Detailed information for compound 313456

Basic information

Technical information
  • TDR Targets ID: 313456
  • Name: N,N-dimethyl-4-[(E)-2-naphthalen-2-ylethenyl] aniline
  • MW: 273.372 | Formula: C20H19N
  • H donors: 0 H acceptors: 0 LogP: 5.56 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ccc(cc1)/C=C/c1ccc2c(c1)cccc2)C
  • InChi: 1S/C20H19N/c1-21(2)20-13-10-16(11-14-20)7-8-17-9-12-18-5-3-4-6-19(18)15-17/h3-15H,1-2H3/b8-7+
  • InChiKey: RRDADBSXDJUDCW-BQYQJAHWSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N,N-dimethyl-4-[(E)-2-(2-naphthyl)vinyl]aniline
  • N,N-dimethyl-4-[(E)-2-(2-naphthalenyl)vinyl]aniline
  • dimethyl-[4-[(E)-2-(2-naphthyl)vinyl]phenyl]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Echinococcus granulosus casein kinase ii subunit alpha 0.0223 0.0234 0.0234
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.031 0.0469 0.0469
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0174 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Entamoeba histolytica protein kinase, putative 0.0359 0.0603 0.33
Echinococcus granulosus casein kinase I delta 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.103 0.2425 0.2425
Echinococcus granulosus NDR protein kinase 0.0359 0.0603 0.0603
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0452 0.1359
Loa Loa (eye worm) hypothetical protein 0.0174 0.0101 0.0101
Schistosoma mansoni growth factor receptor-bound protein 0.0139 0.0006 0.0006
Echinococcus multilocularis neurogenic locus notch protein 4 0.0418 0.0763 0.0763
Schistosoma mansoni cell adhesion molecule 0.0212 0.0203 0.0203
Leishmania major protein kinase, putative 0.0189 0.014 0.0116
Brugia malayi Sushi domain 0.0713 0.1563 0.1563
Brugia malayi Cam kinase protein 1 0.0225 0.0238 0.0238
Brugia malayi SH2 domain containing protein 0.0489 0.0955 0.0955
Brugia malayi Myb-like DNA-binding domain containing protein 0.0177 0.0108 0.0108
Onchocerca volvulus 0.031 0.0469 0.2092
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0351 0.0581 0.0581
Trichomonas vaginalis CMGC family protein kinase 0.0343 0.0558 0.169
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0249 0.0305 0.0282
Echinococcus granulosus dual specificity 0.031 0.0469 0.0469
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1323 0.3222 0.3205
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0265 0.0347 0.0347
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0167 0.0081 0.0081
Echinococcus granulosus contactin 0.0409 0.0739 0.0739
Brugia malayi Stress-activated protein kinase jnk-1 0.059 0.1229 0.1229
Echinococcus multilocularis cyclin dependent kinase 9 0.0169 0.0086 0.0086
Loa Loa (eye worm) CAMK protein kinase 0.0271 0.0362 0.0362
Echinococcus multilocularis expressed protein 0.0185 0.0131 0.0131
Schistosoma mansoni tyrosine kinase 0.0671 0.145 0.145
Plasmodium falciparum glycogen synthase kinase 3 0.0287 0.0407 0.0384
Entamoeba histolytica protein kinase, putative 0.016 0.0063 0.0259
Schistosoma mansoni protein kinase C mu 0.0486 0.0946 0.0946
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0249 0.0305 0.0282
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0283 0.0397 0.0397
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Echinococcus granulosus serine:threonine protein kinase N2 0.0649 0.1389 0.1389
Schistosoma mansoni hypothetical protein 0.0249 0.0305 0.0305
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0252 0.0312 0.0289
Entamoeba histolytica hypothetical protein 0.0273 0.0368 0.1977
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Plasmodium vivax serine/threonine kinase-1, putative 0.0343 0.0558 0.0446
Echinococcus granulosus Immunoglobulin subtype 0.0212 0.0203 0.0203
Onchocerca volvulus 0.0418 0.0763 0.3435
Loa Loa (eye worm) hypothetical protein 0.025 0.0306 0.0306
Schistosoma mansoni serine/threonine protein kinase 0.0649 0.1389 0.1389
Echinococcus granulosus cyclin 0.0786 0.1763 0.1763
Echinococcus multilocularis roundabout 2 0.0409 0.0739 0.0739
Schistosoma mansoni serine/threonine kinase 0.0359 0.0603 0.0603
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1323 0.3222 0.2803
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Brugia malayi Casein kinase II, alpha chain 0.0223 0.0234 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0187 0.0187
Echinococcus multilocularis activin receptor type 0.0146 0.0024 0.0024
Echinococcus multilocularis notch 0.0418 0.0763 0.0763
Schistosoma mansoni nephrin related 0.0212 0.0203 0.0203
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0489 0.0955 0.0955
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0307 0.0307
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0304 0.0452 0.0338
Loa Loa (eye worm) hypothetical protein 0.0249 0.0305 0.0305
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.031 0.0469 0.0447
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Onchocerca volvulus Netrin receptor homolog 0.0241 0.0283 0.1244
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0409 0.0739 0.0739
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Schistosoma mansoni cell adhesion molecule 0.0389 0.0683 0.0683
Entamoeba histolytica protein kinase, putative 0.0185 0.0131 0.0641
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0406 0.073 0.073
Brugia malayi Disorganized muscle protein 1 0.0177 0.0108 0.0108
Giardia lamblia NADH oxidase lateral transfer candidate 0.1323 0.3222 1
Schistosoma mansoni cell adhesion molecule 0.0197 0.0163 0.0163
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0146 0.0025 0.0046
Leishmania major NADH dehydrogenase, putative 0.0351 0.0581 0.0559
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.0844 0.0844
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0698 0.1523 0.1523
Giardia lamblia Kinase, NEK 0.0304 0.0452 0.104
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0603 0.0603
Loa Loa (eye worm) TK/EGFR protein kinase 0.0775 0.1733 0.1733
Loa Loa (eye worm) hypothetical protein 0.0718 0.1578 0.1578
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0359 0.0603 0.0603
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.168 0.4189 0.4189
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0368 0.0368
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0819 0.1851 0.1851
Plasmodium falciparum calcium-dependent protein kinase 4 0.0225 0.0238 0.0215
Brugia malayi Immunoglobulin I-set domain containing protein 0.0409 0.0739 0.0739
Toxoplasma gondii rhoptry neck protein RON1 0.0713 0.1563 0.1542
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1323 0.3222 0.3205
Echinococcus granulosus lachesin 0.0389 0.0683 0.0683
Schistosoma mansoni hypothetical protein 0.0351 0.0581 0.0581
Brugia malayi Thioredoxin reductase 0.3819 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Brugia malayi phosphoinositide-dependent protein kinase I 0.0182 0.0121 0.0121
Loa Loa (eye worm) TK/ROR protein kinase 0.0499 0.0984 0.0984
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0212 0.0203 0.0203
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0351 0.0581 0.0559
Plasmodium falciparum serine/threonine protein kinase, putative 0.0262 0.034 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0382 0.0666 0.2025
Brugia malayi Protein kinase domain containing protein 0.0343 0.056 0.056
Plasmodium falciparum calcium-dependent protein kinase 5 0.0225 0.0238 0.0215
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0178 0.011 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1217
Toxoplasma gondii aurora kinase 0.0262 0.034 0.0317
Echinococcus multilocularis c4b binding protein beta chain 0.0713 0.1563 0.1563
Echinococcus multilocularis casein kinase I alpha 0.0242 0.0286 0.0286
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0323 0.0504 0.0504
Trichomonas vaginalis CMGC family protein kinase 0.02 0.0171 0.0481
Echinococcus granulosus mitogen activated protein kinase 3 0.0187 0.0135 0.0135
Brugia malayi Calcium binding EGF domain containing protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) casein kinase 0.0402 0.072 0.072
Brugia malayi P38 map kinase family protein 2 0.0355 0.0592 0.0592
Echinococcus granulosus Immunoglobulin 0.0212 0.0203 0.0203
Trypanosoma cruzi casein kinase II, putative 0.0223 0.0234 0.021
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Brugia malayi Protein kinase domain containing protein 0.1066 0.2524 0.2524
Brugia malayi protein unc-22 0.0271 0.0362 0.0362
Loa Loa (eye worm) thyroid receptor interactor 0.0228 0.0247 0.0247
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0452 0.0855 0.0855
Schistosoma mansoni netrin receptor unc5 0.0212 0.0203 0.0203
Brugia malayi hypothetical protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Leishmania major protein kinase, putative 0.0343 0.0558 0.0536
Echinococcus multilocularis casein kinase I delta 0.0242 0.0286 0.0286
Brugia malayi basement membrane proteoglycan 0.0212 0.0203 0.0203
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0787 0.1765 0.1765
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0341 0.0555 0.0555
Brugia malayi serine/threonine-protein kinase 6 0.0262 0.034 0.034
Onchocerca volvulus Putative titin 0.0177 0.0108 0.0442
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Echinococcus multilocularis serine threonine protein kinase 0.0451 0.0851 0.0851
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0252 0.0312 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trypanosoma cruzi cdc2-related kinase 3 0.0265 0.0347 0.0324
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0389 0.0683 0.3073
Echinococcus multilocularis protein kinase c iota type 0.0638 0.1359 0.1359
Brugia malayi Prion-like- 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.0362 0.0362
Plasmodium falciparum glutathione reductase 0.3819 1 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.091 0.2098 0.2098
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Leishmania major hypothetical protein, conserved 0.0351 0.0581 0.0559
Echinococcus granulosus protein jagged 2 0.0418 0.0763 0.0763
Giardia lamblia Kinase, CMGC GSK 0.0287 0.0407 0.0894
Entamoeba histolytica cell division protein kinase 2, putative 0.0282 0.0393 0.2115
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0744 0.1647 0.1647
Onchocerca volvulus 0.0146 0.0025 0.0063
Plasmodium falciparum thioredoxin reductase 0.3819 1 1
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Echinococcus multilocularis roundabout 2 0.1107 0.2634 0.2634
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) AGC/AKT protein kinase 0.0652 0.1399 0.1399
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0558 0.0558
Brugia malayi GCC2 and GCC3 family protein 0.1131 0.2698 0.2698
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0359 0.0603 0.0603
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1066 0.2524 0.2524
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0351 0.0581 0.0581
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0287 0.0407 0.0407
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1323 0.3222 1
Brugia malayi Protein kinase domain containing protein 0.0713 0.1565 0.1565
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0271 0.0362 0.0362
Brugia malayi Doublecortin family protein 0.0336 0.0541 0.0541
Toxoplasma gondii rhoptry neck protein RON9 0.0713 0.1563 0.1542
Giardia lamblia Kinase, CMGC GSK 0.0287 0.0407 0.0894
Echinococcus granulosus activin receptor type 0.0146 0.0024 0.0024
Echinococcus multilocularis mitogen activated protein kinase 14 0.0355 0.0592 0.0592
Trypanosoma brucei casein kinase I, isoform 2 0.0242 0.0286 0.0262
Schistosoma mansoni protein kinase 0.0192 0.0148 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0138 0.0138
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0343 0.0558 0.0536
Leishmania major protein kinase, putative 0.0225 0.0238 0.0215
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Schistosoma mansoni cell polarity protein 0.0418 0.0763 0.0763
Echinococcus granulosus dual specificity 0.031 0.0469 0.0469
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Brugia malayi Calcium binding EGF domain containing protein 0.0418 0.0763 0.0763
Echinococcus multilocularis cyclin dependent kinase 5 0.0265 0.0347 0.0347
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0287 0.0407 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.088 0.2017 0.2017
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Brugia malayi Protein kinase domain containing protein 0.0343 0.0558 0.0558
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0262 0.034 0.1821
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Brugia malayi intracellular kinase 0.0287 0.0407 0.0407
Trichomonas vaginalis AGC family protein kinase 0.0399 0.0712 0.2168
Echinococcus multilocularis serine:threonine protein kinase 0.0255 0.0319 0.0319
Giardia lamblia Kinase, CMGC CK2 0.0223 0.0234 0.0334
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0273 0.0368 0.0345
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0276 0.0377 0.0377
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0496 0.0974 0.0974
Schistosoma mansoni tyrosine kinase 0.0143 0.0015 0.0015
Onchocerca volvulus 0.0319 0.0493 0.2205
Brugia malayi Prion-like- 0.0389 0.0683 0.0683
Echinococcus multilocularis 0.0269 0.0359 0.0359
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0713 0.1565 0.1565
Onchocerca volvulus 0.0713 0.1563 0.7093
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0452 0.0855 0.0855
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1103 0.2624 0.2624
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0185 0.0131 0.0131
Brugia malayi hypothetical protein 0.0718 0.1578 0.1578
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0278 0.0383 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.0603 0.1266 0.1266
Echinococcus multilocularis neuroglian 0.0875 0.2004 0.2004
Brugia malayi hypothetical protein 0.0249 0.0305 0.0305
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0203 0.0203
Trypanosoma cruzi cdc2-related kinase 1 0.0265 0.0347 0.0324
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Schistosoma mansoni glutamate synthase 0.0351 0.0581 0.0581
Onchocerca volvulus 0.0713 0.1563 0.7093
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0191 0.0147 0.0029
Brugia malayi Protein kinase domain containing protein 0.0255 0.0319 0.0319
Brugia malayi Prion-like- 0.0177 0.0108 0.0108
Schistosoma mansoni vam6/vps39 related 0.0249 0.0305 0.0305
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0189 0.014 0.0116
Schistosoma mansoni cell adhesion molecule 0.0212 0.0203 0.0203
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0392 0.0693 0.0693
Toxoplasma gondii AGC kinase 0.0252 0.0312 0.0289
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0409 0.0739 0.0739
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Toxoplasma gondii CMGC kinase, CK2 family 0.0223 0.0234 0.021
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0496 0.0974 0.0974
Echinococcus multilocularis cyclin dependent kinase 1 0.0265 0.0347 0.0347
Schistosoma mansoni nephrin 0.0409 0.0739 0.0739
Brugia malayi STE20-like kinase MST 0.0573 0.1184 0.1184
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0225 0.0238 0.0122
Schistosoma mansoni protein kinase 0.0969 0.2258 0.2258
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0351 0.0581 0.1762
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0969 0.2258 0.2258
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0283 0.0397 0.0397
Schistosoma mansoni nephrin related 0.0177 0.0108 0.0108
Brugia malayi pregnancy-associated plasma protein-A 0.0713 0.1563 0.1563
Echinococcus multilocularis mitogen activated protein kinase 11 0.0355 0.0592 0.0592
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0448 0.0844 0.0844
Entamoeba histolytica protein kinase, putative 0.0287 0.0407 0.2196
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0351 0.0581 0.3178
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0547 0.1113 0.1113
Loa Loa (eye worm) TK protein kinase 0.0204 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0468 0.0897 0.0897
Loa Loa (eye worm) hypothetical protein 0.0389 0.0685 0.0685
Schistosoma mansoni tyrosine kinase 0.054 0.1095 0.1095
Echinococcus granulosus casein kinase I delta 0.0242 0.0286 0.0286
Onchocerca volvulus 0.0412 0.0747 0.3364
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Echinococcus multilocularis hypothetical protein 0.0227 0.0245 0.0245
Brugia malayi Protein kinase domain containing protein 0.0484 0.0942 0.0942
Entamoeba histolytica protein kinase, putative 0.0147 0.0027 0.0057
Echinococcus multilocularis tyrosine protein kinase 0.0343 0.056 0.056
Echinococcus multilocularis serine:threonine protein kinase 0.0255 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0483 0.0938 0.0938
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Echinococcus multilocularis Glutaredoxin protein 5 0.0276 0.0377 0.0377
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0283 0.0397 0.0397
Trypanosoma cruzi NADH dehydrogenase, putative 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0393 0.1174
Trypanosoma brucei NADH dehydrogenase 0.0351 0.0581 0.0559
Echinococcus multilocularis CDC7 cell division cycle 7 0.02 0.0171 0.0171
Leishmania major hypothetical protein, conserved 0.0351 0.0581 0.0559
Onchocerca volvulus 0.0713 0.1563 0.7093
Schistosoma mansoni tyrosine kinase 0.054 0.1095 0.1095
Brugia malayi Kinase associated domain 1 family protein 0.0227 0.0245 0.0245
Echinococcus granulosus protein kinase c iota type 0.0638 0.1359 0.1359
Brugia malayi protein kinase C II. 0.0455 0.0864 0.0864
Echinococcus multilocularis dual specificity protein kinase clk2 0.0343 0.0558 0.0558
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0187 0.0135 0.0111
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Schistosoma mansoni titin 0.0389 0.0683 0.0683
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0351 0.0581 0.0559
Echinococcus granulosus dual specificity protein kinase clk2 0.0343 0.0558 0.0558
Plasmodium vivax thioredoxin reductase, putative 0.3819 1 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0289 0.0414 0.0414
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0365 0.062 0.062
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0937 0.0937
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0343 0.0558 0.0536
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0351 0.0581 0.0581
Echinococcus granulosus ephrin type A receptor 4 A 0.0216 0.0213 0.0213
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Schistosoma mansoni titin 0.0271 0.0362 0.0362
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1323 0.3222 0.3205
Giardia lamblia Kinase, CAMK CAMKL 0.0191 0.0147 0.0052
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0418 0.0763 0.0763
Schistosoma mansoni tyrosine kinase 0.0461 0.0881 0.0881
Echinococcus granulosus casein kinase i 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0412 0.0747 0.0747
Echinococcus granulosus titin 0.0271 0.0362 0.0362
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Brugia malayi Protein kinase domain containing protein 0.0671 0.145 0.145
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0189 0.014 0.0116
Brugia malayi ephrin receptor 1 precursor 0.014 0.0008 0.0008
Brugia malayi Protein kinase domain 0.0192 0.0148 0.0148
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Echinococcus granulosus down syndrome cell adhesion 0.0177 0.0108 0.0108
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0787 0.1765 0.8016
Echinococcus granulosus tyrosine protein kinase Srms 0.0607 0.1275 0.1275
Loa Loa (eye worm) hypothetical protein 0.1131 0.2698 0.2698
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Entamoeba histolytica protein kinase, putative 0.0185 0.0131 0.0641
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0603 0.1266 0.1266
Brugia malayi protein kinase C3,putative 0.0352 0.0583 0.0583
Echinococcus granulosus serine:threonine kinase SAD 1 0.0174 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0121 0.0121
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Schistosoma mansoni protein kinase 0.0146 0.0024 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus granulosus dual specificity 0.0273 0.0368 0.0368
Brugia malayi serine/threonine kinase 12 0.0262 0.034 0.034
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0252 0.0312 0.0289
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Schistosoma mansoni protein kinase 0.0242 0.0286 0.0286
Brugia malayi Leucine Rich Repeat family protein 0.0178 0.011 0.011
Echinococcus multilocularis insulin growth factor binding 0.0177 0.0108 0.0108
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0249 0.0305 0.0305
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) hypothetical protein 0.0802 0.1807 0.1807
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0351 0.0581 0.0559
Onchocerca volvulus Peroxidasin homolog 0.0178 0.011 0.0449
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.0622 0.0622
Echinococcus multilocularis dual specificity 0.031 0.0469 0.0469
Echinococcus granulosus serine:threonine protein kinase N2 0.0289 0.0414 0.0414
Toxoplasma gondii NADPH-glutathione reductase 0.1323 0.3222 0.3205
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0252 0.0312 0.0289
Giardia lamblia Kinase, AGC PKA 0.0349 0.0577 0.1442
Echinococcus multilocularis dual specificity 0.0273 0.0368 0.0368
Schistosoma mansoni protein kinase 0.043 0.0796 0.0796
Schistosoma mansoni protein kinase 0.0143 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.031 0.0469 0.0447
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0249 0.0305 0.0305
Giardia lamblia Kinase, STE STE20 0.0192 0.0148 0.0057
Schistosoma mansoni myosin-binding protein-related 0.0197 0.0163 0.0163
Schistosoma mansoni peroxidasin 0.0212 0.0204 0.0204
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0262 0.034 0.0225
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0407 0.2196
Trichomonas vaginalis CMGC family protein kinase 0.02 0.0171 0.0481
Echinococcus multilocularis nervana 2 0.0276 0.0377 0.0377
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0351 0.0581 0.1762
Echinococcus multilocularis N chimaerin 0.0167 0.0081 0.0081
Loa Loa (eye worm) cyclin C 0.157 0.3892 0.3892
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0713 0.1563 0.1563
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1323 0.3222 0.3205
Leishmania major hypothetical protein, conserved 0.025 0.0306 0.0282
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0197 0.0163 0.0163
Entamoeba histolytica protein kinase domain containing protein 0.0452 0.0855 0.472
Loa Loa (eye worm) hypothetical protein 0.0319 0.0493 0.0493
Loa Loa (eye worm) animal heme peroxidase 0.0177 0.0108 0.0108
Entamoeba histolytica protein kinase, putative 0.0273 0.0368 0.1977
Schistosoma mansoni tyrosine kinase 0.0468 0.0898 0.0898
Echinococcus multilocularis cyclin dependent kinase 1 0.0265 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1323 0.3222 1
Trypanosoma cruzi cdc2-related kinase 3 0.0265 0.0347 0.0324
Onchocerca volvulus 0.0177 0.0108 0.0442
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0359 0.0603 0.0603
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0351 0.0581 0.0581
Schistosoma mansoni rap gtpase-activating protein 0.0249 0.0305 0.0305
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0265 0.0347 0.0324
Onchocerca volvulus 0.0146 0.0025 0.0063
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0351 0.0581 0.0581
Schistosoma mansoni kinase 0.0169 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase 0.0343 0.056 0.056
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Schistosoma mansoni serine/threonine-protein kinase 0.0366 0.0622 0.0622
Echinococcus multilocularis thioredoxin glutathione reductase 0.3819 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0283 0.0397 0.0397
Trichomonas vaginalis CAMK family protein kinase 0.0255 0.0319 0.0942
Echinococcus multilocularis PAK box P21 Rho binding 0.0143 0.0017 0.0017
Trypanosoma cruzi cdc2-related kinase 1 0.0265 0.0347 0.0324
Echinococcus granulosus serine:threonine protein kinase 3 0.0573 0.1184 0.1184
Schistosoma mansoni tyrosine kinase 0.021 0.0197 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Brugia malayi Protein kinase domain containing protein 0.0322 0.0503 0.0503
Trichomonas vaginalis STE family protein kinase 0.0189 0.014 0.0385
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0212 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0197 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0699 0.1525 0.1525
Onchocerca volvulus 0.0271 0.0362 0.1606
Schistosoma mansoni cell adhesion molecule 0.0197 0.0163 0.0163
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0382 0.0666 0.0666
Plasmodium falciparum calcium-dependent protein kinase 2 0.0225 0.0238 0.0215
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0787 0.1765 0.1765
Giardia lamblia Kinase, NEK 0.0304 0.0452 0.104
Echinococcus multilocularis tyrosine kinase 0.0146 0.0025 0.0025
Schistosoma mansoni serine/threonine-protein kinase 0.0366 0.0622 0.0622
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Onchocerca volvulus 0.0697 0.1521 0.6901
Echinococcus granulosus glutamate synthase 0.0351 0.0581 0.0581
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0257 0.0325 0.0325
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0212 0.0203 0.0203
Brugia malayi Protein kinase domain containing protein 0.02 0.0171 0.0171
Brugia malayi glutamate synthase 0.0351 0.0581 0.0581
Trypanosoma cruzi trypanothione reductase, putative 0.1323 0.3222 0.3205
Onchocerca volvulus 0.0197 0.0163 0.0695
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0351 0.0581 0.0581
Entamoeba histolytica casein kinase, putative 0.0223 0.0234 0.1221
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.054 0.1095 0.1095
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Giardia lamblia Kinase, CMGC CLK 0.0343 0.0558 0.1384
Entamoeba histolytica PH domain containing protein kinase, putative 0.0269 0.0358 0.1921
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1323 0.3222 0.3205
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.088 0.2017 0.2017
Brugia malayi Protein kinase domain containing protein 0.043 0.0796 0.0796
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0212 0.0203 0.0203
Onchocerca volvulus 0.0177 0.0108 0.0442
Brugia malayi Tyrosine-protein kinase abl-1 0.021 0.0197 0.0197
Toxoplasma gondii histone kinase SNF1, putative 0.0174 0.0101 0.0077
Entamoeba histolytica thioredoxin reductase, putative 0.0351 0.0581 0.3178
Brugia malayi Egg laying defective protein 4 0.0188 0.0138 0.0138
Echinococcus granulosus Protein kinase C brain isozyme 0.0544 0.1105 0.1105
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0547 0.1113 0.1113
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0208 0.0191 0.0191
Loa Loa (eye worm) TK/ABL protein kinase 0.0146 0.0025 0.0025
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1323 0.3222 0.3205
Entamoeba histolytica protein kinase, putative 0.0225 0.0238 0.1246
Entamoeba histolytica protein kinase, putative 0.0652 0.1399 0.7779
Brugia malayi Immunoglobulin I-set domain containing protein 0.0409 0.0739 0.0739
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0287 0.0407 0.0384
Trypanosoma brucei aurora B kinase 0.0262 0.034 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.1065 0.2519 0.2519
Echinococcus multilocularis Immunoglobulin subtype 0.0212 0.0203 0.0203
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0189 0.014 0.0694
Brugia malayi Immunoglobulin domain containing protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0225 0.0238 0.0238
Onchocerca volvulus 0.0143 0.0016 0.002
Schistosoma mansoni septate junction protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0197 0.0163 0.0163
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0174 0.0101 0.0077
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Brugia malayi Protein kinase domain containing protein 0.0651 0.1395 0.1395
Toxoplasma gondii thioredoxin reductase 0.3819 1 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0351 0.0581 0.0581
Trichomonas vaginalis AGC family protein kinase 0.0382 0.0666 0.2025
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0223 0.0234 0.0117
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0249 0.0305 0.0282
Giardia lamblia Aurora kinase 0.0262 0.034 0.0678
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0232 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0669 0.1445 0.1445
Echinococcus multilocularis neural cadherin 0.0418 0.0763 0.0763
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0252 0.0312 0.0312
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0304 0.0452 0.0429
Schistosoma mansoni serine/threonine protein kinase 0.0569 0.1173 0.1173
Plasmodium vivax glycogen synthase kinase 3, putative 0.0287 0.0407 0.0292
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0174 0.0101 0.0077
Schistosoma mansoni ephrin receptor 0.0216 0.0213 0.0213
Echinococcus multilocularis dual specificity 0.031 0.0469 0.0469
Echinococcus multilocularis down syndrome cell adhesion 0.0177 0.0108 0.0108
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0174 0.0101 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0182 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Trypanosoma cruzi hypothetical protein, conserved 0.0351 0.0581 0.0559
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.0455 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0698 0.1523 0.1523
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3205
Onchocerca volvulus 0.0146 0.0025 0.0063
Loa Loa (eye worm) TK protein kinase 0.0415 0.0755 0.0755
Echinococcus granulosus serine threonine protein kinase nrc 0.0349 0.0577 0.0577
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0409 0.0739 0.0739
Loa Loa (eye worm) projectin 0.0197 0.0163 0.0163
Echinococcus granulosus cyclin dependent kinase 9 0.0185 0.0131 0.0131
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0343 0.0558 0.0536
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Brugia malayi notch-like transmembrane receptor 0.0418 0.0763 0.0763
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0225 0.0238 0.0238
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0182 0.0121 0.0121
Echinococcus granulosus mitogen activated protein kinase 11 0.0355 0.0592 0.0592
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0603 0.0603
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0378 0.0378
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0273 0.0368 0.0345
Brugia malayi Peroxidasin 0.0389 0.0685 0.0685
Brugia malayi Protein kinase c protein 2 0.0258 0.0328 0.0328
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.031 0.0469 0.0447
Loa Loa (eye worm) TK/FAK protein kinase 0.0651 0.1395 0.1395
Leishmania major protein kinase, putative 0.0262 0.034 0.0317
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Trypanosoma cruzi trypanothione reductase, putative 0.3819 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0086 0.0388
Echinococcus multilocularis tyrosine protein kinase otk 0.0389 0.0683 0.0683
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Echinococcus granulosus protein kinase 0.0342 0.0555 0.0555
Trichomonas vaginalis CK1 family protein kinase 0.0242 0.0286 0.0839
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0232 0.0258 0.0258
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0341 0.0555 0.0555
Echinococcus multilocularis lachesin 0.0389 0.0683 0.0683
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0819 0.1851 0.1851
Entamoeba histolytica protein kinase 2, putative 0.0349 0.0577 0.315
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0937 0.0937
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0351 0.0581 0.0581
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Schistosoma mansoni hypothetical protein 0.0227 0.0245 0.0245
Echinococcus granulosus Immunoglobulin 0.0212 0.0203 0.0203
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0351 0.0581 0.0559
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0349 0.0577 0.0577
Entamoeba histolytica protein kinase, putative 0.0182 0.0121 0.0585
Schistosoma mansoni serine/threonine protein kinase 0.0547 0.1113 0.1113
Brugia malayi Furin-like cysteine rich region family protein 0.0775 0.1733 0.1733
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0409 0.0739 0.0739
Loa Loa (eye worm) AUR protein kinase 0.0262 0.034 0.034
Trichomonas vaginalis CAMK family protein kinase 0.0484 0.0942 0.2888
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.031 0.0469 0.0447
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0972 0.2268 0.2268
Trypanosoma cruzi hypothetical protein, conserved 0.025 0.0306 0.0282
Echinococcus multilocularis tyrosine protein kinase Blk 0.0278 0.0383 0.0383
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Echinococcus granulosus neurogenic locus notch protein 0.0418 0.0763 0.0763
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1323 0.3222 1
Leishmania major protein kinase A catalytic subunit isoform 1 0.0252 0.0312 0.0289
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1323 0.3222 0.3141
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0225 0.0238 0.0238
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0273 0.0368 0.0368
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0242 0.0286 0.0286
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0238 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.1052 0.1052
Giardia lamblia Kinase, AGC AKT 0.0261 0.0337 0.0666
Loa Loa (eye worm) TK/INSR protein kinase 0.0671 0.145 0.145
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0349 0.0577 0.0577
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0452 0.0855 0.0855
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0177 0.0108 0.0108
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0486 0.0946 0.0946
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0347 0.0347
Mycobacterium tuberculosis Probable oxidoreductase 0.1323 0.3222 0.2803
Echinococcus granulosus tyrosine protein kinase Src42A 0.0208 0.0191 0.0191
Plasmodium vivax serine/threonine protein kinase, putative 0.0185 0.0131 0.0013
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0351 0.0581 0.0581
Echinococcus granulosus epidermal growth factor receptor 0.054 0.1095 0.1095
Echinococcus multilocularis roundabout 2 0.0409 0.0739 0.0739
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0544 0.1105 0.1105
Echinococcus granulosus casein kinase I alpha 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0199 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.0855 0.0855
Brugia malayi Protein kinase domain containing protein 0.0713 0.1565 0.1565
Plasmodium vivax casein kinase 1, putative 0.0242 0.0286 0.017
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0189 0.014 0.0116
Onchocerca volvulus 0.0177 0.0108 0.0442
Echinococcus granulosus cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0351 0.0581 0.0581
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0174 0.0101 0.0077
Loa Loa (eye worm) TK/KIN16 protein kinase 0.168 0.4189 0.4189
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Plasmodium vivax glutathione reductase, putative 0.3819 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0347 0.1031
Onchocerca volvulus 0.0146 0.0025 0.0063
Brugia malayi Immunoglobulin domain containing protein 0.0212 0.0203 0.0203
Leishmania major protein kinase A catalytic subunit 0.0252 0.0312 0.0289
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.025 0.0305 0.0305
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0603 0.1266 0.1266
Giardia lamblia High cysteine protein 0.0418 0.0763 0.2044
Entamoeba histolytica protein kinase, putative 0.0262 0.034 0.1821
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0496 0.0974 0.0974
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0187 0.0135 0.0111
Echinococcus multilocularis tissue type plasminogen activator 0.025 0.0306 0.0306
Echinococcus multilocularis cyclin 0.0786 0.1763 0.1763
Echinococcus granulosus aurora kinase A 0.0262 0.034 0.034
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Echinococcus multilocularis hemicentin 1 0.0389 0.0683 0.0683
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0406 0.073 0.073
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1323 0.3222 0.3205
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Echinococcus multilocularis serine:threonine protein kinase N2 0.0649 0.1389 0.1389
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0406 0.073 0.073
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0524 0.1052 0.1052
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0287 0.0407 0.0407
Onchocerca volvulus 0.0713 0.1563 0.7093
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0252 0.0312 0.0289
Brugia malayi Fibronectin type III domain containing protein 0.0718 0.1578 0.1578
Echinococcus granulosus nephrin 0.0197 0.0163 0.0163
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0389 0.0683 0.0683
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0351 0.0581 0.0559
Echinococcus granulosus raf serine:threonine protein kinase 0.0166 0.0078 0.0078
Schistosoma mansoni tyrosine kinase 0.0468 0.0898 0.0898
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Schistosoma mansoni tyrosine kinase 0.0468 0.0898 0.0898
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Plasmodium falciparum NIMA related kinase 1 0.0304 0.0452 0.0429
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.1052 0.1052
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Trichomonas vaginalis glutathione reductase, putative 0.1323 0.3222 1
Onchocerca volvulus 0.0177 0.0108 0.0442
Loa Loa (eye worm) hypothetical protein 0.1087 0.2579 0.2579
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0336 0.0541 0.0541
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0312 0.0312
Trichomonas vaginalis glutamate synthase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) TK protein kinase 0.0583 0.121 0.121
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis protein kinase c epsilon type 0.0455 0.0864 0.0864
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0698 0.1523 0.1523
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1323 0.3222 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.059 0.1229 0.1229
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1323 0.3222 1
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Loa Loa (eye worm) AUR protein kinase 0.0262 0.034 0.034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Echinococcus multilocularis netrin receptor unc 5 0.0276 0.0378 0.0378
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0351 0.0581 0.0581
Trichomonas vaginalis CK1 family protein kinase 0.0242 0.0286 0.0839
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Giardia lamblia Kinase, CMGC DYRK 0.031 0.0469 0.1096
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3205
Trypanosoma brucei rac serine-threonine kinase, putative 0.0652 0.1399 0.1378
Echinococcus granulosus tyrosine protein kinase ABL1 0.0146 0.0025 0.0025
Schistosoma mansoni serine/threonine protein kinase 0.0787 0.1765 0.1765
Schistosoma mansoni protein kinase 0.0969 0.2258 0.2258
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0351 0.0581 0.0581
Echinococcus granulosus tyrosine kinase 0.0278 0.0383 0.0383
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Trypanosoma cruzi Protein kinase B 0.0366 0.0622 0.06
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0351 0.0581 0.0559
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0192 0.0148 0.0148
Leishmania major protein kinase A catalytic subunit isoform 2 0.0252 0.0312 0.0289
Schistosoma mansoni serine/threonine kinase 0.0501 0.0988 0.0988
Echinococcus multilocularis expressed conserved protein 0.0188 0.0138 0.0138
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0343 0.0558 0.0536
Schistosoma mansoni disulfide oxidoreductase 0.0351 0.0581 0.0581
Echinococcus granulosus tyrosine protein kinase Src64B 0.0341 0.0555 0.0555
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Echinococcus granulosus growth factor receptor bound protein 2 0.0139 0.0006 0.0006
Schistosoma mansoni septate junction protein 0.0418 0.0763 0.0763
Schistosoma mansoni protein kinase 0.0493 0.0967 0.0967
Loa Loa (eye worm) hypothetical protein 0.0192 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0319 0.0493 0.0493
Giardia lamblia Kinase, PLK 0.0603 0.1266 0.3671
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0225 0.0238 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0286 0.0286
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0444 0.0444
Echinococcus granulosus tissue type plasminogen activator 0.025 0.0306 0.0306
Treponema pallidum NADH oxidase 0.1323 0.3222 1
Entamoeba histolytica casein kinase, putative 0.0242 0.0286 0.1513
Loa Loa (eye worm) hypothetical protein 0.0718 0.1578 0.1578
Echinococcus granulosus mitogen activated protein kinase 0.0187 0.0135 0.0135
Loa Loa (eye worm) CDC7 protein kinase 0.02 0.0171 0.0171
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0167 0.0081 0.0081
Toxoplasma gondii kringle domain-containing protein 0.025 0.0306 0.0282
Echinococcus multilocularis NCK adaptor protein 0.0139 0.0006 0.0006
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0225 0.0238 0.0215
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0225 0.0238 0.0215
Echinococcus multilocularis protein jagged 1 0.0418 0.0763 0.0763
Echinococcus granulosus cyclin dependent kinase 1 0.0265 0.0347 0.0347
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0351 0.0581 0.0559
Echinococcus granulosus C type lectin domian containing protein 0.0713 0.1563 0.1563
Echinococcus multilocularis mitogen activated protein kinase 14 0.0355 0.0592 0.0592
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0341 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.0518 0.1034 0.1034
Schistosoma mansoni cell adhesion molecule 0.0409 0.0739 0.0739
Schistosoma mansoni atypical protein kinase C 0.0651 0.1396 0.1396
Plasmodium vivax protein kinase Crk2 0.0265 0.0347 0.0232
Loa Loa (eye worm) hypothetical protein 0.091 0.2098 0.2098
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0786 0.1763 0.1763
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0351 0.0581 0.1762
Echinococcus multilocularis casein kinase I delta 0.0242 0.0286 0.0286
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0341 0.0555 0.0555
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.021 0.0197 0.0197
Entamoeba histolytica protein kinase, putative 0.0204 0.0182 0.0931
Echinococcus granulosus cyclin dependent kinase 5 0.0265 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0341 0.0555 0.0555
Brugia malayi casein kinase I 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0199 0.0169 0.0169
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0269 0.0359 0.0359
Echinococcus multilocularis mitogen activated protein kinase 0.0187 0.0135 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Entamoeba histolytica serine/threonine protein kinase, putative 0.0174 0.0101 0.0475
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0343 0.0558 0.0536
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0227 0.0243 0.0243
Brugia malayi Trypsin family protein 0.0644 0.1377 0.1377
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Onchocerca volvulus 0.0726 0.1598 0.7255
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0323 0.0505 0.0505
Echinococcus multilocularis serine:threonine protein kinase 38 0.0359 0.0603 0.0603
Loa Loa (eye worm) TK/FER protein kinase 0.0489 0.0955 0.0955
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0349 0.0577 0.0464
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0351 0.0581 0.3178
Brugia malayi Heparan sulfate 0.0212 0.0203 0.0203
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0262 0.034 0.034
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0969 0.2258 0.2258
Schistosoma mansoni protein kinase 0.0493 0.0967 0.0967
Brugia malayi p70 ribosomal S6 kinase beta 0.0635 0.1353 0.1353
Schistosoma mansoni tyrosine kinase 0.0341 0.0555 0.0555
Onchocerca volvulus 0.0652 0.1399 0.6344
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0204 0.0204
Schistosoma mansoni kinase 0.0644 0.1377 0.1377
Echinococcus granulosus dual specificity 0.031 0.0469 0.0469
Brugia malayi Protein kinase domain containing protein 0.034 0.055 0.055
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0744 0.1647 0.1647
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Onchocerca volvulus 0.0146 0.0025 0.0063
Loa Loa (eye worm) hypothetical protein 0.0429 0.0793 0.0793
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0273 0.0368 0.0345
Giardia lamblia Thioredoxin reductase 0.0351 0.0581 0.1458
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0362 0.0362
Loa Loa (eye worm) AGC/PKN protein kinase 0.0649 0.1389 0.1389
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1323 0.3222 0.3141
Echinococcus multilocularis neurogenic locus protein delta 0.0418 0.0763 0.0763
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1323 0.3222 0.3205
Brugia malayi Prion-like- 0.0177 0.0108 0.0108
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0342 0.0555 0.0555
Echinococcus granulosus protein jagged 2 0.0418 0.0763 0.0763
Echinococcus granulosus CDC7 cell division cycle 7 0.02 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0416 0.0758 0.0758
Echinococcus multilocularis casein kinase I alpha 0.0242 0.0286 0.0286
Echinococcus granulosus neurogenic locus notch protein 0.0418 0.0763 0.0763
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.043 0.0796 0.0796
Loa Loa (eye worm) hypothetical protein 0.0146 0.0025 0.0025
Entamoeba histolytica protein kinase domain containing protein 0.0273 0.0368 0.1977
Toxoplasma gondii AGC kinase 0.0252 0.0312 0.0289
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0262 0.034 0.034
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus serine:threonine protein kinase 0.0255 0.0319 0.0319
Brugia malayi Immunoglobulin I-set domain containing protein 0.0718 0.1578 0.1578
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0252 0.0312 0.0289
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0644 0.1377 0.1377
Echinococcus multilocularis neuroglian 0.0409 0.0739 0.0739
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0147 0.0027 0.0057
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0511 0.1015 0.1015
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0225 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis raf serine:threonine protein kinase 0.0166 0.0078 0.0078
Echinococcus multilocularis nervana 2 0.0276 0.0377 0.0377
Entamoeba histolytica PH domain containing protein kinase, putative 0.0366 0.0622 0.3409
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0972 0.2268 0.2268
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0197 0.0163 0.0163
Trichomonas vaginalis AGC family protein kinase 0.0376 0.0648 0.1971
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0635 0.1353 0.1353
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0177 0.0108 0.0108
Echinococcus granulosus tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0351 0.0581 0.0559
Brugia malayi serine/threonine-protein kinase plk-2 0.0603 0.1266 0.1266
Loa Loa (eye worm) gastrulation defective protein 1 0.0993 0.2324 0.2324
Echinococcus granulosus titin 0.0177 0.0108 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0489 0.0955 0.0955
Entamoeba histolytica protein kinase, putative 0.031 0.0469 0.2548
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.1105 0.1105
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1323 0.3222 1
Echinococcus multilocularis hemicentin 1 0.0389 0.0683 0.0683
Loa Loa (eye worm) LAD-2 short isoform 0.0212 0.0203 0.0203
Schistosoma mansoni vav2 0.0184 0.0127 0.0127
Toxoplasma gondii selenide, water dikinase 0.0351 0.0581 0.0559
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0178 0.011 0.011
Echinococcus multilocularis 0.0342 0.0555 0.0555
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Onchocerca volvulus 0.0429 0.0793 0.3574
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0351 0.0581 0.0469
Echinococcus granulosus epidermal growth factor receptor 0.0775 0.1733 0.1733
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Loa Loa (eye worm) hypothetical protein 0.0255 0.0319 0.0319
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Echinococcus granulosus c4b binding protein beta chain 0.0713 0.1563 0.1563
Brugia malayi probable protein kinase 0.0591 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.031 0.0469 0.0469
Schistosoma mansoni protein kinase 0.0262 0.034 0.034
Onchocerca volvulus 0.0287 0.0407 0.1809
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0185 0.0131 0.0107
Plasmodium vivax apical sushi protein, putative 0.0713 0.1563 0.1462
Onchocerca volvulus 0.0713 0.1563 0.7093
Trypanosoma cruzi NADH dehydrogenase, putative 0.0351 0.0581 0.0559
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0323 0.0504 0.0504
Trypanosoma cruzi polo-like protein kinase, putative 0.0603 0.1266 0.1245
Schistosoma mansoni basigin related 0.0212 0.0203 0.0203
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0225 0.0238 0.0215
Echinococcus granulosus hemicentin 1 0.0389 0.0683 0.0683
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1323 0.3222 0.2803
Echinococcus multilocularis neurogenic locus protein delta 0.0418 0.0763 0.0763
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0558 0.0558
Brugia malayi Cyclin C 0.157 0.3892 0.3892
Trichomonas vaginalis mercuric reductase, putative 0.1323 0.3222 1
Loa Loa (eye worm) hypothetical protein 0.0877 0.2008 0.2008
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0343 0.0558 0.0536
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Onchocerca volvulus Peroxidasin homolog 0.0177 0.0108 0.0442
Brugia malayi Immunoglobulin I-set domain containing protein 0.0409 0.0739 0.0739
Onchocerca volvulus 0.0177 0.0108 0.0442
Plasmodium falciparum cysteine repeat modular protein 1 0.025 0.0306 0.0282
Onchocerca volvulus 0.0351 0.0581 0.2607
Trypanosoma brucei protein kinase, putative 0.0203 0.018 0.0156
Schistosoma mansoni septate junction protein 0.0389 0.0683 0.0683
Brugia malayi serine/threonine protein kinase 6 0.0262 0.034 0.034
Echinococcus multilocularis epidermal growth factor receptor 0.054 0.1095 0.1095
Echinococcus granulosus serine:threonine protein kinase 0.0255 0.0319 0.0319
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0174 0.0101 0.0077
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0249 0.0305 0.0305
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Echinococcus multilocularis titin 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.1066 0.2524 0.2524
Onchocerca volvulus 0.0249 0.0305 0.1343
Schistosoma mansoni septate junction protein 0.0212 0.0203 0.0203
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0249 0.0305 0.0305
Echinococcus granulosus tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Echinococcus multilocularis epidermal growth factor receptor 0.0775 0.1733 0.1733
Schistosoma mansoni cell adhesion molecule 0.0177 0.0108 0.0108
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0484 0.0942 0.0942
Echinococcus multilocularis transfer RNA-Phe 0.0197 0.0163 0.0163
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0819 0.1851 0.1851
Brugia malayi casein kinase 1, delta 0.0242 0.0286 0.0286
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Echinococcus multilocularis calcium dependent protein kinase 0.0152 0.0039 0.0039
Echinococcus granulosus MAP kinase activated protein kinase 2 0.088 0.2017 0.2017
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0187 0.0135 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Entamoeba histolytica protein kinase domain containing protein 0.0262 0.034 0.1821
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0179 0.0113 0.0113
Brugia malayi cell division control protein 2 homolog 0.0265 0.0347 0.0347
Echinococcus granulosus protein jagged 1 0.0418 0.0763 0.0763
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0252 0.0312 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus granulosus fibroblast growth factor receptor 4 0.0406 0.073 0.073
Loa Loa (eye worm) hypothetical protein 0.0644 0.1377 0.1377
Loa Loa (eye worm) hypothetical protein 0.031 0.0469 0.0469
Schistosoma mansoni netrin receptor unc5 0.0276 0.0378 0.0378
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0755 0.1679 0.1679
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0197 0.0163 0.0163
Schistosoma mansoni tyrosine kinase 0.0314 0.0479 0.0479
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0227 0.0243 0.0243
Brugia malayi Protein kinase domain containing protein 0.0476 0.092 0.092
Schistosoma mansoni tyrosine kinase 0.0387 0.068 0.068
Entamoeba histolytica protein kinase, putative 0.016 0.0063 0.0259
Brugia malayi Protein kinase domain containing protein 0.0265 0.0347 0.0347
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Brugia malayi Variant SH3 domain containing protein 0.0167 0.0081 0.0081
Entamoeba histolytica PH domain containing protein kinase, putative 0.0366 0.0622 0.3409
Brugia malayi Protein kinase domain containing protein 0.0787 0.1765 0.1765
Trypanosoma brucei protein kinase, putative 0.0287 0.0407 0.0384
Echinococcus multilocularis tyrosine protein kinase HCK 0.0204 0.0182 0.0182
Echinococcus granulosus insulin receptor 0.0671 0.145 0.145
Brugia malayi Protein kinase domain containing protein 0.0314 0.048 0.048
Brugia malayi putative serine/threonine kinase SADA gamma 0.0174 0.0101 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.0351 0.0581 0.0559
Echinococcus granulosus roundabout 2 0.1107 0.2634 0.2634
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0169 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus granulosus hypothetical protein 0.0269 0.0359 0.0359
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Brugia malayi Protein kinase domain containing protein 0.0448 0.0844 0.0844
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Trypanosoma cruzi polo-like protein kinase, putative 0.0603 0.1266 0.1245
Entamoeba histolytica protein kinase, putative 0.0652 0.1399 0.7779
Brugia malayi Protein kinase domain containing protein 0.0138 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0189 0.014 0.0694
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0287 0.0407 0.0407
Echinococcus granulosus protein kinase C gamma type 0.0451 0.0851 0.0851
Trypanosoma brucei Casein kinase II 0.0223 0.0234 0.021
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0409 0.0739 0.0739
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0341 0.0555 0.0555
Toxoplasma gondii AGC kinase 0.0635 0.1353 0.1332
Brugia malayi Muscle positioning protein 4 0.0418 0.0763 0.0763
Brugia malayi Protein kinase domain containing protein 0.0366 0.0622 0.0622
Plasmodium falciparum calcium-dependent protein kinase 1 0.0225 0.0238 0.0215
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0644 0.1377 0.1377
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0573 0.1184 0.1184
Schistosoma mansoni protein kinase 0.0969 0.2258 0.2258
Schistosoma mansoni neuroglian 0.0409 0.0739 0.0739
Schistosoma mansoni hypothetical protein 0.0227 0.0245 0.0245
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3819 1 1
Brugia malayi basement membrane proteoglycan precursor 0.0212 0.0203 0.0203
Schistosoma mansoni g1/s-specific cyclin C 0.157 0.3892 0.3892
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0444 0.0444
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Schistosoma mansoni basigin related 0.0212 0.0203 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0496 0.0974 0.0974
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Echinococcus multilocularis aurora kinase A 0.0262 0.034 0.034
Brugia malayi Protein kinase domain containing protein 0.0273 0.0368 0.0368
Schistosoma mansoni sulfide quinone reductase 0.0351 0.0581 0.0581
Brugia malayi Serine/threonine-protein kinase SULU 0.0496 0.0974 0.0974
Loa Loa (eye worm) hypothetical protein 0.0143 0.0016 0.0016
Leishmania major protein kinase, putative 0.0343 0.0558 0.0536
Echinococcus granulosus nervana 2 0.0276 0.0377 0.0377
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0187 0.0135 0.0111
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Toxoplasma gondii casein kinase I 0.0242 0.0286 0.0262
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0351 0.0581 0.0559
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Onchocerca volvulus Serine\/threonine kinase homolog 0.0603 0.1266 0.5735
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0312 0.0312
Onchocerca volvulus 0.0146 0.0025 0.0063
Trypanosoma cruzi aurora B kinase, putative 0.0262 0.034 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0476 0.092 0.092
Loa Loa (eye worm) hypothetical protein 0.0644 0.1377 0.1377
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0341 0.0555 0.0555
Echinococcus multilocularis neurogenic locus notch protein 0.0418 0.0763 0.0763
Echinococcus multilocularis rho associated protein kinase 0.0726 0.1598 0.1598
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Giardia lamblia Kinase, STE STE20 0.0189 0.014 0.003
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1323 0.3222 0.3205
Echinococcus multilocularis twitchin 0.025 0.0307 0.0307
Onchocerca volvulus 0.0178 0.011 0.0449
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0366 0.0622 0.0622
Schistosoma mansoni septate junction protein 0.0389 0.0683 0.0683
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.031 0.0469 0.0469
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0366 0.0622 0.0622
Giardia lamblia Kinase, CMGC MAPK 0.0187 0.0135 0.0012
Echinococcus granulosus neural cadherin 0.0418 0.0763 0.0763
Onchocerca volvulus 0.0713 0.1563 0.7093
Brugia malayi MAP kinase sur-1 0.0187 0.0135 0.0135
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Echinococcus multilocularis serine:threonine protein kinase 3 0.0573 0.1184 0.1184
Giardia lamblia Kinase, CK1 Casein kinase 0.0242 0.0286 0.0501
Echinococcus multilocularis Immunoglobulin 0.0212 0.0203 0.0203
Entamoeba histolytica cell division protein kinase 2, putative 0.0265 0.0347 0.1859
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0355 0.0592 0.0569
Entamoeba histolytica disulphide oxidoreductase, putative 0.0351 0.0581 0.3178
Schistosoma mansoni ste20-related kinase 0.0458 0.0871 0.0871
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.059 0.1229 0.1229
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0452 0.0855 0.0855
Loa Loa (eye worm) hypothetical protein 0.0241 0.0283 0.0283
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Brugia malayi Cadherin domain containing protein 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Loa Loa (eye worm) disorganized muscle protein 1 0.0177 0.0108 0.0108
Brugia malayi Cyclin, N-terminal domain containing protein 0.0786 0.1763 0.1763
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0366 0.0622 0.06
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0351 0.0581 0.3178
Echinococcus granulosus protein kinase shaggy 0.0287 0.0407 0.0407
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Echinococcus granulosus neuroglian 0.0875 0.2004 0.2004
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2103 0.5338 0.5338
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0138 0.0138
Giardia lamblia Kinase, CMGC CDK 0.0265 0.0347 0.07
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0351 0.0581 0.0581
Plasmodium vivax unspecified product 0.0223 0.0234 0.0117
Brugia malayi Delta serrate ligand family protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.088 0.2017 0.2017
Trichomonas vaginalis CK1 family protein kinase 0.0242 0.0286 0.0839
Brugia malayi serine/threonine-protein kinase PAK 7 0.0518 0.1034 0.1034
Echinococcus granulosus cyclin dependent kinase 19 0.1066 0.2524 0.2524
Trichomonas vaginalis CAMK family protein kinase 0.0225 0.0238 0.0691
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0174 0.0101 0.0101
Echinococcus granulosus casein kinase I alpha 0.0242 0.0286 0.0286
Echinococcus multilocularis tyrosine protein kinase shark 0.0387 0.068 0.068
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0187 0.0135 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0583 0.121 0.121
Echinococcus multilocularis glutamate synthase 0.0351 0.0581 0.0581
Loa Loa (eye worm) notch protein 0.0418 0.0763 0.0763
Trichomonas vaginalis AGC family protein kinase 0.0252 0.0312 0.0921
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0187 0.0135 0.0111
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0182 0.0121 0.0121
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0351 0.0581 0.0581
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0448 0.0844 0.0844
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0343 0.0558 0.0558
Brugia malayi kettin 0.0177 0.0108 0.0108
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1629 0.4051 0.4051
Onchocerca volvulus 0.0169 0.0086 0.0344
Echinococcus granulosus nervana 2 0.0276 0.0377 0.0377
Echinococcus multilocularis c Jun NH2 terminal kinase 0.059 0.1229 0.1229
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0325 0.096
Echinococcus granulosus thioredoxin glutathione reductase 0.3819 1 1
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Echinococcus granulosus protein kinase c epsilon type 0.0455 0.0864 0.0864
Plasmodium falciparum casein kinase 1 0.0242 0.0286 0.0262
Echinococcus multilocularis c src tyrosine kinase 0.021 0.0197 0.0197
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0265 0.0347 0.0347
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0347 0.0347
Onchocerca volvulus 0.02 0.0171 0.0731
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.034 0.034
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0547 0.1113 0.1113
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0448 0.0844 0.0844
Giardia lamblia Kinase, CMGC CDK 0.0265 0.0347 0.07
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0167 0.0081 0.0081
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0325 0.096
Loa Loa (eye worm) thioredoxin reductase 0.3819 1 1
Echinococcus granulosus notch 0.0418 0.0763 0.0763
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Entamoeba histolytica protein kinase , putative 0.0262 0.034 0.1821
Schistosoma mansoni protein kinase 0.0819 0.1851 0.1851
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0135 0.0135
Echinococcus multilocularis protein jagged 1 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Entamoeba histolytica cyclin C, putative 0.0798 0.1793 1
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1103 0.2624 0.2624
Schistosoma mansoni hypothetical protein 0.025 0.0306 0.0306
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0347 0.1031
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0309 0.0466 0.1403
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Giardia lamblia Kinase, CDC7 0.02 0.0171 0.0131
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0185 0.0131 0.0107
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0223 0.0234 0.0234
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0179 0.0113 0.0113
Loa Loa (eye worm) TK/ALK protein kinase 0.034 0.055 0.055
Trichomonas vaginalis AGC family protein kinase 0.0182 0.0121 0.0324
Echinococcus granulosus neurogenic locus protein delta 0.0418 0.0763 0.0763
Loa Loa (eye worm) TK protein kinase 0.0278 0.0383 0.0383
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0188 0.0138 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Echinococcus multilocularis casein kinase I alpha 0.0242 0.0286 0.0286
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0232 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus titin 0.0177 0.0108 0.0108
Giardia lamblia Kinase, AGC PKA 0.0252 0.0312 0.0587
Echinococcus granulosus fibropellin Ia 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Echinococcus multilocularis mitogen activated protein kinase 11 0.0355 0.0592 0.0592
Plasmodium falciparum casein kinase 2, alpha subunit 0.0223 0.0234 0.021
Onchocerca volvulus Tyrosine kinase homolog 0.0947 0.2199 1
Brugia malayi Protein kinase domain containing protein 0.0432 0.0802 0.0802
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0278 0.0383 0.0383
Schistosoma mansoni hemicentin 0.0197 0.0163 0.0163
Echinococcus granulosus leucine rich repeat containing protein 4 0.0177 0.0108 0.0108
Echinococcus granulosus protein tyrosine kinase 0.0644 0.1376 0.1376
Brugia malayi Protein kinase domain containing protein 0.0359 0.0603 0.0603
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0351 0.0581 0.1458
Echinococcus granulosus calcium activated potassium channel 0.0301 0.0444 0.0444
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.1087 0.2579 0.2579
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0409 0.0739 0.0739
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0351 0.0581 0.3178
Trypanosoma brucei trypanothione reductase 0.3819 1 1
Echinococcus granulosus neuroglian 0.0409 0.0739 0.0739
Schistosoma mansoni protein kinase 0.0223 0.0234 0.0234
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0518 0.1034 0.1034
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0203 0.0203
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0212 0.0203 0.0203
Onchocerca volvulus Neurogenic locus notch homolog 0.0418 0.0763 0.3435
Echinococcus granulosus calcium dependent protein kinase 0.0152 0.0039 0.0039
Schistosoma mansoni sulfide quinone reductase 0.0351 0.0581 0.0581
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Onchocerca volvulus 0.0418 0.0763 0.3435
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0242 0.0286 0.0262
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0351 0.0581 0.0581
Echinococcus multilocularis ephrin type A receptor 4 A 0.0216 0.0213 0.0213
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Schistosoma mansoni tyrosine kinase 0.0406 0.073 0.073
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1323 0.3222 1
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0418 0.0763 0.3435
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0242 0.0286 0.0286
Brugia malayi SH2 domain containing protein 0.0146 0.0025 0.0025
Schistosoma mansoni cell adhesion molecule 0.093 0.2154 0.2154
Entamoeba histolytica hypothetical protein 0.0429 0.0792 0.4366
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0493 0.0967 0.0967
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0349 0.0577 0.0554
Onchocerca volvulus 0.0713 0.1563 0.7093
Echinococcus granulosus Glutaredoxin protein 5 0.0276 0.0377 0.0377
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Loa Loa (eye worm) hypothetical protein 0.0713 0.1565 0.1565
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0131 0.0131
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0257 0.0325 0.0325
Schistosoma mansoni tyrosine kinase 0.045 0.0849 0.0849
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0351 0.0581 0.0469
Schistosoma mansoni titin 0.0197 0.0163 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0397 0.0397
Schistosoma mansoni glutamate synthase 0.0351 0.0581 0.0581
Entamoeba histolytica PH domain containing protein kinase, putative 0.0269 0.0358 0.1921
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1217
Echinococcus granulosus twitchin 0.0948 0.2203 0.2203
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0212 0.0203 0.0203
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0351 0.0581 0.0559
Schistosoma mansoni protein kinase 0.0192 0.0148 0.0148
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Echinococcus granulosus tyrosine protein kinase Src42A 0.0341 0.0555 0.0555
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Entamoeba histolytica p21-activated kinase 0.0209 0.0194 0.0999
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0187 0.0135 0.0135
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0691 0.1505 0.1505
Entamoeba histolytica protein kinase, putative 0.0273 0.0368 0.1977
Onchocerca volvulus 0.0555 0.1135 0.5137
Loa Loa (eye worm) hypothetical protein 0.0225 0.0238 0.0238
Schistosoma mansoni basigin related 0.0212 0.0203 0.0203
Schistosoma mansoni cell adhesion molecule 0.0409 0.0739 0.0739
Echinococcus granulosus basement membrane specific heparan sulfate 0.0212 0.0203 0.0203
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0418 0.0763 0.0763
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0389 0.0683 0.0683
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0212 0.0203 0.0203
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0182 0.0121 0.0121
Echinococcus multilocularis 0.0177 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0262 0.034 0.1821
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Entamoeba histolytica protein kinase, putative 0.0228 0.0246 0.1289
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0198 0.0166 0.0166
Onchocerca volvulus 0.02 0.0171 0.0731
Echinococcus granulosus tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Echinococcus multilocularis protein jagged 2 0.0418 0.0763 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.062 0.1311 0.4038
Echinococcus multilocularis casein kinase I gamma 0.0476 0.092 0.092
Echinococcus multilocularis calcium activated potassium channel 0.0301 0.0444 0.0444
Plasmodium falciparum calcium-dependent protein kinase 3 0.0225 0.0238 0.0215
Trichomonas vaginalis apoptosis inducing factor, putative 0.0351 0.0581 0.1762
Trichomonas vaginalis STE family protein kinase 0.0304 0.0452 0.1359
Echinococcus granulosus peroxidasin 0.0389 0.0685 0.0685
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0252 0.0312 0.0289
Onchocerca volvulus 0.0197 0.0163 0.0695
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0265 0.0347 0.0324
Giardia lamblia Kinase, CAMK CAMKL 0.0191 0.0147 0.0052
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus granulosus N chimaerin 0.0167 0.0081 0.0081
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) SRC-1 0.0341 0.0555 0.0555
Echinococcus multilocularis titin 0.0271 0.0362 0.0362
Echinococcus granulosus c src tyrosine kinase 0.021 0.0197 0.0197
Onchocerca volvulus 0.0177 0.0108 0.0442
Schistosoma mansoni protein kinase 0.0591 0.1233 0.1233
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Loa Loa (eye worm) AGC/PKA protein kinase 0.0252 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0543 0.1101 0.1101
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0351 0.0581 0.0559
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0287 0.0407 0.0384
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi Temporarily assigned gene name protein 59 0.0288 0.041 0.041
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3222
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Schistosoma mansoni tyrosine kinase 0.0775 0.1733 0.1733
Schistosoma mansoni tyrosine kinase 0.0671 0.145 0.145
Echinococcus multilocularis neurogenic locus notch protein 0.0418 0.0763 0.0763
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0698 0.1523 0.1523
Echinococcus multilocularis Immunoglobulin 0.0698 0.1523 0.1523
Loa Loa (eye worm) AUR protein kinase 0.0262 0.034 0.034
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Brugia malayi Protein kinase domain containing protein 0.0819 0.1851 0.1851
Loa Loa (eye worm) one IG domain family member 0.0177 0.0108 0.0108
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1323 0.3222 1
Echinococcus multilocularis Immunoglobulin 0.0212 0.0203 0.0203
Brugia malayi C1-like domain containing protein 0.0486 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0192 0.0148 0.0148
Brugia malayi Protein kinase domain containing protein 0.0182 0.0121 0.0121
Plasmodium falciparum serine/threonine protein kinase 0.0185 0.0131 0.0107
Leishmania major casein kinase II, putative 0.0223 0.0234 0.021
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Onchocerca volvulus 0.025 0.0306 0.1347
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1323 0.3222 0.3222
Plasmodium falciparum apical sushi protein 0.0713 0.1563 0.1542
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0265 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0252 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0351 0.0581 0.3178
Echinococcus granulosus Immunoglobulin 0.0698 0.1523 0.1523
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0287 0.0407 0.0407
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0185 0.0131 0.0107
Echinococcus granulosus insulin growth factor binding 0.0177 0.0108 0.0108
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0181 0.0118 0.0094
Loa Loa (eye worm) hypothetical protein 0.031 0.0469 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.1105 0.1105
Onchocerca volvulus 0.0713 0.1563 0.7093
Echinococcus granulosus cyclin dependent kinase 9 0.0169 0.0086 0.0086
Loa Loa (eye worm) TK/EPH protein kinase 0.0255 0.0319 0.0319
Echinococcus granulosus tyrosine protein kinase Blk 0.0278 0.0383 0.0383
Echinococcus granulosus roundabout 2 0.0409 0.0739 0.0739
Leishmania major trypanothione reductase 0.3819 1 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0204 0.0182 0.0182
Echinococcus granulosus c-Jun N-terminal kinases 0.059 0.1229 0.1229
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0169 0.0086 0.0063
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0787 0.1765 0.1765
Loa Loa (eye worm) hypothetical protein 0.0403 0.0722 0.0722
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0212 0.0203 0.0203
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0265 0.0347 0.0324
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0177 0.0108 0.0108
Echinococcus granulosus titin 0.0177 0.0108 0.0108
Trypanosoma brucei polo-like protein kinase 0.0603 0.1266 0.1245
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Giardia lamblia Kinase, NEK 0.0304 0.0452 0.104
Entamoeba histolytica protein kinase, putative 0.0635 0.1353 0.752
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Leishmania major casein kinase, putative 0.0242 0.0286 0.0262
Echinococcus granulosus cGMP dependent protein kinase 0.0188 0.0138 0.0138
Brugia malayi EGF-like domain containing protein 0.0468 0.0897 0.0897
Echinococcus multilocularis protein tyrosine kinase 0.0644 0.1376 0.1376
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0167 0.0081 0.0081
Echinococcus multilocularis peroxidasin 0.0389 0.0685 0.0685
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0276 0.0377 0.0377
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0262 0.034 0.1821
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Loa Loa (eye worm) Notch2 0.0418 0.0763 0.0763
Plasmodium falciparum serine/threonine protein kinase KIN 0.0174 0.0101 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Brugia malayi map kinase activated protein kinase protein 2 0.088 0.2017 0.2017
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0355 0.0592 0.0569
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Brugia malayi Kringle domain containing protein 0.025 0.0306 0.0306
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3222
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0691 0.1505 0.1505
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0086 0.0086
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0181 0.0118 0.0094
Brugia malayi hypothetical protein 0.0146 0.0025 0.0025
Echinococcus multilocularis titin 0.0177 0.0108 0.0108
Echinococcus granulosus tyrosine kinase 0.0146 0.0025 0.0025
Echinococcus granulosus protein jagged 1 0.0418 0.0763 0.0763
Brugia malayi Protein kinase domain containing protein 0.0185 0.0131 0.0131
Brugia malayi Protein kinase domain containing protein 0.0382 0.0666 0.0666
Trichomonas vaginalis CMGC family protein kinase 0.02 0.0171 0.0481
Plasmodium vivax cysteine repeat modular protein 1, putative 0.025 0.0306 0.019
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0355 0.0592 0.0592
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.031 0.0469 0.0469
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0355 0.0592 0.0569
Schistosoma mansoni tyrosine kinase 0.0644 0.1376 0.1376
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Brugia malayi SRC-1 0.0341 0.0555 0.0555
Echinococcus granulosus titin 0.0271 0.0362 0.0362
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Loa Loa (eye worm) TK protein kinase 0.0343 0.056 0.056
Entamoeba histolytica serine/threonine protein kinase, putative 0.0603 0.1266 0.7029
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0249 0.0305 0.0305
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0389 0.0683 0.0683
Echinococcus granulosus defective proboscis extension response 0.0698 0.1523 0.1523
Onchocerca volvulus Slit protein homolog 0.0468 0.0897 0.4051
Echinococcus multilocularis Immunoglobulin 0.0698 0.1523 0.1523
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0167 0.0081 0.0081
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0165 0.0075 0.0075
Echinococcus multilocularis tyrosine protein kinase Srms 0.0278 0.0383 0.0383
Onchocerca volvulus 0.0418 0.0763 0.3435
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Leishmania major hypothetical protein, conserved 0.0351 0.0581 0.0559
Brugia malayi Protein kinase domain containing protein 0.2103 0.5338 0.5338
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0225 0.0238 0.0122
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Brugia malayi protein-tyrosine kinase 0.0278 0.0383 0.0383
Echinococcus granulosus tyrosine protein kinase Lyn 0.0415 0.0754 0.0754
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3222
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0171 0.0171
Trichomonas vaginalis AGC family protein kinase 0.0182 0.0121 0.0324
Brugia malayi RhoGAP domain containing protein 0.0167 0.0081 0.0081
Echinococcus multilocularis C type lectin domian containing protein 0.0713 0.1563 0.1563
Echinococcus multilocularis myosin iiia 0.0189 0.014 0.014
Echinococcus multilocularis slit 2 protein 0.0468 0.0897 0.0897
Onchocerca volvulus 0.0644 0.1377 0.6243
Echinococcus multilocularis mitogen activated protein kinase 3 0.0187 0.0135 0.0135
Schistosoma mansoni vesicular amine transporter 0.0698 0.1523 0.1523
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0252 0.0312 0.0289
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0486 0.0946 0.0946
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0518 0.1034 0.1034
Echinococcus granulosus roundabout 2 0.0409 0.0739 0.0739
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0389 0.0683 0.0683
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0787 0.1765 0.1765
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Onchocerca volvulus 0.0713 0.1563 0.7093
Echinococcus multilocularis cyclin dependent kinase 19 0.1066 0.2524 0.2524
Loa Loa (eye worm) glutathione reductase 0.3819 1 1
Echinococcus multilocularis cyclin dependent kinase 9 0.0185 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Echinococcus granulosus expressed protein 0.0185 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0416 0.0758 0.0758
Schistosoma mansoni laminin gamma-3 chain 0.0418 0.0763 0.0763
Brugia malayi Temporarily assigned gene name protein 59 0.0249 0.0305 0.0305
Brugia malayi Calcium binding EGF domain containing protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0235 0.0266 0.0266
Echinococcus granulosus tyrosine protein kinase shark 0.0387 0.068 0.068
Echinococcus granulosus Vam6:Vps39 protein 0.0249 0.0305 0.0305
Echinococcus granulosus casein kinase I alpha 0.0242 0.0286 0.0286
Schistosoma mansoni tyrosine kinase 0.0341 0.0555 0.0555
Plasmodium falciparum protein serine/threonine kinase-1 0.0343 0.0558 0.0536
Trypanosoma brucei SNF1-related protein kinases, putative 0.0174 0.0101 0.0077
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0409 0.0739 0.0739
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Giardia lamblia Glutamate synthase 0.0351 0.0581 0.1458
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Loa Loa (eye worm) protein kinase domain-containing protein 0.0476 0.092 0.092
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0187 0.0135 0.0111
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0366 0.0622 0.0622
Brugia malayi Hr1 repeat family protein 0.0649 0.1389 0.1389
Onchocerca volvulus 0.0177 0.0108 0.0442
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0787 0.1765 0.1765
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Echinococcus granulosus cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0227 0.0245 0.0245
Schistosoma mansoni c4b-binding protein beta chain 0.0713 0.1563 0.1563
Trypanosoma cruzi hypothetical protein, conserved 0.0351 0.0581 0.0559
Entamoeba histolytica protein kinase domain containing protein 0.031 0.0469 0.2548
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Entamoeba histolytica protein kinase, putative 0.0192 0.0148 0.074
Onchocerca volvulus 0.0242 0.0286 0.1255
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0255 0.0319 0.0319
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0393 0.1174
Trichomonas vaginalis glutamate synthase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) AGC/NDR protein kinase 0.0359 0.0603 0.0603
Schistosoma mansoni slit 0.0178 0.011 0.011
Loa Loa (eye worm) AGC/PKG protein kinase 0.0188 0.0138 0.0138
Schistosoma mansoni protein kinase 0.0342 0.0555 0.0555
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0312 0.0312
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0185 0.0131 0.0107
Onchocerca volvulus 0.0713 0.1563 0.7093
Plasmodium falciparum glutathione reductase 0.1323 0.3222 0.3205
Echinococcus granulosus rho-associated protein kinase 1 0.0726 0.1598 0.1598
Echinococcus multilocularis fibropellin Ia 0.0418 0.0763 0.0763
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0493 0.0967 0.0967
Echinococcus multilocularis 0.0215 0.0211 0.0211
Echinococcus granulosus casein kinase I gamma 0.0476 0.092 0.092
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0225 0.0238 0.0215
Echinococcus multilocularis death associated protein kinase 1 0.0994 0.2326 0.2326
Echinococcus granulosus tyrosine protein kinase otk 0.0389 0.0683 0.0683
Schistosoma mansoni glutamate synthase 0.0351 0.0581 0.0581
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0355 0.0592 0.0569
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0349 0.0577 0.0554
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0265 0.0347 0.0347
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Loa Loa (eye worm) AGC/PKA protein kinase 0.0252 0.0312 0.0312
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0278 0.0383 0.0359
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0351 0.0581 0.0559
Brugia malayi Fes/CIP4 homology domain containing protein 0.0228 0.0247 0.0247
Echinococcus granulosus neurogenic locus notch protein 4 0.0418 0.0763 0.0763
Brugia malayi cyclin-dependent kinase 9 0.0169 0.0086 0.0086
Echinococcus granulosus mitogen activated protein kinase 14 0.0355 0.0592 0.0592
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0197 0.0163 0.0163
Plasmodium falciparum cGMP-dependent protein kinase 0.0188 0.0138 0.0114
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0603 0.1266 0.1245
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Echinococcus multilocularis dual specificity 0.031 0.0469 0.0469
Trypanosoma brucei cdc2-related kinase 3 0.0265 0.0347 0.0324
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Plasmodium vivax calcium-dependent protein kinase, putative 0.0225 0.0238 0.0122
Loa Loa (eye worm) hypothetical protein 0.0249 0.0305 0.0305
Schistosoma mansoni slit 0.0419 0.0764 0.0764
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Echinococcus multilocularis titin 0.0177 0.0108 0.0108
Echinococcus multilocularis tyrosine protein kinase Abl 0.021 0.0197 0.0197
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0351 0.0581 0.0559
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0187 0.0135 0.0111
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0713 0.1565 0.1565
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0351 0.0581 0.0581
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0323 0.0505 0.0505
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0287 0.0407 0.0407
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0524 0.1052 0.1052
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0261 0.0337 0.0337
Echinococcus multilocularis casein kinase i 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0266 0.0349 0.0349
Onchocerca volvulus Serine\/threonine kinase homolog 0.0366 0.0622 0.2791
Brugia malayi Animal haem peroxidase family protein 0.0177 0.0108 0.0108
Brugia malayi Protein kinase domain containing protein 0.1001 0.2346 0.2346
Brugia malayi Cadherin domain containing protein 0.0418 0.0763 0.0763
Plasmodium vivax ferrodoxin reductase, putative 0.0351 0.0581 0.0469
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0347 0.1031
Entamoeba histolytica protein kinase, putative 0.0262 0.034 0.1821
Loa Loa (eye worm) hypothetical protein 0.0197 0.0163 0.0163
Echinococcus granulosus delta-like protein 1 0.0418 0.0763 0.0763
Schistosoma mansoni nephrin 0.0895 0.2059 0.2059
Loa Loa (eye worm) hypothetical protein 0.0271 0.0362 0.0362
Echinococcus granulosus netrin receptor unc 5 0.0276 0.0378 0.0378
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0024 0.004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0409 0.0739 0.0739
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0511 0.1015 0.1015
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0786 0.1763 0.1763
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Brugia malayi hypothetical protein 0.0496 0.0974 0.0974
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0351 0.0581 0.0581
Loa Loa (eye worm) hypothetical protein 0.0698 0.1523 0.1523
Entamoeba histolytica casein kinase 1, putative 0.0242 0.0286 0.1513
Schistosoma mansoni roundabout 0.0389 0.0683 0.0683
Entamoeba histolytica protein kinase domain containing protein 0.0223 0.0234 0.1221
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0455 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Trichomonas vaginalis AGC family protein kinase 0.0198 0.0166 0.0466
Plasmodium falciparum protein kinase 5 0.0265 0.0347 0.0324
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0407 0.2196
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Loa Loa (eye worm) cyclin domain-containing protein 0.0786 0.1763 0.1763
Echinococcus multilocularis cyclin dependent kinase 0.0265 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0341 0.0555 0.0555
Trypanosoma brucei cdc2-related kinase 1 0.0265 0.0347 0.0324
Echinococcus multilocularis insulin receptor 0.0671 0.145 0.145
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Echinococcus multilocularis serine:threonine protein kinase N2 0.0359 0.0603 0.0603
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) programmed cell death 8 0.0351 0.0581 0.0581
Echinococcus granulosus slit 2 protein 0.0468 0.0897 0.0897
Brugia malayi Protein kinase domain containing protein 0.0652 0.1399 0.1399
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Onchocerca volvulus 0.0418 0.0763 0.3435
Brugia malayi Immunoglobulin I-set domain containing protein 0.0232 0.0258 0.0258
Echinococcus granulosus low density lipoprotein receptor ldl 0.0212 0.0203 0.0203
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0273 0.0368 0.0345
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0359 0.0603 0.0603
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Schistosoma mansoni tyrosine kinase 0.021 0.0197 0.0197
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1001 0.2346 0.2346
Echinococcus granulosus serine/threonine protein kinase 0.0366 0.0622 0.0622
Schistosoma mansoni serine/threonine protein kinase 0.0726 0.1598 0.1598
Echinococcus multilocularis fat cadherin tumor suppressor 0.0418 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0444 0.0444
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0177 0.0108 0.0108
Plasmodium falciparum thioredoxin reductase 0.1323 0.3222 0.3205
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0252 0.0312 0.0289
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0603 0.1266 0.1266
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.025 0.0305 0.0305
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0343 0.0558 0.0536
Plasmodium falciparum ferrodoxin reductase-like protein 0.0351 0.0581 0.0559
Onchocerca volvulus 0.0418 0.0763 0.3435
Onchocerca volvulus Putative cubilin 0.0418 0.0763 0.3435
Toxoplasma gondii EGF family domain-containing protein 0.0418 0.0763 0.074
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Echinococcus multilocularis casein kinase ii subunit alpha 0.0223 0.0234 0.0234
Echinococcus multilocularis rac serine:threonine kinase 0.0366 0.0622 0.0622
Echinococcus multilocularis protein kinase shaggy 0.0287 0.0407 0.0407
Brugia malayi Immunoglobulin domain containing protein 0.0212 0.0203 0.0203
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0146 0.0025 0.0025
Echinococcus granulosus cyclin dependent kinase 0.0265 0.0347 0.0347

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.66 uM Inhibitory concentration value against murine P-388 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human A-549 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon adenocarcinoma HT-29 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human MEL-28 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon carcinoma H-116 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against murine P-388 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human A-549 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon adenocarcinoma HT-29 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human MEL-28 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon carcinoma H-116 tumor cell line ChEMBL. 15658869

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 15658869
Mus musculus ChEMBL23 15658869

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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