Detailed information for compound 313077

Basic information

Technical information
  • TDR Targets ID: 313077
  • Name: 1-[2-[[4-[(4-fluorophenyl)methyl]piperidin-1- yl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
  • MW: 453.592 | Formula: C27H36FN3O2
  • H donors: 2 H acceptors: 1 LogP: 5.45 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)NC(=O)NC1CCCCC1CN1CCC(CC1)Cc1ccc(cc1)F
  • InChi: 1S/C27H36FN3O2/c1-33-25-7-4-6-24(18-25)29-27(32)30-26-8-3-2-5-22(26)19-31-15-13-21(14-16-31)17-20-9-11-23(28)12-10-20/h4,6-7,9-12,18,21-22,26H,2-3,5,8,13-17,19H2,1H3,(H2,29,30,32)
  • InChiKey: YLLQTYFPCPQMDK-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-[2-[[4-[(4-fluorophenyl)methyl]-1-piperidyl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
  • 1-[2-[[4-[(4-fluorophenyl)methyl]-1-piperidinyl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
  • 1-[2-[[4-(4-fluorobenzyl)piperidino]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea
  • 1-[2-[[4-(4-fluorobenzyl)-1-piperidyl]methyl]cyclohexyl]-3-(3-methoxyphenyl)urea

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens chemokine (C-C motif) receptor 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major protein kinase, putative 0.031 0.079 0.0714
Giardia lamblia Kinase, CMGC CLK 0.031 0.079 0.1937
Entamoeba histolytica protein kinase, putative 0.0325 0.0849 0.401
Trypanosoma brucei SNF1-related protein kinases, putative 0.0157 0.0184 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0675 0.067
Brugia malayi Temporarily assigned gene name protein 59 0.0226 0.0457 0.0452
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0673 0.2234 0.223
Trichomonas vaginalis CAMK family protein kinase 0.023 0.0472 0.1288
Brugia malayi ephrin receptor 1 precursor 0.0127 0.0063 0.0058
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0405 0.1168 0.1164
Echinococcus multilocularis dual specificity protein kinase clk2 0.031 0.079 0.0785
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0242 0.0519 0.1439
Loa Loa (eye worm) hypothetical protein 0.023 0.0472 0.0472
Loa Loa (eye worm) CDC7 protein kinase 0.0181 0.0277 0.0277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0299 0.0748 0.0743
Echinococcus multilocularis ephrin type A receptor 4 A 0.0195 0.0335 0.033
Loa Loa (eye worm) hypothetical protein 0.0152 0.0163 0.0163
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0489 0.1502 0.1497
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Giardia lamblia Glutamate synthase 0.0242 0.0519 0.1023
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0226 0.0457 0.0378
Echinococcus granulosus Glutaredoxin protein 5 0.025 0.0552 0.0548
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0911 0.3177 1
Echinococcus multilocularis serine:threonine protein kinase 0.023 0.0472 0.0468
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0333 0.0328
Loa Loa (eye worm) hypothetical protein 0.0226 0.0457 0.0457
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Onchocerca volvulus 0.0147 0.0144 0.0508
Loa Loa (eye worm) TK/FAK protein kinase 0.0589 0.1898 0.1898
Brugia malayi GCC2 and GCC3 family protein 0.0756 0.2562 0.2558
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0242 0.0519 0.0515
Schistosoma mansoni hypothetical protein 0.0152 0.0163 0.0158
Echinococcus multilocularis protein kinase c epsilon type 0.0412 0.1195 0.1191
Brugia malayi C1-like domain containing protein 0.0439 0.1304 0.1299
Brugia malayi Protein kinase domain containing protein 0.0311 0.0793 0.0788
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0877 0.3041 0.3037
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Echinococcus granulosus nervana 2 0.025 0.0552 0.0548
Loa Loa (eye worm) hypothetical protein 0.0226 0.0457 0.0457
Onchocerca volvulus 0.0266 0.0614 0.2162
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0157 0.0184 0.0103
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0242 0.0519 0.0441
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Brugia malayi hypothetical protein 0.0133 0.0086 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1514 0.1509
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0242 0.0519 0.1439
Echinococcus multilocularis dual specificity 0.028 0.0672 0.0667
Onchocerca volvulus 0.0129 0.0071 0.0251
Entamoeba histolytica protein kinase, putative 0.0145 0.0133 0.061
Brugia malayi Thioredoxin reductase 0.2629 1 1
Echinococcus multilocularis slit 2 protein 0.031 0.0792 0.0788
Echinococcus multilocularis serine:threonine protein kinase 38 0.0325 0.0849 0.0844
Echinococcus multilocularis myosin iiia 0.017 0.0236 0.0231
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0167 0.0223 0.0143
Trypanosoma brucei protein kinase, putative 0.0177 0.0261 0.018
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0299 0.0748 0.0743
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0309 0.0786 0.0786
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0129 0.0071 0.0071
Mycobacterium tuberculosis Probable oxidoreductase 0.0911 0.3177 0.2803
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0242 0.0519 0.1439
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0331 0.0875 0.0799
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0237 0.0501 0.0496
Entamoeba histolytica casein kinase, putative 0.0219 0.0429 0.2012
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0474 0.1443 0.1439
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Loa Loa (eye worm) hypothetical protein 0.0289 0.0706 0.0706
Brugia malayi Protein kinase domain containing protein 0.0181 0.0277 0.0272
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Echinococcus multilocularis cyclin dependent kinase 0.0239 0.051 0.0505
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0164 0.021 0.021
Schistosoma mansoni tyrosine kinase 0.0607 0.1972 0.1968
Echinococcus granulosus mitogen activated protein kinase 14 0.0321 0.0834 0.0829
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Brugia malayi RhoGAP domain containing protein 0.0151 0.016 0.0155
Loa Loa (eye worm) AGC/PKN protein kinase 0.0587 0.189 0.189
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0316 0.0814 0.062
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0152 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0206 0.0377 0.0377
Entamoeba histolytica protein kinase, putative 0.0259 0.0589 0.2776
Brugia malayi Protein kinase domain containing protein 0.0133 0.0086 0.0081
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0169 0.0228 0.0148
Brugia malayi Immunoglobulin I-set domain containing protein 0.017 0.0236 0.0231
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0405 0.1168 0.1164
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0242 0.0519 0.0441
Giardia lamblia Kinase, CK1 Casein kinase 0.0219 0.0429 0.0716
Schistosoma mansoni nephrin related 0.0152 0.0163 0.0158
Onchocerca volvulus Slit protein homolog 0.031 0.0792 0.279
Schistosoma mansoni protein kinase 0.0446 0.1331 0.1326
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0366 0.0361
Leishmania major hypothetical protein, conserved 0.0242 0.0519 0.0441
Echinococcus granulosus c-Jun N-terminal kinases 0.0534 0.1678 0.1674
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.051 0.1583 0.1579
Brugia malayi EGF-like domain containing protein 0.031 0.0792 0.0788
Echinococcus multilocularis cyclin dependent kinase 19 0.0871 0.3018 0.3015
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.017 0.0236 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.0874 0.0869
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0546 0.1727 0.1727
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0242 0.0519 0.1439
Schistosoma mansoni titin 0.0129 0.0071 0.0066
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0534 0.1678 0.1678
Schistosoma mansoni cell adhesion molecule 0.0147 0.0144 0.0139
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0157 0.0184 0.0103
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0219 0.0429 0.0429
Echinococcus granulosus protein jagged 2 0.0266 0.0614 0.0609
Trichomonas vaginalis glutamate synthase, putative 0.0242 0.0519 0.1439
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Entamoeba histolytica serine/threonine protein kinase, putative 0.0157 0.0184 0.0851
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0448 0.1341 0.1341
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0228 0.0502
Loa Loa (eye worm) TK protein kinase 0.0376 0.1051 0.1051
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0519 0.1619 0.1619
Echinococcus granulosus netrin receptor unc 5 0.021 0.0395 0.039
Toxoplasma gondii casein kinase I 0.0219 0.0429 0.035
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0325 0.0849 0.0844
Loa Loa (eye worm) AUR protein kinase 0.0237 0.0501 0.0501
Brugia malayi kettin 0.0129 0.0071 0.0066
Entamoeba histolytica PH domain containing protein kinase, putative 0.0243 0.0525 0.2468
Toxoplasma gondii CMGC kinase, CK2 family 0.0202 0.036 0.028
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0436 0.1291 0.1286
Entamoeba histolytica cell division protein kinase 2, putative 0.0248 0.0542 0.2553
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0169 0.0228 0.0148
Onchocerca volvulus 0.0153 0.0167 0.0588
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.051 0.0505
Echinococcus multilocularis neuroglian 0.0299 0.0748 0.0743
Schistosoma mansoni hypothetical protein 0.0147 0.0144 0.0139
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Echinococcus granulosus thioredoxin glutathione reductase 0.2629 1 1
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0203 0.0366 0.0286
Echinococcus granulosus neuroglian 0.0638 0.2095 0.2091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0292 0.0718 0.0713
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0669 0.2217 0.2213
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Trichomonas vaginalis glutathione reductase, putative 0.0911 0.3177 1
Loa Loa (eye worm) CAMK protein kinase 0.0213 0.0406 0.0406
Toxoplasma gondii histone kinase SNF1, putative 0.0157 0.0184 0.0103
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.025 0.0552 0.0548
Schistosoma mansoni netrin receptor unc5 0.021 0.0395 0.039
Brugia malayi Protein kinase domain containing protein 0.0589 0.1898 0.1894
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0163 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.025 0.0245
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0712 0.2388 0.2384
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0672 0.1931
Onchocerca volvulus 0.0266 0.0614 0.2162
Schistosoma mansoni serine/threonine protein kinase 0.0657 0.2167 0.2163
Echinococcus multilocularis serine:threonine protein kinase 3 0.0519 0.1619 0.1614
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0188 0.0306 0.0301
Entamoeba histolytica protein kinase, putative 0.0246 0.0538 0.2531
Schistosoma mansoni tyrosine kinase 0.0423 0.1241 0.1236
Onchocerca volvulus Serine\/threonine kinase homolog 0.0331 0.0874 0.3076
Brugia malayi Kinase associated domain 1 family protein 0.0206 0.0377 0.0372
Onchocerca volvulus 0.0129 0.0073 0.0258
Plasmodium falciparum NIMA related kinase 1 0.0274 0.0649 0.0572
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0911 0.3177 0.3033
Brugia malayi Protein kinase domain containing protein 0.0645 0.2121 0.2117
Trichomonas vaginalis CAMK family protein kinase 0.0255 0.0571 0.1605
Brugia malayi serine/threonine-protein kinase plk-2 0.0546 0.1727 0.1722
Schistosoma mansoni serine/threonine protein kinase 0.0436 0.1291 0.1286
Plasmodium falciparum serine/threonine protein kinase KIN 0.0157 0.0184 0.0103
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0144 0.0139
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0911 0.3177 0.3121
Brugia malayi EGF-like domain containing protein 0.0266 0.0614 0.0609
Echinococcus multilocularis peroxidasin 0.0281 0.0677 0.0672
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0474 0.1443 0.1439
Loa Loa (eye worm) cyclin C 0.1268 0.4598 0.4598
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0309 0.0787 0.0782
Brugia malayi hypothetical protein 0.0226 0.0457 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0184 0.0179
Schistosoma mansoni hypothetical protein 0.0152 0.0163 0.0158
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0712 0.2388 0.8406
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0223 0.0218
Echinococcus granulosus serine:threonine kinase SAD 1 0.0157 0.0184 0.0179
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Entamoeba histolytica protein kinase, putative 0.0237 0.0501 0.2355
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0281 0.0675 0.2376
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Echinococcus granulosus serine threonine protein kinase nrc 0.0316 0.0814 0.0809
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0242 0.0519 0.1439
Echinococcus multilocularis mitogen activated protein kinase 14 0.0321 0.0834 0.0829
Echinococcus multilocularis basement membrane specific heparan sulfate 0.051 0.1583 0.1579
Trichomonas vaginalis CAMK family protein kinase 0.0554 0.1759 0.5432
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0675 0.067
Loa Loa (eye worm) cyclin domain-containing protein 0.0633 0.2074 0.2074
Echinococcus granulosus cGMP dependent protein kinase 1 0.017 0.0233 0.0228
Brugia malayi Tyrosine-protein kinase abl-1 0.019 0.0314 0.0309
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0228 0.0464 0.0385
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0309 0.0787 0.0782
Schistosoma mansoni septate junction protein 0.0281 0.0675 0.067
Schistosoma mansoni serine/threonine protein kinase 0.0964 0.3387 0.3383
Schistosoma mansoni hypothetical protein 0.0206 0.0377 0.0372
Echinococcus granulosus peroxidasin 0.0281 0.0677 0.0672
Echinococcus multilocularis notch 0.0266 0.0614 0.0609
Leishmania major casein kinase, putative 0.0219 0.0429 0.035
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0492 0.1514 0.1509
Schistosoma mansoni septate junction protein 0.0266 0.0614 0.0609
Schistosoma mansoni myosin-binding protein-related 0.0147 0.0144 0.0139
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0242 0.0519 0.1439
Trypanosoma brucei trypanothione reductase 0.2629 1 1
Echinococcus granulosus protein kinase c epsilon type 0.0412 0.1195 0.1191
Schistosoma mansoni ste20-related kinase 0.0414 0.1203 0.1199
Brugia malayi probable protein kinase 0.0535 0.1683 0.1679
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0436 0.1291 0.1286
Trichomonas vaginalis CK1 family protein kinase 0.0219 0.0429 0.1147
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0242 0.0519 0.1439
Loa Loa (eye worm) hypothetical protein 0.0528 0.1656 0.1656
Echinococcus granulosus N chimaerin 0.0151 0.016 0.0155
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0448 0.1341 0.1336
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.1727 0.5328
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0321 0.0834 0.0758
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0203 0.0366 0.0361
Schistosoma mansoni septate junction protein 0.0152 0.0163 0.0158
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0242 0.0519 0.0441
Echinococcus granulosus titin 0.0129 0.0071 0.0066
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0246 0.0538 0.046
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0462 0.1396 0.1391
Loa Loa (eye worm) hypothetical protein 0.0264 0.0608 0.0608
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Onchocerca volvulus Serine\/threonine kinase homolog 0.0546 0.1727 0.6079
Brugia malayi p70 ribosomal S6 kinase beta 0.0575 0.1842 0.1838
Entamoeba histolytica p21-activated kinase 0.0188 0.0308 0.1437
Loa Loa (eye worm) AGC/PKA protein kinase 0.0228 0.0464 0.0464
Giardia lamblia Kinase, NEK 0.0274 0.0649 0.1462
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0228 0.0223
Loa Loa (eye worm) Notch2 0.0266 0.0614 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0712 0.2388 0.2384
Leishmania major protein kinase, putative 0.017 0.0236 0.0155
Loa Loa (eye worm) hypothetical protein 0.0157 0.0184 0.0184
Echinococcus granulosus mitogen activated protein kinase 0.0169 0.0228 0.0223
Schistosoma mansoni cell adhesion molecule 0.068 0.226 0.2256
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0409 0.1183 0.1179
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0233 0.0228
Schistosoma mansoni hypothetical protein 0.0226 0.0457 0.0452
Entamoeba histolytica protein kinase, putative 0.0206 0.0376 0.1762
Plasmodium falciparum glycogen synthase kinase 3 0.0259 0.0589 0.0512
Entamoeba histolytica protein kinase domain containing protein 0.0246 0.0538 0.2531
Schistosoma mansoni slit 0.0266 0.0616 0.0611
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0321 0.0834 0.0758
Loa Loa (eye worm) hypothetical protein 0.079 0.2699 0.2699
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0242 0.0519 0.0515
Loa Loa (eye worm) hypothetical protein 0.0281 0.0675 0.0675
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.1727 0.5328
Schistosoma mansoni tyrosine kinase 0.0583 0.1873 0.1869
Trichomonas vaginalis CAMK family protein kinase 0.0438 0.1299 0.3949
Entamoeba histolytica PH domain containing protein kinase, putative 0.0243 0.0525 0.2468
Loa Loa (eye worm) hypothetical protein 0.0203 0.0366 0.0366
Loa Loa (eye worm) SRC-1 0.0309 0.0787 0.0787
Echinococcus multilocularis serine:threonine protein kinase N2 0.0262 0.06 0.0596
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0999 0.3527 0.3523
Echinococcus granulosus tyrosine protein kinase Srms 0.0549 0.1739 0.1735
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0259 0.0589 0.0589
Echinococcus granulosus dual specificity 0.028 0.0672 0.0667
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0242 0.0519 0.0515
Schistosoma mansoni vav2 0.0167 0.0221 0.0216
Schistosoma mansoni basigin related 0.0152 0.0163 0.0158
Echinococcus granulosus titin 0.0213 0.0406 0.0401
Echinococcus granulosus growth factor receptor bound protein 2 0.0126 0.006 0.0055
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0228 0.0464 0.0263
Echinococcus multilocularis serine:threonine protein kinase 0.023 0.0472 0.0468
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0911 0.3177 0.2803
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0203 0.0366 0.0361
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0203 0.0366 0.0361
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.0538 0.0533
Brugia malayi cell division control protein 2 homolog 0.0239 0.051 0.0505
Echinococcus granulosus tyrosine protein kinase HCK 0.0185 0.0294 0.0289
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0242 0.0519 0.0441
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0133 0.0086 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Trypanosoma cruzi casein kinase, putative 0.0219 0.0429 0.035
Echinococcus multilocularis neurogenic locus protein delta 0.0266 0.0614 0.0609
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0673 0.2234 0.2234
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.028 0.0672 0.0595
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0203 0.0366 0.0361
Entamoeba histolytica protein kinase, putative 0.0167 0.0223 0.1037
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0299 0.0748 0.0743
Onchocerca volvulus Neurogenic locus notch homolog 0.0266 0.0614 0.2162
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0252 0.0559 0.0554
Trypanosoma brucei NADH dehydrogenase 0.0242 0.0519 0.0441
Brugia malayi Protein kinase domain containing protein 0.0164 0.021 0.0205
Echinococcus granulosus serine:threonine protein kinase 0.023 0.0472 0.0468
Echinococcus granulosus cyclin dependent kinase 1 0.0239 0.051 0.0505
Trichomonas vaginalis CMGC family protein kinase 0.0239 0.051 0.1409
Echinococcus multilocularis mitogen activated protein kinase 11 0.0321 0.0834 0.0829
Echinococcus granulosus Protein kinase C brain isozyme 0.0492 0.1514 0.1509
Schistosoma mansoni hypothetical protein 0.0129 0.0071 0.0066
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0228 0.0464 0.0385
Loa Loa (eye worm) hypothetical protein 0.0152 0.0163 0.0163
Trichomonas vaginalis glutamate synthase, putative 0.0242 0.0519 0.1439
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0501 0.1379
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0242 0.0519 0.0319
Schistosoma mansoni slit 0.0129 0.0073 0.0068
Brugia malayi Protein kinase domain containing protein 0.0167 0.0223 0.0218
Plasmodium falciparum apical sushi protein 0.049 0.1507 0.1437
Echinococcus granulosus ephrin type A receptor 4 A 0.0195 0.0335 0.033
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0195 0.0333 0.0328
Echinococcus granulosus tyrosine protein kinase Src64B 0.0309 0.0787 0.0782
Echinococcus multilocularis serine threonine protein kinase 0.0407 0.1178 0.1173
Loa Loa (eye worm) thioredoxin reductase 0.2629 1 1
Toxoplasma gondii AGC kinase 0.0575 0.1842 0.1775
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0442 0.1316 0.1312
Brugia malayi Cyclin C 0.1268 0.4598 0.4595
Echinococcus multilocularis casein kinase ii subunit alpha 0.0202 0.036 0.0355
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0246 0.0538 0.046
Echinococcus granulosus protein tyrosine kinase 0.0583 0.1873 0.1869
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0167 0.0223 0.0143
Brugia malayi Immunoglobulin I-set domain containing protein 0.0528 0.1656 0.1652
Schistosoma mansoni serine/threonine protein kinase 0.0213 0.0406 0.0401
Echinococcus multilocularis mitogen activated protein kinase 0.0169 0.0228 0.0223
Entamoeba histolytica protein kinase 2, putative 0.0316 0.0814 0.3843
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0129 0.0071 0.0066
Echinococcus granulosus aurora kinase A 0.0237 0.0501 0.0496
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0202 0.036 0.036
Echinococcus granulosus defective proboscis extension response 0.051 0.1583 0.1579
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.1727 0.5328
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Onchocerca volvulus 0.0181 0.0277 0.0975
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0242 0.0519 0.0515
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0409 0.1183 0.1179
Echinococcus multilocularis expressed protein 0.0167 0.0223 0.0218
Loa Loa (eye worm) CMGC/CLK protein kinase 0.031 0.079 0.079
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0237 0.0501 0.03
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0546 0.1727 0.1722
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0501 0.0496
Entamoeba histolytica cyclin C, putative 0.0642 0.211 1
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0246 0.0538 0.0538
Brugia malayi serine/threonine-protein kinase PAK 7 0.0468 0.142 0.1416
Trypanosoma brucei Casein kinase II 0.0202 0.036 0.028
Loa Loa (eye worm) hypothetical protein 0.0377 0.1055 0.1055
Trichomonas vaginalis apoptosis inducing factor, putative 0.0242 0.0519 0.1439
Loa Loa (eye worm) hypothetical protein 0.051 0.1585 0.1585
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0464 0.0459
Brugia malayi Animal haem peroxidase family protein 0.0129 0.0071 0.0066
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0213 0.0406 0.0406
Onchocerca volvulus 0.0591 0.1906 0.6709
Schistosoma mansoni notch 0.0266 0.0614 0.0609
Brugia malayi SH2 domain containing protein 0.0133 0.0086 0.0081
Brugia malayi notch-like transmembrane receptor 0.0266 0.0614 0.0609
Trichomonas vaginalis AGC family protein kinase 0.0274 0.0649 0.1858
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Echinococcus multilocularis aurora kinase A 0.0237 0.0501 0.0496
Echinococcus granulosus cGMP dependent protein kinase 0.017 0.0233 0.0228
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0277 0.0658
Onchocerca volvulus 0.0129 0.0071 0.0251
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0309 0.0787 0.0782
Brugia malayi Leucine Rich Repeat family protein 0.0129 0.0073 0.0068
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0796 0.2722 0.2718
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0242 0.0519 0.2444
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0242 0.0519 0.1439
Echinococcus multilocularis down syndrome cell adhesion 0.0129 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Plasmodium vivax serine/threonine kinase-1, putative 0.031 0.079 0.0596
Loa Loa (eye worm) animal heme peroxidase 0.0129 0.0071 0.0071
Schistosoma mansoni tyrosine kinase 0.0367 0.1019 0.1014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0911 0.3177 0.3174
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0203 0.0366 0.0163
Schistosoma mansoni protein kinase 0.0389 0.1105 0.11
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Echinococcus granulosus fibropellin Ia 0.0266 0.0614 0.0609
Schistosoma mansoni hypothetical protein 0.0129 0.0071 0.0066
Brugia malayi Calcium binding EGF domain containing protein 0.0266 0.0614 0.0609
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0242 0.0519 0.0441
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0911 0.3177 0.3121
Entamoeba histolytica protein kinase domain containing protein 0.0409 0.1183 0.5598
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0626 0.2045 0.2041
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0575 0.1842 0.1842
Schistosoma mansoni tyrosine kinase 0.0489 0.1502 0.1497
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0226 0.0457 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0325 0.0849 0.0844
Echinococcus granulosus tyrosine protein kinase Src42A 0.0188 0.0306 0.0301
Echinococcus granulosus titin 0.0129 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Brugia malayi Prion-like- 0.0129 0.0071 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0184 0.0179
Echinococcus multilocularis NCK adaptor protein 0.0126 0.006 0.0055
Echinococcus multilocularis PAK box P21 Rho binding 0.0129 0.0073 0.0067
Loa Loa (eye worm) hypothetical protein 0.0152 0.0163 0.0163
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0246 0.0538 0.046
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0242 0.0519 0.1439
Brugia malayi Immunoglobulin I-set domain containing protein 0.0496 0.1531 0.1526
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0495 0.1525 0.152
Loa Loa (eye worm) hypothetical protein 0.0281 0.0674 0.0674
Brugia malayi protein-tyrosine kinase 0.0252 0.0559 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Echinococcus granulosus nephrin 0.0147 0.0144 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0639 0.0634
Brugia malayi glutamate synthase 0.0242 0.0519 0.0515
Loa Loa (eye worm) TK protein kinase 0.0311 0.0793 0.0793
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Onchocerca volvulus 0.049 0.1507 0.5306
Brugia malayi map kinase activated protein kinase protein 2 0.0796 0.2722 0.2718
Echinococcus granulosus titin 0.0129 0.0071 0.0066
Echinococcus granulosus Immunoglobulin 0.0152 0.0163 0.0158
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0321 0.0834 0.0834
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0321 0.0834 0.0758
Loa Loa (eye worm) hypothetical protein 0.0545 0.1726 0.1726
Echinococcus multilocularis Immunoglobulin 0.051 0.1583 0.1579
Plasmodium falciparum protein kinase 5 0.0239 0.051 0.0432
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0124 0.0052 0.0047
Schistosoma mansoni tyrosine kinase 0.0351 0.0952 0.0947
Schistosoma mansoni notch 0.0266 0.0614 0.0609
Echinococcus multilocularis death associated protein kinase 1 0.0899 0.3128 0.3125
Echinococcus multilocularis twitchin 0.0195 0.0333 0.0328
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Echinococcus multilocularis Immunoglobulin 0.051 0.1583 0.1579
Echinococcus granulosus casein kinase ii subunit alpha 0.0202 0.036 0.0355
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0147 0.0144 0.0139
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0546 0.1727 0.1658
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0237 0.0501 0.2355
Onchocerca volvulus 0.0133 0.0086 0.0301
Entamoeba histolytica protein kinase, putative 0.0129 0.0073 0.032
Onchocerca volvulus 0.0147 0.0144 0.0508
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0157 0.0184 0.0179
Toxoplasma gondii rhoptry neck protein RON9 0.049 0.1507 0.1437
Echinococcus multilocularis roundabout 2 0.0809 0.2772 0.2768
Treponema pallidum NADH oxidase 0.0911 0.3177 1
Echinococcus granulosus calcium dependent protein kinase 0.0137 0.0104 0.0099
Entamoeba histolytica PH domain containing protein kinase, putative 0.0331 0.0875 0.4132
Schistosoma mansoni titin 0.0213 0.0406 0.0401
Trypanosoma cruzi polo-like protein kinase, putative 0.0546 0.1727 0.1658
Onchocerca volvulus Tyrosine kinase homolog 0.0826 0.284 1
Brugia malayi Delta serrate ligand family protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0129 0.0071 0.0071
Trypanosoma cruzi cdc2-related kinase 1 0.0239 0.051 0.0432
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Brugia malayi Protein kinase domain containing protein 0.0741 0.2502 0.2498
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0152 0.0163 0.0158
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0367 0.1019 0.1014
Schistosoma mansoni titin 0.0129 0.0071 0.0066
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0911 0.3177 1
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0237 0.0501 0.2355
Echinococcus granulosus cGMP dependent protein kinase 1 0.017 0.0233 0.0228
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.031 0.079 0.0714
Loa Loa (eye worm) hypothetical protein 0.0241 0.0515 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0639 0.0634
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Toxoplasma gondii EGF family domain-containing protein 0.0266 0.0614 0.0536
Loa Loa (eye worm) hypothetical protein 0.0289 0.0706 0.0706
Echinococcus granulosus nervana 2 0.025 0.0552 0.0548
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0365 0.1009 0.1009
Brugia malayi Cyclin, N-terminal domain containing protein 0.0633 0.2074 0.2069
Echinococcus granulosus cyclin 0.0633 0.2074 0.2069
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.028 0.0672 0.0595
Loa Loa (eye worm) disorganized muscle protein 1 0.0129 0.0071 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0184 0.0179
Echinococcus granulosus dual specificity 0.028 0.0672 0.0667
Brugia malayi Protein kinase domain containing protein 0.031 0.079 0.0785
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.048 0.1313
Plasmodium falciparum protein serine/threonine kinase-1 0.031 0.079 0.0714
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0226 0.0457 0.0452
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0446 0.1331 0.1326
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Schistosoma mansoni roundabout 0.0281 0.0675 0.067
Onchocerca volvulus 0.049 0.1507 0.5306
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) AUR protein kinase 0.0237 0.0501 0.0501
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0661 0.2187 0.2183
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0202 0.036 0.0157
Echinococcus multilocularis 0.0244 0.0528 0.0524
Loa Loa (eye worm) hypothetical protein 0.0281 0.0675 0.0675
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.1195 0.1191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0144 0.0139
Echinococcus granulosus tyrosine protein kinase shark 0.0351 0.0952 0.0947
Schistosoma mansoni serine/threonine protein kinase 0.028 0.0672 0.0667
Echinococcus multilocularis tyrosine protein kinase Abl 0.019 0.0314 0.0309
Schistosoma mansoni septate junction protein 0.0281 0.0675 0.067
Echinococcus granulosus cyclin dependent kinase 9 0.012 0.0037 0.0032
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.031 0.079 0.0714
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0292 0.0718 0.0713
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0172 0.0243 0.0243
Schistosoma mansoni Neurotrimin precursor (hNT) 0.051 0.1583 0.1579
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0281 0.0675 0.067
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0325 0.0849 0.0844
Trichomonas vaginalis AGC family protein kinase 0.0164 0.021 0.0444
Brugia malayi Protein kinase domain containing protein 0.0871 0.3018 0.3015
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0242 0.0519 0.0515
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.028 0.067 0.1926
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0203 0.0366 0.0361
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0226 0.0457 0.0452
Schistosoma mansoni serine/threonine-protein kinase 0.0331 0.0875 0.087
Plasmodium falciparum thioredoxin reductase 0.0911 0.3177 0.3121
Schistosoma mansoni glutamate synthase 0.0242 0.0519 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0911 0.3177 1
Giardia lamblia Kinase, CMGC GSK 0.0259 0.0589 0.1259
Brugia malayi Protein kinase domain containing protein 0.0607 0.1972 0.1968
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Loa Loa (eye worm) projectin 0.0147 0.0144 0.0144
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0157 0.0184 0.0184
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0203 0.0366 0.0163
Loa Loa (eye worm) hypothetical protein 0.0377 0.1055 0.1055
Loa Loa (eye worm) hypothetical protein 0.0281 0.0677 0.0677
Trypanosoma cruzi aurora B kinase, putative 0.0237 0.0501 0.0422
Onchocerca volvulus Peroxidasin homolog 0.0129 0.0073 0.0258
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Echinococcus multilocularis tyrosine protein kinase Blk 0.0252 0.0559 0.0554
Brugia malayi Prion-like- 0.0129 0.0071 0.0066
Echinococcus multilocularis epidermal growth factor receptor 0.0489 0.1502 0.1497
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0232 0.048 0.0475
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0331 0.0874 0.0874
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0299 0.0748 0.0743
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Echinococcus multilocularis neurogenic locus notch protein 0.0266 0.0614 0.0609
Schistosoma mansoni tyrosine kinase 0.0309 0.0787 0.0782
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0242 0.0519 0.0441
Schistosoma mansoni cell polarity protein 0.0266 0.0614 0.0609
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0589 0.1665
Loa Loa (eye worm) AGC/NDR protein kinase 0.0325 0.0849 0.0849
Echinococcus granulosus twitchin 0.0704 0.2357 0.2353
Brugia malayi hypothetical protein 0.0152 0.0163 0.0158
Brugia malayi intracellular kinase 0.0259 0.0589 0.0585
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0239 0.051 0.0432
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0162 0.0202 0.0197
Loa Loa (eye worm) hypothetical protein 0.0281 0.0674 0.0674
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0281 0.0675 0.0675
Plasmodium vivax thioredoxin reductase, putative 0.2629 1 1
Giardia lamblia Kinase, STE STE20 0.0173 0.0247 0.0102
Echinococcus multilocularis casein kinase I delta 0.0219 0.0429 0.0424
Brugia malayi protein kinase C II. 0.0412 0.1195 0.1191
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0129 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0206 0.0377 0.0372
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0367 0.1019 0.1014
Schistosoma mansoni protein kinase C mu 0.0439 0.1304 0.1299
Trichomonas vaginalis AGC family protein kinase 0.0333 0.0881 0.2605
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0911 0.3177 0.3121
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0242 0.0519 0.0319
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0163 0.0158
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0173 0.0247 0.0242
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Trypanosoma cruzi Protein kinase B 0.0331 0.0875 0.0799
Schistosoma mansoni disulfide oxidoreductase 0.0242 0.0519 0.0515
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0871 0.3018 0.3018
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0796 0.2722 0.2718
Brugia malayi casein kinase 1, delta 0.0219 0.0429 0.0424
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0259 0.0589 0.0512
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0242 0.0519 0.0515
Echinococcus granulosus casein kinase i 0.0219 0.0429 0.0424
Echinococcus multilocularis glutamate synthase 0.0242 0.0519 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0325 0.0849 0.0844
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0242 0.0519 0.0515
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0309 0.0787 0.0782
Trypanosoma cruzi hypothetical protein, conserved 0.0242 0.0519 0.0441
Echinococcus multilocularis casein kinase I alpha 0.0219 0.0429 0.0424
Leishmania major protein kinase, putative 0.031 0.079 0.0714
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0219 0.0429 0.0429
Onchocerca volvulus 0.049 0.1507 0.5306
Brugia malayi STE20-like kinase MST 0.0519 0.1619 0.1614
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0906 0.3158 0.3158
Echinococcus granulosus tyrosine protein kinase otk 0.0281 0.0675 0.067
Schistosoma mansoni hypothetical protein 0.0152 0.0163 0.0158
Echinococcus granulosus dual specificity 0.028 0.0672 0.0667
Schistosoma mansoni notch 0.0266 0.0614 0.0609
Schistosoma mansoni atypical protein kinase C 0.0589 0.19 0.1895
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0439 0.1304 0.1304
Brugia malayi serine/threonine-protein kinase 6 0.0237 0.0501 0.0496
Echinococcus multilocularis casein kinase I gamma 0.043 0.1269 0.1264
Entamoeba histolytica protein kinase, putative 0.0133 0.0086 0.0384
Brugia malayi Protein kinase domain containing protein 0.0331 0.0874 0.0869
Echinococcus granulosus contactin 0.0299 0.0748 0.0743
Plasmodium falciparum thioredoxin reductase 0.2629 1 1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0355 0.0968 0.0968
Schistosoma mansoni rap gtpase-activating protein 0.0226 0.0457 0.0452
Echinococcus multilocularis protein jagged 1 0.0266 0.0614 0.0609
Giardia lamblia High cysteine protein 0.0266 0.0614 0.1342
Entamoeba histolytica disulphide oxidoreductase, putative 0.0242 0.0519 0.2444
Schistosoma mansoni protein kinase 0.0446 0.1331 0.1326
Echinococcus multilocularis neuroglian 0.0638 0.2095 0.2091
Brugia malayi protein kinase C3,putative 0.0318 0.0822 0.0818
Trypanosoma cruzi casein kinase II, putative 0.0202 0.036 0.028
Brugia malayi Protein kinase domain containing protein 0.0906 0.3158 0.3155
Trypanosoma cruzi casein kinase, putative 0.0219 0.0429 0.035
Schistosoma mansoni protein kinase 0.0173 0.0247 0.0242
Entamoeba histolytica protein kinase, putative 0.0246 0.0538 0.2531
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0169 0.0228 0.0148
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0242 0.0519 0.0515
Schistosoma mansoni notch 0.0266 0.0614 0.0609
Echinococcus multilocularis calcium dependent protein kinase 0.0137 0.0104 0.0099
Onchocerca volvulus 0.0657 0.2167 0.763
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0226 0.0457 0.0452
Loa Loa (eye worm) thyroid receptor interactor 0.0207 0.038 0.038
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0228 0.0502
Echinococcus multilocularis neurogenic locus notch protein 4 0.0266 0.0614 0.0609
Trichomonas vaginalis CMGC family protein kinase 0.0239 0.051 0.1409
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0152 0.0163 0.0158
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0228 0.0464 0.0385
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0242 0.0519 0.0441
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0299 0.0748 0.0748
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0173 0.0247 0.0242
Echinococcus multilocularis c src tyrosine kinase 0.019 0.0314 0.0309
Schistosoma mansoni hypothetical protein 0.0152 0.0163 0.0158
Trichomonas vaginalis AGC family protein kinase 0.0164 0.021 0.0444
Plasmodium vivax apical sushi protein, putative 0.049 0.1507 0.1328
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0169 0.0228 0.0148
Schistosoma mansoni growth factor receptor-bound protein 0.0124 0.0052 0.0047
Echinococcus granulosus slit 2 protein 0.031 0.0792 0.0788
Plasmodium vivax protein kinase Crk2 0.0239 0.051 0.031
Echinococcus granulosus protein kinase 0.0309 0.0786 0.0781
Echinococcus multilocularis casein kinase I delta 0.0219 0.0429 0.0424
Schistosoma mansoni glutamate synthase 0.0242 0.0519 0.0515
Onchocerca volvulus 0.0129 0.0071 0.0251
Loa Loa (eye worm) hypothetical protein 0.0528 0.1656 0.1656
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.017 0.0236 0.0155
Plasmodium falciparum cGMP-dependent protein kinase 0.017 0.0233 0.0152
Echinococcus granulosus calcium activated potassium channel 0.0272 0.0639 0.0634
Trypanosoma cruzi casein kinase, putative 0.0219 0.0429 0.035
Echinococcus granulosus epidermal growth factor receptor 0.0489 0.1502 0.1497
Echinococcus granulosus Immunoglobulin 0.0152 0.0163 0.0158
Echinococcus granulosus c src tyrosine kinase 0.019 0.0314 0.0309
Toxoplasma gondii aurora kinase 0.0237 0.0501 0.0422
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.051 0.0505
Brugia malayi Casein kinase II, alpha chain 0.0202 0.036 0.0355
Onchocerca volvulus 0.049 0.1507 0.5306
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0228 0.0464 0.0385
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0462 0.1396 0.1391
Echinococcus granulosus tyrosine protein kinase ABL1 0.0133 0.0086 0.0081
Entamoeba histolytica serine/threonine protein kinase, putative 0.0546 0.1727 0.818
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0173 0.0247 0.0242
Schistosoma mansoni cell adhesion molecule 0.0152 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0228 0.0464 0.0464
Schistosoma mansoni serine/threonine protein kinase 0.0534 0.1678 0.1674
Brugia malayi Immunoglobulin I-set domain containing protein 0.0299 0.0748 0.0743
Schistosoma mansoni serine/threonine protein kinase 0.0495 0.1525 0.152
Schistosoma mansoni cell adhesion molecule 0.0299 0.0748 0.0743
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0911 0.3177 0.2803
Toxoplasma gondii AGC kinase 0.0228 0.0464 0.0385
Schistosoma mansoni notch 0.0266 0.0614 0.0609
Echinococcus multilocularis epidermal growth factor receptor 0.0702 0.2346 0.2342
Schistosoma mansoni protein kinase 0.0309 0.0786 0.0781
Trypanosoma brucei cdc2-related kinase 1 0.0239 0.051 0.0432
Schistosoma mansoni tyrosine kinase 0.0129 0.0072 0.0067
Schistosoma mansoni tyrosine kinase 0.0489 0.1502 0.1497
Echinococcus multilocularis cGMP dependent protein kinase 1 0.017 0.0233 0.0228
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Entamoeba histolytica protein kinase, putative 0.0237 0.0501 0.2355
Echinococcus multilocularis dual specificity 0.028 0.0672 0.0667
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Leishmania major protein kinase A catalytic subunit 0.0228 0.0464 0.0385
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0669 0.2217 0.2213
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Brugia malayi protein unc-22 0.0213 0.0406 0.0401
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Echinococcus granulosus CDC7 cell division cycle 7 0.0181 0.0277 0.0272
Entamoeba histolytica PH domain containing protein kinase, putative 0.0331 0.0875 0.4132
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0129 0.0071 0.0066
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Echinococcus granulosus hypothetical protein 0.0244 0.0528 0.0524
Onchocerca volvulus 0.049 0.1507 0.5306
Schistosoma mansoni vam6/vps39 related 0.0226 0.0457 0.0452
Trichomonas vaginalis STE family protein kinase 0.0173 0.0247 0.0561
Trichomonas vaginalis mercuric reductase, putative 0.0911 0.3177 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0911 0.3177 0.3121
Echinococcus multilocularis serine:threonine protein kinase N2 0.0587 0.189 0.1886
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.1727 0.5328
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0228 0.0502
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Loa Loa (eye worm) AGC/AKT protein kinase 0.059 0.1903 0.1903
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0546 0.1727 0.1722
Onchocerca volvulus Peroxidasin homolog 0.0129 0.0071 0.0251
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Loa Loa (eye worm) AGC/PKG protein kinase 0.017 0.0233 0.0233
Brugia malayi pregnancy-associated plasma protein-A 0.049 0.1507 0.1503
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Toxoplasma gondii NADPH-glutathione reductase 0.0911 0.3177 0.3121
Echinococcus granulosus protein jagged 1 0.0266 0.0614 0.0609
Brugia malayi Fes/CIP4 homology domain containing protein 0.0207 0.038 0.0375
Onchocerca volvulus 0.0129 0.0073 0.0258
Echinococcus multilocularis neurogenic locus protein delta 0.0266 0.0614 0.0609
Echinococcus granulosus serine:threonine protein kinase 3 0.0519 0.1619 0.1614
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0124 0.0052 0.0052
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0228 0.0464 0.0459
Echinococcus multilocularis hypothetical protein 0.0206 0.0377 0.0372
Schistosoma mansoni tyrosine kinase 0.019 0.0314 0.0309
Echinococcus granulosus roundabout 2 0.0809 0.2772 0.2768
Echinococcus multilocularis titin 0.0129 0.0071 0.0066
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0299 0.0748 0.0743
Schistosoma mansoni protein kinase 0.0877 0.3041 0.3037
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0741 0.2502 0.2502
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0129 0.0073 0.0068
Schistosoma mansoni nck2/grb4 0.0124 0.0052 0.0047
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0712 0.2388 0.2384
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0144 0.0144
Giardia lamblia Kinase, CMGC DYRK 0.028 0.0672 0.1539
Trichomonas vaginalis CAMK family protein kinase 0.0203 0.0366 0.0945
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0239 0.051 0.051
Brugia malayi Protein kinase domain containing protein 0.0124 0.0053 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0147 0.0144 0.0144
Schistosoma mansoni sulfide quinone reductase 0.0242 0.0519 0.0515
Giardia lamblia Kinase, CMGC SRPK 0.0167 0.0223 0.0023
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0242 0.0519 0.2444
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0256 0.0575 0.057
Loa Loa (eye worm) hypothetical protein 0.0152 0.0163 0.0163
Echinococcus granulosus tyrosine protein kinase Fyn 0.0309 0.0787 0.0782
Onchocerca volvulus 0.0133 0.0086 0.0301
Schistosoma mansoni tyrosine kinase 0.0702 0.2346 0.2342
Giardia lamblia Kinase, CDC7 0.0181 0.0277 0.0204
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Brugia malayi Cadherin domain containing protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0112 0.0005 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0515 0.1604 0.16
Entamoeba histolytica casein kinase, putative 0.0202 0.036 0.1686
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Echinococcus granulosus tyrosine protein kinase Src42A 0.0309 0.0787 0.0782
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0242 0.0519 0.0441
Loa Loa (eye worm) hypothetical protein 0.0152 0.0163 0.0163
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0242 0.0519 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Entamoeba histolytica protein kinase, putative 0.059 0.1903 0.9018
Echinococcus granulosus basement membrane specific heparan sulfate 0.0152 0.0163 0.0158
Schistosoma mansoni tyrosine kinase 0.0309 0.0787 0.0782
Leishmania major protein kinase, putative 0.0203 0.0366 0.0286
Plasmodium falciparum casein kinase 2, alpha subunit 0.0202 0.036 0.028
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0672 0.1931
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0389 0.1105 0.1105
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0436 0.1291 0.1286
Brugia malayi Protein kinase domain containing protein 0.043 0.1269 0.1264
Trichomonas vaginalis CAMK family protein kinase 0.0255 0.0571 0.1605
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.028 0.0672 0.0595
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.021 0.0205
Echinococcus granulosus protein kinase shaggy 0.0259 0.0589 0.0585
Loa Loa (eye worm) protein kinase domain-containing protein 0.043 0.1269 0.1269
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0144 0.0139
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Schistosoma mansoni tyrosine kinase 0.0423 0.1241 0.1236
Loa Loa (eye worm) programmed cell death 8 0.0242 0.0519 0.0519
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.1727 0.5328
Echinococcus multilocularis insulin growth factor binding 0.0129 0.0071 0.0066
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0232 0.048 0.0475
Onchocerca volvulus 0.049 0.1507 0.5306
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0712 0.2388 0.2388
Giardia lamblia Thioredoxin reductase 0.0242 0.0519 0.1023
Loa Loa (eye worm) hypothetical protein 0.0133 0.0086 0.0086
Echinococcus granulosus casein kinase I delta 0.0219 0.0429 0.0424
Plasmodium falciparum glutathione reductase 0.2629 1 1
Brugia malayi Protein kinase domain containing protein 0.0284 0.0688 0.0683
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0468 0.142 0.142
Echinococcus granulosus protein jagged 1 0.0266 0.0614 0.0609
Schistosoma mansoni titin 0.0281 0.0675 0.067
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.03 0.0295
Loa Loa (eye worm) hypothetical protein 0.0245 0.0532 0.0532
Brugia malayi Variant SH3 domain containing protein 0.0151 0.016 0.0155
Echinococcus multilocularis rho associated protein kinase 0.0657 0.2167 0.2163
Echinococcus multilocularis activin receptor type 0.0132 0.0082 0.0077
Brugia malayi Prion-like- 0.0281 0.0675 0.067
Echinococcus multilocularis cGMP dependent protein kinase 1 0.017 0.0233 0.0228
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.025 0.025
Echinococcus granulosus titin 0.0213 0.0406 0.0401
Loa Loa (eye worm) hypothetical protein 0.0213 0.0404 0.0404
Echinococcus multilocularis protein jagged 2 0.0266 0.0614 0.0609
Echinococcus granulosus activin receptor type 0.0132 0.0082 0.0077
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0169 0.0228 0.0148
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0501 0.1379
Giardia lamblia Kinase, NEK 0.0274 0.0649 0.1462
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0575 0.057
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0167 0.0223 0.0143
Echinococcus multilocularis casein kinase I alpha 0.0219 0.0429 0.0424
Loa Loa (eye worm) hypothetical protein 0.0181 0.0276 0.0276
Schistosoma mansoni peroxidasin 0.0152 0.0165 0.016
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0124 0.0052 0.0052
Onchocerca volvulus 0.0219 0.0429 0.1509
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0167 0.0223 0.0143
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0242 0.0519 0.0515
Loa Loa (eye worm) hypothetical protein 0.0645 0.2121 0.2121
Echinococcus granulosus C type lectin domian containing protein 0.049 0.1507 0.1503
Schistosoma mansoni nephrin 0.0657 0.2168 0.2164
Giardia lamblia Kinase, CMGC CDK 0.0239 0.051 0.0992
Echinococcus granulosus tyrosine kinase 0.0133 0.0086 0.0081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0164 0.021 0.0205
Echinococcus granulosus hemicentin 1 0.0281 0.0675 0.067
Echinococcus granulosus Immunoglobulin 0.051 0.1583 0.1579
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Brugia malayi Cadherin domain containing protein 0.0266 0.0614 0.0609
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0166 0.0217 0.001
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.031 0.079 0.0714
Echinococcus granulosus neuroglian 0.0299 0.0748 0.0743
Schistosoma mansoni neuroglian 0.0299 0.0748 0.0743
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0309 0.0787 0.0782
Brugia malayi Protein kinase domain containing protein 0.0391 0.1112 0.1107
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Brugia malayi Protein kinase domain containing protein 0.0346 0.0932 0.0927
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0203 0.0366 0.0361
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0151 0.016 0.0155
Echinococcus granulosus Vam6:Vps39 protein 0.0226 0.0457 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.043 0.1269 0.1264
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0144 0.0144
Echinococcus granulosus NDR protein kinase 0.0325 0.0849 0.0844
Schistosoma mansoni cell adhesion molecule 0.0147 0.0144 0.0139
Onchocerca volvulus Putative titin 0.0129 0.0071 0.0251
Echinococcus granulosus tyrosine kinase 0.0252 0.0559 0.0554
Echinococcus granulosus dual specificity protein kinase clk2 0.031 0.079 0.0785
Brugia malayi Protein kinase domain containing protein 0.0133 0.0086 0.0081
Brugia malayi casein kinase I 0.0219 0.0429 0.0424
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Schistosoma mansoni glutamate synthase 0.0242 0.0519 0.0515
Schistosoma mansoni kinase 0.0583 0.1875 0.1871
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0219 0.0429 0.0429
Onchocerca volvulus 0.049 0.1507 0.5306
Schistosoma mansoni basigin related 0.0152 0.0163 0.0158
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0242 0.0519 0.0515
Schistosoma mansoni hypothetical protein 0.0152 0.0163 0.0158
Entamoeba histolytica hypothetical protein 0.0246 0.0538 0.2531
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0741 0.2502 0.2498
Loa Loa (eye worm) casein kinase 0.0365 0.1007 0.1007
Schistosoma mansoni cell adhesion molecule 0.0152 0.0163 0.0158
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0321 0.0834 0.0758
Toxoplasma gondii rhoptry neck protein RON1 0.049 0.1507 0.1437
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0129 0.0071 0.0066
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2629 1 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0309 0.0787 0.0782
Leishmania major casein kinase II, putative 0.0202 0.036 0.028
Brugia malayi Hr1 repeat family protein 0.0587 0.189 0.1886
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0999 0.3527 0.3523
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0173 0.0247 0.0242
Leishmania major hypothetical protein, conserved 0.0242 0.0519 0.0441
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0259 0.0589 0.0512
Echinococcus multilocularis mitogen activated protein kinase 11 0.0321 0.0834 0.0829
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0672 0.1931
Brugia malayi hypothetical protein 0.0448 0.1341 0.1336
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.1727 0.1722
Loa Loa (eye worm) hypothetical protein 0.0147 0.0144 0.0144
Brugia malayi Protein kinase domain containing protein 0.0133 0.0086 0.0081
Loa Loa (eye worm) hypothetical protein 0.0661 0.2187 0.2187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0226 0.0457 0.0378
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Echinococcus multilocularis lachesin 0.0281 0.0675 0.067
Onchocerca volvulus 0.0259 0.0589 0.2075
Entamoeba histolytica protein kinase, putative 0.0185 0.0294 0.1371
Echinococcus multilocularis nervana 2 0.025 0.0552 0.0548
Giardia lamblia Kinase, CMGC CDK 0.0239 0.051 0.0992
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0239 0.051 0.051
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.1168 0.1164
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.025 0.0552 0.0548
Echinococcus multilocularis serine:threonine protein kinase N2 0.0325 0.0849 0.0844
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0163 0.0158
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0239 0.051 0.0432
Onchocerca volvulus 0.0389 0.1103 0.3883
Leishmania major hypothetical protein, conserved 0.0242 0.0519 0.0441
Brugia malayi Protein kinase domain containing protein 0.0438 0.1299 0.1294
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0346 0.0932 0.0932
Onchocerca volvulus 0.0129 0.0071 0.0251
Echinococcus multilocularis Immunoglobulin 0.0152 0.0163 0.0158
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0151 0.016 0.016
Echinococcus granulosus protein jagged 2 0.0266 0.0614 0.0609
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0256 0.0575 0.057
Brugia malayi Protein kinase domain containing protein 0.0645 0.2121 0.2117
Trichomonas vaginalis AGC family protein kinase 0.059 0.1903 0.5896
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0259 0.0589 0.0585
Brugia malayi basement membrane proteoglycan precursor 0.0152 0.0163 0.0158
Echinococcus multilocularis expressed conserved protein 0.017 0.0233 0.0228
Echinococcus granulosus serine:threonine protein kinase 0.023 0.0472 0.0468
Echinococcus multilocularis tyrosine protein kinase otk 0.0281 0.0675 0.067
Schistosoma mansoni hypothetical protein 0.0129 0.0071 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0672 0.1931
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0242 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0218 0.0427 0.0427
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0675 0.067
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0163 0.0158
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.028 0.0672 0.0667
Schistosoma mansoni septate junction protein 0.0152 0.0163 0.0158
Brugia malayi Protein kinase domain containing protein 0.023 0.0472 0.0468
Onchocerca volvulus 0.0266 0.0614 0.2162
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Echinococcus granulosus dual specificity 0.0246 0.0538 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0436 0.1291 0.1286
Giardia lamblia Kinase, NEK 0.0274 0.0649 0.1462
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0163 0.0207 0.0126
Echinococcus multilocularis calcium activated potassium channel 0.0272 0.0639 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0277 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0464 0.0459
Schistosoma mansoni c4b-binding protein beta chain 0.049 0.1507 0.1503
Leishmania major protein kinase A catalytic subunit isoform 1 0.0228 0.0464 0.0385
Schistosoma mansoni serine/threonine protein kinase 0.031 0.079 0.0785
Trichomonas vaginalis CK1 family protein kinase 0.0219 0.0429 0.1147
Echinococcus granulosus mitogen activated protein kinase 3 0.0169 0.0228 0.0223
Echinococcus granulosus leucine rich repeat containing protein 4 0.0129 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.051 0.1583 0.1583
Toxoplasma gondii AGC kinase 0.0228 0.0464 0.0385
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0169 0.0228 0.0228
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0684 0.2274 0.2274
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0242 0.0519 0.0441
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0409 0.1183 0.1179
Brugia malayi Protein kinase domain containing protein 0.1904 0.7121 0.712
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0144 0.0144
Echinococcus granulosus c4b binding protein beta chain 0.049 0.1507 0.1503
Brugia malayi Variant SH3 domain containing protein 0.0124 0.0052 0.0047
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0129 0.0073 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.0589 0.1665
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0675 0.067
Schistosoma mansoni tyrosine kinase 0.0407 0.1176 0.1171
Entamoeba histolytica cell division protein kinase 2, putative 0.0239 0.051 0.24
Echinococcus granulosus tyrosine protein kinase Fyn 0.0309 0.0787 0.0782
Schistosoma mansoni sulfide quinone reductase 0.0242 0.0519 0.0515
Brugia malayi Muscle positioning protein 4 0.0266 0.0614 0.0609
Brugia malayi Disorganized muscle protein 1 0.0129 0.0071 0.0066
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0367 0.1019 0.1014
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0242 0.0519 0.0441
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Echinococcus granulosus casein kinase I alpha 0.0219 0.0429 0.0424
Plasmodium falciparum calcium-dependent protein kinase 4 0.0203 0.0366 0.0286
Schistosoma mansoni protein kinase 0.0132 0.0082 0.0077
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0165 0.0213 0.0213
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0292 0.0719 0.0714
Schistosoma mansoni hypothetical protein 0.0242 0.0519 0.0515
Echinococcus granulosus expressed protein 0.0167 0.0223 0.0218
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0226 0.0457 0.0378
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0195 0.0333 0.0328
Echinococcus granulosus low density lipoprotein receptor ldl 0.0152 0.0163 0.0158
Entamoeba histolytica protein kinase domain containing protein 0.0259 0.0589 0.2776
Brugia malayi Protein kinase domain containing protein 0.0712 0.2388 0.2384
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0169 0.0228 0.0148
Onchocerca volvulus Netrin receptor homolog 0.0187 0.0303 0.1068
Schistosoma mansoni protein kinase 0.0741 0.2502 0.2498
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0233 0.0228
Echinococcus multilocularis c4b binding protein beta chain 0.049 0.1507 0.1503
Brugia malayi basement membrane proteoglycan 0.0152 0.0163 0.0158
Brugia malayi Protein kinase domain containing protein 0.0307 0.078 0.0775
Loa Loa (eye worm) glutathione reductase 0.2629 1 1
Schistosoma mansoni protein kinase 0.0219 0.0429 0.0424
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.017 0.0236 0.1096
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0316 0.0814 0.0738
Schistosoma mansoni serine/threonine kinase 0.0446 0.1331 0.1326
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0412 0.1195 0.1195
Onchocerca volvulus 0.0127 0.0065 0.0229
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0911 0.3177 0.3121
Echinococcus granulosus down syndrome cell adhesion 0.0129 0.0071 0.0066
Brugia malayi SH2 domain containing protein 0.0442 0.1316 0.1312
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0203 0.0366 0.0366
Echinococcus multilocularis thioredoxin glutathione reductase 0.2629 1 1
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0501 0.1379
Brugia malayi Calcium binding EGF domain containing protein 0.0266 0.0614 0.0609
Trichomonas vaginalis CAMK family protein kinase 0.0232 0.048 0.1313
Brugia malayi Immunoglobulin I-set domain containing protein 0.0299 0.0748 0.0743
Trypanosoma brucei rac serine-threonine kinase, putative 0.059 0.1903 0.1836
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Schistosoma mansoni protein kinase 0.0535 0.1683 0.1679
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Toxoplasma gondii thioredoxin reductase 0.2629 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0237 0.0501 0.2355
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0164 0.021 0.0205
Plasmodium vivax serine/threonine protein kinase, putative 0.0167 0.0223 0.0017
Echinococcus multilocularis Immunoglobulin subtype 0.0152 0.0163 0.0158
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0163 0.0158
Echinococcus multilocularis casein kinase i 0.0219 0.0429 0.0424
Loa Loa (eye worm) hypothetical protein 0.0242 0.0519 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0165 0.016
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.031 0.079 0.0714
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0633 0.2074 0.2069
Brugia malayi EGF-like domain containing protein 0.0266 0.0614 0.0609
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0242 0.0519 0.1439
Loa Loa (eye worm) hypothetical protein 0.0469 0.1422 0.1422
Onchocerca volvulus 0.049 0.1507 0.5306
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0242 0.0519 0.2444
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0277 0.0658
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.028 0.0672 0.0672
Trichomonas vaginalis AGC family protein kinase 0.0346 0.0932 0.2768
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0228 0.0464 0.0385
Echinococcus multilocularis roundabout 2 0.0299 0.0748 0.0743
Schistosoma mansoni notch 0.0266 0.0614 0.0609
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0331 0.0874 0.0869
Brugia malayi Doublecortin family protein 0.0304 0.0767 0.0763
Echinococcus granulosus roundabout 2 0.0299 0.0748 0.0743
Echinococcus granulosus protein kinase C gamma type 0.0407 0.1178 0.1173
Trypanosoma brucei casein kinase I, isoform 2 0.0219 0.0429 0.035
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0163 0.0207 0.0126
Loa Loa (eye worm) TK/ALK protein kinase 0.0307 0.078 0.078
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.031 0.079 0.0714
Loa Loa (eye worm) TK/ROR protein kinase 0.0195 0.0333 0.0333
Schistosoma mansoni hypothetical protein 0.0129 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.051 0.1583 0.1583
Trypanosoma brucei cdc2-related kinase 3 0.0239 0.051 0.0432
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.189 0.1886
Schistosoma mansoni serine/threonine protein kinase 0.0474 0.1443 0.1439
Echinococcus granulosus raf serine:threonine protein kinase 0.015 0.0156 0.0151
Loa Loa (eye worm) one IG domain family member 0.0129 0.0071 0.0071
Trypanosoma cruzi trypanothione reductase, putative 0.2629 1 1
Schistosoma mansoni hypothetical protein 0.0129 0.0071 0.0066
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0228 0.0464 0.0385
Trypanosoma cruzi NADH dehydrogenase, putative 0.0242 0.0519 0.0441
Plasmodium vivax ferrodoxin reductase, putative 0.0242 0.0519 0.0319
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0259 0.0589 0.0589
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0173 0.0247 0.0242
Giardia lamblia Aurora kinase 0.0237 0.0501 0.096
Brugia malayi Prion-like- 0.0129 0.0071 0.0066
Echinococcus multilocularis neural cadherin 0.0266 0.0614 0.0609
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0144 0.0139
Plasmodium vivax calcium-dependent protein kinase, putative 0.0203 0.0366 0.0163
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0325 0.0849 0.0844
Echinococcus multilocularis cyclin 0.0633 0.2074 0.2069
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.017 0.0233 0.0152
Brugia malayi Protein kinase domain 0.0173 0.0247 0.0242
Loa Loa (eye worm) hypothetical protein 0.0124 0.0052 0.0052
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0309 0.0787 0.0782
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0133 0.0086 0.0384
Plasmodium falciparum ferrodoxin reductase-like protein 0.0242 0.0519 0.0441
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1475 0.5416 0.5414
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0911 0.3177 0.3174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Echinococcus granulosus notch 0.0266 0.0614 0.0609
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0169 0.0228 0.0148
Echinococcus granulosus protein kinase c iota type 0.0577 0.1851 0.1847
Loa Loa (eye worm) TK protein kinase 0.0496 0.1531 0.1531
Onchocerca volvulus 0.0289 0.0706 0.2486
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0672 0.1931
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0256 0.0575 0.057
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0152 0.0163 0.0158
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0149 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0911 0.3177 1
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0242 0.0519 0.0441
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0129 0.0071 0.0066
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0152 0.0163 0.0158
Trypanosoma cruzi casein kinase, putative 0.0219 0.0429 0.035
Brugia malayi Heparan sulfate 0.0152 0.0163 0.0158
Echinococcus multilocularis protein kinase shaggy 0.0259 0.0589 0.0585
Loa Loa (eye worm) gastrulation defective protein 1 0.0805 0.2757 0.2757
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0129 0.0071 0.0071
Schistosoma mansoni titin 0.0129 0.0071 0.0066
Entamoeba histolytica protein kinase, putative 0.059 0.1903 0.9018
Brugia malayi SRC-1 0.0309 0.0787 0.0782
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0675 0.067
Onchocerca volvulus 0.049 0.1507 0.5306
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0266 0.0614 0.0609
Leishmania major protein kinase A catalytic subunit isoform 2 0.0228 0.0464 0.0385
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0266 0.0614 0.0609
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Echinococcus multilocularis tyrosine protein kinase 0.0311 0.0793 0.0788
Schistosoma mansoni serine/threonine-protein kinase 0.0331 0.0875 0.087
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0242 0.0519 0.0515
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0203 0.0366 0.0163
Entamoeba histolytica protein kinase, putative 0.0167 0.0223 0.1037
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0151 0.016 0.0155
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0469 0.1422 0.1417
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0152 0.0163 0.0163
Echinococcus multilocularis hemicentin 1 0.0281 0.0675 0.067
Giardia lamblia Kinase, CMGC MAPK 0.0169 0.0228 0.004
Onchocerca volvulus 0.0266 0.0614 0.2162
Loa Loa (eye worm) TK/FER protein kinase 0.0442 0.1316 0.1316
Trichomonas vaginalis CK1 family protein kinase 0.0219 0.0429 0.1147
Echinococcus granulosus serine:threonine protein kinase N2 0.0587 0.189 0.1886
Brugia malayi Calcium binding EGF domain containing protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0239 0.051 0.051
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.017 0.0236 0.1096
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0304 0.0767 0.0767
Schistosoma mansoni protein kinase 0.0173 0.0247 0.0242
Trypanosoma cruzi cdc2-related kinase 3 0.0239 0.051 0.0432
Trichomonas vaginalis AGC family protein kinase 0.0228 0.0464 0.126
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0325 0.0849 0.0844
Entamoeba histolytica protein kinase, putative 0.0575 0.1842 0.8729
Loa Loa (eye worm) hypothetical protein 0.0181 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0277 0.0272
Plasmodium falciparum serine/threonine protein kinase, putative 0.0237 0.0501 0.0422
Trichomonas vaginalis STE family protein kinase 0.0173 0.0247 0.0561
Schistosoma mansoni protein kinase 0.0877 0.3041 0.3037
Plasmodium vivax unspecified product 0.0202 0.036 0.0157
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0309 0.0787 0.0782
Brugia malayi hypothetical protein 0.0528 0.1656 0.1652
Echinococcus multilocularis tyrosine protein kinase shark 0.0351 0.0952 0.0947
Trypanosoma brucei polo-like protein kinase 0.0546 0.1727 0.1658
Schistosoma mansoni vesicular amine transporter 0.051 0.1583 0.1579
Onchocerca volvulus 0.0226 0.0457 0.1607
Schistosoma mansoni cell adhesion molecule 0.0299 0.0748 0.0743
Leishmania major trypanothione reductase 0.2629 1 1
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0274 0.0649 0.0572
Giardia lamblia Kinase, AGC AKT 0.0236 0.0496 0.0944
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0259 0.0589 0.0585
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Echinococcus granulosus casein kinase I alpha 0.0219 0.0429 0.0424
Echinococcus multilocularis protein tyrosine kinase 0.0583 0.1873 0.1869
Brugia malayi Cam kinase protein 1 0.0203 0.0366 0.0361
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Onchocerca volvulus 0.0281 0.0674 0.2372
Echinococcus granulosus neurogenic locus notch protein 0.0266 0.0614 0.0609
Onchocerca volvulus 0.0266 0.0614 0.2162
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0252 0.0559 0.0554
Leishmania major NADH dehydrogenase, putative 0.0242 0.0519 0.0441
Echinococcus granulosus fibroblast growth factor receptor 4 0.0367 0.1019 0.1014
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0331 0.0874 0.0869
Trypanosoma cruzi cdc2-related kinase 3 0.0239 0.051 0.0432
Echinococcus multilocularis titin 0.0129 0.0071 0.0066
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0292 0.0719 0.0714
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.031 0.079 0.2311
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0203 0.0366 0.0286
Brugia malayi Protein kinase domain containing protein 0.0133 0.0086 0.0081
Echinococcus granulosus tyrosine protein kinase Lyn 0.0375 0.1049 0.1044
Brugia malayi EGF-like domain containing protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) TK/EPH protein kinase 0.0231 0.0476 0.0476
Giardia lamblia Kinase, AGC PKA 0.0316 0.0814 0.2018
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0242 0.0519 0.0441
Echinococcus multilocularis mitogen activated protein kinase 14 0.0321 0.0834 0.0829
Plasmodium falciparum glutathione reductase 0.0911 0.3177 0.3121
Loa Loa (eye worm) AGC/PKA protein kinase 0.0228 0.0464 0.0464
Echinococcus multilocularis titin 0.0213 0.0406 0.0401
Schistosoma mansoni serine/threonine protein kinase 0.0409 0.1183 0.1179
Trichomonas vaginalis STE family protein kinase 0.0274 0.0649 0.1858
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0162 0.0202 0.0197
Echinococcus multilocularis roundabout 2 0.0299 0.0748 0.0743
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0712 0.2388 0.2384
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0316 0.0814 0.0809
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0281 0.0675 0.0675
Giardia lamblia Kinase, STE STE20 0.017 0.0236 0.0065
Loa Loa (eye worm) hypothetical protein 0.049 0.1507 0.1507
Schistosoma mansoni cell adhesion molecule 0.0129 0.0071 0.0066
Echinococcus granulosus delta-like protein 1 0.0266 0.0614 0.0609
Echinococcus multilocularis neurogenic locus notch protein 0.0266 0.0614 0.0609
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Echinococcus granulosus tyrosine protein kinase Fyn 0.0309 0.0787 0.0782
Echinococcus multilocularis cyclin dependent kinase 1 0.0239 0.051 0.0505
Echinococcus granulosus cyclin dependent kinase 5 0.0239 0.051 0.0505
Onchocerca volvulus 0.049 0.1507 0.5306
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Echinococcus granulosus Immunoglobulin subtype 0.0152 0.0163 0.0158
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0633 0.2074 0.2069
Entamoeba histolytica thioredoxin reductase, putative 0.0242 0.0519 0.2444
Giardia lamblia Kinase, AGC PKA 0.0228 0.0464 0.0835
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.017 0.0236 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0429 0.0424
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0645 0.2121 0.2121
Onchocerca volvulus 0.0133 0.0086 0.0301
Brugia malayi phosphoinositide-dependent protein kinase I 0.0164 0.021 0.0205
Leishmania major protein kinase, putative 0.0237 0.0501 0.0422
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0446 0.1331 0.1326
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0242 0.0519 0.0441
Brugia malayi putative serine/threonine kinase SADA gamma 0.0157 0.0184 0.0179
Trichomonas vaginalis STE family protein kinase 0.0173 0.0247 0.0561
Brugia malayi Protein kinase domain containing protein 0.0246 0.0538 0.0533
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0712 0.2388 0.2388
Onchocerca volvulus 0.0133 0.0086 0.0301
Trichomonas vaginalis STE family protein kinase 0.017 0.0236 0.0526
Trypanosoma brucei aurora B kinase 0.0237 0.0501 0.0422
Schistosoma mansoni nephrin 0.0299 0.0748 0.0743
Schistosoma mansoni netrin receptor unc5 0.0152 0.0163 0.0158
Brugia malayi EGF-like domain containing protein 0.0266 0.0614 0.0609
Schistosoma mansoni serine/threonine protein kinase 0.031 0.079 0.0785
Loa Loa (eye worm) TK protein kinase 0.0252 0.0559 0.0559
Entamoeba histolytica protein kinase domain containing protein 0.0202 0.036 0.1686
Schistosoma mansoni ephrin receptor 0.0195 0.0335 0.033
Echinococcus multilocularis fibropellin Ia 0.0266 0.0614 0.0609
Brugia malayi Myb-like DNA-binding domain containing protein 0.0129 0.0071 0.0066
Echinococcus multilocularis 0.0129 0.0071 0.0066
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0157 0.0184 0.0103
Brugia malayi Sushi domain 0.049 0.1507 0.1503
Entamoeba histolytica protein kinase domain containing protein 0.028 0.0672 0.3169
Echinococcus granulosus neurogenic locus protein delta 0.0266 0.0614 0.0609
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.031 0.079 0.0714
Echinococcus multilocularis CDC7 cell division cycle 7 0.0181 0.0277 0.0272
Echinococcus granulosus neurogenic locus notch protein 0.0266 0.0614 0.0609
Onchocerca volvulus Putative cubilin 0.0266 0.0614 0.2162
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0152 0.0163 0.0158
Echinococcus multilocularis dual specificity 0.0246 0.0538 0.0533
Echinococcus granulosus neurogenic locus notch protein 4 0.0266 0.0614 0.0609
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0203 0.0366 0.0286
Loa Loa (eye worm) hypothetical protein 0.0528 0.1656 0.1656
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0645 0.2121 0.2121
Echinococcus granulosus neural cadherin 0.0266 0.0614 0.0609
Echinococcus multilocularis Glutaredoxin protein 5 0.025 0.0552 0.0548
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0911 0.3177 0.3174
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0184 0.0179
Giardia lamblia Kinase, CMGC GSK 0.0259 0.0589 0.1259
Echinococcus granulosus casein kinase I delta 0.0219 0.0429 0.0424
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0242 0.0519 0.2444
Entamoeba histolytica protein kinase, putative 0.0145 0.0133 0.061
Loa Loa (eye worm) hypothetical protein 0.0281 0.0675 0.0675
Loa Loa (eye worm) hypothetical protein 0.079 0.2699 0.2699
Echinococcus multilocularis tyrosine protein kinase Srms 0.0252 0.0559 0.0554
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0242 0.0519 0.0441
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0242 0.0519 0.0515
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0169 0.0228 0.0148
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0281 0.0675 0.067
Entamoeba histolytica protein kinase , putative 0.0237 0.0501 0.2355
Brugia malayi Immunoglobulin I-set domain containing protein 0.021 0.0395 0.039
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0911 0.3177 0.3033
Echinococcus multilocularis cyclin dependent kinase 9 0.012 0.0037 0.0032
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0163 0.0158
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0281 0.0675 0.0675
Trypanosoma cruzi hypothetical protein, conserved 0.0242 0.0519 0.0441
Echinococcus multilocularis raf serine:threonine protein kinase 0.015 0.0156 0.0151
Brugia malayi Protein kinase domain containing protein 0.059 0.1903 0.1899
Plasmodium vivax glycogen synthase kinase 3, putative 0.0259 0.0589 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1514 0.1509
Brugia malayi Protein kinase domain containing protein 0.0389 0.1105 0.11
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0741 0.2502 0.2498
Loa Loa (eye worm) TK/ABL protein kinase 0.0133 0.0086 0.0086
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0242 0.0519 0.0441
Echinococcus granulosus lachesin 0.0281 0.0675 0.067
Plasmodium vivax glutathione reductase, putative 0.2629 1 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0309 0.0787 0.0782
Echinococcus multilocularis insulin receptor 0.0607 0.1972 0.1968
Echinococcus multilocularis protein jagged 1 0.0266 0.0614 0.0609
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0796 0.2722 0.2722
Brugia malayi P38 map kinase family protein 2 0.0321 0.0834 0.0829
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0133 0.0086 0.0382
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0911 0.3177 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0911 0.3177 0.3121
Plasmodium falciparum casein kinase 1 0.0219 0.0429 0.035
Schistosoma mansoni tyrosine kinase 0.0423 0.1241 0.1236
Loa Loa (eye worm) LAD-2 short isoform 0.0152 0.0163 0.0163
Echinococcus granulosus serine:threonine protein kinase N2 0.0262 0.06 0.0596
Echinococcus granulosus epidermal growth factor receptor 0.0702 0.2346 0.2342
Schistosoma mansoni hypothetical protein 0.0129 0.0071 0.0066
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036
Giardia lamblia NADH oxidase lateral transfer candidate 0.0911 0.3177 1
Brugia malayi Serine/threonine-protein kinase SULU 0.0448 0.1341 0.1336
Schistosoma mansoni nephrin related 0.0129 0.0071 0.0066
Trypanosoma brucei hypothetical protein, conserved 0.0242 0.0519 0.0441
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0236 0.0496 0.0491
Loa Loa (eye worm) hypothetical protein 0.0226 0.0457 0.0457
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0309 0.0787 0.0782
Onchocerca volvulus 0.0242 0.0519 0.1829
Loa Loa (eye worm) hypothetical protein 0.0933 0.3265 0.3265
Brugia malayi EGF-like domain containing protein 0.0266 0.0614 0.0609
Onchocerca volvulus 0.0133 0.0086 0.0301
Echinococcus multilocularis 0.0195 0.0332 0.0327
Giardia lamblia Kinase, PLK 0.0546 0.1727 0.5101
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Echinococcus multilocularis C type lectin domian containing protein 0.049 0.1507 0.1503
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0256 0.0575 0.0575
Brugia malayi Fibronectin type III domain containing protein 0.0528 0.1656 0.1652
Schistosoma mansoni adapter molecule crk 0.0124 0.0052 0.0047
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0626 0.2045 0.2041
Schistosoma mansoni tyrosine kinase 0.0607 0.1972 0.1968
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0228 0.0464 0.0459
Echinococcus granulosus insulin receptor 0.0607 0.1972 0.1968
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0203 0.0366 0.0366
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0239 0.051 0.0505
Loa Loa (eye worm) hypothetical protein 0.0281 0.0674 0.0674
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0242 0.0519 0.1023
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0877 0.3041 0.3037
Entamoeba histolytica protein kinase, putative 0.028 0.0672 0.3169
Echinococcus granulosus serine/threonine protein kinase 0.0331 0.0875 0.087
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0151 0.016 0.0155
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0911 0.3177 0.3121
Loa Loa (eye worm) hypothetical protein 0.0373 0.1042 0.1042
Echinococcus multilocularis cyclin dependent kinase 5 0.0239 0.051 0.0505
Brugia malayi Furin-like cysteine rich region family protein 0.0702 0.2346 0.2342
Echinococcus granulosus glutamate synthase 0.0242 0.0519 0.0515
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0281 0.0675 0.0675
Echinococcus multilocularis fat cadherin tumor suppressor 0.0266 0.0614 0.0609
Loa Loa (eye worm) hypothetical protein 0.0389 0.1103 0.1103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0144 0.0139
Schistosoma mansoni tyrosine kinase 0.019 0.0314 0.0309
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0448 0.1341 0.1336
Brugia malayi Immunoglobulin I-set domain containing protein 0.0213 0.0406 0.0401
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0203 0.0366 0.0286
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.049 0.1507 0.1507
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0129 0.0071 0.0066
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.028 0.0672 0.0595
Loa Loa (eye worm) TK/INSR protein kinase 0.0607 0.1972 0.1972
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0152 0.0163 0.0158
Onchocerca volvulus 0.0631 0.2067 0.7277
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Toxoplasma gondii selenide, water dikinase 0.0242 0.0519 0.0441
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0228 0.0502
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0911 0.3177 0.3121
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.036 0.0926
Brugia malayi Protein kinase domain containing protein 0.0325 0.0849 0.0844
Brugia malayi Protein kinase domain containing protein 0.0239 0.051 0.0505
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0157 0.0184 0.0103
Giardia lamblia Kinase, CMGC CK2 0.0202 0.036 0.0484
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0464 0.0459
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0316 0.0814 0.0809
Echinococcus multilocularis rac serine:threonine kinase 0.0331 0.0875 0.087
Trypanosoma cruzi cdc2-related kinase 1 0.0239 0.051 0.0432
Plasmodium falciparum serine/threonine protein kinase 0.0167 0.0223 0.0143
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0251 0.0557 0.0479
Onchocerca volvulus 0.0213 0.0406 0.1429
Trichomonas vaginalis AGC family protein kinase 0.0361 0.0993 0.2964
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0156 0.0151
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0405 0.1168 0.1168
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0911 0.3177 0.2803
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0439 0.1304 0.1299
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0237 0.0501 0.2355
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.033 0.0871 0.0871
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Echinococcus granulosus cyclin dependent kinase 0.0239 0.051 0.0505
Trichomonas vaginalis STE family protein kinase 0.0173 0.0247 0.0561
Plasmodium falciparum calcium-dependent protein kinase 2 0.0203 0.0366 0.0286
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Brugia malayi Temporarily assigned gene name protein 59 0.0261 0.0595 0.059
Echinococcus granulosus tyrosine protein kinase 0.0311 0.0793 0.0788
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0911 0.3177 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0152 0.0163 0.0158
Loa Loa (eye worm) hypothetical protein 0.0365 0.101 0.101
Echinococcus multilocularis dual specificity 0.028 0.0672 0.0667
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0242 0.0519 0.0515
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.017 0.0236 0.0236
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0911 0.3177 1
Onchocerca volvulus 0.0129 0.0071 0.0251
Loa Loa (eye worm) TK protein kinase 0.0185 0.0294 0.0294
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0242 0.0519 0.0441
Onchocerca volvulus 0.0133 0.0086 0.0301
Trypanosoma brucei protein kinase, putative 0.0259 0.0589 0.0512
Brugia malayi Protein kinase c protein 2 0.0233 0.0485 0.048
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0203 0.0366 0.0361
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0242 0.0519 0.0441
Echinococcus multilocularis mitogen activated protein kinase 3 0.0169 0.0228 0.0223
Schistosoma mansoni protein kinase 0.0202 0.036 0.0355
Echinococcus multilocularis 0.0309 0.0786 0.0781
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0167 0.0223 0.0223
Echinococcus granulosus casein kinase I alpha 0.0219 0.0429 0.0424
Brugia malayi Protein kinase domain containing protein 0.0405 0.1168 0.1164
Loa Loa (eye worm) TK/FER protein kinase 0.0133 0.0086 0.0086
Echinococcus granulosus mitogen activated protein kinase 11 0.0321 0.0834 0.0829
Entamoeba histolytica protein kinase, putative 0.0164 0.021 0.0975
Schistosoma mansoni protein kinase 0.0237 0.0501 0.0496
Loa Loa (eye worm) notch protein 0.0266 0.0614 0.0614
Echinococcus multilocularis Immunoglobulin 0.0152 0.0163 0.0158
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0409 0.1183 0.1183
Echinococcus granulosus roundabout 2 0.0299 0.0748 0.0743
Trichomonas vaginalis AGC family protein kinase 0.0172 0.0243 0.0548
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1904 0.7121 0.7121
Brugia malayi Immunoglobulin I-set domain containing protein 0.0129 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.0281 0.0675 0.0675
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0242 0.0519 0.0441
Plasmodium vivax casein kinase 1, putative 0.0219 0.0429 0.0227
Brugia malayi EGF-like domain containing protein 0.0266 0.0614 0.0609
Schistosoma mansoni tyrosine kinase 0.0284 0.0686 0.0682
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.019 0.0314 0.0309
Plasmodium falciparum calcium-dependent protein kinase 3 0.0203 0.0366 0.0286
Loa Loa (eye worm) hypothetical protein 0.0756 0.2562 0.2562
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Onchocerca volvulus 0.0181 0.0277 0.0975
Echinococcus multilocularis titin 0.0129 0.0071 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0911 0.3177 0.3121
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.017 0.0236 0.0155
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0911 0.3177 0.3121
Schistosoma mansoni cell adhesion molecule 0.0281 0.0675 0.067
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0309 0.0787 0.0782
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0495 0.1525 0.152
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0228 0.0464 0.0385
Brugia malayi Stress-activated protein kinase jnk-1 0.0534 0.1678 0.1674
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0299 0.0748 0.0743
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0266 0.0614 0.2162
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0228 0.0464 0.0385
Brugia malayi Immunoglobulin domain containing protein 0.0152 0.0163 0.0158
Schistosoma mansoni growth factor receptor-bound protein 0.0126 0.006 0.0055
Echinococcus granulosus casein kinase I gamma 0.043 0.1269 0.1264
Entamoeba histolytica casein kinase 1, putative 0.0219 0.0429 0.2012
Loa Loa (eye worm) AUR protein kinase 0.0237 0.0501 0.0501
Loa Loa (eye worm) TK/EGFR protein kinase 0.0702 0.2346 0.2346
Echinococcus multilocularis tyrosine kinase 0.0133 0.0086 0.0081
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0274 0.0649 0.0452
Loa Loa (eye worm) hypothetical protein 0.0129 0.0071 0.0071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.0675 0.067
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0129 0.0071 0.0066
Schistosoma mansoni hypothetical protein 0.0266 0.0614 0.0609
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0495 0.1525 0.1525
Echinococcus granulosus Down syndrome cell adhesion molecule 0.017 0.0236 0.0231
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0911 0.3177 0.3174
Brugia malayi hypothetical protein 0.049 0.1507 0.1503
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1359 0.4956 0.4956
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.031 0.079 0.0714
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0501 0.1379
Echinococcus multilocularis cyclin dependent kinase 1 0.0239 0.051 0.0505
Trypanosoma cruzi casein kinase, putative 0.0219 0.0429 0.035
Schistosoma mansoni hemicentin 0.0147 0.0144 0.0139
Brugia malayi serine/threonine kinase 12 0.0237 0.0501 0.0496
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0672 0.1931
Echinococcus multilocularis tyrosine protein kinase HCK 0.0185 0.0294 0.0289
Echinococcus multilocularis N chimaerin 0.0151 0.016 0.0155
Schistosoma mansoni hypothetical protein 0.0152 0.0163 0.0158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0299 0.0748 0.0748
Trypanosoma cruzi NADH dehydrogenase, putative 0.0242 0.0519 0.0441
Echinococcus multilocularis protein kinase c iota type 0.0577 0.1851 0.1847
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0151 0.016 0.0155
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0157 0.0184 0.0103
Schistosoma mansoni g1/s-specific cyclin C 0.1268 0.4598 0.4595
Trypanosoma cruzi polo-like protein kinase, putative 0.0546 0.1727 0.1658
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0239 0.051 0.0432
Echinococcus multilocularis growth factor receptor bound protein 2 0.0124 0.0052 0.0047
Echinococcus multilocularis netrin receptor unc 5 0.021 0.0395 0.039
Echinococcus granulosus insulin growth factor binding 0.0129 0.0071 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0239 0.051 0.1409
Schistosoma mansoni tyrosine kinase 0.0347 0.0936 0.0931
Entamoeba histolytica hypothetical protein 0.0388 0.1101 0.5206
Trichomonas vaginalis AGC family protein kinase 0.0346 0.0932 0.2768
Schistosoma mansoni serine/threonine kinase 0.0325 0.0849 0.0844
Echinococcus granulosus cyclin dependent kinase 19 0.0871 0.3018 0.3015
Echinococcus granulosus NCK adaptor protein 0.0124 0.0052 0.0047
Loa Loa (eye worm) hypothetical protein 0.0244 0.0528 0.0528
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0316 0.0814 0.0738
Schistosoma mansoni titin 0.0129 0.0071 0.0066
Loa Loa (eye worm) hypothetical protein 0.031 0.0792 0.0792
Entamoeba histolytica protein kinase, putative 0.0203 0.0366 0.1714
Loa Loa (eye worm) hypothetical protein 0.0174 0.0249 0.0249
Echinococcus multilocularis nervana 2 0.025 0.0552 0.0548
Schistosoma mansoni serine/threonine protein kinase 0.0474 0.1443 0.1439
Schistosoma mansoni basigin related 0.0152 0.0163 0.0158
Trypanosoma cruzi trypanothione reductase, putative 0.0911 0.3177 0.3121
Trichomonas vaginalis CAMK family protein kinase 0.0546 0.1727 0.5328
Echinococcus multilocularis transfer RNA-Phe 0.0147 0.0144 0.0139
Echinococcus multilocularis hemicentin 1 0.0281 0.0675 0.067
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0911 0.3177 0.3121
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0242 0.0519 0.2444
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0219 0.0429 0.035
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0246 0.0538 0.046
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0259 0.0589 0.0512
Schistosoma mansoni titin 0.0129 0.0071 0.0066
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0911 0.3177 0.3121
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0534 0.1678 0.1674
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.023 0.0472 0.0472
Brugia malayi Immunoglobulin I-set domain containing protein 0.1359 0.4956 0.4953
Brugia malayi Protein kinase domain containing protein 0.0133 0.0086 0.0081
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0796 0.2722 0.2718
Entamoeba histolytica protein kinase domain containing protein 0.0259 0.0589 0.2776
Schistosoma mansoni laminin gamma-3 chain 0.0266 0.0614 0.0609
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0237 0.0501 0.0496
Entamoeba histolytica protein kinase domain containing protein 0.0132 0.0082 0.0365
Echinococcus granulosus rho-associated protein kinase 1 0.0657 0.2167 0.2163
Plasmodium falciparum calcium-dependent protein kinase 5 0.0203 0.0366 0.0286
Onchocerca volvulus 0.0129 0.0071 0.0251
Brugia malayi Peroxidasin 0.0281 0.0677 0.0672
Brugia malayi MAP kinase sur-1 0.0169 0.0228 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0639 0.0634
Plasmodium falciparum calcium-dependent protein kinase 1 0.0203 0.0366 0.0286
Brugia malayi serine/threonine protein kinase 6 0.0237 0.0501 0.0496
Loa Loa (eye worm) hypothetical protein 0.0266 0.0614 0.0614
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0153 0.0167 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0871 0.3018 0.3015
Echinococcus granulosus tyrosine protein kinase Blk 0.0252 0.0559 0.0554
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0438 0.1299 0.1299
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0442 0.1316 0.1312
Brugia malayi Variant SH3 domain containing protein 0.0124 0.0052 0.0047
Onchocerca volvulus 0.0373 0.1042 0.3669
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0436 0.1291 0.1286
Entamoeba histolytica protein kinase, putative 0.0173 0.0247 0.1148
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0173 0.0247 0.0242
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0242 0.0519 0.0515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.0144 0.0139
Schistosoma mansoni titin 0.0147 0.0144 0.0139
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0299 0.0748 0.0743
Echinococcus multilocularis casein kinase I alpha 0.0219 0.0429 0.0424
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.1341 0.1336
Onchocerca volvulus 0.0129 0.0071 0.0251
Schistosoma mansoni protein kinase 0.0877 0.3041 0.3037
Loa Loa (eye worm) hypothetical protein 0.0129 0.0073 0.0073
Schistosoma mansoni protein kinase 0.0129 0.0073 0.0067
Brugia malayi Egg laying defective protein 4 0.017 0.0233 0.0228
Brugia malayi Sex muscle abnormal protein 5 0.0124 0.0052 0.0047
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0259 0.0589 0.0585
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0228 0.0464 0.0385
Loa Loa (eye worm) hypothetical protein 0.0605 0.1964 0.1964
Trichomonas vaginalis CAMK family protein kinase 0.0157 0.0184 0.036

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 12 nM Inhibition of [125I]-eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cells ChEMBL. 15771462
IC50 (binding) = 12 nM Inhibition of [125I]-eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cells ChEMBL. 15771462
IC50 (binding) = 78 nM Inhibition of [125I]-eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cells ChEMBL. 15771462
Ki (binding) 0 nM Inhibitory constant for 5-hydroxytryptamine 2A receptor (NT= Not tested) ChEMBL. 15771462
Ki (binding) 0 nM Inhibitory constant for 5-hydroxytryptamine 2C receptor (NT= Not tested) ChEMBL. 15771462
Ki (binding) 0 nM Inhibitory constant for Dopamine receptor D2 (NT= Not tested) ChEMBL. 15771462
Ki (binding) = 271 nM Inhibitory constant for Dopamine receptor D2 ChEMBL. 15771462
Ki (binding) = 869 nM Inhibitory constant for 5-hydroxytryptamine 2A receptor ChEMBL. 15771462
Ki (binding) = 2315 nM Inhibitory constant for 5-hydroxytryptamine 2C receptor ChEMBL. 15771462

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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