Detailed information for compound 313607

Basic information

Technical information
  • TDR Targets ID: 313607
  • Name: 2-(furan-2-yl)-7-pyridin-4-yl-[1,2,4]triazolo [5,1-f]pyrimidin-5-amine
  • MW: 278.269 | Formula: C14H10N6O
  • H donors: 1 H acceptors: 4 LogP: 1.1 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1nc(cc2n1nc(n2)c1ccco1)c1ccncc1
  • InChi: 1S/C14H10N6O/c15-14-17-10(9-3-5-16-6-4-9)8-12-18-13(19-20(12)14)11-2-1-7-21-11/h1-8H,(H2,15,17)
  • InChiKey: NHZYHGYDBWKPRJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-furyl)-7-(4-pyridyl)-[1,2,4]triazolo[5,1-f]pyrimidin-5-amine
  • [2-(2-furyl)-7-(4-pyridyl)-[1,2,4]triazolo[5,1-f]pyrimidin-5-yl]amine
  • 2-furan-2-yl-7-pyridin-4-yl-[1,2,4]triazolo[5,1-f]pyrimidin-5-amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Adenosine A2a receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus allatostatin A receptor Adenosine A2a receptor   410 aa 368 aa 22.6 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Adenosine A2a receptor   410 aa 346 aa 28.3 %
Echinococcus granulosus thyrotropin releasing hormone receptor Adenosine A2a receptor   410 aa 342 aa 23.1 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Adenosine A2a receptor   410 aa 342 aa 23.1 %
Onchocerca volvulus Adenosine A2a receptor   410 aa 337 aa 23.1 %
Schistosoma mansoni biogenic amine (5HT) receptor Adenosine A2a receptor   410 aa 399 aa 28.1 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Adenosine A2a receptor   410 aa 340 aa 27.9 %
Echinococcus multilocularis allatostatin A receptor Adenosine A2a receptor   410 aa 372 aa 22.8 %
Onchocerca volvulus Adenosine A2a receptor   410 aa 356 aa 23.9 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Adenosine A2a receptor   410 aa 352 aa 23.6 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Adenosine A2a receptor   410 aa 366 aa 25.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0261 0.0584 0.0583
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0229 0.0461 0.046
Brugia malayi Protein kinase domain containing protein 0.0612 0.1943 0.1943
Entamoeba histolytica protein kinase, putative 0.013 0.0078 0.0322
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0933 0.3187 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0084 0.0084
Onchocerca volvulus 0.0129 0.0073 0.026
Loa Loa (eye worm) AGC/PKG protein kinase 0.0174 0.0249 0.0249
Schistosoma mansoni hypothetical protein 0.0132 0.0084 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0249 0.0249
Schistosoma mansoni protein kinase 0.0174 0.0249 0.0249
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0533 0.0533
Echinococcus multilocularis NCK adaptor protein 0.0129 0.0075 0.0075
Onchocerca volvulus 0.0375 0.1028 0.3666
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0438 0.1272 0.1272
Schistosoma mansoni hypothetical protein 0.0151 0.0158 0.0158
Echinococcus granulosus contactin 0.0306 0.0759 0.0759
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.022 0.0427 0.0427
Loa Loa (eye worm) TK/FER protein kinase 0.0458 0.135 0.135
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0158 0.0158
Plasmodium falciparum calcium-dependent protein kinase 1 0.0204 0.0365 0.0277
Brugia malayi serine/threonine protein kinase 6 0.024 0.0505 0.0505
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Echinococcus multilocularis peroxidasin 0.0288 0.0688 0.0688
Brugia malayi MAP kinase sur-1 0.017 0.0231 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0633 0.0633
Schistosoma mansoni protein kinase 0.0881 0.2988 0.2988
Echinococcus multilocularis tyrosine protein kinase Blk 0.0258 0.0573 0.0573
Schistosoma mansoni serine/threonine kinase 0.0448 0.1309 0.1309
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.044 0.128 0.128
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0177 0.0177
Onchocerca volvulus 0.0132 0.0086 0.0307
Schistosoma mansoni protein kinase 0.0134 0.0091 0.0091
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0685 0.2228 0.2228
Plasmodium falciparum calcium-dependent protein kinase 5 0.0204 0.0365 0.0277
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0231 0.047 0.047
Brugia malayi Cyclin C 0.1451 0.5195 0.5195
Brugia malayi Protein kinase domain containing protein 0.0136 0.0101 0.0101
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0533 0.0446
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0262 0.0587 0.0587
Schistosoma mansoni hypothetical protein 0.0132 0.0084 0.0084
Mycobacterium tuberculosis Probable oxidoreductase 0.0933 0.3187 0.2803
Brugia malayi probable protein kinase 0.0538 0.1657 0.1657
Schistosoma mansoni laminin gamma-3 chain 0.0272 0.0627 0.0627
Echinococcus granulosus serine:threonine protein kinase 12 B 0.024 0.0505 0.0505
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0801 0.2675 0.2675
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0261 0.0584 0.0584
Onchocerca volvulus 0.0151 0.0158 0.0562
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0282 0.0666 0.058
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0988 0.3401 0.3401
Giardia lamblia Glutamate synthase 0.0248 0.0533 0.1055
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.1699 0.5331
Trypanosoma cruzi casein kinase, putative 0.022 0.0427 0.0425
Leishmania major hypothetical protein, conserved 0.0248 0.0533 0.0446
Echinococcus granulosus tyrosine protein kinase 0.0322 0.0822 0.0822
Entamoeba histolytica protein kinase, putative 0.0204 0.0365 0.1511
Loa Loa (eye worm) hypothetical protein 0.0175 0.025 0.025
Echinococcus multilocularis nervana 2 0.0251 0.0548 0.0548
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0478 0.1425 0.1425
Schistosoma mansoni hypothetical protein 0.0155 0.0175 0.0175
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3186
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0799 0.0799
Schistosoma mansoni titin 0.0132 0.0084 0.0084
Echinococcus multilocularis protein kinase c iota type 0.0581 0.1823 0.1823
Echinococcus granulosus N chimaerin 0.0154 0.0169 0.0169
Brugia malayi Immunoglobulin I-set domain containing protein 0.1378 0.491 0.491
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0159 0.019 0.01
Trypanosoma cruzi polo-like protein kinase, putative 0.0549 0.1699 0.1698
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0248 0.0533 0.0331
Schistosoma mansoni serine/threonine kinase 0.0327 0.0841 0.0841
Schistosoma mansoni adapter molecule crk 0.0127 0.0066 0.0066
Schistosoma mansoni protein kinase 0.0881 0.2988 0.2988
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0241 0.0507 0.0419
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0127 0.0066 0.0066
Echinococcus multilocularis netrin receptor unc 5 0.0214 0.0403 0.0403
Echinococcus granulosus insulin growth factor binding 0.0132 0.0084 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0507 0.1586
Schistosoma mansoni tyrosine kinase 0.0354 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0391 0.1089 0.1089
Trichomonas vaginalis AGC family protein kinase 0.0349 0.0925 0.29
Schistosoma mansoni cell adhesion molecule 0.0151 0.0158 0.0158
Schistosoma mansoni g1/s-specific cyclin C 0.1451 0.5195 0.5195
Onchocerca volvulus Slit protein homolog 0.0318 0.0804 0.2867
Trichomonas vaginalis AGC family protein kinase 0.024 0.0505 0.1582
Echinococcus multilocularis cyclin dependent kinase 1 0.0241 0.0507 0.0507
Trypanosoma cruzi casein kinase, delta isoform, putative 0.022 0.0427 0.0425
Onchocerca volvulus 0.0154 0.017 0.0606
Schistosoma mansoni nephrin related 0.0155 0.0175 0.0175
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0306 0.0759 0.0759
Brugia malayi serine/threonine kinase 12 0.024 0.0505 0.0505
Echinococcus multilocularis tyrosine protein kinase HCK 0.0189 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0282 0.0667 0.0667
Echinococcus granulosus twitchin 0.0718 0.2357 0.2357
Loa Loa (eye worm) AUR protein kinase 0.024 0.0505 0.0505
Echinococcus granulosus casein kinase I alpha 0.022 0.0427 0.0427
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0504 0.1525 0.1525
Trichomonas vaginalis mercuric reductase, putative 0.0933 0.3187 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.0249 0.0249
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0002 0.0002
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0276 0.0643 0.0443
Onchocerca volvulus 0.0136 0.0101 0.0358
Loa Loa (eye worm) hypothetical protein 0.0288 0.0688 0.0688
Onchocerca volvulus 0.0132 0.0084 0.03
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.011 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0272 0.0627 0.0627
Echinococcus granulosus epidermal growth factor receptor 0.0504 0.1525 0.1525
Brugia malayi Fibronectin type III domain containing protein 0.0539 0.1663 0.1663
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0229 0.0461 0.0373
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0312 0.0781 0.078
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0306 0.0759 0.0759
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0272 0.0627 0.2237
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0229 0.0461 0.0373
Brugia malayi Prion-like- 0.0287 0.0686 0.0686
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3124
Schistosoma mansoni tyrosine kinase 0.0436 0.1264 0.1264
Brugia malayi Heparan sulfate 0.0155 0.0175 0.0175
Onchocerca volvulus 0.013 0.0078 0.0278
Brugia malayi Protein kinase domain containing protein 0.0289 0.0695 0.0695
Plasmodium falciparum calcium-dependent protein kinase 3 0.0204 0.0365 0.0277
Brugia malayi EGF-like domain containing protein 0.0272 0.0627 0.0627
Brugia malayi casein kinase I 0.022 0.0427 0.0427
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0194 0.0327 0.0327
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0287 0.0686 0.0686
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0933 0.3187 0.3124
Trichomonas vaginalis STE family protein kinase 0.0174 0.0249 0.0775
Loa Loa (eye worm) hypothetical protein 0.0774 0.2573 0.2573
Onchocerca volvulus 0.0182 0.0278 0.0991
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Echinococcus multilocularis down syndrome cell adhesion 0.0132 0.0084 0.0084
Echinococcus granulosus mitogen activated protein kinase 11 0.0323 0.0824 0.0824
Entamoeba histolytica protein kinase, putative 0.0165 0.0213 0.088
Plasmodium falciparum casein kinase 1 0.022 0.0427 0.0339
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0168 0.0226 0.0226
Loa Loa (eye worm) TK/ABL protein kinase 0.0136 0.0101 0.0101
Brugia malayi Protein kinase domain containing protein 0.0407 0.1152 0.1152
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0174 0.0249 0.0249
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.0091 0.0378
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1914 0.6989 0.6989
Schistosoma mansoni protein kinase 0.024 0.0505 0.0505
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0155 0.0175 0.0175
Loa Loa (eye worm) notch protein 0.0272 0.0627 0.0627
Entamoeba histolytica protein kinase domain containing protein 0.0411 0.1167 0.4828
Echinococcus granulosus neuroglian 0.0306 0.0759 0.0759
Onchocerca volvulus 0.0132 0.0084 0.03
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0533 0.0532
Echinococcus multilocularis mitogen activated protein kinase 3 0.017 0.0231 0.0231
Schistosoma mansoni protein kinase 0.0203 0.036 0.036
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0781 0.2447
Loa Loa (eye worm) TK protein kinase 0.0189 0.0307 0.0307
Schistosoma mansoni disulfide oxidoreductase 0.0248 0.0533 0.0533
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0262 0.0587 0.0587
Brugia malayi Protein kinase c protein 2 0.0234 0.0482 0.0482
Onchocerca volvulus 0.0136 0.0101 0.0358
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0204 0.0365 0.0365
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0318 0.0805 0.0608
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0933 0.3187 0.3186
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Brugia malayi Temporarily assigned gene name protein 59 0.0262 0.059 0.059
Loa Loa (eye worm) casein kinase 0.0366 0.0994 0.0994
Echinococcus multilocularis dual specificity 0.0282 0.0666 0.0666
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0171 0.0238 0.0236
Loa Loa (eye worm) hypothetical protein 0.0245 0.0524 0.0524
Trichomonas vaginalis glutathione reductase, putative 0.0933 0.3187 1
Schistosoma mansoni cell adhesion molecule 0.0155 0.0175 0.0175
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0407 0.1152 0.1152
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0933 0.3187 1
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0253 0.0553 0.0466
Trichomonas vaginalis AGC family protein kinase 0.0364 0.0985 0.3088
Schistosoma mansoni serine/threonine protein kinase 0.0152 0.0164 0.0164
Onchocerca volvulus 0.0217 0.0415 0.1478
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0249 0.0249
Plasmodium falciparum calcium-dependent protein kinase 2 0.0204 0.0365 0.0277
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0084 0.0084
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0442 0.1285 0.1285
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.024 0.0505 0.2091
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0332 0.0861 0.0861
Loa Loa (eye worm) one IG domain family member 0.0132 0.0084 0.0084
Echinococcus granulosus cyclin dependent kinase 0.0241 0.0507 0.0507
Brugia malayi Protein kinase domain containing protein 0.0327 0.0841 0.0841
Giardia lamblia Kinase, CMGC CK2 0.0203 0.036 0.047
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0159 0.019 0.01
Brugia malayi Protein kinase domain containing protein 0.0241 0.0507 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0461 0.0461
Trypanosoma cruzi cdc2-related kinase 1 0.0241 0.0507 0.0505
Schistosoma mansoni vav2 0.0169 0.0229 0.0229
Brugia malayi protein kinase C3,putative 0.032 0.0813 0.0813
Echinococcus multilocularis rac serine:threonine kinase 0.0333 0.0865 0.0865
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0641 0.2056 0.2056
Loa Loa (eye worm) TK/INSR protein kinase 0.0622 0.1982 0.1982
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0282 0.0666 0.0666
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0155 0.0175 0.0175
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0933 0.3187 0.3124
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Schistosoma mansoni glutamate synthase 0.0248 0.0533 0.0533
Trichomonas vaginalis CMGC family protein kinase 0.017 0.0231 0.0719
Loa Loa (eye worm) cyclin domain-containing protein 0.0724 0.2377 0.2377
Loa Loa (eye worm) hypothetical protein 0.0287 0.0686 0.0686
Entamoeba histolytica thioredoxin reductase, putative 0.0248 0.0533 0.2205
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0391 0.109 0.109
Echinococcus multilocularis fat cadherin tumor suppressor 0.0272 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0375 0.1028 0.1028
Echinococcus multilocularis cyclin dependent kinase 5 0.0241 0.0507 0.0507
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0204 0.0365 0.0277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0158 0.0158
Brugia malayi Serine/threonine-protein kinase SULU 0.0451 0.1321 0.1321
Schistosoma mansoni tyrosine kinase 0.0194 0.0327 0.0327
Brugia malayi protein unc-22 0.0217 0.0415 0.0415
Echinococcus granulosus serine/threonine protein kinase 0.0333 0.0865 0.0865
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0204 0.0365 0.0365
Echinococcus granulosus insulin receptor 0.0622 0.1982 0.1982
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0241 0.0507 0.0507
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0533 0.1668
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0287 0.0686 0.0686
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0666 0.2085
Brugia malayi Protein kinase domain containing protein 0.0911 0.3103 0.3103
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0169 0.0169
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3124
Brugia malayi EGF-like domain containing protein 0.0272 0.0627 0.0627
Echinococcus multilocularis twitchin 0.0198 0.0341 0.0341
Onchocerca volvulus 0.0136 0.0101 0.0358
Schistosoma mansoni tyrosine kinase 0.0622 0.1982 0.1982
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0933 0.3187 0.3124
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0933 0.3187 0.3124
Onchocerca volvulus 0.0502 0.1519 0.5418
Entamoeba histolytica serine/threonine protein kinase, putative 0.0549 0.1699 0.7032
Onchocerca volvulus 0.0261 0.0584 0.2084
Schistosoma mansoni nck2/grb4 0.0127 0.0066 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0537 0.1652 0.1652
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0641 0.2056 0.2056
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0933 0.3187 0.3041
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0458 0.135 0.135
Echinococcus multilocularis cyclin 0.0724 0.2377 0.2377
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Schistosoma mansoni slit 0.0132 0.0086 0.0086
Echinococcus multilocularis 0.0245 0.0524 0.0524
Schistosoma mansoni serine/threonine protein kinase 0.0988 0.3401 0.3401
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0533 0.0532
Schistosoma mansoni hypothetical protein 0.0132 0.0084 0.0084
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0237 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0227 0.0454 0.0454
Echinococcus granulosus protein kinase 0.0311 0.0777 0.0777
Plasmodium vivax glutathione reductase, putative 0.2692 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.0781 0.0781
Echinococcus multilocularis insulin receptor 0.0622 0.1982 0.1982
Brugia malayi Protein kinase domain containing protein 0.0393 0.1097 0.1097
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0136 0.0101 0.0101
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0745 0.2459 0.2459
Schistosoma mansoni septate junction protein 0.0287 0.0686 0.0686
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0248 0.0534 0.0532
Loa Loa (eye worm) protein kinase domain-containing protein 0.0433 0.125 0.125
Loa Loa (eye worm) hypothetical protein 0.0155 0.0175 0.0175
Echinococcus multilocularis serine:threonine protein kinase N2 0.0264 0.0595 0.0595
Schistosoma mansoni serine/threonine protein kinase 0.0801 0.2675 0.2675
Echinococcus multilocularis protein jagged 1 0.0272 0.0627 0.0627
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0136 0.0101 0.0416
Brugia malayi P38 map kinase family protein 2 0.0323 0.0824 0.0824
Trypanosoma cruzi trypanothione reductase, putative 0.0933 0.3187 0.3186
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0427 0.0427
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0933 0.3187 0.3124
Echinococcus multilocularis raf serine:threonine protein kinase 0.0152 0.0164 0.0164
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0533 0.0446
Schistosoma mansoni tyrosine kinase 0.0605 0.1918 0.1918
Echinococcus multilocularis lachesin 0.0287 0.0686 0.0686
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0261 0.0584 0.0498
Plasmodium falciparum apical sushi protein 0.0502 0.1519 0.1441
Echinococcus multilocularis tyrosine protein kinase otk 0.0287 0.0686 0.0686
Entamoeba histolytica protein kinase , putative 0.024 0.0505 0.2091
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.017 0.0231 0.0141
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0933 0.3187 1
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Echinococcus multilocularis growth factor receptor bound protein 2 0.0127 0.0066 0.0066
Schistosoma mansoni basigin related 0.0155 0.0175 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0214 0.0403 0.0403
Entamoeba histolytica protein kinase, putative 0.0146 0.0138 0.057
Echinococcus granulosus hemicentin 1 0.0287 0.0686 0.0686
Trichomonas vaginalis CAMK family protein kinase 0.0256 0.0566 0.1773
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0801 0.2675 0.2675
Echinococcus granulosus protein kinase shaggy 0.0261 0.0584 0.0584
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0248 0.0533 0.1055
Echinococcus granulosus casein kinase I delta 0.022 0.0427 0.0427
Echinococcus granulosus hypothetical protein 0.0245 0.0524 0.0524
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0533 0.0532
Echinococcus granulosus neurogenic locus notch protein 4 0.0272 0.0627 0.0627
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0248 0.0534 0.0447
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0204 0.0365 0.0277
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0537 0.1652 0.1652
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0154 0.017 0.0169
Echinococcus granulosus neural cadherin 0.0272 0.0628 0.0628
Echinococcus multilocularis Glutaredoxin protein 5 0.0251 0.0548 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3186
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.019 0.019
Brugia malayi Protein kinase domain containing protein 0.0669 0.2165 0.2165
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0159 0.019 0.0189
Schistosoma mansoni c4b-binding protein beta chain 0.0502 0.1519 0.1519
Echinococcus granulosus neurogenic locus protein delta 0.0272 0.0627 0.0627
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0666 0.2085
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0132 0.0084 0.0084
Brugia malayi Prion-like- 0.0132 0.0084 0.0084
Onchocerca volvulus Putative cubilin 0.0272 0.0627 0.2237
Entamoeba histolytica protein kinase 2, putative 0.0318 0.0805 0.3329
Echinococcus multilocularis CDC7 cell division cycle 7 0.0182 0.0278 0.0278
Echinococcus granulosus neurogenic locus notch protein 0.0272 0.0627 0.0627
Schistosoma mansoni basigin related 0.0155 0.0175 0.0175
Schistosoma mansoni neuroglian 0.0306 0.0759 0.0759
Entamoeba histolytica protein kinase, putative 0.0135 0.0097 0.04
Leishmania major protein kinase, putative 0.0171 0.0238 0.0148
Trypanosoma brucei aurora B kinase 0.024 0.0505 0.0418
Entamoeba histolytica protein kinase domain containing protein 0.0203 0.036 0.1488
Echinococcus multilocularis 0.0201 0.0354 0.0354
Echinococcus multilocularis fibropellin Ia 0.0272 0.0627 0.0627
Brugia malayi EGF-like domain containing protein 0.0272 0.0627 0.0627
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0316 0.0799 0.0799
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0258 0.0573 0.0573
Brugia malayi phosphoinositide-dependent protein kinase I 0.0165 0.0213 0.0213
Leishmania major protein kinase, putative 0.024 0.0505 0.0418
Giardia lamblia Kinase, STE STE20 0.0171 0.0238 0.006
Toxoplasma gondii casein kinase I 0.022 0.0427 0.0339
Onchocerca volvulus 0.0136 0.0101 0.0358
Brugia malayi Protein kinase domain containing protein 0.0669 0.2165 0.2165
Brugia malayi putative serine/threonine kinase SADA gamma 0.0159 0.019 0.019
Plasmodium vivax ferrodoxin reductase, putative 0.0248 0.0533 0.0331
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0174 0.0249 0.0249
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0248 0.0533 0.0446
Echinococcus multilocularis epidermal growth factor receptor 0.0725 0.2382 0.2382
Schistosoma mansoni protein kinase 0.045 0.1316 0.1316
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Echinococcus granulosus lachesin 0.0287 0.0686 0.0686
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0318 0.0805 0.0803
Brugia malayi Furin-like cysteine rich region family protein 0.0725 0.2382 0.2382
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0171 0.0238 0.0148
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Echinococcus granulosus delta-like protein 1 0.0272 0.0627 0.0627
Echinococcus multilocularis neurogenic locus notch protein 0.0272 0.0627 0.0627
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0933 0.3187 0.3186
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0312 0.0781 0.0696
Echinococcus multilocularis roundabout 2 0.0306 0.0759 0.0759
Echinococcus granulosus neuroglian 0.0652 0.21 0.21
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0533 0.1668
Giardia lamblia Kinase, AGC PKA 0.0229 0.0461 0.0813
Onchocerca volvulus 0.0502 0.1519 0.5418
Echinococcus multilocularis cyclin dependent kinase 1 0.0241 0.0507 0.0507
Echinococcus granulosus cyclin dependent kinase 5 0.0241 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Echinococcus granulosus Immunoglobulin 0.0155 0.0175 0.0175
Brugia malayi Disorganized muscle protein 1 0.0132 0.0084 0.0084
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0933 0.3187 0.3041
Loa Loa (eye worm) AGC/PKA protein kinase 0.0229 0.0461 0.0461
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0233 0.0477 0.0477
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0318 0.0805 0.072
Echinococcus multilocularis mitogen activated protein kinase 14 0.0323 0.0824 0.0824
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0533 0.0331
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0411 0.1167 0.1167
Trichomonas vaginalis STE family protein kinase 0.0276 0.0643 0.2015
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0163 0.0204 0.0204
Echinococcus granulosus cyclin dependent kinase 9 0.0118 0.003 0.003
Echinococcus multilocularis titin 0.0217 0.0415 0.0415
Brugia malayi Protein kinase domain containing protein 0.0136 0.0101 0.0101
Echinococcus granulosus tyrosine protein kinase Lyn 0.0383 0.1056 0.1056
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0333 0.0863 0.0863
Echinococcus granulosus fibroblast growth factor receptor 4 0.0374 0.1023 0.1023
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0294 0.0712 0.0712
Trypanosoma cruzi cdc2-related kinase 3 0.0241 0.0507 0.0505
Onchocerca volvulus 0.0132 0.0084 0.03
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0204 0.0365 0.0277
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0316 0.0799 0.0799
Brugia malayi EGF-like domain containing protein 0.0272 0.0627 0.0627
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0132 0.0086 0.0086
Echinococcus granulosus casein kinase i 0.022 0.0427 0.0427
Schistosoma mansoni kinase 0.0586 0.1845 0.1845
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0584 0.183
Giardia lamblia Kinase, AGC AKT 0.0237 0.0493 0.092
Onchocerca volvulus 0.0272 0.0627 0.2237
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0502 0.1519 0.1519
Loa Loa (eye worm) TK protein kinase 0.0258 0.0573 0.0573
Brugia malayi Protein kinase domain containing protein 0.0248 0.0534 0.0534
Brugia malayi Cam kinase protein 1 0.0204 0.0365 0.0365
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0282 0.0666 0.0664
Echinococcus multilocularis C type lectin domian containing protein 0.0502 0.1519 0.1519
Echinococcus granulosus neurogenic locus notch protein 0.0272 0.0627 0.0627
Plasmodium vivax unspecified product 0.0203 0.036 0.0154
Echinococcus granulosus dual specificity protein kinase clk2 0.0312 0.0781 0.0781
Brugia malayi Stress-activated protein kinase jnk-1 0.0537 0.1652 0.1652
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0357 0.0955 0.0955
Schistosoma mansoni vesicular amine transporter 0.052 0.159 0.159
Trichomonas vaginalis CAMK family protein kinase 0.0556 0.1729 0.5424
Onchocerca volvulus 0.0227 0.0454 0.1618
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.0249 0.0249
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0933 0.3187 0.2803
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0276 0.0643 0.0557
Schistosoma mansoni nephrin 0.0306 0.0759 0.0759
Leishmania major trypanothione reductase 0.2692 1 1
Brugia malayi Egg laying defective protein 4 0.0174 0.0249 0.0249
Trypanosoma cruzi cdc2-related kinase 3 0.0241 0.0507 0.0505
Trichomonas vaginalis AGC family protein kinase 0.0229 0.0461 0.1443
Brugia malayi Calcium binding EGF domain containing protein 0.0272 0.0627 0.0627
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0173 0.0242 0.0242
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0241 0.0507 0.0507
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.0759 0.0759
Echinococcus multilocularis c4b binding protein beta chain 0.0502 0.1519 0.1519
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0278 0.0278
Plasmodium falciparum serine/threonine protein kinase, putative 0.024 0.0505 0.0418
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0327 0.0841 0.0841
Entamoeba histolytica protein kinase, putative 0.0579 0.1815 0.7509
Loa Loa (eye worm) hypothetical protein 0.0182 0.0277 0.0277
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0318 0.0805 0.0805
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0248 0.0533 0.0533
Schistosoma mansoni serine/threonine-protein kinase 0.0333 0.0865 0.0865
Entamoeba histolytica protein kinase, putative 0.0168 0.0226 0.0933
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0204 0.0365 0.0159
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0154 0.0169 0.0169
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0477 0.1422 0.1422
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0283 0.0668 0.2093
Loa Loa (eye worm) hypothetical protein 0.0155 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Onchocerca volvulus 0.0272 0.0627 0.2237
Echinococcus multilocularis dual specificity testis specific protein kinase 0.045 0.1316 0.1316
Giardia lamblia Kinase, CK1 Casein kinase 0.022 0.0427 0.0697
Schistosoma mansoni atypical protein kinase C 0.0593 0.1871 0.1871
Giardia lamblia Kinase, CMGC MAPK 0.017 0.0231 0.0035
Echinococcus multilocularis titin 0.0132 0.0084 0.0084
Schistosoma mansoni nephrin related 0.0132 0.0084 0.0084
Schistosoma mansoni cell adhesion molecule 0.0155 0.0175 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0261 0.0584 0.183
Echinococcus multilocularis roundabout 2 0.0826 0.2775 0.2775
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0498 0.1503 0.1503
Leishmania major protein kinase A catalytic subunit isoform 2 0.0229 0.0461 0.0373
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0272 0.0627 0.0627
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0272 0.0627 0.0627
Echinococcus granulosus protein tyrosine kinase 0.0605 0.1918 0.1918
Brugia malayi Immunoglobulin I-set domain containing protein 0.0287 0.0686 0.0686
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0799 0.0799
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0261 0.0584 0.0584
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0666 0.2085
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0155 0.0175 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0158 0.0158
Loa Loa (eye worm) disorganized muscle protein 1 0.0132 0.0084 0.0084
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0132 0.0084 0.0084
Echinococcus granulosus basement membrane specific heparan sulfate 0.0155 0.0175 0.0175
Trypanosoma brucei casein kinase I, isoform 2 0.022 0.0427 0.0339
Plasmodium falciparum thioredoxin reductase 0.0933 0.3187 0.3124
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Schistosoma mansoni glutamate synthase 0.0248 0.0533 0.0533
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0248 0.0533 0.0532
Giardia lamblia Kinase, CMGC CLK 0.0312 0.0781 0.1891
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Loa Loa (eye worm) TK protein kinase 0.0506 0.1534 0.1534
Loa Loa (eye worm) hypothetical protein 0.029 0.0699 0.0699
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1504 0.5399 0.5399
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0933 0.3187 0.3187
Echinococcus granulosus notch 0.0272 0.0627 0.0627
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3186
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.017 0.0231 0.0229
Echinococcus granulosus protein kinase c iota type 0.0581 0.1823 0.1823
Echinococcus multilocularis neural cadherin 0.0272 0.0628 0.0628
Schistosoma mansoni hemicentin 0.0151 0.0158 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Giardia lamblia Aurora kinase 0.024 0.0505 0.0962
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0127 0.0066 0.0066
Plasmodium falciparum cGMP-dependent protein kinase 0.0174 0.0249 0.0159
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0327 0.0841 0.0841
Plasmodium vivax calcium-dependent protein kinase, putative 0.0204 0.0365 0.0159
Echinococcus multilocularis neuroglian 0.0652 0.21 0.21
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0174 0.0249 0.0249
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0084 0.0084
Trypanosoma cruzi trypanothione reductase, putative 0.2692 1 1
Schistosoma mansoni hypothetical protein 0.0132 0.0084 0.0084
Trypanosoma brucei cdc2-related kinase 3 0.0241 0.0507 0.0419
Onchocerca volvulus 0.0594 0.1875 0.6686
Echinococcus granulosus raf serine:threonine protein kinase 0.0152 0.0164 0.0164
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0478 0.1425 0.1425
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0174 0.0249 0.0159
Giardia lamblia Kinase, CMGC GSK 0.0261 0.0584 0.1228
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0229 0.0461 0.0373
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0533 0.0446
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0248 0.0533 0.0533
Echinococcus granulosus protein kinase C gamma type 0.041 0.1163 0.1163
Loa Loa (eye worm) hypothetical protein 0.0222 0.0435 0.0435
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0164 0.0209 0.0119
Schistosoma mansoni notch 0.0272 0.0627 0.0627
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0333 0.0863 0.0863
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.0759 0.0759
Echinococcus granulosus roundabout 2 0.0306 0.0759 0.0759
Echinococcus multilocularis 0.0311 0.0777 0.0777
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0341 0.0341
Schistosoma mansoni tyrosine kinase 0.0316 0.0799 0.0799
Schistosoma mansoni titin 0.0132 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.052 0.159 0.159
Echinococcus multilocularis dual specificity 0.0248 0.0534 0.0534
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0477 0.1422 0.1422
Echinococcus multilocularis cyclin dependent kinase 9 0.0118 0.003 0.003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0533 0.1668
Onchocerca volvulus 0.0502 0.1519 0.5418
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0318 0.0805 0.0805
Brugia malayi EGF-like domain containing protein 0.0272 0.0627 0.0627
Echinococcus multilocularis rho associated protein kinase 0.066 0.2131 0.2131
Trichomonas vaginalis AGC family protein kinase 0.0349 0.0925 0.29
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0229 0.0461 0.046
Echinococcus multilocularis roundabout 2 0.0306 0.0759 0.0759
Trichomonas vaginalis CMGC family protein kinase 0.0182 0.0278 0.0868
Echinococcus multilocularis dual specificity 0.0282 0.0666 0.0666
Brugia malayi hypothetical protein 0.0539 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Toxoplasma gondii thioredoxin reductase 0.2692 1 1
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.011 0.0002 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Echinococcus multilocularis casein kinase I alpha 0.022 0.0427 0.0427
Echinococcus multilocularis Immunoglobulin 0.0155 0.0175 0.0175
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0175 0.0175
Echinococcus multilocularis glutamate synthase 0.0248 0.0533 0.0533
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0175 0.0175
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0165 0.0213 0.0213
Entamoeba histolytica protein kinase domain containing protein 0.024 0.0505 0.2091
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0168 0.0226 0.0136
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0204 0.0365 0.0365
Schistosoma mansoni protein kinase 0.045 0.1316 0.1316
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0933 0.3187 0.3124
Echinococcus granulosus down syndrome cell adhesion 0.0132 0.0084 0.0084
Brugia malayi Calcium binding EGF domain containing protein 0.0272 0.0627 0.0627
Trichomonas vaginalis CAMK family protein kinase 0.0233 0.0477 0.1494
Brugia malayi Doublecortin family protein 0.0306 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0609 0.1934 0.1934
Echinococcus multilocularis thioredoxin glutathione reductase 0.2692 1 1
Trichomonas vaginalis AGC family protein kinase 0.024 0.0505 0.1582
Loa Loa (eye worm) glutathione reductase 0.2692 1 1
Plasmodium vivax casein kinase 1, putative 0.022 0.0427 0.0222
Schistosoma mansoni protein kinase 0.0745 0.2459 0.2459
Onchocerca volvulus 0.0502 0.1519 0.5418
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.0249 0.0249
Brugia malayi basement membrane proteoglycan 0.0155 0.0175 0.0175
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0311 0.0777 0.0777
Echinococcus granulosus protein kinase c epsilon type 0.0415 0.118 0.118
Echinococcus multilocularis PAK box P21 Rho binding 0.013 0.0078 0.0078
Loa Loa (eye worm) TK protein kinase 0.0322 0.0822 0.0822
Trichomonas vaginalis AGC family protein kinase 0.0173 0.0242 0.0756
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.1321 0.1321
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0227 0.0454 0.0452
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0199 0.0345 0.0345
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0155 0.0175 0.0175
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0293 0.0711 0.0711
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0248 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0166 0.0216 0.0216
Echinococcus granulosus expressed protein 0.0168 0.0226 0.0226
Plasmodium vivax glycogen synthase kinase 3, putative 0.0261 0.0584 0.0383
Entamoeba histolytica cyclin C, putative 0.0734 0.2417 1
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.0308 0.0308
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.017 0.0231 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0248 0.0533 0.0532
Schistosoma mansoni protein kinase 0.022 0.0427 0.0427
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0312 0.0781 0.078
Entamoeba histolytica cell division protein kinase 2, putative 0.0241 0.0507 0.2097
Brugia malayi Muscle positioning protein 4 0.0272 0.0627 0.0627
Entamoeba histolytica protein kinase, putative 0.0248 0.0534 0.2209
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0374 0.1023 0.1023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0134 0.0091 0.009
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0175 0.0175
Plasmodium falciparum calcium-dependent protein kinase 4 0.0204 0.0365 0.0277
Brugia malayi Protein kinase domain containing protein 0.1914 0.6989 0.6989
Loa Loa (eye worm) hypothetical protein 0.0151 0.0158 0.0158
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.017 0.0231 0.0231
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0411 0.1167 0.1167
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0716 0.2348 0.2348
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0248 0.0533 0.0533
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0411 0.1167 0.1167
Echinococcus granulosus growth factor receptor bound protein 2 0.0129 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0132 0.0086 0.0086
Entamoeba histolytica protein kinase, putative 0.0261 0.0584 0.2418
Brugia malayi Immunoglobulin I-set domain containing protein 0.0287 0.0686 0.0686
Leishmania major protein kinase A catalytic subunit isoform 1 0.0229 0.0461 0.0373
Toxoplasma gondii rhoptry neck protein RON9 0.0502 0.1519 0.1441
Echinococcus granulosus tyrosine protein kinase Src64B 0.0316 0.0799 0.0799
Trichomonas vaginalis CK1 family protein kinase 0.022 0.0427 0.1335
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0461 0.0461
Trichomonas vaginalis CMGC family protein kinase 0.0182 0.0278 0.0868
Echinococcus multilocularis Immunoglobulin 0.052 0.159 0.159
Echinococcus granulosus leucine rich repeat containing protein 4 0.0132 0.0084 0.0084
Toxoplasma gondii AGC kinase 0.0229 0.0461 0.0373
Echinococcus granulosus mitogen activated protein kinase 3 0.017 0.0231 0.0231
Brugia malayi Protein kinase domain containing protein 0.0231 0.047 0.047
Schistosoma mansoni hypothetical protein 0.0155 0.0175 0.0175
Onchocerca volvulus 0.0272 0.0627 0.2237
Schistosoma mansoni hypothetical protein 0.0272 0.0627 0.0627
Echinococcus granulosus peroxidasin 0.0288 0.0688 0.0688
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0248 0.0533 0.0533
Echinococcus multilocularis casein kinase i 0.022 0.0427 0.0427
Schistosoma mansoni septate junction protein 0.0155 0.0175 0.0175
Echinococcus granulosus dual specificity 0.0282 0.0666 0.0666
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0248 0.0534 0.0447
Schistosoma mansoni serine/threonine protein kinase 0.0438 0.1272 0.1272
Giardia lamblia Kinase, NEK 0.0276 0.0643 0.1426
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0164 0.0209 0.0119
Echinococcus multilocularis calcium activated potassium channel 0.0273 0.0633 0.0633
Loa Loa (eye worm) hypothetical protein 0.0676 0.2191 0.2191
Echinococcus granulosus protein jagged 2 0.0272 0.0627 0.0627
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0261 0.0584 0.0584
Onchocerca volvulus 0.0132 0.0084 0.03
Brugia malayi RhoGAP domain containing protein 0.0154 0.0169 0.0169
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0349 0.0925 0.0925
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0154 0.0169 0.0169
Echinococcus multilocularis hemicentin 1 0.0287 0.0686 0.0686
Echinococcus granulosus serine:threonine protein kinase 0.0231 0.047 0.047
Schistosoma mansoni titin 0.0132 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0282 0.0667 0.0667
Brugia malayi Protein kinase domain containing protein 0.0594 0.1875 0.1875
Brugia malayi intracellular kinase 0.0261 0.0584 0.0584
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0175 0.0175
Trichomonas vaginalis STE family protein kinase 0.0171 0.0238 0.0742
Echinococcus multilocularis serine:threonine protein kinase N2 0.0327 0.0841 0.0841
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0175 0.0175
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0251 0.0548 0.0548
Brugia malayi Protein kinase domain containing protein 0.044 0.128 0.128
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0248 0.0533 0.0446
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0241 0.0507 0.0419
Loa Loa (eye worm) hypothetical protein 0.0391 0.1088 0.1088
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0227 0.0454 0.0452
Brugia malayi Prion-like- 0.0132 0.0084 0.0084
Echinococcus multilocularis hemicentin 1 0.0287 0.0686 0.0686
Echinococcus multilocularis nervana 2 0.0251 0.0548 0.0548
Giardia lamblia Kinase, CMGC CDK 0.0241 0.0507 0.0966
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0241 0.0507 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.1152 0.1152
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0261 0.0584 0.0584
Entamoeba histolytica protein kinase, putative 0.0189 0.0307 0.1269
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0666 0.2085
Brugia malayi SH2 domain containing protein 0.0458 0.135 0.135
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1004 0.3464 0.3464
Trypanosoma brucei protein kinase, putative 0.0261 0.0584 0.0498
Brugia malayi Protein kinase domain 0.0174 0.0249 0.0249
Toxoplasma gondii selenide, water dikinase 0.0248 0.0533 0.0446
Echinococcus multilocularis mitogen activated protein kinase 11 0.0323 0.0824 0.0824
Schistosoma mansoni cell adhesion molecule 0.0695 0.2265 0.2265
Brugia malayi Prion-like- 0.0132 0.0084 0.0084
Brugia malayi serine/threonine-protein kinase plk-2 0.0549 0.1699 0.1699
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Brugia malayi Protein kinase domain containing protein 0.0136 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0151 0.0158 0.0158
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0155 0.0175 0.0175
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0323 0.0824 0.074
Echinococcus granulosus c4b binding protein beta chain 0.0502 0.1519 0.1519
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0132 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0155 0.0175 0.0175
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0745 0.2459 0.2459
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0248 0.0533 0.0446
Loa Loa (eye worm) hypothetical protein 0.0367 0.0996 0.0996
Loa Loa (eye worm) AGC/AKT protein kinase 0.0594 0.1875 0.1875
Leishmania major casein kinase II, putative 0.0203 0.036 0.0271
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2692 1 1
Leishmania major protein kinase, putative 0.0312 0.0781 0.0696
Onchocerca volvulus 0.0502 0.1519 0.5418
Trichomonas vaginalis CK1 family protein kinase 0.022 0.0427 0.1335
Loa Loa (eye worm) AGC/PKN protein kinase 0.0591 0.1862 0.1862
Schistosoma mansoni septate junction protein 0.0155 0.0175 0.0175
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0799 0.0799
Brugia malayi Protein kinase domain containing protein 0.0136 0.0101 0.0101
Entamoeba histolytica protein kinase domain containing protein 0.0248 0.0534 0.2209
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Trypanosoma cruzi casein kinase, putative 0.022 0.0427 0.0425
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0248 0.0533 0.2205
Echinococcus granulosus Vam6:Vps39 protein 0.0227 0.0454 0.0454
Schistosoma mansoni tyrosine kinase 0.0436 0.1264 0.1264
Echinococcus multilocularis transfer RNA-Phe 0.0151 0.0158 0.0158
Onchocerca volvulus 0.0132 0.0084 0.03
Echinococcus multilocularis tyrosine protein kinase Srms 0.0258 0.0573 0.0573
Schistosoma mansoni myosin-binding protein-related 0.0151 0.0158 0.0158
Echinococcus granulosus NDR protein kinase 0.0327 0.0841 0.0841
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Brugia malayi Cadherin domain containing protein 0.0272 0.0628 0.0628
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0167 0.022 0.0011
Giardia lamblia Kinase, AGC PKA 0.0318 0.0805 0.197
Schistosoma mansoni septate junction protein 0.0287 0.0686 0.0686
Echinococcus granulosus Immunoglobulin 0.052 0.159 0.159
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Brugia malayi Protein kinase domain containing protein 0.0349 0.0925 0.0925
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0204 0.0365 0.0365
Echinococcus multilocularis N chimaerin 0.0154 0.0169 0.0169
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0306 0.0759 0.0759
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0306 0.0759 0.0759
Plasmodium vivax serine/threonine kinase-1, putative 0.0312 0.0781 0.0584
Entamoeba histolytica hypothetical protein 0.0404 0.1139 0.4712
Giardia lamblia Thioredoxin reductase 0.0248 0.0533 0.1055
Echinococcus multilocularis casein kinase I alpha 0.022 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0182 0.0277 0.0277
Echinococcus granulosus Immunoglobulin subtype 0.0155 0.0175 0.0175
Echinococcus multilocularis casein kinase I delta 0.022 0.0427 0.0427
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0127 0.0066 0.0066
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0168 0.0226 0.0136
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0688 0.2239 0.2239
Echinococcus granulosus tyrosine kinase 0.0136 0.0101 0.0101
Giardia lamblia Kinase, CMGC CDK 0.0241 0.0507 0.0966
Brugia malayi kettin 0.0132 0.0084 0.0084
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0165 0.0213 0.0213
Schistosoma mansoni nephrin 0.0671 0.2174 0.2174
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0287 0.0686 0.0686
Echinococcus granulosus activin receptor type 0.0134 0.0091 0.0091
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0169 0.0169
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0677 0.2197 0.2197
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0134 0.0091 0.009
Echinococcus multilocularis protein jagged 2 0.0272 0.0627 0.0627
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.017 0.0231 0.0141
Echinococcus multilocularis protein kinase shaggy 0.0261 0.0584 0.0584
Giardia lamblia Kinase, NEK 0.0276 0.0643 0.1426
Trichomonas vaginalis AGC family protein kinase 0.024 0.0505 0.1582
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0168 0.0226 0.0136
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0171 0.0238 0.0984
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0177 0.0261 0.0261
Echinococcus granulosus titin 0.0217 0.0415 0.0415
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0217 0.0415 0.0415
Onchocerca volvulus 0.029 0.0699 0.2491
Echinococcus granulosus protein jagged 1 0.0272 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0472 0.14 0.14
Trichomonas vaginalis apoptosis inducing factor, putative 0.0248 0.0533 0.1668
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Loa Loa (eye worm) TK/EGFR protein kinase 0.0725 0.2382 0.2382
Echinococcus granulosus casein kinase I alpha 0.022 0.0427 0.0427
Plasmodium falciparum glutathione reductase 0.2692 1 1
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Entamoeba histolytica p21-activated kinase 0.019 0.0309 0.1277
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0248 0.0533 0.0446
Brugia malayi Immunoglobulin I-set domain containing protein 0.0287 0.0686 0.0686
Echinococcus granulosus casein kinase I gamma 0.0433 0.125 0.125
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0248 0.0533 0.0533
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.1699 0.5331
Trypanosoma brucei rac serine-threonine kinase, putative 0.0594 0.1875 0.18
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0261 0.0584 0.0498
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0158 0.0158
Brugia malayi Protein kinase domain containing protein 0.0433 0.125 0.125
Onchocerca volvulus 0.0502 0.1519 0.5418
Schistosoma mansoni serine/threonine protein kinase 0.0498 0.1503 0.1503
Echinococcus multilocularis titin 0.0132 0.0084 0.0084
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0233 0.0477 0.0477
Schistosoma mansoni protein kinase 0.0391 0.109 0.109
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0438 0.1272 0.1272
Plasmodium falciparum casein kinase 2, alpha subunit 0.0203 0.036 0.0271
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0282 0.0666 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0282 0.0666 0.0666
Schistosoma mansoni serine/threonine protein kinase 0.0165 0.0213 0.0213
Schistosoma mansoni tyrosine kinase 0.0436 0.1264 0.1264
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0258 0.0573 0.0573
Brugia malayi Protein kinase domain containing protein 0.0125 0.0058 0.0058
Echinococcus multilocularis serine:threonine protein kinase 3 0.0521 0.1594 0.1594
Entamoeba histolytica casein kinase, putative 0.0203 0.036 0.1488
Brugia malayi Sushi domain 0.0502 0.1519 0.1519
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Brugia malayi Cadherin domain containing protein 0.0272 0.0628 0.0628
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0533 0.2205
Echinococcus multilocularis protein tyrosine kinase 0.0605 0.1918 0.1918
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Echinococcus granulosus Immunoglobulin 0.0155 0.0175 0.0175
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0316 0.0799 0.0799
Leishmania major protein kinase, putative 0.0204 0.0365 0.0277
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0533 0.0533
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0312 0.0781 0.0696
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0155 0.0175 0.0175
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0066 0.0066
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0158 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0175 0.0175
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0248 0.0533 0.2205
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0158 0.0158
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0666 0.2085
Trichomonas vaginalis CAMK family protein kinase 0.0204 0.0365 0.1142
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0241 0.0507 0.0507
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0312 0.0781 0.078
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0097 0.04
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0724 0.2377 0.2377
Giardia lamblia Kinase, CDC7 0.0182 0.0278 0.0195
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0533 0.1668
Giardia lamblia Kinase, CMGC SRPK 0.0168 0.0226 0.0019
Brugia malayi protein-tyrosine kinase 0.0258 0.0573 0.0573
Loa Loa (eye worm) hypothetical protein 0.0155 0.0175 0.0175
Schistosoma mansoni tyrosine kinase 0.0194 0.0327 0.0327
Echinococcus multilocularis hypothetical protein 0.0207 0.0376 0.0376
Onchocerca volvulus Tyrosine kinase homolog 0.0834 0.2804 1
Echinococcus granulosus serine:threonine protein kinase 3 0.0521 0.1594 0.1594
Echinococcus multilocularis neurogenic locus protein delta 0.0272 0.0627 0.0627
Echinococcus granulosus NCK adaptor protein 0.0127 0.0066 0.0066
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0229 0.0461 0.0461
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0066 0.0066
Brugia malayi Cyclin, N-terminal domain containing protein 0.0724 0.2377 0.2377
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0306 0.0759 0.0759
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0132 0.0084 0.0084
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0933 0.3187 0.2803
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0745 0.2459 0.2459
Echinococcus multilocularis titin 0.0132 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0171 0.0238 0.0236
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.1699 0.1699
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3186
Onchocerca volvulus Peroxidasin homolog 0.0132 0.0086 0.0307
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3186
Echinococcus granulosus protein jagged 1 0.0272 0.0627 0.0627
Brugia malayi Fes/CIP4 homology domain containing protein 0.0209 0.0382 0.0382
Onchocerca volvulus Putative titin 0.0132 0.0084 0.03
Onchocerca volvulus 0.0502 0.1519 0.5418
Schistosoma mansoni vam6/vps39 related 0.0227 0.0454 0.0454
Echinococcus granulosus CDC7 cell division cycle 7 0.0182 0.0278 0.0278
Entamoeba histolytica PH domain containing protein kinase, putative 0.0333 0.0865 0.3577
Onchocerca volvulus 0.0132 0.0084 0.03
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Leishmania major hypothetical protein, conserved 0.0248 0.0533 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.1699 0.5331
Trichomonas vaginalis CMGC family protein kinase 0.017 0.0231 0.0719
Brugia malayi Leucine Rich Repeat family protein 0.0132 0.0086 0.0086
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0174 0.0249 0.0249
Treponema pallidum NADH oxidase 0.0933 0.3187 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0933 0.3187 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.1862 0.1862
Schistosoma mansoni hypothetical protein 0.0272 0.0627 0.0627
Leishmania major protein kinase A catalytic subunit 0.0229 0.0461 0.0373
Entamoeba histolytica protein kinase, putative 0.024 0.0505 0.2091
Onchocerca volvulus 0.0282 0.0667 0.2378
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Toxoplasma gondii rhoptry neck protein RON1 0.0502 0.1519 0.1441
Onchocerca volvulus 0.022 0.0427 0.1522
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0716 0.2348 0.2348
Toxoplasma gondii AGC kinase 0.0229 0.0461 0.0373
Schistosoma mansoni notch 0.0272 0.0627 0.0627
Brugia malayi Protein kinase domain containing protein 0.0716 0.2348 0.2348
Loa Loa (eye worm) hypothetical protein 0.0229 0.0461 0.0461
Loa Loa (eye worm) hypothetical protein 0.0539 0.1663 0.1663
Schistosoma mansoni cell adhesion molecule 0.0306 0.0759 0.0759
Brugia malayi Immunoglobulin I-set domain containing protein 0.0306 0.0759 0.0759
Schistosoma mansoni tyrosine kinase 0.0504 0.1525 0.1525
Schistosoma mansoni serine/threonine protein kinase 0.0969 0.3327 0.3327
Schistosoma mansoni titin 0.0132 0.0084 0.0084
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0498 0.1503 0.1503
Echinococcus multilocularis myosin iiia 0.0171 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Trypanosoma brucei cdc2-related kinase 1 0.0241 0.0507 0.0419
Plasmodium falciparum protein serine/threonine kinase-1 0.0312 0.0781 0.0696
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Brugia malayi serine/threonine-protein kinase PAK 7 0.0471 0.1399 0.1399
Onchocerca volvulus 0.0502 0.1519 0.5418
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0229 0.0461 0.0373
Schistosoma mansoni hypothetical protein 0.0155 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Echinococcus granulosus tyrosine protein kinase ABL1 0.0136 0.0101 0.0101
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0549 0.1699 0.1699
Echinococcus granulosus cGMP dependent protein kinase 0.0174 0.0249 0.0249
Echinococcus granulosus low density lipoprotein receptor ldl 0.0155 0.0175 0.0175
Leishmania major casein kinase, putative 0.022 0.0427 0.0339
Echinococcus granulosus Protein kinase C brain isozyme 0.0495 0.1492 0.1492
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0507 0.0507
Brugia malayi Casein kinase II, alpha chain 0.0203 0.036 0.036
Echinococcus granulosus c src tyrosine kinase 0.0194 0.0327 0.0327
Toxoplasma gondii aurora kinase 0.024 0.0505 0.0418
Plasmodium vivax protein kinase Crk2 0.0241 0.0507 0.0304
Leishmania major protein kinase, putative 0.0312 0.0781 0.0696
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.017 0.0231 0.0229
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0799 0.0799
Brugia malayi Sex muscle abnormal protein 5 0.0127 0.0066 0.0066
Echinococcus granulosus c-Jun N-terminal kinases 0.0537 0.1652 0.1652
Trichomonas vaginalis STE family protein kinase 0.013 0.0078 0.0239
Trichomonas vaginalis STE family protein kinase 0.0174 0.0249 0.0775
Giardia lamblia Kinase, STE STE20 0.0174 0.0249 0.0096
Echinococcus granulosus calcium activated potassium channel 0.0273 0.0633 0.0633
Echinococcus multilocularis casein kinase I alpha 0.022 0.0427 0.0427
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0248 0.0533 0.2205
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0507 0.1586
Loa Loa (eye worm) LAD-2 short isoform 0.0155 0.0175 0.0175
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0229 0.0461 0.0373
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0248 0.0533 0.0533
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0677 0.2197 0.2197
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0227 0.0454 0.0454
Loa Loa (eye worm) thyroid receptor interactor 0.0209 0.0382 0.0382
Trichomonas vaginalis CMGC family protein kinase 0.017 0.0231 0.0719
Echinococcus multilocularis neurogenic locus notch protein 4 0.0272 0.0627 0.0627
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.0249 0.0249
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0155 0.0175 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0213 0.0663
Echinococcus multilocularis c src tyrosine kinase 0.0194 0.0327 0.0327
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Echinococcus granulosus C type lectin domian containing protein 0.0502 0.1519 0.1519
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0306 0.0759 0.0759
Trypanosoma cruzi casein kinase, putative 0.022 0.0427 0.0425
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0249 0.0249
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0669 0.2165 0.2165
Trypanosoma cruzi casein kinase II, putative 0.0203 0.036 0.0358
Brugia malayi Protein kinase domain containing protein 0.0322 0.0822 0.0822
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0933 0.3187 1
Onchocerca volvulus 0.0248 0.0533 0.19
Schistosoma mansoni notch 0.0272 0.0627 0.0627
Echinococcus multilocularis calcium dependent protein kinase 0.0138 0.0109 0.0109
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.017 0.0231 0.0229
Leishmania major NADH dehydrogenase, putative 0.0248 0.0533 0.0446
Echinococcus granulosus roundabout 2 0.0306 0.0759 0.0759
Schistosoma mansoni tyrosine kinase 0.0363 0.098 0.098
Plasmodium falciparum thioredoxin reductase 0.2692 1 1
Schistosoma mansoni rap gtpase-activating protein 0.0227 0.0454 0.0454
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Brugia malayi Protein kinase domain containing protein 0.0333 0.0863 0.0863
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0533 0.1668
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0451 0.1321 0.1321
Giardia lamblia High cysteine protein 0.0272 0.0627 0.1373
Echinococcus multilocularis protein jagged 1 0.0272 0.0627 0.0627
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Schistosoma mansoni basigin related 0.0155 0.0175 0.0175
Giardia lamblia Kinase, CMGC DYRK 0.0282 0.0666 0.1502
Schistosoma mansoni notch 0.0272 0.0627 0.0627
Schistosoma mansoni serine/threonine protein kinase 0.0433 0.125 0.125
Brugia malayi serine/threonine-protein kinase 6 0.024 0.0505 0.0505
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0442 0.1285 0.1285
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0841 0.0841
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0248 0.0533 0.2205
Echinococcus granulosus casein kinase I alpha 0.022 0.0427 0.0427
Entamoeba histolytica PH domain containing protein kinase, putative 0.0245 0.0521 0.2157
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.022 0.0427 0.0427
Onchocerca volvulus 0.0502 0.1519 0.5418
Brugia malayi STE20-like kinase MST 0.0521 0.1594 0.1594
Schistosoma mansoni roundabout 0.0287 0.0686 0.0686
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0933 0.3187 0.3187
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.0781 0.0781
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.022 0.0427 0.0427
Schistosoma mansoni hypothetical protein 0.0248 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0318 0.0804 0.0804
Entamoeba histolytica hypothetical protein 0.0248 0.0534 0.2209
Trypanosoma cruzi Protein kinase B 0.0333 0.0865 0.0863
Trypanosoma cruzi casein kinase, putative 0.022 0.0427 0.0425
Entamoeba histolytica PH domain containing protein kinase, putative 0.0245 0.0521 0.2157
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0262 0.0587 0.0587
Schistosoma mansoni protein kinase 0.0881 0.2988 0.2988
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0807 0.2701 0.2701
Loa Loa (eye worm) hypothetical protein 0.0287 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0287 0.0686 0.0686
Plasmodium vivax thioredoxin reductase, putative 0.2692 1 1
Schistosoma mansoni protein kinase 0.0174 0.0249 0.0249
Schistosoma mansoni ste20-related kinase 0.0416 0.1187 0.1187
Echinococcus multilocularis casein kinase I delta 0.022 0.0427 0.0427
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0207 0.0376 0.0376
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0724 0.2377 0.2377
Plasmodium falciparum glycogen synthase kinase 3 0.0261 0.0584 0.0498
Brugia malayi basement membrane proteoglycan precursor 0.0155 0.0175 0.0175
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0241 0.0507 0.0419
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0163 0.0204 0.0204
Schistosoma mansoni netrin receptor unc5 0.0155 0.0175 0.0175
Echinococcus granulosus glutamate synthase 0.0248 0.0533 0.0533
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0174 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0374 0.1023 0.1023
Trichomonas vaginalis AGC family protein kinase 0.0335 0.0871 0.2728
Schistosoma mansoni protein kinase C mu 0.0442 0.1285 0.1285
Echinococcus granulosus cyclin dependent kinase 19 0.0988 0.3401 0.3401
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0333 0.0863 0.0863
Loa Loa (eye worm) TK/EPH protein kinase 0.0233 0.0477 0.0477
Schistosoma mansoni cell adhesion molecule 0.0306 0.0759 0.0759
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0256 0.0566 0.1773
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0495 0.1492 0.1492
Schistosoma mansoni cell polarity protein 0.0272 0.0627 0.0627
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0584 0.2418
Loa Loa (eye worm) AGC/NDR protein kinase 0.0327 0.0841 0.0841
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Echinococcus multilocularis neurogenic locus notch protein 0.0272 0.0627 0.0627
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0316 0.0799 0.0799
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0248 0.0533 0.0446
Trypanosoma cruzi aurora B kinase, putative 0.024 0.0505 0.0504
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0159 0.019 0.019
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0151 0.0158 0.0158
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0204 0.0365 0.0159
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0287 0.0686 0.0686
Loa Loa (eye worm) hypothetical protein 0.0391 0.1089 0.1089
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Schistosoma mansoni protein kinase 0.013 0.0078 0.0078
Schistosoma mansoni serine/threonine-protein kinase 0.0333 0.0865 0.0865
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0227 0.0454 0.0454
Trichomonas vaginalis AGC family protein kinase 0.0165 0.0213 0.0663
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0911 0.3103 0.3103
Entamoeba histolytica disulphide oxidoreductase, putative 0.0248 0.0533 0.2205
Schistosoma mansoni hypothetical protein 0.0272 0.0627 0.0627
Trichomonas vaginalis CMGC family protein kinase 0.0282 0.0666 0.2085
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0204 0.0365 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Giardia lamblia NADH oxidase lateral transfer candidate 0.0933 0.3187 1
Entamoeba histolytica protein kinase domain containing protein 0.0261 0.0584 0.2418
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Brugia malayi Protein kinase domain containing protein 0.0622 0.1982 0.1982
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0933 0.3187 0.3187
Entamoeba histolytica protein kinase, putative 0.0248 0.0534 0.2209
Schistosoma mansoni tyrosine kinase 0.0294 0.0714 0.0714
Echinococcus granulosus tyrosine protein kinase Src42A 0.0316 0.0799 0.0799
Entamoeba histolytica protein kinase, putative 0.0174 0.0249 0.1028
Schistosoma mansoni Neurotrimin precursor (hNT) 0.052 0.159 0.159
Loa Loa (eye worm) hypothetical protein 0.0127 0.0066 0.0066
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0327 0.0841 0.0841
Brugia malayi Immunoglobulin I-set domain containing protein 0.0287 0.0686 0.0686
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.011 0.0002 0.0002
Loa Loa (eye worm) AUR protein kinase 0.024 0.0505 0.0505
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0716 0.2348 0.8373
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0498 0.1503 0.1503
Schistosoma mansoni hypothetical protein 0.0272 0.0628 0.0628
Echinococcus multilocularis tyrosine protein kinase shark 0.0363 0.098 0.098
Echinococcus multilocularis tyrosine protein kinase Abl 0.0194 0.0327 0.0327
Echinococcus granulosus dual specificity 0.0282 0.0666 0.0666
Schistosoma mansoni titin 0.0287 0.0686 0.0686
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0203 0.036 0.0154
Trypanosoma cruzi hypothetical protein, conserved 0.0248 0.0533 0.0532
Loa Loa (eye worm) hypothetical protein 0.0287 0.0686 0.0686
Brugia malayi protein kinase C II. 0.0415 0.118 0.118
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0158 0.0158
Schistosoma mansoni tyrosine kinase 0.0316 0.0799 0.0799
Trichomonas vaginalis CAMK family protein kinase 0.0233 0.0477 0.1494
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.019 0.019
Entamoeba histolytica protein kinase, putative 0.0282 0.0666 0.2754
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Schistosoma mansoni cell adhesion molecule 0.0287 0.0686 0.0686
Echinococcus granulosus serine threonine protein kinase nrc 0.0318 0.0805 0.0805
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0451 0.1321 0.1321
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0227 0.0454 0.0454
Loa Loa (eye worm) hypothetical protein 0.029 0.0699 0.0699
Toxoplasma gondii EGF family domain-containing protein 0.0272 0.0627 0.0541
Echinococcus granulosus rho-associated protein kinase 1 0.066 0.2131 0.2131
Echinococcus granulosus dual specificity 0.0282 0.0666 0.0666
Echinococcus granulosus nervana 2 0.0251 0.0548 0.0548
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0372 0.1016 0.1016
Schistosoma mansoni serine/threonine protein kinase 0.066 0.2131 0.2131
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0155 0.0175 0.0175
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0374 0.1023 0.1023
Schistosoma mansoni cell adhesion molecule 0.0132 0.0084 0.0084
Trypanosoma cruzi cdc2-related kinase 1 0.0241 0.0507 0.0505
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Brugia malayi Protein kinase domain containing protein 0.0745 0.2459 0.2459
Loa Loa (eye worm) hypothetical protein 0.0242 0.0511 0.0511
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0633 0.0633
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0933 0.3187 1
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.024 0.0505 0.2091
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0174 0.0249 0.0249
Brugia malayi SRC-1 0.0316 0.0799 0.0799
Loa Loa (eye worm) hypothetical protein 0.0502 0.1519 0.1519
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0159 0.019 0.019
Echinococcus granulosus roundabout 2 0.0826 0.2775 0.2775
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0132 0.0084 0.0084
Onchocerca volvulus 0.0151 0.0158 0.0562
Brugia malayi Delta serrate ligand family protein 0.0272 0.0627 0.0627
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Toxoplasma gondii NADPH-glutathione reductase 0.0933 0.3187 0.3124
Echinococcus granulosus calcium dependent protein kinase 0.0138 0.0109 0.0109
Entamoeba histolytica PH domain containing protein kinase, putative 0.0333 0.0865 0.3577
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0549 0.1699 0.1623
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0881 0.2988 0.2988
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0415 0.0415
Schistosoma mansoni notch 0.0272 0.0627 0.0627
Echinococcus granulosus tyrosine protein kinase shark 0.0363 0.098 0.098
Echinococcus multilocularis death associated protein kinase 1 0.0933 0.3188 0.3188
Echinococcus granulosus ephrin type A receptor 4 A 0.0197 0.0339 0.0339
Schistosoma mansoni growth factor receptor-bound protein 0.0127 0.0066 0.0066
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.024 0.0505 0.2091
Onchocerca volvulus 0.0136 0.0101 0.0358
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Echinococcus granulosus casein kinase ii subunit alpha 0.0203 0.036 0.036
Echinococcus multilocularis Immunoglobulin 0.052 0.159 0.159
Echinococcus granulosus nephrin 0.0151 0.0158 0.0158
Trypanosoma brucei polo-like protein kinase 0.0549 0.1699 0.1623
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Echinococcus granulosus slit 2 protein 0.0318 0.0804 0.0804
Onchocerca volvulus 0.0502 0.1519 0.5418
Loa Loa (eye worm) hypothetical protein 0.0807 0.2701 0.2701
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0633 0.0633
Schistosoma mansoni sulfide quinone reductase 0.0248 0.0533 0.0533
Onchocerca volvulus Serine\/threonine kinase homolog 0.0549 0.1699 0.6061
Echinococcus multilocularis basement membrane specific heparan sulfate 0.052 0.159 0.159
Plasmodium falciparum protein kinase 5 0.0241 0.0507 0.0419
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0155 0.0175 0.0175
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0323 0.0824 0.0824
Echinococcus granulosus titin 0.0132 0.0084 0.0084
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0323 0.0824 0.0823
Schistosoma mansoni growth factor receptor-bound protein 0.0129 0.0075 0.0075
Echinococcus multilocularis 0.0132 0.0084 0.0084
Echinococcus multilocularis Immunoglobulin 0.0155 0.0175 0.0175
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0248 0.0533 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.0841 0.0841
Echinococcus granulosus tyrosine protein kinase Src42A 0.0193 0.0321 0.0321
Echinococcus granulosus titin 0.0132 0.0084 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Echinococcus multilocularis activin receptor type 0.0134 0.0091 0.0091
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Echinococcus granulosus tyrosine protein kinase Blk 0.0258 0.0573 0.0573
Loa Loa (eye worm) projectin 0.0151 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0248 0.0533 0.0533
Brugia malayi Immunoglobulin I-set domain containing protein 0.0506 0.1534 0.1534
Schistosoma mansoni tyrosine kinase 0.0504 0.1525 0.1525
Loa Loa (eye worm) hypothetical protein 0.0287 0.0686 0.0686
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0533 0.0532
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0933 0.3187 0.3186
Entamoeba histolytica protein kinase, putative 0.0594 0.1875 0.7757
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0411 0.1167 0.1167
Schistosoma mansoni hypothetical protein 0.0132 0.0084 0.0084
Brugia malayi Calcium binding EGF domain containing protein 0.0272 0.0627 0.0627
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0227 0.0454 0.0454
Onchocerca volvulus 0.0635 0.2033 0.725
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0579 0.1815 0.1815
Schistosoma mansoni serine/threonine protein kinase 0.0495 0.1492 0.1492
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0316 0.0799 0.0799
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Schistosoma mansoni tyrosine kinase 0.0374 0.1023 0.1023
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0533 0.0533
Echinococcus multilocularis insulin growth factor binding 0.0132 0.0084 0.0084
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Echinococcus granulosus fibropellin Ia 0.0272 0.0627 0.0627
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0933 0.3187 0.3124
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0204 0.0365 0.0159
Brugia malayi Protein kinase domain containing protein 0.0391 0.109 0.109
Onchocerca volvulus Peroxidasin homolog 0.0132 0.0084 0.03
Echinococcus multilocularis aurora kinase A 0.024 0.0505 0.0505
Echinococcus multilocularis expressed conserved protein 0.0174 0.0249 0.0249
Trichomonas vaginalis CMGC family protein kinase 0.0182 0.0278 0.0868
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0533 0.1668
Brugia malayi Myb-like DNA-binding domain containing protein 0.0132 0.0084 0.0084
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0312 0.0781 0.0781
Brugia malayi map kinase activated protein kinase protein 2 0.0801 0.2675 0.2675
Loa Loa (eye worm) hypothetical protein 0.052 0.159 0.159
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0461 0.0461
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0132 0.0084 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0276 0.0643 0.2015
Brugia malayi notch-like transmembrane receptor 0.0272 0.0627 0.0627
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Schistosoma mansoni notch 0.0272 0.0627 0.0627
Loa Loa (eye worm) TK/FAK protein kinase 0.0612 0.1943 0.1943
Echinococcus granulosus titin 0.0217 0.0415 0.0415
Brugia malayi SH2 domain containing protein 0.0136 0.0101 0.0101
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0316 0.0799 0.0799
Plasmodium vivax serine/threonine protein kinase 6, putative 0.024 0.0505 0.0303
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0549 0.1699 0.1699
Schistosoma mansoni serine/threonine protein kinase 0.024 0.0505 0.0505
Leishmania major hypothetical protein, conserved 0.0248 0.0533 0.0446
Loa Loa (eye worm) hypothetical protein 0.0669 0.2165 0.2165
Onchocerca volvulus 0.0391 0.1088 0.388
Loa Loa (eye worm) hypothetical protein 0.0248 0.0536 0.0536
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0472 0.14 0.14
Trypanosoma brucei Casein kinase II 0.0203 0.036 0.0271
Onchocerca volvulus 0.0182 0.0278 0.0991
Entamoeba histolytica cell division protein kinase 2, putative 0.0248 0.0536 0.2219
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.1699 0.5331
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Echinococcus multilocularis expressed protein 0.0168 0.0226 0.0226
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.1167 0.1167
Brugia malayi Protein kinase domain containing protein 0.0168 0.0226 0.0226
Schistosoma mansoni protein kinase 0.0538 0.1657 0.1657
Brugia malayi Immunoglobulin I-set domain containing protein 0.0217 0.0415 0.0415
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0248 0.0533 0.0446
Echinococcus multilocularis serine:threonine protein kinase N2 0.0591 0.1862 0.1862
Echinococcus granulosus aurora kinase A 0.024 0.0505 0.0505
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0203 0.036 0.036
Echinococcus granulosus defective proboscis extension response 0.052 0.159 0.159
Echinococcus multilocularis mitogen activated protein kinase 0.017 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Loa Loa (eye worm) TK/ALK protein kinase 0.0319 0.0808 0.0808
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0132 0.0084 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Schistosoma mansoni ephrin receptor 0.0197 0.0339 0.0339
Echinococcus multilocularis serine threonine protein kinase 0.041 0.1163 0.1163
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0312 0.0781 0.078
Loa Loa (eye worm) thioredoxin reductase 0.2692 1 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0199 0.0345 0.0345
Loa Loa (eye worm) cyclin C 0.1451 0.5195 0.5195
Echinococcus multilocularis casein kinase ii subunit alpha 0.0203 0.036 0.036
Toxoplasma gondii AGC kinase 0.0579 0.1815 0.1739
Echinococcus granulosus dual specificity testis-specific protein kinase 0.045 0.1316 0.1316
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Schistosoma mansoni titin 0.0132 0.0084 0.0084
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0229 0.0461 0.046
Echinococcus granulosus serine:threonine protein kinase 0.0231 0.047 0.047
Echinococcus granulosus cyclin dependent kinase 1 0.0241 0.0507 0.0507
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0507 0.1586
Echinococcus multilocularis mitogen activated protein kinase 11 0.0323 0.0824 0.0824
Trichomonas vaginalis AGC family protein kinase 0.024 0.0505 0.1582
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0248 0.0533 0.0533
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Brugia malayi pregnancy-associated plasma protein-A 0.0502 0.1519 0.1519
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0168 0.0226 0.0224
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0155 0.0175 0.0175
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0248 0.0533 0.0533
Entamoeba histolytica protein kinase, putative 0.0168 0.0226 0.0933
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0306 0.0759 0.0759
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0716 0.2348 0.2348
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0282 0.0666 0.058
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0204 0.0365 0.0365
Brugia malayi Protein kinase domain containing protein 0.0165 0.0213 0.0213
Onchocerca volvulus Neurogenic locus notch homolog 0.0272 0.0627 0.2237
Loa Loa (eye worm) hypothetical protein 0.0255 0.0561 0.0561
Brugia malayi glutamate synthase 0.0248 0.0533 0.0533
Trypanosoma brucei hypothetical protein, conserved 0.0248 0.0533 0.0446
Brugia malayi cell division control protein 2 homolog 0.0241 0.0507 0.0507
Echinococcus granulosus tyrosine protein kinase HCK 0.0189 0.0307 0.0307
Onchocerca volvulus 0.0136 0.0101 0.0358
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0248 0.0533 0.0533
Echinococcus multilocularis neurogenic locus protein delta 0.0272 0.0627 0.0627
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Trypanosoma cruzi casein kinase, putative 0.022 0.0427 0.0425
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0175 0.0175
Schistosoma mansoni titin 0.0217 0.0415 0.0415
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0248 0.0533 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0226 0.0226
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0204 0.0365 0.0365
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0204 0.0365 0.0365
Brugia malayi ephrin receptor 1 precursor 0.0129 0.0072 0.0072
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0229 0.0461 0.0257
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Echinococcus multilocularis serine:threonine protein kinase 0.0231 0.047 0.047
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0933 0.3187 1
Trypanosoma cruzi NADH dehydrogenase, putative 0.0248 0.0533 0.0532
Loa Loa (eye worm) hypothetical protein 0.0204 0.0365 0.0365
Brugia malayi Protein kinase domain containing protein 0.0312 0.0781 0.0781
Echinococcus granulosus serine:threonine protein kinase N2 0.0591 0.1862 0.1862
Trichomonas vaginalis CAMK family protein kinase 0.044 0.128 0.4013
Giardia lamblia Kinase, CMGC GSK 0.0261 0.0584 0.1228
Entamoeba histolytica protein kinase domain containing protein 0.0282 0.0666 0.2754
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1004 0.3464 0.3464
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0262 0.0587 0.0587
Loa Loa (eye worm) hypothetical protein 0.0559 0.1737 0.1737
Loa Loa (eye worm) hypothetical protein 0.0136 0.0101 0.0101
Entamoeba histolytica protein kinase, putative 0.0207 0.0375 0.1553
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0587 0.0587
Schistosoma mansoni serine/threonine protein kinase 0.0716 0.2348 0.2348
Echinococcus granulosus mitogen activated protein kinase 0.017 0.0231 0.0231
Echinococcus multilocularis protein kinase c epsilon type 0.0415 0.118 0.118
Schistosoma mansoni hypothetical protein 0.0227 0.0454 0.0454
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0174 0.0249 0.0249
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0323 0.0824 0.074
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0801 0.2675 0.2675
Schistosoma mansoni glutamate synthase 0.0248 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0287 0.0686 0.0686
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.1699 0.5331
Schistosoma mansoni slit 0.0272 0.0629 0.0629
Trypanosoma brucei NADH dehydrogenase 0.0248 0.0533 0.0446
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0193 0.0321 0.0321
Loa Loa (eye worm) AGC/PKA protein kinase 0.0229 0.0461 0.0461
Giardia lamblia Kinase, NEK 0.0276 0.0643 0.1426
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0471 0.1399 0.1399
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0229 0.0461 0.0461
Echinococcus granulosus serine:threonine protein kinase N2 0.0264 0.0595 0.0595
Brugia malayi p70 ribosomal S6 kinase beta 0.0579 0.1815 0.1815
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0549 0.1699 0.1699
Trichomonas vaginalis STE family protein kinase 0.0174 0.0249 0.0775
Loa Loa (eye worm) hypothetical protein 0.0159 0.019 0.019
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0231 0.0231
Loa Loa (eye worm) Notch2 0.0272 0.0627 0.0627
Schistosoma mansoni tyrosine kinase 0.0725 0.2382 0.2382
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0248 0.0533 0.1668
Entamoeba histolytica casein kinase, putative 0.022 0.0427 0.1766
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0537 0.1652 0.1652
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0154 0.0169 0.0169
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0438 0.1272 0.1272
Schistosoma mansoni hypothetical protein 0.0155 0.0175 0.0175
Echinococcus granulosus dual specificity 0.0248 0.0534 0.0534
Echinococcus granulosus titin 0.0132 0.0084 0.0084
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0533 0.0446
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0458 0.135 0.135
Giardia lamblia Kinase, PLK 0.0549 0.1699 0.4987
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0323 0.0824 0.0823
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0204 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0221 0.0431 0.0431
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Trypanosoma brucei trypanothione reductase 0.2692 1 1
Schistosoma mansoni tyrosine kinase 0.0422 0.1207 0.1207
Schistosoma mansoni serine/threonine protein kinase 0.0415 0.118 0.118
Brugia malayi Immunoglobulin I-set domain containing protein 0.0539 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Schistosoma mansoni septate junction protein 0.0272 0.0627 0.0627
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0151 0.0158 0.0158
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0248 0.0533 0.0533
Brugia malayi Peroxidasin 0.0288 0.0688 0.0688
Onchocerca volvulus 0.066 0.2131 0.7602
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0174 0.0249 0.0249
Echinococcus granulosus tyrosine protein kinase Srms 0.0569 0.1779 0.1779
Echinococcus multilocularis notch 0.0272 0.0627 0.0627
Brugia malayi Tyrosine-protein kinase abl-1 0.0194 0.0327 0.0327
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0229 0.0461 0.046
Echinococcus multilocularis dual specificity protein kinase clk2 0.0312 0.0781 0.0781
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0287 0.0686 0.0686
Schistosoma mansoni hypothetical protein 0.0207 0.0376 0.0376
Brugia malayi Protein kinase domain containing protein 0.0988 0.3401 0.3401
Echinococcus granulosus tyrosine protein kinase otk 0.0287 0.0686 0.0686
Plasmodium vivax serine/threonine protein kinase, putative 0.0168 0.0226 0.0017
Echinococcus granulosus serine:threonine kinase SAD 1 0.0159 0.019 0.019
Entamoeba histolytica protein kinase, putative 0.024 0.0505 0.2091
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Brugia malayi hypothetical protein 0.0227 0.0454 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.019 0.019
Echinococcus granulosus cyclin 0.0724 0.2377 0.2377
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0175 0.0175
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0248 0.0533 0.1668
Echinococcus multilocularis mitogen activated protein kinase 14 0.0323 0.0824 0.0824
Schistosoma mansoni serine/threonine protein kinase 0.0518 0.1579 0.1579
Echinococcus multilocularis tyrosine kinase 0.0136 0.0101 0.0101
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0282 0.0666 0.058
Brugia malayi Protein kinase domain containing protein 0.0319 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0272 0.0628 0.0628
Brugia malayi Immunoglobulin I-set domain containing protein 0.0151 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0938 0.3207 0.3207
Plasmodium falciparum serine/threonine protein kinase KIN 0.0159 0.019 0.01
Trypanosoma cruzi polo-like protein kinase, putative 0.0549 0.1699 0.1698
Schistosoma mansoni serine/threonine protein kinase 0.0438 0.1272 0.1272
Brugia malayi EGF-like domain containing protein 0.0272 0.0627 0.0627
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0287 0.0686 0.2445
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1378 0.491 0.491
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.1422 0.1422
Schistosoma mansoni protein kinase 0.0311 0.0777 0.0777
Onchocerca volvulus Serine\/threonine kinase homolog 0.0333 0.0863 0.3078
Brugia malayi Kinase associated domain 1 family protein 0.0207 0.0376 0.0376
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0933 0.3187 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0676 0.2191 0.2191
Echinococcus granulosus tyrosine kinase 0.0258 0.0573 0.0573
Schistosoma mansoni tyrosine kinase 0.0131 0.0081 0.0081
Plasmodium falciparum NIMA related kinase 1 0.0276 0.0643 0.0557
Brugia malayi Immunoglobulin I-set domain containing protein 0.0177 0.0261 0.0261
Brugia malayi hypothetical protein 0.0155 0.0175 0.0175
Echinococcus granulosus epidermal growth factor receptor 0.0725 0.2382 0.2382
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0251 0.0548 0.0548
Schistosoma mansoni netrin receptor unc5 0.0214 0.0403 0.0403
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Onchocerca volvulus Netrin receptor homolog 0.0191 0.0312 0.1112
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0533 0.0446
Echinococcus multilocularis casein kinase I gamma 0.0433 0.125 0.125
Loa Loa (eye worm) hypothetical protein 0.0282 0.0667 0.0667
Onchocerca volvulus 0.0272 0.0627 0.2237
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0685 0.2228 0.2228
Loa Loa (eye worm) hypothetical protein 0.0521 0.1592 0.1592
Brugia malayi Animal haem peroxidase family protein 0.0132 0.0084 0.0084
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0933 0.3187 0.3124
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0294 0.0712 0.0712
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0716 0.2348 0.2348
Toxoplasma gondii histone kinase SNF1, putative 0.0159 0.019 0.01
Loa Loa (eye worm) CAMK protein kinase 0.0217 0.0415 0.0415
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0933 0.3187 0.3187
Plasmodium falciparum ferrodoxin reductase-like protein 0.0248 0.0533 0.0446
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0438 0.1272 0.1272
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.017 0.0231 0.0141
Schistosoma mansoni peroxidasin 0.0156 0.0177 0.0177
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0327 0.0841 0.0841
Loa Loa (eye worm) AUR protein kinase 0.024 0.0505 0.0505
Brugia malayi Immunoglobulin I-set domain containing protein 0.0132 0.0084 0.0084
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0248 0.0534 0.0532
Toxoplasma gondii CMGC kinase, CK2 family 0.0203 0.036 0.0271
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0204 0.0365 0.0277
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0669 0.2165 0.2165
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0507 0.0507
Echinococcus multilocularis neuroglian 0.0306 0.0759 0.0759
Schistosoma mansoni cell adhesion molecule 0.0151 0.0158 0.0158
Entamoeba histolytica protein kinase, putative 0.0594 0.1875 0.7757
Echinococcus granulosus thioredoxin glutathione reductase 0.2692 1 1
Brugia malayi hypothetical protein 0.0502 0.1519 0.1519
Trichomonas vaginalis CMGC family protein kinase 0.017 0.0231 0.0719
Loa Loa (eye worm) TK protein kinase 0.039 0.1084 0.1084
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0533 0.1668
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Entamoeba histolytica serine/threonine protein kinase, putative 0.0159 0.019 0.0788
Brugia malayi hypothetical protein 0.0451 0.1321 0.1321
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0521 0.1594 0.1594
Echinococcus granulosus netrin receptor unc 5 0.0214 0.0403 0.0403
Brugia malayi casein kinase 1, delta 0.022 0.0427 0.0427
Echinococcus granulosus tyrosine protein kinase Fyn 0.0316 0.0799 0.0799
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.052 0.159 0.159
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0881 0.2988 0.2988
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0451 0.1321 0.1321
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0248 0.0533 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0365 0.0365
Loa Loa (eye worm) hypothetical protein 0.0539 0.1663 0.1663
Schistosoma mansoni hypothetical protein 0.0132 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0539 0.1663 0.1663
Schistosoma mansoni titin 0.0151 0.0158 0.0158
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0159 0.019 0.01
Trichomonas vaginalis CK1 family protein kinase 0.022 0.0427 0.1335
Echinococcus granulosus protein jagged 2 0.0272 0.0627 0.0627
Trichomonas vaginalis STE family protein kinase 0.0174 0.0249 0.0775
Trichomonas vaginalis CAMK family protein kinase 0.0549 0.1699 0.5331
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0863 0.0863
Trichomonas vaginalis glutamate synthase, putative 0.0248 0.0533 0.1668
Entamoeba histolytica casein kinase 1, putative 0.022 0.0427 0.1766
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0248 0.0533 0.0446
Brugia malayi Protein kinase domain containing protein 0.0136 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0207 0.0376 0.0376
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0174 0.0249 0.0249
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.017 0.0231 0.0141
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0261 0.0584 0.0584
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0407 0.1152 0.1152
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0316 0.0799 0.0799
Schistosoma mansoni hypothetical protein 0.0155 0.0175 0.0175
Echinococcus multilocularis cyclin dependent kinase 0.0241 0.0507 0.0507
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0165 0.0213 0.0213
Schistosoma mansoni tyrosine kinase 0.0622 0.1982 0.1982
Brugia malayi Variant SH3 domain containing protein 0.0154 0.0169 0.0169
Brugia malayi Hr1 repeat family protein 0.0591 0.1862 0.1862
Echinococcus multilocularis Immunoglobulin subtype 0.0155 0.0175 0.0175
Echinococcus multilocularis tyrosine protein kinase 0.0322 0.0822 0.0822
Echinococcus granulosus mitogen activated protein kinase 14 0.0323 0.0824 0.0824
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0933 0.3187 0.3124
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.024 0.0505 0.0505
Echinococcus granulosus casein kinase I delta 0.022 0.0427 0.0427
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0293 0.0711 0.0711
Brugia malayi Protein kinase domain containing protein 0.0182 0.0278 0.0278
Loa Loa (eye worm) animal heme peroxidase 0.0132 0.0084 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.1422 0.1422
Plasmodium vivax apical sushi protein, putative 0.0502 0.1519 0.1338
Loa Loa (eye worm) hypothetical protein 0.0132 0.0084 0.0084
Echinococcus multilocularis cyclin dependent kinase 19 0.0988 0.3401 0.3401
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0171 0.0238 0.0984
Plasmodium falciparum serine/threonine protein kinase 0.0168 0.0226 0.0136
Trypanosoma brucei protein kinase, putative 0.0177 0.026 0.0171
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0306 0.0759 0.0759
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0312 0.0781 0.0696
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0333 0.0865 0.0863
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0248 0.0533 0.1668
Loa Loa (eye worm) programmed cell death 8 0.0248 0.0533 0.0533
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0159 0.019 0.0189
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0248 0.0533 0.0532
Trichomonas vaginalis CAMK family protein kinase 0.0159 0.019 0.0593
Echinococcus multilocularis epidermal growth factor receptor 0.0504 0.1525 0.1525
Brugia malayi hypothetical protein 0.0136 0.0101 0.0101
Entamoeba histolytica protein kinase, putative 0.0146 0.0138 0.057
Brugia malayi Thioredoxin reductase 0.2692 1 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0316 0.0799 0.0799
Echinococcus multilocularis serine:threonine protein kinase 38 0.0327 0.0841 0.0841
Echinococcus multilocularis dual specificity 0.0282 0.0666 0.0666
Onchocerca volvulus 0.0132 0.0084 0.03
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0415 0.118 0.118
Brugia malayi C1-like domain containing protein 0.0442 0.1285 0.1285
Brugia malayi EGF-like domain containing protein 0.0318 0.0804 0.0804
Loa Loa (eye worm) gastrulation defective protein 1 0.0922 0.3145 0.3145
Trichomonas vaginalis AGC family protein kinase 0.0594 0.1875 0.5881
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0155 0.0175 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0534 0.0534
Brugia malayi GCC2 and GCC3 family protein 0.0774 0.2573 0.2573
Onchocerca volvulus 0.0272 0.0627 0.2237
Loa Loa (eye worm) hypothetical protein 0.0272 0.0627 0.0627
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Echinococcus granulosus nervana 2 0.0251 0.0548 0.0548
Loa Loa (eye worm) hypothetical protein 0.0227 0.0454 0.0454
Trichomonas vaginalis CMGC family protein kinase 0.0203 0.036 0.1124
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0248 0.0533 0.1668
Plasmodium falciparum glutathione reductase 0.0933 0.3187 0.3124
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0199 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0227 0.0454 0.0454
Echinococcus multilocularis serine:threonine protein kinase 0.0231 0.047 0.047
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0101 0.0101
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0149 0.0153 0.0153
Schistosoma mansoni hypothetical protein 0.0272 0.0627 0.0627
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0227 0.0454 0.0366
Echinococcus granulosus Glutaredoxin protein 5 0.0251 0.0548 0.0548
Brugia malayi Temporarily assigned gene name protein 59 0.0227 0.0454 0.0454
Brugia malayi Immunoglobulin I-set domain containing protein 0.0287 0.0686 0.0686
Schistosoma mansoni hypothetical protein 0.0272 0.0627 0.0627
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0716 0.2348 0.2348
Loa Loa (eye worm) SRC-1 0.0316 0.0799 0.0799
Echinococcus multilocularis slit 2 protein 0.0318 0.0804 0.0804
Trypanosoma brucei SNF1-related protein kinases, putative 0.0159 0.019 0.01
Entamoeba histolytica protein kinase, putative 0.0327 0.0841 0.3479
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0407 0.1152 0.1152
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0316 0.0799 0.0799
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0248 0.0534 0.0534
Echinococcus multilocularis ephrin type A receptor 4 A 0.0197 0.0339 0.0339
Loa Loa (eye worm) CDC7 protein kinase 0.0182 0.0278 0.0278
Loa Loa (eye worm) hypothetical protein 0.0231 0.047 0.047
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0306 0.0759 0.0759
Schistosoma mansoni serine/threonine protein kinase 0.0495 0.1492 0.1492
Loa Loa (eye worm) hypothetical protein 0.0155 0.0175 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0231 0.047 0.147
Loa Loa (eye worm) hypothetical protein 0.013 0.0078 0.0078

Activities

Activity type Activity value Assay description Source Reference
Index (binding) = 66 Selectivity index of Adenosine A2A over A1 in Rat ChEMBL. 15978806
Ki (binding) = 1.9 nM In vitro ability to displace [3H]-SCH-58,261 from A2A adenosine receptor in Rat ChEMBL. 15978806
Ki (binding) = 1.9 nM In vitro ability to displace [3H]-SCH-58,261 from A2A adenosine receptor in Rat ChEMBL. 15978806

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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