Detailed information for compound 313283

Basic information

Technical information
  • TDR Targets ID: 313283
  • Name: 1-(benzenesulfonyl)-3-[(4-sulfamoylbenzoyl)am ino]urea
  • MW: 398.414 | Formula: C14H14N4O6S2
  • H donors: 4 H acceptors: 6 LogP: 0.23 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NS(=O)(=O)c1ccccc1)NNC(=O)c1ccc(cc1)S(=O)(=O)N
  • InChi: 1S/C14H14N4O6S2/c15-25(21,22)11-8-6-10(7-9-11)13(19)16-17-14(20)18-26(23,24)12-4-2-1-3-5-12/h1-9H,(H,16,19)(H2,15,21,22)(H2,17,18,20)
  • InChiKey: DINIERFHHIBBQA-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 1-(benzenesulfonyl)-3-[[oxo-(4-sulfamoylphenyl)methyl]amino]urea
  • 1-(phenylsulfonyl)-3-[(4-sulfamoylphenyl)carbonylamino]urea
  • 1-besyl-3-[(4-sulfamoylbenzoyl)amino]urea
  • 1-phenylsulfonyl-3-[(4-sulfamoylbenzoyl)amino]urea
  • 3-[[oxo-(4-sulfamoylphenyl)methyl]amino]-1-phenylsulfonylurea
  • 1-phenylsulfonyl-3-[(4-sulfamoylphenyl)carbonylamino]urea

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase I Starlite/ChEMBL References
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References
Homo sapiens carbonic anhydrase IX Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase I 261 aa 281 aa 25.3 %
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0154 0.0224 0.0224
Echinococcus multilocularis serine:threonine protein kinase 38 0.0319 0.1008 0.1001
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0228 0.0573 0.0566
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0413 0.1453 0.1453
Schistosoma mansoni protein kinase 0.0383 0.1309 0.1309
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Entamoeba histolytica protein kinase domain containing protein 0.0233 0.0599 0.2635
Echinococcus multilocularis insulin receptor 0.0602 0.2349 0.2343
Echinococcus multilocularis lachesin 0.0245 0.0654 0.0647
Schistosoma mansoni peroxidasin 0.0132 0.012 0.012
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0327 0.1043 0.1043
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0113 0.0029 0.0021
Giardia lamblia Kinase, CMGC GSK 0.0255 0.0701 0.1531
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0076 0.0076
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0263 0.074 0.074
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0167 0.0284 0.1234
Echinococcus multilocularis cyclin dependent kinase 1 0.0235 0.0608 0.0601
Onchocerca volvulus 0.0151 0.0209 0.0623
Brugia malayi Hr1 repeat family protein 0.0578 0.2236 0.2236
Plasmodium falciparum apical sushi protein 0.0413 0.1453 0.1363
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0255 0.0701 0.0701
Echinococcus multilocularis CDC7 cell division cycle 7 0.0177 0.0333 0.0326
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.099 0.0983
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0235 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0921 0.3863 0.3863
Onchocerca volvulus 0.0131 0.0116 0.0338
Echinococcus granulosus insulin growth factor 1 receptor beta 0.062 0.2435 0.243
Schistosoma mansoni cell adhesion molecule 0.0131 0.0115 0.0115
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0242 0.064 0.0542
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0263 0.074 0.074
Onchocerca volvulus 0.0131 0.0116 0.0338
Trypanosoma cruzi NADH dehydrogenase, putative 0.0204 0.0459 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0399 0.1384 0.1384
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0551
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0573 0.1827
Onchocerca volvulus 0.0224 0.0554 0.167
Echinococcus multilocularis tyrosine protein kinase Abl 0.0188 0.0385 0.0378
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0233 0.0599 0.0592
Echinococcus multilocularis Immunoglobulin 0.0132 0.0117 0.011
Brugia malayi Protein kinase domain containing protein 0.1879 0.8405 0.8405
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0402 0.1402 0.1402
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.064 0.2526 0.2526
Echinococcus granulosus mitogen activated protein kinase 0.0165 0.0276 0.0268
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0402 0.1402 0.1395
Trichomonas vaginalis STE family protein kinase 0.027 0.0772 0.2463
Toxoplasma gondii aurora kinase 0.0233 0.0599 0.05
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0114 0.0031 0.0024
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0442 0.1587 0.1581
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0204 0.0459 0.0452
Brugia malayi Delta serrate ligand family protein 0.0224 0.0554 0.0554
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Onchocerca volvulus 0.0128 0.0099 0.0286
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0364 0.1218 0.1212
Echinococcus granulosus tyrosine protein kinase Blk 0.025 0.0676 0.0669
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus dual specificity protein kinase clk2 0.0305 0.0938 0.0931
Onchocerca volvulus 0.0224 0.0554 0.167
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0154 0.0224 0.0224
Echinococcus multilocularis transfer RNA-Phe 0.0131 0.0115 0.0108
Plasmodium falciparum calcium-dependent protein kinase 1 0.0199 0.0438 0.0337
Schistosoma mansoni septate junction protein 0.0245 0.0654 0.0654
Plasmodium vivax protein kinase Crk2 0.0235 0.0608 0.0367
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0215 0.0512 0.0512
Echinococcus granulosus raf serine:threonine protein kinase 0.0149 0.0198 0.0191
Echinococcus multilocularis serine:threonine protein kinase N2 0.0259 0.0721 0.0714
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0198 0.0198
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.027 0.0772 0.0675
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Loa Loa (eye worm) notch protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0447 0.1614 0.1614
Entamoeba histolytica protein kinase, putative 0.0161 0.0254 0.11
Echinococcus granulosus tyrosine kinase 0.025 0.0676 0.0669
Onchocerca volvulus 0.0255 0.0701 0.2117
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0226 0.0563 0.0563
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0204 0.0459 0.0688
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0306 0.0946 0.0939
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0442 0.1587 0.1587
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0509 0.0509
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0204 0.0459 0.0359
Echinococcus multilocularis tyrosine protein kinase HCK 0.0183 0.0362 0.0355
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) hypothetical protein 0.0211 0.0495 0.0495
Brugia malayi Fibronectin type III domain containing protein 0.0465 0.17 0.17
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0114 0.0031 0.0024
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0276 0.0276
Onchocerca volvulus 0.0131 0.0115 0.0337
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Schistosoma mansoni tyrosine kinase 0.0602 0.2349 0.2349
Schistosoma mansoni cell adhesion molecule 0.0132 0.0117 0.0117
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0252 0.0689 0.0689
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0233 0.0599 0.2635
Schistosoma mansoni protein kinase 0.0215 0.0512 0.0512
Echinococcus multilocularis myosin iiia 0.0167 0.0284 0.0277
Echinococcus multilocularis tyrosine kinase 0.0131 0.0116 0.0109
Loa Loa (eye worm) hypothetical protein 0.0238 0.0619 0.0619
Loa Loa (eye worm) hypothetical protein 0.0204 0.0459 0.0459
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0204 0.0459 0.0452
Giardia lamblia Kinase, CDC7 0.0177 0.0333 0.0248
Echinococcus granulosus cGMP dependent protein kinase 0.0167 0.0284 0.0277
Echinococcus granulosus neurogenic locus protein delta 0.0224 0.0554 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Loa Loa (eye worm) one IG domain family member 0.0113 0.0029 0.0029
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0204 0.0459 0.1464
Brugia malayi basement membrane proteoglycan 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0178 0.0338 0.0338
Trichomonas vaginalis apoptosis inducing factor, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0254 0.0254
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0129 0.0104 0.0104
Onchocerca volvulus 0.0224 0.0554 0.167
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0131 0.0115 0.0108
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.062 0.2435 0.243
Brugia malayi SH2 domain containing protein 0.044 0.1578 0.1578
Brugia malayi Protein kinase domain containing protein 0.0601 0.2343 0.2343
Echinococcus multilocularis protein tyrosine kinase 0.0579 0.224 0.2234
Schistosoma mansoni protein kinase 0.0527 0.1992 0.1992
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi C1-like domain containing protein 0.0432 0.1544 0.1544
Echinococcus granulosus low density lipoprotein receptor ldl 0.0132 0.0117 0.011
Onchocerca volvulus 0.0413 0.1453 0.4401
Echinococcus multilocularis cyclin dependent kinase 1 0.0235 0.0608 0.0601
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Giardia lamblia Kinase, CK1 Casein kinase 0.0215 0.0512 0.0871
Schistosoma mansoni nephrin related 0.0113 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Plasmodium falciparum glutathione reductase 0.2215 1 1
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0204 0.0459 0.2012
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Giardia lamblia Kinase, AGC PKA 0.0224 0.0553 0.1015
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0692 0.2775 0.2775
Leishmania major protein kinase A catalytic subunit isoform 1 0.0224 0.0553 0.0454
Schistosoma mansoni cell adhesion molecule 0.0113 0.0029 0.0029
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0188 0.0385 0.0385
Loa Loa (eye worm) hypothetical protein 0.0268 0.0765 0.0765
Echinococcus granulosus Down syndrome cell adhesion molecule 0.015 0.0204 0.0197
Echinococcus multilocularis neuroglian 0.056 0.215 0.2144
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.1528 0.1528
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Schistosoma mansoni protein kinase 0.0129 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni hypothetical protein 0.0131 0.0115 0.0115
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0306 0.0946 0.0939
Echinococcus granulosus protein jagged 1 0.0224 0.0554 0.0547
Echinococcus multilocularis Immunoglobulin 0.0447 0.1614 0.1608
Loa Loa (eye worm) hypothetical protein 0.0123 0.0076 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0442 0.1587 0.1587
Brugia malayi Variant SH3 domain containing protein 0.015 0.0203 0.0203
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0316 0.099 0.0895
Loa Loa (eye worm) casein kinase 0.036 0.12 0.12
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0702 0.2822 0.8561
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.0553 0.0454
Entamoeba histolytica protein kinase, putative 0.0141 0.0164 0.0696
Brugia malayi Casein kinase II, alpha chain 0.0198 0.0431 0.0431
Toxoplasma gondii AGC kinase 0.0566 0.2179 0.2097
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0305 0.0938 0.0843
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2215 1 1
Schistosoma mansoni tyrosine kinase 0.0306 0.0946 0.0946
Echinococcus granulosus expressed protein 0.0164 0.027 0.0262
Echinococcus multilocularis tyrosine protein kinase Fyn 0.025 0.0676 0.0669
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0467 0.1708 0.1702
Echinococcus granulosus calcium activated potassium channel 0.0267 0.076 0.0753
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0132 0.0117 0.011
Trypanosoma brucei Casein kinase II 0.0198 0.0431 0.033
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trichomonas vaginalis AGC family protein kinase 0.034 0.1106 0.3531
Entamoeba histolytica hypothetical protein 0.0386 0.1323 0.5866
Loa Loa (eye worm) TK/ALK protein kinase 0.0305 0.0941 0.0941
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0275 0.0799 0.0799
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Brugia malayi hypothetical protein 0.0131 0.0116 0.0116
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0204 0.0459 0.0459
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0319 0.1008 0.4459
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0132 0.0117 0.011
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0123 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0599 0.0599
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.073 0.2956 0.2951
Brugia malayi RhoGAP domain containing protein 0.015 0.0203 0.0203
Echinococcus multilocularis nervana 2 0.0247 0.0664 0.0657
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0214 0.0509 0.0509
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Trichomonas vaginalis AGC family protein kinase 0.027 0.0772 0.2463
Leishmania major protein kinase, putative 0.0305 0.0938 0.0843
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0579 0.2239 0.2233
Echinococcus multilocularis neuroglian 0.0263 0.074 0.0734
Schistosoma mansoni cell adhesion molecule 0.0132 0.0117 0.0117
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0424 0.1506 0.15
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0164 0.027 0.027
Echinococcus multilocularis tyrosine protein kinase 0.0309 0.0957 0.095
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.1038 0.1038
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0199 0.0438 0.0193
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0242 0.064 0.064
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0566 0.2179 0.2179
Giardia lamblia Thioredoxin reductase 0.0204 0.0459 0.0688
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0608 0.0608
Echinococcus granulosus c4b binding protein beta chain 0.0413 0.1453 0.1447
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0165 0.0276 0.0276
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0224 0.0553 0.0553
Echinococcus granulosus tyrosine kinase 0.0131 0.0116 0.0109
Echinococcus granulosus protein kinase 0.0304 0.0933 0.0926
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Loa Loa (eye worm) hypothetical protein 0.0463 0.1689 0.1689
Trypanosoma brucei polo-like protein kinase 0.0538 0.2043 0.1959
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0165 0.0276 0.0174
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0768 0.3134 0.3062
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.146 0.642 0.6417
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0132 0.0117 0.011
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0132 0.0117 0.0117
Entamoeba histolytica protein kinase , putative 0.0233 0.0599 0.2635
Echinococcus granulosus protein kinase shaggy 0.0255 0.0701 0.0694
Plasmodium vivax ferrodoxin reductase, putative 0.0204 0.0459 0.0215
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.012 0.012
Brugia malayi Leucine Rich Repeat family protein 0.0114 0.0031 0.0031
Brugia malayi Animal haem peroxidase family protein 0.0113 0.0029 0.0029
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0768 0.3134 0.3062
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.044 0.1578 0.1571
Trichomonas vaginalis CAMK family protein kinase 0.0545 0.208 0.6637
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0204 0.0459 0.2012
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Entamoeba histolytica casein kinase 1, putative 0.0215 0.0512 0.2247
Echinococcus granulosus aurora kinase A 0.0233 0.0599 0.0592
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Plasmodium falciparum serine/threonine protein kinase, putative 0.0233 0.0599 0.05
Loa Loa (eye worm) TK/FER protein kinase 0.044 0.1578 0.1578
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0439 0.1577 0.157
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0199 0.0438 0.0337
Echinococcus granulosus tyrosine protein kinase Lyn 0.037 0.1248 0.1241
Schistosoma mansoni cell adhesion molecule 0.0131 0.0115 0.0115
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0199 0.0438 0.0337
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0306 0.0946 0.0939
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis neural cadherin 0.0224 0.0554 0.0547
Echinococcus granulosus fibroblast growth factor receptor 4 0.0364 0.1218 0.1212
Echinococcus multilocularis rac serine:threonine kinase 0.0326 0.1038 0.1031
Echinococcus granulosus nervana 2 0.0247 0.0664 0.0657
Leishmania major NADH dehydrogenase, putative 0.0204 0.0459 0.0359
Echinococcus multilocularis fibropellin Ia 0.0224 0.0554 0.0547
Loa Loa (eye worm) CDC7 protein kinase 0.0177 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0285 0.0845 0.0845
Brugia malayi Egg laying defective protein 4 0.0167 0.0284 0.0284
Brugia malayi Temporarily assigned gene name protein 59 0.0223 0.0551 0.0551
Trichomonas vaginalis CAMK family protein kinase 0.025 0.0679 0.2168
Toxoplasma gondii casein kinase I 0.0215 0.0512 0.0412
Entamoeba histolytica p21-activated kinase 0.0185 0.0369 0.1612
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0439 0.1577 0.157
Loa Loa (eye worm) TK/ROR protein kinase 0.0178 0.0338 0.0338
Brugia malayi serine/threonine-protein kinase plk-2 0.0538 0.2043 0.2043
Echinococcus multilocularis serine:threonine protein kinase N2 0.0319 0.1008 0.1001
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1708 0.1708
Giardia lamblia Kinase, PLK 0.0538 0.2043 0.6201
Brugia malayi Protein kinase domain containing protein 0.034 0.1106 0.1106
Schistosoma mansoni tyrosine kinase 0.0485 0.1795 0.1795
Schistosoma mansoni protein kinase 0.0304 0.0933 0.0933
Entamoeba histolytica casein kinase, putative 0.0198 0.0431 0.1887
Trichomonas vaginalis mercuric reductase, putative 0.0768 0.3134 1
Brugia malayi Protein kinase domain 0.017 0.0297 0.0297
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.0701 0.0701
Leishmania major trypanothione reductase 0.2215 1 1
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Plasmodium vivax apical sushi protein, putative 0.0413 0.1453 0.1234
Schistosoma mansoni g1/s-specific cyclin C 0.0849 0.3518 0.3518
Schistosoma mansoni slit 0.0114 0.0031 0.0031
Schistosoma mansoni tyrosine kinase 0.0579 0.224 0.224
Onchocerca volvulus 0.0285 0.0845 0.2555
Echinococcus granulosus Glutaredoxin protein 5 0.0247 0.0664 0.0657
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.0512 0.0512
Echinococcus multilocularis thioredoxin glutathione reductase 0.2215 1 1
Toxoplasma gondii thioredoxin reductase 0.2215 1 1
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0511 0.1915 0.1915
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Onchocerca volvulus 0.0113 0.0029 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0204 0.0459 0.1464
Echinococcus multilocularis N chimaerin 0.015 0.0203 0.0196
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Echinococcus multilocularis mitogen activated protein kinase 0.0165 0.0276 0.0268
Echinococcus multilocularis expressed protein 0.0164 0.027 0.0262
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Echinococcus granulosus titin 0.0195 0.0417 0.041
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0459
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0164 0.027 0.0168
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Entamoeba histolytica protein kinase, putative 0.0164 0.027 0.1169
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Echinococcus granulosus c src tyrosine kinase 0.0188 0.0385 0.0378
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Echinococcus granulosus epidermal growth factor receptor 0.0697 0.2798 0.2792
Trypanosoma brucei aurora B kinase 0.0233 0.0599 0.05
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0204 0.0459 0.0452
Loa Loa (eye worm) glutathione reductase 0.2215 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0287 0.0854 0.0848
Schistosoma mansoni protein kinase C mu 0.0432 0.1544 0.1544
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0291 0.093
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0702 0.2822 0.2817
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0405 0.1416 0.1416
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0167 0.0284 0.0284
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0311 0.0966 0.0735
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0076 0.0076
Trypanosoma cruzi trypanothione reductase, putative 0.2215 1 1
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus casein kinase I gamma 0.0424 0.1502 0.1496
Echinococcus granulosus Immunoglobulin 0.0132 0.0117 0.011
Entamoeba histolytica protein kinase, putative 0.0566 0.2179 0.968
Echinococcus multilocularis protein jagged 2 0.0224 0.0554 0.0547
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0233 0.0599 0.0358
Echinococcus multilocularis twitchin 0.0177 0.0331 0.0324
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.0509 0.0509
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0235 0.0608 0.0509
Echinococcus multilocularis activin receptor type 0.0129 0.0104 0.0096
Brugia malayi casein kinase I 0.0215 0.0512 0.0512
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0199 0.0438 0.0193
Brugia malayi Protein kinase domain containing protein 0.0582 0.2251 0.2251
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0319 0.1008 0.1001
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0432 0.1544 0.1544
Echinococcus multilocularis insulin growth factor binding 0.0113 0.0029 0.0021
Echinococcus multilocularis cyclin 0.0424 0.1506 0.15
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis Glutaredoxin protein 5 0.0247 0.0664 0.0657
Loa Loa (eye worm) TK/FAK protein kinase 0.0585 0.2269 0.2269
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0306 0.0946 0.0939
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.034 0.1106 0.1106
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0509 0.0509
Giardia lamblia Kinase, CMGC GSK 0.0255 0.0701 0.1531
Loa Loa (eye worm) TK protein kinase 0.0183 0.0362 0.0362
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0161 0.0254 0.0247
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0204 0.0459 0.0359
Echinococcus granulosus protein kinase C gamma type 0.0401 0.1395 0.1389
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0275 0.0799 0.0702
Echinococcus granulosus serine/threonine protein kinase 0.0326 0.1038 0.1031
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0287 0.0854 0.0848
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Brugia malayi Immunoglobulin I-set domain containing protein 0.0465 0.17 0.17
Schistosoma mansoni adapter molecule crk 0.0123 0.0076 0.0076
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0195 0.0417 0.0417
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0287 0.0853 0.0846
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Trypanosoma cruzi trypanothione reductase, putative 0.0768 0.3134 0.3134
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0086 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Onchocerca volvulus 0.0647 0.2562 0.7771
Echinococcus multilocularis death associated protein kinase 1 0.0892 0.3723 0.3718
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.0553 0.0553
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0287 0.0853 0.0846
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Brugia malayi notch-like transmembrane receptor 0.0224 0.0554 0.0554
Echinococcus granulosus casein kinase I delta 0.0215 0.0512 0.0505
Echinococcus granulosus NCK adaptor protein 0.0123 0.0076 0.0069
Loa Loa (eye worm) CAMK protein kinase 0.0195 0.0417 0.0417
Loa Loa (eye worm) TK/ABL protein kinase 0.0131 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.025 0.0679 0.2168
Trypanosoma cruzi NADH dehydrogenase, putative 0.0204 0.0459 0.0459
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0785 0.3216 0.3211
Entamoeba histolytica protein kinase, putative 0.0582 0.2251 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0485 0.1795 0.1795
Entamoeba histolytica protein kinase, putative 0.0233 0.0599 0.2635
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0432 0.1544 0.1544
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0785 0.3216 0.3211
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0538 0.2043 0.2037
Echinococcus granulosus protein tyrosine kinase 0.0579 0.224 0.2234
Echinococcus granulosus Immunoglobulin 0.0132 0.0117 0.011
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Echinococcus granulosus roundabout 2 0.0263 0.074 0.0734
Loa Loa (eye worm) hypothetical protein 0.0448 0.1616 0.1616
Echinococcus multilocularis cyclin dependent kinase 0.0235 0.0608 0.0601
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis dual specificity protein kinase clk2 0.0305 0.0938 0.0931
Plasmodium vivax glutathione reductase, putative 0.2215 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Brugia malayi Calcium binding EGF domain containing protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.0697 0.2798 0.2798
Brugia malayi Protein kinase domain containing protein 0.0385 0.1318 0.1318
Entamoeba histolytica cell division protein kinase 2, putative 0.0235 0.0608 0.2676
Brugia malayi Heparan sulfate 0.0132 0.0117 0.0117
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi map kinase activated protein kinase protein 2 0.0785 0.3216 0.3216
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0204 0.0459 0.0452
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0768 0.3134 0.3062
Echinococcus granulosus nephrin 0.0131 0.0115 0.0108
Echinococcus granulosus mitogen activated protein kinase 14 0.0316 0.099 0.0983
Trypanosoma brucei cdc2-related kinase 1 0.0235 0.0608 0.0509
Echinococcus multilocularis roundabout 2 0.071 0.2862 0.2856
Entamoeba histolytica protein kinase, putative 0.0582 0.2251 1
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis roundabout 2 0.0263 0.074 0.0734
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0768 0.3134 0.3062
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0276 0.0276
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Echinococcus multilocularis dual specificity 0.0242 0.064 0.0633
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0359
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.016 0.0251 0.0244
Echinococcus multilocularis fat cadherin tumor suppressor 0.0224 0.0554 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1008 0.1008
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Onchocerca volvulus Serine\/threonine kinase homolog 0.0326 0.1037 0.3136
Echinococcus granulosus serine threonine protein kinase nrc 0.0311 0.0966 0.0959
Loa Loa (eye worm) projectin 0.0131 0.0115 0.0115
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.1038 0.4593
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0255 0.0701 0.0604
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0768 0.3134 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Giardia lamblia High cysteine protein 0.0224 0.0554 0.1019
Onchocerca volvulus 0.0224 0.0554 0.167
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Mycobacterium tuberculosis Probable oxidoreductase 0.0768 0.3134 0.2803
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Trypanosoma cruzi cdc2-related kinase 1 0.0235 0.0608 0.0608
Brugia malayi Protein kinase domain containing protein 0.0383 0.1309 0.1309
Echinococcus granulosus delta-like protein 1 0.0224 0.0554 0.0547
Schistosoma mansoni cell adhesion molecule 0.0263 0.074 0.074
Echinococcus granulosus rho-associated protein kinase 1 0.0647 0.2562 0.2557
Schistosoma mansoni rap gtpase-activating protein 0.0223 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0369 0.1242 0.1242
Onchocerca volvulus 0.0131 0.0115 0.0337
Schistosoma mansoni protein kinase 0.0439 0.1577 0.1577
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0199 0.0438 0.0193
Trichomonas vaginalis glutamate synthase, putative 0.0204 0.0459 0.1464
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0132 0.0117 0.0117
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Echinococcus multilocularis 0.0193 0.0409 0.0402
Schistosoma mansoni hypothetical protein 0.0223 0.0551 0.0551
Entamoeba histolytica protein kinase, putative 0.0164 0.027 0.1169
Echinococcus granulosus cyclin dependent kinase 19 0.0601 0.2343 0.2338
Loa Loa (eye worm) hypothetical protein 0.0131 0.0115 0.0115
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0204 0.0459 0.0452
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0167 0.0284 0.1234
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0674 0.2689 0.2689
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0563 0.1798
Schistosoma mansoni protein kinase 0.017 0.0297 0.0297
Toxoplasma gondii AGC kinase 0.0224 0.0553 0.0454
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0157 0.024 0.024
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0204 0.0459 0.0359
Toxoplasma gondii rhoptry neck protein RON1 0.0413 0.1453 0.1363
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0277 0.0807 0.0807
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0551 0.0551
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0284 0.0284
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0235 0.0608 0.0509
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0417 0.0417
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0306 0.0946 0.0939
Echinococcus multilocularis tyrosine protein kinase Srms 0.025 0.0676 0.0669
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0204 0.0459 0.0359
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis mitogen activated protein kinase 11 0.0316 0.099 0.0983
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.0553 0.0311
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0215 0.0512 0.0512
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0311 0.0966 0.0959
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0252 0.0689 0.0682
Trichomonas vaginalis AGC family protein kinase 0.0161 0.0254 0.0811
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0402 0.1402 0.1402
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0204 0.0459 0.0452
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3062
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0938 0.0938
Brugia malayi cell division control protein 2 homolog 0.0235 0.0608 0.0608
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Brugia malayi ephrin receptor 1 precursor 0.0125 0.0087 0.0087
Schistosoma mansoni serine/threonine kinase 0.0439 0.1575 0.1575
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0167 0.0284 0.0182
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Loa Loa (eye worm) TK/EGFR protein kinase 0.0697 0.2798 0.2798
Schistosoma mansoni tyrosine kinase 0.031 0.0963 0.0963
Giardia lamblia Kinase, CMGC DYRK 0.0275 0.0799 0.1871
Trypanosoma brucei NADH dehydrogenase 0.0204 0.0459 0.0359
Echinococcus granulosus neural cadherin 0.0224 0.0554 0.0547
Trypanosoma brucei rac serine-threonine kinase, putative 0.0582 0.2251 0.217
Entamoeba histolytica protein kinase, putative 0.0126 0.0092 0.0376
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Entamoeba histolytica cell division protein kinase 2, putative 0.0243 0.0645 0.2842
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0551 0.0551
Brugia malayi Protein kinase domain containing protein 0.0431 0.1538 0.1538
Onchocerca volvulus Neurogenic locus notch homolog 0.0224 0.0554 0.167
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.2822 0.2822
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Brugia malayi Immunoglobulin I-set domain containing protein 0.0263 0.074 0.074
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Entamoeba histolytica disulphide oxidoreductase, putative 0.0204 0.0459 0.2012
Echinococcus granulosus protein jagged 1 0.0224 0.0554 0.0547
Brugia malayi serine/threonine protein kinase 6 0.0233 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Echinococcus granulosus neuroglian 0.0263 0.074 0.0734
Trichomonas vaginalis STE family protein kinase 0.0167 0.0284 0.0907
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.015 0.0203 0.0196
Echinococcus multilocularis down syndrome cell adhesion 0.0113 0.0029 0.0021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis glutamate synthase 0.0204 0.0459 0.0452
Brugia malayi intracellular kinase 0.0255 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Brugia malayi Immunoglobulin I-set domain containing protein 0.0157 0.024 0.024
Brugia malayi Serine/threonine-protein kinase SULU 0.0442 0.1587 0.1587
Loa Loa (eye worm) hypothetical protein 0.0128 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus cyclin dependent kinase 5 0.0235 0.0608 0.0601
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0654 0.0654
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0178 0.0338 0.0331
Schistosoma mansoni tyrosine kinase 0.0306 0.0946 0.0946
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1792 0.1792
Loa Loa (eye worm) hypothetical protein 0.0245 0.0654 0.0654
Plasmodium vivax calcium-dependent protein kinase, putative 0.0199 0.0438 0.0193
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0224 0.0553 0.0454
Schistosoma mansoni septate junction protein 0.0132 0.0117 0.0117
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0768 0.3134 0.3062
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0154 0.0224 0.0122
Brugia malayi Protein kinase c protein 2 0.0229 0.0578 0.0578
Echinococcus multilocularis tyrosine protein kinase otk 0.0245 0.0654 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0601 0.2343 0.2343
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0263 0.074 0.0734
Loa Loa (eye worm) gastrulation defective protein 1 0.0537 0.2041 0.2041
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.1268 0.5506 0.5506
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0487 0.1805 0.1805
Loa Loa (eye worm) cyclin C 0.0849 0.3518 0.3518
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0563 0.0556
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0235 0.0608 0.0608
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0076 0.0076
Leishmania major casein kinase, putative 0.0215 0.0512 0.0412
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0245 0.0654 0.0654
Leishmania major protein kinase, putative 0.0233 0.0599 0.05
Brugia malayi Protein kinase domain containing protein 0.0702 0.2822 0.2822
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0161 0.0254 0.0247
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0985 0.4165 0.4161
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0538 0.2043 0.1959
Toxoplasma gondii AGC kinase 0.0224 0.0553 0.0454
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3129
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1008 0.1008
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0383 0.1309 0.1309
Trichomonas vaginalis AGC family protein kinase 0.034 0.1106 0.3531
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1045 0.3335
Echinococcus multilocularis cyclin dependent kinase 9 0.0116 0.0045 0.0037
Onchocerca volvulus Putative cubilin 0.0224 0.0554 0.167
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0204 0.0459 0.1381
Echinococcus multilocularis neurogenic locus notch protein 0.0224 0.0554 0.0547
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0311 0.0966 0.0966
Leishmania major protein kinase A catalytic subunit 0.0224 0.0553 0.0454
Onchocerca volvulus 0.0113 0.0029 0.0073
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0768 0.3134 0.2803
Trichomonas vaginalis CAMK family protein kinase 0.0228 0.0573 0.1827
Echinococcus granulosus N chimaerin 0.015 0.0203 0.0196
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0424 0.1506 0.15
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0438 0.1396
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Schistosoma mansoni nck2/grb4 0.0123 0.0076 0.0076
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0306 0.0946 0.0939
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0224 0.0554 0.0554
Onchocerca volvulus 0.0177 0.0333 0.0997
Onchocerca volvulus 0.0177 0.0333 0.0997
Echinococcus multilocularis C type lectin domian containing protein 0.0413 0.1453 0.1447
Onchocerca volvulus 0.0369 0.1242 0.3759
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Onchocerca volvulus 0.0277 0.0807 0.2438
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Echinococcus multilocularis Immunoglobulin 0.0132 0.0117 0.011
Loa Loa (eye worm) LAD-2 short isoform 0.0132 0.0117 0.0117
Loa Loa (eye worm) AGC/AKT protein kinase 0.0582 0.2251 0.2251
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.0509 0.0509
Echinococcus multilocularis cyclin dependent kinase 5 0.0235 0.0608 0.0601
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0123 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Plasmodium falciparum thioredoxin reductase 0.0768 0.3134 0.3062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Echinococcus granulosus serine:threonine kinase SAD 1 0.0154 0.0224 0.0217
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0113 0.0029 0.0021
Plasmodium falciparum calcium-dependent protein kinase 3 0.0199 0.0438 0.0337
Schistosoma mansoni tyrosine kinase 0.0602 0.2349 0.2349
Onchocerca volvulus 0.0131 0.0116 0.0338
Loa Loa (eye worm) hypothetical protein 0.0241 0.0636 0.0636
Echinococcus granulosus Vam6:Vps39 protein 0.0223 0.0551 0.0544
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0199 0.0438 0.0337
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0252 0.0689 0.0682
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0165 0.0276 0.0174
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Echinococcus granulosus C type lectin domian containing protein 0.0413 0.1453 0.1447
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0599 0.191
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0768 0.3134 1
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0304 0.0933 0.0933
Echinococcus granulosus mitogen activated protein kinase 3 0.0165 0.0276 0.0268
Echinococcus granulosus casein kinase ii subunit alpha 0.0198 0.0431 0.0424
Brugia malayi Muscle positioning protein 4 0.0224 0.0554 0.0554
Entamoeba histolytica casein kinase, putative 0.0215 0.0512 0.2247
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Echinococcus granulosus tyrosine protein kinase Src42A 0.0186 0.0377 0.0369
Loa Loa (eye worm) hypothetical protein 0.0163 0.0264 0.0264
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0316 0.099 0.099
Loa Loa (eye worm) hypothetical protein 0.0131 0.0116 0.0116
Brugia malayi Protein kinase domain containing protein 0.0399 0.1384 0.1384
Echinococcus granulosus glutamate synthase 0.0204 0.0459 0.0452
Plasmodium vivax serine/threonine protein kinase, putative 0.0164 0.027 0.002
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1879 0.8405 0.8405
Onchocerca volvulus 0.0131 0.0116 0.0338
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Schistosoma mansoni kinase 0.0109 0.0007 0.0007
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0275 0.0799 0.0799
Entamoeba histolytica protein kinase domain containing protein 0.0402 0.1402 0.6214
Schistosoma mansoni septate junction protein 0.0132 0.0117 0.0117
Echinococcus granulosus dual specificity 0.0242 0.064 0.0633
Onchocerca volvulus 0.0223 0.0551 0.166
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0245 0.0654 0.1972
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3129
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0399 0.1384 0.1384
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0349 0.1148 0.1148
Echinococcus granulosus basement membrane specific heparan sulfate 0.0132 0.0117 0.011
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0204 0.0459 0.0452
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.0199 0.0438 0.0438
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0171 0.0306 0.0306
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0224 0.0554 0.167
Brugia malayi Protein kinase domain containing protein 0.0319 0.1008 0.1008
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0768 0.3134 0.3062
Echinococcus granulosus tyrosine protein kinase 0.0309 0.0957 0.095
Giardia lamblia Kinase, CMGC CDK 0.0235 0.0608 0.1206
Toxoplasma gondii NADPH-glutathione reductase 0.0768 0.3134 0.3062
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0284 0.0284
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0701 0.2238
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1178 0.376
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0145 0.0182 0.0182
Brugia malayi Protein kinase domain containing protein 0.064 0.2526 0.2526
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0204 0.0459 0.2012
Echinococcus granulosus Immunoglobulin 0.0447 0.1614 0.1608
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0768 0.3134 0.2958
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0167 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.046 0.1673 0.1673
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus peroxidasin 0.0245 0.0656 0.0649
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0113 0.0029 0.0029
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.027 0.0772 0.0536
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Echinococcus multilocularis protein kinase shaggy 0.0255 0.0701 0.0694
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Schistosoma mansoni glutamate synthase 0.0204 0.0459 0.0459
Schistosoma mansoni vam6/vps39 related 0.0223 0.0551 0.0551
Plasmodium vivax casein kinase 1, putative 0.0215 0.0512 0.0269
Echinococcus granulosus tyrosine protein kinase Src64B 0.0306 0.0946 0.0939
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1268 0.5506 0.5506
Echinococcus granulosus calcium dependent protein kinase 0.0136 0.0135 0.0128
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0275 0.0799 0.0702
Echinococcus granulosus Immunoglobulin subtype 0.0132 0.0117 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.0701 0.3092
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0186 0.0377 0.0369
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0204 0.0459 0.0452
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0247 0.0664 0.0657
Leishmania major protein kinase, putative 0.0199 0.0438 0.0337
Brugia malayi Immunoglobulin I-set domain containing protein 0.0189 0.0391 0.0391
Echinococcus multilocularis dual specificity 0.0275 0.0799 0.0792
Brugia malayi Cadherin domain containing protein 0.0224 0.0554 0.0554
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0263 0.074 0.074
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Brugia malayi Cyclin C 0.0849 0.3518 0.3518
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0625 0.2752
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0331 0.0331
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0702 0.2822 0.2822
Entamoeba histolytica protein kinase domain containing protein 0.0275 0.0799 0.3527
Brugia malayi Protein kinase domain containing protein 0.0235 0.0608 0.0608
Onchocerca volvulus 0.0215 0.0512 0.1541
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0459 0.1671 0.1665
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0938 0.0938
Echinococcus multilocularis hemicentin 1 0.0245 0.0654 0.0647
Leishmania major carbonic anhydrase-like protein 0.0214 0.0509 0.041
Echinococcus multilocularis serine:threonine protein kinase 3 0.0511 0.1915 0.1909
Brugia malayi EGF-like domain containing protein 0.0268 0.0765 0.0765
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0768 0.3134 0.3062
Onchocerca volvulus Putative titin 0.0113 0.0029 0.0073
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) animal heme peroxidase 0.0113 0.0029 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.015 0.0204 0.0204
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) AGC/PKG protein kinase 0.0167 0.0284 0.0284
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) TK/EPH protein kinase 0.0228 0.0574 0.0574
Schistosoma mansoni protein kinase 0.0198 0.0431 0.0431
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.0553 0.0553
Entamoeba histolytica protein kinase, putative 0.013 0.0109 0.0452
Echinococcus granulosus NDR protein kinase 0.0319 0.1008 0.1001
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Echinococcus multilocularis cyclin dependent kinase 19 0.0601 0.2343 0.2338
Brugia malayi Cam kinase protein 1 0.0199 0.0438 0.0438
Echinococcus granulosus defective proboscis extension response 0.0447 0.1614 0.1608
Echinococcus granulosus thioredoxin glutathione reductase 0.2215 1 1
Schistosoma mansoni nephrin 0.0578 0.2237 0.2237
Echinococcus multilocularis neurogenic locus notch protein 4 0.0224 0.0554 0.0547
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0132 0.0117 0.011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0129 0.0104 0.0104
Onchocerca volvulus 0.0113 0.0029 0.0073
Echinococcus granulosus twitchin 0.0624 0.2452 0.2447
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0785 0.3216 0.3216
Plasmodium falciparum serine/threonine protein kinase KIN 0.0154 0.0224 0.0122
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0204 0.0459 0.0452
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0768 0.3134 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.1708 0.1708
Loa Loa (eye worm) SRC-1 0.0306 0.0946 0.0946
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.1805 0.1805
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0199 0.0438 0.0431
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0245 0.0654 0.0654
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.016 0.025 0.0148
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Giardia lamblia Glutamate synthase 0.0204 0.0459 0.0688
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0487 0.1805 0.1799
Brugia malayi Sex muscle abnormal protein 5 0.0123 0.0076 0.0076
Loa Loa (eye worm) AGC/PKA protein kinase 0.0224 0.0553 0.0553
Schistosoma mansoni serine/threonine-protein kinase 0.0326 0.1038 0.1038
Echinococcus granulosus c-Jun N-terminal kinases 0.0526 0.1986 0.198
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Loa Loa (eye worm) TK protein kinase 0.0373 0.1263 0.1263
Brugia malayi MAP kinase sur-1 0.0165 0.0276 0.0276
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0154 0.0224 0.0224
Entamoeba histolytica serine/threonine protein kinase, putative 0.0154 0.0224 0.0966
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni disulfide oxidoreductase 0.0204 0.0459 0.0459
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0204 0.0459 0.0452
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0485 0.1792 0.1786
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0864 0.3593 0.3588
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0243 0.0648 0.0648
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0161 0.0254 0.0254
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0299 0.0911 0.0911
Schistosoma mansoni serine/threonine protein kinase 0.095 0.4 0.4
Loa Loa (eye worm) cyclin domain-containing protein 0.0424 0.1506 0.1506
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0247 0.0663 0.0565
Echinococcus multilocularis roundabout 2 0.0263 0.074 0.0734
Brugia malayi casein kinase 1, delta 0.0215 0.0512 0.0512
Echinococcus multilocularis serine:threonine protein kinase N2 0.0578 0.2236 0.223
Plasmodium falciparum serine/threonine protein kinase 0.0164 0.027 0.0168
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0154 0.0224 0.0224
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0665 0.2647 0.2647
Echinococcus multilocularis raf serine:threonine protein kinase 0.0149 0.0198 0.0191
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0154 0.0224 0.0122
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0204 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Loa Loa (eye worm) hypothetical protein 0.0224 0.0553 0.0553
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.099 0.0983
Entamoeba histolytica protein kinase 2, putative 0.0311 0.0966 0.4272
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0263 0.074 0.0734
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0692 0.2775 0.2775
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0154 0.0224 0.0217
Echinococcus granulosus CDC7 cell division cycle 7 0.0177 0.0333 0.0326
Echinococcus granulosus protein kinase c iota type 0.0568 0.2189 0.2184
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0204 0.0459 0.0452
Giardia lamblia Kinase, AGC AKT 0.0232 0.0591 0.1148
Onchocerca volvulus 0.0413 0.1453 0.4401
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0563 0.0556
Schistosoma mansoni tyrosine kinase 0.0188 0.0385 0.0385
Echinococcus multilocularis epidermal growth factor receptor 0.0485 0.1795 0.1789
Echinococcus granulosus cyclin dependent kinase 0.0235 0.0608 0.0601
Brugia malayi Protein kinase domain containing protein 0.0602 0.2349 0.2349
Entamoeba histolytica protein kinase, putative 0.0255 0.0701 0.3092
Schistosoma mansoni hypothetical protein 0.0203 0.0458 0.0458
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0325 0.1034 0.1034
Onchocerca volvulus 0.0113 0.0029 0.0073
Loa Loa (eye worm) TK/INSR protein kinase 0.0602 0.2349 0.2349
Entamoeba histolytica protein kinase, putative 0.0233 0.0599 0.2635
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0255 0.0701 0.0701
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0309 0.0957 0.0957
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0768 0.3134 1
Toxoplasma gondii rhoptry neck protein RON9 0.0413 0.1453 0.1363
Echinococcus multilocularis protein kinase c epsilon type 0.0405 0.1416 0.141
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0702 0.2822 0.2817
Schistosoma mansoni septate junction protein 0.0224 0.0554 0.0554
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0117 0.0117
Brugia malayi p70 ribosomal S6 kinase beta 0.0566 0.2179 0.2179
Echinococcus granulosus cyclin dependent kinase 1 0.0235 0.0608 0.0601
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0232 0.0591 0.0591
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0204 0.0459 0.0359
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0198 0.0431 0.0431
Entamoeba histolytica protein kinase, putative 0.0242 0.064 0.2821
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Schistosoma mansoni hemicentin 0.0131 0.0115 0.0115
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0459 0.1671 0.1665
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Brugia malayi Cadherin domain containing protein 0.0224 0.0554 0.0554
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.016 0.0251 0.0244
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0319 0.1008 0.1001
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0305 0.0938 0.0843
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Brugia malayi Thioredoxin reductase 0.2215 1 1
Echinococcus granulosus titin 0.0113 0.0029 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0701 0.2238
Echinococcus granulosus hemicentin 1 0.0245 0.0654 0.0647
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.064 0.2526 0.2526
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0204 0.0459 0.0459
Giardia lamblia Kinase, NEK 0.027 0.0772 0.1777
Loa Loa (eye worm) AGC/NDR protein kinase 0.0319 0.1008 0.1008
Plasmodium falciparum tyrosine kinase-like protein, putative 0.016 0.025 0.0148
Echinococcus granulosus tyrosine protein kinase Src42A 0.0306 0.0946 0.0939
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Brugia malayi Protein kinase domain containing protein 0.0424 0.1502 0.1502
Schistosoma mansoni netrin receptor unc5 0.0132 0.0117 0.0117
Schistosoma mansoni ephrin receptor 0.0193 0.0408 0.0408
Schistosoma mansoni tyrosine kinase 0.0282 0.083 0.083
Echinococcus multilocularis casein kinase I delta 0.0215 0.0512 0.0505
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0178 0.0338 0.0338
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0399 0.1384 0.1377
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0305 0.0938 0.0843
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis casein kinase I alpha 0.0215 0.0512 0.0505
Trichomonas vaginalis AGC family protein kinase 0.0224 0.0553 0.1765
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0131 0.0115 0.0115
Toxoplasma gondii selenide, water dikinase 0.0204 0.0459 0.0359
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0768 0.3134 0.3134
Echinococcus multilocularis casein kinase i 0.0215 0.0512 0.0505
Schistosoma mansoni titin 0.0195 0.0417 0.0417
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0233 0.0599 0.0592
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0204 0.0459 0.0459
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Brugia malayi Protein kinase domain containing protein 0.0161 0.0254 0.0254
Brugia malayi hypothetical protein 0.0223 0.0551 0.0551
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0311 0.0966 0.0959
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0564 0.2167 0.2167
Echinococcus granulosus mitogen activated protein kinase 11 0.0316 0.099 0.0983
Schistosoma mansoni serine/threonine protein kinase 0.0785 0.3216 0.3216
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0224 0.0553 0.0454
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0204 0.0459 0.2012
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0399 0.1384 0.1377
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0165 0.0276 0.0174
Trypanosoma cruzi aurora B kinase, putative 0.0233 0.0599 0.0599
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.017 0.0297 0.029
Plasmodium falciparum calcium-dependent protein kinase 4 0.0199 0.0438 0.0337
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Leishmania major protein kinase, putative 0.0305 0.0938 0.0843
Echinococcus multilocularis calcium dependent protein kinase 0.0136 0.0135 0.0128
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Trichomonas vaginalis CMGC family protein kinase 0.0305 0.0938 0.2992
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0333 0.0333
Trichomonas vaginalis CMGC family protein kinase 0.0165 0.0276 0.0879
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Brugia malayi Protein kinase domain containing protein 0.0326 0.1037 0.1037
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus casein kinase I delta 0.0215 0.0512 0.0505
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0204 0.0459 0.2012
Brugia malayi kettin 0.0113 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0368 0.0368
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Brugia malayi hypothetical protein 0.0442 0.1587 0.1587
Loa Loa (eye worm) protein kinase domain-containing protein 0.0424 0.1502 0.1502
Loa Loa (eye worm) thioredoxin reductase 0.2215 1 1
Echinococcus multilocularis serine threonine protein kinase 0.0401 0.1395 0.1389
Plasmodium vivax serine/threonine kinase-1, putative 0.0305 0.0938 0.0706
Echinococcus multilocularis titin 0.0195 0.0417 0.041
Echinococcus granulosus titin 0.0195 0.0417 0.041
Brugia malayi Immunoglobulin I-set domain containing protein 0.0195 0.0417 0.0417
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0985 0.4165 0.4161
Schistosoma mansoni c4b-binding protein beta chain 0.0413 0.1453 0.1453
Trypanosoma cruzi polo-like protein kinase, putative 0.0538 0.2043 0.2043
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0204 0.0459 0.1464
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0487 0.1805 0.1799
Echinococcus multilocularis mitogen activated protein kinase 3 0.0165 0.0276 0.0268
Echinococcus granulosus tyrosine protein kinase Srms 0.0545 0.208 0.2074
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0228 0.0573 0.0566
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0467 0.1708 0.1702
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0108 0.0005 0.0005
Brugia malayi protein unc-22 0.0195 0.0417 0.0417
Trypanosoma brucei casein kinase I, isoform 2 0.0215 0.0512 0.0412
Entamoeba histolytica hypothetical protein 0.0242 0.064 0.2821
Giardia lamblia Kinase, AGC PKA 0.0311 0.0966 0.2453
Echinococcus granulosus cyclin dependent kinase 9 0.0116 0.0045 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Giardia lamblia Kinase, CMGC MAPK 0.0165 0.0276 0.0049
Brugia malayi Protein kinase domain containing protein 0.0164 0.027 0.027
Echinococcus granulosus dual specificity 0.0275 0.0799 0.0792
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Brugia malayi GCC2 and GCC3 family protein 0.0637 0.2515 0.2515
Giardia lamblia Kinase, CMGC SRPK 0.0164 0.027 0.0028
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0224 0.0553 0.0553
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0235 0.0608 0.0509
Loa Loa (eye worm) carbonic anhydrase 3 0.0214 0.0509 0.0509
Onchocerca volvulus 0.0125 0.0083 0.024
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0447 0.1614 0.1614
Brugia malayi protein kinase C3,putative 0.0313 0.0976 0.0976
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0452
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0215 0.0512 0.0512
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0447 0.1614 0.1614
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0165 0.0276 0.0276
Echinococcus multilocularis PAK box P21 Rho binding 0.0126 0.0092 0.0084
Schistosoma mansoni slit 0.0224 0.0557 0.0557
Plasmodium falciparum casein kinase 1 0.0215 0.0512 0.0412
Loa Loa (eye worm) Notch2 0.0224 0.0554 0.0554
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Entamoeba histolytica SH2-protein kinase domain containing protein 0.013 0.0109 0.0452
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0204 0.0459 0.0359
Brugia malayi hypothetical protein 0.0465 0.17 0.17
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0104 0.043
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0109 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase Blk 0.025 0.0676 0.0669
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0689 0.0689
Schistosoma mansoni titin 0.0131 0.0115 0.0115
Schistosoma mansoni atypical protein kinase C 0.0581 0.2247 0.2247
Schistosoma mansoni septate junction protein 0.0245 0.0654 0.0654
Loa Loa (eye worm) thyroid receptor interactor 0.0204 0.0462 0.0462
Echinococcus granulosus insulin growth factor binding 0.0113 0.0029 0.0021
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0178 0.0338 0.0331
Leishmania major protein kinase, putative 0.0167 0.0284 0.0182
Echinococcus granulosus casein kinase I alpha 0.0215 0.0512 0.0505
Echinococcus granulosus protein jagged 2 0.0224 0.0554 0.0547
Echinococcus granulosus roundabout 2 0.071 0.2862 0.2856
Echinococcus multilocularis 0.0304 0.0933 0.0926
Schistosoma mansoni protein kinase 0.0126 0.0092 0.0092
Echinococcus granulosus neurogenic locus notch protein 0.0224 0.0554 0.0547
Brugia malayi Protein kinase domain containing protein 0.0177 0.0333 0.0333
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Brugia malayi probable protein kinase 0.0527 0.1992 0.1992
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.027 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0402 0.1402 0.1402
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0224 0.0553 0.0454
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0601 0.2343 0.2343
Loa Loa (eye worm) hypothetical protein 0.0216 0.0518 0.0518
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0223 0.0551 0.0544
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0526 0.1986 0.1986
Plasmodium falciparum protein serine/threonine kinase-1 0.0305 0.0938 0.0843
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) hypothetical protein 0.0374 0.1268 0.1268
Trypanosoma cruzi casein kinase II, putative 0.0198 0.0431 0.0431
Echinococcus multilocularis casein kinase I gamma 0.0424 0.1502 0.1496
Schistosoma mansoni nephrin related 0.0132 0.0117 0.0117
Echinococcus granulosus Protein kinase C brain isozyme 0.0485 0.1792 0.1786
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Entamoeba histolytica thioredoxin reductase, putative 0.0204 0.0459 0.2012
Echinococcus multilocularis c4b binding protein beta chain 0.0413 0.1453 0.1447
Echinococcus granulosus serine:threonine protein kinase 0.0226 0.0563 0.0556
Schistosoma mansoni laminin gamma-3 chain 0.0224 0.0554 0.0554
Onchocerca volvulus 0.0114 0.0031 0.0081
Loa Loa (eye worm) RhoGAP domain-containing protein 0.015 0.0203 0.0203
Onchocerca volvulus Serine\/threonine kinase homolog 0.0538 0.2043 0.6192
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.099 0.099
Plasmodium falciparum casein kinase 2, alpha subunit 0.0198 0.0431 0.033
Brugia malayi pregnancy-associated plasma protein-A 0.0413 0.1453 0.1453
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0255 0.0701 0.0694
Schistosoma mansoni tyrosine kinase 0.0188 0.0385 0.0385
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0204 0.0459 0.0359
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0526 0.1986 0.198
Trypanosoma cruzi polo-like protein kinase, putative 0.0538 0.2043 0.2043
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0235 0.0608 0.0601
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0359
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Echinococcus multilocularis epidermal growth factor receptor 0.0697 0.2798 0.2792
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0165 0.0276 0.0276
Brugia malayi Protein kinase domain containing protein 0.0242 0.064 0.064
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0167 0.0284 0.0182
Onchocerca volvulus 0.0113 0.0029 0.0073
Onchocerca volvulus 0.0583 0.226 0.6853
Plasmodium falciparum NIMA related kinase 1 0.027 0.0772 0.0675
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0538 0.2043 0.2037
Trypanosoma brucei cdc2-related kinase 3 0.0235 0.0608 0.0509
Echinococcus multilocularis calcium activated potassium channel 0.0267 0.076 0.0753
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0893 0.3731 0.3731
Echinococcus multilocularis hypothetical protein 0.0203 0.0458 0.0451
Onchocerca volvulus Slit protein homolog 0.0268 0.0765 0.231
Brugia malayi Doublecortin family protein 0.0299 0.0911 0.0911
Echinococcus granulosus carbonic anhydrase II 0.0214 0.0509 0.0502
Echinococcus granulosus ephrin type A receptor 4 A 0.0193 0.0408 0.0401
Schistosoma mansoni vesicular amine transporter 0.0447 0.1614 0.1614
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0204 0.0459 0.0215
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.064 0.064
Echinococcus granulosus serine:threonine protein kinase 3 0.0511 0.1915 0.1909
Schistosoma mansoni ste20-related kinase 0.0407 0.1425 0.1425
Echinococcus granulosus protein kinase c epsilon type 0.0405 0.1416 0.141
Trypanosoma brucei trypanothione reductase 0.2215 1 1
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0132 0.0117 0.011
Brugia malayi Peroxidasin 0.0245 0.0656 0.0656
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.015 0.0204 0.0197
Loa Loa (eye worm) programmed cell death 8 0.0204 0.0459 0.0459
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0164 0.027 0.0168
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Plasmodium falciparum calcium-dependent protein kinase 2 0.0199 0.0438 0.0337
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0199 0.0438 0.0337
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3134
Echinococcus multilocularis casein kinase I delta 0.0215 0.0512 0.0505
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0204 0.0459 0.0359
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Loa Loa (eye worm) disorganized muscle protein 1 0.0113 0.0029 0.0029
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Echinococcus multilocularis c src tyrosine kinase 0.0188 0.0385 0.0378
Loa Loa (eye worm) hypothetical protein 0.0226 0.0563 0.0563
Trypanosoma cruzi cdc2-related kinase 3 0.0235 0.0608 0.0608
Schistosoma mansoni hypothetical protein 0.0204 0.0459 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Toxoplasma gondii histone kinase SNF1, putative 0.0154 0.0224 0.0122
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Entamoeba histolytica protein kinase, putative 0.0202 0.045 0.1971
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0204 0.0459 0.0459
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0168 0.0291 0.0291
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0165 0.0276 0.0276
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.064 0.2526 0.2526
Schistosoma mansoni tyrosine kinase 0.0404 0.1411 0.1411
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.1986 0.1986
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Echinococcus granulosus contactin 0.0263 0.074 0.0734
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0702 0.2822 0.2822
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0316 0.099 0.099
Echinococcus multilocularis serine:threonine protein kinase 0.0226 0.0563 0.0556
Schistosoma mansoni roundabout 0.0245 0.0654 0.0654
Giardia lamblia Kinase, CMGC CLK 0.0305 0.0938 0.2355
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0199 0.0438 0.0438
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.0553 0.0553
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Echinococcus granulosus neuroglian 0.056 0.215 0.2144
Trypanosoma brucei protein kinase, putative 0.0255 0.0701 0.0604
Schistosoma mansoni protein kinase 0.0233 0.0599 0.0599
Loa Loa (eye worm) TK/FER protein kinase 0.0131 0.0116 0.0116
Entamoeba histolytica serine/threonine protein kinase, putative 0.0538 0.2043 0.907
Brugia malayi Protein kinase domain containing protein 0.0893 0.3731 0.3731
Giardia lamblia Kinase, CMGC CDK 0.0235 0.0608 0.1206
Loa Loa (eye worm) TK protein kinase 0.0477 0.1754 0.1754
Entamoeba histolytica protein kinase, putative 0.017 0.0297 0.1291
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0306 0.0946 0.0939
Trichomonas vaginalis CMGC family protein kinase 0.0275 0.0799 0.2549
Echinococcus multilocularis titin 0.0113 0.0029 0.0021
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0316 0.099 0.0895
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0113 0.0029 0.0021
Echinococcus granulosus slit 2 protein 0.0268 0.0765 0.0758
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0326 0.1037 0.103
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0204 0.0459 0.0359
Entamoeba histolytica protein kinase, putative 0.0199 0.0438 0.1917
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0255 0.0701 0.0694
Echinococcus granulosus protein jagged 2 0.0224 0.0554 0.0547
Echinococcus granulosus lachesin 0.0245 0.0654 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0768 0.3134 1
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0162 0.0261 0.0012
Schistosoma mansoni tyrosine kinase 0.0128 0.0099 0.0099
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0768 0.3134 1
Brugia malayi serine/threonine kinase 12 0.0233 0.0599 0.0599
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0255 0.0701 0.0604
Trypanosoma brucei SNF1-related protein kinases, putative 0.0154 0.0224 0.0122
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Echinococcus multilocularis slit 2 protein 0.0268 0.0765 0.0758
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Brugia malayi Sushi domain 0.0413 0.1453 0.1453
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0204 0.0459 0.0459
Brugia malayi SRC-1 0.0306 0.0946 0.0946
Onchocerca volvulus 0.0623 0.245 0.7431
Echinococcus granulosus casein kinase i 0.0215 0.0512 0.0505
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Echinococcus multilocularis netrin receptor unc 5 0.0189 0.0391 0.0384
Plasmodium falciparum glycogen synthase kinase 3 0.0255 0.0701 0.0604
Echinococcus multilocularis tyrosine protein kinase shark 0.0348 0.1144 0.1138
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.1416 0.1416
Loa Loa (eye worm) hypothetical protein 0.0132 0.0117 0.0117
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0224 0.0553 0.0553
Schistosoma mansoni neuroglian 0.0263 0.074 0.074
Plasmodium vivax unspecified product 0.0198 0.0431 0.0186
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0203 0.0458 0.0458
Trypanosoma brucei protein kinase, putative 0.0173 0.0313 0.0211
Brugia malayi protein kinase C II. 0.0405 0.1416 0.1416
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0204 0.0459 0.1464
Plasmodium vivax thioredoxin reductase, putative 0.2215 1 1
Schistosoma mansoni nephrin 0.0263 0.074 0.074
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0242 0.064 0.0542
Schistosoma mansoni cell adhesion molecule 0.0263 0.074 0.074
Trichomonas vaginalis AGC family protein kinase 0.0161 0.0254 0.0811
Echinococcus multilocularis notch 0.0224 0.0554 0.0547
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0151 0.0209 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0647 0.2562 0.2562
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0235 0.0608 0.0608
Echinococcus multilocularis hemicentin 1 0.0245 0.0654 0.0647
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.017 0.0297 0.029
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.015 0.0203 0.0203
Schistosoma mansoni protein kinase 0.0864 0.3593 0.3593
Trypanosoma cruzi Protein kinase B 0.0326 0.1038 0.1038
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0364 0.1218 0.1212
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0224 0.0553 0.0546
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0326 0.1038 0.1038
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Trichomonas vaginalis CMGC family protein kinase 0.0235 0.0608 0.1939
Schistosoma mansoni sulfide quinone reductase 0.0204 0.0459 0.0459
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.073 0.2956 0.2951
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0242 0.064 0.064
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0768 0.3134 1
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0223 0.0551 0.0544
Loa Loa (eye worm) hypothetical protein 0.0374 0.1268 0.1268
Echinococcus granulosus roundabout 2 0.0263 0.074 0.0734
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0199 0.0438 0.0431
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0132 0.0117 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0281 0.0827 0.0827
Trichomonas vaginalis CK1 family protein kinase 0.0215 0.0512 0.1633
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0326 0.1037 0.103
Loa Loa (eye worm) AUR protein kinase 0.0233 0.0599 0.0599
Echinococcus granulosus cyclin 0.0424 0.1506 0.15
Onchocerca volvulus 0.0131 0.0116 0.0338
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0319 0.1008 0.1001
Brugia malayi serine/threonine-protein kinase 6 0.0233 0.0599 0.0599
Schistosoma mansoni cell adhesion molecule 0.0245 0.0654 0.0654
Toxoplasma gondii EGF family domain-containing protein 0.0224 0.0554 0.0455
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0305 0.0938 0.0938
Trypanosoma cruzi cdc2-related kinase 3 0.0235 0.0608 0.0608
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.064 0.2821
Brugia malayi Protein kinase domain containing protein 0.0226 0.0563 0.0563
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0132 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Onchocerca volvulus 0.0131 0.0116 0.0338
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0154 0.0224 0.0122
Brugia malayi Disorganized muscle protein 1 0.0113 0.0029 0.0029
Echinococcus multilocularis growth factor receptor bound protein 2 0.0123 0.0076 0.0069
Schistosoma mansoni serine/threonine kinase 0.0319 0.1008 0.1008
Brugia malayi Tyrosine-protein kinase abl-1 0.0188 0.0385 0.0385
Echinococcus multilocularis Immunoglobulin subtype 0.0132 0.0117 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0198 0.0431 0.1374
Giardia lamblia Aurora kinase 0.0233 0.0599 0.1174
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0263 0.074 0.0734
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0463 0.1689 0.1683
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0461 0.1681 0.1681
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0431 0.1538 0.1538
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.073 0.2956 0.2956
Loa Loa (eye worm) TK protein kinase 0.0309 0.0957 0.0957
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Schistosoma mansoni notch 0.0224 0.0554 0.0554
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0252 0.0689 0.0689
Echinococcus multilocularis protein jagged 1 0.0224 0.0554 0.0547
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Brugia malayi STE20-like kinase MST 0.0511 0.1915 0.1915
Brugia malayi P38 map kinase family protein 2 0.0316 0.099 0.099
Brugia malayi Protein kinase domain containing protein 0.0121 0.0068 0.0068
Brugia malayi Immunoglobulin domain containing protein 0.0132 0.0117 0.0117
Echinococcus multilocularis mitogen activated protein kinase 14 0.0316 0.099 0.0983
Schistosoma mansoni tyrosine kinase 0.0364 0.1218 0.1218
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0029 0.0029
Brugia malayi Prion-like- 0.0113 0.0029 0.0029
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0245 0.0654 0.0647
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Loa Loa (eye worm) hypothetical protein 0.0384 0.1313 0.1313
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0438 0.0438
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3134
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0402 0.1402 0.1395
Schistosoma mansoni serine/threonine protein kinase 0.0578 0.2236 0.2236
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3062
Brugia malayi EGF-like domain containing protein 0.0224 0.0554 0.0554
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0247 0.0664 0.0657
Echinococcus multilocularis NCK adaptor protein 0.0125 0.0086 0.0079
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0204 0.0459 0.0459
Brugia malayi Cyclin, N-terminal domain containing protein 0.0424 0.1506 0.1506
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.2043 0.2043
Trichomonas vaginalis AGC family protein kinase 0.0582 0.2251 0.7184
Echinococcus granulosus growth factor receptor bound protein 2 0.0125 0.0086 0.0079
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0364 0.1218 0.1212
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0132 0.0117 0.0117
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0702 0.2822 0.2822
Echinococcus multilocularis 0.0241 0.0636 0.0629
Echinococcus multilocularis protein jagged 1 0.0224 0.0554 0.0547
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Brugia malayi protein-tyrosine kinase 0.025 0.0676 0.0676
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0306 0.0946 0.0939
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Plasmodium falciparum cGMP-dependent protein kinase 0.0167 0.0284 0.0182
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0768 0.3134 0.2958
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0275 0.0799 0.0799
Echinococcus multilocularis nervana 2 0.0247 0.0664 0.0657
Brugia malayi Temporarily assigned gene name protein 59 0.0258 0.0714 0.0714
Brugia malayi Protein kinase domain containing protein 0.0585 0.2269 0.2269
Loa Loa (eye worm) hypothetical protein 0.0597 0.2322 0.2322
Loa Loa (eye worm) hypothetical protein 0.0361 0.1203 0.1203
Echinococcus multilocularis aurora kinase A 0.0233 0.0599 0.0592
Onchocerca volvulus 0.0195 0.0417 0.1255
Plasmodium falciparum glutathione reductase 0.0768 0.3134 0.3062
Brugia malayi Prion-like- 0.0245 0.0654 0.0654
Echinococcus granulosus tyrosine protein kinase shark 0.0348 0.1144 0.1138
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0115 0.0115
Trypanosoma cruzi casein kinase, putative 0.0215 0.0512 0.0512
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0132 0.0117 0.011
Entamoeba histolytica protein kinase domain containing protein 0.0198 0.0431 0.1887
Loa Loa (eye worm) hypothetical protein 0.0465 0.17 0.17
Echinococcus granulosus activin receptor type 0.0129 0.0104 0.0096
Schistosoma mansoni protein kinase 0.073 0.2956 0.2956
Echinococcus granulosus tyrosine protein kinase Fps85D 0.044 0.1578 0.1571
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Onchocerca volvulus Peroxidasin homolog 0.0114 0.0031 0.0081
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0113 0.0029 0.0029
Loa Loa (eye worm) TK protein kinase 0.025 0.0676 0.0676
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0204 0.0459 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0768 0.3134 0.2803
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0326 0.1037 0.1037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0768 0.3134 0.3134
Brugia malayi glutamate synthase 0.0204 0.0459 0.0459
Entamoeba histolytica cyclin C, putative 0.0431 0.1535 0.6808
Leishmania major protein kinase A catalytic subunit isoform 2 0.0224 0.0553 0.0454
Echinococcus granulosus serine:threonine protein kinase N2 0.0578 0.2236 0.223
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase HCK 0.0183 0.0362 0.0355
Entamoeba histolytica PH domain containing protein kinase, putative 0.0326 0.1038 0.4593
Trichomonas vaginalis STE family protein kinase 0.0126 0.0092 0.0293
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0165 0.0276 0.0174
Brugia malayi Stress-activated protein kinase jnk-1 0.0526 0.1986 0.1986
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0564 0.2167 0.2167
Onchocerca volvulus Tyrosine kinase homolog 0.0802 0.3296 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0768 0.3134 1
Onchocerca volvulus Netrin receptor homolog 0.0171 0.0303 0.0905
Loa Loa (eye worm) hypothetical protein 0.0447 0.1614 0.1614
Echinococcus granulosus cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Schistosoma mansoni protein kinase 0.0439 0.1577 0.1577
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0768 0.3134 0.3062
Echinococcus granulosus leucine rich repeat containing protein 4 0.0113 0.0029 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.0538 0.2043 0.6518
Schistosoma mansoni kinase 0.0574 0.2217 0.2217
Brugia malayi Kinase associated domain 1 family protein 0.0203 0.0458 0.0458
Echinococcus granulosus down syndrome cell adhesion 0.0113 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0245 0.0656 0.0656
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0768 0.3134 0.3062
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Brugia malayi Protein kinase domain containing protein 0.064 0.2526 0.2526
Schistosoma mansoni titin 0.0245 0.0654 0.0654
Plasmodium falciparum ferrodoxin reductase-like protein 0.0204 0.0459 0.0359
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0864 0.3593 0.3588
Loa Loa (eye worm) hypothetical protein 0.0285 0.0845 0.0845
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0277 0.0804 0.2566
Brugia malayi serine/threonine-protein kinase PAK 7 0.0461 0.1681 0.1681
Schistosoma mansoni serine/threonine protein kinase 0.0507 0.1898 0.1898
Leishmania major hypothetical protein, conserved 0.0204 0.0459 0.0359
Brugia malayi Myb-like DNA-binding domain containing protein 0.0113 0.0029 0.0029
Giardia lamblia Kinase, STE STE20 0.0167 0.0284 0.0079
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0123 0.0076 0.0076
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0429 0.1528 0.1522
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0938 0.0938
Onchocerca volvulus Peroxidasin homolog 0.0113 0.0029 0.0073
Echinococcus multilocularis neurogenic locus protein delta 0.0224 0.0554 0.0547
Echinococcus granulosus tyrosine protein kinase otk 0.0245 0.0654 0.0647
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0214 0.0509 0.0509
Loa Loa (eye worm) hypothetical protein 0.0255 0.0702 0.0702
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0215 0.0512 0.0512
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0447 0.1614 0.1608
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Loa Loa (eye worm) AGC/PKN protein kinase 0.0578 0.2236 0.2236
Loa Loa (eye worm) hypothetical protein 0.0637 0.2515 0.2515
Echinococcus multilocularis Immunoglobulin 0.0447 0.1614 0.1608
Giardia lamblia Kinase, CMGC CK2 0.0198 0.0431 0.0589
Brugia malayi Immunoglobulin I-set domain containing protein 0.0477 0.1754 0.1754
Echinococcus multilocularis 0.0113 0.0029 0.0021
Echinococcus granulosus nervana 2 0.0247 0.0664 0.0657
Entamoeba histolytica protein kinase, putative 0.0242 0.064 0.2821
Brugia malayi cyclin-dependent kinase 9 0.0109 0.0007 0.0007
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0199 0.0438 0.0438
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0305 0.0938 0.0938
Loa Loa (eye worm) hypothetical protein 0.0579 0.2239 0.2239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0117 0.0117
Brugia malayi putative serine/threonine kinase SADA gamma 0.0154 0.0224 0.0224
Echinococcus granulosus notch 0.0224 0.0554 0.0547
Schistosoma mansoni basigin related 0.0132 0.0117 0.0117
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0113 0.0029 0.0021
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Protein kinase domain containing protein 0.0305 0.0938 0.0938
Onchocerca volvulus 0.0413 0.1453 0.4401
Onchocerca volvulus 0.0384 0.1313 0.3977
Entamoeba histolytica protein kinase domain containing protein 0.0255 0.0701 0.3092
Leishmania major casein kinase II, putative 0.0198 0.0431 0.033
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0164 0.027 0.027
Echinococcus granulosus serine:threonine protein kinase N2 0.0259 0.0721 0.0714
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0233 0.0599 0.2635
Onchocerca volvulus 0.0413 0.1453 0.4401
Brugia malayi Protein kinase domain containing protein 0.073 0.2956 0.2956
Echinococcus multilocularis ephrin type A receptor 4 A 0.0193 0.0408 0.0401
Plasmodium falciparum calcium-dependent protein kinase 5 0.0199 0.0438 0.0337
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0214 0.0509 0.0509
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus granulosus epidermal growth factor receptor 0.0485 0.1795 0.1789
Plasmodium falciparum protein kinase 5 0.0235 0.0608 0.0509
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0665 0.2647 0.2647
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Schistosoma mansoni titin 0.0113 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0275 0.0799 0.3527
Schistosoma mansoni hypothetical protein 0.0113 0.0029 0.0029
Brugia malayi Furin-like cysteine rich region family protein 0.0697 0.2798 0.2798
Trichomonas vaginalis glutathione reductase, putative 0.0768 0.3134 1
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Brugia malayi Protein kinase domain containing protein 0.0131 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0154 0.0224 0.0715
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0551 0.0551
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0199 0.0438 0.0438
Plasmodium vivax glycogen synthase kinase 3, putative 0.0255 0.0701 0.0463
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0115 0.0115
Entamoeba histolytica protein kinase, putative 0.0183 0.0362 0.158
Echinococcus multilocularis rho associated protein kinase 0.0647 0.2562 0.2557
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0131 0.0116 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0938 0.0938
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0132 0.0117 0.0117
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0233 0.0599 0.2635
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0164 0.027 0.0168
Echinococcus granulosus fibropellin Ia 0.0224 0.0554 0.0547
Trypanosoma cruzi hypothetical protein, conserved 0.0204 0.0459 0.0459
Schistosoma mansoni tyrosine kinase 0.0348 0.1144 0.1144
Plasmodium falciparum thioredoxin reductase 0.2215 1 1
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0275 0.0799 0.0702
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.1037 0.1037
Echinococcus granulosus tyrosine protein kinase ABL1 0.0131 0.0116 0.0109
Brugia malayi hypothetical protein 0.0413 0.1453 0.1453
Echinococcus granulosus neurogenic locus notch protein 4 0.0224 0.0554 0.0547
Entamoeba histolytica PH domain containing protein kinase, putative 0.0239 0.0625 0.2752
Echinococcus multilocularis peroxidasin 0.0245 0.0656 0.0649
Trichomonas vaginalis CMGC family protein kinase 0.0177 0.0333 0.1062
Schistosoma mansoni sulfide quinone reductase 0.0204 0.0459 0.0459
Treponema pallidum NADH oxidase 0.0768 0.3134 1
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0311 0.0966 0.0871
Toxoplasma gondii CMGC kinase, CK2 family 0.0198 0.0431 0.033
Schistosoma mansoni cell adhesion molecule 0.0597 0.2325 0.2325
Brugia malayi SH2 domain containing protein 0.0131 0.0116 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0167 0.0284 0.0277
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0224 0.0553 0.0454
Echinococcus granulosus neurogenic locus notch protein 0.0224 0.0554 0.0547
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0319 0.1008 0.1001
Loa Loa (eye worm) hypothetical protein 0.0224 0.0554 0.0554
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0204 0.0459 0.0452
Onchocerca volvulus 0.0113 0.0029 0.0073
Giardia lamblia NADH oxidase lateral transfer candidate 0.0768 0.3134 1
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.076 0.076
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0485 0.1795 0.1789
Trichomonas vaginalis glutamate synthase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni serine/threonine protein kinase 0.0429 0.1528 0.1528
Echinococcus granulosus tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464
Schistosoma mansoni hypothetical protein 0.0224 0.0554 0.0554
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0305 0.0938 0.0938
Echinococcus multilocularis protein kinase c iota type 0.0568 0.2189 0.2184
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.0654 0.0654
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0255 0.0701 0.0701
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.015 0.0203 0.0196
Onchocerca volvulus 0.0413 0.1453 0.4401
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Loa Loa (eye worm) hypothetical protein 0.0413 0.1453 0.1453
Brugia malayi hypothetical protein 0.0132 0.0117 0.0117
Schistosoma mansoni serine/threonine protein kinase 0.0424 0.1502 0.1502
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0204 0.0459 0.0215
Echinococcus multilocularis neurogenic locus notch protein 0.0224 0.0554 0.0547
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0198 0.0431 0.0186
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0131 0.0116 0.0483
Loa Loa (eye worm) hypothetical protein 0.0223 0.0551 0.0551
Schistosoma mansoni netrin receptor unc5 0.0189 0.0391 0.0391
Schistosoma mansoni tyrosine kinase 0.042 0.1486 0.1486
Echinococcus multilocularis casein kinase ii subunit alpha 0.0198 0.0431 0.0424
Echinococcus multilocularis carbonic anhydrase II 0.0214 0.0509 0.0502
Trichomonas vaginalis CAMK family protein kinase 0.0431 0.1538 0.4907
Echinococcus granulosus hypothetical protein 0.0241 0.0636 0.0629
Entamoeba histolytica protein kinase, putative 0.0141 0.0164 0.0696
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.017 0.0297 0.029
Schistosoma mansoni myosin-binding protein-related 0.0131 0.0115 0.0115
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0538 0.2043 0.2043
Schistosoma mansoni cell polarity protein 0.0224 0.0554 0.0554
Trypanosoma brucei carbonic anhydrase-like protein 0.0214 0.0509 0.041
Brugia malayi basement membrane proteoglycan precursor 0.0132 0.0117 0.0117
Onchocerca volvulus 0.0224 0.0554 0.167
Trypanosoma cruzi cdc2-related kinase 1 0.0235 0.0608 0.0608
Schistosoma mansoni hypothetical protein 0.0203 0.0458 0.0458
Schistosoma mansoni vav2 0.0165 0.0275 0.0275
Brugia malayi Fes/CIP4 homology domain containing protein 0.0204 0.0462 0.0462
Echinococcus granulosus insulin receptor 0.0602 0.2349 0.2343
Trypanosoma brucei hypothetical protein, conserved 0.0204 0.0459 0.0359
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0442 0.1587 0.1581
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.015 0.0204 0.0204
Brugia malayi phosphoinositide-dependent protein kinase I 0.0161 0.0254 0.0254
Echinococcus granulosus netrin receptor unc 5 0.0189 0.0391 0.0384
Schistosoma mansoni protein kinase 0.017 0.0297 0.0297
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0799 0.0799
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0242 0.064 0.064
Brugia malayi Protein kinase domain containing protein 0.0305 0.0941 0.0941
Echinococcus multilocularis neurogenic locus protein delta 0.0224 0.0554 0.0547
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0306 0.0946 0.0939
Loa Loa (eye worm) hypothetical protein 0.0113 0.0029 0.0029
Echinococcus multilocularis expressed conserved protein 0.0167 0.0284 0.0277
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.025 0.0676 0.0669
Giardia lamblia Kinase, STE STE20 0.017 0.0297 0.0124
Trichomonas vaginalis STE family protein kinase 0.017 0.0297 0.0948
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.1792 0.1792
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0553 0.0553
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0204 0.0459 0.1464

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 35 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 35 nM Inhibitory activity against Carbonic anhydrase IX ChEMBL. 15771455
Ki (binding) = 67 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 67 nM Inhibitory activity against Carbonic anhydrase II ChEMBL. 15771455
Ki (binding) = 1250 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455
Ki (binding) = 1250 nM Inhibitory activity against Carbonic anhydrase I ChEMBL. 15771455

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.