Detailed information for compound 313031

Basic information

Technical information
  • TDR Targets ID: 313031
  • Name: 2-hydroxy-5-[[2-[(6-methoxy-1H-benzimidazol-2 -yl)sulfanyl]acetyl]amino]benzoic acid
  • MW: 373.383 | Formula: C17H15N3O5S
  • H donors: 4 H acceptors: 5 LogP: 2.93 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)nc([nH]2)SCC(=O)Nc1ccc(c(c1)C(=O)O)O
  • InChi: 1S/C17H15N3O5S/c1-25-10-3-4-12-13(7-10)20-17(19-12)26-8-15(22)18-9-2-5-14(21)11(6-9)16(23)24/h2-7,21H,8H2,1H3,(H,18,22)(H,19,20)(H,23,24)
  • InChiKey: KPGNACCOMWZKTJ-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-hydroxy-5-[[2-[(6-methoxy-1H-benzimidazol-2-yl)thio]-1-oxoethyl]amino]benzoic acid
  • 2-hydroxy-5-[2-[(6-methoxy-1H-benzimidazol-2-yl)sulfanyl]ethanoylamino]benzoic acid
  • 2-hydroxy-5-[[2-[(6-methoxy-1H-benzimidazol-2-yl)thio]acetyl]amino]benzoic acid
  • STK213810
  • AIDS-226955
  • AIDS226955
  • Benzoic acid, 2-hydroxy-5-[[[(5-methoxy-1H-benzimidazol-2-yl)thio]acetyl]amino]-
  • EU-0014708
  • Oprea1_146985

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0232 0.0244 0.109
Schistosoma mansoni serine/threonine protein kinase 0.0737 0.1579 0.1579
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Plasmodium falciparum protein kinase 5 0.027 0.0344 0.032
Schistosoma mansoni hypothetical protein 0.0181 0.0111 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0613 0.1251 0.1251
Toxoplasma gondii rhoptry neck protein RON9 0.0732 0.1567 0.1545
Echinococcus granulosus thioredoxin glutathione reductase 0.3926 1 1
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0315 0.0465 0.0441
Echinococcus granulosus serine:threonine protein kinase MARK2 0.049 0.0926 0.0926
Brugia malayi MAP kinase sur-1 0.019 0.0134 0.0134
Brugia malayi Protein kinase domain containing protein 0.0204 0.017 0.017
Echinococcus multilocularis dual specificity 0.0315 0.0465 0.0465
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0178 0.0101 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0686 0.0686
Entamoeba histolytica protein kinase , putative 0.0267 0.0337 0.1539
Trichomonas vaginalis CAMK family protein kinase 0.0229 0.0237 0.0682
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0192 0.014 0.0115
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.136 0.3225 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0247 0.0283 0.0283
Toxoplasma gondii histone kinase SNF1, putative 0.0178 0.0101 0.0076
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.136 0.3225 0.3208
Echinococcus multilocularis fibropellin Ia 0.0397 0.068 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0799 0.1743 0.1743
Trichomonas vaginalis STE family protein kinase 0.0195 0.0148 0.0405
Entamoeba histolytica protein kinase, putative 0.0663 0.1382 0.6576
Brugia malayi casein kinase 1, delta 0.0247 0.0283 0.0283
Schistosoma mansoni titin 0.0181 0.0111 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Giardia lamblia Thioredoxin reductase 0.0361 0.0586 0.1472
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0217 0.0206 0.0206
Echinococcus granulosus nervana 2 0.028 0.0372 0.0372
Echinococcus multilocularis neuroglian 0.042 0.074 0.074
Schistosoma mansoni tyrosine kinase 0.0681 0.1431 0.1431
Brugia malayi EGF-like domain containing protein 0.0397 0.068 0.068
Echinococcus granulosus serine:threonine protein kinase N2 0.0659 0.1373 0.1373
Brugia malayi Protein kinase domain containing protein 0.1017 0.2318 0.2318
Plasmodium falciparum calcium-dependent protein kinase 3 0.0229 0.0237 0.0212
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.044 0.044
Schistosoma mansoni protein kinase 0.0501 0.0956 0.0956
Entamoeba histolytica protein kinase, putative 0.0663 0.1382 0.6576
Echinococcus multilocularis casein kinase I delta 0.0247 0.0283 0.0283
Onchocerca volvulus 0.0662 0.1381 0.6327
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0253 0.0301 0.0301
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0166 0.0166
Brugia malayi Protein kinase domain containing protein 0.0437 0.0787 0.0787
Echinococcus granulosus cGMP dependent protein kinase 1 0.0191 0.0138 0.0138
Echinococcus granulosus Glutaredoxin protein 5 0.028 0.0372 0.0372
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.0963 0.0963
Giardia lamblia Kinase, STE STE20 0.0192 0.014 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0533 0.104 0.104
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1653 0.3999 0.3999
Schistosoma mansoni serine/threonine protein kinase 0.0365 0.0597 0.0597
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0361 0.0586 0.0562
Echinococcus granulosus neural cadherin 0.0397 0.068 0.068
Schistosoma mansoni hypothetical protein 0.0181 0.0111 0.0111
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0361 0.0585 0.0585
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.136 0.3225 0.3208
Echinococcus granulosus Immunoglobulin 0.0716 0.1522 0.1522
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0492 0.0932 0.0932
Trichomonas vaginalis STE family protein kinase 0.0195 0.0148 0.0405
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.028 0.0372 0.0372
Echinococcus granulosus peroxidasin 0.0399 0.0687 0.0687
Echinococcus multilocularis protein kinase c iota type 0.0648 0.1343 0.1343
Echinococcus multilocularis titin 0.0181 0.0111 0.0111
Echinococcus granulosus NDR protein kinase 0.0365 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0399 0.0687 0.0687
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0202 0.0166 0.0166
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0192 0.014 0.0587
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0732 0.1567 0.1567
Brugia malayi serine/threonine kinase 12 0.0267 0.0337 0.0337
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Entamoeba histolytica protein kinase, putative 0.0189 0.013 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0894 0.1992 0.1992
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0192 0.014 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0465 0.1393
Brugia malayi Immunoglobulin I-set domain containing protein 0.0217 0.0206 0.0206
Schistosoma mansoni tyrosine kinase 0.0475 0.0886 0.0886
Leishmania major hypothetical protein, conserved 0.0361 0.0586 0.0562
Brugia malayi Protein kinase domain containing protein 0.0661 0.1377 0.1377
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0799 0.1743 0.1743
Plasmodium vivax serine/threonine kinase-1, putative 0.0349 0.0553 0.044
Schistosoma mansoni septate junction protein 0.0217 0.0206 0.0206
Echinococcus multilocularis cyclin 0.0918 0.2058 0.2058
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0134 0.0362
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Echinococcus multilocularis casein kinase I alpha 0.0247 0.0283 0.0283
Schistosoma mansoni tyrosine kinase 0.0318 0.0473 0.0473
Giardia lamblia NADH oxidase lateral transfer candidate 0.136 0.3225 1
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0347 0.0548 0.0548
Echinococcus granulosus epidermal growth factor receptor 0.0787 0.1711 0.1711
Echinococcus multilocularis tyrosine kinase 0.0149 0.0025 0.0025
Trypanosoma cruzi NADH dehydrogenase, putative 0.0361 0.0586 0.0562
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0412 0.072 0.072
Onchocerca volvulus Netrin receptor homolog 0.0247 0.0284 0.1257
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0349 0.0553 0.0529
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0227 0.0232 0.0116
Echinococcus multilocularis mitogen activated protein kinase 11 0.0361 0.0585 0.0585
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Brugia malayi Protein kinase domain containing protein 0.0319 0.0474 0.0474
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0496 0.0943 0.0943
Schistosoma mansoni serine/threonine protein kinase 0.0463 0.0855 0.0855
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1121 0.2592 0.2592
Echinococcus multilocularis tyrosine protein kinase otk 0.0399 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Schistosoma mansoni cell adhesion molecule 0.0954 0.2151 0.2151
Brugia malayi Protein kinase domain containing protein 0.0185 0.0121 0.0121
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0292 0.0403 0.0403
Brugia malayi Thioredoxin reductase 0.3926 1 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0686 0.0686
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0397 0.068 0.068
Leishmania major hypothetical protein, conserved 0.0361 0.0586 0.0562
Loa Loa (eye worm) hypothetical protein 0.0149 0.0025 0.0025
Echinococcus multilocularis nervana 2 0.028 0.0372 0.0372
Giardia lamblia Kinase, NEK 0.0309 0.0448 0.1026
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0195 0.0148 0.0148
Trypanosoma brucei polo-like protein kinase 0.0613 0.1251 0.1229
Loa Loa (eye worm) animal heme peroxidase 0.0181 0.0111 0.0111
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0191 0.0138 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0455 0.0835 0.0835
Schistosoma mansoni notch 0.0397 0.068 0.068
Schistosoma mansoni slit 0.0182 0.0113 0.0113
Schistosoma mansoni tyrosine kinase 0.0549 0.1081 0.1081
Schistosoma mansoni hypothetical protein 0.0217 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis nervana 2 0.028 0.0372 0.0372
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0267 0.0337 0.0337
Loa Loa (eye worm) AUR protein kinase 0.0267 0.0337 0.0337
Onchocerca volvulus 0.0149 0.0025 0.0057
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Onchocerca volvulus 0.0397 0.068 0.3085
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0361 0.0586 0.2737
Loa Loa (eye worm) hypothetical protein 0.0815 0.1784 0.1784
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Brugia malayi Delta serrate ligand family protein 0.0397 0.068 0.068
Trichomonas vaginalis STE family protein kinase 0.0195 0.0148 0.0405
Brugia malayi Peroxidasin 0.0399 0.0687 0.0687
Entamoeba histolytica protein kinase domain containing protein 0.0227 0.0232 0.1033
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.136 0.3225 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Giardia lamblia Kinase, AGC AKT 0.0266 0.0334 0.0657
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0181 0.0111 0.0111
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0181 0.0111 0.0111
Schistosoma mansoni glutamate synthase 0.0361 0.0586 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0324 0.0487 0.0487
Echinococcus multilocularis tyrosine protein kinase Blk 0.0282 0.0378 0.0378
Toxoplasma gondii CMGC kinase, CK2 family 0.0227 0.0232 0.0208
Onchocerca volvulus 0.0732 0.1567 0.7186
Brugia malayi Animal haem peroxidase family protein 0.0181 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0399 0.0686 0.0686
Brugia malayi Prion-like- 0.0181 0.0111 0.0111
Echinococcus granulosus tyrosine protein kinase otk 0.0399 0.0686 0.0686
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.136 0.3225 0.3208
Echinococcus granulosus cyclin dependent kinase 1 0.027 0.0344 0.0344
Brugia malayi pregnancy-associated plasma protein-A 0.0732 0.1567 0.1567
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0195 0.0148 0.0148
Schistosoma mansoni notch 0.0397 0.068 0.068
Brugia malayi phosphoinositide-dependent protein kinase I 0.0185 0.0121 0.0121
Trypanosoma cruzi casein kinase, putative 0.0247 0.0283 0.0259
Plasmodium falciparum glycogen synthase kinase 3 0.0292 0.0403 0.0379
Schistosoma mansoni tyrosine kinase 0.0457 0.0838 0.0838
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0238 0.0261 0.0261
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0347 0.0548 0.0548
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0217 0.0206 0.0206
Loa Loa (eye worm) CDC7 protein kinase 0.0204 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.042 0.074 0.074
Echinococcus granulosus nervana 2 0.028 0.0372 0.0372
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.136 0.3225 0.3208
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.017 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0202 0.0166 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0185 0.0185
Echinococcus granulosus neurogenic locus notch protein 0.0397 0.068 0.068
Echinococcus multilocularis notch 0.0397 0.068 0.068
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0217 0.0206 0.0206
Echinococcus multilocularis neurogenic locus notch protein 0.0397 0.068 0.068
Echinococcus multilocularis N chimaerin 0.017 0.008 0.008
Brugia malayi Immunoglobulin domain containing protein 0.0217 0.0206 0.0206
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0533 0.104 0.104
Trichomonas vaginalis CAMK family protein kinase 0.0613 0.1251 0.3844
Trypanosoma cruzi casein kinase, putative 0.0247 0.0283 0.0259
Entamoeba histolytica protein kinase domain containing protein 0.0267 0.0337 0.1539
Brugia malayi Immunoglobulin I-set domain containing protein 0.1715 0.416 0.416
Echinococcus granulosus casein kinase ii subunit alpha 0.0227 0.0232 0.0232
Brugia malayi Protein kinase domain containing protein 0.0725 0.1546 0.1546
Brugia malayi SH2 domain containing protein 0.0496 0.0943 0.0943
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Loa Loa (eye worm) thioredoxin reductase 0.3926 1 1
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.046 0.0846 0.0846
Giardia lamblia Kinase, CMGC CK2 0.0227 0.0232 0.0329
Echinococcus multilocularis cyclin dependent kinase 0.027 0.0344 0.0344
Plasmodium vivax unspecified product 0.0227 0.0232 0.0116
Loa Loa (eye worm) AGC/PKN protein kinase 0.0659 0.1373 0.1373
Schistosoma mansoni cell adhesion molecule 0.0202 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0399 0.0686 0.0686
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0361 0.0586 0.0586
Brugia malayi Casein kinase II, alpha chain 0.0227 0.0232 0.0232
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0086 0.0086
Echinococcus granulosus nephrin 0.0202 0.0166 0.0166
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Entamoeba histolytica casein kinase 1, putative 0.0247 0.0283 0.1279
Onchocerca volvulus 0.0732 0.1567 0.7186
Schistosoma mansoni serine/threonine protein kinase 0.0315 0.0465 0.0465
Onchocerca volvulus 0.0202 0.0166 0.0709
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0349 0.0553 0.0529
Giardia lamblia Kinase, NEK 0.0309 0.0448 0.1026
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0328 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0202 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0365 0.0597 0.0597
Brugia malayi Protein kinase domain containing protein 0.0799 0.1743 0.1743
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0229 0.0237 0.0212
Echinococcus granulosus aurora kinase A 0.0267 0.0337 0.0337
Brugia malayi serine/threonine-protein kinase plk-2 0.0613 0.1251 0.1251
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0202 0.0166 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Trichomonas vaginalis CMGC family protein kinase 0.0292 0.0403 0.1201
Onchocerca volvulus 0.0182 0.0113 0.0464
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0277 0.0365 0.034
Trypanosoma cruzi polo-like protein kinase, putative 0.0613 0.1251 0.1229
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0259 0.0316 0.0316
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Trypanosoma brucei cdc2-related kinase 1 0.027 0.0344 0.032
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.027 0.0344 0.032
Loa Loa (eye worm) AUR protein kinase 0.0267 0.0337 0.0337
Loa Loa (eye worm) hypothetical protein 0.0399 0.0686 0.0686
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0361 0.0586 0.0562
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0361 0.0586 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0101 0.0101
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Entamoeba histolytica disulphide oxidoreductase, putative 0.0361 0.0586 0.2737
Trichomonas vaginalis CK1 family protein kinase 0.0247 0.0283 0.0827
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Schistosoma mansoni tyrosine kinase 0.0654 0.1359 0.1359
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0178 0.0101 0.0076
Leishmania major protein kinase A catalytic subunit isoform 1 0.0256 0.031 0.0285
Echinococcus granulosus tyrosine kinase 0.0282 0.0378 0.0378
Echinococcus granulosus fibropellin Ia 0.0397 0.068 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Schistosoma mansoni protein kinase 0.0984 0.223 0.223
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Schistosoma mansoni tyrosine kinase 0.0213 0.0195 0.0195
Entamoeba histolytica protein kinase, putative 0.0267 0.0337 0.1539
Schistosoma mansoni hypothetical protein 0.0217 0.0206 0.0206
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0166 0.0166
Echinococcus multilocularis protein kinase c epsilon type 0.0463 0.0855 0.0855
Entamoeba histolytica cell division protein kinase 2, putative 0.0287 0.0389 0.1788
Schistosoma mansoni basigin related 0.0217 0.0206 0.0206
Onchocerca volvulus 0.0708 0.1501 0.6883
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0168 0.0075 0.0075
Brugia malayi Protein kinase domain containing protein 0.0439 0.0793 0.0793
Echinococcus multilocularis Glutaredoxin protein 5 0.028 0.0372 0.0372
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0526 0.102 0.102
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0229 0.0237 0.0237
Schistosoma mansoni tyrosine kinase 0.0681 0.1431 0.1431
Loa Loa (eye worm) hypothetical protein 0.027 0.0344 0.0344
Schistosoma mansoni septate junction protein 0.0397 0.068 0.068
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0465 0.1393
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0755 0.1626 0.1626
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.027 0.0344 0.0344
Brugia malayi Protein kinase domain containing protein 0.0189 0.013 0.013
Echinococcus granulosus dual specificity 0.0315 0.0465 0.0465
Brugia malayi RhoGAP domain containing protein 0.017 0.008 0.008
Giardia lamblia Kinase, CMGC GSK 0.0292 0.0403 0.0881
Brugia malayi Serine/threonine-protein kinase SULU 0.0504 0.0963 0.0963
Echinococcus multilocularis Immunoglobulin 0.0716 0.1522 0.1522
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0229 0.0237 0.012
Schistosoma mansoni roundabout 0.0399 0.0686 0.0686
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0282 0.0378 0.0378
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0247 0.0283 0.0259
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.049 0.0926 0.0926
Echinococcus multilocularis Immunoglobulin 0.0217 0.0206 0.0206
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.019 0.0134 0.0109
Echinococcus multilocularis CDC7 cell division cycle 7 0.0204 0.017 0.017
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0361 0.0586 0.0586
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0918 0.2058 0.2058
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0361 0.0586 0.0562
Echinococcus multilocularis 0.0218 0.0209 0.0209
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0256 0.031 0.0285
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0519 0.1002 0.1002
Echinococcus granulosus insulin receptor 0.0681 0.1431 0.1431
Onchocerca volvulus 0.0732 0.1567 0.7186
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0256 0.031 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0349 0.0553 0.0553
Entamoeba histolytica protein kinase 2, putative 0.0355 0.0571 0.2663
Loa Loa (eye worm) hypothetical protein 0.0259 0.0316 0.0316
Trichomonas vaginalis AGC family protein kinase 0.0389 0.0659 0.1997
Echinococcus granulosus protein jagged 2 0.0397 0.068 0.068
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Brugia malayi Protein kinase domain containing protein 0.0372 0.0615 0.0615
Mycobacterium tuberculosis Probable oxidoreductase 0.136 0.3225 0.2803
Loa Loa (eye worm) hypothetical protein 0.0245 0.0279 0.0279
Brugia malayi hypothetical protein 0.0736 0.1577 0.1577
Onchocerca volvulus Neurogenic locus notch homolog 0.0397 0.068 0.3085
Schistosoma mansoni tyrosine kinase 0.0213 0.0195 0.0195
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0725 0.1546 0.1546
Schistosoma mansoni ste20-related kinase 0.0465 0.0861 0.0861
Schistosoma mansoni tyrosine kinase 0.0475 0.0886 0.0886
Trypanosoma brucei trypanothione reductase 0.3926 1 1
Echinococcus multilocularis mitogen activated protein kinase 14 0.0361 0.0585 0.0585
Echinococcus multilocularis insulin receptor 0.0681 0.1431 0.1431
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0361 0.0586 0.0586
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.028 0.0372 0.0372
Schistosoma mansoni titin 0.0181 0.0111 0.0111
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0255 0.0306 0.0306
Trypanosoma cruzi polo-like protein kinase, putative 0.0613 0.1251 0.1229
Brugia malayi Kinase associated domain 1 family protein 0.0231 0.0242 0.0242
Brugia malayi Cam kinase protein 1 0.0229 0.0237 0.0237
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0256 0.031 0.0285
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Onchocerca volvulus 0.0149 0.0025 0.0057
Echinococcus granulosus cyclin dependent kinase 19 0.1238 0.2901 0.2901
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0266 0.0334 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.013 0.013
Giardia lamblia Kinase, CK1 Casein kinase 0.0247 0.0283 0.0494
Schistosoma mansoni titin 0.0277 0.0364 0.0364
Loa Loa (eye worm) projectin 0.0202 0.0166 0.0166
Leishmania major protein kinase, putative 0.0349 0.0553 0.0529
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0191 0.0138 0.0138
Echinococcus multilocularis myosin iiia 0.0192 0.014 0.014
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0253 0.0301 0.0277
Entamoeba histolytica PH domain containing protein kinase, putative 0.0274 0.0355 0.1624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0217 0.0206 0.0206
Entamoeba histolytica protein kinase, putative 0.0315 0.0465 0.2154
Giardia lamblia Kinase, CMGC GSK 0.0292 0.0403 0.0881
Echinococcus multilocularis insulin growth factor binding 0.0181 0.0111 0.0111
Echinococcus granulosus twitchin 0.0972 0.22 0.22
Schistosoma mansoni titin 0.0399 0.0686 0.0686
Brugia malayi Protein kinase domain containing protein 0.0681 0.1431 0.1431
Echinococcus multilocularis rac serine:threonine kinase 0.0372 0.0616 0.0616
Plasmodium vivax glycogen synthase kinase 3, putative 0.0292 0.0403 0.0289
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0465 0.1393
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0361 0.0586 0.2737
Trichomonas vaginalis CMGC family protein kinase 0.0349 0.0553 0.1667
Loa Loa (eye worm) hypothetical protein 0.0239 0.0262 0.0262
Echinococcus multilocularis Immunoglobulin 0.0217 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0256 0.031 0.031
Echinococcus granulosus protein kinase c epsilon type 0.0463 0.0855 0.0855
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0831 0.1828 0.1828
Onchocerca volvulus 0.0204 0.017 0.073
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0347 0.055 0.055
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0361 0.0586 0.0562
Echinococcus granulosus tyrosine protein kinase 0.0349 0.0553 0.0553
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.136 0.3225 0.3208
Loa Loa (eye worm) one IG domain family member 0.0181 0.0111 0.0111
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0725 0.1546 0.1546
Echinococcus multilocularis dual specificity 0.0315 0.0465 0.0465
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0229 0.0237 0.0212
Echinococcus granulosus protein jagged 1 0.0397 0.068 0.068
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0493 0.0936 0.0936
Onchocerca volvulus 0.0732 0.1567 0.7186
Schistosoma mansoni cell adhesion molecule 0.0399 0.0686 0.0686
Echinococcus multilocularis tyrosine protein kinase shark 0.0393 0.0671 0.0671
Loa Loa (eye worm) hypothetical protein 0.0217 0.0206 0.0206
Echinococcus multilocularis protein jagged 1 0.0397 0.068 0.068
Brugia malayi Cadherin domain containing protein 0.0397 0.068 0.068
Brugia malayi Hr1 repeat family protein 0.0659 0.1373 0.1373
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0347 0.0548 0.0548
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.136 0.3225 0.3225
Brugia malayi Egg laying defective protein 4 0.0191 0.0138 0.0138
Echinococcus granulosus serine:threonine kinase SAD 1 0.0178 0.0101 0.0101
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.136 0.3225 1
Schistosoma mansoni serine/threonine protein kinase 0.0288 0.0393 0.0393
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.042 0.074 0.074
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Plasmodium falciparum cGMP-dependent protein kinase 0.0191 0.0138 0.0113
Loa Loa (eye worm) hypothetical protein 0.1115 0.2576 0.2576
Schistosoma mansoni protein kinase 0.0195 0.0148 0.0148
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0361 0.0586 0.0562
Leishmania major protein kinase, putative 0.0229 0.0237 0.0212
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0288 0.0393 0.0393
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0361 0.0586 0.2737
Echinococcus multilocularis expressed conserved protein 0.0191 0.0138 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0389 0.0659 0.1997
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0399 0.0686 0.3113
Loa Loa (eye worm) AGC/PKA protein kinase 0.0256 0.031 0.031
Schistosoma mansoni protein kinase 0.0501 0.0956 0.0956
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0337 0.0996
Brugia malayi Calcium binding EGF domain containing protein 0.0397 0.068 0.068
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0192 0.014 0.0115
Echinococcus multilocularis raf serine:threonine protein kinase 0.0169 0.0077 0.0077
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0361 0.0586 0.0562
Schistosoma mansoni cell adhesion molecule 0.042 0.074 0.074
Plasmodium falciparum ferrodoxin reductase-like protein 0.0361 0.0586 0.0562
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0208 0.0208
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0389 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0229 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0315 0.0463 0.0463
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0372 0.0615 0.0615
Schistosoma mansoni tyrosine kinase 0.0473 0.088 0.088
Schistosoma mansoni hypothetical protein 0.0181 0.0111 0.0111
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0267 0.0337 0.1539
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0799 0.1743 0.1743
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0361 0.0586 0.0586
Echinococcus granulosus Protein kinase C brain isozyme 0.0553 0.1092 0.1092
Loa Loa (eye worm) hypothetical protein 0.0217 0.0206 0.0206
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0292 0.0403 0.0403
Echinococcus multilocularis mitogen activated protein kinase 0.019 0.0134 0.0134
Trichomonas vaginalis glutamate synthase, putative 0.0361 0.0586 0.177
Brugia malayi C1-like domain containing protein 0.0493 0.0936 0.0936
Echinococcus granulosus neuroglian 0.042 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0423 0.0748 0.0748
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.136 0.3225 0.3208
Plasmodium vivax thioredoxin reductase, putative 0.3926 1 1
Loa Loa (eye worm) hypothetical protein 0.0361 0.0586 0.0586
Entamoeba histolytica PH domain containing protein kinase, putative 0.0372 0.0616 0.2882
Echinococcus granulosus serine/threonine protein kinase 0.0372 0.0616 0.0616
Loa Loa (eye worm) RhoGAP domain-containing protein 0.017 0.008 0.008
Onchocerca volvulus 0.0247 0.0283 0.1253
Schistosoma mansoni tyrosine kinase 0.0475 0.0886 0.0886
Echinococcus granulosus casein kinase I alpha 0.0247 0.0283 0.0283
Echinococcus granulosus basement membrane specific heparan sulfate 0.0217 0.0206 0.0206
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0134 0.0362
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0894 0.1992 0.1992
Echinococcus multilocularis tyrosine protein kinase 0.0349 0.0553 0.0553
Echinococcus multilocularis dual specificity 0.0277 0.0365 0.0365
Giardia lamblia Kinase, CAMK CAMKL 0.0195 0.0146 0.0051
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0253 0.0301 0.0301
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0349 0.0553 0.0553
Echinococcus granulosus dual specificity 0.0277 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.1046 0.2394 0.2394
Schistosoma mansoni protein kinase 0.0984 0.223 0.223
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0361 0.0586 0.0586
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0288 0.0393 0.0393
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.042 0.074 0.074
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0256 0.031 0.0194
Echinococcus multilocularis activin receptor type 0.0149 0.0025 0.0025
Giardia lamblia Kinase, CMGC CDK 0.027 0.0344 0.0691
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.019 0.0134 0.0109
Echinococcus granulosus titin 0.0181 0.0111 0.0111
Onchocerca volvulus Serine\/threonine kinase homolog 0.0372 0.0615 0.2787
Onchocerca volvulus Slit protein homolog 0.0447 0.0813 0.37
Plasmodium falciparum calcium-dependent protein kinase 1 0.0229 0.0237 0.0212
Echinococcus granulosus tyrosine protein kinase Fyn 0.0347 0.0548 0.0548
Echinococcus granulosus glutamate synthase 0.0361 0.0586 0.0586
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0686 0.0686
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0349 0.0553 0.0529
Echinococcus multilocularis glutamate synthase 0.0361 0.0586 0.0586
Echinococcus multilocularis serine:threonine protein kinase N2 0.0294 0.0408 0.0408
Schistosoma mansoni cell polarity protein 0.0397 0.068 0.068
Onchocerca volvulus 0.0418 0.0737 0.3352
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0337 0.0996
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0328 0.0499 0.0499
Echinococcus granulosus epidermal growth factor receptor 0.0549 0.1081 0.1081
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0178 0.0101 0.0076
Brugia malayi Protein kinase domain containing protein 0.0345 0.0543 0.0543
Trypanosoma brucei Casein kinase II 0.0227 0.0232 0.0208
Echinococcus granulosus titin 0.0181 0.0111 0.0111
Brugia malayi p70 ribosomal S6 kinase beta 0.0645 0.1337 0.1337
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0645 0.1337 0.1337
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0277 0.0365 0.034
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0372 0.0615 0.0615
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0182 0.0113 0.0113
Echinococcus granulosus activin receptor type 0.0149 0.0025 0.0025
Schistosoma mansoni protein kinase 0.0146 0.0018 0.0018
Echinococcus granulosus dual specificity 0.0315 0.0465 0.0465
Brugia malayi cyclin-dependent kinase 9 0.0172 0.0086 0.0086
Loa Loa (eye worm) casein kinase 0.0409 0.0711 0.0711
Schistosoma mansoni peroxidasin 0.0218 0.0208 0.0208
Plasmodium falciparum serine/threonine protein kinase KIN 0.0178 0.0101 0.0076
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0192 0.014 0.0587
Entamoeba histolytica SH2-protein kinase domain containing protein 0.015 0.0028 0.0048
Echinococcus granulosus protein kinase c iota type 0.0648 0.1343 0.1343
Loa Loa (eye worm) TK/INSR protein kinase 0.0681 0.1431 0.1431
Entamoeba histolytica hypothetical protein 0.0277 0.0365 0.1671
Schistosoma mansoni kinase 0.0172 0.0086 0.0086
Echinococcus granulosus hemicentin 1 0.0399 0.0686 0.0686
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0121 0.032
Schistosoma mansoni septate junction protein 0.0399 0.0686 0.0686
Echinococcus granulosus cGMP dependent protein kinase 0.0191 0.0138 0.0138
Echinococcus multilocularis hemicentin 1 0.0399 0.0686 0.0686
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0556 0.11 0.11
Schistosoma mansoni protein kinase 0.0984 0.223 0.223
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0292 0.0403 0.0379
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0361 0.0586 0.0562
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0361 0.0586 0.177
Toxoplasma gondii AGC kinase 0.0256 0.031 0.0285
Plasmodium falciparum calcium-dependent protein kinase 5 0.0229 0.0237 0.0212
Plasmodium falciparum thioredoxin reductase 0.136 0.3225 0.3208
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0455 0.0834 0.0834
Brugia malayi EGF-like domain containing protein 0.0397 0.068 0.068
Echinococcus granulosus calcium dependent protein kinase 0.0154 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0436 0.0783 0.0783
Echinococcus granulosus raf serine:threonine protein kinase 0.0169 0.0077 0.0077
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0277 0.0365 0.034
Echinococcus granulosus tyrosine kinase 0.0149 0.0025 0.0025
Giardia lamblia Kinase, AGC PKA 0.0256 0.031 0.0579
Plasmodium falciparum apical sushi protein 0.0732 0.1567 0.1545
Schistosoma mansoni tyrosine kinase 0.0549 0.1081 0.1081
Loa Loa (eye worm) hypothetical protein 0.0725 0.1546 0.1546
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0314 0.046 0.1379
Brugia malayi Homeodomain interacting protein kinase protein 1 0.046 0.0846 0.0846
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.136 0.3225 0.3225
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Schistosoma mansoni sulfide quinone reductase 0.0361 0.0586 0.0586
Entamoeba histolytica protein kinase, putative 0.0277 0.0365 0.1671
Brugia malayi glutamate synthase 0.0361 0.0586 0.0586
Toxoplasma gondii AGC kinase 0.0256 0.031 0.0285
Trypanosoma cruzi aurora B kinase, putative 0.0267 0.0337 0.0313
Brugia malayi Tyrosine-protein kinase abl-1 0.0213 0.0195 0.0195
Schistosoma mansoni serine/threonine protein kinase 0.1238 0.2901 0.2901
Brugia malayi Cadherin domain containing protein 0.0397 0.068 0.068
Echinococcus granulosus tyrosine protein kinase Lyn 0.0422 0.0746 0.0746
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0355 0.0571 0.0547
Echinococcus multilocularis titin 0.0277 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0933 0.2097 0.2097
Onchocerca volvulus 0.0737 0.1579 0.7244
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0365 0.0597 0.0597
Onchocerca volvulus 0.0324 0.0487 0.2194
Loa Loa (eye worm) TK protein kinase 0.0421 0.0745 0.0745
Echinococcus multilocularis rho associated protein kinase 0.0737 0.1579 0.1579
Echinococcus multilocularis neurogenic locus protein delta 0.0397 0.068 0.068
Schistosoma mansoni sulfide quinone reductase 0.0361 0.0586 0.0586
Brugia malayi serine/threonine protein kinase 6 0.0267 0.0337 0.0337
Onchocerca volvulus 0.0181 0.0111 0.0457
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0229 0.0237 0.0237
Echinococcus multilocularis protein tyrosine kinase 0.0654 0.1359 0.1359
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0101 0.0101
Schistosoma mansoni vesicular amine transporter 0.0716 0.1522 0.1522
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0181 0.0111 0.0111
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0361 0.0586 0.0586
Schistosoma mansoni cell adhesion molecule 0.042 0.074 0.074
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Echinococcus granulosus roundabout 2 0.1135 0.263 0.263
Echinococcus multilocularis NCK adaptor protein 0.0142 0.0006 0.0006
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0361 0.0586 0.0562
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.017 0.008 0.008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0181 0.0111 0.0111
Trichomonas vaginalis glutathione reductase, putative 0.136 0.3225 1
Entamoeba histolytica casein kinase, putative 0.0247 0.0283 0.1279
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1017 0.2318 0.2318
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0716 0.1522 0.1522
Loa Loa (eye worm) hypothetical protein 0.0418 0.0737 0.0737
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.019 0.0134 0.0109
Schistosoma mansoni protein kinase 0.0601 0.1218 0.1218
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0999 0.2271 0.2271
Brugia malayi Variant SH3 domain containing protein 0.017 0.008 0.008
Echinococcus granulosus titin 0.0181 0.0111 0.0111
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0702 0.1486 0.1486
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0166 0.0166
Mycobacterium ulcerans flavoprotein disulfide reductase 0.136 0.3225 1
Echinococcus granulosus Immunoglobulin 0.0217 0.0206 0.0206
Onchocerca volvulus 0.0732 0.1567 0.7186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Schistosoma mansoni serine/threonine protein kinase 0.0556 0.11 0.11
Trichomonas vaginalis AGC family protein kinase 0.0256 0.031 0.0909
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.042 0.074 0.074
Schistosoma mansoni cell adhesion molecule 0.0217 0.0206 0.0206
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0315 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.136 0.3225 0.3225
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.019 0.0134 0.0109
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Echinococcus multilocularis casein kinase I delta 0.0247 0.0283 0.0283
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0361 0.0586 0.177
Entamoeba histolytica serine/threonine protein kinase, putative 0.0613 0.1251 0.5942
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0211 0.0189 0.0189
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0599 0.1215 0.1215
Loa Loa (eye worm) hypothetical protein 0.0716 0.1524 0.1524
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.136 0.3225 0.3208
Loa Loa (eye worm) TK/ABL protein kinase 0.0149 0.0025 0.0025
Loa Loa (eye worm) TK protein kinase 0.0207 0.018 0.018
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0178 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.055 0.1086 0.1086
Entamoeba histolytica protein kinase, putative 0.015 0.0028 0.0048
Loa Loa (eye worm) CAMK protein kinase 0.0277 0.0364 0.0364
Schistosoma mansoni notch 0.0397 0.068 0.068
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0256 0.031 0.0285
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0831 0.1828 0.1828
Echinococcus granulosus mitogen activated protein kinase 11 0.0361 0.0585 0.0585
Brugia malayi Protein kinase domain containing protein 0.0663 0.1382 0.1382
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0256 0.031 0.031
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.136 0.3225 0.3208
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Entamoeba histolytica protein kinase, putative 0.0645 0.1337 0.6358
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Trichomonas vaginalis CAMK family protein kinase 0.0613 0.1251 0.3844
Echinococcus granulosus casein kinase I alpha 0.0247 0.0283 0.0283
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0799 0.1743 0.1743
Echinococcus granulosus serine:threonine protein kinase 0.0259 0.0316 0.0316
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0361 0.0586 0.2737
Leishmania major protein kinase, putative 0.0267 0.0337 0.0313
Trypanosoma cruzi hypothetical protein, conserved 0.0361 0.0586 0.0562
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.0389 0.1158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0232 0.0244 0.0244
Schistosoma mansoni laminin gamma-3 chain 0.0397 0.068 0.068
Trichomonas vaginalis AGC family protein kinase 0.0185 0.0121 0.032
Trichomonas vaginalis STE family protein kinase 0.0192 0.014 0.0379
Schistosoma mansoni c4b-binding protein beta chain 0.0732 0.1567 0.1567
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Entamoeba histolytica protein kinase domain containing protein 0.0292 0.0403 0.1857
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0182 0.0113 0.0113
Loa Loa (eye worm) TK/FAK protein kinase 0.0661 0.1377 0.1377
Trichomonas vaginalis CAMK family protein kinase 0.0613 0.1251 0.3844
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0229 0.0237 0.0237
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0361 0.0586 0.0473
Echinococcus multilocularis mitogen activated protein kinase 14 0.0361 0.0585 0.0585
Echinococcus multilocularis serine:threonine protein kinase N2 0.0365 0.0597 0.0597
Brugia malayi Protein kinase domain 0.0195 0.0148 0.0148
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0347 0.0548 0.0548
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.049 0.0926 0.0926
Brugia malayi EGF-like domain containing protein 0.0447 0.0813 0.0813
Echinococcus granulosus serine:threonine protein kinase MARK2 0.049 0.0926 0.0926
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0229 0.0237 0.0237
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0361 0.0586 0.0562
Brugia malayi ephrin receptor 1 precursor 0.0142 0.0008 0.0008
Brugia malayi map kinase activated protein kinase protein 2 0.0894 0.1992 0.1992
Brugia malayi GCC2 and GCC3 family protein 0.1129 0.2614 0.2614
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0025 0.0034
Schistosoma mansoni nephrin 0.0918 0.2056 0.2056
Echinococcus multilocularis protein jagged 2 0.0397 0.068 0.068
Echinococcus granulosus tyrosine protein kinase ABL1 0.0149 0.0025 0.0025
Echinococcus multilocularis death associated protein kinase 1 0.1009 0.2298 0.2298
Echinococcus multilocularis casein kinase ii subunit alpha 0.0227 0.0232 0.0232
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0238 0.0261 0.0261
Echinococcus granulosus serine threonine protein kinase nrc 0.0355 0.0571 0.0571
Schistosoma mansoni atypical protein kinase C 0.0662 0.138 0.138
Loa Loa (eye worm) TK/EPH protein kinase 0.0259 0.0315 0.0315
Onchocerca volvulus 0.0181 0.0111 0.0457
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0894 0.1992 0.1992
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0217 0.0206 0.0206
Brugia malayi protein-tyrosine kinase 0.0282 0.0378 0.0378
Loa Loa (eye worm) hypothetical protein 0.0202 0.0167 0.0167
Brugia malayi Leucine Rich Repeat family protein 0.0182 0.0113 0.0113
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0347 0.0548 0.0548
Onchocerca volvulus 0.0145 0.0015 0.0013
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0288 0.0393 0.0393
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0181 0.0111 0.0111
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.019 0.0134 0.0109
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0361 0.0585 0.0562
Echinococcus granulosus down syndrome cell adhesion 0.0181 0.0111 0.0111
Plasmodium vivax protein kinase Crk2 0.027 0.0344 0.0229
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0229 0.0237 0.0212
Echinococcus multilocularis netrin receptor unc 5 0.0283 0.0379 0.0379
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0504 0.0963 0.0963
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0361 0.0586 0.177
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0355 0.0571 0.0458
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Plasmodium falciparum thioredoxin reductase 0.3926 1 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.042 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Echinococcus multilocularis roundabout 2 0.042 0.074 0.074
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0181 0.0111 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.0365 0.0365
Echinococcus granulosus mitogen activated protein kinase 14 0.0361 0.0585 0.0585
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0465 0.1393
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.017 0.0475
Schistosoma mansoni hypothetical protein 0.0217 0.0206 0.0206
Brugia malayi hypothetical protein 0.0253 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0399 0.0686 0.0686
Entamoeba histolytica protein kinase, putative 0.0229 0.0237 0.1054
Echinococcus granulosus rho-associated protein kinase 1 0.0737 0.1579 0.1579
Echinococcus multilocularis cyclin dependent kinase 19 0.1238 0.2901 0.2901
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0556 0.11 0.11
Toxoplasma gondii casein kinase I 0.0247 0.0283 0.0259
Loa Loa (eye worm) AGC/AKT protein kinase 0.0663 0.1382 0.1382
Trichomonas vaginalis AGC family protein kinase 0.0382 0.0642 0.1944
Loa Loa (eye worm) gastrulation defective protein 1 0.1163 0.2702 0.2702
Plasmodium vivax casein kinase 1, putative 0.0247 0.0283 0.0167
Brugia malayi Temporarily assigned gene name protein 59 0.0292 0.0404 0.0404
Echinococcus granulosus neurogenic locus notch protein 0.0397 0.068 0.068
Brugia malayi Calcium binding EGF domain containing protein 0.0397 0.068 0.068
Trichomonas vaginalis AGC family protein kinase 0.0406 0.0704 0.2139
Trichomonas vaginalis CAMK family protein kinase 0.0287 0.0389 0.1158
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0253 0.0301 0.0301
Echinococcus granulosus titin 0.0277 0.0364 0.0364
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0344 0.1017
Echinococcus granulosus casein kinase I gamma 0.0484 0.0909 0.0909
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0493 0.0936 0.0936
Loa Loa (eye worm) hypothetical protein 0.0732 0.1567 0.1567
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0361 0.0586 0.0586
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0361 0.0586 0.0562
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0189 0.013 0.0106
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Plasmodium falciparum calcium-dependent protein kinase 2 0.0229 0.0237 0.0212
Trypanosoma brucei cdc2-related kinase 3 0.027 0.0344 0.032
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.027 0.0344 0.0344
Echinococcus granulosus ephrin type A receptor 4 A 0.0219 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0185 0.012 0.012
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0253 0.0301 0.0277
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0549 0.1081 0.1081
Echinococcus multilocularis expressed protein 0.0189 0.013 0.013
Onchocerca volvulus 0.0361 0.0586 0.2651
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0716 0.1522 0.1522
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0217 0.0206 0.0206
Schistosoma mansoni protein kinase 0.0227 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0526 0.102 0.102
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0556 0.11 0.11
Echinococcus multilocularis serine:threonine protein kinase 0.0259 0.0316 0.0316
Echinococcus multilocularis ephrin type A receptor 4 A 0.0219 0.021 0.021
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0189 0.013 0.0106
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0195 0.0148 0.0148
Loa Loa (eye worm) LAD-2 short isoform 0.0217 0.0206 0.0206
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0613 0.1251 0.1251
Leishmania major protein kinase A catalytic subunit 0.0256 0.031 0.0285
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0361 0.0586 0.0586
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0185 0.0121 0.0121
Brugia malayi cell division control protein 2 homolog 0.027 0.0344 0.0344
Entamoeba histolytica protein kinase, putative 0.0292 0.0403 0.1857
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0261 0.0322 0.0322
Schistosoma mansoni tyrosine kinase 0.0787 0.1711 0.1711
Echinococcus multilocularis casein kinase i 0.0247 0.0283 0.0283
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0166 0.0166
Leishmania major protein kinase, putative 0.0349 0.0553 0.0529
Loa Loa (eye worm) AGC/PKA protein kinase 0.0256 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0217 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0217 0.0206 0.0206
Onchocerca volvulus 0.0149 0.0025 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0361 0.0586 0.0586
Echinococcus multilocularis protein kinase shaggy 0.0292 0.0403 0.0403
Schistosoma mansoni protein kinase 0.0247 0.0283 0.0283
Schistosoma mansoni notch 0.0397 0.068 0.068
Echinococcus multilocularis 0.0273 0.0354 0.0354
Giardia lamblia Kinase, CDC7 0.0204 0.017 0.0129
Schistosoma mansoni growth factor receptor-bound protein 0.0142 0.0006 0.0006
Toxoplasma gondii EGF family domain-containing protein 0.0397 0.068 0.0656
Echinococcus granulosus calcium activated potassium channel 0.0306 0.044 0.044
Schistosoma mansoni protein kinase C mu 0.0493 0.0936 0.0936
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0277 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0447 0.0813 0.0813
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0686 0.0686
Echinococcus granulosus mitogen activated protein kinase 3 0.019 0.0134 0.0134
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0315 0.0465 0.0441
Schistosoma mansoni serine/threonine kinase 0.0365 0.0597 0.0597
Loa Loa (eye worm) AUR protein kinase 0.0267 0.0337 0.0337
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0361 0.0586 0.0562
Echinococcus granulosus C type lectin domian containing protein 0.0732 0.1567 0.1567
Entamoeba histolytica protein kinase, putative 0.0207 0.018 0.078
Schistosoma mansoni protein kinase 0.0347 0.055 0.055
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0134 0.0362
Echinococcus multilocularis 0.0347 0.055 0.055
Loa Loa (eye worm) TK/EGFR protein kinase 0.0787 0.1711 0.1711
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0361 0.0586 0.177
Brugia malayi Prion-like- 0.0181 0.0111 0.0111
Echinococcus granulosus roundabout 2 0.042 0.074 0.074
Brugia malayi kettin 0.0181 0.0111 0.0111
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Trypanosoma brucei SNF1-related protein kinases, putative 0.0178 0.0101 0.0076
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0799 0.1743 0.1743
Loa Loa (eye worm) programmed cell death 8 0.0361 0.0586 0.0586
Loa Loa (eye worm) hypothetical protein 0.0716 0.1522 0.1522
Loa Loa (eye worm) disorganized muscle protein 1 0.0181 0.0111 0.0111
Echinococcus granulosus insulin growth factor binding 0.0181 0.0111 0.0111
Trypanosoma brucei hypothetical protein, conserved 0.0361 0.0586 0.0562
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0519 0.1002 0.1002
Brugia malayi SRC-1 0.0347 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0399 0.0686 0.0686
Schistosoma mansoni nephrin related 0.0217 0.0206 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.044 0.044
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.136 0.3225 0.3208
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0315 0.0465 0.0441
Trypanosoma cruzi cdc2-related kinase 1 0.027 0.0344 0.032
Echinococcus multilocularis serine threonine protein kinase 0.0458 0.0842 0.0842
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0344 0.0344
Brugia malayi Immunoglobulin domain containing protein 0.0217 0.0206 0.0206
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0347 0.0548 0.0548
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.031 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0365 0.0597 0.0597
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0178 0.0101 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.046 0.0846 0.399
Echinococcus multilocularis cyclin dependent kinase 9 0.0172 0.0086 0.0086
Echinococcus multilocularis PAK box P21 Rho binding 0.0146 0.0018 0.0018
Onchocerca volvulus Serine\/threonine kinase homolog 0.0613 0.1251 0.5725
Schistosoma mansoni tyrosine kinase 0.0393 0.0671 0.0671
Echinococcus granulosus tyrosine protein kinase Fyn 0.0347 0.0548 0.0548
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0181 0.0111 0.0111
Brugia malayi Protein kinase domain containing protein 0.2135 0.5271 0.5271
Echinococcus granulosus homeodomain interacting protein kinase 3 0.046 0.0846 0.0846
Trichomonas vaginalis STE family protein kinase 0.0309 0.0448 0.134
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0831 0.1828 0.1828
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0166 0.0166
Onchocerca volvulus Peroxidasin homolog 0.0181 0.0111 0.0457
Giardia lamblia Kinase, CMGC MAPK 0.019 0.0134 0.0012
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0238 0.0261 0.0261
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0191 0.0138 0.0138
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0309 0.0448 0.0424
Loa Loa (eye worm) hypothetical protein 0.0253 0.0301 0.0301
Trypanosoma cruzi cdc2-related kinase 3 0.027 0.0344 0.032
Echinococcus granulosus protein jagged 2 0.0397 0.068 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Loa Loa (eye worm) hypothetical protein 0.0423 0.0748 0.0748
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0361 0.0586 0.0586
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0292 0.0403 0.0403
Giardia lamblia Kinase, CMGC DYRK 0.0315 0.0465 0.1081
Trichomonas vaginalis CAMK family protein kinase 0.0492 0.0932 0.2849
Echinococcus multilocularis titin 0.0181 0.0111 0.0111
Brugia malayi P38 map kinase family protein 2 0.0361 0.0585 0.0585
Giardia lamblia Kinase, PLK 0.0613 0.1251 0.362
Giardia lamblia Kinase, CAMK CAMKL 0.0195 0.0146 0.0051
Trypanosoma cruzi NADH dehydrogenase, putative 0.0361 0.0586 0.0562
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0349 0.0553 0.0529
Entamoeba histolytica protein kinase, putative 0.0189 0.013 0.0542
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0337 0.0996
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0361 0.0586 0.2737
Echinococcus granulosus expressed protein 0.0189 0.013 0.013
Brugia malayi Protein kinase domain containing protein 0.0277 0.0365 0.0365
Onchocerca volvulus 0.0397 0.068 0.3085
Echinococcus granulosus casein kinase I delta 0.0247 0.0283 0.0283
Echinococcus multilocularis serine:threonine protein kinase 38 0.0365 0.0597 0.0597
Echinococcus multilocularis serine:threonine protein kinase 0.0259 0.0316 0.0316
Echinococcus granulosus protein tyrosine kinase 0.0654 0.1359 0.1359
Onchocerca volvulus 0.0172 0.0085 0.0336
Onchocerca volvulus 0.0204 0.017 0.073
Brugia malayi EGF-like domain containing protein 0.0397 0.068 0.068
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0261 0.0322 0.0322
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0613 0.1251 0.1251
Trypanosoma cruzi casein kinase, putative 0.0247 0.0283 0.0259
Echinococcus granulosus cGMP dependent protein kinase 1 0.0191 0.0138 0.0138
Schistosoma mansoni basigin related 0.0217 0.0206 0.0206
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0256 0.031 0.0285
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0355 0.0571 0.0571
Onchocerca volvulus 0.0181 0.0111 0.0457
Schistosoma mansoni myosin-binding protein-related 0.0202 0.0166 0.0166
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0361 0.0586 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0337 0.0337
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0347 0.0548 0.0548
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.017 0.017
Trypanosoma brucei protein kinase, putative 0.0207 0.0179 0.0154
Trichomonas vaginalis CK1 family protein kinase 0.0247 0.0283 0.0827
Trichomonas vaginalis CK1 family protein kinase 0.0247 0.0283 0.0827
Schistosoma mansoni hypothetical protein 0.0217 0.0206 0.0206
Onchocerca volvulus 0.0397 0.068 0.3085
Onchocerca volvulus 0.0181 0.0111 0.0457
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Brugia malayi Furin-like cysteine rich region family protein 0.0787 0.1711 0.1711
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0799 0.1743 0.1743
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0195 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Trypanosoma cruzi cdc2-related kinase 3 0.027 0.0344 0.032
Brugia malayi putative serine/threonine kinase SADA gamma 0.0178 0.0101 0.0101
Echinococcus multilocularis epidermal growth factor receptor 0.0787 0.1711 0.1711
Brugia malayi probable protein kinase 0.0601 0.1218 0.1218
Brugia malayi Immunoglobulin I-set domain containing protein 0.0283 0.0379 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0121 0.0121
Schistosoma mansoni septate junction protein 0.0217 0.0206 0.0206
Plasmodium falciparum casein kinase 1 0.0247 0.0283 0.0259
Schistosoma mansoni cell adhesion molecule 0.0202 0.0166 0.0166
Echinococcus granulosus casein kinase i 0.0247 0.0283 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.1092 0.1092
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Giardia lamblia Aurora kinase 0.0267 0.0337 0.0669
Loa Loa (eye worm) protein kinase domain-containing protein 0.0484 0.0909 0.0909
Echinococcus granulosus c4b binding protein beta chain 0.0732 0.1567 0.1567
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0702 0.1486 0.1486
Brugia malayi protein unc-22 0.0277 0.0364 0.0364
Schistosoma mansoni hypothetical protein 0.0181 0.0111 0.0111
Echinococcus granulosus tyrosine protein kinase Fyn 0.0347 0.0548 0.0548
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0909 0.0909
Brugia malayi STE20-like kinase MST 0.0582 0.117 0.117
Brugia malayi basement membrane proteoglycan 0.0217 0.0206 0.0206
Brugia malayi hypothetical protein 0.0149 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0315 0.0463 0.0463
Brugia malayi Protein kinase domain containing protein 0.0389 0.0659 0.0659
Echinococcus multilocularis neurogenic locus notch protein 0.0397 0.068 0.068
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0526 0.1022 0.1022
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0361 0.0586 0.1472
Loa Loa (eye worm) TK protein kinase 0.0282 0.0378 0.0378
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0181 0.0111 0.0111
Echinococcus granulosus neuroglian 0.0897 0.2002 0.2002
Plasmodium falciparum glutathione reductase 0.3926 1 1
Onchocerca volvulus 0.0253 0.0301 0.1334
Trichomonas vaginalis CAMK family protein kinase 0.0613 0.1251 0.3844
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0288 0.0393 0.0393
Brugia malayi casein kinase I 0.0247 0.0283 0.0283
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.1092 0.1092
Onchocerca volvulus 0.0732 0.1567 0.7186
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0189 0.013 0.0106
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0397 0.068 0.068
Schistosoma mansoni vam6/vps39 related 0.0253 0.0301 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0101 0.0101
Onchocerca volvulus 0.0292 0.0403 0.1807
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0229 0.0237 0.0237
Echinococcus multilocularis C type lectin domian containing protein 0.0732 0.1567 0.1567
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3926 1 1
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis mitogen activated protein kinase 3 0.019 0.0134 0.0134
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0399 0.0686 0.0686
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0172 0.0085 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0613 0.1251 0.3844
Echinococcus multilocularis cyclin dependent kinase 9 0.0189 0.0131 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.042 0.074 0.074
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0465 0.1393
Brugia malayi Cyclin, N-terminal domain containing protein 0.0918 0.2058 0.2058
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0237 0.0237
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.042 0.074 0.074
Loa Loa (eye worm) AGC/PKG protein kinase 0.0191 0.0138 0.0138
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0455 0.0834 0.0834
Echinococcus granulosus notch 0.0397 0.068 0.068
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Loa Loa (eye worm) notch protein 0.0397 0.068 0.068
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0361 0.0586 0.0562
Echinococcus multilocularis calcium dependent protein kinase 0.0154 0.0038 0.0038
Brugia malayi EGF-like domain containing protein 0.0397 0.068 0.068
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0166 0.0166
Echinococcus multilocularis serine:threonine protein kinase N2 0.0659 0.1373 0.1373
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0372 0.0616 0.0592
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0149 0.0025 0.0025
Brugia malayi Doublecortin family protein 0.0342 0.0536 0.0536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0686 0.0686
Schistosoma mansoni nephrin related 0.0181 0.0111 0.0111
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.049 0.0926 0.0926
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0256 0.031 0.031
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0181 0.0111 0.0111
Brugia malayi Protein kinase domain containing protein 0.0259 0.0316 0.0316
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0361 0.0586 0.0586
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0553 0.1092 0.1092
Schistosoma mansoni glutamate synthase 0.0361 0.0586 0.0586
Plasmodium vivax apical sushi protein, putative 0.0732 0.1567 0.1466
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Onchocerca volvulus Putative cubilin 0.0397 0.068 0.3085
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0178 0.0101 0.0101
Brugia malayi Protein kinase domain containing protein 0.0149 0.0025 0.0025
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0999 0.2271 0.2271
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0347 0.0548 0.0548
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.019 0.0134 0.0134
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0496 0.0943 0.0943
Brugia malayi Protein kinase domain containing protein 0.0349 0.0553 0.0553
Onchocerca volvulus 0.0732 0.1567 0.7186
Trypanosoma cruzi casein kinase, putative 0.0247 0.0283 0.0259
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0166 0.0166
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Echinococcus multilocularis hemicentin 1 0.0399 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0202 0.0166 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.0364 0.0364
Echinococcus multilocularis contactin neuroglian septate junction protein 0.042 0.074 0.074
Plasmodium falciparum calcium-dependent protein kinase 4 0.0229 0.0237 0.0212
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0365 0.0597 0.0597
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0184 0.0118 0.0093
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0533 0.104 0.104
Echinococcus multilocularis mitogen activated protein kinase 11 0.0361 0.0585 0.0585
Toxoplasma gondii AGC kinase 0.0645 0.1337 0.1315
Echinococcus multilocularis neurogenic locus notch protein 4 0.0397 0.068 0.068
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.136 0.3225 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0361 0.0586 0.177
Plasmodium falciparum glutathione reductase 0.136 0.3225 0.3208
Brugia malayi Cyclin C 0.1836 0.4481 0.4481
Onchocerca volvulus 0.0732 0.1567 0.7186
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.017 0.0475
Echinococcus multilocularis dual specificity 0.0315 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Echinococcus granulosus protein jagged 1 0.0397 0.068 0.068
Entamoeba histolytica protein kinase domain containing protein 0.0172 0.0086 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0077 0.0077
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0253 0.0301 0.0277
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0185 0.0121 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0599 0.1215 0.1215
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.136 0.3225 0.2803
Brugia malayi intracellular kinase 0.0292 0.0403 0.0403
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0347 0.0548 0.0548
Trypanosoma brucei NADH dehydrogenase 0.0361 0.0586 0.0562
Schistosoma mansoni cell adhesion molecule 0.0181 0.0111 0.0111
Brugia malayi Prion-like- 0.0181 0.0111 0.0111
Brugia malayi Protein kinase domain containing protein 0.0349 0.0553 0.0553
Loa Loa (eye worm) TK/ALK protein kinase 0.0345 0.0543 0.0543
Trichomonas vaginalis AGC family protein kinase 0.0309 0.0448 0.134
Brugia malayi Stress-activated protein kinase jnk-1 0.0599 0.1215 0.1215
Brugia malayi Immunoglobulin I-set domain containing protein 0.0593 0.12 0.12
Entamoeba histolytica protein kinase, putative 0.0365 0.0597 0.2789
Loa Loa (eye worm) thyroid receptor interactor 0.0232 0.0244 0.0244
Giardia lamblia Glutamate synthase 0.0361 0.0586 0.1472
Trypanosoma brucei casein kinase I, isoform 2 0.0247 0.0283 0.0259
Brugia malayi Protein kinase domain containing protein 0.0149 0.0025 0.0025
Onchocerca volvulus 0.0732 0.1567 0.7186
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0267 0.0337 0.1539
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0347 0.0548 0.0548
Plasmodium vivax ferrodoxin reductase, putative 0.0361 0.0586 0.0473
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Schistosoma mansoni protein kinase 0.0437 0.0787 0.0787
Onchocerca volvulus 0.0436 0.0783 0.3562
Schistosoma mansoni tyrosine kinase 0.0412 0.072 0.072
Schistosoma mansoni notch 0.0397 0.068 0.068
Schistosoma mansoni hypothetical protein 0.0231 0.0242 0.0242
Onchocerca volvulus 0.0277 0.0364 0.1626
Entamoeba histolytica protein kinase, putative 0.0163 0.0063 0.0219
Echinococcus multilocularis neural cadherin 0.0397 0.068 0.068
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Loa Loa (eye worm) TK protein kinase 0.0593 0.12 0.12
Toxoplasma gondii aurora kinase 0.0267 0.0337 0.0313
Brugia malayi Heparan sulfate 0.0217 0.0206 0.0206
Brugia malayi Prion-like- 0.0399 0.0686 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0138 0.0138
Schistosoma mansoni basigin related 0.0217 0.0206 0.0206
Brugia malayi Protein kinase domain containing protein 0.0725 0.1546 0.1546
Loa Loa (eye worm) hypothetical protein 0.0275 0.0358 0.0358
Schistosoma mansoni hypothetical protein 0.0217 0.0206 0.0206
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0256 0.031 0.0285
Toxoplasma gondii selenide, water dikinase 0.0361 0.0586 0.0562
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis c src tyrosine kinase 0.0213 0.0195 0.0195
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0344 0.0344
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0361 0.0586 0.0562
Leishmania major trypanothione reductase 0.3926 1 1
Loa Loa (eye worm) Notch2 0.0397 0.068 0.068
Echinococcus granulosus neurogenic locus protein delta 0.0397 0.068 0.068
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0229 0.0237 0.0237
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0255 0.0306 0.0306
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0716 0.1522 0.1522
Schistosoma mansoni serine/threonine protein kinase 0.0659 0.1373 0.1373
Schistosoma mansoni nephrin 0.042 0.074 0.074
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Loa Loa (eye worm) hypothetical protein 0.1129 0.2614 0.2614
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0217 0.0206 0.0206
Plasmodium falciparum serine/threonine protein kinase, putative 0.0267 0.0337 0.0313
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0361 0.0586 0.0473
Brugia malayi Sushi domain 0.0732 0.1567 0.1567
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Schistosoma mansoni protein kinase 0.0267 0.0337 0.0337
Echinococcus multilocularis thioredoxin glutathione reductase 0.3926 1 1
Brugia malayi Protein kinase domain containing protein 0.0149 0.0025 0.0025
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0229 0.0237 0.012
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0172 0.0086 0.0086
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0501 0.0956 0.0956
Leishmania major dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0277 0.0364 0.0364
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Echinococcus granulosus cyclin dependent kinase 9 0.0189 0.0131 0.0131
Echinococcus granulosus casein kinase I alpha 0.0247 0.0283 0.0283
Echinococcus granulosus mitogen activated protein kinase 0.019 0.0134 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0166 0.046
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0195 0.0146 0.0029
Trypanosoma brucei aurora B kinase 0.0267 0.0337 0.0313
Loa Loa (eye worm) hypothetical protein 0.068 0.1427 0.1427
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.017 0.008 0.008
Toxoplasma gondii thioredoxin reductase 0.3926 1 1
Trypanosoma cruzi casein kinase II, putative 0.0227 0.0232 0.0208
Echinococcus granulosus tyrosine protein kinase Src42A 0.0347 0.0548 0.0548
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0918 0.2058 0.2058
Echinococcus granulosus CDC7 cell division cycle 7 0.0204 0.017 0.017
Brugia malayi Immunoglobulin domain containing protein 0.0217 0.0206 0.0206
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.031 0.031
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0185 0.0121 0.0121
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0202 0.0166 0.0166
Echinococcus multilocularis fat cadherin tumor suppressor 0.0397 0.068 0.068
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0292 0.0403 0.0403
Echinococcus multilocularis transfer RNA-Phe 0.0202 0.0166 0.0166
Brugia malayi protein kinase C II. 0.0463 0.0855 0.0855
Onchocerca volvulus 0.0149 0.0025 0.0057
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0504 0.0963 0.0963
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0399 0.0686 0.0686
Echinococcus granulosus c src tyrosine kinase 0.0213 0.0195 0.0195
Echinococcus granulosus Vam6:Vps39 protein 0.0253 0.0301 0.0301
Loa Loa (eye worm) glutathione reductase 0.3926 1 1
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0217 0.0206 0.0206
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0582 0.117 0.117
Entamoeba histolytica cyclin C, putative 0.0932 0.2092 1
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Schistosoma mansoni hypothetical protein 0.0217 0.0206 0.0206
Loa Loa (eye worm) SRC-1 0.0347 0.0548 0.0548
Trichomonas vaginalis CMGC family protein kinase 0.0292 0.0403 0.1201
Echinococcus granulosus serine:threonine protein kinase N2 0.0294 0.0408 0.0408
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0322 0.0947
Brugia malayi Protein kinase domain containing protein 0.0149 0.0025 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Trypanosoma cruzi trypanothione reductase, putative 0.3926 1 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0277 0.0364 0.0364
Echinococcus multilocularis c4b binding protein beta chain 0.0732 0.1567 0.1567
Schistosoma mansoni serine/threonine protein kinase 0.0533 0.104 0.104
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Schistosoma mansoni cell adhesion molecule 0.0217 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0736 0.1577 0.1577
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.019 0.0134 0.0109
Echinococcus multilocularis Immunoglobulin subtype 0.0217 0.0206 0.0206
Echinococcus multilocularis hypothetical protein 0.0231 0.0242 0.0242
Brugia malayi Immunoglobulin I-set domain containing protein 0.0399 0.0686 0.0686
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0355 0.0571 0.0571
Schistosoma mansoni titin 0.0181 0.0111 0.0111
Brugia malayi serine/threonine-protein kinase 6 0.0267 0.0337 0.0337
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0101 0.0101
Echinococcus granulosus contactin 0.042 0.074 0.074
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0316 0.0929
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Schistosoma mansoni netrin receptor unc5 0.0217 0.0206 0.0206
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0361 0.0585 0.0562
Brugia malayi serine/threonine-protein kinase PAK 7 0.0526 0.1022 0.1022
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0277 0.0365 0.034
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0282 0.0378 0.0378
Echinococcus multilocularis serine:threonine protein kinase 3 0.0582 0.117 0.117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0736 0.1577 0.1577
Schistosoma mansoni glutamate synthase 0.0361 0.0586 0.0586
Brugia malayi EGF-like domain containing protein 0.0397 0.068 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Brugia malayi EGF-like domain containing protein 0.0397 0.068 0.068
Schistosoma mansoni kinase 0.0655 0.1361 0.1361
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.046 0.0846 0.0846
Entamoeba histolytica protein kinase, putative 0.0195 0.0148 0.0626
Loa Loa (eye worm) TK/ROR protein kinase 0.0255 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.042 0.074 0.074
Schistosoma mansoni disulfide oxidoreductase 0.0361 0.0586 0.0586
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.136 0.3225 0.2803
Entamoeba histolytica protein kinase domain containing protein 0.0277 0.0365 0.1671
Echinococcus multilocularis twitchin 0.0256 0.031 0.031
Giardia lamblia Kinase, NEK 0.0309 0.0448 0.1026
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0267 0.0337 0.1539
Loa Loa (eye worm) hypothetical protein 0.0178 0.0101 0.0101
Giardia lamblia High cysteine protein 0.0397 0.068 0.1775
Schistosoma mansoni serine/threonine kinase 0.0509 0.0976 0.0976
Trichomonas vaginalis mercuric reductase, putative 0.136 0.3225 1
Brugia malayi Protein kinase domain containing protein 0.0831 0.1828 0.1828
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.019 0.0134 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.031 0.031
Trypanosoma cruzi trypanothione reductase, putative 0.136 0.3225 0.3208
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0347 0.0548 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Echinococcus granulosus serine:threonine protein kinase 3 0.0582 0.117 0.117
Echinococcus multilocularis Immunoglobulin 0.0716 0.1522 0.1522
Loa Loa (eye worm) hypothetical protein 0.0736 0.1577 0.1577
Echinococcus granulosus growth factor receptor bound protein 2 0.0142 0.0006 0.0006
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0361 0.0586 0.0586
Trichomonas vaginalis CMGC family protein kinase 0.0227 0.0232 0.0668
Echinococcus multilocularis titin 0.0181 0.0111 0.0111
Schistosoma mansoni tyrosine kinase 0.0347 0.0548 0.0548
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0613 0.1251 0.1229
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Echinococcus multilocularis calcium activated potassium channel 0.0306 0.044 0.044
Toxoplasma gondii rhoptry neck protein RON1 0.0732 0.1567 0.1545
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0371 0.0613 0.0613
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0184 0.0118 0.0093
Echinococcus multilocularis casein kinase I gamma 0.0484 0.0909 0.0909
Echinococcus granulosus dual specificity protein kinase clk2 0.0349 0.0553 0.0553
Schistosoma mansoni septate junction protein 0.0399 0.0686 0.0686
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.136 0.3225 0.3144
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0984 0.223 0.223
Giardia lamblia Kinase, AGC PKA 0.0355 0.0571 0.1422
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Loa Loa (eye worm) hypothetical protein 0.0253 0.0301 0.0301
Plasmodium vivax glutathione reductase, putative 0.3926 1 1
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Echinococcus granulosus delta-like protein 1 0.0397 0.068 0.068
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0455 0.0835 0.0835
Trypanosoma cruzi Protein kinase B 0.0372 0.0616 0.0592
Plasmodium falciparum NIMA related kinase 1 0.0309 0.0448 0.0424
Echinococcus multilocularis 0.0181 0.0111 0.0111
Echinococcus granulosus cyclin 0.0918 0.2058 0.2058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Leishmania major casein kinase II, putative 0.0227 0.0232 0.0208
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0361 0.0586 0.0586
Echinococcus granulosus protein kinase shaggy 0.0292 0.0403 0.0403
Brugia malayi Immunoglobulin I-set domain containing protein 0.0202 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0736 0.1577 0.1577
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Loa Loa (eye worm) AGC/NDR protein kinase 0.0365 0.0597 0.0597
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Entamoeba histolytica PH domain containing protein kinase, putative 0.0274 0.0355 0.1624
Schistosoma mansoni titin 0.0202 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0399 0.0686 0.0686
Echinococcus granulosus fibroblast growth factor receptor 4 0.0412 0.072 0.072
Loa Loa (eye worm) hypothetical protein 0.0195 0.0146 0.0146
Plasmodium falciparum casein kinase 2, alpha subunit 0.0227 0.0232 0.0208
Echinococcus granulosus hypothetical protein 0.0273 0.0354 0.0354
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0412 0.072 0.072
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0256 0.031 0.0285
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Echinococcus multilocularis roundabout 2 0.042 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Trypanosoma cruzi cdc2-related kinase 1 0.027 0.0344 0.032
Plasmodium vivax calcium-dependent protein kinase, putative 0.0229 0.0237 0.012
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1121 0.2592 0.2592
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0361 0.0586 0.0562
Echinococcus multilocularis tyrosine protein kinase Srms 0.0282 0.0378 0.0378
Schistosoma mansoni serine/threonine-protein kinase 0.0372 0.0616 0.0616
Loa Loa (eye worm) hypothetical protein 0.0231 0.0242 0.0242
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0599 0.1215 0.1215
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0178 0.0101 0.0076
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0504 0.0963 0.0963
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0227 0.0232 0.0232
Schistosoma mansoni hypothetical protein 0.0181 0.0111 0.0111
Echinococcus granulosus casein kinase I delta 0.0247 0.0283 0.0283
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0283 0.0379 0.0355
Entamoeba histolytica PH domain containing protein kinase, putative 0.0372 0.0616 0.2882
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0894 0.1992 0.1992
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0349 0.0553 0.0529
Echinococcus granulosus slit 2 protein 0.0447 0.0813 0.0813
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0437 0.0787 0.0787
Echinococcus granulosus cyclin dependent kinase 0.027 0.0344 0.0344
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0292 0.0403 0.0379
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0195 0.0148 0.0148
Echinococcus multilocularis neuroglian 0.0897 0.2002 0.2002
Entamoeba histolytica protein kinase domain containing protein 0.0315 0.0465 0.2154
Echinococcus granulosus low density lipoprotein receptor ldl 0.0217 0.0206 0.0206
Leishmania major protein kinase A catalytic subunit isoform 2 0.0256 0.031 0.0285
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0501 0.0956 0.0956
Giardia lamblia Kinase, CMGC CDK 0.027 0.0344 0.0691
Onchocerca volvulus 0.0202 0.0166 0.0709
Echinococcus granulosus tyrosine protein kinase HCK 0.0207 0.018 0.018
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0755 0.1626 0.1626
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0181 0.0111 0.0111
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0253 0.0301 0.0301
Entamoeba histolytica casein kinase, putative 0.0227 0.0232 0.1033
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0229 0.0237 0.0237
Plasmodium falciparum protein serine/threonine kinase-1 0.0349 0.0553 0.0529
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0361 0.0586 0.0562
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0329 0.05 0.05
Brugia malayi Calcium binding EGF domain containing protein 0.0397 0.068 0.068
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Plasmodium falciparum serine/threonine protein kinase 0.0189 0.013 0.0106
Entamoeba histolytica p21-activated kinase 0.0212 0.0193 0.0844
Onchocerca volvulus 0.0181 0.0111 0.0457
Entamoeba histolytica cell division protein kinase 2, putative 0.027 0.0344 0.1572
Trypanosoma cruzi hypothetical protein, conserved 0.0361 0.0586 0.0562
Giardia lamblia Kinase, STE STE20 0.0195 0.0148 0.0056
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0463 0.0855 0.0855
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0247 0.0283 0.0283
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.136 0.3225 1
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0256 0.031 0.0285
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0399 0.0686 0.0686
Trichomonas vaginalis AGC family protein kinase 0.0267 0.0337 0.0996
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0399 0.0686 0.0686
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0292 0.0403 0.0379
Echinococcus granulosus tyrosine protein kinase Blk 0.0282 0.0378 0.0378
Brugia malayi Fibronectin type III domain containing protein 0.0736 0.1577 0.1577
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0256 0.031 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0578 0.1159 0.1159
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.027 0.0344 0.032
Echinococcus granulosus cyclin dependent kinase 5 0.027 0.0344 0.0344
Entamoeba histolytica protein kinase, putative 0.0185 0.0121 0.0495
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0361 0.0586 0.0586
Echinococcus multilocularis tyrosine protein kinase Abl 0.0213 0.0195 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Echinococcus granulosus c-Jun N-terminal kinases 0.0599 0.1215 0.1215
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.0615 0.0615
Loa Loa (eye worm) cyclin domain-containing protein 0.0918 0.2058 0.2058
Echinococcus multilocularis lachesin 0.0399 0.0686 0.0686
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.136 0.3225 0.3225
Schistosoma mansoni slit 0.0397 0.0681 0.0681
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0349 0.0553 0.0529
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0361 0.0586 0.177
Echinococcus multilocularis neurogenic locus protein delta 0.0397 0.068 0.068
Echinococcus granulosus titin 0.0277 0.0364 0.0364
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0309 0.0448 0.0334
Schistosoma mansoni serine/threonine-protein kinase 0.0372 0.0616 0.0616
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0329 0.05 0.05
Onchocerca volvulus Tyrosine kinase homolog 0.0963 0.2175 1
Schistosoma mansoni netrin receptor unc5 0.0283 0.0379 0.0379
Leishmania major casein kinase, putative 0.0247 0.0283 0.0259
Echinococcus granulosus tyrosine protein kinase Src64B 0.0347 0.0548 0.0548
Treponema pallidum NADH oxidase 0.136 0.3225 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Plasmodium vivax serine/threonine protein kinase, putative 0.0189 0.013 0.0013
Echinococcus multilocularis casein kinase I alpha 0.0247 0.0283 0.0283
Brugia malayi Protein kinase domain containing protein 0.0365 0.0597 0.0597
Echinococcus multilocularis cyclin dependent kinase 1 0.027 0.0344 0.0344
Echinococcus multilocularis tyrosine protein kinase HCK 0.0207 0.018 0.018
Schistosoma mansoni serine/threonine protein kinase 0.0349 0.0553 0.0553
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0217 0.0206 0.0206
Trichomonas vaginalis glutamate synthase, putative 0.0361 0.0586 0.177
Brugia malayi Muscle positioning protein 4 0.0397 0.068 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0613 0.1251 0.3844
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0195 0.0148 0.0148
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0361 0.0586 0.0562
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0361 0.0586 0.177
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0149 0.0025 0.0032
Entamoeba histolytica serine/threonine protein kinase, putative 0.0178 0.0101 0.0401
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0361 0.0586 0.177
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0315 0.0465 0.0441
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.136 0.3225 0.3144
Leishmania major protein kinase, putative 0.0192 0.014 0.0115
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0767 0.1659 0.1659
Trichomonas vaginalis apoptosis inducing factor, putative 0.0361 0.0586 0.177
Schistosoma mansoni hypothetical protein 0.0231 0.0242 0.0242
Trichomonas vaginalis CMGC family protein kinase 0.0315 0.0465 0.1393
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0181 0.0111 0.0111
Brugia malayi Temporarily assigned gene name protein 59 0.0253 0.0301 0.0301
Echinococcus granulosus leucine rich repeat containing protein 4 0.0181 0.0111 0.0111
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0365 0.0597 0.0597
Echinococcus granulosus netrin receptor unc 5 0.0283 0.0379 0.0379
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.136 0.3225 0.3208
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0716 0.1522 0.1522
Echinococcus multilocularis cyclin dependent kinase 5 0.027 0.0344 0.0344
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0361 0.0586 0.0586
Echinococcus granulosus protein kinase 0.0347 0.055 0.055
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0984 0.223 0.223
Echinococcus multilocularis aurora kinase A 0.0267 0.0337 0.0337
Loa Loa (eye worm) hypothetical protein 0.0181 0.0111 0.0111
Schistosoma mansoni g1/s-specific cyclin C 0.1836 0.4481 0.4481
Leishmania major dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Echinococcus multilocularis dual specificity protein kinase clk2 0.0349 0.0553 0.0553
Echinococcus granulosus dual specificity 0.0315 0.0465 0.0465
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1382 0.4254
Loa Loa (eye worm) hypothetical protein 0.0409 0.0713 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.1081 0.2488 0.2488
Brugia malayi Protein kinase domain containing protein 0.0141 0.0003 0.0003
Echinococcus multilocularis casein kinase I alpha 0.0247 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0273 0.0354 0.0354
Schistosoma mansoni neuroglian 0.042 0.074 0.074
Echinococcus multilocularis slit 2 protein 0.0447 0.0813 0.0813
Echinococcus granulosus roundabout 2 0.042 0.074 0.074
Echinococcus granulosus cyclin dependent kinase 9 0.0172 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.027 0.0344 0.0344
Trichomonas vaginalis STE family protein kinase 0.0195 0.0148 0.0405
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1715 0.416 0.416
Brugia malayi Immunoglobulin I-set domain containing protein 0.0181 0.0111 0.0111
Onchocerca volvulus 0.0732 0.1567 0.7186
Echinococcus granulosus defective proboscis extension response 0.0716 0.1522 0.1522
Trypanosoma brucei protein kinase, putative 0.0292 0.0403 0.0379
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0217 0.0206 0.0206
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0229 0.0237 0.0237
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.136 0.3225 1
Echinococcus multilocularis epidermal growth factor receptor 0.0549 0.1081 0.1081
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0315 0.0465 0.0465
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0189 0.013 0.0106
Schistosoma mansoni notch 0.0397 0.068 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Loa Loa (eye worm) hypothetical protein 0.0315 0.0463 0.0463
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0399 0.0685 0.0685
Schistosoma mansoni hypothetical protein 0.0181 0.0111 0.0111
Brugia malayi hypothetical protein 0.0504 0.0963 0.0963
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0247 0.0283 0.0283
Schistosoma mansoni titin 0.0181 0.0111 0.0111
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0217 0.0206 0.0206
Echinococcus granulosus Immunoglobulin subtype 0.0217 0.0206 0.0206
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0292 0.0403 0.0403
Entamoeba histolytica hypothetical protein 0.0436 0.0782 0.3685
Schistosoma mansoni tyrosine kinase 0.0145 0.0015 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.049 0.0926 0.0926
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0138 0.0138
Echinococcus granulosus serine:threonine protein kinase 0.0259 0.0316 0.0316
Schistosoma mansoni tyrosine kinase 0.0347 0.0548 0.0548
Brugia malayi hypothetical protein 0.0732 0.1567 0.1567
Onchocerca volvulus 0.0149 0.0025 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.0101 0.026
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0217 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0145 0.0015 0.0015
Echinococcus multilocularis roundabout 2 0.1135 0.263 0.263
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.017 0.008 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Onchocerca volvulus Putative titin 0.0181 0.0111 0.0457
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0238 0.0261 0.0261
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0799 0.1743 0.8003
Brugia malayi Protein kinase domain containing protein 0.0492 0.0932 0.0932
Loa Loa (eye worm) TK/FER protein kinase 0.0496 0.0943 0.0943
Loa Loa (eye worm) hypothetical protein 0.1115 0.2576 0.2576
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0342 0.0536 0.0536
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.019 0.0134 0.0109
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0344 0.1017
Brugia malayi Fes/CIP4 homology domain containing protein 0.0232 0.0244 0.0244
Brugia malayi protein kinase C3,putative 0.0358 0.0577 0.0577
Trichomonas vaginalis CMGC family protein kinase 0.0204 0.017 0.0475
Onchocerca volvulus 0.0397 0.068 0.3085
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0361 0.0585 0.0562
Schistosoma mansoni hemicentin 0.0202 0.0166 0.0166
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0229 0.0237 0.0237
Onchocerca volvulus 0.0315 0.0463 0.2082
Echinococcus granulosus neurogenic locus notch protein 4 0.0397 0.068 0.068
Brugia malayi hypothetical protein 0.0217 0.0206 0.0206
Entamoeba histolytica protein kinase, putative 0.0267 0.0337 0.1539
Loa Loa (eye worm) TK protein kinase 0.0349 0.0553 0.0553
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0229 0.0237 0.012
Onchocerca volvulus 0.0181 0.0111 0.0457
Entamoeba histolytica protein kinase domain containing protein 0.0292 0.0403 0.1857
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0217 0.0206 0.0206
Onchocerca volvulus 0.0181 0.0111 0.0457
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2135 0.5271 0.5271
Onchocerca volvulus Peroxidasin homolog 0.0182 0.0113 0.0464
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0361 0.0586 0.0586
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.027 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Schistosoma mansoni serine/threonine protein kinase 0.046 0.0846 0.0846
Schistosoma mansoni protein kinase 0.0195 0.0148 0.0148
Echinococcus granulosus lachesin 0.0399 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0253 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0202 0.0167 0.0167
Echinococcus multilocularis down syndrome cell adhesion 0.0181 0.0111 0.0111
Echinococcus granulosus protein kinase C gamma type 0.0458 0.0842 0.0842
Echinococcus granulosus Immunoglobulin 0.0217 0.0206 0.0206
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0229 0.0237 0.0212
Echinococcus granulosus N chimaerin 0.017 0.008 0.008
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0495 0.0938 0.0938
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.027 0.0344 0.032
Echinococcus multilocularis cyclin dependent kinase 1 0.027 0.0344 0.0344
Brugia malayi Protein kinase domain containing protein 0.0149 0.0025 0.0025
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0412 0.072 0.072
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1238 0.2901 0.2901
Brugia malayi Protein kinase domain containing protein 0.0455 0.0835 0.0835
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0361 0.0586 0.177
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0247 0.0283 0.0283
Brugia malayi Disorganized muscle protein 1 0.0181 0.0111 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.042 0.074 0.074
Loa Loa (eye worm) hypothetical protein 0.0324 0.0487 0.0487
Leishmania major hypothetical protein, conserved 0.0361 0.0586 0.0562
Brugia malayi Immunoglobulin I-set domain containing protein 0.042 0.074 0.074
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.136 0.3225 0.2803
Echinococcus granulosus tyrosine protein kinase Src42A 0.0211 0.0189 0.0189
Entamoeba histolytica protein kinase, putative 0.0277 0.0365 0.1671
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0189 0.013 0.013
Toxoplasma gondii NADPH-glutathione reductase 0.136 0.3225 0.3208
Entamoeba histolytica protein kinase, putative 0.0163 0.0063 0.0219
Echinococcus multilocularis peroxidasin 0.0399 0.0687 0.0687
Giardia lamblia Kinase, CMGC CLK 0.0349 0.0553 0.1364
Brugia malayi Protein kinase domain containing protein 0.1238 0.2901 0.2901
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0213 0.0195 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.063 0.1296 0.3983
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0613 0.1251 0.1251
Onchocerca volvulus 0.0397 0.068 0.3085
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0181 0.0111 0.0111
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0361 0.0585 0.0562
Brugia malayi SH2 domain containing protein 0.0149 0.0025 0.0025
Entamoeba histolytica thioredoxin reductase, putative 0.0361 0.0586 0.2737
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0025 0.0025
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0267 0.0337 0.0337
Schistosoma mansoni protein kinase 0.0831 0.1828 0.1828
Trypanosoma cruzi casein kinase, putative 0.0247 0.0283 0.0259
Schistosoma mansoni vav2 0.0187 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0397 0.068 0.068
Brugia malayi Myb-like DNA-binding domain containing protein 0.0181 0.0111 0.0111
Trichomonas vaginalis CMGC family protein kinase 0.027 0.0344 0.1017
Brugia malayi basement membrane proteoglycan precursor 0.0217 0.0206 0.0206
Leishmania major NADH dehydrogenase, putative 0.0361 0.0586 0.0562
Schistosoma mansoni titin 0.0181 0.0111 0.0111
Brugia malayi notch-like transmembrane receptor 0.0397 0.068 0.068
Loa Loa (eye worm) cyclin C 0.1836 0.4481 0.4481
Schistosoma mansoni rap gtpase-activating protein 0.0253 0.0301 0.0301
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.027 0.0344 0.0344
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0267 0.0337 0.0222
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0217 0.0206 0.0206
Leishmania major acetoin dehydrogenase e3 component-like protein 0.136 0.3225 0.3208
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0355 0.0571 0.0547
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0217 0.0206 0.0206
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0933 0.2097 0.2097
Schistosoma mansoni protein kinase 0.0149 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0253 0.0301 0.0301
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0397 0.068 0.3085
Schistosoma mansoni ephrin receptor 0.0219 0.021 0.021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0232 0.0244 0.0244
Schistosoma mansoni hypothetical protein 0.0361 0.0586 0.0586
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0372 0.0615 0.0615
Schistosoma mansoni serine/threonine protein kinase 0.0306 0.044 0.044
Brugia malayi Protein kinase domain containing protein 0.0484 0.0909 0.0909
Trichomonas vaginalis CMGC family protein kinase 0.019 0.0134 0.0362
Onchocerca volvulus 0.0149 0.0025 0.0057
Schistosoma mansoni hypothetical protein 0.0397 0.068 0.068
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0322 0.0947
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0361 0.0586 0.177
Trypanosoma brucei rac serine-threonine kinase, putative 0.0663 0.1382 0.1361
Echinococcus granulosus tyrosine protein kinase Srms 0.0616 0.1259 0.1259
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0349 0.0553 0.0529
Brugia malayi Protein kinase c protein 2 0.0263 0.0326 0.0326
Echinococcus multilocularis protein jagged 1 0.0397 0.068 0.068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.136 0.3225 0.3208
Echinococcus granulosus tyrosine protein kinase shark 0.0393 0.0671 0.0671

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 100 uM Concentration to inhibit 3' processing of wild type Human immuno deficiency virus-1 integrase ChEMBL. 15743192
IC50 (binding) > 100 uM Concentration to inhibit strand transfer of wild type Human immuno deficiency virus-1 integrase ChEMBL. 15743192
IC50 (binding) > 100 uM Concentration to inhibit 3' processing of wild type Human immuno deficiency virus-1 integrase ChEMBL. 15743192
IC50 (binding) > 100 uM Concentration to inhibit strand transfer of wild type Human immuno deficiency virus-1 integrase ChEMBL. 15743192

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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