Detailed information for compound 314165

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 646.901 | Formula: C26H46N4O9SSi2
  • H donors: 2 H acceptors: 5 LogP: 2.56 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: NC(=O)NC1=CS(=O)(=O)OC21C(CO[Si](C(C)(C)C)(C)C)OC(C2O[Si](C(C)(C)C)(C)C)n1cc(C)c(=O)n(c1=O)C
  • InChi: 1S/C26H46N4O9SSi2/c1-16-13-30(23(33)29(8)20(16)31)21-19(38-42(11,12)25(5,6)7)26(17(28-22(27)32)15-40(34,35)39-26)18(37-21)14-36-41(9,10)24(2,3)4/h13,15,18-19,21H,14H2,1-12H3,(H3,27,28,32)
  • InChiKey: WLVIZZINIAXMQK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Thioredoxin reductase 0.4142 1 1
Loa Loa (eye worm) AGC/PKG protein kinase 0.0173 0.0124 0.0116
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0418 0.0734 0.0734
Echinococcus granulosus fibropellin Ia 0.0419 0.0735 0.0735
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0381 0.0642 0.1907
Onchocerca volvulus 0.0135 0.0029 0.0057
Echinococcus multilocularis tyrosine protein kinase Blk 0.0256 0.0331 0.0331
Schistosoma mansoni nephrin related 0.0187 0.0158 0.015
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0281 0.0392 0.0365
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus multilocularis mitogen activated protein kinase 0.0173 0.0123 0.0123
Loa Loa (eye worm) TK protein kinase 0.0561 0.1089 0.1082
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0482 0.0475
Echinococcus multilocularis mitogen activated protein kinase 14 0.0328 0.051 0.051
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0224 0.0251 0.0243
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Schistosoma mansoni tyrosine kinase 0.0288 0.041 0.0402
Brugia malayi Immunoglobulin I-set domain containing protein 0.0431 0.0765 0.0757
Schistosoma mansoni protein kinase 0.0456 0.0828 0.082
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Echinococcus granulosus cyclin dependent kinase 19 0.1043 0.2289 0.2289
Loa Loa (eye worm) hypothetical protein 0.0735 0.1523 0.1516
Onchocerca volvulus Tyrosine kinase homolog 0.0898 0.1929 1
Loa Loa (eye worm) CAMK protein kinase 0.0273 0.0373 0.0365
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0154 0.0403
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1435 0.3265 1
Echinococcus multilocularis casein kinase I alpha 0.0224 0.0251 0.0251
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0296 0.0842
Brugia malayi Protein kinase domain containing protein 0.0168 0.0112 0.0104
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0123 0.0308
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0233 0.0274 0.0245
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0363 0.0596 0.0588
Onchocerca volvulus 0.0295 0.0428 0.2142
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0224 0.0251 0.0243
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0261 0.0343 0.0335
Echinococcus multilocularis roundabout 2 0.0431 0.0765 0.0765
Entamoeba histolytica protein kinase domain containing protein 0.0418 0.0734 0.4432
Loa Loa (eye worm) thyroid receptor interactor 0.0211 0.0219 0.0211
Entamoeba histolytica protein kinase, putative 0.0242 0.0296 0.1702
Entamoeba histolytica protein kinase, putative 0.0208 0.0211 0.117
Loa Loa (eye worm) hypothetical protein 0.0412 0.0718 0.0711
Echinococcus multilocularis tyrosine protein kinase Srms 0.0256 0.0331 0.0331
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0177 0.0135 0.0135
Schistosoma mansoni tyrosine kinase 0.0497 0.093 0.0923
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0242 0.0296 0.1702
Schistosoma mansoni growth factor receptor-bound protein 0.0128 0.0013 0.0005
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0233 0.0274 0.0245
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0381 0.0642 0.0615
Toxoplasma gondii rhoptry neck protein RON1 0.0773 0.1617 0.1592
Echinococcus multilocularis rac serine:threonine kinase 0.0339 0.0536 0.0536
Onchocerca volvulus 0.0419 0.0735 0.3753
Echinococcus multilocularis neural cadherin 0.0419 0.0735 0.0735
Echinococcus granulosus delta-like protein 1 0.0419 0.0735 0.0735
Schistosoma mansoni titin 0.0187 0.0158 0.015
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0418 0.0734 0.0726
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0154 0.0403
Echinococcus multilocularis calcium activated potassium channel 0.0278 0.0386 0.0386
Loa Loa (eye worm) hypothetical protein 0.0231 0.0268 0.026
Echinococcus multilocularis casein kinase ii subunit alpha 0.0206 0.0207 0.0207
Echinococcus granulosus basement membrane specific heparan sulfate 0.0225 0.0254 0.0254
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0315 0.0476 0.0476
Brugia malayi Tyrosine-protein kinase abl-1 0.0193 0.0175 0.0167
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0173 0.0124 0.0124
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0431 0.0765 0.0757
Brugia malayi Protein kinase domain containing protein 0.0728 0.1504 0.1497
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0132 0.0335
Trichomonas vaginalis STE family protein kinase 0.0177 0.0135 0.0344
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1435 0.3265 0.3246
Trypanosoma cruzi cdc2-related kinase 1 0.0245 0.0303 0.0275
Schistosoma mansoni cell adhesion molecule 0.0187 0.0158 0.015
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0766 0.1599 0.1599
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0381 0.0642 0.0615
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0208 0.0211 0.0183
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0136 0.0031 0.0048
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0485 0.09 0.09
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1081 0.3263
Loa Loa (eye worm) hypothetical protein 0.0231 0.0268 0.026
Brugia malayi serine/threonine kinase 12 0.0242 0.0296 0.0288
Schistosoma mansoni notch 0.0419 0.0735 0.0728
Brugia malayi protein-tyrosine kinase 0.0256 0.0331 0.0323
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0152 0.0072 0.0064
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1435 0.3265 0.3246
Loa Loa (eye worm) projectin 0.0205 0.0204 0.0197
Loa Loa (eye worm) TK protein kinase 0.0188 0.0162 0.0154
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0208 0.0211 0.0203
Entamoeba histolytica hypothetical protein 0.0393 0.0673 0.4051
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0718 0.0711
Echinococcus granulosus titin 0.0187 0.0158 0.0158
Schistosoma mansoni basigin related 0.0225 0.0254 0.0246
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1435 0.3265 1
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0094 0.0086
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1435 0.3265 0.3246
Loa Loa (eye worm) hypothetical protein 0.0382 0.0644 0.0636
Echinococcus granulosus c4b binding protein beta chain 0.0773 0.1617 0.1617
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0225 0.0254 0.0246
Onchocerca volvulus 0.0773 0.1617 0.8367
Brugia malayi Protein kinase domain containing protein 0.0398 0.0683 0.0676
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0312 0.1803
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0173 0.0123 0.0095
Echinococcus granulosus thioredoxin glutathione reductase 0.4142 1 1
Loa Loa (eye worm) hypothetical protein 0.0754 0.157 0.1563
Brugia malayi serine/threonine-protein kinase plk-2 0.0558 0.1081 0.1074
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0407 0.0399
Brugia malayi Protein kinase domain containing protein 0.0448 0.0808 0.08
Echinococcus multilocularis transfer RNA-Phe 0.0205 0.0204 0.0204
Loa Loa (eye worm) one IG domain family member 0.0187 0.0158 0.015
Trypanosoma cruzi aurora B kinase, putative 0.0242 0.0296 0.0268
Echinococcus granulosus notch 0.0419 0.0735 0.0735
Toxoplasma gondii histone kinase SNF1, putative 0.0161 0.0094 0.0066
Echinococcus multilocularis dual specificity 0.0287 0.0407 0.0407
Echinococcus granulosus casein kinase I alpha 0.0224 0.0251 0.0251
Schistosoma mansoni atypical protein kinase C 0.0602 0.1192 0.1185
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0225 0.0254 0.0246
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0268 0.024
Entamoeba histolytica p21-activated kinase 0.0193 0.0174 0.0938
Schistosoma mansoni ste20-related kinase 0.0423 0.0747 0.0739
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0257 0.0333 0.0305
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0187 0.0159 0.0159
Loa Loa (eye worm) hypothetical protein 0.0464 0.0849 0.0842
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Brugia malayi Egg laying defective protein 4 0.0173 0.0124 0.0116
Schistosoma mansoni peroxidasin 0.0226 0.0256 0.0248
Schistosoma mansoni hypothetical protein 0.0187 0.0158 0.015
Entamoeba histolytica protein kinase, putative 0.0603 0.1194 0.7303
Schistosoma mansoni serine/threonine protein kinase 0.0338 0.0536 0.0528
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0419 0.0735 0.0728
Brugia malayi Protein kinase domain containing protein 0.0618 0.1232 0.1224
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0256 0.0331 0.0331
Echinococcus multilocularis serine:threonine protein kinase N2 0.06 0.1186 0.1186
Echinococcus multilocularis neurogenic locus notch protein 0.0419 0.0735 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0984 0.2143 0.2137
Brugia malayi Serine/threonine-protein kinase SULU 0.0458 0.0834 0.0827
Giardia lamblia Kinase, NEK 0.0281 0.0392 0.0881
Echinococcus multilocularis Immunoglobulin subtype 0.0225 0.0254 0.0254
Entamoeba histolytica protein kinase, putative 0.0603 0.1194 0.7303
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Echinococcus granulosus tyrosine kinase 0.0256 0.0331 0.0331
Echinococcus multilocularis protein kinase c iota type 0.0589 0.116 0.116
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0168 0.0112 0.0112
Schistosoma mansoni glutamate synthase 0.0381 0.0642 0.0634
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Echinococcus granulosus down syndrome cell adhesion 0.0187 0.0158 0.0158
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0735 0.1523 0.1516
Echinococcus multilocularis cyclin dependent kinase 1 0.0245 0.0303 0.0303
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0233 0.0274 0.0266
Echinococcus granulosus insulin growth factor binding 0.0187 0.0158 0.0158
Brugia malayi Protein kinase domain containing protein 0.0185 0.0154 0.0146
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Onchocerca volvulus 0.0381 0.0642 0.3267
Schistosoma mansoni sulfide quinone reductase 0.0381 0.0642 0.0634
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.09 0.0893
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1501 0.3429 0.3429
Schistosoma mansoni septate junction protein 0.0412 0.0718 0.0711
Echinococcus multilocularis serine:threonine protein kinase 38 0.0332 0.052 0.052
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0123 0.0095
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1435 0.3265 0.3246
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0449 0.0811 0.0803
Echinococcus multilocularis rho associated protein kinase 0.0671 0.1363 0.1363
Schistosoma mansoni titin 0.0187 0.0158 0.015
Giardia lamblia NADH oxidase lateral transfer candidate 0.1435 0.3265 1
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Brugia malayi Protein kinase domain containing protein 0.0312 0.047 0.0462
Loa Loa (eye worm) hypothetical protein 0.0132 0.0023 0.0015
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0381 0.0642 0.1907
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Schistosoma mansoni nephrin related 0.0225 0.0254 0.0246
Plasmodium falciparum calcium-dependent protein kinase 3 0.0208 0.0211 0.0183
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1183
Brugia malayi Protein kinase domain containing protein 0.044 0.0788 0.0781
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0381 0.0642 0.1907
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0482 0.0475
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Brugia malayi Hr1 repeat family protein 0.06 0.1186 0.1179
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0208 0.0211 0.0203
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0814 0.1718 0.1711
Echinococcus multilocularis down syndrome cell adhesion 0.0187 0.0158 0.0158
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0407 0.0379
Schistosoma mansoni hypothetical protein 0.0225 0.0254 0.0246
Echinococcus granulosus Immunoglobulin 0.0735 0.1523 0.1523
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0328 0.051 0.0483
Schistosoma mansoni tyrosine kinase 0.0193 0.0175 0.0167
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0814 0.1718 0.1718
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0233 0.0274 0.0245
Plasmodium falciparum calcium-dependent protein kinase 1 0.0208 0.0211 0.0183
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0381 0.0642 0.1907
Loa Loa (eye worm) hypothetical protein 0.0479 0.0885 0.0878
Loa Loa (eye worm) TK/EPH protein kinase 0.0235 0.0279 0.0271
Giardia lamblia Kinase, CMGC CLK 0.0317 0.0482 0.1166
Schistosoma mansoni tyrosine kinase 0.0618 0.1232 0.1224
Brugia malayi Furin-like cysteine rich region family protein 0.0712 0.1466 0.1459
Onchocerca volvulus 0.0187 0.0159 0.0738
Echinococcus granulosus raf serine:threonine protein kinase 0.0153 0.0075 0.0075
Brugia malayi Temporarily assigned gene name protein 59 0.0266 0.0356 0.0349
Echinococcus granulosus dual specificity 0.0287 0.0407 0.0407
Echinococcus granulosus slit 2 protein 0.0464 0.0849 0.0849
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0655 0.1323 0.1316
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Brugia malayi casein kinase 1, delta 0.0224 0.0251 0.0243
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0261 0.0343 0.0343
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0231 0.0268 0.0268
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0174 0.0128 0.0099
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0449 0.0811 0.0811
Trypanosoma brucei trypanothione reductase 0.4142 1 1
Echinococcus multilocularis casein kinase I gamma 0.044 0.0788 0.0788
Schistosoma mansoni serine/threonine protein kinase 0.044 0.0788 0.0781
Loa Loa (eye worm) TK/INSR protein kinase 0.0618 0.1232 0.1224
Brugia malayi P38 map kinase family protein 2 0.0328 0.051 0.0503
Echinococcus multilocularis tyrosine protein kinase shark 0.0356 0.0579 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0123 0.0115
Loa Loa (eye worm) TK protein kinase 0.0256 0.0331 0.0323
Loa Loa (eye worm) hypothetical protein 0.0233 0.0274 0.0266
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1081 0.1056
Giardia lamblia Kinase, AGC PKA 0.0323 0.0498 0.1215
Brugia malayi Kinase associated domain 1 family protein 0.021 0.0217 0.0209
Schistosoma mansoni septate junction protein 0.0412 0.0718 0.0711
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0381 0.0642 0.0615
Giardia lamblia Kinase, AGC AKT 0.0241 0.0294 0.057
Mycobacterium tuberculosis Probable oxidoreductase 0.1435 0.3265 0.2803
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0225 0.0254 0.0254
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0381 0.0642 0.0615
Trypanosoma brucei hypothetical protein, conserved 0.0381 0.0642 0.0615
Onchocerca volvulus 0.0773 0.1617 0.8367
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0204 0.0197
Echinococcus multilocularis epidermal growth factor receptor 0.0712 0.1466 0.1466
Leishmania major protein kinase, putative 0.0317 0.0482 0.0455
Echinococcus granulosus titin 0.0187 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Giardia lamblia Kinase, CMGC DYRK 0.0287 0.0407 0.0927
Brugia malayi Cam kinase protein 1 0.0208 0.0211 0.0203
Entamoeba histolytica hypothetical protein 0.0252 0.0321 0.1856
Plasmodium falciparum glycogen synthase kinase 3 0.0265 0.0354 0.0326
Entamoeba histolytica protein kinase, putative 0.0168 0.0112 0.055
Loa Loa (eye worm) hypothetical protein 0.0225 0.0254 0.0246
Trypanosoma brucei casein kinase I, isoform 2 0.0224 0.0251 0.0223
Brugia malayi Protein kinase domain containing protein 0.0127 0.0011 0.0003
Brugia malayi Protein kinase domain containing protein 0.0235 0.0279 0.0271
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0171 0.012 0.0112
Plasmodium falciparum serine/threonine protein kinase, putative 0.0242 0.0296 0.0268
Echinococcus granulosus roundabout 2 0.1166 0.2595 0.2595
Schistosoma mansoni basigin related 0.0225 0.0254 0.0246
Onchocerca volvulus Putative titin 0.0187 0.0158 0.0731
Echinococcus multilocularis nervana 2 0.0255 0.0329 0.0329
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0187 0.0158 0.015
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0315 0.0476 0.0476
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0381 0.0642 0.0642
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0317 0.0482 0.0475
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1435 0.3265 0.3246
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0698 0.1431 0.1424
Giardia lamblia Kinase, CMGC SRPK 0.0171 0.012 0.0016
Echinococcus multilocularis dual specificity 0.0287 0.0407 0.0407
Trypanosoma cruzi casein kinase, putative 0.0224 0.0251 0.0223
Brugia malayi Peroxidasin 0.0412 0.072 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0728 0.1504 0.1497
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0449 0.0811 0.0803
Giardia lamblia High cysteine protein 0.0419 0.0735 0.1968
Echinococcus multilocularis neuroglian 0.0922 0.1988 0.1988
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0381 0.0642 0.0615
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0273 0.0373 0.0365
Loa Loa (eye worm) hypothetical protein 0.0619 0.1233 0.1226
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1183
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0536 0.0529
Echinococcus granulosus Immunoglobulin subtype 0.0225 0.0254 0.0254
Schistosoma mansoni protein kinase 0.0316 0.048 0.0472
Brugia malayi Sushi domain 0.0773 0.1617 0.161
Brugia malayi Immunoglobulin I-set domain containing protein 0.0431 0.0765 0.0757
Schistosoma mansoni tyrosine kinase 0.0193 0.0175 0.0167
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0204 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0274 0.0266
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0303 0.0863
Echinococcus multilocularis casein kinase I alpha 0.0224 0.0251 0.0251
Brugia malayi Protein kinase domain containing protein 0.0597 0.118 0.1172
Echinococcus granulosus tyrosine protein kinase HCK 0.0188 0.0162 0.0162
Echinococcus granulosus N chimaerin 0.0154 0.0077 0.0077
Trichomonas vaginalis CK1 family protein kinase 0.0224 0.0251 0.0702
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Echinococcus multilocularis mitogen activated protein kinase 14 0.0328 0.051 0.051
Brugia malayi Prion-like- 0.0187 0.0158 0.015
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Schistosoma mansoni basigin related 0.0225 0.0254 0.0246
Echinococcus granulosus dual specificity 0.0287 0.0407 0.0407
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.1504 0.1497
Schistosoma mansoni g1/s-specific cyclin C 0.1536 0.3515 0.3509
Echinococcus multilocularis casein kinase I alpha 0.0224 0.0251 0.0251
Schistosoma mansoni tyrosine kinase 0.0712 0.1466 0.1459
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0458 0.0834 0.0834
Loa Loa (eye worm) hypothetical protein 0.0216 0.023 0.0222
Schistosoma mansoni tyrosine kinase 0.0413 0.0721 0.0714
Echinococcus granulosus roundabout 2 0.0431 0.0765 0.0765
Loa Loa (eye worm) thioredoxin reductase 0.4142 1 1
Echinococcus multilocularis casein kinase I delta 0.0224 0.0251 0.0251
Trypanosoma brucei aurora B kinase 0.0242 0.0296 0.0268
Trypanosoma brucei protein kinase, putative 0.0265 0.0354 0.0326
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Brugia malayi Prion-like- 0.0187 0.0158 0.015
Trypanosoma cruzi polo-like protein kinase, putative 0.0558 0.1081 0.1056
Giardia lamblia Kinase, STE STE20 0.0177 0.0135 0.0063
Echinococcus granulosus nervana 2 0.0255 0.0329 0.0329
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0558 0.1081 0.1056
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Brugia malayi Protein kinase c protein 2 0.0239 0.0287 0.0279
Entamoeba histolytica protein kinase, putative 0.0242 0.0296 0.1702
Loa Loa (eye worm) hypothetical protein 0.0249 0.0314 0.0306
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0245 0.0303 0.0275
Loa Loa (eye worm) Notch2 0.0419 0.0735 0.0728
Brugia malayi Myb-like DNA-binding domain containing protein 0.0187 0.0158 0.015
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0317 0.0482 0.0455
Loa Loa (eye worm) hypothetical protein 0.0295 0.0428 0.042
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0281 0.0392 0.0286
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Schistosoma mansoni protein kinase 0.0398 0.0683 0.0676
Plasmodium vivax apical sushi protein, putative 0.0773 0.1617 0.1524
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0381 0.0642 0.0642
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0225 0.0254 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0343 0.0335
Schistosoma mansoni roundabout 0.0412 0.0718 0.0711
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Brugia malayi Protein kinase domain containing protein 0.0926 0.1997 0.1991
Onchocerca volvulus 0.0135 0.0029 0.0057
Brugia malayi serine/threonine-protein kinase 6 0.0242 0.0296 0.0288
Schistosoma mansoni hemicentin 0.0205 0.0204 0.0197
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0208 0.0211 0.0211
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0381 0.0642 0.1907
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0381 0.0642 0.0642
Entamoeba histolytica serine/threonine protein kinase, putative 0.0161 0.0094 0.0443
Echinococcus granulosus serine/threonine protein kinase 0.0339 0.0536 0.0536
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0757 0.1577 0.157
Schistosoma mansoni hypothetical protein 0.0225 0.0254 0.0246
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0171 0.012 0.0091
Schistosoma mansoni tyrosine kinase 0.0591 0.1164 0.1157
Trichomonas vaginalis CAMK family protein kinase 0.0235 0.0279 0.0789
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0094 0.0086
Schistosoma mansoni tyrosine kinase 0.043 0.0764 0.0756
Echinococcus granulosus tyrosine protein kinase Blk 0.0256 0.0331 0.0331
Schistosoma mansoni tyrosine kinase 0.0479 0.0885 0.0878
Plasmodium vivax casein kinase 1, putative 0.0224 0.0251 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.0734 0.0726
Schistosoma mansoni tyrosine kinase 0.0618 0.1232 0.1224
Entamoeba histolytica cell division protein kinase 2, putative 0.0245 0.0303 0.1746
Giardia lamblia Kinase, CMGC CDK 0.0245 0.0303 0.0598
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1183
Onchocerca volvulus 0.0773 0.1617 0.8367
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Schistosoma mansoni cell adhesion molecule 0.0431 0.0765 0.0757
Trichomonas vaginalis CAMK family protein kinase 0.0208 0.0211 0.0579
Giardia lamblia Kinase, CMGC GSK 0.0265 0.0354 0.0759
Onchocerca volvulus 0.0645 0.1298 0.6698
Brugia malayi Protein kinase domain containing protein 0.0135 0.0029 0.0021
Echinococcus granulosus insulin receptor 0.0618 0.1232 0.1232
Echinococcus granulosus protein kinase c iota type 0.0589 0.116 0.116
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0252 0.0321 0.0293
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0077 0.0069
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Loa Loa (eye worm) hypothetical protein 0.0184 0.0152 0.0144
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Loa Loa (eye worm) animal heme peroxidase 0.0187 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0506 0.0952 0.0944
Loa Loa (eye worm) hypothetical protein 0.0953 0.2064 0.2058
Loa Loa (eye worm) programmed cell death 8 0.0381 0.0642 0.0634
Echinococcus granulosus titin 0.0273 0.0373 0.0373
Loa Loa (eye worm) TK/ALK protein kinase 0.0312 0.047 0.0462
Giardia lamblia Kinase, CK1 Casein kinase 0.0224 0.0251 0.0432
Echinococcus granulosus mitogen activated protein kinase 0.0173 0.0123 0.0123
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0256 0.0331 0.0331
Brugia malayi p70 ribosomal S6 kinase beta 0.0587 0.1155 0.1148
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0587 0.1155 0.1148
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0381 0.0642 0.0615
Echinococcus granulosus NCK adaptor protein 0.0126 0.0008 0.0008
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Entamoeba histolytica protein kinase, putative 0.0177 0.0135 0.0695
Echinococcus granulosus dual specificity 0.0287 0.0407 0.0407
Plasmodium falciparum calcium-dependent protein kinase 5 0.0208 0.0211 0.0183
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0154 0.0077 0.0069
Echinococcus granulosus tyrosine protein kinase ABL1 0.0135 0.0029 0.0029
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0161 0.0094 0.0066
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0187 0.0158 0.0158
Toxoplasma gondii AGC kinase 0.0233 0.0274 0.0245
Echinococcus granulosus cyclin 0.0766 0.1599 0.1599
Loa Loa (eye worm) TK/EGFR protein kinase 0.0712 0.1466 0.1459
Schistosoma mansoni tyrosine kinase 0.0497 0.093 0.0923
Schistosoma mansoni netrin receptor unc5 0.0285 0.0403 0.0395
Loa Loa (eye worm) hypothetical protein 0.0736 0.1525 0.1518
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1435 0.3265 0.326
Schistosoma mansoni cell adhesion molecule 0.0431 0.0765 0.0757
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Loa Loa (eye worm) hypothetical protein 0.0373 0.0622 0.0614
Leishmania major protein kinase A catalytic subunit isoform 1 0.0233 0.0274 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0332 0.052 0.0512
Plasmodium falciparum thioredoxin reductase 0.1435 0.3265 0.3246
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0225 0.0254 0.0254
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0431 0.0765 0.0765
Onchocerca volvulus Neurogenic locus notch homolog 0.0419 0.0735 0.3753
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0421 0.0741 0.0734
Brugia malayi Protein kinase domain containing protein 0.0135 0.0029 0.0021
Brugia malayi Protein kinase domain containing protein 0.0135 0.0029 0.0021
Echinococcus granulosus nervana 2 0.0255 0.0329 0.0329
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0381 0.0642 0.0642
Onchocerca volvulus 0.0773 0.1617 0.8367
Brugia malayi Delta serrate ligand family protein 0.0419 0.0735 0.0728
Brugia malayi Protein kinase domain containing protein 0.0289 0.0414 0.0406
Onchocerca volvulus 0.0773 0.1617 0.8367
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0381 0.0642 0.0615
Trichomonas vaginalis AGC family protein kinase 0.0369 0.0611 0.1813
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0252 0.0321 0.0293
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0233 0.0274 0.0245
Loa Loa (eye worm) hypothetical protein 0.0381 0.0642 0.0635
Loa Loa (eye worm) hypothetical protein 0.1191 0.2658 0.2652
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0204 0.0197
Echinococcus multilocularis cyclin dependent kinase 0.0245 0.0303 0.0303
Echinococcus multilocularis neurogenic locus notch protein 0.0419 0.0735 0.0735
Loa Loa (eye worm) hypothetical protein 0.0177 0.0135 0.0127
Brugia malayi Calcium binding EGF domain containing protein 0.0419 0.0735 0.0728
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Echinococcus granulosus dual specificity 0.0252 0.0321 0.0321
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0323 0.0498 0.047
Schistosoma mansoni protein kinase 0.0896 0.1922 0.1915
Echinococcus multilocularis glutamate synthase 0.0381 0.0642 0.0642
Entamoeba histolytica protein kinase, putative 0.0136 0.0031 0.0048
Trichomonas vaginalis glutathione reductase, putative 0.1435 0.3265 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0173 0.0124 0.0124
Schistosoma mansoni notch 0.0419 0.0735 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0671 0.1363 0.1356
Schistosoma mansoni hypothetical protein 0.0225 0.0254 0.0246
Schistosoma mansoni cell adhesion molecule 0.0979 0.213 0.2124
Echinococcus granulosus tyrosine protein kinase Srms 0.0557 0.1079 0.1079
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0961 0.2084 0.2084
Echinococcus multilocularis raf serine:threonine protein kinase 0.0153 0.0075 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0123 0.0308
Echinococcus multilocularis cyclin dependent kinase 5 0.0245 0.0303 0.0303
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0168 0.0112 0.0112
Echinococcus granulosus serine:threonine kinase SAD 1 0.0161 0.0094 0.0094
Echinococcus granulosus casein kinase I alpha 0.0224 0.0251 0.0251
Echinococcus multilocularis protein tyrosine kinase 0.0591 0.1164 0.1164
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0124 0.0116
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0688 0.1405 0.1398
Trichomonas vaginalis AGC family protein kinase 0.0353 0.0572 0.1694
Brugia malayi Calcium binding EGF domain containing protein 0.0419 0.0735 0.0728
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.1054 0.2317 0.2311
Brugia malayi Fes/CIP4 homology domain containing protein 0.0211 0.0219 0.0211
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus tyrosine protein kinase Fyn 0.0315 0.0476 0.0476
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1435 0.3265 0.3265
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0766 0.1599 0.1599
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1435 0.3265 1
Echinococcus granulosus protein kinase shaggy 0.0265 0.0354 0.0354
Giardia lamblia Kinase, AGC PKA 0.0233 0.0274 0.0504
Schistosoma mansoni notch 0.0419 0.0735 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0187 0.0158 0.015
Echinococcus multilocularis cyclin dependent kinase 19 0.1043 0.2289 0.2289
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0536 0.3201
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0354 0.2062
Entamoeba histolytica thioredoxin reductase, putative 0.0381 0.0642 0.3858
Echinococcus multilocularis Immunoglobulin 0.0225 0.0254 0.0254
Echinococcus granulosus protein jagged 2 0.0419 0.0735 0.0735
Trypanosoma cruzi hypothetical protein, conserved 0.0381 0.0642 0.0615
Echinococcus granulosus tyrosine protein kinase Lyn 0.0382 0.0645 0.0645
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0419 0.0735 0.3753
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Echinococcus granulosus serine:threonine protein kinase N2 0.06 0.1186 0.1186
Brugia malayi EGF-like domain containing protein 0.0419 0.0735 0.0728
Echinococcus granulosus glutamate synthase 0.0381 0.0642 0.0642
Plasmodium falciparum calcium-dependent protein kinase 4 0.0208 0.0211 0.0183
Trypanosoma cruzi NADH dehydrogenase, putative 0.0381 0.0642 0.0615
Echinococcus multilocularis dual specificity 0.0287 0.0407 0.0407
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0381 0.0642 0.0615
Echinococcus granulosus casein kinase I alpha 0.0224 0.0251 0.0251
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0173 0.0123 0.0095
Loa Loa (eye worm) protein kinase domain-containing protein 0.044 0.0788 0.0781
Brugia malayi serine/threonine protein kinase 6 0.0242 0.0296 0.0288
Echinococcus granulosus C type lectin domian containing protein 0.0773 0.1617 0.1617
Echinococcus granulosus Protein kinase C brain isozyme 0.0503 0.0945 0.0945
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0353 0.0572 0.0565
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0381 0.0642 0.0615
Echinococcus multilocularis protein jagged 2 0.0419 0.0735 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.0834 0.0827
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0274 0.0266
Echinococcus multilocularis neurogenic locus notch protein 4 0.0419 0.0735 0.0735
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0242 0.0296 0.0296
Brugia malayi hypothetical protein 0.0135 0.0029 0.0021
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0187 0.0158 0.0158
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0381 0.0642 0.3858
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0232 0.0272 0.0264
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0316 0.048 0.0472
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0254 0.0325 0.0325
Echinococcus granulosus twitchin 0.099 0.2156 0.2156
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0328 0.051 0.0483
Schistosoma mansoni nephrin 0.0941 0.2034 0.2028
Entamoeba histolytica protein kinase domain containing protein 0.0265 0.0354 0.2062
Schistosoma mansoni notch 0.0419 0.0735 0.0728
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0265 0.0354 0.0326
Echinococcus multilocularis titin 0.0187 0.0158 0.0158
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Loa Loa (eye worm) AGC/NDR protein kinase 0.0332 0.052 0.0512
Brugia malayi Muscle positioning protein 4 0.0419 0.0735 0.0728
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0456 0.0828 0.0828
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1435 0.3265 0.3246
Toxoplasma gondii selenide, water dikinase 0.0381 0.0642 0.0615
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0381 0.0642 0.0615
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0328 0.051 0.0483
Plasmodium vivax thioredoxin reductase, putative 0.4142 1 1
Echinococcus granulosus casein kinase I gamma 0.044 0.0788 0.0788
Brugia malayi basement membrane proteoglycan precursor 0.0225 0.0254 0.0246
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0206 0.0207 0.0099
Echinococcus multilocularis calcium dependent protein kinase 0.014 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0225 0.0254 0.0246
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Echinococcus multilocularis 0.0187 0.0158 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0321 0.0313
Brugia malayi Protein kinase domain containing protein 0.0315 0.0478 0.047
Schistosoma mansoni hypothetical protein 0.0187 0.0158 0.015
Trichomonas vaginalis AGC family protein kinase 0.034 0.054 0.1594
Echinococcus granulosus tyrosine protein kinase Fyn 0.0315 0.0476 0.0476
Echinococcus granulosus neurogenic locus protein delta 0.0419 0.0735 0.0735
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0328 0.051 0.0503
Leishmania major protein kinase, putative 0.0317 0.0482 0.0455
Echinococcus granulosus protein kinase C gamma type 0.0416 0.073 0.073
Echinococcus granulosus calcium activated potassium channel 0.0278 0.0386 0.0386
Entamoeba histolytica protein kinase , putative 0.0242 0.0296 0.1702
Schistosoma mansoni slit 0.0419 0.0736 0.0729
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0412 0.0718 0.0711
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0298 0.0436 0.0436
Echinococcus granulosus epidermal growth factor receptor 0.0497 0.093 0.093
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0161 0.0094 0.0066
Leishmania major protein kinase A catalytic subunit isoform 2 0.0233 0.0274 0.0245
Echinococcus multilocularis PAK box P21 Rho binding 0.0132 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0303 0.0295
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus cGMP dependent protein kinase 1 0.0173 0.0124 0.0124
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0225 0.0254 0.0254
Schistosoma mansoni tyrosine kinase 0.043 0.0764 0.0756
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0381 0.0642 0.0538
Echinococcus granulosus tyrosine protein kinase shark 0.0356 0.0579 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0326 0.0319
Echinococcus multilocularis mitogen activated protein kinase 3 0.0173 0.0123 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1183
Echinococcus granulosus ephrin type A receptor 4 A 0.0199 0.0189 0.0189
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Plasmodium falciparum casein kinase 2, alpha subunit 0.0206 0.0207 0.0179
Onchocerca volvulus 0.0773 0.1617 0.8367
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Schistosoma mansoni protein kinase 0.0224 0.0251 0.0243
Loa Loa (eye worm) hypothetical protein 0.1147 0.2548 0.2542
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0265 0.0354 0.0354
Brugia malayi hypothetical protein 0.0458 0.0834 0.0827
Echinococcus granulosus NDR protein kinase 0.0332 0.052 0.052
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0323 0.0498 0.0498
Echinococcus multilocularis lachesin 0.0412 0.0718 0.0718
Plasmodium falciparum thioredoxin reductase 0.4142 1 1
Brugia malayi EGF-like domain containing protein 0.0419 0.0735 0.0728
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0233 0.0274 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.012 0.0112
Schistosoma mansoni septate junction protein 0.0419 0.0735 0.0728
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.0803 0.0803
Echinococcus granulosus cyclin dependent kinase 5 0.0245 0.0303 0.0303
Brugia malayi SH2 domain containing protein 0.0449 0.0811 0.0803
Loa Loa (eye worm) hypothetical protein 0.0735 0.1523 0.1516
Onchocerca volvulus 0.0187 0.0158 0.0731
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0381 0.0642 0.3858
Trichomonas vaginalis AGC family protein kinase 0.0353 0.0572 0.1694
Brugia malayi basement membrane proteoglycan 0.0225 0.0254 0.0246
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0506 0.0952 0.0952
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0381 0.0642 0.0615
Loa Loa (eye worm) hypothetical protein 0.1147 0.2548 0.2542
Loa Loa (eye worm) AGC/AKT protein kinase 0.0603 0.1194 0.1187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0718 0.0711
Brugia malayi Immunoglobulin domain containing protein 0.0225 0.0254 0.0246
Schistosoma mansoni titin 0.0273 0.0373 0.0365
Echinococcus multilocularis protein jagged 1 0.0419 0.0735 0.0735
Echinococcus granulosus protein jagged 1 0.0419 0.0735 0.0735
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0354 0.102
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0268 0.026
Loa Loa (eye worm) TK/ROR protein kinase 0.0254 0.0325 0.0317
Echinococcus granulosus CDC7 cell division cycle 7 0.0185 0.0154 0.0154
Brugia malayi protein kinase C3,putative 0.0325 0.0503 0.0495
Brugia malayi Protein kinase domain containing protein 0.0171 0.012 0.0112
Brugia malayi Protein kinase domain containing protein 0.0655 0.1323 0.1316
Giardia lamblia Kinase, CMGC CK2 0.0206 0.0207 0.0293
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0224 0.0251 0.0243
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0479 0.0885 0.0878
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0506 0.0952 0.0952
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.0284 0.0804
Entamoeba histolytica protein kinase, putative 0.0171 0.012 0.0602
Plasmodium falciparum casein kinase 1 0.0224 0.0251 0.0223
Entamoeba histolytica PH domain containing protein kinase, putative 0.0249 0.0312 0.1803
Loa Loa (eye worm) hypothetical protein 0.021 0.0217 0.0209
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0245 0.0303 0.0303
Loa Loa (eye worm) hypothetical protein 0.0184 0.0152 0.0144
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0497 0.093 0.093
Brugia malayi ephrin receptor 1 precursor 0.0129 0.0015 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Loa Loa (eye worm) TK protein kinase 0.0381 0.0642 0.0634
Brugia malayi Immunoglobulin domain containing protein 0.0225 0.0254 0.0246
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0265 0.0354 0.0326
Echinococcus granulosus hypothetical protein 0.0249 0.0314 0.0314
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0414 0.0724 0.0717
Schistosoma mansoni ephrin receptor 0.0199 0.0189 0.0181
Onchocerca volvulus 0.0419 0.0735 0.3753
Entamoeba histolytica protein kinase domain containing protein 0.0206 0.0207 0.1147
Onchocerca volvulus Peroxidasin homolog 0.0187 0.0158 0.0731
Schistosoma mansoni slit 0.0187 0.0159 0.0151
Echinococcus multilocularis hypothetical protein 0.021 0.0217 0.0217
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0235 0.0279 0.0271
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1081 0.3263
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0328 0.051 0.0483
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0412 0.0718 0.3666
Trypanosoma brucei cdc2-related kinase 1 0.0245 0.0303 0.0275
Trypanosoma brucei protein kinase, putative 0.0181 0.0144 0.0115
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0296 0.0842
Echinococcus multilocularis serine:threonine protein kinase N2 0.0268 0.036 0.036
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0233 0.0274 0.0166
Schistosoma mansoni hypothetical protein 0.0225 0.0254 0.0246
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0317 0.0482 0.0455
Echinococcus granulosus tyrosine protein kinase Src42A 0.0191 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1435 0.3265 0.3265
Schistosoma mansoni serine/threonine protein kinase 0.0332 0.052 0.0512
Schistosoma mansoni hypothetical protein 0.0225 0.0254 0.0246
Onchocerca volvulus 0.0135 0.0029 0.0057
Echinococcus granulosus nephrin 0.0205 0.0204 0.0204
Echinococcus granulosus c-Jun N-terminal kinases 0.0545 0.105 0.105
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0558 0.1081 0.1081
Echinococcus granulosus defective proboscis extension response 0.0735 0.1523 0.1523
Brugia malayi Protein kinase domain containing protein 0.0655 0.1323 0.1316
Onchocerca volvulus 0.0135 0.0029 0.0057
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1435 0.3265 0.3246
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0637 0.1278 0.1278
Echinococcus multilocularis c src tyrosine kinase 0.0193 0.0175 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Plasmodium vivax unspecified product 0.0206 0.0207 0.0099
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1435 0.3265 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0728 0.1504 0.1497
Schistosoma mansoni serine/threonine protein kinase 0.0506 0.0952 0.0944
Toxoplasma gondii AGC kinase 0.0233 0.0274 0.0245
Schistosoma mansoni laminin gamma-3 chain 0.0419 0.0735 0.0728
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0208 0.0211 0.0103
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0135 0.0029 0.0029
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0735 0.1523 0.1516
Loa Loa (eye worm) hypothetical protein 0.0287 0.0407 0.0399
Schistosoma mansoni vesicular amine transporter 0.0735 0.1523 0.1516
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0225 0.0254 0.0246
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1081 0.3263
Schistosoma mansoni c4b-binding protein beta chain 0.0773 0.1617 0.161
Entamoeba histolytica PH domain containing protein kinase, putative 0.0339 0.0536 0.3201
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0242 0.0296 0.0296
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0245 0.0303 0.0295
Trichomonas vaginalis apoptosis inducing factor, putative 0.0381 0.0642 0.1907
Brugia malayi RhoGAP domain containing protein 0.0154 0.0077 0.0069
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0498 0.0934 0.0926
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0205 0.0204 0.0197
Echinococcus granulosus activin receptor type 0.0135 0.0029 0.0029
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0252 0.0321 0.0293
Brugia malayi Protein kinase domain containing protein 0.0414 0.0724 0.0717
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0237 0.0284 0.0284
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0339 0.0536 0.0509
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0233 0.0274 0.0245
Brugia malayi Protein kinase domain containing protein 0.0603 0.1194 0.1187
Entamoeba histolytica protein kinase, putative 0.0587 0.1155 0.706
Loa Loa (eye worm) hypothetical protein 0.0412 0.0718 0.0711
Loa Loa (eye worm) hypothetical protein 0.0412 0.0718 0.0711
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.1435 0.3265 0.3246
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0381 0.0642 0.0642
Brugia malayi Disorganized muscle protein 1 0.0187 0.0158 0.015
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0448 0.0808 0.08
Echinococcus multilocularis tyrosine protein kinase 0.0315 0.0478 0.0478
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0431 0.0765 0.0765
Trichomonas vaginalis CAMK family protein kinase 0.0448 0.0808 0.2419
Toxoplasma gondii casein kinase I 0.0224 0.0251 0.0223
Giardia lamblia Glutamate synthase 0.0381 0.0642 0.1672
Giardia lamblia Kinase, CMGC GSK 0.0265 0.0354 0.0759
Echinococcus granulosus leucine rich repeat containing protein 4 0.0187 0.0158 0.0158
Brugia malayi Fibronectin type III domain containing protein 0.0754 0.157 0.1563
Onchocerca volvulus 0.0185 0.0154 0.0711
Loa Loa (eye worm) hypothetical protein 0.0225 0.0254 0.0246
Echinococcus multilocularis serine threonine protein kinase 0.0416 0.073 0.073
Loa Loa (eye worm) hypothetical protein 0.0268 0.036 0.0352
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0414 0.0724 0.0724
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0177 0.0135 0.0135
Schistosoma mansoni serine/threonine protein kinase 0.06 0.1186 0.1179
Echinococcus granulosus casein kinase I delta 0.0224 0.0251 0.0251
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1081 0.3263
Echinococcus granulosus mitogen activated protein kinase 11 0.0328 0.051 0.051
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0374 0.0625 0.0625
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0718 0.0711
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0167 0.0109 0.0081
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0208 0.0211 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Onchocerca volvulus 0.0265 0.0354 0.1758
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0315 0.0476 0.0476
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0177 0.0135 0.0135
Echinococcus granulosus cGMP dependent protein kinase 0.0173 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0265 0.0354 0.0354
Giardia lamblia Kinase, CMGC MAPK 0.0173 0.0123 0.0026
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0381 0.0642 0.3858
Trypanosoma cruzi casein kinase, putative 0.0224 0.0251 0.0223
Trypanosoma cruzi cdc2-related kinase 1 0.0245 0.0303 0.0275
Plasmodium falciparum apical sushi protein 0.0773 0.1617 0.1592
Loa Loa (eye worm) TK/ABL protein kinase 0.0135 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0397 0.0681 0.0674
Brugia malayi Protein kinase domain containing protein 0.1043 0.2289 0.2283
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0896 0.1922 0.1922
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Echinococcus granulosus Immunoglobulin 0.0225 0.0254 0.0254
Schistosoma mansoni hypothetical protein 0.021 0.0217 0.0209
Loa Loa (eye worm) gastrulation defective protein 1 0.0975 0.2121 0.2114
Onchocerca volvulus 0.0603 0.1195 0.6158
Entamoeba histolytica protein kinase 2, putative 0.0323 0.0498 0.2958
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0237 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0171 0.012 0.0091
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0094 0.0086
Plasmodium falciparum protein kinase 5 0.0245 0.0303 0.0275
Schistosoma mansoni hypothetical protein 0.0187 0.0158 0.015
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Onchocerca volvulus Serine\/threonine kinase homolog 0.0558 0.1081 0.5565
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0265 0.0354 0.0346
Brugia malayi hypothetical protein 0.0225 0.0254 0.0246
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0208 0.0211 0.0211
Loa Loa (eye worm) CDC7 protein kinase 0.0185 0.0154 0.0146
Brugia malayi Heparan sulfate 0.0225 0.0254 0.0246
Echinococcus multilocularis tyrosine protein kinase HCK 0.0188 0.0162 0.0162
Echinococcus granulosus serine threonine protein kinase nrc 0.0323 0.0498 0.0498
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0165 0.0105 0.0105
Onchocerca volvulus 0.0205 0.0204 0.0975
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Trichomonas vaginalis glutamate synthase, putative 0.0381 0.0642 0.1907
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0315 0.0476 0.0476
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0244 0.0301 0.0301
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0205 0.0204 0.0197
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0208 0.0211 0.0211
Schistosoma mansoni septate junction protein 0.0225 0.0254 0.0246
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0225 0.0254 0.0246
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0161 0.0094 0.0066
Leishmania major hypothetical protein, conserved 0.0381 0.0642 0.0615
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0773 0.1617 0.161
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0176 0.0132 0.0124
Entamoeba histolytica protein kinase domain containing protein 0.0135 0.0029 0.0034
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0208 0.0211 0.0183
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0287 0.0407 0.0399
Trypanosoma cruzi NADH dehydrogenase, putative 0.0381 0.0642 0.0615
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0381 0.0642 0.0615
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0479 0.0885 0.0885
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0338 0.0536 0.0536
Echinococcus multilocularis expressed protein 0.0171 0.012 0.012
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0814 0.1718 0.1718
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0342 0.0983
Schistosoma mansoni hypothetical protein 0.0231 0.0268 0.026
Plasmodium falciparum glutathione reductase 0.4142 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0503 0.0945 0.0937
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0296 0.0288
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.0803 0.0803
Echinococcus multilocularis Glutaredoxin protein 5 0.0255 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0754 0.157 0.1563
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0637 0.1278 0.1278
Echinococcus granulosus tyrosine protein kinase Src42A 0.0315 0.0476 0.0476
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0173 0.0123 0.0095
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0446 0.0803 0.0803
Brugia malayi STE20-like kinase MST 0.053 0.1012 0.1005
Echinococcus multilocularis Immunoglobulin 0.0735 0.1523 0.1523
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.0251 0.0243
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.4142 1 1
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0414 0.0724 0.0724
Echinococcus granulosus neural cadherin 0.0419 0.0735 0.0735
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0187 0.0158 0.0158
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1081 0.3263
Brugia malayi Variant SH3 domain containing protein 0.0154 0.0077 0.0069
Giardia lamblia Kinase, CDC7 0.0185 0.0154 0.0124
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0896 0.1922 0.1922
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1183
Brugia malayi EGF-like domain containing protein 0.0419 0.0735 0.0728
Giardia lamblia Kinase, PLK 0.0558 0.1081 0.3068
Entamoeba histolytica protein kinase, putative 0.0265 0.0354 0.2062
Brugia malayi Immunoglobulin I-set domain containing protein 0.0225 0.0254 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0503 0.0945 0.0937
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0728 0.1504 0.1504
Onchocerca volvulus 0.0187 0.0158 0.0731
Onchocerca volvulus 0.0419 0.0735 0.3753
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0171 0.012 0.0091
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0268 0.024
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0265 0.0354 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0094 0.0086
Schistosoma mansoni tyrosine kinase 0.0132 0.0021 0.0013
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0311 0.0468 0.046
Echinococcus granulosus neurogenic locus notch protein 0.0419 0.0735 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0124 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0274 0.0266
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.0803 0.0795
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0123 0.0308
Loa Loa (eye worm) disorganized muscle protein 1 0.0187 0.0158 0.015
Brugia malayi EGF-like domain containing protein 0.0419 0.0735 0.0728
Brugia malayi casein kinase I 0.0224 0.0251 0.0243
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0174 0.0128 0.0652
Loa Loa (eye worm) hypothetical protein 0.0412 0.0718 0.0711
Echinococcus multilocularis hemicentin 1 0.0412 0.0718 0.0718
Brugia malayi Prion-like- 0.0412 0.0718 0.0711
Echinococcus multilocularis neuroglian 0.0431 0.0765 0.0765
Schistosoma mansoni protein kinase 0.0135 0.0029 0.0021
Onchocerca volvulus 0.0381 0.0642 0.3264
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Echinococcus multilocularis notch 0.0419 0.0735 0.0735
Trypanosoma cruzi hypothetical protein, conserved 0.0381 0.0642 0.0615
Loa Loa (eye worm) TK/FAK protein kinase 0.0597 0.118 0.1172
Schistosoma mansoni glutamate synthase 0.0381 0.0642 0.0634
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0242 0.0296 0.1702
Loa Loa (eye worm) hypothetical protein 0.0161 0.0094 0.0086
Trichomonas vaginalis glutamate synthase, putative 0.0381 0.0642 0.1907
Loa Loa (eye worm) hypothetical protein 0.0754 0.157 0.1563
Echinococcus granulosus tyrosine protein kinase Fyn 0.0315 0.0476 0.0476
Echinococcus multilocularis titin 0.0187 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0205 0.0204 0.0197
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0315 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0332 0.052 0.052
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0177 0.0135 0.0135
Toxoplasma gondii EGF family domain-containing protein 0.0419 0.0735 0.0708
Onchocerca volvulus 0.0135 0.0029 0.0057
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0174 0.0128 0.0652
Brugia malayi C1-like domain containing protein 0.0449 0.0811 0.0803
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0386 0.0378
Brugia malayi Protein kinase domain containing protein 0.0252 0.0321 0.0313
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0431 0.0765 0.0765
Echinococcus granulosus neurogenic locus notch protein 4 0.0419 0.0735 0.0735
Echinococcus multilocularis titin 0.0187 0.0158 0.0158
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0287 0.0407 0.0379
Trypanosoma brucei cdc2-related kinase 3 0.0245 0.0303 0.0275
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0287 0.0407 0.0399
Trypanosoma cruzi cdc2-related kinase 3 0.0245 0.0303 0.0275
Echinococcus granulosus neuroglian 0.0431 0.0765 0.0765
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0315 0.0476 0.0476
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0208 0.0211 0.0203
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0233 0.0274 0.0245
Schistosoma mansoni hypothetical protein 0.0381 0.0642 0.0634
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0161 0.0094 0.0066
Toxoplasma gondii rhoptry neck protein RON9 0.0773 0.1617 0.1592
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0161 0.0094 0.0066
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0332 0.052 0.052
Onchocerca volvulus 0.0671 0.1363 0.704
Echinococcus granulosus cGMP dependent protein kinase 1 0.0173 0.0124 0.0124
Plasmodium falciparum serine/threonine protein kinase 0.0171 0.012 0.0091
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0469 0.0862 0.0862
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0381 0.0642 0.3858
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1435 0.3265 0.3246
Leishmania major casein kinase II, putative 0.0206 0.0207 0.0179
Brugia malayi SRC-1 0.0315 0.0476 0.0469
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Trichomonas vaginalis STE family protein kinase 0.0281 0.0392 0.1138
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0165 0.0105 0.0105
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0187 0.0159 0.0159
Echinococcus granulosus Immunoglobulin 0.0225 0.0254 0.0254
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0285 0.0404 0.1174
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0231 0.0268 0.026
Onchocerca volvulus Netrin receptor homolog 0.0246 0.0306 0.1509
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0718 0.0711
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0381 0.0642 0.0642
Plasmodium vivax glycogen synthase kinase 3, putative 0.0265 0.0354 0.0248
Brugia malayi EGF-like domain containing protein 0.0419 0.0735 0.0728
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0431 0.0765 0.0765
Echinococcus multilocularis growth factor receptor bound protein 2 0.0126 0.0008 0.0008
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0558 0.1081 0.1081
Echinococcus multilocularis N chimaerin 0.0154 0.0077 0.0077
Loa Loa (eye worm) TK protein kinase 0.0315 0.0478 0.047
Leishmania major hypothetical protein, conserved 0.0381 0.0642 0.0615
Brugia malayi Protein kinase domain containing protein 0.1944 0.4532 0.4527
Echinococcus granulosus mitogen activated protein kinase 3 0.0173 0.0123 0.0123
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0191 0.0169 0.0169
Schistosoma mansoni neuroglian 0.0431 0.0765 0.0757
Giardia lamblia Kinase, NEK 0.0281 0.0392 0.0881
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0075 0.0067
Echinococcus granulosus protein tyrosine kinase 0.0591 0.1164 0.1164
Trichomonas vaginalis CAMK family protein kinase 0.0237 0.0284 0.0804
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0193 0.0175 0.0167
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0558 0.1081 0.1074
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0296 0.0288
Onchocerca volvulus 0.0419 0.0735 0.3753
Brugia malayi Immunoglobulin I-set domain containing protein 0.0226 0.0256 0.0248
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0211 0.0203
Echinococcus granulosus serine:threonine protein kinase 0.0235 0.0279 0.0279
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0169 0.0115 0.0006
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0449 0.0811 0.0811
Trichomonas vaginalis CMGC family protein kinase 0.0287 0.0407 0.1183
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0381 0.0642 0.1907
Entamoeba histolytica serine/threonine protein kinase, putative 0.0558 0.1081 0.66
Schistosoma mansoni hypothetical protein 0.0187 0.0158 0.015
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0381 0.0642 0.0642
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.0296 0.1702
Onchocerca volvulus 0.0187 0.0158 0.0731
Brugia malayi Protein kinase domain containing protein 0.0317 0.0482 0.0475
Schistosoma mansoni serine/threonine-protein kinase 0.0339 0.0536 0.0529
Schistosoma mansoni cell adhesion molecule 0.0225 0.0254 0.0246
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0381 0.0642 0.0615
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0255 0.0329 0.0329
Onchocerca volvulus 0.0187 0.0158 0.0731
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0381 0.0642 0.0642
Onchocerca volvulus Peroxidasin homolog 0.0187 0.0159 0.0738
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0177 0.0135 0.0135
Brugia malayi Immunoglobulin domain containing protein 0.0225 0.0254 0.0246
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0255 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0245 0.0303 0.0295
Brugia malayi Leucine Rich Repeat family protein 0.0187 0.0159 0.0151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Entamoeba histolytica protein kinase, putative 0.0148 0.0062 0.0243
Echinococcus multilocularis insulin receptor 0.0618 0.1232 0.1232
Toxoplasma gondii thioredoxin reductase 0.4142 1 1
Trichomonas vaginalis CK1 family protein kinase 0.0224 0.0251 0.0702
Echinococcus granulosus aurora kinase A 0.0242 0.0296 0.0296
Schistosoma mansoni tyrosine kinase 0.0374 0.0625 0.0617
Loa Loa (eye worm) hypothetical protein 0.0412 0.0718 0.0711
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0757 0.1577 0.1577
Echinococcus multilocularis thioredoxin glutathione reductase 0.4142 1 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0244 0.0301 0.0293
Echinococcus granulosus tyrosine kinase 0.0135 0.0029 0.0029
Trypanosoma cruzi casein kinase, putative 0.0224 0.0251 0.0223
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0154 0.0077 0.0077
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0458 0.0834 0.0827
Brugia malayi Immunoglobulin I-set domain containing protein 0.0431 0.0765 0.0757
Echinococcus granulosus growth factor receptor bound protein 2 0.0128 0.0013 0.0013
Schistosoma mansoni titin 0.0205 0.0204 0.0197
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Onchocerca volvulus Slit protein homolog 0.0464 0.0849 0.4349
Loa Loa (eye worm) glutathione reductase 0.4142 1 1
Brugia malayi hypothetical protein 0.0231 0.0268 0.026
Schistosoma mansoni protein kinase 0.0896 0.1922 0.1915
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0204 0.0197
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.053 0.1012 0.1005
Echinococcus granulosus lachesin 0.0412 0.0718 0.0718
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0187 0.0158 0.015
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0315 0.0476 0.0476
Brugia malayi map kinase activated protein kinase protein 2 0.0814 0.1718 0.1711
Leishmania major protein kinase, putative 0.0208 0.0211 0.0183
Onchocerca volvulus 0.0205 0.0204 0.0975
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0233 0.0274 0.0245
Echinococcus multilocularis casein kinase i 0.0224 0.0251 0.0251
Brugia malayi Protein kinase domain 0.0177 0.0135 0.0127
Brugia malayi Prion-like- 0.0187 0.0158 0.015
Plasmodium falciparum ferrodoxin reductase-like protein 0.0381 0.0642 0.0615
Brugia malayi intracellular kinase 0.0265 0.0354 0.0346
Brugia malayi kettin 0.0187 0.0158 0.015
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0208 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0225 0.0254 0.0254
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0204 0.0197
Onchocerca volvulus 0.0773 0.1617 0.8367
Echinococcus granulosus neurogenic locus notch protein 0.0419 0.0735 0.0735
Plasmodium falciparum protein serine/threonine kinase-1 0.0317 0.0482 0.0455
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0173 0.0123 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Echinococcus multilocularis cyclin dependent kinase 1 0.0245 0.0303 0.0303
Trypanosoma cruzi casein kinase II, putative 0.0206 0.0207 0.0179
Loa Loa (eye worm) SRC-1 0.0315 0.0476 0.0469
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0296 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0386 0.0378
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0265 0.0354 0.0326
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.4142 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0252 0.0321 0.0293
Echinococcus multilocularis Immunoglobulin 0.0735 0.1523 0.1523
Echinococcus multilocularis myosin iiia 0.0174 0.0128 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0485 0.09 0.0893
Onchocerca volvulus 0.0224 0.0251 0.1219
Echinococcus multilocularis neurogenic locus protein delta 0.0419 0.0735 0.0735
Echinococcus granulosus hemicentin 1 0.0412 0.0718 0.0718
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0161 0.0094 0.0086
Schistosoma mansoni kinase 0.0596 0.1176 0.1169
Echinococcus granulosus contactin 0.0431 0.0765 0.0765
Loa Loa (eye worm) AGC/PKA protein kinase 0.0233 0.0274 0.0266
Schistosoma mansoni titin 0.0187 0.0158 0.015
Schistosoma mansoni tyrosine kinase 0.0356 0.0579 0.0571
Echinococcus granulosus peroxidasin 0.0412 0.072 0.072
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Echinococcus multilocularis tyrosine protein kinase otk 0.0412 0.0718 0.0718
Brugia malayi Calcium binding EGF domain containing protein 0.0419 0.0735 0.0728
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0241 0.0294 0.0286
Brugia malayi Protein kinase domain containing protein 0.04 0.0688 0.0681
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0208 0.0211 0.0103
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0381 0.0642 0.1907
Echinococcus granulosus Glutaredoxin protein 5 0.0255 0.0329 0.0329
Brugia malayi serine/threonine-protein kinase PAK 7 0.0479 0.0885 0.0878
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0261 0.0343 0.0335
Echinococcus multilocularis serine:threonine protein kinase 3 0.053 0.1012 0.1012
Echinococcus multilocularis fibropellin Ia 0.0419 0.0735 0.0735
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0374 0.0625 0.0625
Onchocerca volvulus 0.0773 0.1617 0.8367
Schistosoma mansoni serine/threonine kinase 0.0456 0.0828 0.0821
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0317 0.0482 0.0455
Onchocerca volvulus 0.0231 0.0268 0.1306
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0735 0.1523 0.1523
Echinococcus granulosus c src tyrosine kinase 0.0193 0.0175 0.0175
Echinococcus multilocularis protein jagged 1 0.0419 0.0735 0.0735
Brugia malayi Animal haem peroxidase family protein 0.0187 0.0158 0.015
Echinococcus multilocularis nervana 2 0.0255 0.0329 0.0329
Schistosoma mansoni notch 0.0419 0.0735 0.0728
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0225 0.0254 0.0254
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0174 0.0128 0.0099
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0485 0.09 0.09
Schistosoma mansoni glutamate synthase 0.0381 0.0642 0.0634
Schistosoma mansoni protein kinase 0.0177 0.0135 0.0127
Echinococcus multilocularis mitogen activated protein kinase 11 0.0328 0.051 0.051
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0503 0.0945 0.0945
Brugia malayi Protein kinase domain containing protein 0.0353 0.0572 0.0565
Loa Loa (eye worm) AUR protein kinase 0.0242 0.0296 0.0288
Loa Loa (eye worm) casein kinase 0.0372 0.062 0.0612
Brugia malayi hypothetical protein 0.0754 0.157 0.1563
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0381 0.0642 0.0615
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0418 0.0734 0.0734
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Onchocerca volvulus 0.0156 0.0083 0.0337
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0187 0.0158 0.0158
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0315 0.0476 0.0476
Loa Loa (eye worm) hypothetical protein 0.0961 0.2084 0.2077
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0154 0.0077 0.0069
Brugia malayi Protein kinase domain containing protein 0.0135 0.0029 0.0021
Loa Loa (eye worm) AGC/PKA protein kinase 0.0233 0.0274 0.0266
Echinococcus multilocularis CDC7 cell division cycle 7 0.0185 0.0154 0.0154
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1435 0.3265 0.2803
Schistosoma mansoni protein kinase 0.0547 0.1054 0.1046
Echinococcus granulosus titin 0.0273 0.0373 0.0373
Giardia lamblia Thioredoxin reductase 0.0381 0.0642 0.1672
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0315 0.0476 0.0476
Trichomonas vaginalis STE family protein kinase 0.0177 0.0135 0.0344
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0173 0.0123 0.0095
Toxoplasma gondii AGC kinase 0.0587 0.1155 0.1129
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0381 0.0642 0.0615
Brugia malayi Immunoglobulin I-set domain containing protein 0.1672 0.3854 0.3849
Plasmodium falciparum glutathione reductase 0.1435 0.3265 0.3246
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1435 0.3265 1
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0338 0.0536 0.0528
Echinococcus multilocularis ephrin type A receptor 4 A 0.0199 0.0189 0.0189
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0728 0.1504 0.1504
Onchocerca volvulus 0.0287 0.0407 0.2033
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0412 0.0718 0.0711
Echinococcus granulosus expressed protein 0.0171 0.012 0.012
Echinococcus granulosus fibroblast growth factor receptor 4 0.0374 0.0625 0.0625
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0171 0.012 0.0091
Brugia malayi protein kinase C II. 0.0421 0.0741 0.0734
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Echinococcus multilocularis protein kinase c epsilon type 0.0421 0.0741 0.0741
Entamoeba histolytica protein kinase, putative 0.0252 0.0321 0.1856
Loa Loa (eye worm) hypothetical protein 0.0382 0.0644 0.0636
Echinococcus multilocularis activin receptor type 0.0135 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0135 0.0029 0.0021
Loa Loa (eye worm) hypothetical protein 0.0225 0.0254 0.0246
Onchocerca volvulus Putative cubilin 0.0419 0.0735 0.3753
Plasmodium vivax serine/threonine kinase-1, putative 0.0317 0.0482 0.0377
Brugia malayi probable protein kinase 0.0547 0.1054 0.1046
Giardia lamblia Kinase, NEK 0.0281 0.0392 0.0881
Brugia malayi Doublecortin family protein 0.0311 0.0468 0.046
Loa Loa (eye worm) hypothetical protein 0.0225 0.0254 0.0246
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0545 0.105 0.1043
Schistosoma mansoni disulfide oxidoreductase 0.0381 0.0642 0.0634
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0338 0.0534 0.0527
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0231 0.0268 0.0268
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0728 0.1504 0.1497
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0242 0.0296 0.0189
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0315 0.0476 0.0476
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0381 0.0642 0.1907
Loa Loa (eye worm) hypothetical protein 0.0412 0.0718 0.0711
Leishmania major trypanothione reductase 0.4142 1 1
Echinococcus granulosus casein kinase I delta 0.0224 0.0251 0.0251
Schistosoma mansoni cell adhesion molecule 0.0412 0.0718 0.0711
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Brugia malayi Cadherin domain containing protein 0.0419 0.0735 0.0728
Loa Loa (eye worm) AGC/PKN protein kinase 0.06 0.1186 0.1179
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0688 0.1405 0.1398
Trichomonas vaginalis AGC family protein kinase 0.0233 0.0274 0.0772
Echinococcus granulosus casein kinase ii subunit alpha 0.0206 0.0207 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.1043 0.2289 0.2283
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0545 0.105 0.105
Plasmodium vivax calcium-dependent protein kinase, putative 0.0208 0.0211 0.0103
Brugia malayi Immunoglobulin I-set domain containing protein 0.0244 0.0301 0.0293
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0187 0.0158 0.015
Echinococcus granulosus protein jagged 1 0.0419 0.0735 0.0735
Echinococcus granulosus epidermal growth factor receptor 0.0712 0.1466 0.1466
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0208 0.0211 0.0211
Trypanosoma brucei Casein kinase II 0.0206 0.0207 0.0179
Entamoeba histolytica protein kinase domain containing protein 0.0252 0.0321 0.1856
Echinococcus multilocularis serine:threonine protein kinase 0.0235 0.0279 0.0279
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0381 0.0642 0.0642
Schistosoma mansoni hypothetical protein 0.0205 0.0204 0.0197
Trypanosoma cruzi cdc2-related kinase 3 0.0245 0.0303 0.0275
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0412 0.0718 0.0711
Entamoeba histolytica casein kinase 1, putative 0.0224 0.0251 0.1421
Echinococcus multilocularis casein kinase I delta 0.0224 0.0251 0.0251
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0317 0.0482 0.0455
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0381 0.0642 0.0642
Onchocerca volvulus 0.0419 0.0735 0.3753
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0299 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.0412 0.072 0.0712
Onchocerca volvulus 0.0187 0.0158 0.0731
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0167 0.0109 0.0081
Schistosoma mansoni myosin-binding protein-related 0.0205 0.0204 0.0197
Plasmodium vivax protein kinase Crk2 0.0245 0.0303 0.0196
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0187 0.0158 0.015
Brugia malayi Immunoglobulin I-set domain containing protein 0.0273 0.0373 0.0365
Entamoeba histolytica casein kinase, putative 0.0206 0.0207 0.1147
Entamoeba histolytica protein kinase, putative 0.0287 0.0407 0.2392
Entamoeba histolytica cyclin C, putative 0.0777 0.1626 1
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0458 0.0834 0.0834
Loa Loa (eye worm) hypothetical protein 0.0235 0.0279 0.0271
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0303 0.0295
Loa Loa (eye worm) hypothetical protein 0.0205 0.0204 0.0197
Brugia malayi Temporarily assigned gene name protein 59 0.0231 0.0268 0.026
Echinococcus multilocularis c4b binding protein beta chain 0.0773 0.1617 0.1617
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0112 0.0272
Onchocerca volvulus 0.0773 0.1617 0.8367
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0261 0.0343 0.0343
Echinococcus multilocularis serine:threonine protein kinase 0.0235 0.0279 0.0279
Brugia malayi Protein kinase domain containing protein 0.0245 0.0303 0.0295
Schistosoma mansoni serine/threonine protein kinase 0.0526 0.1003 0.0996
Loa Loa (eye worm) hypothetical protein 0.0248 0.0311 0.0304
Onchocerca volvulus 0.0185 0.0154 0.0711
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Echinococcus multilocularis serine:threonine protein kinase N2 0.0332 0.052 0.052
Schistosoma mansoni serine/threonine protein kinase 0.0814 0.1718 0.1711
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Brugia malayi glutamate synthase 0.0381 0.0642 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Schistosoma mansoni cell adhesion molecule 0.0205 0.0204 0.0197
Brugia malayi Stress-activated protein kinase jnk-1 0.0545 0.105 0.1043
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0317 0.0482 0.0455
Onchocerca volvulus Serine\/threonine kinase homolog 0.0338 0.0536 0.271
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1435 0.3265 0.326
Schistosoma mansoni serine/threonine protein kinase 0.0414 0.0724 0.0717
Onchocerca volvulus 0.0397 0.0681 0.3471
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0431 0.0765 0.0757
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0381 0.0642 0.0634
Schistosoma mansoni hypothetical protein 0.0187 0.0158 0.015
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0225 0.0254 0.0246
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1435 0.3265 1
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0233 0.0274 0.0245
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0242 0.0296 0.1702
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0273 0.0373 0.0365
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Treponema pallidum NADH oxidase 0.1435 0.3265 1
Entamoeba histolytica protein kinase, putative 0.0171 0.012 0.0602
Onchocerca volvulus 0.0187 0.0158 0.0731
Schistosoma mansoni septate junction protein 0.0225 0.0254 0.0246
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0381 0.0642 0.0538
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0303 0.0863
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0205 0.0204 0.0197
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0254 0.0325 0.0325
Echinococcus multilocularis netrin receptor unc 5 0.0285 0.0403 0.0403
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0173 0.0123 0.0115
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0381 0.0642 0.0634
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0298 0.0436 0.0436
Echinococcus multilocularis death associated protein kinase 1 0.0912 0.1963 0.1963
Echinococcus granulosus tyrosine protein kinase 0.0315 0.0478 0.0478
Echinococcus granulosus Vam6:Vps39 protein 0.0231 0.0268 0.0268
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0265 0.0354 0.0346
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0332 0.052 0.052
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0287 0.0407 0.0379
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1435 0.3265 0.3191
Echinococcus granulosus titin 0.0187 0.0158 0.0158
Echinococcus multilocularis C type lectin domian containing protein 0.0773 0.1617 0.1617
Loa Loa (eye worm) hypothetical protein 0.0225 0.0254 0.0246
Loa Loa (eye worm) hypothetical protein 0.0287 0.0407 0.0399
Schistosoma mansoni serine/threonine kinase 0.0332 0.052 0.0512
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0177 0.0135 0.0135
Echinococcus granulosus dual specificity protein kinase clk2 0.0317 0.0482 0.0482
Echinococcus multilocularis neurogenic locus protein delta 0.0419 0.0735 0.0735
Plasmodium falciparum calcium-dependent protein kinase 2 0.0208 0.0211 0.0183
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0338 0.0536 0.0536
Trichomonas vaginalis CAMK family protein kinase 0.0558 0.1081 0.3263
Schistosoma mansoni titin 0.0187 0.0158 0.015
Brugia malayi Protein kinase domain containing protein 0.0332 0.052 0.0512
Entamoeba histolytica disulphide oxidoreductase, putative 0.0381 0.0642 0.3858
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.1435 0.3265 0.3246
Loa Loa (eye worm) cyclin domain-containing protein 0.0766 0.1599 0.1592
Leishmania major protein kinase A catalytic subunit 0.0233 0.0274 0.0245
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Loa Loa (eye worm) hypothetical protein 0.0655 0.1323 0.1316
Echinococcus granulosus serine:threonine protein kinase 3 0.053 0.1012 0.1012
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0315 0.0476 0.0476
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Brugia malayi Cyclin, N-terminal domain containing protein 0.0766 0.1599 0.1592
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0381 0.0642 0.0642
Loa Loa (eye worm) hypothetical protein 0.0168 0.0112 0.0104
Loa Loa (eye worm) hypothetical protein 0.0223 0.0247 0.024
Entamoeba histolytica cell division protein kinase 2, putative 0.0253 0.0324 0.1874
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1435 0.3265 0.2803
Plasmodium falciparum NIMA related kinase 1 0.0281 0.0392 0.0365
Toxoplasma gondii aurora kinase 0.0242 0.0296 0.0268
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0156 0.0083 0.0054
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Echinococcus granulosus tyrosine protein kinase otk 0.0412 0.0718 0.0718
Trichomonas vaginalis mercuric reductase, putative 0.1435 0.3265 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0469 0.0862 0.0862
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0446 0.0803 0.0803
Schistosoma mansoni protein kinase 0.0177 0.0135 0.0127
Trichomonas vaginalis CMGC family protein kinase 0.0317 0.0482 0.1415
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0926 0.1997 0.1991
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0323 0.0498 0.0498
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1435 0.3265 0.3191
Plasmodium vivax serine/threonine protein kinase, putative 0.0171 0.012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Schistosoma mansoni rap gtpase-activating protein 0.0231 0.0268 0.026
Plasmodium vivax glutathione reductase, putative 0.4142 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0718 0.0711
Schistosoma mansoni protein kinase 0.0757 0.1577 0.157
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0431 0.0765 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0112 0.0104
Loa Loa (eye worm) hypothetical protein 0.086 0.1832 0.1826
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0381 0.0642 0.0615
Echinococcus granulosus netrin receptor unc 5 0.0285 0.0403 0.0403
Schistosoma mansoni tyrosine kinase 0.0315 0.0476 0.0469
Trypanosoma brucei polo-like protein kinase 0.0558 0.1081 0.1056
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0386 0.0378
Plasmodium falciparum cGMP-dependent protein kinase 0.0173 0.0124 0.0096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0754 0.157 0.1563
Plasmodium vivax ferrodoxin reductase, putative 0.0381 0.0642 0.0538
Entamoeba histolytica protein kinase, putative 0.0252 0.0321 0.1856
Entamoeba histolytica protein kinase, putative 0.0188 0.0162 0.0864
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Schistosoma mansoni notch 0.0419 0.0735 0.0728
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Schistosoma mansoni hypothetical protein 0.0187 0.0158 0.015
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0252 0.0321 0.0313
Entamoeba histolytica casein kinase, putative 0.0224 0.0251 0.1421
Echinococcus granulosus serine:threonine protein kinase 0.0235 0.0279 0.0279
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Trichomonas vaginalis CK1 family protein kinase 0.0224 0.0251 0.0702
Echinococcus multilocularis mitogen activated protein kinase 11 0.0328 0.051 0.051
Echinococcus multilocularis tyrosine protein kinase Abl 0.0193 0.0175 0.0175
Onchocerca volvulus 0.0273 0.0373 0.1857
Onchocerca volvulus 0.0773 0.1617 0.8367
Brugia malayi Protein kinase domain containing protein 0.0757 0.1577 0.157
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0381 0.0642 0.0642
Trichomonas vaginalis STE family protein kinase 0.0177 0.0135 0.0344
Echinococcus multilocularis Immunoglobulin 0.0225 0.0254 0.0254
Schistosoma mansoni serine/threonine protein kinase 0.0545 0.105 0.1043
Brugia malayi putative serine/threonine kinase SADA gamma 0.0161 0.0094 0.0086
Echinococcus multilocularis slit 2 protein 0.0464 0.0849 0.0849
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0173 0.0123 0.0095
Schistosoma mansoni hypothetical protein 0.021 0.0217 0.0209
Schistosoma mansoni netrin receptor unc5 0.0225 0.0254 0.0246
Brugia malayi pregnancy-associated plasma protein-A 0.0773 0.1617 0.161
Trichomonas vaginalis CMGC family protein kinase 0.0265 0.0354 0.102
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0381 0.0642 0.0615
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0317 0.0482 0.0455
Echinococcus multilocularis roundabout 2 0.0431 0.0765 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0421 0.0741 0.0734
Brugia malayi cell division control protein 2 homolog 0.0245 0.0303 0.0295
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0174 0.0128 0.0099
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Schistosoma mansoni cell polarity protein 0.0419 0.0735 0.0728
Schistosoma mansoni vav2 0.017 0.0116 0.0108
Echinococcus multilocularis cyclin 0.0766 0.1599 0.1599
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0224 0.0251 0.0223
Loa Loa (eye worm) hypothetical protein 0.0246 0.0305 0.0297
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0381 0.0642 0.0634
Trichomonas vaginalis CAMK family protein kinase 0.0261 0.0342 0.0983
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1043 0.2289 0.2283
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0381 0.0642 0.3858
Trichomonas vaginalis CMGC family protein kinase 0.0206 0.0207 0.0567
Trypanosoma brucei SNF1-related protein kinases, putative 0.0161 0.0094 0.0066
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1944 0.4532 0.4527
Giardia lamblia Kinase, CMGC CDK 0.0245 0.0303 0.0598
Trichomonas vaginalis STE family protein kinase 0.0177 0.0135 0.0344
Echinococcus granulosus mitogen activated protein kinase 14 0.0328 0.051 0.051
Schistosoma mansoni nephrin 0.0431 0.0765 0.0757
Echinococcus multilocularis peroxidasin 0.0412 0.072 0.072
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Schistosoma mansoni vam6/vps39 related 0.0231 0.0268 0.026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0187 0.0158 0.015
Echinococcus granulosus roundabout 2 0.0431 0.0765 0.0765
Brugia malayi phosphoinositide-dependent protein kinase I 0.0168 0.0112 0.0104
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0403 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0167 0.0159
Echinococcus granulosus casein kinase i 0.0224 0.0251 0.0251
Schistosoma mansoni titin 0.0412 0.0718 0.0711
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0208 0.0211 0.0183
Echinococcus granulosus serine:threonine protein kinase N2 0.0268 0.036 0.036
Schistosoma mansoni protein kinase 0.0242 0.0296 0.0288
Echinococcus granulosus protein kinase 0.0316 0.048 0.048
Trypanosoma cruzi casein kinase, putative 0.0224 0.0251 0.0223
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0168 0.0112 0.0104
Schistosoma mansoni protein kinase 0.0132 0.0023 0.0015
Brugia malayi notch-like transmembrane receptor 0.0419 0.0735 0.0728
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0381 0.0642 0.1907
Echinococcus multilocularis twitchin 0.0254 0.0326 0.0326
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0205 0.0204 0.0204
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1435 0.3265 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0185 0.0154 0.0146
Loa Loa (eye worm) hypothetical protein 0.0419 0.0735 0.0728
Toxoplasma gondii NADPH-glutathione reductase 0.1435 0.3265 0.3246
Brugia malayi SH2 domain containing protein 0.0135 0.0029 0.0021
Echinococcus multilocularis dual specificity protein kinase clk2 0.0317 0.0482 0.0482
Schistosoma mansoni protein kinase 0.0206 0.0207 0.0199
Entamoeba histolytica protein kinase, putative 0.0148 0.0062 0.0243
Trypanosoma cruzi casein kinase, putative 0.0224 0.0251 0.0223
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0456 0.0828 0.0828
Schistosoma mansoni hypothetical protein 0.0419 0.0735 0.0728
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0245 0.0303 0.0295
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0135 0.0029 0.0036
Echinococcus multilocularis 0.0249 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0431 0.0765 0.0757
Echinococcus multilocularis roundabout 2 0.1166 0.2595 0.2595
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0332 0.052 0.052
Loa Loa (eye worm) hypothetical protein 0.0295 0.0428 0.042
Brugia malayi Cadherin domain containing protein 0.0419 0.0735 0.0728
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0225 0.0254 0.0246
Trichomonas vaginalis STE family protein kinase 0.0174 0.0128 0.0322
Giardia lamblia Kinase, STE STE20 0.0174 0.0128 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0185 0.0154 0.0403
Echinococcus multilocularis hemicentin 1 0.0412 0.0718 0.0718
Echinococcus granulosus cyclin dependent kinase 0.0245 0.0303 0.0303
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0381 0.0642 0.1672
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0208 0.0211 0.0183
Brugia malayi MAP kinase sur-1 0.0173 0.0123 0.0115
Brugia malayi Cyclin C 0.1536 0.3515 0.3509
Echinococcus multilocularis fat cadherin tumor suppressor 0.0419 0.0735 0.0735
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0244 0.0301 0.0301
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0245 0.0303 0.0275
Brugia malayi Immunoglobulin I-set domain containing protein 0.0232 0.0272 0.0264
Trichomonas vaginalis CAMK family protein kinase 0.0566 0.1102 0.3327
Schistosoma mansoni cell adhesion molecule 0.0205 0.0204 0.0197
Brugia malayi GCC2 and GCC3 family protein 0.1191 0.2658 0.2652
Schistosoma mansoni serine/threonine protein kinase 0.0558 0.1081 0.1074
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0381 0.0642 0.1907
Trichomonas vaginalis AGC family protein kinase 0.0168 0.0112 0.0272
Loa Loa (eye worm) TK/FER protein kinase 0.0135 0.0029 0.0021
Trypanosoma brucei NADH dehydrogenase 0.0381 0.0642 0.0615
Echinococcus multilocularis tyrosine kinase 0.0135 0.0029 0.0029
Brugia malayi Protein kinase domain containing protein 0.0338 0.0536 0.0528
Brugia malayi hypothetical protein 0.0773 0.1617 0.161
Leishmania major protein kinase, putative 0.0242 0.0296 0.0268
Loa Loa (eye worm) hypothetical protein 0.0231 0.0268 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0446 0.0803 0.0795
Echinococcus multilocularis insulin growth factor binding 0.0187 0.0158 0.0158
Echinococcus multilocularis NCK adaptor protein 0.0128 0.0013 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0561 0.1089 0.1082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0412 0.0718 0.0711
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0296 0.0842
Entamoeba histolytica protein kinase, putative 0.0332 0.052 0.3097
Trypanosoma brucei rac serine-threonine kinase, putative 0.0603 0.1194 0.1168
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0317 0.0482 0.0455
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0398 0.0683 0.0676
Trichomonas vaginalis AGC family protein kinase 0.0242 0.0296 0.0842
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Leishmania major hypothetical protein, conserved 0.0381 0.0642 0.0615
Leishmania major acetoin dehydrogenase e3 component-like protein 0.1435 0.3265 0.3246
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0206 0.0207 0.0199
Schistosoma mansoni protein kinase 0.0896 0.1922 0.1915
Loa Loa (eye worm) hypothetical protein 0.0208 0.0211 0.0203
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0323 0.0498 0.0393
Loa Loa (eye worm) hypothetical protein 0.0135 0.0029 0.0021
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0231 0.0268 0.024
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0374 0.0625 0.0625
Entamoeba histolytica protein kinase, putative 0.021 0.0218 0.1211
Loa Loa (eye worm) LAD-2 short isoform 0.0225 0.0254 0.0246
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0381 0.0642 0.0615
Trichomonas vaginalis AGC family protein kinase 0.0281 0.0392 0.1138
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0381 0.0642 0.0634
Trypanosoma cruzi Protein kinase B 0.0339 0.0536 0.0509
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0303 0.0863
Echinococcus granulosus neuroglian 0.0922 0.1988 0.1988
Echinococcus granulosus tyrosine protein kinase Src64B 0.0315 0.0476 0.0476
Giardia lamblia Aurora kinase 0.0242 0.0296 0.0575
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1672 0.3854 0.3849
Echinococcus multilocularis expressed conserved protein 0.0173 0.0124 0.0124
Echinococcus multilocularis 0.0316 0.048 0.048
Entamoeba histolytica protein kinase domain containing protein 0.0287 0.0407 0.2392
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1435 0.3265 0.3246
Trichomonas vaginalis AGC family protein kinase 0.0603 0.1194 0.3611
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0233 0.0274 0.0274
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0123 0.0308
Schistosoma mansoni sulfide quinone reductase 0.0381 0.0642 0.0634
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1435 0.3265 0.3246
Echinococcus multilocularis protein kinase shaggy 0.0265 0.0354 0.0354
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0655 0.1323 0.1316
Leishmania major casein kinase, putative 0.0224 0.0251 0.0223
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0208 0.0211 0.0211
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0287 0.0407 0.0379
Onchocerca volvulus 0.0187 0.0158 0.0731
Echinococcus multilocularis epidermal growth factor receptor 0.0497 0.093 0.093
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1435 0.3265 1
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0418 0.0734 0.0726
Trichomonas vaginalis CAMK family protein kinase 0.0161 0.0094 0.0219
Loa Loa (eye worm) hypothetical protein 0.0287 0.0407 0.0399
Loa Loa (eye worm) notch protein 0.0419 0.0735 0.0728
Echinococcus granulosus protein jagged 2 0.0419 0.0735 0.0735
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.102 0.2233 0.2233
Echinococcus multilocularis dual specificity 0.0252 0.0321 0.0321
Schistosoma mansoni cell adhesion molecule 0.0225 0.0254 0.0246
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0245 0.0303 0.0275
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0154 0.0077 0.0077
Schistosoma mansoni tyrosine kinase 0.043 0.0764 0.0756
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0419 0.0735 0.0728
Brugia malayi EGF-like domain containing protein 0.0419 0.0735 0.0728
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0728 0.1504 0.7778
Loa Loa (eye worm) cyclin C 0.1536 0.3515 0.3509
Schistosoma mansoni titin 0.0187 0.0158 0.015
Leishmania major protein kinase, putative 0.0174 0.0128 0.0099
Echinococcus granulosus rho-associated protein kinase 1 0.0671 0.1363 0.1363
Brugia malayi protein unc-22 0.0273 0.0373 0.0365
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0187 0.0158 0.015
Schistosoma mansoni tyrosine kinase 0.0315 0.0476 0.0469
Echinococcus multilocularis aurora kinase A 0.0242 0.0296 0.0296
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0757 0.1577 0.1577
Onchocerca volvulus 0.0132 0.0023 0.0023
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.1054 0.2317 0.2311
Echinococcus granulosus calcium dependent protein kinase 0.014 0.0042 0.0042
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0161 0.0094 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.0205 0.0204 0.0197
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0173 0.0124 0.0096
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0412 0.0718 0.0718
Brugia malayi Immunoglobulin I-set domain containing protein 0.0225 0.0254 0.0246
Brugia malayi EGF-like domain containing protein 0.0464 0.0849 0.0842
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0173 0.0123 0.0095
Toxoplasma gondii CMGC kinase, CK2 family 0.0206 0.0207 0.0179
Brugia malayi Casein kinase II, alpha chain 0.0206 0.0207 0.0199
Echinococcus multilocularis titin 0.0273 0.0373 0.0373
Echinococcus granulosus protein kinase c epsilon type 0.0421 0.0741 0.0741
Loa Loa (eye worm) TK/FER protein kinase 0.0449 0.0811 0.0803
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0299 0.0437 0.0437
Echinococcus granulosus STE20 serine:threonine protein kinase 0.102 0.2233 0.2233
Schistosoma mansoni protein kinase C mu 0.0449 0.0811 0.0803
Schistosoma mansoni protein kinase 0.0456 0.0828 0.082
Loa Loa (eye worm) hypothetical protein 0.0187 0.0158 0.015
Echinococcus granulosus low density lipoprotein receptor ldl 0.0225 0.0254 0.0254
Echinococcus granulosus cyclin dependent kinase 1 0.0245 0.0303 0.0303
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0323 0.0498 0.047
Leishmania major NADH dehydrogenase, putative 0.0381 0.0642 0.0615
Echinococcus multilocularis 0.0197 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0381 0.0642 0.0634
Onchocerca volvulus 0.0135 0.0029 0.0057
Plasmodium falciparum serine/threonine protein kinase KIN 0.0161 0.0094 0.0066
Loa Loa (eye worm) hypothetical protein 0.0773 0.1617 0.161
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0225 0.0254 0.0254

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) = 3.7 uM Cytostatic concentration of the compound required to inhibit MT-4 cell proliferation ChEMBL. 15715482
CC50 (functional) = 4.36 uM Cytostatic concentration of the compound required to inhibit CEM cell proliferation ChEMBL. 15715482
CC50 (functional) = 11 uM Cytostatic concentration required to inhibit HEL cell proliferation ChEMBL. 15715482
EC50 (functional) > 2 uM Effective concentration of the compound required to inhibit HIV-1 IIIB in MT-4 cell culture ChEMBL. 15715482
EC50 (functional) > 2 uM Effective concentration of the compound required to inhibit HIV-2 ROD in MT-4 cell culture ChEMBL. 15715482
EC50 (functional) > 2 uM Effective concentration of the compound required to inhibit HIV-1 IIIB in CEM cell culture ChEMBL. 15715482
EC50 (functional) > 2 uM Effective concentration of the compound required to inhibit HIV-2 ROD in CEM cell culture ChEMBL. 15715482
EC50 (functional) = 2 uM Effective concentration of the compound required to inhibit HCMV Davis in HEL Cells ChEMBL. 15715482
EC50 (functional) > 3.2 uM Effective concentration of the compound required to inhibit HCMV AD-169 in HEL Cells ChEMBL. 15715482
MCC (functional) = 16 uM Minimal cytotoxic concentration required to cause microscopically visible alteration of cell morphology in HEL Cells ChEMBL. 15715482

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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