Detailed information for compound 313456

Basic information

Technical information
  • TDR Targets ID: 313456
  • Name: N,N-dimethyl-4-[(E)-2-naphthalen-2-ylethenyl] aniline
  • MW: 273.372 | Formula: C20H19N
  • H donors: 0 H acceptors: 0 LogP: 5.56 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ccc(cc1)/C=C/c1ccc2c(c1)cccc2)C
  • InChi: 1S/C20H19N/c1-21(2)20-13-10-16(11-14-20)7-8-17-9-12-18-5-3-4-6-19(18)15-17/h3-15H,1-2H3/b8-7+
  • InChiKey: RRDADBSXDJUDCW-BQYQJAHWSA-N  

Network

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Synonyms

  • N,N-dimethyl-4-[(E)-2-(2-naphthyl)vinyl]aniline
  • N,N-dimethyl-4-[(E)-2-(2-naphthalenyl)vinyl]aniline
  • dimethyl-[4-[(E)-2-(2-naphthyl)vinyl]phenyl]amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Brugia malayi Protein kinase c protein 2 0.0258 0.0328 0.0328
Brugia malayi Protein kinase domain containing protein 0.0476 0.092 0.092
Loa Loa (eye worm) hypothetical protein 0.0644 0.1377 0.1377
Echinococcus multilocularis casein kinase I alpha 0.0242 0.0286 0.0286
Echinococcus granulosus Immunoglobulin 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0412 0.0747 0.0747
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Schistosoma mansoni protein kinase 0.0493 0.0967 0.0967
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.088 0.2017 0.2017
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0351 0.0581 0.0559
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0351 0.0581 0.3178
Echinococcus multilocularis glutamate synthase 0.0351 0.0581 0.0581
Onchocerca volvulus 0.0418 0.0763 0.3435
Onchocerca volvulus 0.0177 0.0108 0.0442
Brugia malayi Temporarily assigned gene name protein 59 0.0249 0.0305 0.0305
Echinococcus granulosus casein kinase ii subunit alpha 0.0223 0.0234 0.0234
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0366 0.0622 0.0622
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0287 0.0407 0.0384
Trichomonas vaginalis AGC family protein kinase 0.0182 0.0121 0.0324
Giardia lamblia Kinase, CMGC CDK 0.0265 0.0347 0.07
Brugia malayi serine/threonine kinase 12 0.0262 0.034 0.034
Echinococcus granulosus casein kinase I delta 0.0242 0.0286 0.0286
Echinococcus granulosus tyrosine protein kinase Srms 0.0607 0.1275 0.1275
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0418 0.0763 0.3435
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.031 0.0469 0.0447
Loa Loa (eye worm) hypothetical protein 0.0389 0.0685 0.0685
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0223 0.0234 0.0234
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1103 0.2624 0.2624
Entamoeba histolytica serine/threonine protein kinase, putative 0.0174 0.0101 0.0475
Loa Loa (eye worm) TK protein kinase 0.0415 0.0755 0.0755
Schistosoma mansoni cell adhesion molecule 0.0197 0.0163 0.0163
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Schistosoma mansoni basigin related 0.0212 0.0203 0.0203
Schistosoma mansoni serine/threonine-protein kinase 0.0366 0.0622 0.0622
Echinococcus granulosus calcium activated potassium channel 0.0301 0.0444 0.0444
Schistosoma mansoni hemicentin 0.0197 0.0163 0.0163
Brugia malayi Prion-like- 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0131 0.0131
Brugia malayi Thioredoxin reductase 0.3819 1 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0713 0.1565 0.1565
Treponema pallidum NADH oxidase 0.1323 0.3222 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0278 0.0383 0.0383
Onchocerca volvulus 0.0697 0.1521 0.6901
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1323 0.3222 1
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0287 0.0407 0.0407
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0262 0.034 0.034
Entamoeba histolytica p21-activated kinase 0.0209 0.0194 0.0999
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0212 0.0203 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0455 0.0864 0.0864
Loa Loa (eye worm) LAD-2 short isoform 0.0212 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0351 0.0581 0.0581
Echinococcus multilocularis aurora kinase A 0.0262 0.034 0.034
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0185 0.0131 0.0131
Schistosoma mansoni nephrin related 0.0177 0.0108 0.0108
Onchocerca volvulus 0.025 0.0306 0.1347
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0524 0.1052 0.1052
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0452 0.0855 0.0855
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0312 0.0312
Echinococcus multilocularis twitchin 0.025 0.0307 0.0307
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis c4b binding protein beta chain 0.0713 0.1563 0.1563
Onchocerca volvulus 0.0351 0.0581 0.2607
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus granulosus tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Echinococcus multilocularis 0.0269 0.0359 0.0359
Echinococcus multilocularis cyclin dependent kinase 9 0.0169 0.0086 0.0086
Entamoeba histolytica protein kinase, putative 0.0225 0.0238 0.1246
Schistosoma mansoni basigin related 0.0212 0.0203 0.0203
Echinococcus multilocularis serine:threonine protein kinase 0.0255 0.0319 0.0319
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0558 0.0558
Schistosoma mansoni septate junction protein 0.0418 0.0763 0.0763
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0343 0.0558 0.0536
Loa Loa (eye worm) disorganized muscle protein 1 0.0177 0.0108 0.0108
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0547 0.1113 0.1113
Echinococcus granulosus serine threonine protein kinase nrc 0.0349 0.0577 0.0577
Schistosoma mansoni titin 0.0389 0.0683 0.0683
Echinococcus multilocularis roundabout 2 0.0409 0.0739 0.0739
Brugia malayi Protein kinase domain containing protein 0.0343 0.056 0.056
Echinococcus granulosus serine:threonine protein kinase 0.0255 0.0319 0.0319
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0351 0.0581 0.0581
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Entamoeba histolytica cell division protein kinase 2, putative 0.0265 0.0347 0.1859
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Echinococcus granulosus c-Jun N-terminal kinases 0.059 0.1229 0.1229
Brugia malayi casein kinase 1, delta 0.0242 0.0286 0.0286
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1323 0.3222 1
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Brugia malayi STE20-like kinase MST 0.0573 0.1184 0.1184
Echinococcus multilocularis casein kinase i 0.0242 0.0286 0.0286
Brugia malayi SH2 domain containing protein 0.0146 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0225 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Schistosoma mansoni nephrin 0.0409 0.0739 0.0739
Toxoplasma gondii EGF family domain-containing protein 0.0418 0.0763 0.074
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Onchocerca volvulus 0.0713 0.1563 0.7093
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Echinococcus granulosus tyrosine protein kinase HCK 0.0204 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0255 0.0319 0.0319
Plasmodium falciparum protein serine/threonine kinase-1 0.0343 0.0558 0.0536
Entamoeba histolytica protein kinase, putative 0.0147 0.0027 0.0057
Echinococcus multilocularis neurogenic locus protein delta 0.0418 0.0763 0.0763
Schistosoma mansoni serine/threonine kinase 0.0359 0.0603 0.0603
Echinococcus multilocularis transfer RNA-Phe 0.0197 0.0163 0.0163
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0252 0.0312 0.0312
Giardia lamblia Kinase, NEK 0.0304 0.0452 0.104
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Giardia lamblia NADH oxidase lateral transfer candidate 0.1323 0.3222 1
Brugia malayi kettin 0.0177 0.0108 0.0108
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Brugia malayi Kinase associated domain 1 family protein 0.0227 0.0245 0.0245
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0351 0.0581 0.0559
Brugia malayi Protein kinase domain containing protein 0.043 0.0796 0.0796
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0271 0.0362 0.0362
Schistosoma mansoni tyrosine kinase 0.0468 0.0898 0.0898
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0355 0.0592 0.0569
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0249 0.0305 0.0305
Leishmania major hypothetical protein, conserved 0.0351 0.0581 0.0559
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Echinococcus granulosus hemicentin 1 0.0389 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0444 0.0444
Echinococcus multilocularis mitogen activated protein kinase 0.0187 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0225 0.0238 0.0122
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Echinococcus multilocularis 0.0215 0.0211 0.0211
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Brugia malayi Immunoglobulin I-set domain containing protein 0.0583 0.121 0.121
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0232 0.0258 0.0258
Echinococcus granulosus neurogenic locus notch protein 0.0418 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0496 0.0974 0.0974
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Brugia malayi Delta serrate ligand family protein 0.0418 0.0763 0.0763
Plasmodium falciparum calcium-dependent protein kinase 2 0.0225 0.0238 0.0215
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0787 0.1765 0.1765
Trichomonas vaginalis CAMK family protein kinase 0.062 0.1311 0.4038
Brugia malayi probable protein kinase 0.0591 0.1233 0.1233
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0351 0.0581 0.0581
Schistosoma mansoni tyrosine kinase 0.0644 0.1376 0.1376
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0351 0.0581 0.1458
Brugia malayi cyclin-dependent kinase 9 0.0169 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0718 0.1578 0.1578
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0496 0.0974 0.0974
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Giardia lamblia Kinase, AGC PKA 0.0349 0.0577 0.1442
Echinococcus granulosus titin 0.0177 0.0108 0.0108
Echinococcus granulosus tyrosine protein kinase 0.0343 0.056 0.056
Brugia malayi serine/threonine-protein kinase 6 0.0262 0.034 0.034
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0341 0.0555 0.0555
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0486 0.0946 0.0946
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Brugia malayi notch-like transmembrane receptor 0.0418 0.0763 0.0763
Echinococcus granulosus protein kinase 0.0342 0.0555 0.0555
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0351 0.0581 0.0559
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0937 0.0937
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Echinococcus granulosus twitchin 0.0948 0.2203 0.2203
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0182 0.0121 0.0121
Echinococcus granulosus NDR protein kinase 0.0359 0.0603 0.0603
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3205
Echinococcus multilocularis hypothetical protein 0.0227 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0182 0.0121 0.0121
Giardia lamblia Kinase, CMGC GSK 0.0287 0.0407 0.0894
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Brugia malayi Tyrosine-protein kinase abl-1 0.021 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0241 0.0283 0.0283
Toxoplasma gondii AGC kinase 0.0635 0.1353 0.1332
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Loa Loa (eye worm) notch protein 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Loa Loa (eye worm) protein kinase domain-containing protein 0.0476 0.092 0.092
Trypanosoma cruzi hypothetical protein, conserved 0.0351 0.0581 0.0559
Echinococcus granulosus roundabout 2 0.0409 0.0739 0.0739
Echinococcus multilocularis casein kinase I delta 0.0242 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Plasmodium vivax thioredoxin reductase, putative 0.3819 1 1
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0257 0.0325 0.0325
Brugia malayi pregnancy-associated plasma protein-A 0.0713 0.1563 0.1563
Echinococcus granulosus hypothetical protein 0.0269 0.0359 0.0359
Echinococcus multilocularis fibropellin Ia 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0232 0.0258 0.0258
Echinococcus granulosus leucine rich repeat containing protein 4 0.0177 0.0108 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0349 0.0577 0.0577
Entamoeba histolytica protein kinase, putative 0.0262 0.034 0.1821
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0787 0.1765 0.1765
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.1052 0.1052
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0389 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0726 0.1598 0.1598
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0603 0.1266 0.1266
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0786 0.1763 0.1763
Echinococcus granulosus cyclin dependent kinase 0.0265 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase otk 0.0389 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Brugia malayi Immunoglobulin I-set domain containing protein 0.0409 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0669 0.1445 0.1445
Echinococcus granulosus low density lipoprotein receptor ldl 0.0212 0.0203 0.0203
Echinococcus multilocularis titin 0.0177 0.0108 0.0108
Brugia malayi Fibronectin type III domain containing protein 0.0718 0.1578 0.1578
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0182 0.0121 0.0121
Brugia malayi Calcium binding EGF domain containing protein 0.0418 0.0763 0.0763
Entamoeba histolytica protein kinase, putative 0.0273 0.0368 0.1977
Trypanosoma cruzi Protein kinase B 0.0366 0.0622 0.06
Echinococcus granulosus casein kinase I alpha 0.0242 0.0286 0.0286
Echinococcus multilocularis neuroglian 0.0409 0.0739 0.0739
Trypanosoma cruzi casein kinase II, putative 0.0223 0.0234 0.021
Schistosoma mansoni hypothetical protein 0.0227 0.0245 0.0245
Onchocerca volvulus 0.0287 0.0407 0.1809
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Echinococcus granulosus mitogen activated protein kinase 11 0.0355 0.0592 0.0592
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0265 0.0347 0.0347
Plasmodium falciparum ferrodoxin reductase-like protein 0.0351 0.0581 0.0559
Schistosoma mansoni neuroglian 0.0409 0.0739 0.0739
Brugia malayi hypothetical protein 0.0212 0.0203 0.0203
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0341 0.0555 0.0555
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0265 0.0347 0.0324
Echinococcus multilocularis mitogen activated protein kinase 3 0.0187 0.0135 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Echinococcus multilocularis casein kinase I delta 0.0242 0.0286 0.0286
Brugia malayi Immunoglobulin domain containing protein 0.0212 0.0203 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0255 0.0319 0.0942
Trichomonas vaginalis mercuric reductase, putative 0.1323 0.3222 1
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0177 0.0108 0.0108
Loa Loa (eye worm) TK/ROR protein kinase 0.0499 0.0984 0.0984
Entamoeba histolytica protein kinase, putative 0.0652 0.1399 0.7779
Leishmania major protein kinase A catalytic subunit isoform 2 0.0252 0.0312 0.0289
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0187 0.0135 0.0111
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0174 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.091 0.2098 0.2098
Echinococcus granulosus down syndrome cell adhesion 0.0177 0.0108 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Onchocerca volvulus Peroxidasin homolog 0.0177 0.0108 0.0442
Plasmodium vivax cysteine repeat modular protein 1, putative 0.025 0.0306 0.019
Entamoeba histolytica protein kinase, putative 0.0287 0.0407 0.2196
Brugia malayi Cadherin domain containing protein 0.0418 0.0763 0.0763
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0192 0.0148 0.0148
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0167 0.0081 0.0081
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0225 0.0238 0.0122
Plasmodium falciparum calcium-dependent protein kinase 4 0.0225 0.0238 0.0215
Echinococcus multilocularis tyrosine protein kinase Srms 0.0278 0.0383 0.0383
Schistosoma mansoni tyrosine kinase 0.0314 0.0479 0.0479
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Toxoplasma gondii NADPH-glutathione reductase 0.1323 0.3222 0.3205
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Entamoeba histolytica protein kinase, putative 0.0359 0.0603 0.33
Entamoeba histolytica protein kinase domain containing protein 0.0223 0.0234 0.1221
Schistosoma mansoni hypothetical protein 0.0227 0.0245 0.0245
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0223 0.0234 0.0117
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0351 0.0581 0.0581
Trypanosoma cruzi hypothetical protein, conserved 0.0351 0.0581 0.0559
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1323 0.3222 1
Brugia malayi hypothetical protein 0.0496 0.0974 0.0974
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0212 0.0203 0.0203
Entamoeba histolytica protein kinase, putative 0.0182 0.0121 0.0585
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Echinococcus multilocularis cyclin 0.0786 0.1763 0.1763
Onchocerca volvulus 0.0555 0.1135 0.5137
Schistosoma mansoni tyrosine kinase 0.0406 0.073 0.073
Entamoeba histolytica PH domain containing protein kinase, putative 0.0269 0.0358 0.1921
Echinococcus granulosus protein kinase c epsilon type 0.0455 0.0864 0.0864
Loa Loa (eye worm) gastrulation defective protein 1 0.0993 0.2324 0.2324
Echinococcus multilocularis protein kinase c iota type 0.0638 0.1359 0.1359
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.091 0.2098 0.2098
Onchocerca volvulus Serine\/threonine kinase homolog 0.0603 0.1266 0.5735
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0713 0.1563 0.1563
Schistosoma mansoni serine/threonine protein kinase 0.0547 0.1113 0.1113
Brugia malayi Calcium binding EGF domain containing protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0323 0.0505 0.0505
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0351 0.0581 0.3178
Brugia malayi Immunoglobulin I-set domain containing protein 0.0232 0.0258 0.0258
Onchocerca volvulus 0.0429 0.0793 0.3574
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0086 0.0086
Brugia malayi protein kinase C3,putative 0.0352 0.0583 0.0583
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi Protein kinase domain containing protein 0.0713 0.1565 0.1565
Trypanosoma cruzi cdc2-related kinase 1 0.0265 0.0347 0.0324
Onchocerca volvulus 0.0418 0.0763 0.3435
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0351 0.0581 0.0559
Echinococcus granulosus tyrosine kinase 0.0146 0.0025 0.0025
Onchocerca volvulus 0.0169 0.0086 0.0344
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0389 0.0683 0.0683
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0341 0.0555 0.0555
Toxoplasma gondii aurora kinase 0.0262 0.034 0.0317
Brugia malayi RhoGAP domain containing protein 0.0167 0.0081 0.0081
Schistosoma mansoni tyrosine kinase 0.0341 0.0555 0.0555
Echinococcus multilocularis Immunoglobulin 0.0212 0.0203 0.0203
Plasmodium falciparum glutathione reductase 0.3819 1 1
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0276 0.0377 0.0377
Loa Loa (eye worm) programmed cell death 8 0.0351 0.0581 0.0581
Echinococcus granulosus cyclin dependent kinase 9 0.0185 0.0131 0.0131
Trypanosoma cruzi trypanothione reductase, putative 0.3819 1 1
Loa Loa (eye worm) hypothetical protein 0.0197 0.0163 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Onchocerca volvulus 0.0177 0.0108 0.0442
Brugia malayi putative serine/threonine kinase SADA gamma 0.0174 0.0101 0.0101
Brugia malayi Serine/threonine-protein kinase SULU 0.0496 0.0974 0.0974
Schistosoma mansoni hypothetical protein 0.0249 0.0305 0.0305
Echinococcus multilocularis neuroglian 0.0875 0.2004 0.2004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0389 0.0683 0.0683
Brugia malayi Protein kinase domain containing protein 0.0343 0.0558 0.0558
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2103 0.5338 0.5338
Leishmania major protein kinase, putative 0.0343 0.0558 0.0536
Brugia malayi Protein kinase domain containing protein 0.0359 0.0603 0.0603
Echinococcus multilocularis Immunoglobulin 0.0212 0.0203 0.0203
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0573 0.1184 0.1184
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0786 0.1763 0.1763
Schistosoma mansoni tyrosine kinase 0.0468 0.0898 0.0898
Echinococcus granulosus Vam6:Vps39 protein 0.0249 0.0305 0.0305
Echinococcus granulosus Immunoglobulin subtype 0.0212 0.0203 0.0203
Plasmodium falciparum thioredoxin reductase 0.3819 1 1
Brugia malayi Egg laying defective protein 4 0.0188 0.0138 0.0138
Echinococcus granulosus tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Schistosoma mansoni serine/threonine protein kinase 0.0787 0.1765 0.1765
Brugia malayi P38 map kinase family protein 2 0.0355 0.0592 0.0592
Entamoeba histolytica protein kinase domain containing protein 0.031 0.0469 0.2548
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0187 0.0135 0.0111
Schistosoma mansoni g1/s-specific cyclin C 0.157 0.3892 0.3892
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0351 0.0581 0.0559
Plasmodium falciparum calcium-dependent protein kinase 5 0.0225 0.0238 0.0215
Toxoplasma gondii rhoptry neck protein RON9 0.0713 0.1563 0.1542
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis thioredoxin glutathione reductase 0.3819 1 1
Trypanosoma brucei protein kinase, putative 0.0287 0.0407 0.0384
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0227 0.0245 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0382 0.0666 0.2025
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Echinococcus granulosus notch 0.0418 0.0763 0.0763
Brugia malayi hypothetical protein 0.0249 0.0305 0.0305
Loa Loa (eye worm) TK/FER protein kinase 0.0489 0.0955 0.0955
Echinococcus multilocularis NCK adaptor protein 0.0139 0.0006 0.0006
Echinococcus granulosus protein kinase c iota type 0.0638 0.1359 0.1359
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.025 0.0305 0.0305
Onchocerca volvulus 0.0146 0.0025 0.0063
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Brugia malayi Protein kinase domain containing protein 0.0185 0.0131 0.0131
Schistosoma mansoni vav2 0.0184 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Trypanosoma cruzi aurora B kinase, putative 0.0262 0.034 0.0317
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0351 0.0581 0.0559
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Toxoplasma gondii rhoptry neck protein RON1 0.0713 0.1563 0.1542
Loa Loa (eye worm) hypothetical protein 0.0319 0.0493 0.0493
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0252 0.0312 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Schistosoma mansoni cell adhesion molecule 0.0409 0.0739 0.0739
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0351 0.0581 0.0559
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Brugia malayi Fes/CIP4 homology domain containing protein 0.0228 0.0247 0.0247
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0452 0.0855 0.0855
Echinococcus granulosus Immunoglobulin 0.0698 0.1523 0.1523
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0351 0.0581 0.0581
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0351 0.0581 0.0581
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Schistosoma mansoni titin 0.0271 0.0362 0.0362
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3222
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis titin 0.0271 0.0362 0.0362
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0278 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.103 0.2425 0.2425
Echinococcus granulosus raf serine:threonine protein kinase 0.0166 0.0078 0.0078
Brugia malayi Protein kinase domain containing protein 0.0651 0.1395 0.1395
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Schistosoma mansoni serine/threonine protein kinase 0.088 0.2017 0.2017
Echinococcus granulosus tyrosine protein kinase ABL1 0.0146 0.0025 0.0025
Echinococcus granulosus expressed protein 0.0185 0.0131 0.0131
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0406 0.073 0.073
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0182 0.0121 0.0121
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Brugia malayi Cyclin C 0.157 0.3892 0.3892
Echinococcus granulosus casein kinase i 0.0242 0.0286 0.0286
Schistosoma mansoni cell adhesion molecule 0.093 0.2154 0.2154
Onchocerca volvulus 0.02 0.0171 0.0731
Echinococcus multilocularis neural cadherin 0.0418 0.0763 0.0763
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0227 0.0243 0.0243
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.1052 0.1052
Giardia lamblia Glutamate synthase 0.0351 0.0581 0.1458
Schistosoma mansoni hypothetical protein 0.0197 0.0163 0.0163
Brugia malayi Protein kinase domain containing protein 0.034 0.055 0.055
Schistosoma mansoni protein kinase 0.0342 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.0143 0.0016 0.0016
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.031 0.0469 0.0447
Onchocerca volvulus 0.0713 0.1563 0.7093
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1217
Trypanosoma cruzi hypothetical protein, conserved 0.025 0.0306 0.0282
Giardia lamblia Kinase, CAMK CAMKL 0.0191 0.0147 0.0052
Loa Loa (eye worm) TK/ALK protein kinase 0.034 0.055 0.055
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Onchocerca volvulus 0.0418 0.0763 0.3435
Brugia malayi Peroxidasin 0.0389 0.0685 0.0685
Brugia malayi Protein kinase domain containing protein 0.0448 0.0844 0.0844
Giardia lamblia Thioredoxin reductase 0.0351 0.0581 0.1458
Giardia lamblia Kinase, CMGC GSK 0.0287 0.0407 0.0894
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0603 0.1266 0.1266
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Schistosoma mansoni septate junction protein 0.0389 0.0683 0.0683
Echinococcus granulosus tyrosine protein kinase Src64B 0.0341 0.0555 0.0555
Entamoeba histolytica protein kinase, putative 0.0635 0.1353 0.752
Onchocerca volvulus 0.0652 0.1399 0.6344
Entamoeba histolytica protein kinase , putative 0.0262 0.034 0.1821
Trichomonas vaginalis CAMK family protein kinase 0.0484 0.0942 0.2888
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1103 0.2624 0.2624
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0187 0.0187
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0325 0.096
Loa Loa (eye worm) hypothetical protein 0.0249 0.0305 0.0305
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0249 0.0305 0.0305
Schistosoma mansoni tyrosine kinase 0.0671 0.145 0.145
Onchocerca volvulus 0.0713 0.1563 0.7093
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0225 0.0238 0.0238
Echinococcus granulosus c src tyrosine kinase 0.021 0.0197 0.0197
Echinococcus granulosus cGMP dependent protein kinase 0.0188 0.0138 0.0138
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0343 0.0558 0.0558
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0393 0.1174
Echinococcus granulosus c4b binding protein beta chain 0.0713 0.1563 0.1563
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) TK/FAK protein kinase 0.0651 0.1395 0.1395
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Schistosoma mansoni slit 0.0178 0.011 0.011
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Schistosoma mansoni tyrosine kinase 0.0461 0.0881 0.0881
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0418 0.0763 0.0763
Echinococcus multilocularis tissue type plasminogen activator 0.025 0.0306 0.0306
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0341 0.0555 0.0555
Schistosoma mansoni glutamate synthase 0.0351 0.0581 0.0581
Loa Loa (eye worm) cyclin domain-containing protein 0.0786 0.1763 0.1763
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0208 0.0191 0.0191
Echinococcus multilocularis nervana 2 0.0276 0.0377 0.0377
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0252 0.0312 0.0289
Echinococcus multilocularis serine threonine protein kinase 0.0451 0.0851 0.0851
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0312 0.0312
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0287 0.0407 0.0407
Loa Loa (eye worm) hypothetical protein 0.0718 0.1578 0.1578
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0187 0.0135 0.0111
Plasmodium falciparum serine/threonine protein kinase, putative 0.0262 0.034 0.0317
Schistosoma mansoni tyrosine kinase 0.0468 0.0898 0.0898
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.054 0.1095 0.1095
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3205
Loa Loa (eye worm) AUR protein kinase 0.0262 0.034 0.034
Giardia lamblia Kinase, CMGC MAPK 0.0187 0.0135 0.0012
Loa Loa (eye worm) hypothetical protein 0.031 0.0469 0.0469
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus N chimaerin 0.0167 0.0081 0.0081
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0225 0.0238 0.0215
Onchocerca volvulus 0.0143 0.0016 0.002
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0351 0.0581 0.0581
Entamoeba histolytica protein kinase, putative 0.0262 0.034 0.1821
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1629 0.4051 0.4051
Trichomonas vaginalis AGC family protein kinase 0.0198 0.0166 0.0466
Schistosoma mansoni myosin-binding protein-related 0.0197 0.0163 0.0163
Echinococcus multilocularis insulin growth factor binding 0.0177 0.0108 0.0108
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Entamoeba histolytica PH domain containing protein kinase, putative 0.0366 0.0622 0.3409
Schistosoma mansoni tyrosine kinase 0.0341 0.0555 0.0555
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0351 0.0581 0.0469
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0086 0.0388
Brugia malayi SH2 domain containing protein 0.0489 0.0955 0.0955
Brugia malayi Muscle positioning protein 4 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Echinococcus multilocularis death associated protein kinase 1 0.0994 0.2326 0.2326
Brugia malayi protein-tyrosine kinase 0.0278 0.0383 0.0383
Schistosoma mansoni c4b-binding protein beta chain 0.0713 0.1563 0.1563
Brugia malayi phosphoinositide-dependent protein kinase I 0.0182 0.0121 0.0121
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Echinococcus multilocularis casein kinase I alpha 0.0242 0.0286 0.0286
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0349 0.0577 0.0464
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1323 0.3222 0.2803
Onchocerca volvulus 0.0713 0.1563 0.7093
Echinococcus multilocularis neurogenic locus notch protein 0.0418 0.0763 0.0763
Echinococcus granulosus cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Toxoplasma gondii CMGC kinase, CK2 family 0.0223 0.0234 0.021
Brugia malayi Casein kinase II, alpha chain 0.0223 0.0234 0.0234
Onchocerca volvulus 0.0713 0.1563 0.7093
Leishmania major casein kinase, putative 0.0242 0.0286 0.0262
Echinococcus granulosus tyrosine protein kinase shark 0.0387 0.068 0.068
Trypanosoma brucei polo-like protein kinase 0.0603 0.1266 0.1245
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0355 0.0592 0.0569
Echinococcus granulosus serine:threonine kinase SAD 1 0.0174 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0312 0.0312
Entamoeba histolytica protein kinase, putative 0.0228 0.0246 0.1289
Entamoeba histolytica protein kinase, putative 0.031 0.0469 0.2548
Brugia malayi basement membrane proteoglycan 0.0212 0.0203 0.0203
Trypanosoma brucei casein kinase I, isoform 2 0.0242 0.0286 0.0262
Echinococcus multilocularis titin 0.0177 0.0108 0.0108
Schistosoma mansoni cell adhesion molecule 0.0409 0.0739 0.0739
Brugia malayi p70 ribosomal S6 kinase beta 0.0635 0.1353 0.1353
Onchocerca volvulus 0.0197 0.0163 0.0695
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis serine:threonine protein kinase 0.0255 0.0319 0.0319
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Plasmodium falciparum protein kinase 5 0.0265 0.0347 0.0324
Trichomonas vaginalis glutamate synthase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) AGC/NDR protein kinase 0.0359 0.0603 0.0603
Echinococcus granulosus mitogen activated protein kinase 3 0.0187 0.0135 0.0135
Plasmodium falciparum calcium-dependent protein kinase 1 0.0225 0.0238 0.0215
Echinococcus granulosus tyrosine protein kinase Lyn 0.0415 0.0754 0.0754
Loa Loa (eye worm) one IG domain family member 0.0177 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0341 0.0555 0.0555
Loa Loa (eye worm) hypothetical protein 0.0269 0.0359 0.0359
Schistosoma mansoni netrin receptor unc5 0.0276 0.0378 0.0378
Schistosoma mansoni kinase 0.0169 0.0086 0.0086
Entamoeba histolytica serine/threonine protein kinase, putative 0.0603 0.1266 0.7029
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0225 0.0238 0.0238
Echinococcus multilocularis cyclin dependent kinase 9 0.0185 0.0131 0.0131
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1323 0.3222 0.3205
Echinococcus granulosus titin 0.0271 0.0362 0.0362
Echinococcus multilocularis casein kinase I gamma 0.0476 0.092 0.092
Leishmania major protein kinase A catalytic subunit isoform 1 0.0252 0.0312 0.0289
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Leishmania major protein kinase, putative 0.0343 0.0558 0.0536
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0225 0.0238 0.0215
Echinococcus granulosus dual specificity protein kinase clk2 0.0343 0.0558 0.0558
Entamoeba histolytica cyclin C, putative 0.0798 0.1793 1
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0138 0.0138
Brugia malayi Doublecortin family protein 0.0336 0.0541 0.0541
Brugia malayi cell division control protein 2 homolog 0.0265 0.0347 0.0347
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0225 0.0238 0.0238
Brugia malayi Protein kinase domain containing protein 0.2103 0.5338 0.5338
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0744 0.1647 0.1647
Echinococcus granulosus serine:threonine protein kinase 0.0255 0.0319 0.0319
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0351 0.0581 0.0581
Schistosoma mansoni serine/threonine-protein kinase 0.0366 0.0622 0.0622
Echinococcus granulosus aurora kinase A 0.0262 0.034 0.034
Onchocerca volvulus 0.0713 0.1563 0.7093
Echinococcus multilocularis dual specificity 0.0273 0.0368 0.0368
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Brugia malayi Trypsin family protein 0.0644 0.1377 0.1377
Trypanosoma cruzi polo-like protein kinase, putative 0.0603 0.1266 0.1245
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Giardia lamblia Kinase, CMGC CLK 0.0343 0.0558 0.1384
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0351 0.0581 0.3178
Loa Loa (eye worm) TK/KIN16 protein kinase 0.168 0.4189 0.4189
Echinococcus granulosus nervana 2 0.0276 0.0377 0.0377
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0448 0.0844 0.0844
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1323 0.3222 0.3141
Echinococcus granulosus cyclin 0.0786 0.1763 0.1763
Plasmodium falciparum thioredoxin reductase 0.1323 0.3222 0.3205
Schistosoma mansoni protein kinase 0.0143 0.0017 0.0017
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0185 0.0131 0.0107
Echinococcus multilocularis cyclin dependent kinase 19 0.1066 0.2524 0.2524
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Leishmania major hypothetical protein, conserved 0.0351 0.0581 0.0559
Echinococcus granulosus Immunoglobulin 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Loa Loa (eye worm) hypothetical protein 0.0235 0.0266 0.0266
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0744 0.1647 0.1647
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Brugia malayi C1-like domain containing protein 0.0486 0.0946 0.0946
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Onchocerca volvulus 0.0319 0.0493 0.2205
Brugia malayi Protein kinase domain containing protein 0.0484 0.0942 0.0942
Schistosoma mansoni rap gtpase-activating protein 0.0249 0.0305 0.0305
Schistosoma mansoni vesicular amine transporter 0.0698 0.1523 0.1523
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0262 0.034 0.034
Schistosoma mansoni protein kinase C mu 0.0486 0.0946 0.0946
Mycobacterium tuberculosis Probable oxidoreductase 0.1323 0.3222 0.2803
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1323 0.3222 0.3205
Echinococcus multilocularis Immunoglobulin subtype 0.0212 0.0203 0.0203
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Echinococcus multilocularis rho associated protein kinase 0.0726 0.1598 0.1598
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0265 0.0347 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0101 0.0101
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0351 0.0581 0.3178
Echinococcus multilocularis c src tyrosine kinase 0.021 0.0197 0.0197
Schistosoma mansoni slit 0.0419 0.0764 0.0764
Schistosoma mansoni serine/threonine kinase 0.0501 0.0988 0.0988
Brugia malayi MAP kinase sur-1 0.0187 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.0146 0.0025 0.0025
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0174 0.0101 0.0077
Loa Loa (eye worm) hypothetical protein 0.0644 0.1377 0.1377
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Onchocerca volvulus Peroxidasin homolog 0.0178 0.011 0.0449
Entamoeba histolytica casein kinase 1, putative 0.0242 0.0286 0.1513
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0359 0.0603 0.0603
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0167 0.0081 0.0081
Entamoeba histolytica thioredoxin reductase, putative 0.0351 0.0581 0.3178
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0212 0.0203 0.0203
Loa Loa (eye worm) TK protein kinase 0.0343 0.056 0.056
Loa Loa (eye worm) hypothetical protein 0.0199 0.0169 0.0169
Schistosoma mansoni cell adhesion molecule 0.0389 0.0683 0.0683
Schistosoma mansoni tyrosine kinase 0.021 0.0197 0.0197
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.0622 0.0622
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0511 0.1015 0.1015
Echinococcus multilocularis ephrin type A receptor 4 A 0.0216 0.0213 0.0213
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.1105 0.1105
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0569 0.1173 0.1173
Schistosoma mansoni protein kinase 0.043 0.0796 0.0796
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0347 0.1031
Echinococcus multilocularis Glutaredoxin protein 5 0.0276 0.0377 0.0377
Echinococcus multilocularis nervana 2 0.0276 0.0377 0.0377
Entamoeba histolytica protein kinase domain containing protein 0.0262 0.034 0.1821
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0351 0.0581 0.1762
Schistosoma mansoni sulfide quinone reductase 0.0351 0.0581 0.0581
Echinococcus multilocularis neurogenic locus notch protein 0.0418 0.0763 0.0763
Echinococcus granulosus peroxidasin 0.0389 0.0685 0.0685
Giardia lamblia Aurora kinase 0.0262 0.034 0.0678
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0484 0.0942 0.0942
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0351 0.0581 0.0559
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0493 0.0967 0.0967
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0286 0.0286
Echinococcus granulosus nervana 2 0.0276 0.0377 0.0377
Brugia malayi SRC-1 0.0341 0.0555 0.0555
Echinococcus multilocularis 0.0342 0.0555 0.0555
Toxoplasma gondii AGC kinase 0.0252 0.0312 0.0289
Loa Loa (eye worm) projectin 0.0197 0.0163 0.0163
Trichomonas vaginalis CK1 family protein kinase 0.0242 0.0286 0.0839
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trichomonas vaginalis AGC family protein kinase 0.0262 0.034 0.1009
Giardia lamblia Kinase, NEK 0.0304 0.0452 0.104
Giardia lamblia Kinase, CMGC CK2 0.0223 0.0234 0.0334
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0355 0.0592 0.0569
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0225 0.0238 0.0215
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0212 0.0203 0.0203
Onchocerca volvulus Tyrosine kinase homolog 0.0947 0.2199 1
Schistosoma mansoni cell adhesion molecule 0.0197 0.0163 0.0163
Echinococcus granulosus epidermal growth factor receptor 0.054 0.1095 0.1095
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0819 0.1851 0.1851
Echinococcus multilocularis tyrosine protein kinase shark 0.0387 0.068 0.068
Brugia malayi hypothetical protein 0.0146 0.0025 0.0025
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0273 0.0368 0.0345
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Brugia malayi Immunoglobulin I-set domain containing protein 0.0227 0.0243 0.0243
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Trichomonas vaginalis STE family protein kinase 0.0192 0.0148 0.041
Echinococcus multilocularis tyrosine protein kinase Blk 0.0278 0.0383 0.0383
Brugia malayi Protein kinase domain containing protein 0.0314 0.048 0.048
Schistosoma mansoni basigin related 0.0212 0.0203 0.0203
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0177 0.0108 0.0108
Echinococcus granulosus casein kinase I delta 0.0242 0.0286 0.0286
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0409 0.0739 0.0739
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0351 0.0581 0.0559
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Schistosoma mansoni vam6/vps39 related 0.0249 0.0305 0.0305
Brugia malayi Protein kinase domain containing protein 0.0273 0.0368 0.0368
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0287 0.0407 0.0407
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0283 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0199 0.0169 0.0169
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0249 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0649 0.1389 0.1389
Onchocerca volvulus Putative cubilin 0.0418 0.0763 0.3435
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus MAP kinase activated protein kinase 2 0.088 0.2017 0.2017
Brugia malayi Protein kinase domain containing protein 0.0138 0.0002 0.0002
Schistosoma mansoni roundabout 0.0389 0.0683 0.0683
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0341 0.0555 0.0555
Onchocerca volvulus 0.0242 0.0286 0.1255
Echinococcus multilocularis calcium activated potassium channel 0.0301 0.0444 0.0444
Echinococcus granulosus neuroglian 0.0875 0.2004 0.2004
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Plasmodium vivax serine/threonine protein kinase, putative 0.0185 0.0131 0.0013
Echinococcus granulosus tyrosine protein kinase Blk 0.0278 0.0383 0.0383
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0787 0.1765 0.1765
Brugia malayi Immunoglobulin domain containing protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1001 0.2346 0.2346
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0368 0.0368
Echinococcus multilocularis roundabout 2 0.1107 0.2634 0.2634
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0225 0.0238 0.0238
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0366 0.0622 0.0622
Schistosoma mansoni netrin receptor unc5 0.0212 0.0203 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0544 0.1105 0.1105
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0185 0.0131 0.0107
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Brugia malayi serine/threonine-protein kinase plk-2 0.0603 0.1266 0.1266
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis protein jagged 1 0.0418 0.0763 0.0763
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1066 0.2524 0.2524
Schistosoma mansoni serine/threonine protein kinase 0.0482 0.0937 0.0937
Echinococcus multilocularis PAK box P21 Rho binding 0.0143 0.0017 0.0017
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.031 0.0469 0.0447
Plasmodium vivax serine/threonine kinase-1, putative 0.0343 0.0558 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Brugia malayi Kringle domain containing protein 0.025 0.0306 0.0306
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0261 0.0337 0.0337
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0452 0.0855 0.0855
Loa Loa (eye worm) hypothetical protein 0.0699 0.1525 0.1525
Loa Loa (eye worm) hypothetical protein 0.0698 0.1523 0.1523
Loa Loa (eye worm) AGC/AKT protein kinase 0.0652 0.1399 0.1399
Brugia malayi Immunoglobulin I-set domain containing protein 0.0276 0.0378 0.0378
Schistosoma mansoni tyrosine kinase 0.045 0.0849 0.0849
Echinococcus granulosus netrin receptor unc 5 0.0276 0.0378 0.0378
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Trypanosoma brucei Casein kinase II 0.0223 0.0234 0.021
Echinococcus multilocularis fat cadherin tumor suppressor 0.0418 0.0763 0.0763
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0265 0.0347 0.0347
Echinococcus granulosus neurogenic locus notch protein 0.0418 0.0763 0.0763
Leishmania major trypanothione reductase 0.3819 1 1
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0351 0.0581 0.0559
Schistosoma mansoni protein kinase 0.0192 0.0148 0.0148
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0409 0.0739 0.0739
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0343 0.0558 0.0536
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0189 0.014 0.0116
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0304 0.0452 0.0429
Echinococcus multilocularis down syndrome cell adhesion 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Echinococcus multilocularis tyrosine kinase 0.0146 0.0025 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Brugia malayi Immunoglobulin I-set domain containing protein 0.168 0.4189 0.4189
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Plasmodium vivax unspecified product 0.0223 0.0234 0.0117
Onchocerca volvulus 0.0271 0.0362 0.1606
Schistosoma mansoni tyrosine kinase 0.0143 0.0015 0.0015
Onchocerca volvulus 0.0146 0.0025 0.0063
Echinococcus granulosus tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0262 0.034 0.0225
Giardia lamblia Kinase, STE STE20 0.0189 0.014 0.003
Echinococcus multilocularis neurogenic locus notch protein 4 0.0418 0.0763 0.0763
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0351 0.0581 0.0559
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Loa Loa (eye worm) TK protein kinase 0.0278 0.0383 0.0383
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0197 0.0163 0.0163
Brugia malayi Protein kinase domain containing protein 0.0382 0.0666 0.0666
Echinococcus multilocularis Immunoglobulin 0.0698 0.1523 0.1523
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Echinococcus multilocularis casein kinase ii subunit alpha 0.0223 0.0234 0.0234
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0547 0.1113 0.1113
Giardia lamblia Kinase, CK1 Casein kinase 0.0242 0.0286 0.0501
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0185 0.0131 0.0107
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Schistosoma mansoni protein kinase 0.0223 0.0234 0.0234
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0283 0.0397 0.0397
Plasmodium falciparum serine/threonine protein kinase 0.0185 0.0131 0.0107
Echinococcus granulosus fibroblast growth factor receptor 4 0.0406 0.073 0.073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.031 0.0469 0.0447
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.034 0.034
Leishmania major NADH dehydrogenase, putative 0.0351 0.0581 0.0559
Brugia malayi Temporarily assigned gene name protein 59 0.0288 0.041 0.041
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0359 0.0603 0.0603
Brugia malayi Stress-activated protein kinase jnk-1 0.059 0.1229 0.1229
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0271 0.0362 0.0362
Trypanosoma cruzi cdc2-related kinase 1 0.0265 0.0347 0.0324
Onchocerca volvulus 0.0197 0.0163 0.0695
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0409 0.0739 0.0739
Brugia malayi Animal haem peroxidase family protein 0.0177 0.0108 0.0108
Schistosoma mansoni protein kinase 0.0493 0.0967 0.0967
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0203 0.0203
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0544 0.1105 0.1105
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0698 0.1523 0.1523
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0347 0.1031
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0351 0.0581 0.1762
Echinococcus multilocularis hemicentin 1 0.0389 0.0683 0.0683
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0496 0.0974 0.0974
Loa Loa (eye worm) hypothetical protein 0.0543 0.1101 0.1101
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Toxoplasma gondii AGC kinase 0.0252 0.0312 0.0289
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0409 0.0739 0.0739
Echinococcus multilocularis rac serine:threonine kinase 0.0366 0.0622 0.0622
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0252 0.0312 0.0289
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni growth factor receptor-bound protein 0.0139 0.0006 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Brugia malayi Protein kinase domain containing protein 0.1066 0.2524 0.2524
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Echinococcus granulosus serine/threonine protein kinase 0.0366 0.0622 0.0622
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.031 0.0469 0.0469
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Onchocerca volvulus 0.0146 0.0025 0.0063
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0972 0.2268 0.2268
Echinococcus granulosus roundabout 2 0.0409 0.0739 0.0739
Trichomonas vaginalis CAMK family protein kinase 0.0282 0.0393 0.1174
Echinococcus granulosus protein kinase C gamma type 0.0451 0.0851 0.0851
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0181 0.0118 0.0094
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0304 0.0452 0.0338
Echinococcus multilocularis mitogen activated protein kinase 14 0.0355 0.0592 0.0592
Loa Loa (eye worm) AGC/PKA protein kinase 0.0252 0.0312 0.0312
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0147 0.0027 0.0057
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0455 0.0864 0.0864
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0349 0.0577 0.0554
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0416 0.0758 0.0758
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0351 0.0581 0.0581
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Trichomonas vaginalis STE family protein kinase 0.0304 0.0452 0.1359
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0187 0.0135 0.0111
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0969 0.2258 0.2258
Loa Loa (eye worm) hypothetical protein 0.0197 0.0163 0.0163
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0187 0.0135 0.0111
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0177 0.0108 0.0108
Schistosoma mansoni glutamate synthase 0.0351 0.0581 0.0581
Echinococcus multilocularis neurogenic locus protein delta 0.0418 0.0763 0.0763
Onchocerca volvulus 0.0249 0.0305 0.1343
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0192 0.0148 0.0148
Loa Loa (eye worm) casein kinase 0.0402 0.072 0.072
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0698 0.1523 0.1523
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0444 0.0444
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0262 0.034 0.1821
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Plasmodium falciparum serine/threonine protein kinase KIN 0.0174 0.0101 0.0077
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0238 0.0238
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0489 0.0955 0.0955
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0187 0.0135 0.0111
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0644 0.1377 0.1377
Giardia lamblia Kinase, PLK 0.0603 0.1266 0.3671
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0644 0.1377 0.1377
Echinococcus multilocularis mitogen activated protein kinase 14 0.0355 0.0592 0.0592
Plasmodium falciparum NIMA related kinase 1 0.0304 0.0452 0.0429
Plasmodium vivax calcium-dependent protein kinase, putative 0.0225 0.0238 0.0122
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus protein kinase shaggy 0.0287 0.0407 0.0407
Brugia malayi glutamate synthase 0.0351 0.0581 0.0581
Echinococcus granulosus casein kinase I alpha 0.0242 0.0286 0.0286
Schistosoma mansoni cell adhesion molecule 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0167 0.0081 0.0081
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0341 0.0555 0.0555
Echinococcus granulosus basement membrane specific heparan sulfate 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.1131 0.2698 0.2698
Brugia malayi Hr1 repeat family protein 0.0649 0.1389 0.1389
Echinococcus multilocularis N chimaerin 0.0167 0.0081 0.0081
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0355 0.0592 0.0569
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0409 0.0739 0.0739
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Giardia lamblia Kinase, CMGC CDK 0.0265 0.0347 0.07
Plasmodium vivax glycogen synthase kinase 3, putative 0.0287 0.0407 0.0292
Loa Loa (eye worm) hypothetical protein 0.0192 0.0148 0.0148
Echinococcus multilocularis dual specificity 0.031 0.0469 0.0469
Onchocerca volvulus 0.0412 0.0747 0.3364
Schistosoma mansoni protein kinase 0.0819 0.1851 0.1851
Leishmania major protein kinase, putative 0.0225 0.0238 0.0215
Entamoeba histolytica protein kinase, putative 0.0204 0.0182 0.0931
Loa Loa (eye worm) thyroid receptor interactor 0.0228 0.0247 0.0247
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0242 0.0286 0.0286
Trypanosoma cruzi cdc2-related kinase 3 0.0265 0.0347 0.0324
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0635 0.1353 0.1353
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0698 0.1523 0.1523
Entamoeba histolytica PH domain containing protein kinase, putative 0.0366 0.0622 0.3409
Loa Loa (eye worm) hypothetical protein 0.031 0.0469 0.0469
Echinococcus multilocularis C type lectin domian containing protein 0.0713 0.1563 0.1563
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0273 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0429 0.0793 0.0793
Trichomonas vaginalis CMGC family protein kinase 0.0343 0.0558 0.169
Toxoplasma gondii kringle domain-containing protein 0.025 0.0306 0.0282
Brugia malayi Furin-like cysteine rich region family protein 0.0775 0.1733 0.1733
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Entamoeba histolytica hypothetical protein 0.0429 0.0792 0.4366
Echinococcus granulosus casein kinase I alpha 0.0242 0.0286 0.0286
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0366 0.0622 0.06
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0355 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Echinococcus multilocularis serine:threonine protein kinase N2 0.0649 0.1389 0.1389
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Schistosoma mansoni laminin gamma-3 chain 0.0418 0.0763 0.0763
Brugia malayi Immunoglobulin domain containing protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis protein jagged 1 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Plasmodium vivax casein kinase 1, putative 0.0242 0.0286 0.017
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0452 0.0855 0.0855
Brugia malayi Protein kinase domain containing protein 0.0787 0.1765 0.1765
Loa Loa (eye worm) hypothetical protein 0.0266 0.0349 0.0349
Schistosoma mansoni peroxidasin 0.0212 0.0204 0.0204
Plasmodium vivax apical sushi protein, putative 0.0713 0.1563 0.1462
Schistosoma mansoni atypical protein kinase C 0.0651 0.1396 0.1396
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0191 0.0147 0.0029
Loa Loa (eye worm) hypothetical protein 0.1087 0.2579 0.2579
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0347 0.0347
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0273 0.0368 0.0345
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1323 0.3222 0.3205
Loa Loa (eye worm) TK protein kinase 0.0583 0.121 0.121
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1323 0.3222 1
Schistosoma mansoni tyrosine kinase 0.054 0.1095 0.1095
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Loa Loa (eye worm) hypothetical protein 0.0802 0.1807 0.1807
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0121 0.0121
Trypanosoma brucei trypanothione reductase 0.3819 1 1
Brugia malayi basement membrane proteoglycan precursor 0.0212 0.0203 0.0203
Brugia malayi Cyclin, N-terminal domain containing protein 0.0786 0.1763 0.1763
Plasmodium falciparum cysteine repeat modular protein 1 0.025 0.0306 0.0282
Echinococcus granulosus neurogenic locus protein delta 0.0418 0.0763 0.0763
Onchocerca volvulus Serine\/threonine kinase homolog 0.0366 0.0622 0.2791
Echinococcus granulosus glutamate synthase 0.0351 0.0581 0.0581
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis roundabout 2 0.0409 0.0739 0.0739
Echinococcus granulosus Protein kinase C brain isozyme 0.0544 0.1105 0.1105
Brugia malayi Disorganized muscle protein 1 0.0177 0.0108 0.0108
Schistosoma mansoni protein kinase 0.0591 0.1233 0.1233
Echinococcus granulosus rho-associated protein kinase 1 0.0726 0.1598 0.1598
Trichomonas vaginalis CMGC family protein kinase 0.031 0.0469 0.1412
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0603 0.1266 0.1266
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0819 0.1851 0.1851
Echinococcus granulosus dual specificity 0.031 0.0469 0.0469
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.1065 0.2519 0.2519
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Brugia malayi Immunoglobulin I-set domain containing protein 0.0212 0.0203 0.0203
Brugia malayi Myb-like DNA-binding domain containing protein 0.0177 0.0108 0.0108
Echinococcus granulosus serine:threonine protein kinase 3 0.0573 0.1184 0.1184
Echinococcus multilocularis cyclin dependent kinase 1 0.0265 0.0347 0.0347
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0486 0.0946 0.0946
Brugia malayi Immunoglobulin I-set domain containing protein 0.0409 0.0739 0.0739
Trichomonas vaginalis CMGC family protein kinase 0.02 0.0171 0.0481
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0365 0.062 0.062
Schistosoma mansoni serine/threonine protein kinase 0.0265 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0146 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.025 0.0306 0.0306
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0389 0.0683 0.0683
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0343 0.0558 0.0536
Trichomonas vaginalis CAMK family protein kinase 0.0603 0.1266 0.3896
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0276 0.0377 0.0377
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0691 0.1505 0.1505
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0969 0.2258 0.2258
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0249 0.0305 0.0282
Schistosoma mansoni sulfide quinone reductase 0.0351 0.0581 0.0581
Echinococcus granulosus titin 0.0177 0.0108 0.0108
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0189 0.014 0.0694
Loa Loa (eye worm) hypothetical protein 0.0174 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0319 0.0493 0.0493
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0225 0.0238 0.0215
Echinococcus granulosus cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0249 0.0305 0.0305
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Echinococcus multilocularis 0.0177 0.0108 0.0108
Echinococcus granulosus contactin 0.0409 0.0739 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0135 0.0135
Echinococcus granulosus insulin receptor 0.0671 0.145 0.145
Loa Loa (eye worm) AGC/PKN protein kinase 0.0649 0.1389 0.1389
Onchocerca volvulus 0.0177 0.0108 0.0442
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0351 0.0581 0.0581
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0392 0.0693 0.0693
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0179 0.0113 0.0113
Loa Loa (eye worm) animal heme peroxidase 0.0177 0.0108 0.0108
Trichomonas vaginalis glutathione reductase, putative 0.1323 0.3222 1
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0287 0.0407 0.0384
Plasmodium vivax glutathione reductase, putative 0.3819 1 1
Loa Loa (eye worm) CAMK protein kinase 0.0271 0.0362 0.0362
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0418 0.0763 0.0763
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Brugia malayi Protein kinase domain containing protein 0.0322 0.0503 0.0503
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0189 0.014 0.0694
Trichomonas vaginalis CMGC family protein kinase 0.0187 0.0135 0.0367
Brugia malayi Protein kinase domain containing protein 0.0366 0.0622 0.0622
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0225 0.0238 0.0238
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0787 0.1765 0.1765
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0511 0.1015 0.1015
Echinococcus multilocularis calcium dependent protein kinase 0.0152 0.0039 0.0039
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0972 0.2268 0.2268
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0262 0.034 0.1821
Brugia malayi Heparan sulfate 0.0212 0.0203 0.0203
Plasmodium vivax protein kinase Crk2 0.0265 0.0347 0.0232
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni cell adhesion molecule 0.0212 0.0203 0.0203
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0178 0.011 0.011
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0351 0.0581 0.0559
Brugia malayi Immunoglobulin I-set domain containing protein 0.0409 0.0739 0.0739
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0349 0.0577 0.0554
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0409 0.0739 0.0739
Brugia malayi Prion-like- 0.0389 0.0683 0.0683
Brugia malayi hypothetical protein 0.0718 0.1578 0.1578
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Echinococcus granulosus protein tyrosine kinase 0.0644 0.1376 0.1376
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Leishmania major protein kinase, putative 0.0262 0.034 0.0317
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Onchocerca volvulus 0.0713 0.1563 0.7093
Brugia malayi Protein kinase domain containing protein 0.0432 0.0802 0.0802
Schistosoma mansoni disulfide oxidoreductase 0.0351 0.0581 0.0581
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0252 0.0312 0.0289
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0167 0.0081 0.0081
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0351 0.0581 0.0581
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0397 0.0397
Entamoeba histolytica protein kinase, putative 0.0652 0.1399 0.7779
Echinococcus granulosus Glutaredoxin protein 5 0.0276 0.0377 0.0377
Schistosoma mansoni septate junction protein 0.0389 0.0683 0.0683
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0265 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase 0.0343 0.056 0.056
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0223 0.0234 0.0677
Giardia lamblia Kinase, AGC AKT 0.0261 0.0337 0.0666
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0212 0.0203 0.0203
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0323 0.0504 0.0504
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0343 0.0558 0.0536
Brugia malayi Protein kinase domain containing protein 0.0652 0.1399 0.1399
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Leishmania major hypothetical protein, conserved 0.025 0.0306 0.0282
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Loa Loa (eye worm) AUR protein kinase 0.0262 0.034 0.034
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0603 0.1266 0.1245
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0252 0.0312 0.0312
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0024 0.004
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0242 0.0286 0.0286
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0336 0.0541 0.0541
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Toxoplasma gondii thioredoxin reductase 0.3819 1 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0198 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0252 0.0312 0.0312
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Schistosoma mansoni cell polarity protein 0.0418 0.0763 0.0763
Giardia lamblia High cysteine protein 0.0418 0.0763 0.2044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3222
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0755 0.1679 0.1679
Toxoplasma gondii casein kinase I 0.0242 0.0286 0.0262
Echinococcus granulosus protein jagged 1 0.0418 0.0763 0.0763
Trypanosoma cruzi cdc2-related kinase 3 0.0265 0.0347 0.0324
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Onchocerca volvulus Neurogenic locus notch homolog 0.0418 0.0763 0.3435
Echinococcus granulosus mitogen activated protein kinase 14 0.0355 0.0592 0.0592
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0169 0.0086 0.0086
Brugia malayi Prion-like- 0.0177 0.0108 0.0108
Echinococcus granulosus mitogen activated protein kinase 0.0187 0.0135 0.0135
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0187 0.0135 0.0135
Echinococcus multilocularis expressed conserved protein 0.0188 0.0138 0.0138
Echinococcus granulosus casein kinase I gamma 0.0476 0.092 0.092
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.0855 0.0855
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1323 0.3222 1
Echinococcus granulosus protein jagged 1 0.0418 0.0763 0.0763
Echinococcus granulosus CDC7 cell division cycle 7 0.02 0.0171 0.0171
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0252 0.0312 0.0289
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0177 0.0108 0.0108
Echinococcus multilocularis serine:threonine protein kinase N2 0.0289 0.0414 0.0414
Echinococcus multilocularis myosin iiia 0.0189 0.014 0.014
Schistosoma mansoni serine/threonine protein kinase 0.1066 0.2524 0.2524
Echinococcus multilocularis protein jagged 2 0.0418 0.0763 0.0763
Onchocerca volvulus 0.0177 0.0108 0.0442
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1323 0.3222 1
Loa Loa (eye worm) TK/EGFR protein kinase 0.0775 0.1733 0.1733
Echinococcus granulosus insulin growth factor binding 0.0177 0.0108 0.0108
Echinococcus granulosus slit 2 protein 0.0468 0.0897 0.0897
Plasmodium falciparum casein kinase 1 0.0242 0.0286 0.0262
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1323 0.3222 0.3205
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.0558 0.0558
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0252 0.0312 0.0289
Loa Loa (eye worm) thioredoxin reductase 0.3819 1 1
Brugia malayi Cam kinase protein 1 0.0225 0.0238 0.0238
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0146 0.0025 0.0046
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1323 0.3222 0.3205
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0323 0.0504 0.0504
Trypanosoma brucei protein kinase, putative 0.0203 0.018 0.0156
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0343 0.0558 0.0536
Echinococcus multilocularis protein kinase shaggy 0.0287 0.0407 0.0407
Trypanosoma brucei SNF1-related protein kinases, putative 0.0174 0.0101 0.0077
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0188 0.0138 0.0114
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0351 0.0581 0.1762
Brugia malayi Protein kinase domain 0.0192 0.0148 0.0148
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0787 0.1765 0.1765
Echinococcus granulosus serine:threonine protein kinase N2 0.0649 0.1389 0.1389
Giardia lamblia Kinase, CDC7 0.02 0.0171 0.0131
Trypanosoma cruzi NADH dehydrogenase, putative 0.0351 0.0581 0.0559
Brugia malayi Protein kinase domain containing protein 0.0265 0.0347 0.0347
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0287 0.0407 0.0407
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0249 0.0305 0.0282
Leishmania major protein kinase, putative 0.0189 0.014 0.0116
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Loa Loa (eye worm) cyclin C 0.157 0.3892 0.3892
Echinococcus multilocularis cyclin dependent kinase 5 0.0265 0.0347 0.0347
Echinococcus granulosus tissue type plasminogen activator 0.025 0.0306 0.0306
Brugia malayi ephrin receptor 1 precursor 0.014 0.0008 0.0008
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0257 0.0325 0.0325
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0524 0.1052 0.1052
Echinococcus granulosus serine:threonine protein kinase N2 0.0289 0.0414 0.0414
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.02 0.0171 0.0481
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Onchocerca volvulus 0.0146 0.0025 0.0063
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Schistosoma mansoni nephrin 0.0895 0.2059 0.2059
Trypanosoma brucei NADH dehydrogenase 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Echinococcus multilocularis Immunoglobulin 0.0698 0.1523 0.1523
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0351 0.0581 0.0581
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0192 0.0148 0.0148
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0359 0.0603 0.0603
Trypanosoma cruzi NADH dehydrogenase, putative 0.0351 0.0581 0.0559
Schistosoma mansoni glutamate synthase 0.0351 0.0581 0.0581
Brugia malayi EGF-like domain containing protein 0.0468 0.0897 0.0897
Onchocerca volvulus 0.0177 0.0108 0.0442
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0283 0.0397 0.0397
Echinococcus multilocularis peroxidasin 0.0389 0.0685 0.0685
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0343 0.0558 0.0536
Brugia malayi Protein kinase domain containing protein 0.0713 0.1565 0.1565
Onchocerca volvulus Putative titin 0.0177 0.0108 0.0442
Onchocerca volvulus 0.0146 0.0025 0.0063
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0273 0.0368 0.0345
Echinococcus multilocularis dual specificity 0.031 0.0469 0.0469
Leishmania major hypothetical protein, conserved 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0416 0.0758 0.0758
Schistosoma mansoni serine/threonine protein kinase 0.031 0.0469 0.0469
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0325 0.096
Loa Loa (eye worm) hypothetical protein 0.0249 0.0305 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0171 0.0171
Trichomonas vaginalis AGC family protein kinase 0.0382 0.0666 0.2025
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0174 0.0101 0.0101
Trichomonas vaginalis STE family protein kinase 0.0189 0.014 0.0385
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0197 0.0163 0.0163
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Onchocerca volvulus 0.0177 0.0108 0.0442
Echinococcus granulosus activin receptor type 0.0146 0.0024 0.0024
Echinococcus multilocularis tyrosine protein kinase Abl 0.021 0.0197 0.0197
Echinococcus granulosus dual specificity 0.031 0.0469 0.0469
Trypanosoma brucei rac serine-threonine kinase, putative 0.0652 0.1399 0.1378
Onchocerca volvulus 0.0178 0.011 0.0449
Loa Loa (eye worm) TK/ABL protein kinase 0.0146 0.0025 0.0025
Brugia malayi protein kinase C II. 0.0455 0.0864 0.0864
Schistosoma mansoni tyrosine kinase 0.0671 0.145 0.145
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0691 0.1505 0.1505
Echinococcus granulosus dual specificity 0.031 0.0469 0.0469
Brugia malayi Protein kinase domain containing protein 0.1001 0.2346 0.2346
Schistosoma mansoni septate junction protein 0.0212 0.0203 0.0203
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1323 0.3222 0.3205
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0197 0.0163 0.0163
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0179 0.0113 0.0113
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0278 0.0383 0.0359
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0349 0.0577 0.0577
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0174 0.0101 0.0077
Echinococcus multilocularis tyrosine protein kinase HCK 0.0204 0.0182 0.0182
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0265 0.0347 0.0324
Echinococcus granulosus tyrosine kinase 0.0278 0.0383 0.0383
Schistosoma mansoni protein kinase 0.0262 0.034 0.034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0718 0.1578 0.1578
Echinococcus granulosus tyrosine protein kinase Src42A 0.0341 0.0555 0.0555
Loa Loa (eye worm) Notch2 0.0418 0.0763 0.0763
Loa Loa (eye worm) TK/EPH protein kinase 0.0255 0.0319 0.0319
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0165 0.0075 0.0075
Echinococcus granulosus lachesin 0.0389 0.0683 0.0683
Giardia lamblia Kinase, STE STE20 0.0192 0.0148 0.0057
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Brugia malayi Cadherin domain containing protein 0.0418 0.0763 0.0763
Trypanosoma brucei cdc2-related kinase 1 0.0265 0.0347 0.0324
Loa Loa (eye worm) hypothetical protein 0.0518 0.1034 0.1034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Entamoeba histolytica casein kinase, putative 0.0242 0.0286 0.1513
Entamoeba histolytica protein kinase, putative 0.0185 0.0131 0.0641
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0255 0.0319 0.0319
Echinococcus granulosus dual specificity 0.0273 0.0368 0.0368
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.031 0.0469 0.0469
Loa Loa (eye worm) hypothetical protein 0.0409 0.0739 0.0739
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1323 0.3222 0.3222
Echinococcus multilocularis c Jun NH2 terminal kinase 0.059 0.1229 0.1229
Trypanosoma brucei hypothetical protein, conserved 0.0351 0.0581 0.0559
Loa Loa (eye worm) hypothetical protein 0.0249 0.0305 0.0305
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1323 0.3222 0.2803
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0787 0.1765 0.8016
Brugia malayi casein kinase I 0.0242 0.0286 0.0286
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0819 0.1851 0.1851
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0252 0.0312 0.0289
Brugia malayi intracellular kinase 0.0287 0.0407 0.0407
Trichomonas vaginalis CK1 family protein kinase 0.0242 0.0286 0.0839
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0287 0.0407 0.0384
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0409 0.0739 0.0739
Trichomonas vaginalis AGC family protein kinase 0.0182 0.0121 0.0324
Brugia malayi Immunoglobulin I-set domain containing protein 0.0197 0.0163 0.0163
Trypanosoma cruzi polo-like protein kinase, putative 0.0603 0.1266 0.1245
Echinococcus multilocularis protein kinase c epsilon type 0.0455 0.0864 0.0864
Echinococcus granulosus defective proboscis extension response 0.0698 0.1523 0.1523
Echinococcus granulosus titin 0.0271 0.0362 0.0362
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0249 0.0305 0.0282
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0283 0.0397 0.0397
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0407 0.2196
Echinococcus granulosus thioredoxin glutathione reductase 0.3819 1 1
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.088 0.2017 0.2017
Leishmania major casein kinase II, putative 0.0223 0.0234 0.021
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.043 0.0796 0.0796
Onchocerca volvulus Netrin receptor homolog 0.0241 0.0283 0.1244
Schistosoma mansoni protein kinase 0.0242 0.0286 0.0286
Schistosoma mansoni tyrosine kinase 0.0387 0.068 0.068
Onchocerca volvulus 0.0644 0.1377 0.6243
Echinococcus granulosus neuroglian 0.0409 0.0739 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0476 0.092 0.092
Trichomonas vaginalis AGC family protein kinase 0.0304 0.0452 0.1359
Echinococcus multilocularis mitogen activated protein kinase 11 0.0355 0.0592 0.0592
Echinococcus granulosus tyrosine protein kinase Src42A 0.0208 0.0191 0.0191
Trypanosoma cruzi trypanothione reductase, putative 0.1323 0.3222 0.3205
Trichomonas vaginalis glutamate synthase, putative 0.0351 0.0581 0.1762
Entamoeba histolytica disulphide oxidoreductase, putative 0.0351 0.0581 0.3178
Brugia malayi Protein kinase domain containing protein 0.0671 0.145 0.145
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0407 0.2196
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0406 0.073 0.073
Schistosoma mansoni serine/threonine protein kinase 0.059 0.1229 0.1229
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Echinococcus granulosus neurogenic locus notch protein 4 0.0418 0.0763 0.0763
Plasmodium falciparum casein kinase 2, alpha subunit 0.0223 0.0234 0.021
Echinococcus granulosus delta-like protein 1 0.0418 0.0763 0.0763
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0323 0.0505 0.0505
Brugia malayi Protein kinase domain containing protein 0.0182 0.0121 0.0121
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Onchocerca volvulus 0.0418 0.0763 0.3435
Brugia malayi serine/threonine-protein kinase PAK 7 0.0518 0.1034 0.1034
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0351 0.0581 0.0559
Echinococcus granulosus C type lectin domian containing protein 0.0713 0.1563 0.1563
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0351 0.0581 0.0581
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0181 0.0118 0.0094
Entamoeba histolytica protein kinase, putative 0.0273 0.0368 0.1977
Echinococcus multilocularis protein tyrosine kinase 0.0644 0.1376 0.1376
Loa Loa (eye worm) AGC/PKG protein kinase 0.0188 0.0138 0.0138
Schistosoma mansoni tyrosine kinase 0.054 0.1095 0.1095
Echinococcus multilocularis serine:threonine protein kinase 38 0.0359 0.0603 0.0603
Echinococcus multilocularis casein kinase I alpha 0.0242 0.0286 0.0286
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0174 0.0101 0.0077
Echinococcus granulosus epidermal growth factor receptor 0.0775 0.1733 0.1733
Loa Loa (eye worm) CDC7 protein kinase 0.02 0.0171 0.0171
Trichomonas vaginalis AGC family protein kinase 0.0376 0.0648 0.1971
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Onchocerca volvulus 0.02 0.0171 0.0731
Onchocerca volvulus Slit protein homolog 0.0468 0.0897 0.4051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.0362 0.0362
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0108 0.0108
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0382 0.0666 0.0666
Brugia malayi Protein kinase domain containing protein 0.0146 0.0025 0.0025
Onchocerca volvulus 0.0726 0.1598 0.7255
Toxoplasma gondii histone kinase SNF1, putative 0.0174 0.0101 0.0077
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.0444 0.0444
Entamoeba histolytica protein kinase domain containing protein 0.0452 0.0855 0.472
Brugia malayi serine/threonine protein kinase 6 0.0262 0.034 0.034
Trichomonas vaginalis CK1 family protein kinase 0.0242 0.0286 0.0839
Echinococcus granulosus cyclin dependent kinase 1 0.0265 0.0347 0.0347
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0174 0.0101 0.0077
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0189 0.014 0.0116
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0273 0.0368 0.0345
Giardia lamblia Kinase, CAMK CAMKL 0.0191 0.0147 0.0052
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0252 0.0312 0.0289
Schistosoma mansoni protein kinase 0.0969 0.2258 0.2258
Entamoeba histolytica protein kinase, putative 0.016 0.0063 0.0259
Echinococcus granulosus tyrosine protein kinase otk 0.0389 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0713 0.1565 0.1565
Echinococcus multilocularis expressed protein 0.0185 0.0131 0.0131
Plasmodium falciparum glycogen synthase kinase 3 0.0287 0.0407 0.0384
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1323 0.3222 0.3222
Brugia malayi protein unc-22 0.0271 0.0362 0.0362
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0252 0.0312 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0225 0.0238 0.0691
Entamoeba histolytica protein kinase, putative 0.0185 0.0131 0.0641
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0212 0.0203 0.0203
Entamoeba histolytica protein kinase domain containing protein 0.0273 0.0368 0.1977
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1217
Schistosoma mansoni titin 0.0177 0.0108 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0603 0.0603
Schistosoma mansoni cell adhesion molecule 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0448 0.0844 0.0844
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0108 0.0108
Schistosoma mansoni serine/threonine protein kinase 0.0603 0.1266 0.1266
Schistosoma mansoni ste20-related kinase 0.0458 0.0871 0.0871
Loa Loa (eye worm) SRC-1 0.0341 0.0555 0.0555
Echinococcus multilocularis serine:threonine protein kinase N2 0.0359 0.0603 0.0603
Schistosoma mansoni protein kinase 0.0192 0.0148 0.0148
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1323 0.3222 0.2803
Echinococcus granulosus neural cadherin 0.0418 0.0763 0.0763
Brugia malayi Protein kinase domain containing protein 0.02 0.0171 0.0171
Schistosoma mansoni hypothetical protein 0.0418 0.0763 0.0763
Onchocerca volvulus 0.0177 0.0108 0.0442
Echinococcus multilocularis insulin receptor 0.0671 0.145 0.145
Entamoeba histolytica cell division protein kinase 2, putative 0.0282 0.0393 0.2115
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Echinococcus multilocularis epidermal growth factor receptor 0.0775 0.1733 0.1733
Echinococcus multilocularis dual specificity 0.031 0.0469 0.0469
Echinococcus multilocularis dual specificity protein kinase clk2 0.0343 0.0558 0.0558
Plasmodium falciparum apical sushi protein 0.0713 0.1563 0.1542
Echinococcus multilocularis serine:threonine protein kinase 3 0.0573 0.1184 0.1184
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.021 0.0197 0.0197
Echinococcus multilocularis CDC7 cell division cycle 7 0.02 0.0171 0.0171
Loa Loa (eye worm) AGC/PKA protein kinase 0.0252 0.0312 0.0312
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1323 0.3222 0.3205
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0713 0.1565 0.1565
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0351 0.0581 0.0581
Loa Loa (eye worm) hypothetical protein 0.0713 0.1563 0.1563
Onchocerca volvulus 0.031 0.0469 0.2092
Schistosoma mansoni protein kinase 0.0969 0.2258 0.2258
Schistosoma mansoni tyrosine kinase 0.021 0.0197 0.0197
Brugia malayi hypothetical protein 0.0713 0.1563 0.1563
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0389 0.0683 0.3073
Plasmodium falciparum calcium-dependent protein kinase 3 0.0225 0.0238 0.0215
Entamoeba histolytica hypothetical protein 0.0273 0.0368 0.1977
Loa Loa (eye worm) hypothetical protein 0.0877 0.2008 0.2008
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0351 0.0581 0.0559
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.025 0.0305 0.0305
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.3819 1 1
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0518 0.1034 0.1034
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0187 0.0135 0.0111
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0187 0.0135 0.0111
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0212 0.0203 0.0203
Brugia malayi Leucine Rich Repeat family protein 0.0178 0.011 0.011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0269 0.0358 0.1921
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0347 0.1031
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0078 0.0078
Brugia malayi Calcium binding EGF domain containing protein 0.0418 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis netrin receptor unc 5 0.0276 0.0378 0.0378
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0252 0.0312 0.0289
Schistosoma mansoni kinase 0.0644 0.1377 0.1377
Echinococcus multilocularis cyclin dependent kinase 0.0265 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0177 0.0108 0.0108
Giardia lamblia Kinase, AGC PKA 0.0252 0.0312 0.0587
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Trichomonas vaginalis apoptosis inducing factor, putative 0.0351 0.0581 0.1762
Leishmania major protein kinase A catalytic subunit 0.0252 0.0312 0.0289
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0309 0.0466 0.1403
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0174 0.0101 0.0077
Loa Loa (eye worm) hypothetical protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0197 0.0163 0.0163
Plasmodium vivax ferrodoxin reductase, putative 0.0351 0.0581 0.0469
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0169 0.0086 0.0063
Echinococcus granulosus protein jagged 2 0.0418 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0603 0.0603
Trypanosoma brucei cdc2-related kinase 3 0.0265 0.0347 0.0324
Echinococcus granulosus fibropellin Ia 0.0418 0.0763 0.0763
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0341 0.0555 0.0555
Echinococcus multilocularis lachesin 0.0389 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0547 0.1113 0.1113
Onchocerca volvulus 0.0146 0.0025 0.0063
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0178 0.011 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Loa Loa (eye worm) hypothetical protein 0.0389 0.0683 0.0683
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0232 0.0258 0.0258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0362 0.0362
Entamoeba histolytica protein kinase, putative 0.0192 0.0148 0.074
Onchocerca volvulus 0.0713 0.1563 0.7093
Schistosoma mansoni nephrin related 0.0212 0.0203 0.0203
Echinococcus granulosus calcium dependent protein kinase 0.0152 0.0039 0.0039
Giardia lamblia Kinase, NEK 0.0304 0.0452 0.104
Brugia malayi map kinase activated protein kinase protein 2 0.088 0.2017 0.2017
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0167 0.0081 0.0081
Brugia malayi Variant SH3 domain containing protein 0.0167 0.0081 0.0081
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0359 0.0603 0.0603
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0188 0.0138 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0652 0.1399 0.4312
Echinococcus multilocularis epidermal growth factor receptor 0.054 0.1095 0.1095
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0493 0.0967 0.0967
Loa Loa (eye worm) glutathione reductase 0.3819 1 1
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.031 0.0469 0.0469
Onchocerca volvulus 0.0713 0.1563 0.7093
Loa Loa (eye worm) hypothetical protein 0.0468 0.0897 0.0897
Trichomonas vaginalis CMGC family protein kinase 0.02 0.0171 0.0481
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1323 0.3222 0.3205
Echinococcus multilocularis titin 0.0177 0.0108 0.0108
Echinococcus granulosus cyclin dependent kinase 9 0.0169 0.0086 0.0086
Loa Loa (eye worm) TK/FER protein kinase 0.0146 0.0025 0.0025
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.059 0.1229 0.1229
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0262 0.034 0.1821
Plasmodium falciparum glutathione reductase 0.1323 0.3222 0.3205
Echinococcus multilocularis raf serine:threonine protein kinase 0.0166 0.0078 0.0078
Entamoeba histolytica protein kinase, putative 0.016 0.0063 0.0259
Loa Loa (eye worm) hypothetical protein 0.0403 0.0722 0.0722
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0351 0.0581 0.0469
Schistosoma mansoni notch 0.0418 0.0763 0.0763
Brugia malayi GCC2 and GCC3 family protein 0.1131 0.2698 0.2698
Giardia lamblia Kinase, CMGC DYRK 0.031 0.0469 0.1096
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Schistosoma mansoni protein kinase 0.0969 0.2258 0.2258
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0483 0.0938 0.0938
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0189 0.014 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0389 0.0683 0.0683
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1323 0.3222 0.3205
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0351 0.0581 0.0581
Echinococcus granulosus growth factor receptor bound protein 2 0.0139 0.0006 0.0006
Echinococcus multilocularis cyclin dependent kinase 1 0.0265 0.0347 0.0347
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1323 0.3222 1
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0287 0.0407 0.0407
Echinococcus multilocularis slit 2 protein 0.0468 0.0897 0.0897
Schistosoma mansoni ephrin receptor 0.0216 0.0213 0.0213
Schistosoma mansoni hypothetical protein 0.0177 0.0108 0.0108
Echinococcus granulosus cyclin dependent kinase 5 0.0265 0.0347 0.0347
Echinococcus granulosus nephrin 0.0197 0.0163 0.0163
Echinococcus multilocularis activin receptor type 0.0146 0.0024 0.0024
Schistosoma mansoni tyrosine kinase 0.0775 0.1733 0.1733
Loa Loa (eye worm) hypothetical protein 0.1087 0.2579 0.2579
Echinococcus granulosus titin 0.0177 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0418 0.0763 0.0763
Entamoeba histolytica casein kinase, putative 0.0223 0.0234 0.1221
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0351 0.0581 0.0581
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0518 0.1034 0.1034
Schistosoma mansoni septate junction protein 0.0212 0.0203 0.0203
Trichomonas vaginalis AGC family protein kinase 0.0252 0.0312 0.0921
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Entamoeba histolytica protein kinase 2, putative 0.0349 0.0577 0.315
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0406 0.073 0.073
Brugia malayi Protein kinase domain containing protein 0.0819 0.1851 0.1851
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0225 0.0238 0.0122
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0212 0.0203 0.0203
Echinococcus granulosus roundabout 2 0.1107 0.2634 0.2634
Loa Loa (eye worm) AUR protein kinase 0.0262 0.034 0.034
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0448 0.0844 0.0844
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0177 0.0108 0.0108
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1323 0.3222 0.3141
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0366 0.0622 0.0622
Echinococcus multilocularis mitogen activated protein kinase 11 0.0355 0.0592 0.0592
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0185 0.0131 0.0107
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0341 0.0555 0.0555
Echinococcus multilocularis hemicentin 1 0.0389 0.0683 0.0683
Loa Loa (eye worm) TK/INSR protein kinase 0.0671 0.145 0.145
Loa Loa (eye worm) hypothetical protein 0.025 0.0306 0.0306
Schistosoma mansoni titin 0.0197 0.0163 0.0163
Brugia malayi EGF-like domain containing protein 0.0418 0.0763 0.0763
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0351 0.0581 0.1762
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0265 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0489 0.0955 0.0955
Trichomonas vaginalis AGC family protein kinase 0.0399 0.0712 0.2168
Schistosoma mansoni protein kinase 0.0146 0.0024 0.0024
Echinococcus granulosus ephrin type A receptor 4 A 0.0216 0.0213 0.0213
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0351 0.0581 0.3178
Trypanosoma cruzi casein kinase, putative 0.0242 0.0286 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.0448 0.0844 0.0844
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0342 0.0555 0.0555
Onchocerca volvulus 0.0713 0.1563 0.7093
Brugia malayi Prion-like- 0.0177 0.0108 0.0108
Echinococcus granulosus protein jagged 2 0.0418 0.0763 0.0763
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0351 0.0581 0.0581
Echinococcus granulosus cyclin dependent kinase 19 0.1066 0.2524 0.2524
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0482 0.0937 0.0937
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0351 0.0581 0.0581
Schistosoma mansoni hypothetical protein 0.0212 0.0203 0.0203
Loa Loa (eye worm) TK protein kinase 0.0204 0.0182 0.0182
Echinococcus multilocularis notch 0.0418 0.0763 0.0763
Brugia malayi Protein kinase domain containing protein 0.0255 0.0319 0.0319
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0242 0.0286 0.0286
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0496 0.0974 0.0974
Brugia malayi Sushi domain 0.0713 0.1563 0.1563
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1323 0.3222 0.3205
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0343 0.0558 0.0536
Onchocerca volvulus 0.0418 0.0763 0.3435
Trichomonas vaginalis CAMK family protein kinase 0.0174 0.0101 0.0263
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0242 0.0286 0.0262
Trypanosoma brucei aurora B kinase 0.0262 0.034 0.0317
Plasmodium falciparum cGMP-dependent protein kinase 0.0188 0.0138 0.0114
Toxoplasma gondii selenide, water dikinase 0.0351 0.0581 0.0559
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0698 0.1523 0.1523

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.66 uM Inhibitory concentration value against murine P-388 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human A-549 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon adenocarcinoma HT-29 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human MEL-28 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon carcinoma H-116 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against murine P-388 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human A-549 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon adenocarcinoma HT-29 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human MEL-28 tumor cell line ChEMBL. 15658869
IC50 (functional) = 3.66 uM Inhibitory concentration value against human colon carcinoma H-116 tumor cell line ChEMBL. 15658869

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 15658869
Homo sapiens ChEMBL23 15658869

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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