Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | checkpoint kinase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | steroid hormone receptor | 0.0083 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.1071 | 0.1071 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0044 | 0.1071 | 0.1071 |
Schistosoma mansoni | nuclear hormone receptor | 0.0083 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0083 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0083 | 1 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase I | 0.0046 | 0.1478 | 0.1478 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0083 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0083 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0044 | 0.1071 | 0.1071 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0083 | 1 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0083 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0083 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0083 | 1 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0044 | 0.1071 | 0.1071 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0083 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0046 | 0.1482 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0083 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0083 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0083 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0083 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0083 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0083 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0083 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0044 | 0.1071 | 0.1071 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0083 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0083 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0046 | 0.1482 | 0.1482 |
Brugia malayi | steroid hormone receptor | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0044 | 0.1071 | 0.1071 |
Entamoeba histolytica | protein kinase, putative | 0.0046 | 0.1482 | 0.5 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase I | 0.0046 | 0.1478 | 0.1478 |
Brugia malayi | nuclear receptor NHR-88 | 0.0083 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0083 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Brugia malayi | nuclear receptor RXR | 0.0044 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0083 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase Chk2 | 0.0046 | 0.1482 | 0.1482 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0083 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.1071 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0083 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0083 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0083 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0083 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0044 | 0.1071 | 0.1071 |
Echinococcus granulosus | serine:threonine protein kinase Chk2 | 0.0046 | 0.1482 | 0.1482 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0083 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0083 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0083 | 1 | 1 |
Onchocerca volvulus | 0.0083 | 1 | 1 | |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0083 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0083 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0083 | 1 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0083 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0083 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.