Detailed information for compound 313150

Basic information

Technical information
  • TDR Targets ID: 313150
  • Name: methyl 2-[[2-[(2R)-2-hexyl-2-methyl-5-oxothio phen-3-yl]oxyacetyl]amino]acetate
  • MW: 343.438 | Formula: C16H25NO5S
  • H donors: 1 H acceptors: 3 LogP: 2.82 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC[C@@]1(C)SC(=O)C=C1OCC(=O)NCC(=O)OC
  • InChi: 1S/C16H25NO5S/c1-4-5-6-7-8-16(2)12(9-15(20)23-16)22-11-13(18)17-10-14(19)21-3/h9H,4-8,10-11H2,1-3H3,(H,17,18)/t16-/m1/s1
  • InChiKey: LOIBXRPPXRGNAR-MRXNPFEDSA-N  

Network

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Synonyms

  • methyl 2-[[2-[[(2R)-2-hexyl-2-methyl-5-oxo-3-thienyl]oxy]acetyl]amino]acetate
  • 2-[[2-[[(2R)-2-hexyl-2-methyl-5-oxo-3-thienyl]oxy]-1-oxoethyl]amino]acetic acid methyl ester
  • methyl 2-[2-[(2R)-2-hexyl-2-methyl-5-oxo-thiophen-3-yl]oxyethanoylamino]ethanoate
  • 2-[[2-[[(2R)-2-hexyl-5-keto-2-methyl-3-thienyl]oxy]acetyl]amino]acetic acid methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0146 0.0359
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.125 0.3237 0.3237
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0332 0.0603 0.0603
Onchocerca volvulus 0.0134 0.0036 0.0054
Echinococcus multilocularis casein kinase I alpha 0.0224 0.0293 0.0293
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0545 0.1216 0.1216
Echinococcus granulosus tyrosine protein kinase Src42A 0.019 0.0197 0.0197
Giardia lamblia Kinase, PLK 0.0558 0.1252 0.36
Echinococcus multilocularis C type lectin domian containing protein 0.0673 0.1581 0.1581
Brugia malayi Protein kinase domain containing protein 0.0651 0.1518 0.1508
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.125 0.3237 0.3212
Onchocerca volvulus 0.0134 0.0036 0.0054
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0635 0.1472 0.1472
Echinococcus granulosus CDC7 cell division cycle 7 0.0185 0.0181 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Echinococcus granulosus low density lipoprotein receptor ldl 0.0199 0.0223 0.0223
Mycobacterium ulcerans flavoprotein disulfide reductase 0.125 0.3237 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Onchocerca volvulus 0.0673 0.1581 0.7255
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.1102 0.1091
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Schistosoma mansoni hypothetical protein 0.0199 0.0223 0.0211
Loa Loa (eye worm) hypothetical protein 0.038 0.074 0.0729
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0134 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Loa Loa (eye worm) hypothetical protein 0.0287 0.0473 0.0462
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Echinococcus granulosus casein kinase I delta 0.0224 0.0293 0.0293
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1252 0.3808
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0728 0.174 0.173
Echinococcus granulosus serine:threonine protein kinase 0.0235 0.0326 0.0326
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0332 0.0602 0.1783
Leishmania major protein kinase, putative 0.0242 0.0344 0.0309
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0332 0.0602 0.0568
Schistosoma mansoni tyrosine kinase 0.0495 0.107 0.106
Brugia malayi RhoGAP domain containing protein 0.0154 0.0092 0.0081
Echinococcus multilocularis tyrosine protein kinase HCK 0.0188 0.0189 0.0189
Echinococcus granulosus activin receptor type 0.0134 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Entamoeba histolytica protein kinase domain containing protein 0.0252 0.0374 0.1887
Schistosoma mansoni serine/threonine protein kinase 0.0234 0.0322 0.0311
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0332 0.0602 0.1783
Loa Loa (eye worm) cyclin domain-containing protein 0.0756 0.1819 0.181
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0233 0.0319 0.0284
Trypanosoma brucei rac serine-threonine kinase, putative 0.0603 0.1381 0.135
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0587 0.1336 0.1326
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.125 0.3237 0.3212
Leishmania major hypothetical protein, conserved 0.0332 0.0602 0.0568
Schistosoma mansoni protein kinase 0.0177 0.0159 0.0148
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.093 0.093
Echinococcus multilocularis tyrosine protein kinase 0.0313 0.0549 0.0549
Echinococcus granulosus slit 2 protein 0.041 0.0827 0.0827
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0446 0.0931 0.0931
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0208 0.0247 0.0247
Brugia malayi Protein kinase domain containing protein 0.0332 0.0603 0.0592
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.026 0.0396 0.0396
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0173 0.0146 0.011
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0168 0.0132 0.0121
Entamoeba histolytica protein kinase, putative 0.0211 0.0255 0.1231
Schistosoma mansoni notch 0.0364 0.0696 0.0685
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Entamoeba histolytica protein kinase, putative 0.0265 0.0412 0.2096
Onchocerca volvulus Peroxidasin homolog 0.0167 0.0129 0.0489
Schistosoma mansoni serine/threonine protein kinase 0.06 0.1372 0.1362
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1252 0.3808
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0208 0.0247 0.0247
Echinococcus granulosus mitogen activated protein kinase 11 0.0328 0.0593 0.0593
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0332 0.0603 0.0603
Echinococcus granulosus protein jagged 1 0.0364 0.0696 0.0696
Onchocerca volvulus 0.0166 0.0128 0.0482
Brugia malayi Cyclin, N-terminal domain containing protein 0.0756 0.1819 0.181
Schistosoma mansoni basigin related 0.0199 0.0223 0.0211
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0255 0.0383 0.0383
Onchocerca volvulus 0.0185 0.0181 0.0733
Loa Loa (eye worm) TK protein kinase 0.0313 0.0549 0.0538
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0167 0.0129 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0145 0.0133
Echinococcus granulosus titin 0.0166 0.0128 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0398 0.1148
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0166 0.0128 0.0116
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0332 0.0602 0.0568
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0208 0.0247 0.0212
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0245 0.0354 0.0319
Schistosoma mansoni protein kinase 0.0757 0.1824 0.1814
Echinococcus multilocularis cyclin dependent kinase 19 0.103 0.2608 0.2608
Echinococcus multilocularis neuroglian 0.0822 0.2011 0.2011
Echinococcus multilocularis notch 0.0364 0.0696 0.0696
Loa Loa (eye worm) TK/ABL protein kinase 0.0134 0.0036 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Echinococcus multilocularis casein kinase ii subunit alpha 0.0206 0.0243 0.0243
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0218 0.0276 0.0265
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0918 0.2285 0.2276
Entamoeba histolytica protein kinase 2, putative 0.0323 0.0578 0.3007
Loa Loa (eye worm) AGC/AKT protein kinase 0.0603 0.1381 0.1371
Loa Loa (eye worm) TK/EPH protein kinase 0.0235 0.0325 0.0314
Onchocerca volvulus 0.0253 0.0375 0.1636
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0332 0.0602 0.3141
Loa Loa (eye worm) disorganized muscle protein 1 0.0166 0.0128 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0181 0.0169
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0473 0.138
Brugia malayi hypothetical protein 0.0231 0.0313 0.0301
Schistosoma mansoni hypothetical protein 0.0199 0.0223 0.0211
Brugia malayi hypothetical protein 0.0675 0.1587 0.1577
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0366 0.07 0.0689
Entamoeba histolytica protein kinase, putative 0.0208 0.0247 0.119
Brugia malayi Protein kinase domain containing protein 0.103 0.2608 0.2599
Brugia malayi protein-tyrosine kinase 0.0255 0.0383 0.0371
Schistosoma mansoni protein kinase 0.0456 0.0958 0.0947
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0323 0.0578 0.0578
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0332 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Plasmodium falciparum thioredoxin reductase 0.3606 1 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0384 0.0754 0.0754
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Loa Loa (eye worm) one IG domain family member 0.0166 0.0128 0.0116
Echinococcus multilocularis roundabout 2 0.0384 0.0754 0.0754
Loa Loa (eye worm) protein kinase domain-containing protein 0.044 0.0913 0.0903
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0354 0.1007
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0448 0.0936 0.0925
Onchocerca volvulus 0.0673 0.1581 0.7255
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0171 0.0142 0.0106
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0332 0.0602 0.0568
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0332 0.0602 0.1506
Brugia malayi casein kinase I 0.0224 0.0293 0.0282
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0506 0.1102 0.1102
Schistosoma mansoni serine/threonine protein kinase 0.103 0.2608 0.2599
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Trypanosoma cruzi Protein kinase B 0.0339 0.0623 0.0589
Echinococcus granulosus neurogenic locus protein delta 0.0364 0.0696 0.0696
Toxoplasma gondii casein kinase I 0.0224 0.0293 0.0258
Brugia malayi intracellular kinase 0.0265 0.0412 0.0401
Brugia malayi Delta serrate ligand family protein 0.0364 0.0696 0.0685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.07 0.0689
Brugia malayi Immunoglobulin I-set domain containing protein 0.0259 0.0394 0.0383
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0231 0.0313 0.0313
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0252 0.0374 0.0339
Brugia malayi phosphoinositide-dependent protein kinase I 0.0168 0.0132 0.0121
Brugia malayi protein kinase C3,putative 0.0325 0.0584 0.0573
Brugia malayi Protein kinase domain containing protein 0.0651 0.1518 0.1508
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) hypothetical protein 0.0199 0.0223 0.0211
Schistosoma mansoni protein kinase 0.0206 0.0243 0.0231
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0467 0.0991 0.0991
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0506 0.1102 0.1102
Echinococcus multilocularis serine:threonine protein kinase 0.0235 0.0326 0.0326
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0166 0.0128 0.0116
Plasmodium falciparum calcium-dependent protein kinase 2 0.0208 0.0247 0.0212
Plasmodium falciparum protein kinase 5 0.0245 0.0354 0.0319
Schistosoma mansoni peroxidasin 0.02 0.0224 0.0213
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0354 0.1007
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0167 0.0129 0.0094
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0313 0.0278
Echinococcus granulosus epidermal growth factor receptor 0.0495 0.107 0.107
Brugia malayi ephrin receptor 1 precursor 0.0129 0.0021 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Echinococcus multilocularis Immunoglobulin 0.0199 0.0223 0.0223
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0199 0.0223 0.0223
Schistosoma mansoni glutamate synthase 0.0332 0.0602 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0293 0.0282
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0265 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0247 0.0358 0.0347
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0181 0.0169
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) hypothetical protein 0.0199 0.0223 0.0211
Entamoeba histolytica protein kinase, putative 0.0177 0.0159 0.0707
Brugia malayi Immunoglobulin I-set domain containing protein 0.0199 0.0223 0.0211
Echinococcus granulosus expressed protein 0.0171 0.0142 0.0142
Leishmania major protein kinase A catalytic subunit isoform 1 0.0233 0.0319 0.0284
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0558 0.1252 0.1252
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0328 0.0593 0.0559
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Trypanosoma cruzi cdc2-related kinase 1 0.0245 0.0354 0.0319
Brugia malayi Leucine Rich Repeat family protein 0.0167 0.0129 0.0118
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0237 0.0332 0.0332
Giardia lamblia Kinase, CMGC GSK 0.0265 0.0412 0.0893
Schistosoma mansoni tyrosine kinase 0.0709 0.1685 0.1675
Giardia lamblia Kinase, AGC PKA 0.0233 0.0319 0.0594
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0317 0.056 0.0526
Echinococcus multilocularis casein kinase I delta 0.0224 0.0293 0.0293
Echinococcus granulosus nephrin 0.0185 0.0181 0.0181
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0173 0.0146 0.011
Loa Loa (eye worm) SRC-1 0.0314 0.055 0.0539
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.125 0.3237 0.3237
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.125 0.3237 1
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0398 0.1148
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0381 0.0745 0.0734
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0177 0.0159 0.0159
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0146 0.011
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1021 0.258 0.258
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0396 0.0385
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0332 0.0602 0.1783
Leishmania major protein kinase, putative 0.0208 0.0247 0.0212
Trypanosoma cruzi hypothetical protein, conserved 0.0332 0.0602 0.0568
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0366 0.07 0.0689
Brugia malayi Protein kinase domain containing protein 0.0353 0.0663 0.0652
Brugia malayi EGF-like domain containing protein 0.0364 0.0696 0.0685
Echinococcus multilocularis fibropellin Ia 0.0364 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0199 0.0223 0.0211
Echinococcus granulosus serine:threonine protein kinase N2 0.06 0.1372 0.1372
Echinococcus granulosus roundabout 2 0.0384 0.0754 0.0754
Brugia malayi basement membrane proteoglycan 0.0199 0.0223 0.0211
Leishmania major hypothetical protein, conserved 0.0332 0.0602 0.0568
Trichomonas vaginalis AGC family protein kinase 0.034 0.0626 0.1858
Echinococcus multilocularis dual specificity 0.0287 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0208 0.0247 0.0236
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0339 0.0622 0.0622
Schistosoma mansoni ste20-related kinase 0.0423 0.0865 0.0855
Schistosoma mansoni titin 0.0166 0.0128 0.0116
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0242 0.0344 0.1723
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0728 0.174 0.174
Giardia lamblia Glutamate synthase 0.0332 0.0602 0.1506
Echinococcus granulosus Protein kinase C brain isozyme 0.0503 0.1094 0.1094
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0146 0.0359
Trichomonas vaginalis AGC family protein kinase 0.0353 0.0663 0.1974
Brugia malayi Muscle positioning protein 4 0.0364 0.0696 0.0685
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0456 0.0958 0.0958
Loa Loa (eye worm) AGC/PKA protein kinase 0.0233 0.0319 0.0308
Brugia malayi EGF-like domain containing protein 0.0364 0.0696 0.0685
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0344 0.0978
Brugia malayi hypothetical protein 0.0134 0.0036 0.0024
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0174 0.0151 0.0662
Trypanosoma cruzi NADH dehydrogenase, putative 0.0332 0.0602 0.0568
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0313 0.0301
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0252 0.0374 0.0339
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0316 0.0557 0.0546
Loa Loa (eye worm) hypothetical protein 0.0953 0.2386 0.2377
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0328 0.0593 0.0559
Schistosoma mansoni protein kinase 0.0896 0.2222 0.2213
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.026 0.0396 0.0385
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0384 0.0754 0.0754
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0171 0.0142 0.0106
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0265 0.0412 0.0401
Loa Loa (eye worm) hypothetical protein 0.0199 0.0223 0.0211
Echinococcus multilocularis serine:threonine protein kinase 38 0.0332 0.0603 0.0603
Brugia malayi Immunoglobulin I-set domain containing protein 0.0384 0.0754 0.0743
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0384 0.0754 0.0754
Trichomonas vaginalis CAMK family protein kinase 0.0448 0.0936 0.2823
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.125 0.3237 0.3212
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0623 0.3253
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0328 0.0593 0.0559
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0339 0.0622 0.0611
Plasmodium vivax thioredoxin reductase, putative 0.3606 1 1
Plasmodium falciparum casein kinase 1 0.0224 0.0293 0.0258
Echinococcus granulosus Immunoglobulin 0.0199 0.0223 0.0223
Schistosoma mansoni tyrosine kinase 0.0428 0.0879 0.0868
Echinococcus multilocularis calcium dependent protein kinase 0.014 0.0053 0.0053
Onchocerca volvulus 0.0224 0.0293 0.1255
Brugia malayi SRC-1 0.0314 0.055 0.0539
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0757 0.1824 0.1814
Entamoeba histolytica hypothetical protein 0.0252 0.0374 0.1887
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0172 0.0145 0.0145
Trichomonas vaginalis STE family protein kinase 0.0177 0.0159 0.0401
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0314 0.055 0.055
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0332 0.0602 0.1783
Brugia malayi Prion-like- 0.0366 0.07 0.0689
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0328 0.0593 0.0582
Leishmania major protein kinase, putative 0.0317 0.056 0.0526
Schistosoma mansoni laminin gamma-3 chain 0.0364 0.0696 0.0685
Brugia malayi Temporarily assigned gene name protein 59 0.0266 0.0415 0.0404
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0344 0.0978
Schistosoma mansoni tyrosine kinase 0.0373 0.0722 0.0711
Loa Loa (eye worm) Notch2 0.0364 0.0696 0.0685
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0299 0.0508 0.0508
Echinococcus multilocularis epidermal growth factor receptor 0.0495 0.107 0.107
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0161 0.0112 0.0076
Toxoplasma gondii AGC kinase 0.0233 0.0319 0.0284
Echinococcus multilocularis PAK box P21 Rho binding 0.0132 0.0031 0.0031
Giardia lamblia Kinase, CMGC CDK 0.0245 0.0354 0.0704
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0166 0.0128 0.0128
Echinococcus multilocularis mitogen activated protein kinase 0.0173 0.0146 0.0146
Plasmodium falciparum calcium-dependent protein kinase 1 0.0208 0.0247 0.0212
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0338 0.062 0.0609
Brugia malayi Protein kinase domain containing protein 0.04 0.0798 0.0787
Echinococcus granulosus insulin receptor 0.0616 0.1419 0.1419
Toxoplasma gondii AGC kinase 0.0587 0.1336 0.1305
Echinococcus granulosus dual specificity 0.0252 0.0374 0.0374
Echinococcus granulosus peroxidasin 0.0366 0.0702 0.0702
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0092 0.0081
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0168 0.0132 0.0132
Schistosoma mansoni septate junction protein 0.0366 0.07 0.0689
Echinococcus granulosus mitogen activated protein kinase 0.0173 0.0146 0.0146
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0366 0.07 0.3149
Schistosoma mansoni protein kinase 0.0896 0.2222 0.2213
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0506 0.1102 0.1091
Schistosoma mansoni hypothetical protein 0.0332 0.0602 0.0591
Plasmodium vivax glycogen synthase kinase 3, putative 0.0265 0.0412 0.0286
Trypanosoma brucei Casein kinase II 0.0206 0.0243 0.0207
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0311 0.0543 0.0532
Echinococcus granulosus insulin growth factor binding 0.0166 0.0128 0.0128
Brugia malayi Immunoglobulin I-set domain containing protein 0.0253 0.0375 0.0364
Echinococcus multilocularis protein tyrosine kinase 0.0587 0.1336 0.1336
Echinococcus granulosus protein tyrosine kinase 0.0587 0.1336 0.1336
Echinococcus multilocularis rac serine:threonine kinase 0.0339 0.0623 0.0623
Echinococcus granulosus NCK adaptor protein 0.0126 0.0012 0.0012
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Echinococcus granulosus dual specificity 0.0287 0.0473 0.0473
Loa Loa (eye worm) casein kinase 0.0372 0.0719 0.0708
Brugia malayi Immunoglobulin domain containing protein 0.0199 0.0223 0.0211
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0092 0.0081
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0161 0.0112 0.0076
Echinococcus granulosus tyrosine protein kinase ABL1 0.0134 0.0036 0.0036
Trichomonas vaginalis STE family protein kinase 0.0174 0.0151 0.0376
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0233 0.0319 0.0319
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Schistosoma mansoni vesicular amine transporter 0.0656 0.1533 0.1523
Schistosoma mansoni tyrosine kinase 0.0495 0.107 0.106
Plasmodium falciparum NIMA related kinase 1 0.0281 0.0456 0.0422
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.125 0.3237 0.3229
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.0851 0.084
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0332 0.0602 0.3141
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0233 0.0319 0.0284
Echinococcus multilocularis serine:threonine protein kinase N2 0.0332 0.0603 0.0603
Plasmodium falciparum thioredoxin reductase 0.125 0.3237 0.3212
Plasmodium falciparum calcium-dependent protein kinase 5 0.0208 0.0247 0.0212
Brugia malayi EGF-like domain containing protein 0.041 0.0827 0.0816
Brugia malayi Protein kinase domain containing protein 0.0134 0.0036 0.0024
Brugia malayi Protein kinase domain containing protein 0.0134 0.0036 0.0024
Entamoeba histolytica hypothetical protein 0.0391 0.0772 0.4074
Brugia malayi EGF-like domain containing protein 0.0364 0.0696 0.0685
Echinococcus granulosus titin 0.0253 0.0375 0.0375
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Loa Loa (eye worm) hypothetical protein 0.0675 0.1587 0.1577
Leishmania major hypothetical protein, conserved 0.0332 0.0602 0.0568
Schistosoma mansoni cell adhesion molecule 0.0384 0.0754 0.0743
Brugia malayi Protein kinase domain containing protein 0.0289 0.0479 0.0468
Brugia malayi Fibronectin type III domain containing protein 0.0675 0.1587 0.1577
Echinococcus multilocularis neurogenic locus notch protein 0.0364 0.0696 0.0696
Entamoeba histolytica protein kinase, putative 0.0332 0.0603 0.3146
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0374 0.0363
Schistosoma mansoni sulfide quinone reductase 0.0332 0.0602 0.0591
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0233 0.0319 0.0308
Echinococcus multilocularis roundabout 2 0.104 0.2637 0.2637
Brugia malayi Tyrosine-protein kinase abl-1 0.0193 0.0203 0.0192
Trypanosoma cruzi aurora B kinase, putative 0.0242 0.0344 0.0309
Brugia malayi EGF-like domain containing protein 0.0364 0.0696 0.0685
Brugia malayi kettin 0.0166 0.0128 0.0116
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0384 0.0754 0.0743
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0252 0.0374 0.0363
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0323 0.0578 0.0544
Loa Loa (eye worm) hypothetical protein 0.0856 0.2106 0.2097
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0332 0.0602 0.0602
Entamoeba histolytica protein kinase, putative 0.0135 0.0038 0.0044
Trichomonas vaginalis glutathione reductase, putative 0.125 0.3237 1
Loa Loa (eye worm) animal heme peroxidase 0.0166 0.0128 0.0116
Loa Loa (eye worm) TK protein kinase 0.0379 0.0737 0.0726
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0926 0.2309 0.23
Entamoeba histolytica casein kinase 1, putative 0.0224 0.0293 0.1444
Loa Loa (eye worm) hypothetical protein 0.0656 0.1533 0.1523
Schistosoma mansoni protein kinase 0.0547 0.122 0.1209
Plasmodium falciparum cGMP-dependent protein kinase 0.0172 0.0145 0.0109
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0918 0.2285 0.2276
Echinococcus multilocularis raf serine:threonine protein kinase 0.0153 0.009 0.009
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0166 0.0128 0.0116
Brugia malayi serine/threonine protein kinase 6 0.0242 0.0344 0.0333
Onchocerca volvulus Putative titin 0.0166 0.0128 0.0482
Echinococcus granulosus serine:threonine kinase SAD 1 0.0161 0.0112 0.0112
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0208 0.0247 0.0247
Brugia malayi p70 ribosomal S6 kinase beta 0.0587 0.1336 0.1326
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0166 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0656 0.1533 0.1523
Giardia lamblia Thioredoxin reductase 0.0332 0.0602 0.1506
Echinococcus granulosus contactin 0.0384 0.0754 0.0754
Echinococcus granulosus cyclin dependent kinase 19 0.103 0.2608 0.2608
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Echinococcus multilocularis cyclin dependent kinase 0.0245 0.0354 0.0354
Plasmodium vivax unspecified product 0.0206 0.0243 0.0115
Schistosoma mansoni kinase 0.0596 0.1361 0.1351
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0181 0.047
Echinococcus multilocularis mitogen activated protein kinase 14 0.0328 0.0593 0.0593
Echinococcus multilocularis lachesin 0.0366 0.07 0.07
Brugia malayi Casein kinase II, alpha chain 0.0206 0.0243 0.0231
Echinococcus granulosus N chimaerin 0.0154 0.0092 0.0092
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0185 0.0181 0.0169
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Echinococcus granulosus casein kinase I delta 0.0224 0.0293 0.0293
Echinococcus granulosus dual specificity 0.0287 0.0473 0.0473
Onchocerca volvulus 0.0673 0.1581 0.7255
Schistosoma mansoni g1/s-specific cyclin C 0.1516 0.4 0.3993
Echinococcus granulosus casein kinase ii subunit alpha 0.0206 0.0243 0.0243
Loa Loa (eye worm) hypothetical protein 0.0657 0.1535 0.1525
Brugia malayi C1-like domain containing protein 0.0449 0.0939 0.0929
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Echinococcus granulosus protein kinase C gamma type 0.0416 0.0846 0.0846
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) thioredoxin reductase 0.3606 1 1
Giardia lamblia Kinase, CMGC CK2 0.0206 0.0243 0.0347
Echinococcus granulosus aurora kinase A 0.0242 0.0344 0.0344
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0412 0.119
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Loa Loa (eye worm) hypothetical protein 0.0185 0.0181 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0558 0.1252 0.1241
Brugia malayi Prion-like- 0.0166 0.0128 0.0116
Schistosoma mansoni titin 0.0253 0.0375 0.0364
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1252 0.122
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0235 0.0326 0.0314
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0344 0.0333
Brugia malayi Protein kinase domain containing protein 0.0245 0.0354 0.0342
Trypanosoma brucei cdc2-related kinase 3 0.0245 0.0354 0.0319
Loa Loa (eye worm) hypothetical protein 0.0366 0.07 0.0689
Schistosoma mansoni protein kinase 0.0177 0.0159 0.0148
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0317 0.056 0.0526
Loa Loa (eye worm) hypothetical protein 0.0295 0.0497 0.0486
Trichomonas vaginalis AGC family protein kinase 0.0281 0.0456 0.1328
Echinococcus multilocularis protein jagged 2 0.0364 0.0696 0.0696
Onchocerca volvulus 0.0185 0.0181 0.0731
Brugia malayi Protein kinase domain containing protein 0.0728 0.174 0.173
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0332 0.0602 0.0568
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0208 0.0247 0.0212
Echinococcus granulosus nervana 2 0.0255 0.0384 0.0384
Echinococcus granulosus neural cadherin 0.0364 0.0696 0.0696
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Schistosoma mansoni protein kinase 0.0896 0.2222 0.2213
Onchocerca volvulus 0.0134 0.0036 0.0054
Entamoeba histolytica protein kinase, putative 0.0242 0.0344 0.1723
Schistosoma mansoni tyrosine kinase 0.0193 0.0203 0.0192
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0199 0.0223 0.0211
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0332 0.0602 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0332 0.0603 0.0592
Entamoeba histolytica serine/threonine protein kinase, putative 0.0161 0.0112 0.0448
Schistosoma mansoni c4b-binding protein beta chain 0.0673 0.1581 0.1571
Trichomonas vaginalis apoptosis inducing factor, putative 0.0332 0.0602 0.1783
Trichomonas vaginalis CK1 family protein kinase 0.0224 0.0293 0.082
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Echinococcus granulosus protein kinase c iota type 0.059 0.1343 0.1343
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0233 0.0319 0.0284
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0112 0.01
Brugia malayi Protein kinase domain containing protein 0.0398 0.0792 0.0782
Echinococcus multilocularis nervana 2 0.0255 0.0384 0.0384
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0479 0.1025 0.1015
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0208 0.0247 0.0247
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0364 0.0696 0.0685
Schistosoma mansoni tyrosine kinase 0.0616 0.1419 0.1408
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0245 0.0354 0.0342
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0245 0.0354 0.0342
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0688 0.1625 0.1615
Loa Loa (eye worm) hypothetical protein 0.0287 0.0473 0.0462
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0418 0.0851 0.084
Loa Loa (eye worm) hypothetical protein 0.0184 0.018 0.0168
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.026 0.0396 0.0385
Schistosoma mansoni septate junction protein 0.0199 0.0223 0.0211
Onchocerca volvulus 0.0645 0.1502 0.6884
Brugia malayi Protein kinase domain containing protein 0.0134 0.0036 0.0024
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0199 0.0223 0.0223
Echinococcus multilocularis mitogen activated protein kinase 3 0.0173 0.0146 0.0146
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0328 0.0593 0.0559
Schistosoma mansoni titin 0.0185 0.0181 0.0169
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0814 0.1986 0.1977
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0233 0.0319 0.0284
Brugia malayi Immunoglobulin I-set domain containing protein 0.0199 0.0223 0.0211
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0332 0.0602 0.0479
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0467 0.0991 0.0991
Giardia lamblia Kinase, CMGC CLK 0.0317 0.056 0.137
Leishmania major protein kinase A catalytic subunit isoform 2 0.0233 0.0319 0.0284
Onchocerca volvulus 0.0671 0.1577 0.7234
Schistosoma mansoni tyrosine kinase 0.0616 0.1419 0.1408
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0142 0.013
Giardia lamblia Kinase, CMGC GSK 0.0265 0.0412 0.0893
Echinococcus granulosus raf serine:threonine protein kinase 0.0153 0.009 0.009
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0473 0.2432
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0459 0.0967 0.0967
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0208 0.0247 0.0119
Schistosoma mansoni septate junction protein 0.0366 0.07 0.0689
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0651 0.1518 0.1508
Loa Loa (eye worm) TK protein kinase 0.0255 0.0383 0.0371
Trypanosoma cruzi casein kinase, putative 0.0224 0.0293 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) TK/FER protein kinase 0.0446 0.0931 0.092
Trypanosoma brucei trypanothione reductase 0.3606 1 1
Schistosoma mansoni tyrosine kinase 0.0428 0.0879 0.0868
Brugia malayi protein kinase C II. 0.0421 0.0859 0.0848
Loa Loa (eye worm) TK/INSR protein kinase 0.0616 0.1419 0.1408
Brugia malayi P38 map kinase family protein 2 0.0328 0.0593 0.0582
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0332 0.0602 0.3141
Echinococcus granulosus titin 0.0166 0.0128 0.0128
Echinococcus multilocularis tyrosine protein kinase Blk 0.0255 0.0383 0.0383
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Brugia malayi serine/threonine-protein kinase plk-2 0.0558 0.1252 0.1241
Giardia lamblia Kinase, AGC PKA 0.0323 0.0578 0.1427
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Loa Loa (eye worm) hypothetical protein 0.0235 0.0326 0.0314
Giardia lamblia High cysteine protein 0.0364 0.0696 0.1808
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0353 0.0663 0.0652
Mycobacterium tuberculosis Probable oxidoreductase 0.125 0.3237 0.2803
Loa Loa (eye worm) hypothetical protein 0.0222 0.0288 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0339 0.0622 0.0611
Onchocerca volvulus 0.0364 0.0696 0.313
Loa Loa (eye worm) hypothetical protein 0.0675 0.1587 0.1577
Schistosoma mansoni tyrosine kinase 0.0193 0.0203 0.0192
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0656 0.1533 0.1523
Leishmania major protein kinase, putative 0.0317 0.056 0.0526
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0173 0.0146 0.011
Giardia lamblia Kinase, CMGC MAPK 0.0173 0.0146 0.0034
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0313 0.0278
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0473 0.138
Brugia malayi Immunoglobulin domain containing protein 0.0199 0.0223 0.0211
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0364 0.1833
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0412 0.119
Onchocerca volvulus 0.0166 0.0128 0.0482
Brugia malayi Kinase associated domain 1 family protein 0.021 0.0254 0.0243
Brugia malayi Cam kinase protein 1 0.0208 0.0247 0.0236
Brugia malayi Protein kinase domain containing protein 0.0127 0.0016 0.0004
Echinococcus multilocularis twitchin 0.0234 0.0322 0.0322
Echinococcus multilocularis down syndrome cell adhesion 0.0166 0.0128 0.0128
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0241 0.0343 0.0332
Brugia malayi GCC2 and GCC3 family protein 0.1037 0.2627 0.2618
Entamoeba histolytica casein kinase, putative 0.0224 0.0293 0.1444
Entamoeba histolytica protein kinase, putative 0.0171 0.0142 0.0612
Echinococcus multilocularis titin 0.0253 0.0375 0.0375
Echinococcus multilocularis transfer RNA-Phe 0.0185 0.0181 0.0181
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0314 0.055 0.055
Trypanosoma cruzi hypothetical protein, conserved 0.0332 0.0602 0.0568
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.125 0.3237 0.3212
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0317 0.056 0.0549
Echinococcus granulosus defective proboscis extension response 0.0656 0.1533 0.1533
Echinococcus multilocularis titin 0.0166 0.0128 0.0128
Onchocerca volvulus 0.0287 0.0473 0.2092
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0208 0.0247 0.0212
Echinococcus granulosus notch 0.0364 0.0696 0.0696
Onchocerca volvulus 0.0673 0.1581 0.7255
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.093 0.0919
Schistosoma mansoni roundabout 0.0366 0.07 0.0689
Echinococcus granulosus twitchin 0.089 0.2205 0.2205
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0265 0.0412 0.0401
Onchocerca volvulus Serine\/threonine kinase homolog 0.0339 0.0622 0.2786
Loa Loa (eye worm) hypothetical protein 0.0619 0.1426 0.1416
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0332 0.0602 0.1783
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0473 0.138
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0276 0.0265
Schistosoma mansoni protein kinase 0.0316 0.0557 0.0546
Schistosoma mansoni hypothetical protein 0.0185 0.0181 0.0169
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0421 0.0859 0.0848
Echinococcus multilocularis cyclin 0.0756 0.1819 0.1819
Echinococcus multilocularis 0.0196 0.0214 0.0214
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0319 0.0901
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0174 0.0151 0.0115
Trichomonas vaginalis CK1 family protein kinase 0.0224 0.0293 0.082
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.125 0.3237 1
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0112 0.01
Echinococcus multilocularis neurogenic locus notch protein 0.0364 0.0696 0.0696
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.125 0.3237 0.3212
Schistosoma mansoni serine/threonine protein kinase 0.0728 0.174 0.173
Brugia malayi Fes/CIP4 homology domain containing protein 0.0211 0.0256 0.0244
Brugia malayi Immunoglobulin I-set domain containing protein 0.0675 0.1587 0.1577
Loa Loa (eye worm) hypothetical protein 0.0246 0.0356 0.0344
Echinococcus multilocularis protein jagged 1 0.0364 0.0696 0.0696
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0166 0.0128 0.0116
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0673 0.1581 0.1571
Echinococcus granulosus thioredoxin glutathione reductase 0.3606 1 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0558 0.1252 0.1252
Echinococcus granulosus dual specificity 0.0287 0.0473 0.0473
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.093 0.093
Brugia malayi Protein kinase domain containing protein 0.0185 0.0181 0.017
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0172 0.0145 0.0109
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.07 0.0689
Entamoeba histolytica protein kinase , putative 0.0242 0.0344 0.1723
Toxoplasma gondii histone kinase SNF1, putative 0.0161 0.0112 0.0076
Echinococcus multilocularis dual specificity 0.0287 0.0473 0.0473
Trichomonas vaginalis CAMK family protein kinase 0.0208 0.0247 0.0675
Schistosoma mansoni atypical protein kinase C 0.0602 0.1379 0.1369
Echinococcus multilocularis casein kinase I alpha 0.0224 0.0293 0.0293
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0313 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0181 0.017
Schistosoma mansoni protein kinase 0.0398 0.0792 0.0782
Echinococcus multilocularis Glutaredoxin protein 5 0.0255 0.0384 0.0384
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0173 0.0146 0.011
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0173 0.0146 0.011
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0459 0.0967 0.0956
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Entamoeba histolytica protein kinase, putative 0.0603 0.1381 0.7421
Schistosoma mansoni nephrin related 0.0166 0.0128 0.0116
Trypanosoma cruzi casein kinase, putative 0.0224 0.0293 0.0258
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0155 0.0389
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0332 0.0602 0.1783
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0199 0.0223 0.0223
Brugia malayi Protein kinase domain containing protein 0.0616 0.1419 0.1408
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0384 0.0754 0.0754
Echinococcus multilocularis tyrosine protein kinase Srms 0.0255 0.0383 0.0383
Brugia malayi Cadherin domain containing protein 0.0364 0.0696 0.0685
Echinococcus multilocularis serine:threonine protein kinase N2 0.06 0.1372 0.1372
Brugia malayi Protein kinase domain containing protein 0.0926 0.2309 0.23
Schistosoma mansoni protein kinase 0.0456 0.0958 0.0947
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0449 0.0437
Plasmodium falciparum calcium-dependent protein kinase 3 0.0208 0.0247 0.0212
Brugia malayi Protein kinase domain containing protein 0.0603 0.1381 0.1371
Echinococcus multilocularis nervana 2 0.0255 0.0384 0.0384
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0366 0.07 0.0689
Schistosoma mansoni tyrosine kinase 0.0587 0.1336 0.1325
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0332 0.0602 0.0568
Onchocerca volvulus 0.0166 0.0128 0.0482
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0366 0.07 0.07
Echinococcus multilocularis myosin iiia 0.0174 0.0151 0.0151
Loa Loa (eye worm) CDC7 protein kinase 0.0185 0.0181 0.017
Brugia malayi serine/threonine kinase 12 0.0242 0.0344 0.0333
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Giardia lamblia Kinase, STE STE20 0.0174 0.0151 0.0051
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0757 0.1824 0.1824
Schistosoma mansoni vav2 0.017 0.0137 0.0125
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0332 0.0602 0.0602
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0332 0.0602 0.0568
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1498 0.3949 0.3949
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0485 0.1043 0.1043
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0332 0.0602 0.0602
Schistosoma mansoni titin 0.0166 0.0128 0.0116
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.125 0.3237 0.3212
Echinococcus multilocularis Immunoglobulin 0.0656 0.1533 0.1533
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.093 0.093
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0177 0.0159 0.0159
Giardia lamblia NADH oxidase lateral transfer candidate 0.125 0.3237 1
Brugia malayi Doublecortin family protein 0.0311 0.0543 0.0532
Echinococcus granulosus epidermal growth factor receptor 0.0709 0.1685 0.1685
Loa Loa (eye worm) hypothetical protein 0.0132 0.003 0.0018
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0332 0.0602 0.0568
Loa Loa (eye worm) hypothetical protein 0.0373 0.0721 0.071
Echinococcus multilocularis casein kinase i 0.0224 0.0293 0.0293
Brugia malayi Immunoglobulin domain containing protein 0.0199 0.0223 0.0211
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0473 0.138
Schistosoma mansoni tyrosine kinase 0.0428 0.0879 0.0868
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0332 0.0602 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.056 0.0549
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0728 0.174 0.174
Brugia malayi Hr1 repeat family protein 0.06 0.1372 0.1362
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0814 0.1986 0.1986
Schistosoma mansoni cell adhesion molecule 0.0199 0.0223 0.0211
Loa Loa (eye worm) AGC/PKG protein kinase 0.0172 0.0145 0.0133
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0287 0.0473 0.0439
Echinococcus multilocularis casein kinase I alpha 0.0224 0.0293 0.0293
Echinococcus multilocularis c4b binding protein beta chain 0.0673 0.1581 0.1581
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Brugia malayi Thioredoxin reductase 0.3606 1 1
Schistosoma mansoni notch 0.0364 0.0696 0.0685
Schistosoma mansoni cell adhesion molecule 0.0366 0.07 0.0689
Toxoplasma gondii selenide, water dikinase 0.0332 0.0602 0.0568
Onchocerca volvulus 0.0134 0.0036 0.0054
Brugia malayi protein unc-22 0.0253 0.0375 0.0364
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0174 0.0151 0.0115
Giardia lamblia Kinase, NEK 0.0281 0.0456 0.1036
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0146 0.011
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0558 0.1252 0.122
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.056 0.0549
Echinococcus multilocularis mitogen activated protein kinase 14 0.0328 0.0593 0.0593
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0206 0.0243 0.0115
Loa Loa (eye worm) AGC/PKA protein kinase 0.0233 0.0319 0.0308
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0473 0.0439
Echinococcus granulosus protein kinase c epsilon type 0.0421 0.0859 0.0859
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0449 0.0939 0.0929
Loa Loa (eye worm) hypothetical protein 0.1022 0.2583 0.2574
Echinococcus multilocularis hemicentin 1 0.0366 0.07 0.07
Onchocerca volvulus 0.0673 0.1581 0.7255
Entamoeba histolytica protein kinase, putative 0.0168 0.0132 0.0559
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0265 0.0412 0.0412
Schistosoma mansoni cell adhesion molecule 0.0874 0.2159 0.215
Entamoeba histolytica protein kinase domain containing protein 0.0206 0.0243 0.1166
Giardia lamblia Kinase, AGC AKT 0.0241 0.0343 0.0671
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.125 0.3237 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0233 0.0319 0.0308
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0166 0.0128 0.0128
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0166 0.0128 0.0116
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0233 0.0319 0.0192
Entamoeba histolytica disulphide oxidoreductase, putative 0.0332 0.0602 0.3141
Onchocerca volvulus 0.0295 0.0497 0.2204
Toxoplasma gondii CMGC kinase, CK2 family 0.0206 0.0243 0.0207
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0255 0.0384 0.0384
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0414 0.0839 0.0829
Schistosoma mansoni notch 0.0364 0.0696 0.0685
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0255 0.0383 0.0383
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0199 0.0223 0.0211
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0242 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0495 0.107 0.107
Onchocerca volvulus 0.0167 0.0129 0.0489
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0344 0.0333
Schistosoma mansoni growth factor receptor-bound protein 0.0128 0.0018 0.0006
Onchocerca volvulus Putative cubilin 0.0364 0.0696 0.313
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0319 0.0308
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0332 0.0602 0.1783
Loa Loa (eye worm) hypothetical protein 0.0748 0.1798 0.1788
Schistosoma mansoni notch 0.0364 0.0696 0.0685
Brugia malayi EGF-like domain containing protein 0.0364 0.0696 0.0685
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0177 0.0159 0.0159
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.07 0.0689
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0168 0.0132 0.0132
Plasmodium falciparum glycogen synthase kinase 3 0.0265 0.0412 0.0377
Trypanosoma cruzi casein kinase, putative 0.0224 0.0293 0.0258
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Schistosoma mansoni cell adhesion molecule 0.0185 0.0181 0.0169
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0218 0.0276 0.0276
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0199 0.0223 0.0223
Echinococcus granulosus tyrosine protein kinase Fyn 0.0314 0.055 0.055
Schistosoma mansoni serine/threonine protein kinase 0.0414 0.0839 0.0829
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Onchocerca volvulus 0.0673 0.1581 0.7255
Loa Loa (eye worm) hypothetical protein 0.0366 0.0702 0.0691
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0166 0.0128 0.0116
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.125 0.3237 0.3212
Echinococcus granulosus lachesin 0.0366 0.07 0.07
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0354 0.0342
Giardia lamblia Kinase, STE STE20 0.0177 0.0159 0.0077
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Echinococcus multilocularis neurogenic locus notch protein 4 0.0364 0.0696 0.0696
Schistosoma mansoni netrin receptor unc5 0.0199 0.0223 0.0211
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0038 0.0044
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0485 0.1043 0.1043
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1252 0.3808
Trypanosoma cruzi casein kinase, putative 0.0224 0.0293 0.0258
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.0344 0.1723
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0384 0.0754 0.0754
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0255 0.0384 0.0384
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0152 0.0087 0.0076
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.125 0.3237 0.3212
Echinococcus multilocularis tyrosine protein kinase Src42A 0.019 0.0197 0.0197
Loa Loa (eye worm) projectin 0.0185 0.0181 0.0169
Echinococcus multilocularis neural cadherin 0.0364 0.0696 0.0696
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0199 0.0223 0.0211
Echinococcus granulosus neurogenic locus notch protein 0.0364 0.0696 0.0696
Trichomonas vaginalis glutamate synthase, putative 0.0332 0.0602 0.1783
Echinococcus multilocularis cyclin dependent kinase 5 0.0245 0.0354 0.0354
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0896 0.2222 0.2222
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0314 0.055 0.055
Echinococcus multilocularis aurora kinase A 0.0242 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1567 0.4149 0.4142
Echinococcus multilocularis 0.0316 0.0557 0.0557
Entamoeba histolytica protein kinase, putative 0.0287 0.0473 0.2432
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Leishmania major dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Entamoeba histolytica protein kinase, putative 0.0603 0.1381 0.7421
Brugia malayi Temporarily assigned gene name protein 59 0.0231 0.0313 0.0301
Trypanosoma brucei hypothetical protein, conserved 0.0332 0.0602 0.0568
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.125 0.3237 0.3212
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0257 0.0388 0.0353
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0651 0.1518 0.1508
Schistosoma mansoni hypothetical protein 0.0199 0.0223 0.0211
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0208 0.0247 0.0236
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1043 0.1032
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0473 0.0462
Brugia malayi Protein kinase domain containing protein 0.0171 0.0142 0.013
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.125 0.3237 1
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Schistosoma mansoni septate junction protein 0.0364 0.0696 0.0685
Echinococcus multilocularis dual specificity 0.0287 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0366 0.07 0.0689
Trichomonas vaginalis AGC family protein kinase 0.0369 0.0708 0.2114
Loa Loa (eye worm) gastrulation defective protein 1 0.0963 0.2413 0.2405
Echinococcus multilocularis 0.0249 0.0366 0.0366
Echinococcus multilocularis casein kinase I delta 0.0224 0.0293 0.0293
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0154 0.0092 0.0092
Brugia malayi cell division control protein 2 homolog 0.0245 0.0354 0.0342
Echinococcus granulosus neuroglian 0.0384 0.0754 0.0754
Onchocerca volvulus Slit protein homolog 0.041 0.0827 0.3741
Echinococcus multilocularis roundabout 2 0.0384 0.0754 0.0754
Echinococcus multilocularis rho associated protein kinase 0.0671 0.1577 0.1577
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0177 0.0159 0.0159
Loa Loa (eye worm) cyclin C 0.1516 0.4 0.3993
Brugia malayi Prion-like- 0.0166 0.0128 0.0116
Echinococcus multilocularis Immunoglobulin 0.0656 0.1533 0.1533
Trypanosoma brucei protein kinase, putative 0.0265 0.0412 0.0377
Brugia malayi MAP kinase sur-1 0.0173 0.0146 0.0134
Echinococcus granulosus tyrosine protein kinase Fyn 0.0314 0.055 0.055
Echinococcus granulosus serine:threonine protein kinase 0.0235 0.0326 0.0326
Plasmodium vivax apical sushi protein, putative 0.0673 0.1581 0.1471
Onchocerca volvulus 0.0132 0.003 0.0027
Echinococcus granulosus calcium dependent protein kinase 0.014 0.0053 0.0053
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.103 0.2608 0.2599
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0161 0.0112 0.0112
Echinococcus multilocularis Immunoglobulin subtype 0.0199 0.0223 0.0223
Schistosoma mansoni titin 0.0166 0.0128 0.0116
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Plasmodium vivax casein kinase 1, putative 0.0224 0.0293 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.0967 0.0956
Schistosoma mansoni hypothetical protein 0.0166 0.0128 0.0116
Echinococcus granulosus Immunoglobulin 0.0199 0.0223 0.0223
Echinococcus granulosus basement membrane specific heparan sulfate 0.0199 0.0223 0.0223
Echinococcus granulosus protein kinase shaggy 0.0265 0.0412 0.0412
Onchocerca volvulus 0.0397 0.079 0.3568
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0446 0.0931 0.0931
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0299 0.0507 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0985 0.2477 0.2468
Schistosoma mansoni protein kinase C mu 0.0449 0.0939 0.0929
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.093 0.0919
Brugia malayi Egg laying defective protein 4 0.0172 0.0145 0.0133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0259 0.0247
Giardia lamblia Kinase, CMGC CDK 0.0245 0.0354 0.0704
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0323 0.0578 0.0544
Onchocerca volvulus 0.0364 0.0696 0.313
Schistosoma mansoni hemicentin 0.0185 0.0181 0.0169
Schistosoma mansoni glutamate synthase 0.0332 0.0602 0.0591
Onchocerca volvulus 0.0134 0.0036 0.0054
Plasmodium falciparum serine/threonine protein kinase KIN 0.0161 0.0112 0.0076
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0728 0.174 0.7992
Loa Loa (eye worm) hypothetical protein 0.0214 0.0265 0.0253
Loa Loa (eye worm) hypothetical protein 0.0199 0.0223 0.0211
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1945 0.5234 0.5228
Trypanosoma brucei SNF1-related protein kinases, putative 0.0161 0.0112 0.0076
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0245 0.0354 0.0342
Echinococcus granulosus mitogen activated protein kinase 14 0.0328 0.0593 0.0593
Brugia malayi Prion-like- 0.0166 0.0128 0.0116
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0418 0.0851 0.0851
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Echinococcus granulosus hemicentin 1 0.0366 0.07 0.07
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0177 0.0159 0.0159
Onchocerca volvulus 0.0185 0.0181 0.0731
Loa Loa (eye worm) hypothetical protein 0.0231 0.0313 0.0301
Echinococcus multilocularis serine threonine protein kinase 0.0416 0.0846 0.0846
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0166 0.0128 0.0128
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0285 0.0469 0.1368
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0181 0.047
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0208 0.0247 0.0236
Echinococcus granulosus protein jagged 2 0.0364 0.0696 0.0696
Schistosoma mansoni cell adhesion molecule 0.0199 0.0223 0.0211
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0412 0.2096
Echinococcus granulosus protein kinase 0.0316 0.0557 0.0557
Entamoeba histolytica protein kinase, putative 0.0242 0.0344 0.1723
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0208 0.0247 0.0119
Onchocerca volvulus 0.0166 0.0128 0.0482
Schistosoma mansoni protein kinase 0.0132 0.0031 0.0019
Schistosoma mansoni nephrin 0.0384 0.0754 0.0743
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0332 0.0602 0.0568
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0252 0.0374 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0195 0.0184
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.125 0.3237 0.2803
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0169 0.0135 0.0006
Echinococcus multilocularis hemicentin 1 0.0366 0.07 0.07
Brugia malayi SH2 domain containing protein 0.0134 0.0036 0.0024
Toxoplasma gondii NADPH-glutathione reductase 0.125 0.3237 0.3212
Echinococcus multilocularis dual specificity protein kinase clk2 0.0317 0.056 0.056
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0199 0.0223 0.0223
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0208 0.0247 0.0212
Entamoeba histolytica protein kinase, putative 0.0148 0.0075 0.0246
Brugia malayi Protein kinase domain containing protein 0.0448 0.0936 0.0925
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0373 0.0722 0.0722
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0134 0.0036 0.0029
Echinococcus multilocularis cyclin dependent kinase 1 0.0245 0.0354 0.0354
Trypanosoma brucei cdc2-related kinase 1 0.0245 0.0354 0.0319
Loa Loa (eye worm) hypothetical protein 0.1037 0.2627 0.2618
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0414 0.0839 0.0839
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0332 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0295 0.0497 0.0486
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0224 0.0293 0.0282
Schistosoma mansoni cell adhesion molecule 0.0166 0.0128 0.0116
Schistosoma mansoni neuroglian 0.0384 0.0754 0.0743
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0132 0.0121
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0354 0.1007
Brugia malayi glutamate synthase 0.0332 0.0602 0.0591
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0199 0.0223 0.0211
Schistosoma mansoni hypothetical protein 0.0166 0.0128 0.0116
Brugia malayi Cadherin domain containing protein 0.0364 0.0696 0.0685
Brugia malayi Cyclin C 0.1516 0.4 0.3993
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0242 0.0344 0.0218
Echinococcus granulosus cyclin dependent kinase 5 0.0245 0.0354 0.0354
Schistosoma mansoni rap gtpase-activating protein 0.0231 0.0313 0.0301
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1275 0.3881
Echinococcus granulosus roundabout 2 0.104 0.2637 0.2637
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0193 0.0203 0.0192
Entamoeba histolytica serine/threonine protein kinase, putative 0.0558 0.1252 0.671
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0332 0.0602 0.0568
Onchocerca volvulus 0.0166 0.0128 0.0482
Onchocerca volvulus 0.0364 0.0696 0.313
Echinococcus multilocularis tyrosine kinase 0.0134 0.0036 0.0036
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0332 0.0602 0.1783
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0242 0.0344 0.0344
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0756 0.1819 0.1819
Leishmania major casein kinase, putative 0.0224 0.0293 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.044 0.0913 0.0903
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0172 0.0145 0.0145
Echinococcus multilocularis NCK adaptor protein 0.0128 0.0018 0.0018
Trypanosoma brucei polo-like protein kinase 0.0558 0.1252 0.122
Echinococcus multilocularis glutamate synthase 0.0332 0.0602 0.0602
Echinococcus granulosus protein jagged 2 0.0364 0.0696 0.0696
Onchocerca volvulus 0.0604 0.1383 0.6329
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.0332 0.0939
Brugia malayi Protein kinase c protein 2 0.0239 0.0335 0.0324
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0317 0.056 0.0526
Echinococcus multilocularis neurogenic locus protein delta 0.0364 0.0696 0.0696
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Echinococcus multilocularis tyrosine protein kinase shark 0.0354 0.0666 0.0666
Echinococcus multilocularis ephrin type A receptor 4 A 0.0199 0.0221 0.0221
Leishmania major acetoin dehydrogenase e3 component-like protein 0.125 0.3237 0.3212
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0856 0.2106 0.2106
Schistosoma mansoni hypothetical protein 0.0199 0.0223 0.0211
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0323 0.0578 0.0454
Loa Loa (eye worm) hypothetical protein 0.0134 0.0036 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.02 0.0224 0.0213
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0332 0.0602 0.0602
Onchocerca volvulus 0.0364 0.0696 0.313
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0212 0.0259 0.0247
Schistosoma mansoni hypothetical protein 0.0231 0.0313 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0449 0.0437
Echinococcus granulosus serine/threonine protein kinase 0.0339 0.0623 0.0623
Trypanosoma cruzi trypanothione reductase, putative 0.125 0.3237 0.3212
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Toxoplasma gondii AGC kinase 0.0233 0.0319 0.0284
Echinococcus granulosus serine:threonine protein kinase 3 0.053 0.1172 0.1172
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Loa Loa (eye worm) hypothetical protein 0.0651 0.1518 0.1508
Echinococcus granulosus tyrosine protein kinase 0.0313 0.0549 0.0549
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Brugia malayi pregnancy-associated plasma protein-A 0.0673 0.1581 0.1571
Schistosoma mansoni serine/threonine protein kinase 0.0332 0.0603 0.0592
Onchocerca volvulus Peroxidasin homolog 0.0166 0.0128 0.0482
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Brugia malayi Protein kinase domain containing protein 0.0252 0.0374 0.0363
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.125 0.3237 0.2803
Giardia lamblia Kinase, NEK 0.0281 0.0456 0.1036
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0242 0.0344 0.1723
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0156 0.0099 0.0063
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Trichomonas vaginalis mercuric reductase, putative 0.125 0.3237 1
Brugia malayi Serine/threonine-protein kinase SULU 0.0459 0.0967 0.0956
Echinococcus granulosus cyclin 0.0756 0.1819 0.1819
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0173 0.0146 0.0134
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Schistosoma mansoni tyrosine kinase 0.0433 0.0892 0.0881
Schistosoma mansoni slit 0.0167 0.0129 0.0118
Trichomonas vaginalis CMGC family protein kinase 0.0317 0.056 0.1652
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0323 0.0578 0.0578
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0896 0.2222 0.2222
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.125 0.3237 0.3148
Echinococcus granulosus tyrosine protein kinase otk 0.0366 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0231 0.0313 0.0301
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Plasmodium vivax glutathione reductase, putative 0.3606 1 1
Echinococcus granulosus protein jagged 1 0.0364 0.0696 0.0696
Toxoplasma gondii rhoptry neck protein RON1 0.0673 0.1581 0.1551
Schistosoma mansoni tyrosine kinase 0.0411 0.0829 0.0818
Brugia malayi map kinase activated protein kinase protein 2 0.0814 0.1986 0.1977
Echinococcus multilocularis titin 0.0166 0.0128 0.0128
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0281 0.0456 0.0422
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0339 0.0623 0.0589
Schistosoma mansoni tyrosine kinase 0.0314 0.055 0.0539
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1252 0.122
Echinococcus granulosus serine:threonine protein kinase N2 0.0268 0.0419 0.0419
Schistosoma mansoni titin 0.0166 0.0128 0.0116
Echinococcus granulosus C type lectin domian containing protein 0.0673 0.1581 0.1581
Plasmodium falciparum ferrodoxin reductase-like protein 0.0332 0.0602 0.0568
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0364 0.1833
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0181 0.047
Loa Loa (eye worm) hypothetical protein 0.0366 0.07 0.0689
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0373 0.0722 0.0722
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0373 0.0722 0.0722
Loa Loa (eye worm) hypothetical protein 0.0249 0.0366 0.0355
Plasmodium falciparum casein kinase 2, alpha subunit 0.0206 0.0243 0.0207
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0176 0.0155 0.0144
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0233 0.0319 0.0284
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Leishmania major casein kinase II, putative 0.0206 0.0243 0.0207
Echinococcus multilocularis mitogen activated protein kinase 11 0.0328 0.0593 0.0593
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0412 0.2096
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0185 0.0181 0.0181
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Leishmania major NADH dehydrogenase, putative 0.0332 0.0602 0.0568
Brugia malayi Sushi domain 0.0673 0.1581 0.1571
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) hypothetical protein 0.021 0.0254 0.0243
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0545 0.1216 0.1206
Brugia malayi putative serine/threonine kinase SADA gamma 0.0161 0.0112 0.01
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0459 0.0967 0.0967
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0206 0.0243 0.0231
Schistosoma mansoni titin 0.0166 0.0128 0.0116
Echinococcus granulosus casein kinase I alpha 0.0224 0.0293 0.0293
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0757 0.1824 0.1824
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0623 0.3253
Schistosoma mansoni netrin receptor unc5 0.0259 0.0394 0.0383
Loa Loa (eye worm) hypothetical protein 0.041 0.0827 0.0816
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0317 0.056 0.0526
Loa Loa (eye worm) hypothetical protein 0.0397 0.079 0.0779
Echinococcus granulosus cyclin dependent kinase 1 0.0245 0.0354 0.0354
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Loa Loa (eye worm) hypothetical protein 0.038 0.074 0.0729
Echinococcus multilocularis titin 0.0166 0.0128 0.0128
Plasmodium vivax calcium-dependent protein kinase, putative 0.0208 0.0247 0.0119
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0245 0.0354 0.0319
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0339 0.0622 0.0622
Echinococcus granulosus nervana 2 0.0255 0.0384 0.0384
Trypanosoma cruzi NADH dehydrogenase, putative 0.0332 0.0602 0.0568
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1021 0.258 0.258
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0208 0.0247 0.0247
Entamoeba histolytica casein kinase, putative 0.0206 0.0243 0.1166
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0317 0.056 0.0526
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0332 0.0603 0.0603
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0364 0.0696 0.0685
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0299 0.0508 0.0508
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0171 0.0142 0.0106
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Onchocerca volvulus 0.0166 0.0128 0.0482
Echinococcus multilocularis tyrosine protein kinase Abl 0.0193 0.0203 0.0203
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0245 0.0354 0.0354
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0265 0.0412 0.0377
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0174 0.0151 0.0115
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0199 0.0223 0.0211
Brugia malayi Protein kinase domain containing protein 0.0757 0.1824 0.1814
Giardia lamblia Kinase, CMGC DYRK 0.0287 0.0473 0.109
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0456 0.0958 0.0958
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0233 0.0319 0.0284
Brugia malayi Protein kinase domain 0.0177 0.0159 0.0148
Entamoeba histolytica cell division protein kinase 2, putative 0.0245 0.0354 0.1775
Entamoeba histolytica protein kinase, putative 0.0188 0.0189 0.0869
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0231 0.0313 0.0313
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0688 0.1625 0.1615
Onchocerca volvulus 0.0166 0.0128 0.0482
Plasmodium falciparum apical sushi protein 0.0673 0.1581 0.1551
Echinococcus granulosus tyrosine kinase 0.0255 0.0383 0.0383
Leishmania major protein kinase A catalytic subunit 0.0233 0.0319 0.0284
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0245 0.0354 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.1161 0.1151
Echinococcus granulosus cyclin dependent kinase 0.0245 0.0354 0.0354
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0332 0.0603 0.0603
Loa Loa (eye worm) hypothetical protein 0.0168 0.0133 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0814 0.1986 0.1986
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0623 0.0612
Echinococcus multilocularis peroxidasin 0.0366 0.0702 0.0702
Echinococcus multilocularis c src tyrosine kinase 0.0193 0.0203 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Echinococcus granulosus c-Jun N-terminal kinases 0.0545 0.1216 0.1216
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0317 0.056 0.0526
Loa Loa (eye worm) programmed cell death 8 0.0332 0.0602 0.0591
Schistosoma mansoni notch 0.0364 0.0696 0.0685
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.125 0.3237 0.3229
Echinococcus multilocularis protein jagged 1 0.0364 0.0696 0.0696
Echinococcus multilocularis protein kinase c epsilon type 0.0421 0.0859 0.0859
Loa Loa (eye worm) hypothetical protein 0.0177 0.0159 0.0148
Schistosoma mansoni serine/threonine kinase 0.0332 0.0603 0.0592
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0224 0.0293 0.0282
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.125 0.3237 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0233 0.0319 0.0284
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0344 0.0978
Echinococcus multilocularis tyrosine protein kinase otk 0.0366 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0366 0.07 0.0689
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0265 0.0412 0.0377
Treponema pallidum NADH oxidase 0.125 0.3237 1
Entamoeba histolytica protein kinase, putative 0.0171 0.0142 0.0612
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0224 0.0293 0.0282
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0332 0.0602 0.0568
Echinococcus multilocularis cyclin dependent kinase 1 0.0245 0.0354 0.0354
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0181 0.0169
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0252 0.0374 0.0339
Giardia lamblia Kinase, NEK 0.0281 0.0456 0.1036
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0623 0.0612
Onchocerca volvulus Tyrosine kinase homolog 0.0878 0.2171 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0299 0.0507 0.0507
Echinococcus granulosus tyrosine protein kinase Fyn 0.0314 0.055 0.055
Echinococcus multilocularis netrin receptor unc 5 0.0259 0.0394 0.0394
Trypanosoma brucei casein kinase I, isoform 2 0.0224 0.0293 0.0258
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0332 0.0602 0.0602
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0473 0.0439
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0174 0.0151 0.0662
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.125 0.3237 0.3148
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0699 0.1655 0.1646
Schistosoma mansoni hypothetical protein 0.021 0.0254 0.0243
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0332 0.0602 0.0602
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0287 0.0473 0.0462
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Echinococcus granulosus dual specificity protein kinase clk2 0.0317 0.056 0.056
Brugia malayi EGF-like domain containing protein 0.0364 0.0696 0.0685
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0199 0.0223 0.0211
Loa Loa (eye worm) AGC/NDR protein kinase 0.0332 0.0603 0.0592
Leishmania major protein kinase, putative 0.0174 0.0151 0.0115
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1252 0.3808
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0332 0.0602 0.0568
Loa Loa (eye worm) hypothetical protein 0.0332 0.0602 0.0591
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0317 0.056 0.0526
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0449 0.0939 0.0929
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0224 0.0293 0.0258
Onchocerca volvulus 0.0673 0.1581 0.7255
Schistosoma mansoni myosin-binding protein-related 0.0185 0.0181 0.0169
Onchocerca volvulus 0.0185 0.0181 0.0733
Schistosoma mansoni slit 0.0365 0.0698 0.0687
Loa Loa (eye worm) CAMK protein kinase 0.0253 0.0375 0.0364
Echinococcus granulosus tyrosine protein kinase Lyn 0.0381 0.0744 0.0744
Plasmodium falciparum calcium-dependent protein kinase 4 0.0208 0.0247 0.0212
Brugia malayi Myb-like DNA-binding domain containing protein 0.0166 0.0128 0.0116
Brugia malayi serine/threonine-protein kinase PAK 7 0.0479 0.1025 0.1015
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0167 0.0129 0.0129
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0332 0.0602 0.0568
Echinococcus multilocularis mitogen activated protein kinase 11 0.0328 0.0593 0.0593
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0503 0.1094 0.1094
Brugia malayi Protein kinase domain containing protein 0.0235 0.0326 0.0314
Entamoeba histolytica thioredoxin reductase, putative 0.0332 0.0602 0.3141
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0332 0.0602 0.3141
Toxoplasma gondii rhoptry neck protein RON9 0.0673 0.1581 0.1551
Schistosoma mansoni tyrosine kinase 0.0354 0.0666 0.0655
Schistosoma mansoni cell polarity protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Onchocerca volvulus 0.0156 0.0099 0.035
Plasmodium falciparum serine/threonine protein kinase 0.0171 0.0142 0.0106
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0314 0.055 0.055
Echinococcus multilocularis death associated protein kinase 1 0.0906 0.2251 0.2251
Brugia malayi Protein kinase domain containing protein 0.0134 0.0036 0.0024
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0154 0.0092 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0132 0.0317
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0313 0.0278
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.125 0.3237 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0545 0.1216 0.1206
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0265 0.0412 0.0377
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0332 0.0602 0.0568
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0314 0.055 0.055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Schistosoma mansoni hypothetical protein 0.0166 0.0128 0.0116
Entamoeba histolytica protein kinase, putative 0.0587 0.1336 0.7175
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0364 0.0696 0.313
Brugia malayi Immunoglobulin I-set domain containing protein 0.1567 0.4149 0.4142
Plasmodium falciparum glutathione reductase 0.125 0.3237 0.3212
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0332 0.0602 0.0591
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.125 0.3237 1
Echinococcus granulosus rho-associated protein kinase 1 0.0671 0.1577 0.1577
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0181 0.0169
Schistosoma mansoni tyrosine kinase 0.0286 0.0472 0.0461
Echinococcus granulosus fibropellin Ia 0.0364 0.0696 0.0696
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Echinococcus granulosus glutamate synthase 0.0332 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0398 0.0792 0.0782
Echinococcus granulosus fibroblast growth factor receptor 4 0.0373 0.0722 0.0722
Brugia malayi Immunoglobulin I-set domain containing protein 0.0384 0.0754 0.0743
Echinococcus multilocularis dual specificity 0.0252 0.0374 0.0374
Echinococcus multilocularis fat cadherin tumor suppressor 0.0364 0.0696 0.0696
Brugia malayi Protein kinase domain containing protein 0.0134 0.0036 0.0024
Echinococcus multilocularis activin receptor type 0.0134 0.0036 0.0036
Schistosoma mansoni notch 0.0364 0.0696 0.0685
Schistosoma mansoni hypothetical protein 0.021 0.0254 0.0243
Plasmodium vivax serine/threonine kinase-1, putative 0.0317 0.056 0.0436
Brugia malayi Stress-activated protein kinase jnk-1 0.0545 0.1216 0.1206
Trichomonas vaginalis STE family protein kinase 0.0281 0.0456 0.1328
Brugia malayi Protein kinase domain containing protein 0.031 0.054 0.0529
Loa Loa (eye worm) thyroid receptor interactor 0.0211 0.0256 0.0244
Brugia malayi Immunoglobulin I-set domain containing protein 0.054 0.1199 0.1189
Trypanosoma brucei NADH dehydrogenase 0.0332 0.0602 0.0568
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0332 0.0602 0.1783
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Onchocerca volvulus Netrin receptor homolog 0.0226 0.0299 0.1281
Schistosoma mansoni serine/threonine protein kinase 0.0671 0.1577 0.1567
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0314 0.055 0.055
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0242 0.0344 0.1723
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0332 0.0602 0.0568
Loa Loa (eye worm) notch protein 0.0364 0.0696 0.0685
Leishmania major trypanothione reductase 0.3606 1 1
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0208 0.0247 0.0236
Echinococcus granulosus neurogenic locus notch protein 4 0.0364 0.0696 0.0696
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1381 0.4212
Echinococcus granulosus roundabout 2 0.0384 0.0754 0.0754
Loa Loa (eye worm) AGC/PKN protein kinase 0.06 0.1372 0.1362
Echinococcus granulosus Immunoglobulin 0.0656 0.1533 0.1533
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0233 0.0319 0.0319
Loa Loa (eye worm) LAD-2 short isoform 0.0199 0.0223 0.0211
Loa Loa (eye worm) hypothetical protein 0.1022 0.2583 0.2574
Loa Loa (eye worm) TK protein kinase 0.054 0.1199 0.1189
Schistosoma mansoni basigin related 0.0199 0.0223 0.0211
Toxoplasma gondii aurora kinase 0.0242 0.0344 0.0309
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0173 0.0146 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.07 0.0689
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0656 0.1533 0.1523
Schistosoma mansoni ephrin receptor 0.0199 0.0221 0.021
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0199 0.0223 0.0223
Echinococcus granulosus hypothetical protein 0.0249 0.0366 0.0366
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0233 0.0319 0.0284
Schistosoma mansoni disulfide oxidoreductase 0.0332 0.0602 0.0591
Entamoeba histolytica p21-activated kinase 0.0193 0.0204 0.0953
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0354 0.0342
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Echinococcus granulosus casein kinase I alpha 0.0224 0.0293 0.0293
Giardia lamblia Kinase, CMGC SRPK 0.0171 0.0142 0.0022
Brugia malayi Animal haem peroxidase family protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0253 0.0375 0.0364
Echinococcus granulosus cGMP dependent protein kinase 1 0.0172 0.0145 0.0145
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0177 0.0159 0.0159
Trypanosoma brucei aurora B kinase 0.0242 0.0344 0.0309
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0185 0.0181 0.0169
Echinococcus multilocularis insulin receptor 0.0616 0.1419 0.1419
Entamoeba histolytica protein kinase, putative 0.0148 0.0075 0.0246
Toxoplasma gondii thioredoxin reductase 0.3606 1 1
Trypanosoma cruzi casein kinase II, putative 0.0206 0.0243 0.0207
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0332 0.0602 0.0602
Plasmodium falciparum serine/threonine protein kinase, putative 0.0242 0.0344 0.0309
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Echinococcus granulosus c4b binding protein beta chain 0.0673 0.1581 0.1581
Echinococcus multilocularis thioredoxin glutathione reductase 0.3606 1 1
Schistosoma mansoni protein kinase 0.0242 0.0344 0.0333
Echinococcus granulosus tyrosine kinase 0.0134 0.0036 0.0036
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0208 0.0247 0.0119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.125 0.3237 0.3212
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0452 0.0948 0.0937
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0154 0.0092 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0421 0.0859 0.0848
Echinococcus granulosus growth factor receptor bound protein 2 0.0128 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0366 0.07 0.0689
Echinococcus granulosus c src tyrosine kinase 0.0193 0.0203 0.0203
Schistosoma mansoni serine/threonine kinase 0.0456 0.0959 0.0948
Loa Loa (eye worm) glutathione reductase 0.3606 1 1
Echinococcus granulosus Vam6:Vps39 protein 0.0231 0.0313 0.0313
Schistosoma mansoni nephrin 0.0841 0.2064 0.2055
Echinococcus multilocularis Immunoglobulin 0.0199 0.0223 0.0223
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.053 0.1172 0.1162
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0145 0.0133
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0814 0.1986 0.1977
Echinococcus granulosus tyrosine protein kinase Src64B 0.0314 0.055 0.055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0181 0.0169
Brugia malayi basement membrane proteoglycan precursor 0.0199 0.0223 0.0211
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0319 0.0308
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0167 0.0129 0.0094
Echinococcus multilocularis protein kinase shaggy 0.0265 0.0412 0.0412
Trypanosoma brucei protein kinase, putative 0.0181 0.0169 0.0133
Echinococcus multilocularis neurogenic locus protein delta 0.0364 0.0696 0.0696
Echinococcus multilocularis CDC7 cell division cycle 7 0.0185 0.0181 0.0181
Schistosoma mansoni nephrin related 0.0199 0.0223 0.0211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.07 0.0689
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0146 0.0359
Brugia malayi hypothetical protein 0.0673 0.1581 0.1571
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0199 0.0223 0.0223
Echinococcus multilocularis hypothetical protein 0.021 0.0254 0.0254
Plasmodium falciparum protein serine/threonine kinase-1 0.0317 0.056 0.0526
Schistosoma mansoni hypothetical protein 0.0166 0.0128 0.0116
Brugia malayi serine/threonine-protein kinase 6 0.0242 0.0344 0.0333
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0314 0.055 0.055
Echinococcus granulosus ephrin type A receptor 4 A 0.0199 0.0221 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.0332 0.0939
Echinococcus multilocularis serine:threonine protein kinase N2 0.0268 0.0419 0.0419
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0265 0.0412 0.0401
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Trypanosoma cruzi trypanothione reductase, putative 0.3606 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Entamoeba histolytica protein kinase, putative 0.0252 0.0374 0.1887
Onchocerca volvulus 0.0673 0.1581 0.7255
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1043 0.1032
Schistosoma mansoni hypothetical protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0243 0.0662
Brugia malayi Calcium binding EGF domain containing protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0161 0.0112 0.01
Loa Loa (eye worm) TK/FAK protein kinase 0.0593 0.1353 0.1343
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0418 0.0851 0.0851
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0319 0.0319
Trichomonas vaginalis STE family protein kinase 0.0177 0.0159 0.0401
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0332 0.0602 0.3141
Onchocerca volvulus 0.0381 0.0745 0.3359
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) hypothetical protein 0.0384 0.0754 0.0743
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.0326 0.0921
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Schistosoma mansoni septate junction protein 0.0199 0.0223 0.0211
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0332 0.0602 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0375 0.0364
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0479 0.1025 0.1025
Echinococcus multilocularis serine:threonine protein kinase 3 0.053 0.1172 0.1172
Echinococcus granulosus Glutaredoxin protein 5 0.0255 0.0384 0.0384
Brugia malayi notch-like transmembrane receptor 0.0364 0.0696 0.0685
Echinococcus granulosus NDR protein kinase 0.0332 0.0603 0.0603
Loa Loa (eye worm) hypothetical protein 0.0675 0.1587 0.1577
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0344 0.0333
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0332 0.0602 0.0568
Loa Loa (eye worm) hypothetical protein 0.0161 0.0112 0.01
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0332 0.0602 0.0591
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Echinococcus multilocularis expressed conserved protein 0.0172 0.0145 0.0145
Echinococcus granulosus tyrosine protein kinase Src42A 0.0314 0.055 0.055
Loa Loa (eye worm) TK protein kinase 0.0188 0.0189 0.0177
Loa Loa (eye worm) TK/EGFR protein kinase 0.0709 0.1685 0.1675
Brugia malayi Protein kinase domain containing protein 0.0313 0.0549 0.0538
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0332 0.0602 0.0602
Echinococcus multilocularis neuroglian 0.0384 0.0754 0.0754
Onchocerca volvulus 0.0134 0.0036 0.0054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Brugia malayi Disorganized muscle protein 1 0.0166 0.0128 0.0116
Brugia malayi SH2 domain containing protein 0.0446 0.0931 0.092
Echinococcus multilocularis calcium activated potassium channel 0.0278 0.0449 0.0449
Entamoeba histolytica protein kinase, putative 0.0252 0.0374 0.1887
Echinococcus multilocularis slit 2 protein 0.041 0.0827 0.0827
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.07 0.0689
Echinococcus granulosus cGMP dependent protein kinase 1 0.0172 0.0145 0.0145
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0287 0.0473 0.0462
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0287 0.0473 0.0439
Trypanosoma cruzi cdc2-related kinase 3 0.0245 0.0354 0.0319
Plasmodium vivax protein kinase Crk2 0.0245 0.0354 0.0227
Brugia malayi Protein kinase domain containing protein 0.0414 0.0839 0.0829
Brugia malayi Heparan sulfate 0.0199 0.0223 0.0211
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0314 0.055 0.055
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0319 0.0308
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0161 0.0112 0.0076
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0332 0.0602 0.0568
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.174 0.173
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0161 0.0112 0.0076
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0656 0.1533 0.1533
Onchocerca volvulus 0.0332 0.0602 0.2694
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Echinococcus granulosus leucine rich repeat containing protein 4 0.0166 0.0128 0.0128
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0332 0.0602 0.0568
Brugia malayi hypothetical protein 0.0459 0.0967 0.0956
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.125 0.3237 0.3212
Loa Loa (eye worm) hypothetical protein 0.0366 0.07 0.0689
Echinococcus granulosus calcium activated potassium channel 0.0278 0.0449 0.0449
Echinococcus granulosus Immunoglobulin subtype 0.0199 0.0223 0.0223
Schistosoma mansoni tyrosine kinase 0.0314 0.055 0.0539
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0165 0.0125 0.0125
Echinococcus granulosus cGMP dependent protein kinase 0.0172 0.0145 0.0145
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0218 0.0276 0.0276
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0281 0.0456 0.0331
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0146 0.0359
Loa Loa (eye worm) hypothetical protein 0.0231 0.0313 0.0301
Echinococcus granulosus neurogenic locus notch protein 0.0364 0.0696 0.0696
Trypanosoma cruzi cdc2-related kinase 1 0.0245 0.0354 0.0319
Schistosoma mansoni glutamate synthase 0.0332 0.0602 0.0591
Onchocerca volvulus 0.0265 0.0412 0.1807
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0112 0.0254
Brugia malayi Immunoglobulin I-set domain containing protein 0.0384 0.0754 0.0743
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0418 0.0851 0.084
Echinococcus granulosus tyrosine protein kinase Srms 0.0553 0.1239 0.1239
Echinococcus multilocularis growth factor receptor bound protein 2 0.0126 0.0012 0.0012
Echinococcus multilocularis N chimaerin 0.0154 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0314 0.055 0.055
Echinococcus granulosus tyrosine protein kinase shark 0.0354 0.0666 0.0666
Brugia malayi Protein kinase domain containing protein 0.1945 0.5234 0.5228
Echinococcus granulosus down syndrome cell adhesion 0.0166 0.0128 0.0128
Giardia lamblia Kinase, CDC7 0.0185 0.0181 0.0149
Entamoeba histolytica protein kinase domain containing protein 0.0418 0.0851 0.4506
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0449 0.0437
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0756 0.1819 0.1819
Echinococcus multilocularis protein kinase c iota type 0.059 0.1343 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.009 0.0078
Echinococcus multilocularis serine:threonine protein kinase 0.0235 0.0326 0.0326
Schistosoma mansoni cell adhesion molecule 0.0185 0.0181 0.0169
Onchocerca volvulus Serine\/threonine kinase homolog 0.0558 0.1252 0.5719
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0237 0.0332 0.0332
Brugia malayi Calcium binding EGF domain containing protein 0.0364 0.0696 0.0685
Trypanosoma cruzi casein kinase, putative 0.0224 0.0293 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0146 0.0134
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0233 0.0319 0.0284
Schistosoma mansoni hypothetical protein 0.0199 0.0223 0.0211
Echinococcus multilocularis insulin growth factor binding 0.0166 0.0128 0.0128
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.093 0.093
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0473 0.138
Plasmodium vivax ferrodoxin reductase, putative 0.0332 0.0602 0.0479
Trichomonas vaginalis STE family protein kinase 0.0177 0.0159 0.0401
Schistosoma mansoni sulfide quinone reductase 0.0332 0.0602 0.0591
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1252 0.3808
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0344 0.0978
Echinococcus multilocularis expressed protein 0.0171 0.0142 0.0142
Brugia malayi Protein kinase domain containing protein 0.0317 0.056 0.0549
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0332 0.0602 0.1783
Echinococcus granulosus titin 0.0253 0.0375 0.0375
Echinococcus granulosus casein kinase i 0.0224 0.0293 0.0293
Onchocerca volvulus 0.0364 0.0696 0.313
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0171 0.0142 0.013
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0332 0.0602 0.0568
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.174 0.173
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0112 0.01
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Trypanosoma cruzi cdc2-related kinase 3 0.0245 0.0354 0.0319
Trichomonas vaginalis STE family protein kinase 0.0177 0.0159 0.0401
Echinococcus multilocularis epidermal growth factor receptor 0.0709 0.1685 0.1685
Brugia malayi probable protein kinase 0.0547 0.122 0.1209
Echinococcus granulosus netrin receptor unc 5 0.0259 0.0394 0.0394
Schistosoma mansoni protein kinase 0.0224 0.0293 0.0282
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0132 0.0317
Schistosoma mansoni basigin related 0.0199 0.0223 0.0211
Echinococcus granulosus casein kinase I alpha 0.0224 0.0293 0.0293
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0185 0.0181 0.0169
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0165 0.0125 0.0125
Echinococcus granulosus serine threonine protein kinase nrc 0.0323 0.0578 0.0578
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.0181 0.0169
Loa Loa (eye worm) hypothetical protein 0.0185 0.0181 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0344 0.0333
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0332 0.0602 0.0479
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0314 0.055 0.055
Echinococcus granulosus tyrosine protein kinase HCK 0.0188 0.0189 0.0189
Schistosoma mansoni hypothetical protein 0.0199 0.0223 0.0211
Trichomonas vaginalis CK1 family protein kinase 0.0224 0.0293 0.082
Giardia lamblia Kinase, CK1 Casein kinase 0.0224 0.0293 0.051
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0363 0.0691 0.068
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0161 0.0112 0.0076
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Brugia malayi Furin-like cysteine rich region family protein 0.0709 0.1685 0.1675
Brugia malayi hypothetical protein 0.0199 0.0223 0.0211
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.0036 0.0031
Loa Loa (eye worm) hypothetical protein 0.0287 0.0473 0.0462
Trichomonas vaginalis AGC family protein kinase 0.0353 0.0663 0.1974
Onchocerca volvulus Neurogenic locus notch homolog 0.0364 0.0696 0.313
Loa Loa (eye worm) hypothetical protein 0.0479 0.1025 0.1015
Trichomonas vaginalis glutamate synthase, putative 0.0332 0.0602 0.1783
Echinococcus granulosus tyrosine protein kinase Blk 0.0255 0.0383 0.0383
Entamoeba histolytica cyclin C, putative 0.0767 0.185 1
Echinococcus multilocularis 0.0166 0.0128 0.0128
Onchocerca volvulus 0.0231 0.0313 0.1345
Plasmodium falciparum glutathione reductase 0.3606 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0503 0.1094 0.1083
Loa Loa (eye worm) TK/FER protein kinase 0.0134 0.0036 0.0024
Giardia lamblia Aurora kinase 0.0242 0.0344 0.0674
Echinococcus multilocularis casein kinase I gamma 0.044 0.0913 0.0913
Entamoeba histolytica cell division protein kinase 2, putative 0.0253 0.0377 0.1902
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0635 0.1472 0.1472
Loa Loa (eye worm) hypothetical protein 0.0673 0.1581 0.1571
Echinococcus granulosus casein kinase I gamma 0.044 0.0913 0.0913
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0314 0.055 0.055
Schistosoma mansoni hypothetical protein 0.0166 0.0128 0.0116
Brugia malayi STE20-like kinase MST 0.053 0.1172 0.1162
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0208 0.0247 0.0247
Onchocerca volvulus 0.0673 0.1581 0.7255
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3606 1 1
Schistosoma mansoni hypothetical protein 0.0364 0.0696 0.0685
Schistosoma mansoni titin 0.0366 0.07 0.0689
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0171 0.0142 0.0106
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0558 0.1252 0.1241
Brugia malayi Variant SH3 domain containing protein 0.0154 0.0092 0.0081
Brugia malayi Protein kinase domain containing protein 0.0168 0.0132 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0473 0.138
Echinococcus granulosus neuroglian 0.0822 0.2011 0.2011
Schistosoma mansoni cell adhesion molecule 0.0384 0.0754 0.0743
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1252 0.3808
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.026 0.0396 0.0396
Brugia malayi casein kinase 1, delta 0.0224 0.0293 0.0282
Schistosoma mansoni serine/threonine protein kinase 0.0503 0.1094 0.1083
Onchocerca volvulus 0.0673 0.1581 0.7255
Plasmodium vivax serine/threonine protein kinase, putative 0.0171 0.0142 0.0013
Toxoplasma gondii EGF family domain-containing protein 0.0364 0.0696 0.0662
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Schistosoma mansoni vam6/vps39 related 0.0231 0.0313 0.0301
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0112 0.01
Loa Loa (eye worm) hypothetical protein 0.0262 0.0402 0.0391
Schistosoma mansoni tyrosine kinase 0.0132 0.0028 0.0016
Loa Loa (eye worm) TK/ALK protein kinase 0.031 0.054 0.0529
Brugia malayi Peroxidasin 0.0366 0.0702 0.0691
Echinococcus granulosus titin 0.0166 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0233 0.0319 0.0308
Brugia malayi Protein kinase domain containing protein 0.044 0.0913 0.0903
Loa Loa (eye worm) hypothetical protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0384 0.0754 0.0743
Echinococcus granulosus mitogen activated protein kinase 3 0.0173 0.0146 0.0146
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0247 0.0236
Brugia malayi Immunoglobulin I-set domain containing protein 0.0166 0.0128 0.0116
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Loa Loa (eye worm) hypothetical protein 0.0364 0.0696 0.0685
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0414 0.0839 0.0839
Echinococcus granulosus delta-like protein 1 0.0364 0.0696 0.0696
Schistosoma mansoni protein kinase 0.0134 0.0036 0.0024
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0332 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0184 0.018 0.0168
Brugia malayi Calcium binding EGF domain containing protein 0.0364 0.0696 0.0685
Brugia malayi Protein kinase domain containing protein 0.0339 0.0622 0.0611
Brugia malayi Protein kinase domain containing protein 0.0593 0.1353 0.1343

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 9.8 ug ml-1 Inhibitory concentration of the compound against fatty acid synthesis in MCF-7 breast cancer cells ChEMBL. 15715465
IC50 (functional) = 9.800000000000004 ug ml-1 Inhibitory concentration of the compound against fatty acid synthesis in MCF-7 breast cancer cells ChEMBL. 15715465
IC50 (functional) = 40.5 ug ml-1 Inhibitory concentration of the compound against MCF-7 breast cancer cells in XTT assay (non radioactive assay) ChEMBL. 15715465
IC50 (functional) = 40.5 ug ml-1 Inhibitory concentration of the compound against MCF-7 breast cancer cells in XTT assay (non radioactive assay) ChEMBL. 15715465
IC50 (binding) > 50 ug ml-1 Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cells ChEMBL. 15715465
IC50 (binding) > 50 ug ml-1 Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cells ChEMBL. 15715465

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 15715465

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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