Detailed information for compound 313756

Basic information

Technical information
  • TDR Targets ID: 313756
  • Name: (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2 -[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S) -2,4-diamino-4-oxobutanoyl]amino]-3-hydroxybu tanoyl]amino]-4-methylpentanoyl]amino]-5-oxop entanoyl]amino]-4-methylpentanoyl]amino]propa noyl]amino]-4-methylpentanoyl]amino]-3-methyl pentanoyl]amino]-3-hydroxypropanoic acid
  • MW: 972.137 | Formula: C43H77N11O14
  • H donors: 14 H acceptors: 14 LogP: -4.09 Rotable bonds: 40
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)O)CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](CC(=O)N)N)CC(C)C)CCC(=O)N)CC(C)C)C)CC(C)C)C
  • InChi: 1S/C43H77N11O14/c1-11-22(8)33(41(65)52-30(18-55)43(67)68)53-40(64)29(16-21(6)7)49-35(59)23(9)47-38(62)27(14-19(2)3)50-37(61)26(12-13-31(45)57)48-39(63)28(15-20(4)5)51-42(66)34(24(10)56)54-36(60)25(44)17-32(46)58/h19-30,33-34,55-56H,11-18,44H2,1-10H3,(H2,45,57)(H2,46,58)(H,47,62)(H,48,63)(H,49,59)(H,50,61)(H,51,66)(H,52,65)(H,53,64)(H,54,60)(H,67,68)/t22-,23-,24+,25-,26-,27-,28-,29-,30-,33-,34-/m0/s1
  • InChiKey: IMZZHBUVEVILGD-ADXCEISTSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2,4-diamino-4-oxo-butanoyl]amino]-3-hydroxy-butanoyl]amino]-4-methyl-pentanoyl]amino]-5-oxo-pentanoyl]amino]-4-methyl-pentanoyl]amino]propanoyl]amino]-4-methyl-pentanoyl]amino]-3-methyl-pentanoyl]amino]-3-hydroxy-propanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2,4-diamino-1,4-dioxobutyl]amino]-3-hydroxy-1-oxobutyl]amino]-4-methyl-1-oxopentyl]amino]-1,5-dioxopentyl]amino]-4-methyl-1-oxopentyl]amino]-1-oxopropyl]amino]-4-methyl-1-oxopentyl]amino]-3-methyl-1-oxopentyl]amino]-3-hydroxypropanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-azanyl-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2,4-bis(azanyl)-4-oxo-butanoyl]amino]-3-hydroxy-butanoyl]amino]-4-methyl-pentanoyl]amino]-5-oxo-pentanoyl]amino]-4-methyl-pentanoyl]amino]propanoyl]amino]-4-methyl-pentanoyl]amino]-3-methyl-pentanoyl]amino]-3-hydroxy-propanoic acid
  • (2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2,4-diamino-4-keto-butanoyl]amino]-3-hydroxy-butanoyl]amino]-4-methyl-pentanoyl]amino]-5-keto-pentanoyl]amino]-4-methyl-pentanoyl]amino]propanoyl]amino]-4-methyl-pentanoyl]amino]-3-methyl-pentanoyl]amino]-3-hydroxy-propionic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) LAD-2 short isoform 0.0155 0.0142 0.0142
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Schistosoma mansoni serine/threonine protein kinase 0.0521 0.1555 0.1555
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0131 0.0049 0.0049
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0301 0.0708 0.0708
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0939 0.3168 0.315
Plasmodium falciparum ferrodoxin reductase-like protein 0.0249 0.0507 0.0482
Schistosoma mansoni atypical protein kinase C 0.0563 0.1715 0.1715
Brugia malayi SH2 domain containing protein 0.0418 0.1156 0.1156
Echinococcus multilocularis casein kinase I alpha 0.0209 0.035 0.035
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0303 0.0713 0.0713
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0193 0.0292 0.0292
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0217 0.0382 0.0264
Echinococcus granulosus NDR protein kinase 0.031 0.0739 0.0739
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0116 0.0116
Echinococcus granulosus protein tyrosine kinase 0.055 0.1665 0.1665
Plasmodium falciparum serine/threonine protein kinase 0.0159 0.0159 0.0133
Echinococcus multilocularis fat cadherin tumor suppressor 0.0274 0.0602 0.0602
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0162 0.0171 0.0799
Schistosoma mansoni tyrosine kinase 0.0401 0.109 0.109
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0841 0.279 0.279
Echinococcus multilocularis PAK box P21 Rho binding 0.0123 0.0019 0.0019
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0293 0.0677 0.0677
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0249 0.0507 0.0482
Onchocerca volvulus 0.0274 0.0602 0.2265
Echinococcus multilocularis casein kinase I delta 0.0209 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0355 0.0915 0.0915
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0172 0.0209 0.0209
Brugia malayi EGF-like domain containing protein 0.0317 0.0767 0.0767
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0156 0.0147 0.0147
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Schistosoma mansoni serine/threonine protein kinase 0.0416 0.115 0.115
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0225 0.0414 0.2078
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0267 0.0576 0.0551
Loa Loa (eye worm) TK protein kinase 0.0354 0.0912 0.0912
Leishmania major protein kinase A catalytic subunit isoform 1 0.0217 0.0382 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0921 0.3097 0.3097
Entamoeba histolytica protein kinase domain containing protein 0.0192 0.0286 0.1406
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0276 0.0611 0.0611
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0249 0.0507 0.039
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Toxoplasma gondii NADPH-glutathione reductase 0.0939 0.3168 0.315
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Giardia lamblia Kinase, NEK 0.0262 0.0555 0.1422
Loa Loa (eye worm) TK protein kinase 0.0293 0.0676 0.0676
Brugia malayi Serine/threonine-protein kinase Pim-3 0.068 0.2169 0.2169
Onchocerca volvulus Neurogenic locus notch homolog 0.0274 0.0602 0.2265
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0178 0.0233 0.0233
Giardia lamblia Kinase, STE STE20 0.0165 0.0181 0.0195
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0428 0.1197 0.1197
Schistosoma mansoni ste20-related kinase 0.0395 0.1069 0.1069
Onchocerca volvulus 0.0216 0.0379 0.141
Echinococcus multilocularis mitogen activated protein kinase 11 0.0306 0.0726 0.0726
Brugia malayi Leucine Rich Repeat family protein 0.0131 0.0051 0.0051
Brugia malayi Protein kinase domain containing protein 0.0841 0.279 0.279
Echinococcus multilocularis rho associated protein kinase 0.0627 0.1964 0.1964
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0939 0.3168 1
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0247 0.0499 0.0499
Plasmodium falciparum serine/threonine protein kinase, putative 0.0225 0.0414 0.0389
Echinococcus multilocularis neurogenic locus notch protein 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0142 0.0142
Schistosoma mansoni protein kinase 0.0225 0.0414 0.0414
Echinococcus granulosus CDC7 cell division cycle 7 0.0172 0.0209 0.0209
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0131 0.0049 0.0049
Echinococcus multilocularis serine threonine protein kinase 0.0389 0.1045 0.1045
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0939 0.3168 0.315
Schistosoma mansoni tyrosine kinase 0.0401 0.109 0.109
Onchocerca volvulus 0.0131 0.0049 0.0146
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Schistosoma mansoni peroxidasin 0.0155 0.0144 0.0144
Brugia malayi Doublecortin family protein 0.029 0.0664 0.0664
Onchocerca volvulus 0.0131 0.0051 0.0153
Loa Loa (eye worm) protein kinase domain-containing protein 0.0411 0.113 0.113
Loa Loa (eye worm) hypothetical protein 0.078 0.2552 0.2552
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0315 0.0761 0.0761
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0939 0.3168 0.2803
Onchocerca volvulus 0.0126 0.003 0.0073
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0293 0.0677 0.0677
Onchocerca volvulus 0.0126 0.003 0.0073
Echinococcus granulosus tyrosine kinase 0.0126 0.003 0.003
Schistosoma mansoni vav2 0.0159 0.0158 0.0158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0939 0.3168 0.315
Treponema pallidum NADH oxidase 0.0939 0.3168 1
Echinococcus granulosus serine:threonine protein kinase 0.0219 0.0391 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1441 0.1441
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0447 0.127 0.127
Echinococcus granulosus defective proboscis extension response 0.0516 0.1536 0.1536
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0155 0.0142 0.0142
Echinococcus granulosus protein kinase C gamma type 0.0389 0.1045 0.1045
Entamoeba histolytica protein kinase, putative 0.0549 0.1662 0.8651
Trichomonas vaginalis glutamate synthase, putative 0.0249 0.0507 0.1549
Echinococcus multilocularis titin 0.021 0.0356 0.0356
Trichomonas vaginalis CAMK family protein kinase 0.0418 0.1158 0.3615
Loa Loa (eye worm) glutathione reductase 0.2711 1 1
Onchocerca volvulus 0.0126 0.003 0.0073
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0162 0.0171 0.0799
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Echinococcus multilocularis protein kinase c iota type 0.0551 0.167 0.167
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0126 0.003 0.003
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0249 0.0507 0.0507
Schistosoma mansoni protein kinase 0.0708 0.2275 0.2275
Schistosoma mansoni roundabout 0.0285 0.0646 0.0646
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0293 0.0677 0.0677
Brugia malayi cell division control protein 2 homolog 0.0228 0.0426 0.0426
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0193 0.029 0.029
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0249 0.0507 0.039
Echinococcus granulosus nephrin 0.0148 0.0116 0.0116
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0463 0.1331 0.1331
Schistosoma mansoni nephrin 0.0303 0.0713 0.0713
Echinococcus granulosus lachesin 0.0285 0.0646 0.0646
Brugia malayi Egg laying defective protein 4 0.016 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0249 0.0507 0.0507
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0306 0.0726 0.0702
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0228 0.0426 0.0426
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0306 0.0726 0.0702
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi SH2 domain containing protein 0.0126 0.003 0.003
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0267 0.0576 0.0576
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0216 0.0379 0.0379
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0217 0.0382 0.0382
Entamoeba histolytica hypothetical protein 0.0235 0.0451 0.2275
Giardia lamblia Aurora kinase 0.0225 0.0414 0.0959
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Echinococcus multilocularis tyrosine kinase 0.0126 0.003 0.003
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0225 0.0414 0.2078
Entamoeba histolytica cell division protein kinase 2, putative 0.0228 0.0426 0.214
Echinococcus multilocularis mitogen activated protein kinase 14 0.0306 0.0726 0.0726
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0316 0.0764 0.074
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0155 0.0142 0.0142
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0428 0.1197 0.1197
Schistosoma mansoni myosin-binding protein-related 0.0148 0.0116 0.0116
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0149 0.0122 0.0096
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.069 0.2207 0.2207
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2711 1 1
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Brugia malayi Protein kinase domain containing protein 0.0577 0.1769 0.1769
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Onchocerca volvulus Tyrosine kinase homolog 0.0797 0.2619 1
Trypanosoma cruzi cdc2-related kinase 1 0.0228 0.0426 0.04
Leishmania major casein kinase II, putative 0.0192 0.0286 0.0261
Loa Loa (eye worm) AGC/PKN protein kinase 0.056 0.1706 0.1706
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0954 0.3226 0.3226
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0358 0.0358
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0249 0.0507 0.0507
Echinococcus granulosus serine:threonine protein kinase N2 0.056 0.1706 0.1706
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.047 0.1356 0.1356
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0594 0.1836 0.1836
Leishmania major hypothetical protein, conserved 0.0249 0.0507 0.0482
Entamoeba histolytica protein kinase, putative 0.0159 0.0159 0.0738
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Loa Loa (eye worm) animal heme peroxidase 0.0131 0.0049 0.0049
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.031 0.0739 0.0739
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0209 0.035 0.035
Loa Loa (eye worm) programmed cell death 8 0.0249 0.0507 0.0507
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0239 0.0468 0.0468
Brugia malayi Protein kinase domain containing protein 0.0608 0.189 0.189
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Schistosoma mansoni basigin related 0.0155 0.0142 0.0142
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0939 0.3168 0.315
Toxoplasma gondii selenide, water dikinase 0.0249 0.0507 0.0482
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0159 0.0159 0.0133
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0306 0.0726 0.0702
Schistosoma mansoni tyrosine kinase 0.035 0.0893 0.0893
Onchocerca volvulus 0.0148 0.0116 0.0404
Echinococcus multilocularis raf serine:threonine protein kinase 0.0143 0.0098 0.0098
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0713 0.0713
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0387 0.1036 0.1036
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0242 0.0479 0.0479
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0192 0.0286 0.0286
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0228 0.0426 0.04
Schistosoma mansoni protein kinase 0.0165 0.0181 0.0181
Brugia malayi Hr1 repeat family protein 0.056 0.1706 0.1706
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Schistosoma mansoni rap gtpase-activating protein 0.0216 0.0379 0.0379
Trypanosoma cruzi cdc2-related kinase 1 0.0228 0.0426 0.04
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0939 0.3168 0.3084
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.0499 0.2528
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Loa Loa (eye worm) one IG domain family member 0.0131 0.0049 0.0049
Echinococcus granulosus Immunoglobulin subtype 0.0155 0.0142 0.0142
Toxoplasma gondii aurora kinase 0.0225 0.0414 0.0389
Plasmodium falciparum calcium-dependent protein kinase 1 0.0193 0.0292 0.0266
Onchocerca volvulus 0.0126 0.003 0.0073
Brugia malayi GCC2 and GCC3 family protein 0.078 0.2552 0.2552
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0379 0.0354
Entamoeba histolytica PH domain containing protein kinase, putative 0.0232 0.0439 0.221
Schistosoma mansoni nephrin related 0.0155 0.0142 0.0142
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0606 0.1884 0.1884
Loa Loa (eye worm) hypothetical protein 0.0124 0.0023 0.0023
Echinococcus multilocularis tyrosine protein kinase otk 0.0285 0.0646 0.0646
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0131 0.0049 0.0049
Loa Loa (eye worm) AUR protein kinase 0.0225 0.0414 0.0414
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0371 0.0977 0.0977
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Brugia malayi intracellular kinase 0.0247 0.0499 0.0499
Giardia lamblia Kinase, CMGC SRPK 0.0159 0.0159 0.0123
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0303 0.0713 0.0713
Echinococcus multilocularis hemicentin 1 0.0285 0.0646 0.0646
Onchocerca volvulus 0.0627 0.1964 0.749
Entamoeba histolytica protein kinase, putative 0.0159 0.0159 0.0738
Brugia malayi Protein kinase domain containing protein 0.0228 0.0426 0.0426
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Brugia malayi Protein kinase domain containing protein 0.0387 0.1037 0.1037
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0228 0.0426 0.04
Schistosoma mansoni titin 0.0148 0.0116 0.0116
Plasmodium vivax calcium-dependent protein kinase, putative 0.0193 0.0292 0.0172
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0448 0.1275 0.1275
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0428 0.1197 0.1197
Giardia lamblia Kinase, AGC PKA 0.0301 0.0708 0.1923
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0149 0.0122 0.0122
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0249 0.0507 0.0507
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0247 0.0499 0.0499
Onchocerca volvulus 0.0274 0.0602 0.2265
Onchocerca volvulus 0.0268 0.058 0.2183
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0306 0.0726 0.0702
Brugia malayi Tyrosine-protein kinase abl-1 0.018 0.0241 0.0241
Echinococcus multilocularis serine:threonine protein kinase N2 0.031 0.0739 0.0739
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0495 0.1455 0.1455
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Plasmodium falciparum glycogen synthase kinase 3 0.0247 0.0499 0.0474
Echinococcus granulosus protein kinase c epsilon type 0.0393 0.1061 0.1061
Echinococcus multilocularis cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Echinococcus multilocularis 0.0295 0.0682 0.0682
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.02 0.0318 0.0318
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0289 0.0289
Onchocerca volvulus 0.0247 0.0499 0.1871
Echinococcus granulosus Glutaredoxin protein 5 0.0239 0.0468 0.0468
Brugia malayi Variant SH3 domain containing protein 0.0144 0.0101 0.0101
Loa Loa (eye worm) casein kinase 0.0349 0.089 0.089
Schistosoma mansoni tyrosine kinase 0.018 0.0241 0.0241
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.069 0.2207 0.2207
Echinococcus granulosus thioredoxin glutathione reductase 0.2711 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0533 0.1603 0.1603
Toxoplasma gondii casein kinase I 0.0209 0.035 0.0324
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0372 0.0979 0.0979
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0506 0.1496 0.1496
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0147 0.0147
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0193 0.0292 0.0266
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0293 0.0677 0.0677
Giardia lamblia Kinase, CMGC GSK 0.0247 0.0499 0.1239
Loa Loa (eye worm) CAMK/PIM protein kinase 0.068 0.2169 0.2169
Echinococcus multilocularis casein kinase I delta 0.0209 0.035 0.035
Echinococcus multilocularis epidermal growth factor receptor 0.0663 0.2104 0.2104
Giardia lamblia Kinase, CMGC GSK 0.0247 0.0499 0.1239
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0379 0.0354
Entamoeba histolytica protein kinase, putative 0.0137 0.0076 0.0297
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0939 0.3168 0.3168
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0144 0.0101 0.0101
Echinococcus granulosus casein kinase I delta 0.0209 0.035 0.035
Echinococcus granulosus dual specificity 0.0267 0.0576 0.0576
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Plasmodium falciparum calcium-dependent protein kinase 4 0.0193 0.0292 0.0266
Trypanosoma brucei cdc2-related kinase 3 0.0228 0.0426 0.04
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Protein kinase domain containing protein 0.029 0.0664 0.0664
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0428 0.1197 0.1197
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0228 0.0426 0.0426
Echinococcus granulosus neurogenic locus notch protein 0.0274 0.0602 0.0602
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0939 0.3168 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.048 0.1397 0.1397
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Brugia malayi SRC-1 0.0293 0.0677 0.0677
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0155 0.0142 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Onchocerca volvulus 0.0126 0.003 0.0073
Echinococcus multilocularis slit 2 protein 0.0317 0.0767 0.0767
Echinococcus granulosus titin 0.0131 0.0049 0.0049
Loa Loa (eye worm) cyclin domain-containing protein 0.0606 0.1884 0.1884
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Brugia malayi protein kinase C3,putative 0.0303 0.0715 0.0715
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi Protein kinase c protein 2 0.0222 0.0402 0.0402
Echinococcus multilocularis cyclin dependent kinase 0.0228 0.0426 0.0426
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0159 0.0159 0.0133
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus multilocularis nervana 2 0.0239 0.0468 0.0468
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0262 0.0555 0.0438
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0142 0.0142
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0954 0.3226 0.3226
Schistosoma mansoni cell adhesion molecule 0.0148 0.0116 0.0116
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0239 0.0468 0.0468
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Giardia lamblia Kinase, PLK 0.0521 0.1555 0.4705
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0838 0.2775 0.2775
Giardia lamblia Glutamate synthase 0.0249 0.0507 0.1265
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0249 0.0507 0.1265
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.016 0.0164 0.0164
Brugia malayi ephrin receptor 1 precursor 0.0121 0.0011 0.0011
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0387 0.1037 0.1037
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0116 0.0116
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0521 0.1555 0.1555
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0155 0.0143 0.0143
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Echinococcus granulosus Immunoglobulin 0.0516 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0144 0.0144
Entamoeba histolytica casein kinase 1, putative 0.0209 0.035 0.1741
Entamoeba histolytica thioredoxin reductase, putative 0.0249 0.0507 0.2569
Toxoplasma gondii AGC kinase 0.0217 0.0382 0.0357
Leishmania major protein kinase, putative 0.0296 0.0685 0.0661
Echinococcus multilocularis titin 0.0131 0.0049 0.0049
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0285 0.0646 0.0646
Brugia malayi Protein kinase domain containing protein 0.0159 0.0159 0.0159
Echinococcus multilocularis 0.0233 0.0445 0.0445
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0249 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus fibropellin Ia 0.0274 0.0602 0.0602
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus tyrosine protein kinase Blk 0.0239 0.0466 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0545 0.0545
Schistosoma mansoni tyrosine kinase 0.0577 0.1769 0.1769
Toxoplasma gondii EGF family domain-containing protein 0.0274 0.0602 0.0577
Schistosoma mansoni cell adhesion molecule 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.039 0.1051 0.1051
Echinococcus multilocularis protein jagged 2 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus neurogenic locus protein delta 0.0274 0.0602 0.0602
Brugia malayi Protein kinase domain containing protein 0.0708 0.2275 0.2275
Schistosoma mansoni serine/threonine protein kinase 0.031 0.0739 0.0739
Onchocerca volvulus 0.0565 0.1724 0.657
Echinococcus multilocularis neurogenic locus notch protein 0.0274 0.0602 0.0602
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Trypanosoma cruzi polo-like protein kinase, putative 0.0521 0.1555 0.1533
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.016 0.0163 0.0137
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0247 0.0499 0.0499
Brugia malayi hypothetical protein 0.0428 0.1197 0.1197
Echinococcus granulosus insulin receptor 0.0577 0.1769 0.1769
Echinococcus granulosus expressed protein 0.0159 0.0159 0.0159
Brugia malayi RhoGAP domain containing protein 0.0144 0.0101 0.0101
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0217 0.0382 0.0382
Trypanosoma brucei casein kinase I, isoform 2 0.0209 0.035 0.0324
Brugia malayi casein kinase 1, delta 0.0209 0.035 0.035
Giardia lamblia Kinase, AGC AKT 0.0225 0.0413 0.0955
Loa Loa (eye worm) cyclin C 0.1221 0.4256 0.4256
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0155 0.0143 0.0143
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0155 0.0142 0.0142
Plasmodium vivax serine/threonine protein kinase, putative 0.0159 0.0159 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0509 0.151 0.151
Loa Loa (eye worm) hypothetical protein 0.0671 0.2132 0.2132
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0155 0.0142 0.0142
Entamoeba histolytica protein kinase, putative 0.0267 0.0576 0.2932
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0242 0.0479 0.0479
Trypanosoma cruzi aurora B kinase, putative 0.0225 0.0414 0.0389
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0239 0.0469 0.0444
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus serine:threonine protein kinase N2 0.0251 0.0512 0.0512
Echinococcus multilocularis NCK adaptor protein 0.012 0.0007 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.2711 1 1
Toxoplasma gondii CMGC kinase, CK2 family 0.0192 0.0286 0.0261
Brugia malayi Temporarily assigned gene name protein 59 0.0216 0.0379 0.0379
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0249 0.0507 0.0507
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0159 0.0159 0.0133
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0939 0.3168 0.315
Brugia malayi Fes/CIP4 homology domain containing protein 0.0197 0.0307 0.0307
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.039 0.1051 0.1051
Entamoeba histolytica cyclin C, putative 0.0615 0.1918 1
Brugia malayi Prion-like- 0.0131 0.0049 0.0049
Trichomonas vaginalis glutathione reductase, putative 0.0939 0.3168 1
Trypanosoma brucei hypothetical protein, conserved 0.0249 0.0507 0.0482
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0939 0.3168 0.315
Echinococcus granulosus low density lipoprotein receptor ldl 0.0155 0.0142 0.0142
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0247 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus multilocularis roundabout 2 0.0303 0.0713 0.0713
Echinococcus granulosus cyclin dependent kinase 19 0.0841 0.279 0.279
Onchocerca volvulus 0.0148 0.0116 0.0404
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.031 0.0739 0.0739
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0159 0.0159 0.0133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0155 0.0142 0.0142
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0393 0.1061 0.1061
Echinococcus granulosus serine:threonine kinase SAD 1 0.0149 0.0122 0.0122
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0149 0.0122 0.0096
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0116 0.0116
Brugia malayi Protein kinase domain containing protein 0.0371 0.0977 0.0977
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0306 0.0726 0.0726
Echinococcus granulosus dual specificity 0.0267 0.0576 0.0576
Echinococcus multilocularis cyclin dependent kinase 1 0.0228 0.0426 0.0426
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Entamoeba histolytica protein kinase 2, putative 0.0301 0.0708 0.3626
Schistosoma mansoni cell polarity protein 0.0274 0.0602 0.0602
Brugia malayi P38 map kinase family protein 2 0.0306 0.0726 0.0726
Entamoeba histolytica protein kinase, putative 0.031 0.0739 0.3793
Echinococcus multilocularis casein kinase i 0.0209 0.035 0.035
Brugia malayi Protein kinase domain containing protein 0.0608 0.189 0.189
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0939 0.3168 0.3084
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0165 0.0181 0.0181
Schistosoma mansoni sulfide quinone reductase 0.0249 0.0507 0.0507
Leishmania major protein kinase, putative 0.0193 0.0292 0.0266
Echinococcus multilocularis rac serine:threonine kinase 0.0316 0.0764 0.0764
Echinococcus granulosus N chimaerin 0.0144 0.0101 0.0101
Schistosoma mansoni netrin receptor unc5 0.0211 0.0358 0.0358
Brugia malayi Protein kinase domain containing protein 0.0156 0.0147 0.0147
Toxoplasma gondii thioredoxin reductase 0.2711 1 1
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Leishmania major protein kinase A catalytic subunit isoform 2 0.0217 0.0382 0.0357
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Schistosoma mansoni titin 0.021 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0216 0.0379 0.0379
Brugia malayi Protein kinase domain containing protein 0.0118 0.0001 0.0001
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0217 0.0382 0.0357
Brugia malayi Immunoglobulin I-set domain containing protein 0.0172 0.0209 0.0209
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0303 0.0713 0.0713
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0521 0.1555 0.1555
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0164 0.0164
Schistosoma mansoni glutamate synthase 0.0249 0.0507 0.0507
Echinococcus multilocularis peroxidasin 0.0286 0.0648 0.0648
Leishmania major hypothetical protein, conserved 0.0249 0.0507 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0414 0.0414
Loa Loa (eye worm) AGC/PKA protein kinase 0.0217 0.0382 0.0382
Echinococcus multilocularis fibropellin Ia 0.0274 0.0602 0.0602
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.035 0.0893 0.0893
Echinococcus granulosus dual specificity 0.0235 0.0451 0.0451
Onchocerca volvulus Serine\/threonine kinase homolog 0.0521 0.1555 0.5921
Echinococcus granulosus nervana 2 0.0239 0.0468 0.0468
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Echinococcus multilocularis dual specificity 0.0267 0.0576 0.0576
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0939 0.3168 0.315
Brugia malayi p70 ribosomal S6 kinase beta 0.0549 0.1662 0.1662
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0606 0.1884 0.1884
Echinococcus multilocularis tyrosine protein kinase 0.0293 0.0676 0.0676
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0293 0.0677 0.0677
Schistosoma mansoni vesicular amine transporter 0.0516 0.1536 0.1536
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0516 0.1536 0.1536
Echinococcus multilocularis serine:threonine protein kinase N2 0.056 0.1706 0.1706
Schistosoma mansoni serine/threonine kinase 0.031 0.0739 0.0739
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0296 0.0685 0.0661
Echinococcus multilocularis dual specificity 0.0267 0.0576 0.0576
Brugia malayi Protein kinase domain 0.0165 0.0181 0.0181
Brugia malayi serine/threonine protein kinase 6 0.0225 0.0414 0.0414
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0391 0.1179
Loa Loa (eye worm) projectin 0.0148 0.0116 0.0116
Echinococcus granulosus neurogenic locus notch protein 0.0274 0.0602 0.0602
Leishmania major protein kinase, putative 0.0162 0.0171 0.0145
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Loa Loa (eye worm) hypothetical protein 0.0801 0.2636 0.2636
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Schistosoma mansoni protein kinase 0.0125 0.0026 0.0026
Schistosoma mansoni protein kinase 0.0425 0.1186 0.1186
Schistosoma mansoni tyrosine kinase 0.0663 0.2104 0.2104
Echinococcus granulosus Immunoglobulin 0.0155 0.0142 0.0142
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0249 0.0507 0.0507
Echinococcus granulosus mitogen activated protein kinase 3 0.016 0.0164 0.0164
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0279 0.062 0.062
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Plasmodium vivax glutathione reductase, putative 0.2711 1 1
Entamoeba histolytica protein kinase, putative 0.0247 0.0499 0.2528
Plasmodium falciparum glutathione reductase 0.0939 0.3168 0.315
Entamoeba histolytica PH domain containing protein kinase, putative 0.0316 0.0764 0.3923
Echinococcus granulosus cyclin dependent kinase 0.0228 0.0426 0.0426
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0293 0.0677 0.0677
Loa Loa (eye worm) notch protein 0.0274 0.0602 0.0602
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0148 0.0116 0.0116
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0149 0.0122 0.0096
Schistosoma mansoni protein kinase 0.0295 0.0682 0.0682
Brugia malayi kettin 0.0131 0.0049 0.0049
Echinococcus granulosus leucine rich repeat containing protein 4 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus c-Jun N-terminal kinases 0.0509 0.151 0.151
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Echinococcus granulosus casein kinase ii subunit alpha 0.0192 0.0286 0.0286
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0249 0.0507 0.0507
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Echinococcus granulosus casein kinase I delta 0.0209 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Echinococcus multilocularis protein jagged 1 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus granulosus Immunoglobulin 0.0155 0.0142 0.0142
Brugia malayi casein kinase I 0.0209 0.035 0.035
Schistosoma mansoni basigin related 0.0155 0.0142 0.0142
Loa Loa (eye worm) gastrulation defective protein 1 0.0779 0.2551 0.2551
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus granulosus tyrosine protein kinase otk 0.0285 0.0646 0.0646
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0545 0.0545
Entamoeba histolytica serine/threonine protein kinase, putative 0.0521 0.1555 0.809
Echinococcus multilocularis dual specificity 0.0235 0.0451 0.0451
Brugia malayi serine/threonine kinase 12 0.0225 0.0414 0.0414
Brugia malayi notch-like transmembrane receptor 0.0274 0.0602 0.0602
Onchocerca volvulus 0.021 0.0356 0.1323
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0472 0.1367 0.1367
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0159 0.0159
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Plasmodium vivax serine/threonine kinase-1, putative 0.0296 0.0685 0.0571
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Onchocerca volvulus 0.0131 0.0049 0.0146
Schistosoma mansoni cell adhesion molecule 0.0285 0.0646 0.0646
Schistosoma mansoni protein kinase 0.0838 0.2775 0.2775
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0316 0.0763 0.0763
Giardia lamblia Thioredoxin reductase 0.0249 0.0507 0.1265
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0144 0.0101 0.0101
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0209 0.0602
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.068 0.2169 0.2169
Onchocerca volvulus 0.0506 0.1496 0.5694
Brugia malayi Cyclin, N-terminal domain containing protein 0.0606 0.1884 0.1884
Brugia malayi STE20-like kinase MST 0.0495 0.1455 0.1455
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0274 0.0602 0.2265
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Onchocerca volvulus 0.0131 0.0049 0.0146
Echinococcus multilocularis serine:threonine protein kinase 38 0.031 0.0739 0.0739
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0653 0.2063 0.2063
Echinococcus multilocularis N chimaerin 0.0144 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.1292 0.1292
Schistosoma mansoni tyrosine kinase 0.0293 0.0677 0.0677
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Onchocerca volvulus 0.0172 0.0209 0.0759
Trypanosoma brucei trypanothione reductase 0.2711 1 1
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0149 0.0122 0.0122
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.068 0.2169 0.2169
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0453 0.1292 0.1292
Trichomonas vaginalis mercuric reductase, putative 0.0939 0.3168 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0173 0.0214 0.0214
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.1367 0.1367
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Entamoeba histolytica protein kinase, putative 0.0563 0.1718 0.8948
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0516 0.1536 0.1536
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Entamoeba histolytica PH domain containing protein kinase, putative 0.0232 0.0439 0.221
Brugia malayi serine/threonine-protein kinase 6 0.0225 0.0414 0.0414
Echinococcus multilocularis death associated protein kinase 1 0.0847 0.2811 0.2811
Schistosoma mansoni protein kinase 0.0371 0.0977 0.0977
Schistosoma mansoni nephrin related 0.0131 0.0049 0.0049
Onchocerca volvulus 0.0209 0.035 0.1299
Giardia lamblia Kinase, STE STE20 0.0162 0.0171 0.0161
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0426 0.129
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0671 0.2132 0.2132
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0172 0.0209 0.0209
Onchocerca volvulus Serine\/threonine kinase homolog 0.0316 0.0763 0.2884
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0303 0.0713 0.0713
Echinococcus granulosus roundabout 2 0.0303 0.0713 0.0713
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0285 0.0646 0.2435
Echinococcus multilocularis casein kinase I alpha 0.0209 0.035 0.035
Brugia malayi Kinase associated domain 1 family protein 0.0197 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0349 0.0892 0.0892
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0509 0.151 0.151
Onchocerca volvulus 0.0131 0.0049 0.0146
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0164 0.0138
Entamoeba histolytica PH domain containing protein kinase, putative 0.0316 0.0764 0.3923
Echinococcus granulosus rho-associated protein kinase 1 0.0627 0.1964 0.1964
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0249 0.0507 0.0482
Schistosoma mansoni tyrosine kinase 0.0348 0.0887 0.0887
Trypanosoma cruzi cdc2-related kinase 3 0.0228 0.0426 0.04
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0713 0.0713
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.021 0.0356 0.0356
Brugia malayi Muscle positioning protein 4 0.0274 0.0602 0.0602
Brugia malayi Fibronectin type III domain containing protein 0.0533 0.1603 0.1603
Echinococcus granulosus C type lectin domian containing protein 0.0506 0.1496 0.1496
Brugia malayi Protein kinase domain containing protein 0.0555 0.1687 0.1687
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Loa Loa (eye worm) hypothetical protein 0.0193 0.0292 0.0292
Echinococcus multilocularis mitogen activated protein kinase 0.016 0.0164 0.0164
Echinococcus multilocularis cyclin dependent kinase 1 0.0228 0.0426 0.0426
Brugia malayi Cam kinase protein 1 0.0193 0.0292 0.0292
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0499 0.1524
Brugia malayi Casein kinase II, alpha chain 0.0192 0.0286 0.0286
Schistosoma mansoni serine/threonine protein kinase 0.068 0.2169 0.2169
Loa Loa (eye worm) hypothetical protein 0.0249 0.0507 0.0507
Brugia malayi Protein kinase domain containing protein 0.0296 0.0685 0.0685
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Echinococcus granulosus titin 0.0131 0.0049 0.0049
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0249 0.0507 0.0482
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Schistosoma mansoni protein kinase 0.0165 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0268 0.058 0.058
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0225 0.0414 0.0414
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Echinococcus granulosus tyrosine protein kinase Src42A 0.0293 0.0677 0.0677
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0126 0.003 0.003
Schistosoma mansoni protein kinase 0.0511 0.1515 0.1515
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0939 0.3168 0.2803
Plasmodium falciparum cGMP-dependent protein kinase 0.016 0.0163 0.0137
Entamoeba histolytica casein kinase, putative 0.0192 0.0286 0.1406
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0249 0.0507 0.0507
Brugia malayi pregnancy-associated plasma protein-A 0.0506 0.1496 0.1496
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Echinococcus multilocularis c4b binding protein beta chain 0.0506 0.1496 0.1496
Schistosoma mansoni hypothetical protein 0.0197 0.0305 0.0305
Loa Loa (eye worm) Notch2 0.0274 0.0602 0.0602
Echinococcus multilocularis protein kinase shaggy 0.0247 0.0499 0.0499
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Brugia malayi Prion-like- 0.0131 0.0049 0.0049
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0247 0.0499 0.0474
Loa Loa (eye worm) TK/EPH protein kinase 0.022 0.0395 0.0395
Trypanosoma brucei SNF1-related protein kinases, putative 0.0149 0.0122 0.0096
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0418 0.1156 0.1156
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Trichomonas vaginalis CK1 family protein kinase 0.0209 0.035 0.105
Echinococcus multilocularis neural cadherin 0.0274 0.0602 0.0602
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0301 0.0708 0.0683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus multilocularis transfer RNA-Phe 0.0148 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0533 0.1603 0.1603
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Brugia malayi map kinase activated protein kinase protein 2 0.0761 0.2479 0.2479
Trypanosoma brucei protein kinase, putative 0.0247 0.0499 0.0474
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Schistosoma mansoni cell adhesion molecule 0.0131 0.0049 0.0049
Echinococcus multilocularis Immunoglobulin 0.0155 0.0142 0.0142
Brugia malayi hypothetical protein 0.0155 0.0142 0.0142
Echinococcus multilocularis neurogenic locus notch protein 4 0.0274 0.0602 0.0602
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0296 0.0685 0.0661
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus netrin receptor unc 5 0.0211 0.0358 0.0358
Schistosoma mansoni slit 0.0274 0.0604 0.0604
Plasmodium falciparum NIMA related kinase 1 0.0262 0.0555 0.053
Entamoeba histolytica protein kinase, putative 0.0125 0.0029 0.0052
Brugia malayi Protein kinase domain containing protein 0.0373 0.0984 0.0984
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0295 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.0801 0.2636 0.2636
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0249 0.0507 0.2569
Echinococcus granulosus tyrosine protein kinase shark 0.0331 0.0823 0.0823
Schistosoma mansoni cell adhesion molecule 0.0148 0.0116 0.0116
Echinococcus multilocularis glutamate synthase 0.0249 0.0507 0.0507
Loa Loa (eye worm) TK protein kinase 0.0239 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0357 0.0923 0.0923
Entamoeba histolytica protein kinase, putative 0.0156 0.0147 0.0674
Schistosoma mansoni serine/threonine protein kinase 0.0841 0.279 0.279
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Loa Loa (eye worm) hypothetical protein 0.0276 0.0611 0.0611
Brugia malayi Delta serrate ligand family protein 0.0274 0.0602 0.0602
Schistosoma mansoni slit 0.0131 0.0051 0.0051
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0379 0.0354
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0453 0.1292 0.1292
Brugia malayi Protein kinase domain containing protein 0.0418 0.1158 0.1158
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0379 0.0379
Brugia malayi Protein kinase domain containing protein 0.0293 0.0676 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0576 0.0576
Entamoeba histolytica protein kinase, putative 0.0225 0.0414 0.2078
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Schistosoma mansoni serine/threonine kinase 0.0418 0.1158 0.1158
Onchocerca volvulus 0.0146 0.011 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0685 0.0685
Echinococcus granulosus mitogen activated protein kinase 0.016 0.0164 0.0164
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0521 0.1555 0.1533
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.1292 0.1292
Echinococcus multilocularis CDC7 cell division cycle 7 0.0172 0.0209 0.0209
Echinococcus granulosus protein kinase shaggy 0.0247 0.0499 0.0499
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Echinococcus granulosus protein jagged 1 0.0274 0.0602 0.0602
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0221 0.0398 0.0398
Schistosoma mansoni cell adhesion molecule 0.0155 0.0142 0.0142
Echinococcus multilocularis cyclin dependent kinase 5 0.0228 0.0426 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0426 0.0426
Echinococcus granulosus serine:threonine protein kinase 3 0.0495 0.1455 0.1455
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0249 0.0507 0.0482
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0249 0.0507 0.2569
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Echinococcus granulosus nervana 2 0.0239 0.0468 0.0468
Echinococcus granulosus mitogen activated protein kinase 14 0.0306 0.0726 0.0726
Entamoeba histolytica p21-activated kinase 0.0179 0.0237 0.1149
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus granulosus contactin 0.0303 0.0713 0.0713
Plasmodium falciparum calcium-dependent protein kinase 5 0.0193 0.0292 0.0266
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Brugia malayi Prion-like- 0.0131 0.0049 0.0049
Brugia malayi serine/threonine-protein kinase plk-2 0.0521 0.1555 0.1555
Brugia malayi Heparan sulfate 0.0155 0.0142 0.0142
Schistosoma mansoni tyrosine kinase 0.0463 0.1331 0.1331
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0209 0.0209
Plasmodium vivax ferrodoxin reductase, putative 0.0249 0.0507 0.039
Echinococcus granulosus neurogenic locus notch protein 4 0.0274 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0239 0.0466 0.0466
Echinococcus multilocularis aurora kinase A 0.0225 0.0414 0.0414
Brugia malayi Temporarily assigned gene name protein 59 0.0249 0.0507 0.0507
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0301 0.0708 0.0593
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0155 0.0142 0.0142
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1402 0.4951 0.4951
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0231 0.0231
Loa Loa (eye worm) TK/INSR protein kinase 0.0577 0.1769 0.1769
Brugia malayi Immunoglobulin I-set domain containing protein 0.0173 0.0214 0.0214
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0228 0.0426 0.0426
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0147 0.0406
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0249 0.0507 0.0507
Echinococcus granulosus basement membrane specific heparan sulfate 0.0155 0.0142 0.0142
Echinococcus granulosus calcium dependent protein kinase 0.0131 0.0052 0.0052
Schistosoma mansoni netrin receptor unc5 0.0155 0.0142 0.0142
Echinococcus granulosus protein jagged 2 0.0274 0.0602 0.0602
Echinococcus multilocularis calcium activated potassium channel 0.0259 0.0545 0.0545
Echinococcus multilocularis dual specificity protein kinase clk2 0.0296 0.0685 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.031 0.0739 0.0739
Schistosoma mansoni tyrosine kinase 0.018 0.0241 0.0241
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.031 0.0739 0.0739
Leishmania major trypanothione reductase 0.2711 1 1
Entamoeba histolytica protein kinase, putative 0.0225 0.0414 0.2078
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0303 0.0713 0.0713
Echinococcus granulosus tyrosine protein kinase Lyn 0.0356 0.0917 0.0917
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0235 0.0451 0.0426
Schistosoma mansoni serine/threonine-protein kinase 0.0316 0.0764 0.0764
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0451 0.0451
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0365 0.0953 0.0953
Brugia malayi hypothetical protein 0.0533 0.1603 0.1603
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0217 0.0382 0.0357
Loa Loa (eye worm) hypothetical protein 0.0516 0.1536 0.1536
Trypanosoma cruzi polo-like protein kinase, putative 0.0521 0.1555 0.1533
Echinococcus granulosus titin 0.021 0.0356 0.0356
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0249 0.0507 0.0482
Onchocerca volvulus 0.0506 0.1496 0.5694
Schistosoma mansoni tyrosine kinase 0.0401 0.109 0.109
Echinococcus multilocularis cyclin dependent kinase 19 0.0841 0.279 0.279
Echinococcus multilocularis insulin growth factor binding 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0303 0.0713 0.0713
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0249 0.0507 0.2569
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus granulosus epidermal growth factor receptor 0.0463 0.1331 0.1331
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0165 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.031 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0563 0.1715 0.1715
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0838 0.2775 0.2775
Plasmodium falciparum protein kinase 5 0.0228 0.0426 0.04
Loa Loa (eye worm) CDC7 protein kinase 0.0172 0.0209 0.0209
Brugia malayi Furin-like cysteine rich region family protein 0.0663 0.2104 0.2104
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Onchocerca volvulus Netrin receptor homolog 0.0187 0.0265 0.0973
Loa Loa (eye worm) hypothetical protein 0.0892 0.2986 0.2986
Brugia malayi protein unc-22 0.021 0.0356 0.0356
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Schistosoma mansoni titin 0.0285 0.0646 0.0646
Schistosoma mansoni cell adhesion molecule 0.0688 0.22 0.22
Echinococcus multilocularis tyrosine protein kinase Blk 0.0239 0.0466 0.0466
Trichomonas vaginalis AGC family protein kinase 0.0329 0.0815 0.2528
Echinococcus granulosus peroxidasin 0.0286 0.0648 0.0648
Plasmodium vivax glycogen synthase kinase 3, putative 0.0247 0.0499 0.0382
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0193 0.0292 0.0172
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0249 0.0507 0.0507
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0708 0.2275 0.2275
Echinococcus granulosus down syndrome cell adhesion 0.0131 0.0049 0.0049
Giardia lamblia Kinase, CK1 Casein kinase 0.0209 0.035 0.0749
Loa Loa (eye worm) hypothetical protein 0.0158 0.0153 0.0153
Echinococcus granulosus tyrosine kinase 0.0239 0.0466 0.0466
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0247 0.0499 0.0499
Onchocerca volvulus Slit protein homolog 0.0317 0.0767 0.2897
Leishmania major protein kinase, putative 0.0296 0.0685 0.0661
Brugia malayi Stress-activated protein kinase jnk-1 0.0509 0.151 0.151
Onchocerca volvulus 0.0131 0.0049 0.0146
Loa Loa (eye worm) hypothetical protein 0.0197 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.023 0.0433 0.0433
Echinococcus granulosus casein kinase I alpha 0.0209 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0216 0.0379 0.0379
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0193 0.0292 0.0292
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0293 0.0677 0.0677
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0231 0.0435 0.0435
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0249 0.0507 0.0507
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0235 0.0451 0.0426
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Brugia malayi serine/threonine-protein kinase PAK 7 0.0447 0.127 0.127
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0156 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Echinococcus multilocularis activin receptor type 0.0125 0.0026 0.0026
Loa Loa (eye worm) CAMK/PIM protein kinase 0.068 0.2169 0.2169
Brugia malayi protein kinase C II. 0.0393 0.1061 0.1061
Entamoeba histolytica protein kinase, putative 0.0176 0.0223 0.1071
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0249 0.0507 0.0507
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0761 0.2479 0.2479
Schistosoma mansoni septate junction protein 0.0274 0.0602 0.0602
Schistosoma mansoni protein kinase 0.0192 0.0286 0.0286
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.016 0.0164 0.0138
Onchocerca volvulus 0.0131 0.0049 0.0146
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0217 0.0382 0.0357
Entamoeba histolytica protein kinase, putative 0.0235 0.0451 0.2275
Loa Loa (eye worm) hypothetical protein 0.0208 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0418 0.1158 0.1158
Echinococcus granulosus casein kinase I gamma 0.0411 0.113 0.113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0142 0.0142
Plasmodium falciparum calcium-dependent protein kinase 3 0.0193 0.0292 0.0266
Schistosoma mansoni vam6/vps39 related 0.0216 0.0379 0.0379
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Trypanosoma cruzi NADH dehydrogenase, putative 0.0249 0.0507 0.0482
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0267 0.0576 0.0551
Brugia malayi Protein kinase domain containing protein 0.0219 0.0391 0.0391
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0219 0.0391 0.0391
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0301 0.0708 0.0683
Echinococcus multilocularis neurogenic locus protein delta 0.0274 0.0602 0.0602
Echinococcus granulosus raf serine:threonine protein kinase 0.0143 0.0098 0.0098
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0141 0.009 0.009
Echinococcus granulosus hypothetical protein 0.0233 0.0445 0.0445
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0235 0.0451 0.0451
Schistosoma mansoni serine/threonine protein kinase 0.047 0.1356 0.1356
Entamoeba histolytica protein kinase domain containing protein 0.0225 0.0414 0.2078
Echinococcus multilocularis fibroblast growth factor receptor 4 0.035 0.0893 0.0893
Giardia lamblia Kinase, CMGC MAPK 0.016 0.0164 0.0139
Echinococcus multilocularis epidermal growth factor receptor 0.0463 0.1331 0.1331
Giardia lamblia Kinase, CDC7 0.0172 0.0209 0.0286
Schistosoma mansoni protein kinase 0.0425 0.1186 0.1186
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0279 0.062 0.062
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Leishmania major hypothetical protein, conserved 0.0249 0.0507 0.0482
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.016 0.0164 0.0138
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.027 0.0588 0.0588
Loa Loa (eye worm) camk/dcamkl protein kinase 0.029 0.0664 0.0664
Echinococcus multilocularis expressed protein 0.0159 0.0159 0.0159
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Brugia malayi Cadherin domain containing protein 0.0274 0.0602 0.0602
Entamoeba histolytica protein kinase, putative 0.0196 0.0301 0.1484
Loa Loa (eye worm) hypothetical protein 0.0148 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0516 0.1536 0.1536
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0149 0.0122 0.0096
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0425 0.1186 0.1186
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Onchocerca volvulus 0.0274 0.0602 0.2265
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0338 0.0851 0.0851
Entamoeba histolytica protein kinase, putative 0.0137 0.0076 0.0297
Mycobacterium tuberculosis Probable oxidoreductase 0.0939 0.3168 0.2803
Echinococcus granulosus cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0516 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0228 0.0426 0.0426
Echinococcus granulosus cyclin 0.0606 0.1884 0.1884
Loa Loa (eye worm) hypothetical protein 0.0533 0.1603 0.1603
Brugia malayi Protein kinase domain containing protein 0.0411 0.113 0.113
Schistosoma mansoni protein kinase 0.0209 0.035 0.035
Echinococcus granulosus glutamate synthase 0.0249 0.0507 0.0507
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0939 0.3168 0.315
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.0398 0.1202
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Schistosoma mansoni serine/threonine-protein kinase 0.0316 0.0764 0.0764
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Loa Loa (eye worm) hypothetical protein 0.0608 0.189 0.189
Echinococcus multilocularis serine:threonine protein kinase 0.0219 0.0391 0.0391
Schistosoma mansoni protein kinase 0.0838 0.2775 0.2775
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Protein kinase domain containing protein 0.0563 0.1718 0.1718
Schistosoma mansoni cell adhesion molecule 0.0303 0.0713 0.0713
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.016 0.0164 0.0138
Giardia lamblia High cysteine protein 0.0274 0.0602 0.1576
Loa Loa (eye worm) hypothetical protein 0.0517 0.1538 0.1538
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0939 0.3168 0.315
Echinococcus granulosus fibroblast growth factor receptor 4 0.035 0.0893 0.0893
Entamoeba histolytica protein kinase domain containing protein 0.0235 0.0451 0.2275
Brugia malayi Immunoglobulin I-set domain containing protein 0.1337 0.4702 0.4702
Onchocerca volvulus Putative cubilin 0.0274 0.0602 0.2265
Giardia lamblia NADH oxidase lateral transfer candidate 0.0939 0.3168 1
Echinococcus granulosus neuroglian 0.0647 0.2039 0.2039
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0939 0.3168 0.315
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0608 0.189 0.189
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0382 0.0382
Leishmania major NADH dehydrogenase, putative 0.0249 0.0507 0.0482
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0316 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0249 0.0507 0.1549
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0156 0.0147 0.0147
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0509 0.151 0.151
Schistosoma mansoni basigin related 0.0155 0.0142 0.0142
Trypanosoma cruzi cdc2-related kinase 3 0.0228 0.0426 0.04
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0549 0.1662 0.1662
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.0398 0.1202
Echinococcus multilocularis neurogenic locus protein delta 0.0274 0.0602 0.0602
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0278 0.0619 0.0619
Schistosoma mansoni glutamate synthase 0.0249 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Brugia malayi Protein kinase domain containing protein 0.182 0.6564 0.6564
Schistosoma mansoni ephrin receptor 0.0186 0.0264 0.0264
Leishmania major protein kinase, putative 0.0225 0.0414 0.0389
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.068 0.2169 0.8274
Plasmodium vivax unspecified product 0.0192 0.0286 0.0166
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Echinococcus granulosus delta-like protein 1 0.0274 0.0602 0.0602
Echinococcus granulosus calcium activated potassium channel 0.0259 0.0545 0.0545
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus multilocularis C type lectin domian containing protein 0.0506 0.1496 0.1496
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Brugia malayi Homeodomain interacting protein kinase protein 1 0.039 0.1051 0.1051
Plasmodium vivax protein kinase Crk2 0.0228 0.0426 0.0308
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0939 0.3168 1
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0274 0.0602 0.0602
Brugia malayi Protein kinase domain containing protein 0.0235 0.0451 0.0451
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0296 0.0685 0.0661
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0131 0.0049 0.0049
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0249 0.0507 0.0482
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Giardia lamblia Kinase, CMGC CDK 0.0228 0.0426 0.0997
Brugia malayi putative serine/threonine kinase SADA gamma 0.0149 0.0122 0.0122
Trypanosoma brucei Casein kinase II 0.0192 0.0286 0.0261
Giardia lamblia Kinase, AGC PKA 0.0217 0.0382 0.0856
Echinococcus granulosus neuroglian 0.0303 0.0713 0.0713
Entamoeba histolytica protein kinase domain containing protein 0.0267 0.0576 0.2932
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0426 0.129
Plasmodium vivax apical sushi protein, putative 0.0506 0.1496 0.1391
Echinococcus granulosus dual specificity protein kinase clk2 0.0296 0.0685 0.0685
Echinococcus granulosus titin 0.0131 0.0049 0.0049
Trichomonas vaginalis CK1 family protein kinase 0.0209 0.035 0.105
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0209 0.0602
Plasmodium vivax tyrosine kinase-like protein, putative 0.0155 0.0144 0.0022
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Trichomonas vaginalis CK1 family protein kinase 0.0209 0.035 0.105
Echinococcus granulosus c src tyrosine kinase 0.018 0.0241 0.0241
Schistosoma mansoni tyrosine kinase 0.055 0.1665 0.1665
Echinococcus multilocularis c src tyrosine kinase 0.018 0.0241 0.0241
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0292 0.0865
Trichomonas vaginalis glutamate synthase, putative 0.0249 0.0507 0.1549
Echinococcus multilocularis down syndrome cell adhesion 0.0131 0.0049 0.0049
Echinococcus granulosus Vam6:Vps39 protein 0.0216 0.0379 0.0379
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0274 0.0602 0.0602
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0301 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Echinococcus multilocularis protein tyrosine kinase 0.055 0.1665 0.1665
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0939 0.3168 1
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0131 0.0051 0.0051
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0262 0.0555 0.053
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0193 0.0292 0.0266
Echinococcus granulosus roundabout 2 0.0819 0.2703 0.2703
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Loa Loa (eye worm) hypothetical protein 0.0149 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0317 0.0767 0.0767
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Echinococcus multilocularis tyrosine protein kinase Srms 0.0239 0.0466 0.0466
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0249 0.0507 0.0482
Onchocerca volvulus 0.0276 0.0611 0.2299
Echinococcus multilocularis insulin receptor 0.0577 0.1769 0.1769
Schistosoma mansoni septate junction protein 0.0285 0.0646 0.0646
Schistosoma mansoni tyrosine kinase 0.0331 0.0823 0.0823
Loa Loa (eye worm) TK/FER protein kinase 0.0418 0.1156 0.1156
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0126 0.003 0.0058
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi basement membrane proteoglycan 0.0155 0.0142 0.0142
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1337 0.4702 0.4702
Brugia malayi phosphoinositide-dependent protein kinase I 0.0156 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0219 0.0391 0.0391
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Trypanosoma cruzi casein kinase II, putative 0.0192 0.0286 0.0261
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Toxoplasma gondii histone kinase SNF1, putative 0.0149 0.0122 0.0096
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0217 0.0382 0.0357
Loa Loa (eye worm) hypothetical protein 0.0448 0.1275 0.1275
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0939 0.3168 0.2803
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0249 0.0507 0.1549
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0242 0.0479 0.0479
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0594 0.1836 0.1836
Plasmodium falciparum serine/threonine protein kinase KIN 0.0149 0.0122 0.0096
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0267 0.0576 0.0551
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0216 0.0379 0.0379
Echinococcus multilocularis serine:threonine protein kinase 0.0219 0.0391 0.0391
Entamoeba histolytica protein kinase domain containing protein 0.039 0.1051 0.5433
Loa Loa (eye worm) AGC/PKA protein kinase 0.0217 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0233 0.0445 0.0445
Echinococcus multilocularis mitogen activated protein kinase 3 0.016 0.0164 0.0164
Onchocerca volvulus 0.0357 0.0923 0.3495
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0249 0.0507 0.0482
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0644 0.2029 0.2029
Echinococcus multilocularis notch 0.0274 0.0602 0.0602
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0148 0.0116 0.0116
Echinococcus multilocularis 0.0184 0.0254 0.0254
Brugia malayi probable protein kinase 0.0511 0.1515 0.1515
Brugia malayi Protein kinase domain containing protein 0.0316 0.0763 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.1037 0.1037
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0209 0.035 0.035
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Echinococcus granulosus mitogen activated protein kinase 11 0.0306 0.0726 0.0726
Echinococcus multilocularis Glutaredoxin protein 5 0.0239 0.0468 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0249 0.0507 0.0482
Echinococcus multilocularis Immunoglobulin 0.0155 0.0142 0.0142
Echinococcus multilocularis expressed conserved protein 0.016 0.0163 0.0163
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0866 0.2885 0.2885
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0217 0.0382 0.0357
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0192 0.0286 0.0166
Toxoplasma gondii AGC kinase 0.0549 0.1662 0.164
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0217 0.0382 0.0357
Entamoeba histolytica casein kinase, putative 0.0209 0.035 0.1741
Plasmodium falciparum casein kinase 1 0.0209 0.035 0.0324
Echinococcus multilocularis Immunoglobulin 0.0516 0.1536 0.1536
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.113 0.113
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0221 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0355 0.0915 0.0915
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0293 0.0677 0.0677
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0296 0.0685 0.0661
Echinococcus granulosus ephrin type A receptor 4 A 0.0186 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0216 0.0379 0.0379
Echinococcus granulosus c4b binding protein beta chain 0.0506 0.1496 0.1496
Loa Loa (eye worm) hypothetical protein 0.0286 0.0648 0.0648
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0249 0.0507 0.0507
Onchocerca volvulus 0.0506 0.1496 0.5694
Trichomonas vaginalis CAMK family protein kinase 0.0243 0.0482 0.147
Schistosoma mansoni tyrosine kinase 0.0268 0.0579 0.0579
Echinococcus granulosus titin 0.021 0.0356 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0479 0.0479
Brugia malayi Immunoglobulin I-set domain containing protein 0.0533 0.1603 0.1603
Entamoeba histolytica disulphide oxidoreductase, putative 0.0249 0.0507 0.2569
Schistosoma mansoni sulfide quinone reductase 0.0249 0.0507 0.0507
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0155 0.0144 0.0118
Loa Loa (eye worm) hypothetical protein 0.0268 0.058 0.058
Trypanosoma cruzi hypothetical protein, conserved 0.0249 0.0507 0.0482
Schistosoma mansoni glutamate synthase 0.0249 0.0507 0.0507
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0159 0.0159 0.0159
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0761 0.2479 0.2479
Schistosoma mansoni hypothetical protein 0.0197 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0173 0.0211 0.0211
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0437 0.1231 0.1231
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0303 0.0713 0.0713
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Echinococcus granulosus insulin growth factor binding 0.0131 0.0049 0.0049
Brugia malayi Cyclin C 0.1221 0.4256 0.4256
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0098 0.0098
Trichomonas vaginalis apoptosis inducing factor, putative 0.0249 0.0507 0.1549
Schistosoma mansoni hemicentin 0.0148 0.0116 0.0116
Schistosoma mansoni protein kinase 0.0838 0.2775 0.2775
Loa Loa (eye worm) SRC-1 0.0293 0.0677 0.0677
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0708 0.2275 0.2275
Schistosoma mansoni growth factor receptor-bound protein 0.012 0.0007 0.0007
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus multilocularis Immunoglobulin 0.0516 0.1536 0.1536
Onchocerca volvulus 0.0126 0.003 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Echinococcus multilocularis calcium dependent protein kinase 0.0131 0.0052 0.0052
Trypanosoma brucei polo-like protein kinase 0.0521 0.1555 0.1533
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0131 0.0049 0.0049
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0235 0.0451 0.0426
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0939 0.3168 1
Echinococcus granulosus cyclin dependent kinase 5 0.0228 0.0426 0.0426
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0228 0.0426 0.04
Echinococcus multilocularis netrin receptor unc 5 0.0211 0.0358 0.0358
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0267 0.0576 0.0576
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0249 0.0507 0.0507
Schistosoma mansoni septate junction protein 0.0155 0.0142 0.0142
Entamoeba histolytica protein kinase, putative 0.0563 0.1718 0.8948
Entamoeba histolytica hypothetical protein 0.0366 0.0956 0.4934
Plasmodium falciparum calcium-dependent protein kinase 2 0.0193 0.0292 0.0266
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0171 0.0145
Giardia lamblia Kinase, CMGC CLK 0.0296 0.0685 0.185
Onchocerca volvulus 0.0506 0.1496 0.5694
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0379 0.0379
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Echinococcus multilocularis tyrosine protein kinase HCK 0.0176 0.0223 0.0223
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Sushi domain 0.0506 0.1496 0.1496
Leishmania major casein kinase, putative 0.0209 0.035 0.0324
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0316 0.0763 0.0763
Echinococcus granulosus protein jagged 2 0.0274 0.0602 0.0602
Loa Loa (eye worm) AGC/NDR protein kinase 0.031 0.0739 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.035 0.035
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0217 0.0382 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0416 0.115 0.115
Plasmodium falciparum casein kinase 2, alpha subunit 0.0192 0.0286 0.0261
Echinococcus multilocularis twitchin 0.0193 0.0289 0.0289
Echinococcus multilocularis lachesin 0.0285 0.0646 0.0646
Trichomonas vaginalis STE family protein kinase 0.0162 0.0171 0.0481
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.0499 0.2528
Echinococcus multilocularis thioredoxin glutathione reductase 0.2711 1 1
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Schistosoma mansoni neuroglian 0.0303 0.0713 0.0713
Schistosoma mansoni g1/s-specific cyclin C 0.1221 0.4256 0.4256
Echinococcus multilocularis Immunoglobulin subtype 0.0155 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0249 0.0507 0.0507
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0155 0.0142 0.0142
Plasmodium falciparum thioredoxin reductase 0.2711 1 1
Echinococcus multilocularis myosin iiia 0.0162 0.0171 0.0171
Echinococcus granulosus casein kinase I alpha 0.0209 0.035 0.035
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Schistosoma mansoni nephrin 0.0664 0.2107 0.2107
Echinococcus granulosus casein kinase i 0.0209 0.035 0.035
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0644 0.2029 0.2029
Echinococcus granulosus homeodomain interacting protein kinase 3 0.039 0.1051 0.1051
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0472 0.1367 0.1367
Brugia malayi Cadherin domain containing protein 0.0274 0.0602 0.0602
Echinococcus granulosus cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0545 0.0545
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.182 0.6564 0.6564
Brugia malayi Protein kinase domain containing protein 0.068 0.2169 0.2169
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0285 0.0646 0.0646
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0249 0.0507 0.0482
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0419 0.1162 0.1162
Brugia malayi basement membrane proteoglycan precursor 0.0155 0.0142 0.0142
Onchocerca volvulus Peroxidasin homolog 0.0131 0.0049 0.0146
Trypanosoma cruzi trypanothione reductase, putative 0.2711 1 1
Entamoeba histolytica protein kinase, putative 0.0235 0.0451 0.2275
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0249 0.0507 0.0482
Plasmodium falciparum glutathione reductase 0.2711 1 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.016 0.0164 0.0138
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0225 0.0414 0.0414
Loa Loa (eye worm) TK/ALK protein kinase 0.029 0.0664 0.0664
Schistosoma mansoni hypothetical protein 0.0249 0.0507 0.0507
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0296 0.0685 0.0661
Trypanosoma brucei aurora B kinase 0.0225 0.0414 0.0389
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Trypanosoma brucei rac serine-threonine kinase, putative 0.0563 0.1718 0.1696
Brugia malayi Protein kinase domain containing protein 0.031 0.0739 0.0739
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Echinococcus granulosus growth factor receptor bound protein 2 0.012 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.021 0.0356 0.0356
Schistosoma mansoni disulfide oxidoreductase 0.0249 0.0507 0.0507
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0131 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0344 0.0872 0.2707
Echinococcus granulosus tyrosine protein kinase ABL1 0.0126 0.003 0.003
Onchocerca volvulus 0.0274 0.0602 0.2265
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0193 0.0292 0.0292
Echinococcus multilocularis Protein kinase C, brain isozyme 0.047 0.1356 0.1356
Echinococcus multilocularis tyrosine protein kinase shark 0.0331 0.0823 0.0823
Toxoplasma gondii rhoptry neck protein RON1 0.0506 0.1496 0.1474
Echinococcus multilocularis roundabout 2 0.0819 0.2703 0.2703
Giardia lamblia Kinase, CMGC CDK 0.0228 0.0426 0.0997
Schistosoma mansoni tyrosine kinase 0.0384 0.1028 0.1028
Loa Loa (eye worm) AGC/AKT protein kinase 0.0563 0.1718 0.1718
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0761 0.2479 0.2479
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0939 0.3168 1
Brugia malayi C1-like domain containing protein 0.0419 0.1162 0.1162
Trypanosoma cruzi trypanothione reductase, putative 0.0939 0.3168 0.315
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus granulosus tyrosine protein kinase 0.0293 0.0676 0.0676
Echinococcus granulosus Protein kinase C brain isozyme 0.047 0.1356 0.1356
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0356 0.0356
Schistosoma mansoni serine/threonine protein kinase 0.0627 0.1964 0.1964
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase Abl 0.018 0.0241 0.0241
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0193 0.029 0.029
Echinococcus granulosus tyrosine protein kinase HCK 0.0176 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0148 0.0116 0.0116
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0939 0.3168 0.3168
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.0602 0.0602
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Loa Loa (eye worm) TK/ABL protein kinase 0.0126 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Echinococcus granulosus roundabout 2 0.0303 0.0713 0.0713
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0249 0.0507 0.2569
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0235 0.0451 0.0426
Loa Loa (eye worm) disorganized muscle protein 1 0.0131 0.0049 0.0049
Loa Loa (eye worm) CAMK protein kinase 0.021 0.0356 0.0356
Onchocerca volvulus Peroxidasin homolog 0.0131 0.0051 0.0153
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0329 0.0815 0.0815
Trichomonas vaginalis CAMK family protein kinase 0.0243 0.0482 0.147
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0149 0.0122 0.0096
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Brugia malayi Myb-like DNA-binding domain containing protein 0.0131 0.0049 0.0049
Echinococcus granulosus twitchin 0.0709 0.2279 0.2279
Brugia malayi hypothetical protein 0.0126 0.003 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0382 0.0382
Loa Loa (eye worm) hypothetical protein 0.0166 0.0186 0.0186
Echinococcus granulosus tyrosine protein kinase Srms 0.0518 0.1543 0.1543
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0425 0.1186 0.1186
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Plasmodium falciparum thioredoxin reductase 0.0939 0.3168 0.315
Entamoeba histolytica serine/threonine protein kinase, putative 0.0149 0.0122 0.0539
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0225 0.0413 0.0413
Brugia malayi glutamate synthase 0.0249 0.0507 0.0507
Onchocerca volvulus 0.0172 0.0209 0.0759
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0296 0.0685 0.0685
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0193 0.0292 0.0172
Loa Loa (eye worm) TK protein kinase 0.0176 0.0223 0.0223
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0171 0.0145
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0239 0.0466 0.0466
Loa Loa (eye worm) TK/ROR protein kinase 0.0193 0.029 0.029
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0225 0.0414 0.2078
Schistosoma mansoni laminin gamma-3 chain 0.0274 0.0602 0.0602
Trypanosoma brucei cdc2-related kinase 1 0.0228 0.0426 0.04
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.018 0.0241 0.0241
Echinococcus multilocularis hemicentin 1 0.0285 0.0646 0.0646
Schistosoma mansoni tyrosine kinase 0.0293 0.0677 0.0677
Loa Loa (eye worm) thyroid receptor interactor 0.0197 0.0307 0.0307
Echinococcus multilocularis cyclin 0.0606 0.1884 0.1884
Echinococcus granulosus slit 2 protein 0.0317 0.0767 0.0767
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.016 0.0164 0.0138
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0131 0.0051 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Brugia malayi Prion-like- 0.0285 0.0646 0.0646
Echinococcus multilocularis titin 0.0131 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0685 0.0685
Schistosoma mansoni kinase 0.0557 0.1693 0.1693
Echinococcus granulosus hemicentin 1 0.0285 0.0646 0.0646
Echinococcus multilocularis neuroglian 0.0647 0.2039 0.2039
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0225 0.0414 0.0296
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0608 0.189 0.189
Trichomonas vaginalis AGC family protein kinase 0.0262 0.0555 0.1701
Onchocerca volvulus 0.0131 0.0049 0.0146
Brugia malayi Disorganized muscle protein 1 0.0131 0.0049 0.0049
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0437 0.1231 0.1231
Echinococcus granulosus epidermal growth factor receptor 0.0663 0.2104 0.2104
Echinococcus granulosus serine:threonine protein kinase 0.0219 0.0391 0.0391
Echinococcus multilocularis mitogen activated protein kinase 11 0.0306 0.0726 0.0726
Entamoeba histolytica protein kinase, putative 0.0193 0.0292 0.1434
Plasmodium vivax thioredoxin reductase, putative 0.2711 1 1
Echinococcus multilocularis roundabout 2 0.0303 0.0713 0.0713
Entamoeba histolytica cell division protein kinase 2, putative 0.0228 0.0426 0.214
Schistosoma mansoni tyrosine kinase 0.0577 0.1769 0.1769
Toxoplasma gondii AGC kinase 0.0217 0.0382 0.0357
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0193 0.0292 0.0266
Echinococcus granulosus protein kinase 0.0295 0.0682 0.0682
Brugia malayi MAP kinase sur-1 0.016 0.0164 0.0164
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0303 0.0713 0.0713
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus multilocularis protein kinase c epsilon type 0.0393 0.1061 0.1061
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0147 0.0406
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0147 0.0406
Schistosoma mansoni c4b-binding protein beta chain 0.0506 0.1496 0.1496
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0292 0.0292
Echinococcus granulosus cGMP dependent protein kinase 0.016 0.0163 0.0163
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0242 0.0479 0.0479
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0249 0.0507 0.1549
Loa Loa (eye worm) hypothetical protein 0.0578 0.1774 0.1774
Echinococcus multilocularis casein kinase I gamma 0.0411 0.113 0.113
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0939 0.3168 0.315
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0761 0.2479 0.2479
Echinococcus granulosus dual specificity 0.0267 0.0576 0.0576
Schistosoma mansoni septate junction protein 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0329 0.0815 0.2528
Trypanosoma cruzi NADH dehydrogenase, putative 0.0249 0.0507 0.0482
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0419 0.1162 0.1162
Onchocerca volvulus 0.0604 0.1874 0.7144
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0249 0.0507 0.0482
Loa Loa (eye worm) AUR protein kinase 0.0225 0.0414 0.0414
Trypanosoma brucei NADH dehydrogenase 0.0249 0.0507 0.0482
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Trypanosoma cruzi Protein kinase B 0.0316 0.0764 0.074
Giardia lamblia Kinase, NEK 0.0262 0.0555 0.1422
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0713 0.0713
Plasmodium falciparum apical sushi protein 0.0506 0.1496 0.1474
Loa Loa (eye worm) hypothetical protein 0.0268 0.058 0.058
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0267 0.0575 0.1766
Onchocerca volvulus 0.0506 0.1496 0.5694
Toxoplasma gondii rhoptry neck protein RON9 0.0506 0.1496 0.1474
Loa Loa (eye worm) TK/EGFR protein kinase 0.0663 0.2104 0.2104
Brugia malayi Protein kinase domain containing protein 0.0329 0.0815 0.0815
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus multilocularis ephrin type A receptor 4 A 0.0186 0.0264 0.0264
Trichomonas vaginalis AGC family protein kinase 0.031 0.0739 0.2287
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Schistosoma mansoni protein kinase C mu 0.0419 0.1162 0.1162
Loa Loa (eye worm) TK protein kinase 0.048 0.1397 0.1397
Echinococcus granulosus protein jagged 1 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0209 0.0602
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0249 0.0507 0.1549
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0247 0.0499 0.0474
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Giardia lamblia Kinase, CMGC CK2 0.0192 0.0286 0.054
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.016 0.0164 0.0138
Echinococcus granulosus casein kinase I alpha 0.0209 0.035 0.035
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.039 0.1051 0.1051
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0209 0.035 0.035
Echinococcus granulosus neural cadherin 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0193 0.0292 0.0292
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0125 0.0029 0.0052
Echinococcus granulosus cyclin dependent kinase 1 0.0228 0.0426 0.0426
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0172 0.0209 0.0209
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.035 0.0893 0.0893
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0939 0.3168 0.3168
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0146 0.011 0.0084
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.0602 0.0602
Echinococcus multilocularis neuroglian 0.0303 0.0713 0.0713
Echinococcus granulosus activin receptor type 0.0125 0.0026 0.0026
Onchocerca volvulus 0.0249 0.0507 0.1902
Brugia malayi hypothetical protein 0.0216 0.0379 0.0379
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0155 0.0144 0.0118
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Echinococcus multilocularis cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Echinococcus granulosus protein kinase c iota type 0.0551 0.167 0.167
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0763 0.0763
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0685 0.2115
Echinococcus multilocularis mitogen activated protein kinase 14 0.0306 0.0726 0.0726
Echinococcus multilocularis casein kinase ii subunit alpha 0.0192 0.0286 0.0286
Trichomonas vaginalis STE family protein kinase 0.0262 0.0555 0.1701
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0472 0.1367 0.1367
Loa Loa (eye worm) hypothetical protein 0.0173 0.0211 0.0211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Onchocerca volvulus 0.0124 0.0023 0.0045
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0193 0.0292 0.0172
Giardia lamblia Kinase, CMGC DYRK 0.0267 0.0576 0.1491
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0162 0.0171 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0382 0.0382
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0249 0.0507 0.0482
Echinococcus granulosus tyrosine protein kinase Src64B 0.0293 0.0677 0.0677
Echinococcus multilocularis casein kinase I alpha 0.0209 0.035 0.035
Echinococcus multilocularis serine:threonine protein kinase 3 0.0495 0.1455 0.1455
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Echinococcus granulosus aurora kinase A 0.0225 0.0414 0.0414
Echinococcus multilocularis serine:threonine protein kinase N2 0.0251 0.0512 0.0512
Echinococcus granulosus serine/threonine protein kinase 0.0316 0.0764 0.0764
Brugia malayi Peroxidasin 0.0286 0.0648 0.0648
Giardia lamblia Kinase, NEK 0.0262 0.0555 0.1422
Schistosoma mansoni tyrosine kinase 0.0463 0.1331 0.1331
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0249 0.0507 0.0482
Trichomonas vaginalis AGC family protein kinase 0.0217 0.0382 0.1153
Entamoeba histolytica protein kinase, putative 0.0165 0.0181 0.0852
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus multilocularis dual specificity 0.0267 0.0576 0.0576
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0426 0.129
Trypanosoma cruzi hypothetical protein, conserved 0.0249 0.0507 0.0482
Schistosoma mansoni cell adhesion molecule 0.0303 0.0713 0.0713
Onchocerca volvulus Putative titin 0.0131 0.0049 0.0146
Echinococcus multilocularis titin 0.0131 0.0049 0.0049
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0209 0.035 0.0324
Loa Loa (eye worm) TK/FAK protein kinase 0.0555 0.1687 0.1687
Schistosoma mansoni hypothetical protein 0.0216 0.0379 0.0379
Brugia malayi Animal haem peroxidase family protein 0.0131 0.0049 0.0049
Onchocerca volvulus 0.0372 0.0979 0.3711
Brugia malayi Serine/threonine-protein kinase SULU 0.0428 0.1197 0.1197
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0217 0.0382 0.0357
Echinococcus multilocularis protein jagged 1 0.0274 0.0602 0.0602
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0164 0.0138
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0387 0.1036 0.1036
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0939 0.3168 1
Brugia malayi protein-tyrosine kinase 0.0239 0.0466 0.0466
Echinococcus multilocularis nervana 2 0.0239 0.0468 0.0468
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0521 0.1555 0.1555
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0163 0.0163
Loa Loa (eye worm) AGC/PKG protein kinase 0.016 0.0163 0.0163
Leishmania major protein kinase A catalytic subunit 0.0217 0.0382 0.0357
Schistosoma mansoni protein kinase 0.0123 0.0019 0.0019
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0144 0.0101 0.0101
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0156 0.0147 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.056 0.1706 0.1706
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0939 0.3168 0.3168
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0267 0.0576 0.0551
Brugia malayi Thioredoxin reductase 0.2711 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Onchocerca volvulus 0.0506 0.1496 0.5694
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0026 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0142 0.0142
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0278 0.0619 0.0619
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0247 0.0499 0.0474
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0296 0.0685 0.0661
Echinococcus multilocularis 0.0131 0.0049 0.0049
Brugia malayi Protein kinase domain containing protein 0.0866 0.2885 0.2885
Entamoeba histolytica protein kinase , putative 0.0225 0.0414 0.2078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Brugia malayi Protein kinase domain containing protein 0.0172 0.0209 0.0209
Schistosoma mansoni septate junction protein 0.0285 0.0646 0.0646
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0249 0.0507 0.2569
Echinococcus granulosus serine threonine protein kinase nrc 0.0301 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Loa Loa (eye worm) AUR protein kinase 0.0225 0.0414 0.0414
Echinococcus multilocularis hypothetical protein 0.0197 0.0305 0.0305
Plasmodium vivax casein kinase 1, putative 0.0209 0.035 0.0231
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.0602 0.0602
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0499 0.1524
Echinococcus granulosus tyrosine protein kinase Src42A 0.0178 0.0233 0.0233
Schistosoma mansoni tyrosine kinase 0.0123 0.002 0.002
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0418 0.1156 0.1156
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0296 0.0685 0.0661
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Plasmodium falciparum protein serine/threonine kinase-1 0.0296 0.0685 0.0661
Onchocerca volvulus 0.0274 0.0602 0.2265
Echinococcus granulosus notch 0.0274 0.0602 0.0602
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0708 0.2275 0.2275
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0193 0.0292 0.0266
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Schistosoma mansoni serine/threonine protein kinase 0.0393 0.1061 0.1061
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0217 0.0382 0.0357
Trypanosoma brucei protein kinase, putative 0.016 0.0164 0.0138

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 18 % Inhibition of FimC/FimH pilus assembly complex formation in Escherichia coli at 10 uM ChEMBL. 15715464
Inhibition (binding) = 32 % Inhibition of FimC/FimH pilus assembly complex formation in Escherichia coli at 50 uM ChEMBL. 15715464
Inhibition (binding) = 50 % Inhibition of FimC/FimH pilus assembly complex formation in Escherichia coli at 200 uM ChEMBL. 15715464

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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