Detailed information for compound 313778

Basic information

Technical information
  • TDR Targets ID: 313778
  • Name: 7-bromo-8-methoxy-2,3,4,5-tetrahydro-1H-3-ben zazepine
  • MW: 256.139 | Formula: C11H14BrNO
  • H donors: 1 H acceptors: 0 LogP: 2.45 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2CCNCCc2cc1Br
  • InChi: 1S/C11H14BrNO/c1-14-11-7-9-3-5-13-4-2-8(9)6-10(11)12/h6-7,13H,2-5H2,1H3
  • InChiKey: GDBBQVJRKVPDDA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
Brugia malayi Serotonin receptor Get druggable targets OG5_135430 All targets in OG5_135430
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0573
Schistosoma mansoni nephrin related 0.0163 0.0224 0.0224
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0219 0.0425 0.0335
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0265 0.0591 0.0547
Brugia malayi Fibronectin type III domain containing protein 0.0558 0.1648 0.1632
Mycobacterium ulcerans NADH dehydrogenase 0.0265 0.0591 0.1711
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Trypanosoma cruzi hypothetical protein, conserved 0.0265 0.0591 0.0573
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0265 0.0591 0.0547
Onchocerca volvulus Neurogenic locus notch homolog 0.0291 0.0685 0.2636
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0164 0.0228 0.0824
Loa Loa (eye worm) TK/FER protein kinase 0.042 0.115 0.1144
Echinococcus granulosus cyclin dependent kinase 0.023 0.0465 0.0465
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0223 0.0439 0.0439
Trypanosoma brucei NADH dehydrogenase 0.0265 0.0591 0.0502
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0297 0.0708 0.062
Echinococcus multilocularis neurogenic locus notch protein 0.0291 0.0685 0.0685
Mycobacterium ulcerans dehydrogenase 0.0265 0.0591 0.1711
Schistosoma mansoni tyrosine kinase 0.0386 0.1029 0.1029
Echinococcus multilocularis hypothetical protein 0.0197 0.0347 0.0347
Echinococcus granulosus mitogen activated protein kinase 14 0.0308 0.0746 0.0746
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.03 0.0717 0.0717
Echinococcus multilocularis conserved hypothetical protein 0.0833 0.2639 0.2639
Loa Loa (eye worm) AGC/PKG protein kinase 0.0162 0.0222 0.0216
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Brugia malayi Sushi domain 0.0537 0.1571 0.1555
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0865 0.2754 0.274
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0245 0.0519 0.0512
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0241 0.0504 0.144
Echinococcus granulosus serine:threonine protein kinase N2 0.0251 0.054 0.054
Trichomonas vaginalis glutathione reductase, putative 0.0997 0.3229 1
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0269 0.0606 0.0588
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.0433 0.0433
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Onchocerca volvulus 0.0276 0.0632 0.2424
Echinococcus granulosus protein tyrosine kinase 0.0553 0.1629 0.1629
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0127 0.0096 0.0003
Entamoeba histolytica protein kinase, putative 0.0195 0.034 0.1232
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.1274 0.1274
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0395 0.1203
Echinococcus granulosus NDR protein kinase 0.0311 0.0759 0.0759
Schistosoma mansoni protein kinase 0.0839 0.2658 0.2658
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0415 0.0415
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1405 0.4697 0.4697
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0265 0.0591 0.0591
Entamoeba histolytica protein kinase, putative 0.0161 0.0217 0.0785
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Schistosoma mansoni hypothetical protein 0.0154 0.0194 0.0194
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0465 0.1423
Schistosoma mansoni tyrosine kinase 0.0402 0.1087 0.1087
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0265 0.0591 0.0591
Onchocerca volvulus 0.0628 0.1901 0.7491
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0162 0.0221 0.0129
Onchocerca volvulus 0.0291 0.0685 0.2636
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.0439 0.1342
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0388 0.1036 0.1029
Giardia lamblia Aurora kinase 0.0227 0.0456 0.1165
Loa Loa (eye worm) hypothetical protein 0.0173 0.0259 0.0252
Echinococcus granulosus protein kinase shaggy 0.0249 0.0534 0.0534
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Loa Loa (eye worm) hypothetical protein 0.0154 0.0194 0.0187
Trichomonas vaginalis STE family protein kinase 0.0164 0.0228 0.0685
Loa Loa (eye worm) cyclin C 0.1709 0.5793 0.579
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0465 0.1423
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0126 0.0092 0.0333
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Echinococcus multilocularis casein kinase I alpha 0.021 0.0395 0.0395
Brugia malayi Protein kinase domain containing protein 0.0271 0.0613 0.0596
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0265 0.0591 0.214
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Echinococcus granulosus cyclin dependent kinase 9 0.0156 0.0198 0.0198
Brugia malayi Egg laying defective protein 4 0.0162 0.0222 0.0204
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Loa Loa (eye worm) gastrulation defective protein 1 0.1082 0.3534 0.353
Schistosoma mansoni tyrosine kinase 0.0465 0.1312 0.1312
Echinococcus multilocularis cyclin dependent kinase 0.023 0.0465 0.0465
Echinococcus multilocularis Immunoglobulin 0.0163 0.0224 0.0224
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0174 0.0263 0.0257
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0265 0.0591 0.0547
Giardia lamblia Kinase, NEK 0.0263 0.0586 0.158
Schistosoma mansoni serine/threonine-protein kinase 0.0317 0.0781 0.0781
Onchocerca volvulus 0.0123 0.0079 0.0218
Loa Loa (eye worm) TK/INSR protein kinase 0.0578 0.1721 0.1715
Loa Loa (eye worm) TK/FAK protein kinase 0.0559 0.165 0.1644
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0541 0.1585 0.1585
Echinococcus multilocularis casein kinase I alpha 0.021 0.0395 0.0395
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Brugia malayi serine/threonine-protein kinase 6 0.0227 0.0456 0.0438
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0997 0.3229 0.3197
Loa Loa (eye worm) hypothetical protein 0.0173 0.0259 0.0252
Brugia malayi SH2 domain containing protein 0.0126 0.0092 0.0073
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.023 0.0465 0.0459
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni serine/threonine protein kinase 0.0681 0.2092 0.2092
Trypanosoma cruzi NADH dehydrogenase, putative 0.0265 0.0591 0.0573
Toxoplasma gondii AGC kinase 0.0219 0.0425 0.0381
Loa Loa (eye worm) casein kinase 0.0348 0.0892 0.0886
Echinococcus granulosus protein kinase c epsilon type 0.0394 0.1058 0.1058
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0424 0.0406
Plasmodium falciparum calcium-dependent protein kinase 5 0.0195 0.034 0.0295
Brugia malayi Protein kinase domain containing protein 0.0158 0.0205 0.0187
Plasmodium vivax apical sushi protein, putative 0.0537 0.1571 0.1532
Schistosoma mansoni tyrosine kinase 0.0123 0.0082 0.0082
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.028 0.0646 0.0646
Echinococcus multilocularis tyrosine protein kinase Fyn 0.024 0.0501 0.0501
Entamoeba histolytica protein kinase, putative 0.0227 0.0456 0.165
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0137 0.0131 0.0131
Onchocerca volvulus Serine\/threonine kinase homolog 0.0317 0.078 0.3018
Brugia malayi Immunoglobulin domain containing protein 0.0163 0.0224 0.0206
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Entamoeba histolytica protein kinase 2, putative 0.0303 0.0728 0.2639
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Trypanosoma brucei Casein kinase II 0.0194 0.0335 0.0244
Loa Loa (eye worm) hypothetical protein 0.0154 0.0194 0.0187
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0245 0.0519 0.0519
Echinococcus granulosus casein kinase I gamma 0.0412 0.1122 0.1122
Echinococcus multilocularis mitogen activated protein kinase 0.0162 0.0221 0.0221
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.02 0.0356 0.0356
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0522 0.1519 0.1519
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0144 0.0157 0.0157
Plasmodium falciparum glycogen synthase kinase 3 0.0249 0.0534 0.049
Brugia malayi MAP kinase sur-1 0.0162 0.0221 0.0203
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.021 0.0395 0.0388
Echinococcus multilocularis mitogen activated protein kinase 11 0.0308 0.0746 0.0746
Trypanosoma cruzi hypothetical protein, conserved 0.0265 0.0591 0.0573
Loa Loa (eye worm) TK protein kinase 0.024 0.0501 0.0494
Schistosoma mansoni ephrin receptor 0.0186 0.0309 0.0309
Schistosoma mansoni titin 0.0154 0.0194 0.0194
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Trichomonas vaginalis AGC family protein kinase 0.0263 0.0586 0.1797
Echinococcus granulosus insulin receptor 0.0578 0.1721 0.1721
Echinococcus granulosus fibroblast growth factor receptor 4 0.035 0.0899 0.0899
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0161 0.0217 0.0125
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0126 0.009 0.0071
Schistosoma mansoni disulfide oxidoreductase 0.0265 0.0591 0.0591
Echinococcus granulosus roundabout 2 0.0858 0.2727 0.2727
Schistosoma mansoni protein kinase 0.0427 0.1176 0.1176
Trichomonas vaginalis CMGC family protein kinase 0.0297 0.0708 0.2175
Echinococcus granulosus raf serine:threonine protein kinase 0.0143 0.0154 0.0154
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0361 0.0937 0.0931
Loa Loa (eye worm) notch protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0265 0.0591 0.0502
Loa Loa (eye worm) hypothetical protein 0.0597 0.1788 0.1782
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0294 0.0698 0.0698
Schistosoma mansoni sulfide quinone reductase 0.0265 0.0591 0.0591
Echinococcus granulosus casein kinase i 0.021 0.0395 0.0395
Brugia malayi Cadherin domain containing protein 0.0291 0.0685 0.0667
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.0439 0.1342
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Onchocerca volvulus 0.0537 0.1571 0.6174
Loa Loa (eye worm) TK protein kinase 0.0295 0.07 0.0693
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0195 0.034 0.0322
Echinococcus granulosus serine:threonine protein kinase N2 0.0562 0.1661 0.1661
Brugia malayi Cam kinase protein 1 0.0195 0.034 0.0322
Brugia malayi protein unc-22 0.0218 0.0424 0.0406
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0997 0.3229 1
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0311 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Echinococcus multilocularis serine:threonine protein kinase N2 0.0562 0.1661 0.1661
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Echinococcus granulosus dual specificity 0.0269 0.0606 0.0606
Loa Loa (eye worm) CAMK/PKD protein kinase 0.034 0.0862 0.0855
Schistosoma mansoni tyrosine kinase 0.0667 0.2038 0.2038
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.023 0.0465 0.0459
Echinococcus multilocularis down syndrome cell adhesion 0.0137 0.0131 0.0131
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0421 0.1153 0.1136
Plasmodium vivax casein kinase 1, putative 0.021 0.0395 0.035
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Loa Loa (eye worm) hypothetical protein 0.0317 0.078 0.0774
Loa Loa (eye worm) hypothetical protein 0.0579 0.1724 0.1719
Plasmodium falciparum apical sushi protein 0.0537 0.1571 0.1532
Echinococcus granulosus neurogenic locus notch protein 0.0291 0.0685 0.0685
Echinococcus multilocularis tyrosine protein kinase Abl 0.0181 0.0289 0.0289
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Entamoeba histolytica cyclin C, putative 0.0867 0.2761 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Echinococcus granulosus nervana 2 0.0239 0.0498 0.0498
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Mycobacterium tuberculosis Conserved hypothetical protein 0.0127 0.0096 0.005
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0654 0.1994 0.1988
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi pregnancy-associated plasma protein-A 0.0537 0.1571 0.1555
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0263 0.0263
Echinococcus multilocularis cyclin dependent kinase 19 0.1146 0.3764 0.3764
Echinococcus granulosus cyclin dependent kinase 19 0.1146 0.3764 0.3764
Echinococcus granulosus cyclin dependent kinase 1 0.023 0.0465 0.0465
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0421 0.1153 0.1147
Loa Loa (eye worm) hypothetical protein 0.0558 0.1648 0.1642
Toxoplasma gondii selenide, water dikinase 0.0265 0.0591 0.0547
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Echinococcus granulosus tyrosine protein kinase Fps85D 0.042 0.115 0.115
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0236 0.0489 0.0399
Loa Loa (eye worm) thyroid receptor interactor 0.0197 0.0349 0.0342
Brugia malayi Protein kinase domain containing protein 0.182 0.6194 0.6187
Brugia malayi glutamate synthase 0.0265 0.0591 0.0573
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Schistosoma mansoni cell adhesion molecule 0.0721 0.2234 0.2234
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0194 0.0187
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0265 0.0591 0.0547
Echinococcus multilocularis casein kinase i 0.021 0.0395 0.0395
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Onchocerca volvulus 0.0137 0.0131 0.0425
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0997 0.3229 0.3197
Loa Loa (eye worm) animal heme peroxidase 0.0137 0.0131 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Brugia malayi Protein kinase domain containing protein 0.0681 0.2092 0.2077
Schistosoma mansoni protein kinase 0.0373 0.098 0.098
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3165
Echinococcus multilocularis neurogenic locus protein delta 0.0291 0.0685 0.0685
Schistosoma mansoni g1/s-specific cyclin C 0.1709 0.5793 0.5793
Brugia malayi Temporarily assigned gene name protein 59 0.0249 0.0536 0.0518
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0163 0.0224 0.0224
Trypanosoma cruzi polo-like protein kinase, putative 0.0522 0.1519 0.1503
Echinococcus granulosus slit 2 protein 0.0334 0.0839 0.0839
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0265 0.0591 0.0547
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0265 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus granulosus tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Brugia malayi hypothetical protein 0.0558 0.1648 0.1632
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0465 0.0465
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0523 0.1895
Echinococcus granulosus epidermal growth factor receptor 0.0667 0.2038 0.2038
Echinococcus granulosus aurora kinase A 0.0227 0.0456 0.0456
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0249 0.0534 0.0534
Plasmodium vivax glycogen synthase kinase 3, putative 0.0249 0.0534 0.049
Entamoeba histolytica PH domain containing protein kinase, putative 0.0233 0.0478 0.173
Echinococcus multilocularis serine:threonine protein kinase 3 0.0496 0.1426 0.1426
Onchocerca volvulus 0.0371 0.0976 0.3796
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0137 0.0131 0.0131
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0445 0.124 0.1223
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0474 0.1344 0.1344
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Echinococcus granulosus tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Trichomonas vaginalis AGC family protein kinase 0.0174 0.0263 0.0796
Brugia malayi basement membrane proteoglycan 0.0163 0.0224 0.0206
Loa Loa (eye worm) hypothetical protein 0.0216 0.0415 0.0409
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0265 0.0591 0.0547
Giardia lamblia Kinase, AGC AKT 0.0226 0.0453 0.1157
Mycobacterium tuberculosis Probable reductase 0.0265 0.0591 0.0547
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni protein kinase 0.0427 0.1176 0.1176
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0249 0.0534 0.0516
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0415 0.0397
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.042 0.115 0.115
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0297 0.0708 0.069
Brugia malayi Variant SH3 domain containing protein 0.0118 0.0064 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0465 0.1423
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0311 0.0759 0.0759
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.023 0.0465 0.0465
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0284 0.0662 0.2034
Echinococcus granulosus titin 0.0137 0.0131 0.0131
Toxoplasma gondii histone kinase SNF1, putative 0.0151 0.0182 0.0137
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0162 0.0221 0.0203
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0445 0.124 0.124
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0361 0.0937 0.0937
Loa Loa (eye worm) CDC7 protein kinase 0.0174 0.0263 0.0256
Brugia malayi Sex muscle abnormal protein 5 0.0118 0.0064 0.0045
Echinococcus multilocularis neurogenic locus notch protein 0.0291 0.0685 0.0685
Echinococcus multilocularis hemicentin 1 0.03 0.0717 0.0717
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0265 0.0591 0.0547
Brugia malayi kettin 0.0137 0.0131 0.0112
Echinococcus multilocularis neurogenic locus notch protein 4 0.0291 0.0685 0.0685
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.0285 0.0267
Brugia malayi Muscle positioning protein 4 0.0291 0.0685 0.0667
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0216 0.0415 0.0415
Trichomonas vaginalis AGC family protein kinase 0.0158 0.0205 0.0616
Loa Loa (eye worm) hypothetical protein 0.0118 0.0064 0.0057
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Echinococcus granulosus c4b binding protein beta chain 0.0537 0.1571 0.1571
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0308 0.0746 0.0739
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.035 0.0899 0.0899
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0265 0.0591 0.1711
Onchocerca volvulus 0.0265 0.0591 0.2261
Giardia lamblia Kinase, CMGC GSK 0.0249 0.0534 0.1414
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Schistosoma mansoni vam6/vps39 related 0.0216 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni titin 0.03 0.0717 0.0717
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi casein kinase 1, delta 0.021 0.0395 0.0377
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Leishmania major NADH dehydrogenase, putative 0.0265 0.0591 0.0502
Loa Loa (eye worm) hypothetical protein 0.0357 0.0923 0.0916
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0297 0.0708 0.062
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus 0.0137 0.0131 0.0425
Schistosoma mansoni myosin-binding protein-related 0.0154 0.0194 0.0194
Brugia malayi GCC2 and GCC3 family protein 0.0827 0.2618 0.2604
Loa Loa (eye worm) hypothetical protein 0.084 0.2664 0.2659
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.018 0.0285 0.0278
Echinococcus multilocularis casein kinase I delta 0.021 0.0395 0.0395
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0195 0.034 0.0295
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.023 0.0465 0.0459
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Brugia malayi RhoGAP domain containing protein 0.0144 0.0157 0.0139
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0265 0.0591 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Echinococcus multilocularis calcium activated potassium channel 0.0261 0.0577 0.0577
Schistosoma mansoni basigin related 0.0163 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Schistosoma mansoni cell adhesion molecule 0.0163 0.0224 0.0224
Brugia malayi Protein kinase domain containing protein 0.0221 0.0433 0.0415
Echinococcus granulosus casein kinase I delta 0.021 0.0395 0.0395
Giardia lamblia Kinase, CMGC GSK 0.0249 0.0534 0.1414
Echinococcus multilocularis tyrosine protein kinase 0.0295 0.07 0.07
Schistosoma mansoni slit 0.0137 0.0133 0.0133
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0732 0.2275 0.2261
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0164 0.0227 0.0227
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0465 0.1312 0.1312
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0019 0.0019
Echinococcus granulosus protein kinase c iota type 0.0552 0.1627 0.1627
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.1036 0.1036
Schistosoma mansoni kinase 0.0558 0.1648 0.1648
Leishmania major protein kinase, putative 0.0227 0.0456 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Onchocerca volvulus 0.0268 0.0604 0.2312
Leishmania major protein kinase A catalytic subunit isoform 1 0.0219 0.0425 0.0335
Loa Loa (eye worm) hypothetical protein 0.0232 0.0474 0.0467
Leishmania major trypanothione reductase 0.2877 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0317 0.078 0.0763
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Loa Loa (eye worm) AGC/NDR protein kinase 0.0311 0.0759 0.0752
Plasmodium falciparum calcium-dependent protein kinase 3 0.0195 0.034 0.0295
Brugia malayi EGF-like domain containing protein 0.0334 0.0839 0.0822
Trypanosoma brucei protein kinase, putative 0.0249 0.0534 0.0445
Echinococcus multilocularis serine:threonine protein kinase N2 0.0251 0.054 0.054
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0388 0.1035 0.1035
Loa Loa (eye worm) one IG domain family member 0.0137 0.0131 0.0124
Loa Loa (eye worm) hypothetical protein 0.0197 0.0347 0.034
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0294 0.0698 0.0698
Loa Loa (eye worm) TK/EPH protein kinase 0.022 0.0431 0.0424
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0997 0.3229 1
Trypanosoma cruzi casein kinase II, putative 0.0194 0.0335 0.0317
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0865 0.2754 0.2754
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0534 0.1636
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0709 0.2191 0.2185
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0577 0.0577
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0708 0.0708
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Brugia malayi map kinase activated protein kinase protein 2 0.0762 0.2382 0.2367
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Plasmodium vivax ferrodoxin reductase, putative 0.0265 0.0591 0.0547
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0419 0.1148 0.1142
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.0311 0.0759 0.0759
Brugia malayi Protein kinase domain containing protein 0.0867 0.276 0.2746
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0326 0.0813 0.0813
Trypanosoma cruzi polo-like protein kinase, putative 0.0522 0.1519 0.1503
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0474 0.1344 0.1338
Giardia lamblia Kinase, CMGC MAPK 0.0162 0.0221 0.0418
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Giardia lamblia Kinase, CMGC CK2 0.0194 0.0335 0.0781
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0577 0.0577
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Trypanosoma cruzi NADH dehydrogenase, putative 0.0265 0.0591 0.0573
Echinococcus granulosus Immunoglobulin 0.0163 0.0224 0.0224
Echinococcus multilocularis serine:threonine protein kinase 38 0.0311 0.0759 0.0759
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Leishmania major hypothetical protein, conserved 0.0265 0.0591 0.0502
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.023 0.0465 0.0421
Echinococcus granulosus mitogen activated protein kinase 3 0.0162 0.0221 0.0221
Echinococcus granulosus cGMP dependent protein kinase 0.0162 0.0222 0.0222
Onchocerca volvulus 0.0126 0.0092 0.027
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0195 0.034 0.0295
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0263 0.0586 0.0542
Schistosoma mansoni serine/threonine-protein kinase 0.0317 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0216 0.0415 0.0409
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0317 0.078 0.078
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0195 0.034 0.0334
Loa Loa (eye worm) TK protein kinase 0.0487 0.1392 0.1386
Brugia malayi hypothetical protein 0.0163 0.0224 0.0206
Brugia malayi p70 ribosomal S6 kinase beta 0.055 0.1619 0.1603
Brugia malayi SRC-1 0.0294 0.0698 0.068
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) projectin 0.0154 0.0194 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0265 0.0591 0.1596
Echinococcus granulosus Immunoglobulin subtype 0.0163 0.0224 0.0224
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0269 0.0606 0.0599
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0326 0.0813 0.0813
Echinococcus granulosus protein jagged 2 0.0291 0.0685 0.0685
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0163 0.0224 0.0224
Brugia malayi ephrin receptor 1 precursor 0.0121 0.0073 0.0055
Loa Loa (eye worm) disorganized muscle protein 1 0.0137 0.0131 0.0124
Brugia malayi protein-tyrosine kinase 0.024 0.0501 0.0483
Brugia malayi Serotonin receptor 0.0602 0.1807 0.1791
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0195 0.034 0.0295
Brugia malayi Cyclin C 0.1709 0.5793 0.5785
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0195 0.034 0.034
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0164 0.0228 0.0209
Echinococcus granulosus titin 0.0137 0.0131 0.0131
Brugia malayi Protein kinase domain containing protein 0.0565 0.1672 0.1656
Loa Loa (eye worm) SRC-1 0.0294 0.0698 0.0691
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0265 0.0591 0.1812
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Giardia lamblia Kinase, STE STE20 0.0164 0.0228 0.0438
Onchocerca volvulus 0.0124 0.0083 0.0235
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus multilocularis mitogen activated protein kinase 11 0.0308 0.0746 0.0746
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0997 0.3229 0.3197
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0127 0.0096 0.0077
Onchocerca volvulus 0.0174 0.0263 0.0953
Echinococcus multilocularis tyrosine protein kinase HCK 0.0176 0.0272 0.0272
Echinococcus multilocularis cyclin dependent kinase 1 0.023 0.0465 0.0465
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Echinococcus multilocularis glutamate synthase 0.0265 0.0591 0.0591
Trichomonas vaginalis mercuric reductase, putative 0.0997 0.3229 1
Entamoeba histolytica protein kinase, putative 0.055 0.1619 0.5865
Trichomonas vaginalis STE family protein kinase 0.0263 0.0586 0.1797
Brugia malayi Thioredoxin reductase 0.2877 1 1
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Onchocerca volvulus 0.0291 0.0685 0.2636
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0997 0.3229 0.3197
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0164 0.0228 0.0209
Echinococcus multilocularis fat cadherin tumor suppressor 0.0291 0.0685 0.0685
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0269 0.0606 0.0588
Brugia malayi P38 map kinase family protein 2 0.0308 0.0746 0.0728
Schistosoma mansoni slit 0.0291 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.0827 0.2618 0.2613
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.043 0.1185 0.1179
Brugia malayi protein kinase C3,putative 0.0305 0.0736 0.0718
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.0287 0.0269
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0106 0.0019 0.0012
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Echinococcus multilocularis C type lectin domian containing protein 0.0537 0.1571 0.1571
Brugia malayi serine/threonine protein kinase 6 0.0227 0.0456 0.0438
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0265 0.0591 0.0547
Giardia lamblia Kinase, CMGC CLK 0.0297 0.0708 0.1968
Loa Loa (eye worm) hypothetical protein 0.0195 0.034 0.0334
Trypanosoma cruzi cdc2-related kinase 1 0.023 0.0465 0.0447
Schistosoma mansoni hypothetical protein 0.0216 0.0415 0.0415
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0308 0.0746 0.0659
Onchocerca volvulus 0.0537 0.1571 0.6174
Plasmodium vivax serine/threonine protein kinase, putative 0.0161 0.0217 0.0171
Echinococcus multilocularis dual specificity 0.0236 0.0489 0.0489
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0265 0.0591 0.1711
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Plasmodium vivax calcium-dependent protein kinase, putative 0.0195 0.034 0.0295
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Onchocerca volvulus 0.0154 0.0194 0.0676
Schistosoma mansoni netrin receptor unc5 0.0219 0.0425 0.0425
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0227 0.0456 0.165
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0267 0.06 0.184
Brugia malayi Kinase associated domain 1 family protein 0.0197 0.0347 0.0329
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Echinococcus multilocularis raf serine:threonine protein kinase 0.0143 0.0154 0.0154
Brugia malayi Protein kinase domain containing protein 0.012 0.0069 0.005
Echinococcus multilocularis tyrosine protein kinase Srms 0.024 0.0501 0.0501
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0317 0.078 0.0774
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0265 0.0591 0.0502
Schistosoma mansoni tyrosine kinase 0.0269 0.0608 0.0608
Schistosoma mansoni purine nucleoside phosphorylase 0.0126 0.009 0.009
Schistosoma mansoni protein kinase 0.0512 0.1482 0.1482
Loa Loa (eye worm) CAMK protein kinase 0.0218 0.0424 0.0417
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0222 0.0222
Entamoeba histolytica hypothetical protein 0.0236 0.0489 0.1772
Echinococcus granulosus ephrin type A receptor 4 A 0.0186 0.0309 0.0309
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.028 0.0646 0.0646
Schistosoma mansoni septate junction protein 0.03 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0268 0.0604 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0456 0.0456
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0127 0.0096 0.0077
Plasmodium falciparum protein serine/threonine kinase-1 0.0297 0.0708 0.0664
Echinococcus multilocularis cyclin dependent kinase 9 0.0156 0.0198 0.0198
Schistosoma mansoni serine/threonine protein kinase 0.0474 0.1344 0.1344
Entamoeba histolytica protein kinase domain containing protein 0.0269 0.0606 0.2194
Loa Loa (eye worm) hypothetical protein 0.0334 0.0839 0.0833
Echinococcus multilocularis dual specificity 0.0269 0.0606 0.0606
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0392 0.1049 0.1042
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0454 0.1274 0.1274
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0219 0.0425 0.0381
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis expressed conserved protein 0.0162 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trypanosoma brucei aurora B kinase 0.0227 0.0456 0.0366
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0392 0.1049 0.1032
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.018 0.0287 0.028
Schistosoma mansoni atypical protein kinase C 0.0564 0.1669 0.1669
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0151 0.0182 0.0182
Toxoplasma gondii AGC kinase 0.0219 0.0425 0.0381
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0223 0.0439 0.0439
Echinococcus multilocularis 0.0137 0.0131 0.0131
Echinococcus granulosus protein jagged 1 0.0291 0.0685 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0424 0.0424
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Schistosoma mansoni tyrosine kinase 0.0402 0.1087 0.1087
Giardia lamblia Kinase, AGC PKA 0.0219 0.0425 0.1067
Leishmania major casein kinase II, putative 0.0194 0.0335 0.0244
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0241 0.0504 0.046
Loa Loa (eye worm) hypothetical protein 0.0371 0.0976 0.0969
Echinococcus granulosus casein kinase I alpha 0.021 0.0395 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Echinococcus granulosus neurogenic locus notch protein 4 0.0291 0.0685 0.0685
Onchocerca volvulus Peroxidasin homolog 0.0137 0.0131 0.0425
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0265 0.0591 0.0591
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Echinococcus granulosus c-Jun N-terminal kinases 0.0511 0.1478 0.1478
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0297 0.0708 0.0664
Schistosoma mansoni laminin gamma-3 chain 0.0291 0.0685 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0361 0.0361
Echinococcus granulosus tyrosine protein kinase Src42A 0.0179 0.0282 0.0282
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0297 0.0708 0.069
Trichomonas vaginalis apoptosis inducing factor, putative 0.0265 0.0591 0.1812
Echinococcus granulosus cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Brugia malayi Hr1 repeat family protein 0.0562 0.1661 0.1645
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0137 0.0131 0.0131
Echinococcus granulosus cyclin dependent kinase 9 0.0172 0.0256 0.0256
Entamoeba histolytica protein kinase , putative 0.0227 0.0456 0.165
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0303 0.0728 0.0728
Entamoeba histolytica protein kinase, putative 0.0197 0.0349 0.1264
Echinococcus granulosus contactin 0.0317 0.078 0.078
Trichomonas vaginalis AGC family protein kinase 0.0346 0.0883 0.2718
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3165
Echinococcus granulosus tyrosine protein kinase ABL1 0.0126 0.0092 0.0092
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Plasmodium falciparum calcium-dependent protein kinase 2 0.0195 0.034 0.0295
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0511 0.1478 0.1478
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0157 0.0204 0.0185
Schistosoma mansoni protein kinase 0.0124 0.0086 0.0086
Toxoplasma gondii NADPH-glutathione reductase 0.0997 0.3229 0.3197
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Brugia malayi basement membrane proteoglycan precursor 0.0163 0.0224 0.0206
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0227 0.0456 0.0456
Brugia malayi Disorganized muscle protein 1 0.0137 0.0131 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0311 0.0759 0.0759
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0292 0.0688 0.0682
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0997 0.3229 0.3197
Brugia malayi Calcium binding EGF domain containing protein 0.0291 0.0685 0.0667
Loa Loa (eye worm) hypothetical protein 0.084 0.2664 0.2659
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0284 0.0662 0.2034
Entamoeba histolytica protein kinase, putative 0.0161 0.0217 0.0785
Brugia malayi Protein kinase domain containing protein 0.0613 0.1846 0.183
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0265 0.0591 0.0591
Trichomonas vaginalis CAMK family protein kinase 0.0419 0.1148 0.3543
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0265 0.0591 0.0547
Loa Loa (eye worm) hypothetical protein 0.0357 0.0925 0.0918
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Brugia malayi Fes/CIP4 homology domain containing protein 0.0197 0.0349 0.0331
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0162 0.0222 0.0177
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Brugia malayi SH2 domain containing protein 0.042 0.115 0.1134
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0127 0.0097 0.035
Onchocerca volvulus 0.0537 0.1571 0.6174
Leishmania major protein kinase, putative 0.0164 0.0228 0.0135
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0263 0.0795
Brugia malayi casein kinase I 0.021 0.0395 0.0377
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Echinococcus granulosus insulin growth factor binding 0.0137 0.0131 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0198 0.0198
Mycobacterium ulcerans ferredoxin reductase 0.0265 0.0591 0.1711
Echinococcus granulosus expressed protein 0.0161 0.0217 0.0217
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0395 0.1203
Onchocerca volvulus Serine\/threonine kinase homolog 0.0522 0.1519 0.5967
Plasmodium falciparum calcium-dependent protein kinase 4 0.0195 0.034 0.0295
Loa Loa (eye worm) hypothetical protein 0.0357 0.0925 0.0918
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0703 0.2171 0.2171
Schistosoma mansoni hypothetical protein 0.0197 0.0347 0.0347
Schistosoma mansoni serine/threonine kinase 0.0436 0.1206 0.1206
Trypanosoma cruzi Protein kinase B 0.0317 0.0781 0.0764
Plasmodium falciparum casein kinase 1 0.021 0.0395 0.035
Brugia malayi cell division control protein 2 homolog 0.023 0.0465 0.0447
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0265 0.0591 0.0547
Leishmania major hypothetical protein, conserved 0.0265 0.0591 0.0502
Giardia lamblia Kinase, CMGC DYRK 0.0269 0.0606 0.1643
Echinococcus multilocularis fibroblast growth factor receptor 4 0.035 0.0899 0.0899
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi hypothetical protein 0.043 0.1185 0.1168
Echinococcus multilocularis titin 0.0137 0.0131 0.0131
Echinococcus multilocularis rho associated protein kinase 0.0628 0.1901 0.1901
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0144 0.0157 0.0151
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0291 0.0685 0.2636
Trichomonas vaginalis STE family protein kinase 0.0124 0.0086 0.0246
Loa Loa (eye worm) hypothetical protein 0.0276 0.0632 0.0625
Entamoeba histolytica PH domain containing protein kinase, putative 0.0317 0.0781 0.2829
Entamoeba histolytica protein kinase, putative 0.0236 0.0489 0.1772
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0681 0.2092 0.2077
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0303 0.0728 0.0728
Loa Loa (eye worm) AGC/AKT protein kinase 0.0565 0.1672 0.1666
Schistosoma mansoni protein kinase 0.0296 0.0704 0.0704
Loa Loa (eye worm) TK/EGFR protein kinase 0.0667 0.2038 0.2033
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.1519 0.1519
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0297 0.0708 0.069
Echinococcus multilocularis epidermal growth factor receptor 0.0465 0.1312 0.1312
Loa Loa (eye worm) hypothetical protein 0.0708 0.2188 0.2182
Entamoeba histolytica cell division protein kinase 2, putative 0.023 0.0465 0.1685
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Schistosoma mansoni tyrosine kinase 0.035 0.0899 0.0899
Brugia malayi Protein kinase domain containing protein 0.0161 0.0217 0.0198
Echinococcus granulosus rho-associated protein kinase 1 0.0628 0.1901 0.1901
Echinococcus multilocularis growth factor receptor bound protein 2 0.0118 0.0064 0.0064
Echinococcus granulosus nephrin 0.0154 0.0194 0.0194
Echinococcus granulosus Down syndrome cell adhesion molecule 0.018 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0541 0.1585 0.1579
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0118 0.0064 0.0057
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0179 0.0282 0.0282
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Brugia malayi Peroxidasin 0.03 0.0719 0.0701
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.1122 0.1122
Echinococcus granulosus notch 0.0291 0.0685 0.0685
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0164 0.0228 0.0135
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0317 0.0778 0.0772
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus granulosus casein kinase I alpha 0.021 0.0395 0.0395
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0126 0.009 0.0262
Echinococcus granulosus roundabout 2 0.0317 0.078 0.078
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.024 0.0501 0.0501
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0613 0.1846 0.184
Entamoeba histolytica protein kinase, putative 0.0311 0.0759 0.2747
Echinococcus multilocularis titin 0.0137 0.0131 0.0131
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0227 0.0456 0.0411
Plasmodium vivax thioredoxin reductase, putative 0.2877 1 1
Onchocerca volvulus 0.0357 0.0923 0.3586
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0265 0.0591 0.1711
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Leishmania major protein kinase A catalytic subunit 0.0219 0.0425 0.0335
Trypanosoma brucei SNF1-related protein kinases, putative 0.0151 0.0182 0.009
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0146 0.0165 0.0146
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Schistosoma mansoni protein kinase 0.0839 0.2658 0.2658
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0157 0.0157
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0127 0.0093 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0162 0.0221 0.0129
Brugia malayi Delta serrate ligand family protein 0.0291 0.0685 0.0667
Trichomonas vaginalis AGC family protein kinase 0.0158 0.0205 0.0616
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0265 0.0591 0.0547
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Echinococcus multilocularis roundabout 2 0.0317 0.078 0.078
Echinococcus granulosus calcium activated potassium channel 0.0261 0.0577 0.0577
Echinococcus multilocularis twitchin 0.0201 0.0361 0.0361
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0395 0.1203
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0137 0.0131 0.0112
Schistosoma mansoni basigin related 0.0163 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0233 0.0478 0.0471
Onchocerca volvulus 0.0137 0.0131 0.0425
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Toxoplasma gondii EGF family domain-containing protein 0.0291 0.0685 0.0641
Echinococcus multilocularis 0.0185 0.0303 0.0303
Entamoeba histolytica casein kinase 1, putative 0.021 0.0395 0.1429
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0265 0.0591 0.0591
Leishmania major protein kinase, putative 0.0195 0.034 0.0249
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0294 0.0698 0.0698
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.03 0.0717 0.0717
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0415 0.0415
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0249 0.0534 0.0527
Loa Loa (eye worm) hypothetical protein 0.0445 0.124 0.1234
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0194 0.0187
Trichomonas vaginalis CAMK family protein kinase 0.0539 0.1577 0.4874
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3229
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0137 0.0131 0.0131
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0227 0.0456 0.0456
Plasmodium vivax unspecified product 0.0194 0.0335 0.029
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.034 0.034
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0236 0.0489 0.0471
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0502
Echinococcus granulosus mitogen activated protein kinase 0.0162 0.0221 0.0221
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0194 0.0335 0.029
Echinococcus granulosus delta-like protein 1 0.0291 0.0685 0.0685
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Entamoeba histolytica protein kinase, putative 0.0139 0.0139 0.0503
Echinococcus multilocularis nervana 2 0.0239 0.0498 0.0498
Echinococcus granulosus mitogen activated protein kinase 11 0.0308 0.0746 0.0746
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0596 0.1784 0.1784
Trichomonas vaginalis AGC family protein kinase 0.0331 0.083 0.2554
Echinococcus multilocularis N chimaerin 0.0144 0.0157 0.0157
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0361 0.0937 0.0937
Echinococcus multilocularis calcium dependent protein kinase 0.0131 0.011 0.011
Echinococcus granulosus growth factor receptor bound protein 2 0.012 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0395 0.0395
Echinococcus multilocularis protein jagged 1 0.0291 0.0685 0.0685
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0219 0.0425 0.0381
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Schistosoma mansoni nephrin related 0.0137 0.0131 0.0131
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0265 0.0591 0.0573
Plasmodium falciparum glutathione reductase 0.2877 1 1
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0502
Echinococcus granulosus tyrosine protein kinase HCK 0.0176 0.0272 0.0272
Brugia malayi intracellular kinase 0.0249 0.0534 0.0516
Entamoeba histolytica protein kinase, putative 0.0139 0.0139 0.0503
Brugia malayi Protein kinase domain containing protein 0.023 0.0465 0.0447
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0265 0.0591 0.0573
Onchocerca volvulus Basement membrane proteoglycan homolog 0.03 0.0717 0.2765
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0106 0.0019 0.0037
Echinococcus granulosus lachesin 0.03 0.0717 0.0717
Schistosoma mansoni serine/threonine protein kinase 0.0493 0.1413 0.1413
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0219 0.0425 0.0335
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0681 0.2092 0.2087
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0161 0.0217 0.0171
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0439 0.122 0.122
Plasmodium falciparum thioredoxin reductase 0.0997 0.3229 0.3197
Echinococcus granulosus protein jagged 2 0.0291 0.0685 0.0685
Entamoeba histolytica casein kinase, putative 0.021 0.0395 0.1429
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0195 0.034 0.0295
Echinococcus multilocularis NCK adaptor protein 0.012 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus granulosus NCK adaptor protein 0.0118 0.0064 0.0064
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0195 0.034 0.0295
Echinococcus granulosus tyrosine protein kinase Lyn 0.0358 0.0928 0.0928
Brugia malayi Immunoglobulin I-set domain containing protein 0.0487 0.1392 0.1376
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0522 0.1519 0.1519
Schistosoma mansoni protein kinase 0.0839 0.2658 0.2658
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus multilocularis roundabout 2 0.0858 0.2727 0.2727
Echinococcus granulosus tyrosine protein kinase Blk 0.024 0.0501 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.1049 0.1049
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0427 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Loa Loa (eye worm) hypothetical protein 0.023 0.0466 0.0459
Echinococcus granulosus netrin receptor unc 5 0.0219 0.0425 0.0425
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0317 0.0781 0.0764
Echinococcus granulosus titin 0.0137 0.0131 0.0131
Loa Loa (eye worm) programmed cell death 8 0.0265 0.0591 0.0584
Echinococcus granulosus c src tyrosine kinase 0.0181 0.0289 0.0289
Giardia lamblia Kinase, CK1 Casein kinase 0.021 0.0395 0.0971
Schistosoma mansoni tyrosine kinase 0.0294 0.0698 0.0698
Trypanosoma brucei rac serine-threonine kinase, putative 0.0565 0.1672 0.1593
Echinococcus multilocularis neuroglian 0.0317 0.078 0.078
Echinococcus multilocularis thioredoxin glutathione reductase 0.2877 1 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.021 0.0395 0.0388
Echinococcus granulosus fibropellin Ia 0.0291 0.0685 0.0685
Brugia malayi Tyrosine-protein kinase abl-1 0.0181 0.0289 0.0271
Echinococcus granulosus casein kinase I alpha 0.021 0.0395 0.0395
Brugia malayi Protein kinase domain containing protein 0.0388 0.1036 0.1019
Brugia malayi Protein kinase c protein 2 0.0224 0.0444 0.0426
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Giardia lamblia Kinase, AGC PKA 0.0303 0.0728 0.2034
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0265 0.0591 0.1711
Schistosoma mansoni basigin related 0.0163 0.0224 0.0224
Schistosoma mansoni tyrosine kinase 0.0578 0.1721 0.1721
Loa Loa (eye worm) hypothetical protein 0.0124 0.0083 0.0076
Schistosoma mansoni cell polarity protein 0.0291 0.0685 0.0685
Schistosoma mansoni tyrosine kinase 0.0333 0.0837 0.0837
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Trypanosoma cruzi cdc2-related kinase 3 0.023 0.0465 0.0447
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Brugia malayi Protein kinase domain containing protein 0.0297 0.0708 0.069
Plasmodium falciparum serine/threonine protein kinase 0.0161 0.0217 0.0171
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Onchocerca volvulus 0.0537 0.1571 0.6174
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0219 0.0425 0.0407
Echinococcus granulosus serine:threonine protein kinase 3 0.0496 0.1426 0.1426
Brugia malayi Doublecortin family protein 0.0292 0.0688 0.0671
Giardia lamblia Kinase, CDC7 0.0174 0.0263 0.0552
Echinococcus multilocularis casein kinase I gamma 0.0412 0.1122 0.1122
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0681 0.2092 0.2092
Schistosoma mansoni serine/threonine protein kinase 0.0762 0.2382 0.2382
Loa Loa (eye worm) hypothetical protein 0.0268 0.0604 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0708 0.0708
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.182 0.6194 0.6191
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0126 0.009 0.0044
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0127 0.0093 0.0075
Trichomonas vaginalis AGC family protein kinase 0.0219 0.0425 0.1298
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0151 0.0182 0.009
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0439 0.122 0.122
Entamoeba histolytica serine/threonine protein kinase, putative 0.0151 0.0182 0.066
Trypanosoma cruzi trypanothione reductase, putative 0.2877 1 1
Loa Loa (eye worm) hypothetical protein 0.0151 0.0182 0.0175
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0224 0.0206
Loa Loa (eye worm) hypothetical protein 0.0276 0.0632 0.0625
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0162 0.0221 0.0214
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Entamoeba histolytica protein kinase, putative 0.0565 0.1672 0.6055
Brugia malayi Immunoglobulin I-set domain containing protein 0.1369 0.457 0.456
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0127 0.0093 0.0075
Schistosoma mansoni glutamate synthase 0.0265 0.0591 0.0591
Brugia malayi Calcium binding EGF domain containing protein 0.0291 0.0685 0.0667
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0709 0.2191 0.2191
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0163 0.0224 0.0217
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0265 0.0591 0.0502
Loa Loa (eye worm) hypothetical protein 0.0219 0.0425 0.0418
Entamoeba histolytica p21-activated kinase 0.0181 0.029 0.1049
Plasmodium falciparum thioredoxin reductase 0.2877 1 1
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0865 0.2754 0.2754
Schistosoma mansoni sulfide quinone reductase 0.0265 0.0591 0.0591
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0541 0.1585 0.1585
Echinococcus granulosus defective proboscis extension response 0.0541 0.1585 0.1585
Echinococcus granulosus down syndrome cell adhesion 0.0137 0.0131 0.0131
Echinococcus multilocularis protein kinase c epsilon type 0.0394 0.1058 0.1058
Echinococcus multilocularis Immunoglobulin 0.0541 0.1585 0.1585
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Entamoeba histolytica protein kinase, putative 0.0158 0.0205 0.0744
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Schistosoma mansoni glutamate synthase 0.0265 0.0591 0.0591
Echinococcus multilocularis CDC7 cell division cycle 7 0.0174 0.0263 0.0263
Entamoeba histolytica protein kinase, putative 0.0124 0.0086 0.0312
Echinococcus granulosus dual specificity 0.0269 0.0606 0.0606
Schistosoma mansoni vav2 0.0159 0.021 0.021
Onchocerca volvulus 0.0137 0.0131 0.0425
Giardia lamblia Kinase, NEK 0.0263 0.0586 0.158
Onchocerca volvulus Netrin receptor homolog 0.0193 0.0332 0.1228
Schistosoma mansoni serine/threonine protein kinase 0.1146 0.3764 0.3764
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0226 0.0207
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Entamoeba histolytica protein kinase domain containing protein 0.0249 0.0534 0.1934
Entamoeba histolytica disulphide oxidoreductase, putative 0.0265 0.0591 0.214
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0151 0.0182 0.009
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0613 0.1846 0.184
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Plasmodium falciparum NIMA related kinase 1 0.0263 0.0586 0.0542
Plasmodium falciparum serine/threonine protein kinase KIN 0.0151 0.0182 0.0137
Echinococcus granulosus protein kinase 0.0296 0.0704 0.0704
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus multilocularis myosin iiia 0.0164 0.0228 0.0228
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0151 0.0182 0.0164
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0163 0.0224 0.0224
Echinococcus granulosus N chimaerin 0.0144 0.0157 0.0157
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Schistosoma mansoni tyrosine kinase 0.0294 0.0698 0.0698
Giardia lamblia Kinase, CAMK CAMKL 0.0167 0.024 0.0478
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0265 0.0591 0.0547
Toxoplasma gondii aurora kinase 0.0227 0.0456 0.0411
Echinococcus multilocularis netrin receptor unc 5 0.0219 0.0425 0.0425
Echinococcus multilocularis mitogen activated protein kinase 14 0.0308 0.0746 0.0746
Onchocerca volvulus 0.0126 0.0092 0.027
Mycobacterium ulcerans glutamate synthase subunit beta 0.0265 0.0591 0.1711
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Echinococcus granulosus twitchin 0.0741 0.2308 0.2308
Echinococcus multilocularis titin 0.0218 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0703 0.2171 0.2166
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.0662 0.2034
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0997 0.3229 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) AGC/PKA protein kinase 0.0219 0.0425 0.0418
Entamoeba histolytica protein kinase domain containing protein 0.0392 0.1049 0.3798
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0166 0.0237 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0217 0.0217
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0522 0.1519 0.1439
Echinococcus granulosus tyrosine protein kinase otk 0.03 0.0717 0.0717
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0265 0.0591 0.1711
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0216 0.0415 0.0415
Entamoeba histolytica PH domain containing protein kinase, putative 0.0317 0.0781 0.2829
Entamoeba histolytica protein kinase domain containing protein 0.0227 0.0456 0.165
Trypanosoma brucei hypothetical protein, conserved 0.0265 0.0591 0.0502
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0644 0.1956 0.195
Echinococcus granulosus activin receptor type 0.0127 0.0093 0.0093
Plasmodium vivax protein kinase Crk2 0.023 0.0465 0.0421
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0577 0.0577
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0239 0.0498 0.0498
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0171 0.0254 0.0765
Echinococcus granulosus neural cadherin 0.0291 0.0685 0.0685
Trypanosoma cruzi trypanothione reductase, putative 0.0997 0.3229 0.3216
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1478 0.1478
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0265 0.0591 0.0591
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Echinococcus multilocularis hemicentin 1 0.03 0.0717 0.0717
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0227 0.0456 0.165
Echinococcus granulosus Vam6:Vps39 protein 0.0216 0.0415 0.0415
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0534 0.1636
Echinococcus granulosus nervana 2 0.0239 0.0498 0.0498
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0448 0.1252 0.1252
Echinococcus multilocularis insulin growth factor binding 0.0137 0.0131 0.0131
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.035 0.0899 0.0899
Schistosoma mansoni hemicentin 0.0154 0.0194 0.0194
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0297 0.0708 0.069
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Plasmodium falciparum calcium-dependent protein kinase 1 0.0195 0.034 0.0295
Brugia malayi Protein kinase domain containing protein 0.0317 0.078 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.078 0.078
Echinococcus granulosus peroxidasin 0.03 0.0719 0.0719
Brugia malayi probable protein kinase 0.0512 0.1482 0.1466
Entamoeba histolytica protein kinase, putative 0.0565 0.1672 0.6055
Echinococcus multilocularis fibropellin Ia 0.0291 0.0685 0.0685
Schistosoma mansoni vesicular amine transporter 0.0541 0.1585 0.1585
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0265 0.0591 0.1711
Onchocerca volvulus Putative titin 0.0137 0.0131 0.0425
Onchocerca volvulus 0.0291 0.0685 0.2636
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3165
Onchocerca volvulus 0.0174 0.0263 0.0953
Schistosoma mansoni septate junction protein 0.0291 0.0685 0.0685
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Trypanosoma cruzi casein kinase, delta isoform, putative 0.021 0.0395 0.0377
Schistosoma mansoni tyrosine kinase 0.0465 0.1312 0.1312
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0163 0.0224 0.0224
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Echinococcus multilocularis c4b binding protein beta chain 0.0537 0.1571 0.1571
Echinococcus multilocularis protein kinase shaggy 0.0249 0.0534 0.0534
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0161 0.0217 0.021
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0269 0.0606 0.0517
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus multilocularis insulin receptor 0.0578 0.1721 0.1721
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0308 0.0746 0.0728
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0454 0.1274 0.1274
Leishmania major hypothetical protein, conserved 0.0127 0.0096 0.0003
Echinococcus granulosus calcium dependent protein kinase 0.0131 0.011 0.011
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0265 0.0591 0.1711
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0997 0.3229 0.3165
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0161 0.0217 0.0125
Entamoeba histolytica hypothetical protein 0.0368 0.0963 0.349
Echinococcus granulosus thioredoxin glutathione reductase 0.2877 1 1
Loa Loa (eye worm) hypothetical protein 0.0821 0.2596 0.2591
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0195 0.034 0.0249
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0157 0.0202 0.0157
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0265 0.0591 0.0591
Mycobacterium ulcerans monoxygenase 0.0265 0.0591 0.1711
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0425 0.0425
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0157 0.0204 0.0204
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.0518 0.1586
Schistosoma mansoni tyrosine kinase 0.0553 0.1629 0.1629
Brugia malayi Prion-like- 0.03 0.0717 0.07
Onchocerca volvulus 0.0537 0.1571 0.6174
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0415 0.0397
Echinococcus granulosus tyrosine protein kinase 0.0295 0.07 0.07
Toxoplasma gondii casein kinase I 0.021 0.0395 0.035
Brugia malayi Variant SH3 domain containing protein 0.0144 0.0157 0.0139
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0265 0.0591 0.0591
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0249 0.0534 0.0527
Entamoeba histolytica protein kinase, putative 0.0127 0.0097 0.035
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0335 0.1214
Schistosoma mansoni purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0162 0.0221 0.0221
Schistosoma mansoni hypothetical protein 0.0197 0.0347 0.0347
Schistosoma mansoni nephrin 0.0317 0.078 0.078
Giardia lamblia Kinase, CAMK CAMKL 0.0167 0.024 0.0478
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0265 0.0591 0.0502
Brugia malayi Cadherin domain containing protein 0.0291 0.0685 0.0667
Schistosoma mansoni netrin receptor unc5 0.0163 0.0224 0.0224
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1146 0.3764 0.376
Brugia malayi serine/threonine-protein kinase plk-2 0.0522 0.1519 0.1503
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0394 0.1058 0.1052
Brugia malayi Protein kinase domain containing protein 0.0373 0.098 0.0963
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0157 0.0204 0.0112
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0317 0.078 0.0774
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0118 0.0064 0.0057
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi Protein kinase domain containing protein 0.0292 0.0689 0.0671
Echinococcus multilocularis serine threonine protein kinase 0.039 0.1043 0.1043
Trypanosoma cruzi cdc2-related kinase 3 0.023 0.0465 0.0447
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0265 0.0591 0.1812
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0644 0.1956 0.1941
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Schistosoma mansoni cell adhesion molecule 0.0154 0.0194 0.0194
Echinococcus granulosus tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Schistosoma mansoni cell adhesion molecule 0.0137 0.0131 0.0131
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0245 0.0519 0.0519
Schistosoma mansoni growth factor receptor-bound protein 0.012 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.1058 0.1058
Loa Loa (eye worm) hypothetical protein 0.03 0.0719 0.0712
Echinococcus granulosus tyrosine protein kinase Src42A 0.0294 0.0698 0.0698
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0317 0.078 0.078
Giardia lamblia Kinase, STE STE20 0.0166 0.0237 0.0468
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0681 0.2092 0.8254
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0997 0.3229 0.3216
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0245 0.0519 0.0501
Echinococcus multilocularis aurora kinase A 0.0227 0.0456 0.0456
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0265 0.0591 0.0584
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Leishmania major protein kinase, putative 0.0297 0.0708 0.062
Loa Loa (eye worm) AUR protein kinase 0.0227 0.0456 0.0449
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Loa Loa (eye worm) cyclin domain-containing protein 0.0855 0.2717 0.2712
Entamoeba histolytica protein kinase domain containing protein 0.0249 0.0534 0.1934
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Echinococcus granulosus serine:threonine kinase SAD 1 0.0151 0.0182 0.0182
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0163 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0216 0.0415 0.0409
Echinococcus granulosus dual specificity 0.0236 0.0489 0.0489
Brugia malayi phosphoinositide-dependent protein kinase I 0.0158 0.0205 0.0187
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0162 0.0221 0.0203
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0194 0.0335 0.0328
Echinococcus multilocularis Immunoglobulin subtype 0.0163 0.0224 0.0224
Brugia malayi serine/threonine-protein kinase PAK 7 0.0449 0.1254 0.1237
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2877 1 1
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0219 0.0425 0.0381
Echinococcus granulosus neurogenic locus protein delta 0.0291 0.0685 0.0685
Onchocerca volvulus Tyrosine kinase homolog 0.0803 0.253 1
Plasmodium falciparum protein kinase 5 0.023 0.0465 0.0421
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0249 0.0534 0.049
Entamoeba histolytica protein kinase, putative 0.0227 0.0456 0.165
Echinococcus granulosus serine/threonine protein kinase 0.0317 0.0781 0.0781
Loa Loa (eye worm) hypothetical protein 0.0349 0.0895 0.0888
Echinococcus granulosus tyrosine kinase 0.024 0.0501 0.0501
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Echinococcus granulosus hypothetical protein 0.0233 0.0478 0.0478
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0263 0.0795
Entamoeba histolytica protein kinase, putative 0.0166 0.0237 0.0859
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0265 0.0591 0.0547
Brugia malayi Protein kinase domain containing protein 0.0613 0.1846 0.183
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0496 0.1426 0.142
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0265 0.0591 0.214
Schistosoma mansoni titin 0.0218 0.0424 0.0424
Echinococcus multilocularis neuroglian 0.0678 0.2078 0.2078
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0263 0.0586 0.0542
Loa Loa (eye worm) hypothetical protein 0.0541 0.1587 0.1581
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0151 0.0182 0.009
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0326 0.0813 0.0813
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.021 0.0395 0.0388
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0249 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0613 0.1846 0.184
Brugia malayi Protein kinase domain containing protein 0.0295 0.07 0.0682
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0263 0.0795
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0855 0.2717 0.2717
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0265 0.0591 0.214
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Brugia malayi Protein kinase domain containing protein 0.1146 0.3764 0.3753
Loa Loa (eye worm) hypothetical protein 0.0221 0.0433 0.0426
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Brugia malayi Calcium binding EGF domain containing protein 0.0291 0.0685 0.0667
Trichomonas vaginalis glutamate synthase, putative 0.0265 0.0591 0.1812
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0839 0.2658 0.2658
Schistosoma mansoni tyrosine kinase 0.0181 0.0289 0.0289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0562 0.1661 0.1661
Echinococcus multilocularis PAK box P21 Rho binding 0.0124 0.0086 0.0086
Schistosoma mansoni septate junction protein 0.0163 0.0224 0.0224
Schistosoma mansoni protein kinase 0.021 0.0395 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0519 0.0519
Echinococcus multilocularis lachesin 0.03 0.0717 0.0717
Echinococcus granulosus dual specificity protein kinase clk2 0.0297 0.0708 0.0708
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0997 0.3229 0.3197
Giardia lamblia Kinase, CMGC CDK 0.023 0.0465 0.1196
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Brugia malayi Stress-activated protein kinase jnk-1 0.0511 0.1478 0.1462
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0154 0.0154
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0166 0.0237 0.0237
Echinococcus multilocularis transfer RNA-Phe 0.0154 0.0194 0.0194
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0997 0.3229 0.3165
Brugia malayi Immunoglobulin I-set domain containing protein 0.0558 0.1648 0.1632
Schistosoma mansoni ste20-related kinase 0.0397 0.1066 0.1066
Loa Loa (eye worm) glutathione reductase 0.2877 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.043 0.1185 0.1185
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0265 0.0591 0.214
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0219 0.0425 0.0407
Echinococcus granulosus epidermal growth factor receptor 0.0465 0.1312 0.1312
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0163 0.0224 0.0224
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Loa Loa (eye worm) TK/ABL protein kinase 0.0126 0.0092 0.0085
Onchocerca volvulus Putative cubilin 0.0291 0.0685 0.2636
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0137 0.0133 0.0133
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0126 0.009 0.0258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.0433 0.0433
Brugia malayi Variant SH3 domain containing protein 0.0118 0.0064 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Echinococcus multilocularis dual specificity protein kinase clk2 0.0297 0.0708 0.0708
Echinococcus multilocularis roundabout 2 0.0317 0.078 0.078
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0474 0.1344 0.1344
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0573
Loa Loa (eye worm) TK/ALK protein kinase 0.0292 0.0688 0.0682
Echinococcus granulosus Glutaredoxin protein 5 0.0239 0.0498 0.0498
Schistosoma mansoni cell adhesion molecule 0.0317 0.078 0.078
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0144 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Brugia malayi Immunoglobulin domain containing protein 0.0163 0.0224 0.0206
Schistosoma mansoni cell adhesion molecule 0.0317 0.078 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Trypanosoma brucei protein kinase, putative 0.0178 0.0279 0.0187
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0093 0.0338
Entamoeba histolytica thioredoxin reductase, putative 0.0265 0.0591 0.214
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.0489 0.1772
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0224 0.0206
Brugia malayi protein kinase C II. 0.0394 0.1058 0.1042
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0195 0.034 0.0334
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Trypanosoma brucei cdc2-related kinase 1 0.023 0.0465 0.0375
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0265 0.0591 0.1711
Plasmodium falciparum glutathione reductase 0.0997 0.3229 0.3197
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Echinococcus multilocularis protein jagged 2 0.0291 0.0685 0.0685
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.0433 0.1321
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0449 0.1254 0.1248
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Echinococcus multilocularis notch 0.0291 0.0685 0.0685
Brugia malayi hypothetical protein 0.0126 0.0092 0.0073
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0195 0.034 0.0295
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus roundabout 2 0.0317 0.078 0.078
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0681 0.2092 0.2092
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0955 0.3079 0.3079
Echinococcus multilocularis titin 0.0137 0.0131 0.0131
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0997 0.3229 1
Trichomonas vaginalis AGC family protein kinase 0.0331 0.083 0.2554
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Loa Loa (eye worm) Notch2 0.0291 0.0685 0.0678
Brugia malayi Prion-like- 0.0137 0.0131 0.0112
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.1142 0.1142
Mycobacterium tuberculosis Probable oxidoreductase 0.0997 0.3229 0.3197
Echinococcus multilocularis peroxidasin 0.03 0.0719 0.0719
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0855 0.2717 0.2717
Brugia malayi Protein kinase domain containing protein 0.0419 0.1148 0.1132
Onchocerca volvulus 0.0146 0.0165 0.0559
Schistosoma mansoni glutamate synthase 0.0265 0.0591 0.0591
Schistosoma mansoni protein kinase 0.0227 0.0456 0.0456
Leishmania major casein kinase, putative 0.021 0.0395 0.0304
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0311 0.0759 0.0759
Schistosoma mansoni tyrosine kinase 0.0181 0.0289 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.1142 0.1142
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0171 0.0254 0.0765
Echinococcus granulosus hypothetical protein 0.088 0.2807 0.2807
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0269 0.0606 0.0517
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0326 0.0813 0.0813
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0158 0.0205 0.0199
Loa Loa (eye worm) AGC/PKN protein kinase 0.0562 0.1661 0.1655
Toxoplasma gondii AGC kinase 0.055 0.1619 0.158
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.023 0.0465 0.0375
Loa Loa (eye worm) LAD-2 short isoform 0.0163 0.0224 0.0217
Echinococcus granulosus titin 0.0218 0.0424 0.0424
Echinococcus multilocularis dual specificity 0.0269 0.0606 0.0606
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3165
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0308 0.0746 0.0728
Brugia malayi Serine/threonine-protein kinase SULU 0.043 0.1185 0.1168
Brugia malayi Protein kinase domain containing protein 0.0578 0.1721 0.1705
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0997 0.3229 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0265 0.0591 0.0573
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0294 0.0698 0.0698
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0291 0.0685 0.0685
Brugia malayi Protein kinase domain containing protein 0.0375 0.0987 0.097
Loa Loa (eye worm) hypothetical protein 0.0202 0.0364 0.0357
Entamoeba histolytica protein kinase, putative 0.0176 0.0272 0.0985
Echinococcus multilocularis cyclin dependent kinase 5 0.023 0.0465 0.0465
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3229
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0762 0.2382 0.2382
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.03 0.0717 0.0711
Entamoeba histolytica protein kinase, putative 0.0269 0.0606 0.2194
Echinococcus multilocularis neural cadherin 0.0291 0.0685 0.0685
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0218 0.0424 0.0417
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0381 0.101 0.1004
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0265 0.0591 0.0547
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.03 0.0717 0.0711
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Brugia malayi C1-like domain containing protein 0.0421 0.1153 0.1136
Echinococcus multilocularis 0.0233 0.0478 0.0478
Onchocerca volvulus 0.0291 0.0685 0.2636
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0164 0.0228 0.0824
Brugia malayi Immunoglobulin I-set domain containing protein 0.0219 0.0425 0.0407
Loa Loa (eye worm) TK protein kinase 0.0356 0.0922 0.0915
Echinococcus multilocularis 0.0296 0.0704 0.0704
Loa Loa (eye worm) hypothetical protein 0.0541 0.1585 0.1579
Loa Loa (eye worm) AUR protein kinase 0.0227 0.0456 0.0449
Brugia malayi cyclin-dependent kinase 9 0.0156 0.0198 0.018
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus Peroxidasin homolog 0.0137 0.0133 0.0432
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0226 0.0453 0.0435
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0137 0.0133 0.0133
Echinococcus granulosus Protein kinase C brain isozyme 0.0471 0.1334 0.1334
Schistosoma mansoni serine/threonine protein kinase 0.043 0.1185 0.1185
Giardia lamblia Kinase, NEK 0.0263 0.0586 0.158
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0388 0.1035 0.1035
Giardia lamblia Glutamate synthase 0.0265 0.0591 0.1596
Giardia lamblia Kinase, CMGC SRPK 0.0161 0.0217 0.0404
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Echinococcus granulosus cyclin 0.0855 0.2717 0.2717
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0361 0.0937 0.0937
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0265 0.0591 0.0547
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0107 0.0024 0.0017
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0997 0.3229 0.3165
Schistosoma mansoni serine/threonine protein kinase 0.0922 0.2958 0.2958
Onchocerca volvulus 0.0137 0.0131 0.0425
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0126 0.009 0.0137
Brugia malayi Heparan sulfate 0.0163 0.0224 0.0206
Loa Loa (eye worm) hypothetical protein 0.0521 0.1515 0.1509
Echinococcus multilocularis Glutaredoxin protein 5 0.0239 0.0498 0.0498
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.0518 0.1586
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0265 0.0591 0.1812
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0465 0.0465
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0265 0.0591 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Leishmania major hypothetical protein, conserved 0.0265 0.0591 0.0502
Echinococcus granulosus hemicentin 1 0.03 0.0717 0.0717
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0296 0.0704 0.0698
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0284 0.0662 0.2034
Entamoeba histolytica PH domain containing protein kinase, putative 0.0233 0.0478 0.173
Brugia malayi Protein kinase domain containing protein 0.0174 0.0263 0.0245
Echinococcus multilocularis protein tyrosine kinase 0.0553 0.1629 0.1629
Brugia malayi Casein kinase II, alpha chain 0.0194 0.0335 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.1334 0.1334
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0157 0.0204 0.0185
Echinococcus granulosus serine:threonine protein kinase TAO1 0.043 0.1185 0.1185
Echinococcus granulosus serine threonine protein kinase nrc 0.0303 0.0728 0.0728
Giardia lamblia High cysteine protein 0.0291 0.0685 0.1895
Schistosoma mansoni rap gtpase-activating protein 0.0216 0.0415 0.0415
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0155 0.0195 0.0195
Mycobacterium ulcerans hypothetical protein 0.0265 0.0591 0.1711
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0208 0.0388 0.0381
Giardia lamblia Thioredoxin reductase 0.0265 0.0591 0.1596
Entamoeba histolytica serine/threonine protein kinase, putative 0.0522 0.1519 0.5503
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0537 0.1571 0.1565
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0427 0.1176 0.1176
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0162 0.0221 0.0129
Brugia malayi putative serine/threonine kinase SADA gamma 0.0151 0.0182 0.0164
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.02 0.0356 0.0356
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0265 0.0591 0.1812
Echinococcus granulosus cyclin dependent kinase 5 0.023 0.0465 0.0465
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis casein kinase I alpha 0.021 0.0395 0.0395
Schistosoma mansoni septate junction protein 0.0163 0.0224 0.0224
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0265 0.0591 0.214
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0762 0.2382 0.2377
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0303 0.0728 0.0685
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0265 0.0591 0.1711
Schistosoma mansoni roundabout 0.03 0.0717 0.0717
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0236 0.0489 0.0483
Onchocerca volvulus 0.0291 0.0685 0.2636
Echinococcus multilocularis c src tyrosine kinase 0.0181 0.0289 0.0289
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0997 0.3229 1
Schistosoma mansoni c4b-binding protein beta chain 0.0537 0.1571 0.1571
Brugia malayi Animal haem peroxidase family protein 0.0137 0.0131 0.0112
Entamoeba histolytica casein kinase, putative 0.0194 0.0335 0.1214
Brugia malayi Prion-like- 0.0137 0.0131 0.0112
Schistosoma mansoni cell adhesion molecule 0.0154 0.0194 0.0194
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0265 0.0591 0.0573
Onchocerca volvulus 0.0126 0.0092 0.027
Echinococcus multilocularis mitogen activated protein kinase 14 0.0308 0.0746 0.0746
Echinococcus multilocularis protein jagged 1 0.0291 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus granulosus dual specificity 0.0269 0.0606 0.0606
Brugia malayi Leucine Rich Repeat family protein 0.0137 0.0133 0.0114
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0392 0.1049 0.1049
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.0433 0.0433
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0558 0.1648 0.1642
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0157 0.0202 0.0157
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus multilocularis serine:threonine protein kinase N2 0.0311 0.0759 0.0759
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Plasmodium falciparum cGMP-dependent protein kinase 0.0162 0.0222 0.0177
Brugia malayi Immunoglobulin domain containing protein 0.0163 0.0224 0.0206
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Echinococcus multilocularis Immunoglobulin 0.0163 0.0224 0.0224
Echinococcus multilocularis death associated protein kinase 1 0.0854 0.2712 0.2712
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Schistosoma mansoni kinase 0.0156 0.0198 0.0198
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0311 0.0759 0.0759
Echinococcus multilocularis rac serine:threonine kinase 0.0317 0.0781 0.0781
Brugia malayi Protein kinase domain containing protein 0.0331 0.083 0.0813
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0137 0.0131 0.0131
Toxoplasma gondii CMGC kinase, CK2 family 0.0194 0.0335 0.029
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.018 0.0287 0.0287
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Brugia malayi hypothetical protein 0.0216 0.0415 0.0397
Schistosoma mansoni tyrosine kinase 0.0362 0.0943 0.0943
Echinococcus granulosus titin 0.0218 0.0424 0.0424
Echinococcus granulosus tyrosine protein kinase Src64B 0.0294 0.0698 0.0698
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0221 0.0221
Plasmodium vivax tyrosine kinase-like protein, putative 0.0157 0.0202 0.0157
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0955 0.3079 0.3079
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0489 0.0489
Entamoeba histolytica protein kinase, putative 0.0249 0.0534 0.1934
Schistosoma mansoni tyrosine kinase 0.0578 0.1721 0.1721
Toxoplasma gondii rhoptry neck protein RON1 0.0537 0.1571 0.1532
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0181 0.0289 0.0289
Brugia malayi Protein kinase domain containing protein 0.0709 0.2191 0.2176
Echinococcus multilocularis tyrosine protein kinase Blk 0.024 0.0501 0.0501
Echinococcus granulosus protein kinase C gamma type 0.039 0.1043 0.1043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0415 0.0325
Plasmodium falciparum protein kinase, putative 0.0127 0.0093 0.0047
Onchocerca volvulus 0.0565 0.1671 0.6573
Echinococcus granulosus glutamate synthase 0.0265 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0558 0.1648 0.1642
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0294 0.0698 0.0698
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus multilocularis nervana 2 0.0239 0.0498 0.0498
Trypanosoma brucei casein kinase I, isoform 2 0.021 0.0395 0.0304
Echinococcus granulosus casein kinase I delta 0.021 0.0395 0.0395
Echinococcus multilocularis cyclin dependent kinase 9 0.0172 0.0256 0.0256
Onchocerca volvulus Slit protein homolog 0.0334 0.0839 0.3251
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0681 0.2092 0.2087
Leishmania major protein kinase A catalytic subunit isoform 2 0.0219 0.0425 0.0335
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0361 0.0937 0.092
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0265 0.0591 0.0547
Onchocerca volvulus 0.0249 0.0534 0.2034
Echinococcus granulosus neuroglian 0.0317 0.078 0.078
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0219 0.0425 0.0407
Echinococcus granulosus leucine rich repeat containing protein 4 0.0137 0.0131 0.0131
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0294 0.0698 0.0698
Brugia malayi Protein kinase domain containing protein 0.0236 0.0489 0.0471
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0303 0.0728 0.0685
Schistosoma mansoni protein kinase C mu 0.0421 0.1153 0.1153
Schistosoma mansoni protein kinase 0.0166 0.0237 0.0237
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.023 0.0465 0.0375
Brugia malayi STE20-like kinase MST 0.0496 0.1426 0.141
Echinococcus multilocularis cyclin 0.0855 0.2717 0.2717
Schistosoma mansoni nck2/grb4 0.0118 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.055 0.1619 0.1613
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0249 0.0534 0.0534
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0297 0.0708 0.0701
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0126 0.0092 0.0092
Giardia lamblia Kinase, PLK 0.0522 0.1519 0.4554
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.1334 0.1334
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Schistosoma mansoni cell adhesion molecule 0.03 0.0717 0.0717
Onchocerca volvulus 0.0137 0.0131 0.0425
Echinococcus multilocularis neurogenic locus protein delta 0.0291 0.0685 0.0685
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0151 0.0182 0.0175
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0294 0.0698 0.0698
Onchocerca volvulus 0.0126 0.0092 0.027
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0219 0.0425 0.0407
Schistosoma mansoni nephrin 0.0695 0.2141 0.2141
Brugia malayi Immunoglobulin I-set domain containing protein 0.0317 0.078 0.0763
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0161 0.0217 0.0198
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0732 0.2275 0.2261
Trypanosoma brucei trypanothione reductase 0.2877 1 1
Schistosoma mansoni protein kinase 0.0194 0.0335 0.0335
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0511 0.1478 0.1472
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Giardia lamblia NADH oxidase lateral transfer candidate 0.0997 0.3229 1
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0471 0.1334 0.1334
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0997 0.3229 0.3165
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Plasmodium falciparum casein kinase 2, alpha subunit 0.0194 0.0335 0.029
Plasmodium vivax serine/threonine kinase-1, putative 0.0297 0.0708 0.0664
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0106 0.0019 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Loa Loa (eye worm) hypothetical protein 0.0126 0.0092 0.0085
Echinococcus granulosus tyrosine protein kinase shark 0.0333 0.0837 0.0837
Schistosoma mansoni hypothetical protein 0.0265 0.0591 0.0591
Schistosoma mansoni protein kinase 0.0127 0.0093 0.0093
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0867 0.276 0.2755
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0522 0.1519 0.1513
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0762 0.2382 0.2382
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0265 0.0591 0.0591
Echinococcus granulosus tyrosine protein kinase Srms 0.0521 0.1514 0.1514
Echinococcus multilocularis epidermal growth factor receptor 0.0667 0.2038 0.2038
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0241 0.0506 0.0416
Echinococcus multilocularis slit 2 protein 0.0334 0.0839 0.0839
Plasmodium vivax glutathione reductase, putative 0.2877 1 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3229
Loa Loa (eye worm) hypothetical protein 0.0265 0.0591 0.0584
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0156 0.0198 0.0191
Echinococcus multilocularis expressed protein 0.0161 0.0217 0.0217
Echinococcus multilocularis activin receptor type 0.0127 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Entamoeba histolytica protein kinase domain containing protein 0.0156 0.0198 0.0717
Brugia malayi Myb-like DNA-binding domain containing protein 0.0137 0.0131 0.0112
Loa Loa (eye worm) hypothetical protein 0.0448 0.1252 0.1246
Brugia malayi Cyclin, N-terminal domain containing protein 0.0855 0.2717 0.2703
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0709 0.2191 0.2191
Loa Loa (eye worm) TK/ROR protein kinase 0.02 0.0356 0.035
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0126 0.009 0.0137
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0294 0.0698 0.0698
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0162 0.0221 0.0176
Echinococcus granulosus basement membrane specific heparan sulfate 0.0163 0.0224 0.0224
Echinococcus granulosus CDC7 cell division cycle 7 0.0174 0.0263 0.0263
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0265 0.0591 0.1711
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus Immunoglobulin 0.0163 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus granulosus tyrosine kinase 0.0126 0.0092 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0425 0.0425
Toxoplasma gondii rhoptry neck protein RON9 0.0537 0.1571 0.1532
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0151 0.0182 0.0164
Echinococcus granulosus Immunoglobulin 0.0541 0.1585 0.1585
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0162 0.0221 0.0203
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0194 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Loa Loa (eye worm) AGC/PKA protein kinase 0.0219 0.0425 0.0418
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0265 0.0591 0.1711
Onchocerca volvulus 0.021 0.0395 0.1478
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0157 0.0157
Schistosoma mansoni growth factor receptor-bound protein 0.0118 0.0064 0.0064
Entamoeba histolytica protein kinase, putative 0.0236 0.0489 0.1772
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0265 0.0591 0.0547
Leishmania major protein kinase, putative 0.0297 0.0708 0.062
Mycobacterium tuberculosis Probable dehydrogenase 0.0265 0.0591 0.0547
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0249 0.0534 0.0445
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0541 0.1585 0.1585
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0269 0.0606 0.0562
Brugia malayi Prion-like- 0.0137 0.0131 0.0112
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0227 0.0456 0.165
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0373 0.098 0.0974
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.0433 0.0433
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Onchocerca volvulus 0.0126 0.0092 0.027
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0997 0.3229 0.3216
Echinococcus multilocularis cyclin dependent kinase 1 0.023 0.0465 0.0465
Trypanosoma brucei polo-like protein kinase 0.0522 0.1519 0.1439
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0219 0.0425 0.0335
Echinococcus multilocularis Immunoglobulin 0.0541 0.1585 0.1585
Brugia malayi Protein kinase domain containing protein 0.0311 0.0759 0.0741
Loa Loa (eye worm) TK protein kinase 0.0176 0.0272 0.0265
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0265 0.0591 0.0573
Loa Loa (eye worm) hypothetical protein 0.0268 0.0604 0.0597
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.034 0.1035
Trypanosoma cruzi aurora B kinase, putative 0.0227 0.0456 0.0438
Loa Loa (eye worm) hypothetical protein 0.0157 0.0205 0.0198
Onchocerca volvulus 0.0126 0.0092 0.027
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.0606 0.0606
Trichomonas vaginalis AGC family protein kinase 0.0327 0.0816 0.2513
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0303 0.0728 0.0711
Echinococcus multilocularis ephrin type A receptor 4 A 0.0186 0.0309 0.0309
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0158 0.0205 0.0205
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0236 0.0489 0.0471
Echinococcus granulosus casein kinase ii subunit alpha 0.0194 0.0335 0.0335
Giardia lamblia Kinase, CMGC CDK 0.023 0.0465 0.1196
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0157 0.0204 0.0204
Brugia malayi Protein kinase domain containing protein 0.0559 0.165 0.1634
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Trypanosoma cruzi cdc2-related kinase 1 0.023 0.0465 0.0447
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Schistosoma mansoni serine/threonine protein kinase 0.0628 0.1901 0.1901
Schistosoma mansoni septate junction protein 0.03 0.0717 0.0717
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus multilocularis tyrosine protein kinase otk 0.03 0.0717 0.0717
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0157 0.0204 0.0112
Plasmodium falciparum serine/threonine protein kinase, putative 0.0227 0.0456 0.0411
Brugia malayi Protein kinase domain 0.0166 0.0237 0.0219
Brugia malayi Immunoglobulin I-set domain containing protein 0.0317 0.078 0.0763
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0997 0.3229 0.3216
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0997 0.3229 0.3197
Plasmodium falciparum ferrodoxin reductase-like protein 0.0265 0.0591 0.0547
Schistosoma mansoni tyrosine kinase 0.0402 0.1087 0.1087
Brugia malayi Temporarily assigned gene name protein 59 0.0216 0.0415 0.0397
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Treponema pallidum NADH oxidase 0.0997 0.3229 1
Echinococcus granulosus neuroglian 0.0678 0.2078 0.2078
Onchocerca volvulus 0.0154 0.0194 0.0676
Echinococcus multilocularis tyrosine kinase 0.0126 0.0092 0.0092
Onchocerca volvulus 0.0137 0.0131 0.0425
Schistosoma mansoni serine/threonine kinase 0.0311 0.0759 0.0759
Loa Loa (eye worm) hypothetical protein 0.0892 0.2849 0.2844
Trichomonas vaginalis glutamate synthase, putative 0.0265 0.0591 0.1812
Echinococcus granulosus low density lipoprotein receptor ldl 0.0163 0.0224 0.0224
Onchocerca volvulus 0.0218 0.0424 0.1595
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0326 0.0813 0.0813
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0997 0.3229 1
Schistosoma mansoni adapter molecule crk 0.0118 0.0064 0.0064
Brugia malayi Furin-like cysteine rich region family protein 0.0667 0.2038 0.2023
Schistosoma mansoni neuroglian 0.0317 0.078 0.078
Echinococcus multilocularis tyrosine protein kinase shark 0.0333 0.0837 0.0837
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0221 0.0433 0.0426
Toxoplasma gondii thioredoxin reductase 0.2877 1 1
Loa Loa (eye worm) hypothetical protein 0.0166 0.0235 0.0228
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0157 0.0204 0.0204
Echinococcus multilocularis casein kinase ii subunit alpha 0.0194 0.0335 0.0335
Onchocerca volvulus 0.0216 0.0415 0.1561
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0265 0.0591 0.0573
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0392 0.1049 0.1049
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0162 0.0221 0.0203
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0163 0.0224 0.0224
Brugia malayi Protein kinase domain containing protein 0.0412 0.1122 0.1106
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0222 0.0222
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0158 0.0205 0.0205
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0308 0.0746 0.0659
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0291 0.0685 0.0667
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0143 0.0153 0.0146
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0317 0.078 0.078
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.028 0.0646 0.0646
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0239 0.0498 0.0498
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus 0.0603 0.1811 0.7131
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0157 0.0204 0.0185
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.1274 0.1274
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Brugia malayi serine/threonine kinase 12 0.0227 0.0456 0.0438
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0219 0.0425 0.0407
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) protein kinase domain-containing protein 0.0412 0.1122 0.1116
Echinococcus granulosus protein jagged 1 0.0291 0.0685 0.0685
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Brugia malayi notch-like transmembrane receptor 0.0291 0.0685 0.0667
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0596 0.1784 0.1784
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0279 0.0279
Echinococcus multilocularis protein kinase c iota type 0.0552 0.1627 0.1627
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0155 0.0195 0.0195
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0839 0.2658 0.2658
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0331 0.083 0.0823
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0118 0.0064 0.0064
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0265 0.0591 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Echinococcus multilocularis dual specificity 0.0269 0.0606 0.0606
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0265 0.0591 0.1711
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0167 0.024 0.0195
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0997 0.3229 0.3197
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Loa Loa (eye worm) AUR protein kinase 0.0227 0.0456 0.0449
Echinococcus multilocularis casein kinase I delta 0.021 0.0395 0.0395
Loa Loa (eye worm) thioredoxin reductase 0.2877 1 1
Onchocerca volvulus 0.0137 0.0133 0.0432
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1369 0.457 0.4566
Trypanosoma brucei cdc2-related kinase 3 0.023 0.0465 0.0375
Schistosoma mansoni peroxidasin 0.0163 0.0226 0.0226
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0163 0.0224 0.0224
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0019 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0425 0.0425
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0265 0.0591 0.0591
Echinococcus granulosus neurogenic locus notch protein 0.0291 0.0685 0.0685
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0236 0.0489 0.0399
Echinococcus granulosus C type lectin domian containing protein 0.0537 0.1571 0.1571
Schistosoma mansoni protein kinase 0.0166 0.0237 0.0237
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.028 0.0646 0.0646
Schistosoma mansoni cell adhesion molecule 0.0163 0.0224 0.0224
Schistosoma mansoni protein kinase 0.0709 0.2191 0.2191

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 8 nM Effective concentration towards 5-hydroxytryptamine 2A receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 8 nM Effective concentration towards 5-hydroxytryptamine 2A receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 100 nM Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 100 nM Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 400 nM Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 400 nM Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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