echinococcus granulosus peroxidasin 0.0206 0.0582 0.0597
Brugia malayi Protein kinase domain containing protein 0.0319 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0199 0.0545 0.0545
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0223 0.0681 0.0701
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.2964
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.3053
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0228 0.071 0.2622
Toxoplasma gondii thioredoxin reductase 0.1768 0.9581 1
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.025 0.0834 0.0753
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0228 0.071 0.0731
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.025 0.0834 0.0871
Brugia malayi Protein kinase domain 0.0166 0.0354 0.0354
Schistosoma mansoni titin 0.0176 0.0408 0.0426
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0355 0.1444 0.1498
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0163 0.0333 0.1138
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0613 0.2925 1
Leishmania major protein kinase, putative 0.0195 0.0521 0.0421
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0223 0.0681 0.0701
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0142 0.0217 0.0217
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0151 0.0266 0.0152
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0163 0.0333 0.0333
Echinococcus granulosus calcium dependent protein kinase 0.0133 0.0161 0.0157
Echinococcus multilocularis casein kinase I alpha 0.021 0.0609 0.0625
Toxoplasma gondii aurora kinase 0.0228 0.071 0.0621
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0319 0.1235 0.1289
Echinococcus multilocularis Immunoglobulin 0.0379 0.1577 0.1637
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Schistosoma mansoni protein kinase 0.0847 0.4274 0.4462
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Brugia malayi Protein kinase domain containing protein 0.0333 0.1315 0.1315
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0688 0.3358 0.3358
Brugia malayi p70 ribosomal S6 kinase beta 0.0555 0.2592 0.2592
Echinococcus multilocularis leucine rich repeat containing protein 4 0.011 0.0028 0.0018
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.023 0.0723 0.0635
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0397 0.1684 0.1684
Trichomonas vaginalis CAMK family protein kinase 0.0527 0.243 0.8307
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0299 0.1119 0.1158
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Echinococcus multilocularis tyrosine protein kinase otk 0.0205 0.0579 0.0593
Leishmania major protein kinase, putative 0.0228 0.071 0.0621
Echinococcus granulosus tyrosine protein kinase HCK 0.0179 0.0427 0.0435
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0166 0.0354 0.0358
Echinococcus granulosus epidermal growth factor receptor 0.0679 0.3306 0.3444
Brugia malayi Sushi domain 0.033 0.1296 0.1296
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Brugia malayi SRC-1 0.0299 0.1119 0.1119
Schistosoma mansoni tyrosine kinase 0.0409 0.1755 0.1832
Trypanosoma cruzi trypanothione reductase, putative 0.0613 0.2925 0.3053
Echinococcus granulosus casein kinase I alpha 0.021 0.0609 0.0625
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0762 0.0795
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0447 0.1973 0.205
Loa Loa (eye worm) hypothetical protein 0.0488 0.2209 0.2209
Plasmodium falciparum calcium-dependent protein kinase 5 0.0195 0.0521 0.0421
Echinococcus multilocularis mitogen activated protein kinase 14 0.0309 0.1177 0.1219
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0128 0.0135 0.013
Echinococcus granulosus mitogen activated protein kinase 14 0.0309 0.1177 0.1219
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0127 0.0131 0.0126
Schistosoma mansoni hypothetical protein 0.0219 0.0656 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0334 0.0349
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.1199 0.1251
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Schistosoma mansoni cell adhesion molecule 0.011 0.0028 0.0029
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0163 0.0333 0.0348
Leishmania major protein kinase A catalytic subunit 0.0219 0.0658 0.0566
Echinococcus granulosus cyclin dependent kinase 9 0.0114 0.0055 0.0047
Brugia malayi hypothetical protein 0.0433 0.1888 0.1888
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0433 0.1888 0.1962
Loa Loa (eye worm) hypothetical protein 0.0205 0.0579 0.0579
Echinococcus granulosus protein kinase shaggy 0.025 0.0834 0.0861
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0146 0.024 0.025
Echinococcus granulosus serine:threonine protein kinase MARK2 0.042 0.1819 0.1889
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.3053
Schistosoma mansoni hemicentin 0.0113 0.0049 0.0051
Echinococcus multilocularis dual specificity 0.0237 0.0762 0.0785
Schistosoma mansoni cell adhesion molecule 0.0113 0.0049 0.0051
Loa Loa (eye worm) TK/EGFR protein kinase 0.0679 0.3306 0.3306
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.3053
Schistosoma mansoni protein kinase 0.0516 0.2369 0.2473
Loa Loa (eye worm) hypothetical protein 0.0175 0.0402 0.0402
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0319 0.1233 0.1278
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.023 0.0723 0.0635
Onchocerca volvulus 0.033 0.1296 0.337
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0163 0.0333 0.0039
Mycobacterium tuberculosis Probable oxidoreductase 0.0613 0.2925 0.2803
Schistosoma mansoni ephrin receptor 0.0189 0.0484 0.0506
Schistosoma mansoni hypothetical protein 0.011 0.0028 0.0029
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0163 0.0333 0.0348
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.045 0.1989 0.1989
Echinococcus granulosus Immunoglobulin 0.011 0.0028 0.0018
Brugia malayi probable protein kinase 0.0516 0.2369 0.2369
Brugia malayi Protein kinase domain containing protein 0.0119 0.0081 0.0081
Echinococcus multilocularis dual specificity 0.027 0.095 0.0982
Trypanosoma cruzi cdc2-related kinase 1 0.023 0.0723 0.0755
Entamoeba histolytica protein kinase, putative 0.057 0.2678 1
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0246 0.0814 0.0814
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0219 0.0658 0.0566
Echinococcus multilocularis c4b binding protein beta chain 0.033 0.1296 0.1344
Entamoeba histolytica protein kinase, putative 0.057 0.2678 1
Echinococcus multilocularis C type lectin domian containing protein 0.033 0.1296 0.1344
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0126 0.0122 0.0128
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.011 0.0028 0.0018
Loa Loa (eye worm) AUR protein kinase 0.0228 0.071 0.071
Brugia malayi Cam kinase protein 1 0.0195 0.0521 0.0521
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0613 0.2925 0.2831
Plasmodium falciparum calcium-dependent protein kinase 4 0.0195 0.0521 0.0421
Entamoeba histolytica protein kinase, putative 0.0237 0.0762 0.2816
Echinococcus granulosus protein jagged 1 0.0179 0.0425 0.0433
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0163 0.0334 0.0338
Echinococcus multilocularis casein kinase ii subunit alpha 0.0194 0.0512 0.0524
Loa Loa (eye worm) hypothetical protein 0.0622 0.2982 0.2982
Echinococcus granulosus tyrosine protein kinase Fyn 0.0299 0.1119 0.1158
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0219 0.0658 0.0566
Echinococcus multilocularis tyrosine protein kinase Blk 0.0243 0.0799 0.0824
Onchocerca volvulus 0.0122 0.0098 0.0238
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0127 0.0131 0.0126
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Onchocerca volvulus 0.0634 0.3048 0.795
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.042 0.1819 0.1889
Echinococcus granulosus casein kinase I delta 0.021 0.0609 0.0625
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0028 0.0028
Echinococcus multilocularis 0.0297 0.111 0.1149
Brugia malayi Serine/threonine-protein kinase SULU 0.0433 0.1888 0.1888
Echinococcus multilocularis dual specificity 0.027 0.095 0.0982
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.023 0.0723 0.0723
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0715 0.3518 0.3665
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1426 0.7614 0.7945
Schistosoma mansoni tyrosine kinase 0.0679 0.3306 0.3451
Trichomonas vaginalis CAMK family protein kinase 0.0527 0.243 0.8307
Echinococcus multilocularis mitogen activated protein kinase 3 0.0162 0.0328 0.0331
Entamoeba histolytica protein kinase, putative 0.0124 0.0109 0.0369
Schistosoma mansoni tyrosine kinase 0.0299 0.1119 0.1168
Brugia malayi phosphoinositide-dependent protein kinase I 0.0157 0.0302 0.0302
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0319 0.1233 0.1278
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0166 0.0354 0.0358
Brugia malayi Fes/CIP4 homology domain containing protein 0.02 0.0549 0.0549
Onchocerca volvulus 0.0128 0.0135 0.0333
Loa Loa (eye worm) CMGC/GSK protein kinase 0.025 0.0834 0.0834
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0394 0.1668 0.1668
Trichomonas vaginalis AGC family protein kinase 0.0228 0.071 0.2426
Echinococcus granulosus contactin 0.0223 0.0681 0.0701
Loa Loa (eye worm) hypothetical protein 0.0379 0.1577 0.1577
Trypanosoma cruzi polo-like protein kinase, putative 0.0527 0.243 0.2537
Onchocerca volvulus 0.0179 0.0425 0.1093
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.016 0.0321 0.0335
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0221 0.067 0.067
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0613 0.2925 0.3053
Entamoeba histolytica protein kinase, putative 0.0139 0.0195 0.0689
Brugia malayi Protein kinase domain containing protein 0.023 0.0723 0.0723
Schistosoma mansoni septate junction protein 0.0179 0.0425 0.0444
Schistosoma mansoni serine/threonine protein kinase 0.0397 0.1684 0.1758
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.023 0.0723 0.0635
Schistosoma mansoni kinase 0.0563 0.2638 0.2754
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0298 0.1116 0.1165
Trichomonas vaginalis AGC family protein kinase 0.0264 0.0918 0.314
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0297 0.111 0.111
Trypanosoma cruzi NADH dehydrogenase, putative 0.0163 0.0333 0.0348
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0454 0.201 0.2089
Loa Loa (eye worm) notch protein 0.0179 0.0425 0.0425
Onchocerca volvulus Serine\/threonine kinase homolog 0.0527 0.243 0.6334
Onchocerca volvulus 0.033 0.1296 0.337
Echinococcus granulosus neuroglian 0.0474 0.2127 0.2212
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0613 0.2925 0.2964
Trichomonas vaginalis STE family protein kinase 0.0163 0.0338 0.1156
Echinococcus multilocularis nervana 2 0.0242 0.079 0.0814
Trypanosoma brucei trypanothione reductase 0.1768 0.9581 1
Loa Loa (eye worm) hypothetical protein 0.0271 0.096 0.096
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0195 0.0521 0.0421
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0163 0.0333 0.1138
Echinococcus granulosus notch 0.0179 0.0425 0.0433
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0237 0.0762 0.0762
Loa Loa (eye worm) hypothetical protein 0.0279 0.1006 0.1006
Plasmodium falciparum casein kinase 2, alpha subunit 0.0194 0.0512 0.0413
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0162 0.0328 0.0217
Loa Loa (eye worm) cyclin domain-containing protein 0.0417 0.18 0.18
Echinococcus multilocularis 0.0188 0.048 0.0491
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0163 0.0333 0.0337
Echinococcus multilocularis serine:threonine protein kinase 38 0.0313 0.1199 0.1241
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0163 0.0338 0.1228
Trichomonas vaginalis CAMK family protein kinase 0.0527 0.243 0.8307
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Onchocerca volvulus Serine\/threonine kinase homolog 0.0319 0.1233 0.3205
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Trichomonas vaginalis STE family protein kinase 0.0166 0.0354 0.1208
Plasmodium falciparum protein serine/threonine kinase-1 0.0298 0.1116 0.105
Trichomonas vaginalis CMGC family protein kinase 0.027 0.095 0.3249
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0195 0.0521 0.0521
Loa Loa (eye worm) hypothetical protein 0.0233 0.0737 0.0737
Echinococcus multilocularis neurogenic locus protein delta 0.0179 0.0425 0.0433
Giardia lamblia Kinase, PLK 0.0527 0.243 0.8106
Entamoeba histolytica p21-activated kinase 0.0181 0.0439 0.1606
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.067 0.0689
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0223 0.0681 0.0701
Trypanosoma cruzi casein kinase, putative 0.021 0.0609 0.0635
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0219 0.0658 0.0687
Echinococcus granulosus serine:threonine protein kinase MARK2 0.042 0.1819 0.1889
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.025 0.0834 0.0861
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0417 0.18 0.187
Trichomonas vaginalis STE family protein kinase 0.0166 0.0354 0.1208
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.023 0.0723 0.0723
Echinococcus multilocularis notch 0.0179 0.0425 0.0433
Plasmodium vivax thioredoxin reductase, putative 0.1768 0.9581 1
Brugia malayi Protein kinase domain containing protein 0.0415 0.1787 0.1787
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0163 0.0333 0.0337
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0613 0.2925 0.2831
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0146 0.024 0.0239
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0281 0.1015 0.1049
Trichomonas vaginalis AGC family protein kinase 0.0348 0.14 0.4787
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0391 0.1647 0.1647
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0304 0.1149 0.119
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0162 0.0328 0.0217
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0163 0.0333 0.0223
Echinococcus granulosus neural cadherin 0.0179 0.0425 0.0433
Onchocerca volvulus 0.0128 0.0135 0.0333
Echinococcus multilocularis twitchin 0.0158 0.0306 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.027 0.095 0.3249
Echinococcus multilocularis casein kinase I delta 0.021 0.0609 0.0625
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0302 0.1034
Echinococcus granulosus slit 2 protein 0.0222 0.0676 0.0695
Giardia lamblia NADH oxidase lateral transfer candidate 0.0613 0.2925 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0163 0.0334 0.0338
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0328 0.1121
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0477 0.2147 0.2232
Brugia malayi glutathione reductase 0.1768 0.9581 0.9581
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0163 0.0338 0.0353
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0205 0.0579 0.1493
Echinococcus granulosus tyrosine protein kinase ABL1 0.0128 0.0135 0.013
Schistosoma mansoni protein kinase 0.0126 0.0122 0.0128
Echinococcus granulosus titin 0.0176 0.0408 0.0416
Echinococcus multilocularis N chimaerin 0.0146 0.024 0.0239
Loa Loa (eye worm) hypothetical protein 0.0159 0.0314 0.0314
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0157 0.0299 0.0301
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0163 0.0338 0.0228
Schistosoma mansoni g1/s-specific cyclin C 0.0834 0.4202 0.4386
Echinococcus granulosus defective proboscis extension response 0.0379 0.1577 0.1637
Brugia malayi Calcium binding EGF domain containing protein 0.0179 0.0425 0.0425
Entamoeba histolytica PH domain containing protein kinase, putative 0.0234 0.0743 0.2747
Echinococcus multilocularis serine:threonine protein kinase N2 0.0566 0.266 0.2768
Brugia malayi Protein kinase domain containing protein 0.0275 0.098 0.098
Loa Loa (eye worm) glutathione reductase 0.1768 0.9581 0.9581
Schistosoma mansoni tyrosine kinase 0.0184 0.0455 0.0475
Plasmodium falciparum apical sushi protein 0.033 0.1296 0.1241
Trypanosoma brucei SNF1-related protein kinases, putative 0.0151 0.0266 0.0152
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Entamoeba histolytica PH domain containing protein kinase, putative 0.0319 0.1235 0.459
Loa Loa (eye worm) hypothetical protein 0.0279 0.1006 0.1006
Trypanosoma cruzi cdc2-related kinase 3 0.023 0.0723 0.0755
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.027 0.095 0.0992
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0011 0.0011
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0163 0.0333 0.0223
Loa Loa (eye worm) SRC-1 0.0299 0.1119 0.1119
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0281 0.1016 0.1051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0451 0.1994 0.1994
Schistosoma mansoni tyrosine kinase 0.0394 0.1664 0.1737
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0205 0.0579 0.0593
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0205 0.0579 0.0604
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.1787 0.1866
Trypanosoma brucei cdc2-related kinase 1 0.023 0.0723 0.0635
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0299 0.1119 0.1158
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Schistosoma mansoni notch 0.0179 0.0425 0.0444
Onchocerca volvulus 0.033 0.1296 0.337
Echinococcus granulosus dual specificity 0.027 0.095 0.0982
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0163 0.0338 0.1228
Echinococcus granulosus nervana 2 0.0242 0.079 0.0814
Brugia malayi Protein kinase c protein 2 0.0224 0.0688 0.0688
Schistosoma mansoni adapter molecule crk 0.012 0.0088 0.0092
Echinococcus granulosus low density lipoprotein receptor ldl 0.011 0.0028 0.0018
Echinococcus multilocularis ephrin type A receptor 4 A 0.0189 0.0484 0.0495
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0163 0.0333 0.1138
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0148 0.0249 0.026
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0166 0.0354 0.0358
Echinococcus multilocularis glutamate synthase 0.0163 0.0333 0.0337
Echinococcus granulosus NDR protein kinase 0.0313 0.1199 0.1241
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Echinococcus multilocularis Immunoglobulin subtype 0.011 0.0028 0.0018
Leishmania major trypanothione reductase 0.1768 0.9581 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.0195 0.0521 0.0421
Loa Loa (eye worm) hypothetical protein 0.0396 0.168 0.168
Echinococcus granulosus growth factor receptor bound protein 2 0.0122 0.01 0.0093
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0527 0.243 0.244
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0163 0.0333 0.1138
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.067 0.2291
Echinococcus multilocularis casein kinase I alpha 0.021 0.0609 0.0625
Schistosoma mansoni notch 0.0179 0.0425 0.0444
Plasmodium vivax casein kinase 1, putative 0.021 0.0609 0.0336
Entamoeba histolytica protein kinase, putative 0.0179 0.0427 0.1561
Giardia lamblia Kinase, CMGC GSK 0.025 0.0834 0.2003
Schistosoma mansoni nephrin related 0.011 0.0028 0.0029
Loa Loa (eye worm) hypothetical protein 0.0195 0.0521 0.0521
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0219 0.0656 0.0684
Brugia malayi pregnancy-associated plasma protein-A 0.033 0.1296 0.1296
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.0521 0.0533
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.067 0.0689
Echinococcus granulosus cGMP dependent protein kinase 1 0.0163 0.0334 0.0338
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0394 0.1668 0.1732
Loa Loa (eye worm) TK protein kinase 0.0243 0.0799 0.0799
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0223 0.0681 0.0701
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0163 0.0333 0.1138
Brugia malayi protein kinase C3,putative 0.0306 0.1161 0.1161
Brugia malayi casein kinase 1, delta 0.021 0.0609 0.0609
Loa Loa (eye worm) hypothetical protein 0.0903 0.4596 0.4596
Schistosoma mansoni hypothetical protein 0.011 0.0028 0.0029
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.059 0.2798 0.2798
Echinococcus granulosus aurora kinase A 0.0228 0.071 0.0731
Echinococcus granulosus c-Jun N-terminal kinases 0.0515 0.2362 0.2457
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0049 0.0049
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0219 0.0658 0.0566
Trypanosoma cruzi aurora B kinase, putative 0.0228 0.071 0.0741
Echinococcus multilocularis insulin receptor 0.0588 0.2782 0.2896
Trichomonas vaginalis STE family protein kinase 0.0124 0.0109 0.0373
Entamoeba histolytica protein kinase domain containing protein 0.0126 0.0122 0.0418
Trypanosoma cruzi Protein kinase B 0.0319 0.1235 0.1289
Brugia malayi Calcium binding EGF domain containing protein 0.0179 0.0425 0.0425
Trichomonas vaginalis CMGC family protein kinase 0.025 0.0834 0.2852
Echinococcus granulosus nervana 2 0.0242 0.079 0.0814
Schistosoma mansoni kinase 0.0107 0.0011 0.0011
Echinococcus granulosus protein kinase c iota type 0.0557 0.2604 0.271
Echinococcus granulosus mitogen activated protein kinase 0.0162 0.0328 0.0331
Brugia malayi Immunoglobulin I-set domain containing protein 0.0139 0.0197 0.0197
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0223 0.0681 0.0701
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0313 0.1199 0.1241
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0234 0.0244
Schistosoma mansoni rap gtpase-activating protein 0.0219 0.0656 0.0684
Brugia malayi Protein kinase domain containing protein 0.0377 0.1568 0.1568
Brugia malayi casein kinase I 0.021 0.0609 0.0609
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0195 0.0521 0.0421
Schistosoma mansoni c4b-binding protein beta chain 0.033 0.1296 0.1353
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0299 0.1119 0.1158
Schistosoma mansoni notch 0.0179 0.0425 0.0444
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0422 0.1829 0.1829
Onchocerca volvulus 0.0179 0.0425 0.1093
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0163 0.0333 0.1209
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Schistosoma mansoni slit 0.0179 0.0428 0.0447
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.045 0.1989 0.1989
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.016 0.0321 0.021
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0223 0.0681 0.0701
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0128 0.0135 0.0466
Brugia malayi Cadherin domain containing protein 0.0179 0.0425 0.0425
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.023 0.0723 0.0744
Echinococcus granulosus tyrosine kinase 0.0128 0.0135 0.013
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0264 0.0918 0.0842
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0176 0.0408 0.0408
Echinococcus multilocularis hemicentin 1 0.0205 0.0579 0.0593
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0246 0.0814 0.084
Echinococcus granulosus Vam6:Vps39 protein 0.0219 0.0656 0.0674
Brugia malayi Protein kinase domain containing protein 0.0375 0.1557 0.1557
Brugia malayi basement membrane proteoglycan precursor 0.011 0.0028 0.0028
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0151 0.0266 0.0152
Entamoeba histolytica protein kinase, putative 0.0237 0.0762 0.2816
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0428 0.1861 0.1934
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0237 0.0762 0.0676
Loa Loa (eye worm) hypothetical protein 0.0211 0.0614 0.0614
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0151 0.0266 0.0267
Echinococcus multilocularis neural cadherin 0.0179 0.0425 0.0433
Plasmodium falciparum calcium-dependent protein kinase 2 0.0195 0.0521 0.0421
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0298 0.1116 0.1116
Loa Loa (eye worm) hypothetical protein 0.011 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Echinococcus multilocularis casein kinase I delta 0.021 0.0609 0.0625
Entamoeba histolytica hypothetical protein 0.0237 0.0762 0.2816
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.011 0.0028 0.0029
Echinococcus granulosus raf serine:threonine protein kinase 0.0145 0.0234 0.0234
Echinococcus granulosus netrin receptor unc 5 0.0166 0.0354 0.0359
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0049 0.0049
Loa Loa (eye worm) thioredoxin reductase 0.1768 0.9581 0.9581
Trypanosoma cruzi casein kinase, delta isoform, putative 0.021 0.0609 0.0635
Trichomonas vaginalis AGC family protein kinase 0.0333 0.1315 0.4495
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0605 0.2884 0.3003
Echinococcus granulosus expressed protein 0.016 0.0321 0.0324
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0333 0.1315 0.1315
Schistosoma mansoni serine/threonine protein kinase 0.042 0.1819 0.1898
Trichomonas vaginalis STE family protein kinase 0.0264 0.0918 0.314
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.067 0.0689
Echinococcus multilocularis dual specificity 0.027 0.095 0.0982
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.023 0.0723 0.0723
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0394 0.1668 0.1732
Schistosoma mansoni septate junction protein 0.0205 0.0579 0.0604
Trichomonas vaginalis mercuric reductase, putative 0.0613 0.2925 1
Brugia malayi Immunoglobulin domain containing protein 0.011 0.0028 0.0028
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.184 1 1
Echinococcus multilocularis neurogenic locus notch protein 0.0179 0.0425 0.0433
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0163 0.0333 0.0337
Loa Loa (eye worm) hypothetical protein 0.0219 0.0658 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0904 0.0943
Schistosoma mansoni tyrosine kinase 0.0355 0.1444 0.1507
Echinococcus multilocularis protein tyrosine kinase 0.0563 0.2643 0.275
Echinococcus granulosus serine:threonine protein kinase 3 0.05 0.2279 0.237
Echinococcus multilocularis hemicentin 1 0.0205 0.0579 0.0593
Loa Loa (eye worm) hypothetical protein 0.0361 0.1477 0.1477
Brugia malayi EGF-like domain containing protein 0.0222 0.0676 0.0676
Brugia malayi Variant SH3 domain containing protein 0.012 0.0088 0.0088
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0417 0.18 0.187
Schistosoma mansoni ste20-related kinase 0.0399 0.1696 0.177
Brugia malayi EGF-like domain containing protein 0.0179 0.0425 0.0425
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0579 0.0579
Entamoeba histolytica disulphide oxidoreductase, putative 0.0163 0.0333 0.1209
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0408 0.0426
Echinococcus multilocularis expressed protein 0.016 0.0321 0.0324
Echinococcus granulosus titin 0.0176 0.0408 0.0416
Echinococcus multilocularis cyclin dependent kinase 19 0.059 0.2798 0.2913
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0151 0.0266 0.0152
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.0521 0.178
Echinococcus granulosus Immunoglobulin subtype 0.011 0.0028 0.0018
Echinococcus multilocularis transfer RNA-Phe 0.0113 0.0049 0.004
Loa Loa (eye worm) hypothetical protein 0.0584 0.2759 0.2759
Schistosoma mansoni serine/threonine protein kinase 0.042 0.1819 0.1898
Giardia lamblia Kinase, NEK 0.0264 0.0918 0.2325
Schistosoma mansoni hypothetical protein 0.011 0.0028 0.0029
Schistosoma mansoni tyrosine kinase 0.0125 0.0116 0.0121
Schistosoma mansoni tyrosine kinase 0.0588 0.2782 0.2904
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0228 0.071 0.0731
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.011 0.0028 0.0029
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0159 0.031 0.0014
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0237 0.0762 0.0795
Schistosoma mansoni tyrosine kinase 0.0184 0.0455 0.0475
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0219 0.0658 0.0566
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0328 0.1121
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0162 0.0328 0.0217
Echinococcus granulosus CDC7 cell division cycle 7 0.0173 0.0396 0.0402
Brugia malayi Protein kinase domain containing protein 0.0173 0.0396 0.0396
Giardia lamblia Kinase, STE STE20 0.0163 0.0338 0.0106
Loa Loa (eye worm) TK protein kinase 0.0363 0.1489 0.1489
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0049 0.0049
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0219 0.0658 0.0687
Loa Loa (eye worm) AGC/NDR protein kinase 0.0313 0.1199 0.1199
Loa Loa (eye worm) hypothetical protein 0.012 0.0088 0.0088
Echinococcus multilocularis 0.0236 0.0756 0.0779
Echinococcus granulosus tyrosine protein kinase Src42A 0.0299 0.1119 0.1158
Entamoeba histolytica protein kinase, putative 0.0157 0.0302 0.1094
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0452 0.2 0.2
Loa Loa (eye worm) hypothetical protein 0.0252 0.0847 0.0847
Leishmania major NADH dehydrogenase, putative 0.0163 0.0333 0.0223
Onchocerca volvulus 0.033 0.1296 0.337
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Echinococcus multilocularis PAK box P21 Rho binding 0.0124 0.0109 0.0103
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Schistosoma mansoni protein kinase 0.0297 0.111 0.1159
Onchocerca volvulus 0.0271 0.096 0.2491
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.027 0.095 0.0876
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0139 0.0197 0.0197
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0309 0.1177 0.1229
Brugia malayi Protein kinase domain containing protein 0.0422 0.1829 0.1829
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Onchocerca volvulus 0.033 0.1296 0.337
Trichomonas vaginalis AGC family protein kinase 0.0219 0.0658 0.2249
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0613 0.2925 0.3053
Trypanosoma brucei polo-like protein kinase 0.0527 0.243 0.244
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0163 0.0333 0.0223
Plasmodium falciparum thioredoxin reductase 0.1768 0.9581 1
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.1116 0.1165
Onchocerca volvulus 0.0179 0.0425 0.1093
Schistosoma mansoni tyrosine kinase 0.0409 0.1755 0.1832
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0527 0.243 0.2528
Brugia malayi hypothetical protein 0.0128 0.0135 0.0135
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0299 0.1119 0.1158
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Echinococcus multilocularis casein kinase i 0.021 0.0609 0.0625
Echinococcus granulosus Immunoglobulin 0.011 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0113 0.0049 0.0049
Brugia malayi C1-like domain containing protein 0.0424 0.1837 0.1837
Loa Loa (eye worm) hypothetical protein 0.0206 0.0582 0.0582
Loa Loa (eye worm) hypothetical protein 0.0219 0.0656 0.0656
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0304 0.1149 0.0918
Giardia lamblia Glutamate synthase 0.0163 0.0333 0.0086
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0163 0.0333 0.0223
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0715 0.3518 0.3518
Schistosoma mansoni vam6/vps39 related 0.0219 0.0656 0.0684
Brugia malayi Fibronectin type III domain containing protein 0.0396 0.168 0.168
Brugia malayi Protein kinase domain containing protein 0.0128 0.0135 0.0135
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0298 0.1116 0.105
Brugia malayi cyclin-dependent kinase 9 0.0107 0.0011 0.0011
Brugia malayi putative serine/threonine kinase SADA gamma 0.0151 0.0266 0.0266
Onchocerca volvulus 0.0125 0.0118 0.0289
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0965 0.4956 0.5167
Trichomonas vaginalis CAMK family protein kinase 0.0527 0.243 0.8307
Brugia malayi Stress-activated protein kinase jnk-1 0.0515 0.2362 0.2362
Plasmodium falciparum casein kinase 1 0.021 0.0609 0.0514
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0313 0.1199 0.1241
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.2964
Onchocerca volvulus 0.0173 0.0396 0.1016
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0195 0.0521 0.0241
Echinococcus granulosus c4b binding protein beta chain 0.033 0.1296 0.1344
Onchocerca volvulus 0.033 0.1296 0.337
Trichomonas vaginalis AGC family protein kinase 0.0321 0.1243 0.425
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0195 0.0521 0.0521
Brugia malayi EGF-like domain containing protein 0.0179 0.0425 0.0425
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0113 0.0049 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.1163 0.6095 0.6095
Loa Loa (eye worm) cyclin C 0.0834 0.4202 0.4202
Echinococcus multilocularis neuroglian 0.0223 0.0681 0.0701
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0658 0.0687
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.011 0.0028 0.0018
Echinococcus granulosus Protein kinase C brain isozyme 0.0475 0.2131 0.2216
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Echinococcus granulosus cyclin dependent kinase 1 0.023 0.0723 0.0744
Loa Loa (eye worm) hypothetical protein 0.0222 0.0676 0.0676
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0613 0.2925 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0049 0.0049
Loa Loa (eye worm) CMGC/GSK protein kinase 0.025 0.0834 0.0834
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0579 0.0579
Schistosoma mansoni protein kinase 0.0847 0.4274 0.4462
Schistosoma mansoni cell adhesion molecule 0.0506 0.2312 0.2413
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Plasmodium vivax unspecified product 0.0194 0.0512 0.0232
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0166 0.0354 0.0358
Trichomonas vaginalis AGC family protein kinase 0.0228 0.071 0.2426
Echinococcus multilocularis mitogen activated protein kinase 0.0162 0.0328 0.0331
Giardia lamblia Kinase, NEK 0.0264 0.0918 0.2325
Echinococcus granulosus dual specificity 0.0237 0.0762 0.0785
Loa Loa (eye worm) hypothetical protein 0.0379 0.158 0.158
Onchocerca volvulus 0.0376 0.1563 0.4066
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0613 0.2925 0.2964
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0219 0.0656 0.0684
Echinococcus granulosus N chimaerin 0.0146 0.024 0.0239
Schistosoma mansoni septate junction protein 0.011 0.0028 0.0029
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0166 0.0354 0.0358
Schistosoma mansoni tyrosine kinase 0.0588 0.2782 0.2904
Schistosoma mansoni notch 0.0179 0.0425 0.0444
Echinococcus multilocularis roundabout 2 0.0223 0.0681 0.0701
Echinococcus granulosus serine:threonine protein kinase N2 0.0566 0.266 0.2768
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0107 0.0011 0.0011
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0163 0.0333 0.0337
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0613 0.2925 0.2803
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Trichomonas vaginalis apoptosis inducing factor, putative 0.0163 0.0333 0.1138
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0163 0.0333 0.1138
Entamoeba histolytica casein kinase, putative 0.021 0.0609 0.2243
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.033 0.1296 0.1296
Entamoeba histolytica hypothetical protein 0.0375 0.1559 0.5805
Loa Loa (eye worm) sex muscle abnormal protein 5 0.012 0.0088 0.0088
Echinococcus multilocularis serine threonine protein kinase 0.0393 0.166 0.1723
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.027 0.095 0.0876
Brugia malayi protein unc-22 0.0176 0.0408 0.0408
Brugia malayi Variant SH3 domain containing protein 0.012 0.0088 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0688 0.3358 0.3505
Echinococcus multilocularis tyrosine protein kinase 0.03 0.1127 0.1167
Loa Loa (eye worm) TK/EPH protein kinase 0.0223 0.0682 0.0682
Echinococcus multilocularis Glutaredoxin protein 5 0.0242 0.079 0.0814
Onchocerca volvulus 0.033 0.1296 0.337
Brugia malayi Protein kinase domain containing protein 0.0622 0.2982 0.2982
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0162 0.0328 0.0342
Echinococcus multilocularis hypothetical protein 0.0199 0.0545 0.0558
Loa Loa (eye worm) TK/FER protein kinase 0.0128 0.0135 0.0135
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0622 0.2982 0.2982
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0228 0.071 0.0445
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0396 0.1353
Onchocerca volvulus 0.033 0.1296 0.337
Schistosoma mansoni growth factor receptor-bound protein 0.0122 0.01 0.0104
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0219 0.0658 0.0658
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0163 0.0333 0.1138
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0163 0.0333 0.0223
Echinococcus multilocularis Immunoglobulin 0.0379 0.1577 0.1637
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0195 0.0521 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0313 0.1199 0.1251
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0156 0.0297 0.0185
Echinococcus multilocularis mitogen activated protein kinase 14 0.0309 0.1177 0.1219
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0157 0.0299 0.0301
Echinococcus multilocularis fibropellin Ia 0.0179 0.0425 0.0433
Brugia malayi Immunoglobulin domain containing protein 0.011 0.0028 0.0028
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Loa Loa (eye worm) programmed cell death 8 0.0163 0.0333 0.0333
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.011 0.0028 0.0029
Echinococcus multilocularis thioredoxin glutathione reductase 0.1768 0.9581 1
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0127 0.0128 0.0439
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0228 0.071 0.2622
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.027 0.095 0.095
Trichomonas vaginalis AGC family protein kinase 0.0333 0.1315 0.4495
Entamoeba histolytica protein kinase, putative 0.016 0.0321 0.1163
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0163 0.0338 0.0353
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0219 0.0656 0.0674
Brugia malayi Doublecortin family protein 0.0293 0.1084 0.1084
Echinococcus granulosus cGMP dependent protein kinase 0.0163 0.0334 0.0338
Brugia malayi Muscle positioning protein 4 0.0179 0.0425 0.0425
Echinococcus multilocularis roundabout 2 0.0223 0.0681 0.0701
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0163 0.0333 0.0223
Schistosoma mansoni septate junction protein 0.011 0.0028 0.0029
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0609 0.2081
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Brugia malayi serine/threonine-protein kinase 6 0.0228 0.071 0.071
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0477 0.2147 0.2147
Giardia lamblia Kinase, CMGC CLK 0.0298 0.1116 0.3079
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0433 0.1888 0.1962
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0179 0.0425 0.0425
Entamoeba histolytica protein kinase, putative 0.027 0.095 0.3524
Schistosoma mansoni nephrin 0.0223 0.0681 0.0711
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0904 0.0943
Schistosoma mansoni protein kinase 0.0715 0.3518 0.3672
Echinococcus granulosus tyrosine protein kinase Lyn 0.0361 0.1478 0.1534
Entamoeba histolytica protein kinase, putative 0.0139 0.0195 0.0689
Trypanosoma brucei cdc2-related kinase 3 0.023 0.0723 0.0635
Schistosoma mansoni tyrosine kinase 0.0269 0.0945 0.0987
Schistosoma mansoni glutamate synthase 0.0163 0.0333 0.0348
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0166 0.0354 0.0358
Echinococcus multilocularis protein jagged 2 0.0179 0.0425 0.0433
Brugia malayi intracellular kinase 0.025 0.0834 0.0834
Trypanosoma cruzi casein kinase, putative 0.021 0.0609 0.0635
Brugia malayi Cyclin C 0.0834 0.4202 0.4202
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0163 0.0333 0.0337
Loa Loa (eye worm) AUR protein kinase 0.0228 0.071 0.071
Entamoeba histolytica thioredoxin reductase, putative 0.0163 0.0333 0.1209
Toxoplasma gondii NADPH-glutathione reductase 0.0613 0.2925 0.2964
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.012 0.0088 0.0092
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1163 0.6095 0.6095
Echinococcus granulosus tyrosine protein kinase Fyn 0.0299 0.1119 0.1158
Loa Loa (eye worm) hypothetical protein 0.0179 0.0425 0.0425
Brugia malayi Casein kinase II, alpha chain 0.0194 0.0512 0.0512
Brugia malayi Tyrosine-protein kinase abl-1 0.0184 0.0455 0.0455
Schistosoma mansoni serine/threonine protein kinase 0.027 0.095 0.0992
Loa Loa (eye worm) hypothetical protein 0.0128 0.0135 0.0135
Brugia malayi ephrin receptor 1 precursor 0.0123 0.0103 0.0103
Echinococcus granulosus casein kinase ii subunit alpha 0.0194 0.0512 0.0524
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0243 0.0799 0.0824
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0163 0.0333 0.0337
Echinococcus granulosus c src tyrosine kinase 0.0184 0.0455 0.0464
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0613 0.2925 0.2803
Echinococcus multilocularis neurogenic locus notch protein 0.0179 0.0425 0.0433
Brugia malayi Protein kinase domain containing protein 0.0622 0.2982 0.2982
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0162 0.0328 0.0217
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0433 0.1888 0.1888
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0428 0.1861 0.1934
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0264 0.0918 0.0669
Schistosoma mansoni basigin related 0.011 0.0028 0.0029
Entamoeba histolytica cell division protein kinase 2, putative 0.0238 0.0768 0.2839
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0723 0.2472
Brugia malayi Thioredoxin reductase 0.1768 0.9581 0.9581
Schistosoma mansoni serine/threonine protein kinase 0.0566 0.266 0.2776
Loa Loa (eye worm) TK/ALK protein kinase 0.0297 0.1109 0.1109
Brugia malayi hypothetical protein 0.033 0.1296 0.1296
Brugia malayi Temporarily assigned gene name protein 59 0.0252 0.085 0.085
Onchocerca volvulus 0.0219 0.0656 0.1695
Treponema pallidum NADH oxidase 0.0613 0.2925 1
Schistosoma mansoni cell adhesion molecule 0.011 0.0028 0.0029
Onchocerca volvulus 0.0128 0.0135 0.0333
Echinococcus granulosus fibroblast growth factor receptor 4 0.0355 0.1444 0.1498
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.0681 0.2329
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0688 0.3358 0.3497
Echinococcus granulosus mitogen activated protein kinase 11 0.0309 0.1177 0.1219
Onchocerca volvulus 0.0113 0.0049 0.0109
Giardia lamblia Kinase, AGC AKT 0.0227 0.0704 0.1503
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0613 0.2925 0.3053
Echinococcus multilocularis protein jagged 1 0.0179 0.0425 0.0433
Brugia malayi map kinase activated protein kinase protein 2 0.0769 0.3827 0.3827
Toxoplasma gondii casein kinase I 0.021 0.0609 0.0514
Echinococcus multilocularis NCK adaptor protein 0.0122 0.01 0.0093
Schistosoma mansoni tyrosine kinase 0.0563 0.2643 0.2759
Entamoeba histolytica protein kinase, putative 0.025 0.0834 0.3088
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0223 0.0681 0.0701
Schistosoma mansoni protein kinase 0.043 0.1875 0.1957
Loa Loa (eye worm) hypothetical protein 0.0237 0.0761 0.0761
Schistosoma mansoni basigin related 0.011 0.0028 0.0029
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0163 0.0333 0.0223
Echinococcus granulosus fibropellin Ia 0.0179 0.0425 0.0433
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0769 0.3827 0.3988
Brugia malayi Protein kinase domain containing protein 0.0569 0.2677 0.2677
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0219 0.0656 0.0564
Echinococcus multilocularis cyclin 0.0417 0.18 0.187
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0769 0.3827 0.3988
Brugia malayi GCC2 and GCC3 family protein 0.0508 0.2325 0.2325
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Echinococcus multilocularis neuroglian 0.0474 0.2127 0.2212
Echinococcus granulosus protein kinase C gamma type 0.0393 0.166 0.1723
Echinococcus multilocularis epidermal growth factor receptor 0.0679 0.3306 0.3444
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0613 0.2925 0.2803
Brugia malayi RhoGAP domain containing protein 0.0146 0.024 0.024
Echinococcus multilocularis basement membrane specific heparan sulfate 0.011 0.0028 0.0018
Echinococcus multilocularis death associated protein kinase 1 0.0868 0.4395 0.4582
Entamoeba histolytica protein kinase, putative 0.0198 0.0535 0.1966
Loa Loa (eye worm) Notch2 0.0179 0.0425 0.0425
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0106 0.0007 0.0007
Leishmania major casein kinase, putative 0.021 0.0609 0.0514
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0436 0.0455
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0281 0.1016 0.1051
Plasmodium vivax glycogen synthase kinase 3, putative 0.025 0.0834 0.0579
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0579 0.0579
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0613 0.2925 0.3046
Plasmodium vivax apical sushi protein, putative 0.033 0.1296 0.1076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0681 0.0681
Loa Loa (eye worm) hypothetical protein 0.033 0.1296 0.1296
Leishmania major casein kinase II, putative 0.0194 0.0512 0.0413
Echinococcus multilocularis netrin receptor unc 5 0.0166 0.0354 0.0359
Brugia malayi Cyclin, N-terminal domain containing protein 0.0417 0.18 0.18
Schistosoma mansoni hypothetical protein 0.011 0.0028 0.0029
Brugia malayi Sex muscle abnormal protein 5 0.012 0.0088 0.0088
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0391 0.1646 0.1709
Schistosoma mansoni hypothetical protein 0.0163 0.0333 0.0348
Echinococcus multilocularis titin 0.0176 0.0408 0.0416
Entamoeba histolytica PH domain containing protein kinase, putative 0.0319 0.1235 0.459
Brugia malayi hypothetical protein 0.011 0.0028 0.0028
Entamoeba histolytica protein kinase, putative 0.0195 0.0521 0.1912
Trypanosoma brucei hypothetical protein, conserved 0.0163 0.0333 0.0223
Loa Loa (eye worm) TK/FAK protein kinase 0.0569 0.2677 0.2677
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0613 0.2925 0.2964
Echinococcus granulosus tyrosine kinase 0.0243 0.0799 0.0824
Schistosoma mansoni septate junction protein 0.0205 0.0579 0.0604
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.025 0.0834 0.0871
Loa Loa (eye worm) hypothetical protein 0.0125 0.0118 0.0118
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0715 0.3518 0.3665
Plasmodium vivax calcium-dependent protein kinase, putative 0.0195 0.0521 0.0241
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0163 0.0333 0.0348
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0266 0.0277
Schistosoma mansoni serine/threonine kinase 0.0313 0.1199 0.1251
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0195 0.0521 0.0421
Giardia lamblia Kinase, CMGC SRPK 0.016 0.0321 0.0039
Entamoeba histolytica protein kinase 2, putative 0.0304 0.1149 0.4269
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0318 0.123 0.123
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Onchocerca volvulus 0.025 0.0834 0.2162
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0127 0.0131 0.0131
Brugia malayi Hr1 repeat family protein 0.0566 0.266 0.266
Brugia malayi Protein kinase domain containing protein 0.0715 0.3518 0.3518
Trypanosoma cruzi hypothetical protein, conserved 0.0163 0.0333 0.0348
Trichomonas vaginalis AGC family protein kinase 0.0228 0.071 0.2426
Giardia lamblia Kinase, CK1 Casein kinase 0.021 0.0609 0.1141
Plasmodium vivax serine/threonine protein kinase, putative 0.016 0.0321 0.0025
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0162 0.0328 0.0342
Echinococcus multilocularis Immunoglobulin 0.011 0.0028 0.0018
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.042 0.1819 0.1889
Trypanosoma brucei protein kinase, putative 0.025 0.0834 0.0753
Plasmodium falciparum glutathione reductase 0.0613 0.2925 0.2964
Echinococcus granulosus tyrosine protein kinase 0.03 0.1127 0.1167
Brugia malayi Protein kinase domain containing protein 0.0688 0.3358 0.3358
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0298 0.1116 0.105
Echinococcus multilocularis cyclin dependent kinase 5 0.023 0.0723 0.0744
Schistosoma mansoni cell adhesion molecule 0.0223 0.0681 0.0711
Trichomonas vaginalis CMGC family protein kinase 0.027 0.095 0.3249
Schistosoma mansoni roundabout 0.0205 0.0579 0.0604
Trichomonas vaginalis AGC family protein kinase 0.057 0.2678 0.9153
Echinococcus granulosus neurogenic locus notch protein 0.0179 0.0425 0.0433
Echinococcus granulosus casein kinase I gamma 0.0415 0.1787 0.1857
Trypanosoma cruzi casein kinase II, putative 0.0194 0.0512 0.0535
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0195 0.0521 0.0533
Loa Loa (eye worm) hypothetical protein 0.011 0.0028 0.0028
Schistosoma mansoni protein kinase 0.0228 0.071 0.0741
Loa Loa (eye worm) TK/ABL protein kinase 0.0128 0.0135 0.0135
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.066 0.3199 0.3199
Echinococcus granulosus neurogenic locus protein delta 0.0179 0.0425 0.0433
Brugia malayi notch-like transmembrane receptor 0.0179 0.0425 0.0425
Brugia malayi Protein kinase domain containing protein 0.03 0.1127 0.1127
Echinococcus granulosus casein kinase I alpha 0.021 0.0609 0.0625
Echinococcus multilocularis mitogen activated protein kinase 11 0.0309 0.1177 0.1219
Brugia malayi Protein kinase domain containing protein 0.0237 0.0762 0.0762
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0151 0.0266 0.0277
Echinococcus granulosus tyrosine protein kinase shark 0.0339 0.135 0.1399
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0396 0.1353
Echinococcus multilocularis calcium dependent protein kinase 0.0133 0.0161 0.0157
Loa Loa (eye worm) hypothetical protein 0.0271 0.096 0.096
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0162 0.0328 0.0342
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.011 0.0028 0.0029
Toxoplasma gondii CMGC kinase, CK2 family 0.0194 0.0512 0.0413
Toxoplasma gondii selenide, water dikinase 0.0163 0.0333 0.0223
Trypanosoma cruzi NADH dehydrogenase, putative 0.0163 0.0333 0.0348
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0681 0.0681
Echinococcus granulosus hypothetical protein 0.0236 0.0756 0.0779
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0219 0.0658 0.0687
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0299 0.1119 0.1158
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0194 0.0512 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0157 0.0302 0.1034
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0328 0.0342
Loa Loa (eye worm) hypothetical protein 0.0584 0.2763 0.2763
Schistosoma mansoni hypothetical protein 0.011 0.0028 0.0029
Echinococcus multilocularis neurogenic locus protein delta 0.0179 0.0425 0.0433
Echinococcus granulosus casein kinase I alpha 0.021 0.0609 0.0625
Echinococcus granulosus serine:threonine kinase SAD 1 0.0151 0.0266 0.0267
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0613 0.2925 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0658 0.0676
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0163 0.0333 0.1138
Schistosoma mansoni hypothetical protein 0.0179 0.0425 0.0444
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0379 0.1577 0.1646
Trichomonas vaginalis STE family protein kinase 0.0166 0.0354 0.1208
Trypanosoma brucei aurora B kinase 0.0228 0.071 0.0621
Loa Loa (eye worm) AGC/PKA protein kinase 0.0219 0.0658 0.0658
Schistosoma mansoni tyrosine kinase 0.0473 0.2122 0.2215
Echinococcus granulosus activin receptor type 0.0126 0.0122 0.0117
Brugia malayi serine/threonine protein kinase 6 0.0228 0.071 0.071
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0219 0.0658 0.0389
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0688 0.3358 0.3358
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0266 0.0908
Loa Loa (eye worm) hypothetical protein 0.0584 0.2759 0.2759
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0266 0.0277
Entamoeba histolytica cyclin C, putative 0.0423 0.1835 0.6839
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0243 0.0799 0.0824
Echinococcus multilocularis cyclin dependent kinase 1 0.023 0.0723 0.0744
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.011 0.0028 0.0028
Echinococcus granulosus neuroglian 0.0223 0.0681 0.0701
Echinococcus multilocularis cyclin dependent kinase 0.023 0.0723 0.0744
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0163 0.0333 0.1209
Echinococcus granulosus tyrosine protein kinase Fyn 0.0299 0.1119 0.1158
Giardia lamblia Kinase, CMGC GSK 0.025 0.0834 0.2003
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0512 0.1752
Giardia lamblia Kinase, CMGC MAPK 0.0162 0.0328 0.0066
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0688 0.3358 0.8759
Brugia malayi Immunoglobulin I-set domain containing protein 0.011 0.0031 0.0031
Brugia malayi Protein kinase domain containing protein 0.0128 0.0135 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0396 0.1353
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.025 0.0834 0.0753
Schistosoma mansoni titin 0.0113 0.0049 0.0051
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0613 0.2925 0.2925
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0219 0.0658 0.0687
Brugia malayi Prion-like- 0.0205 0.0579 0.0579
Echinococcus multilocularis neurogenic locus notch protein 4 0.0179 0.0425 0.0433
Onchocerca volvulus Slit protein homolog 0.0222 0.0676 0.1747
Schistosoma mansoni hypothetical protein 0.0199 0.0545 0.0568
Trypanosoma brucei casein kinase I, isoform 2 0.021 0.0609 0.0514

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 % Percent reduction of cataleptic effect in rat upon dosing at 3 mg/kg; Not tested ChEMBL. 15982882
Inhibition 0 % Percent inhibition of hERG by rubidium efflux FLIPR assay at concentration of 5 ug/mL; Not tested ChEMBL. 15982882
Ki (binding) = 5.7 nM Inhibitory constant against Adenosine A2A receptor using [3H]-SCH-58,261 as radio ligand ChEMBL. 15982882
Selectivity (binding) = 66 nM Selectivity between A1 and A2A receptors ChEMBL. 15982882

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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