Detailed information for compound 314478

Basic information

Technical information
  • TDR Targets ID: 314478
  • Name: methyl 4-(3-hydroxy-4-methylanilino)-5-methyl pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
  • MW: 312.323 | Formula: C16H16N4O3
  • H donors: 2 H acceptors: 4 LogP: 2.51 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1cn2c(c1C)c(ncn2)Nc1ccc(c(c1)O)C
  • InChi: 1S/C16H16N4O3/c1-9-4-5-11(6-13(9)21)19-15-14-10(2)12(16(22)23-3)7-20(14)18-8-17-15/h4-8,21H,1-3H3,(H,17,18,19)
  • InChiKey: DWVFNSMCXULVNR-UHFFFAOYSA-N  

Network

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Synonyms

  • methyl 4-(3-hydroxy-4-methyl-anilino)-5-methyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
  • 4-(3-hydroxy-4-methylanilino)-5-methyl-6-pyrrolo[2,1-f][1,2,4]triazinecarboxylic acid methyl ester
  • methyl 4-[(3-hydroxy-4-methyl-phenyl)amino]-5-methyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
  • 4-(3-hydroxy-4-methyl-anilino)-5-methyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid methyl ester
  • methyl 4-[(3-hydroxy-4-methylphenyl)amino]-5-methylpyrrolo[5,1-f][1,2,4]triazine-6-carboxylate
  • methyl 4-[(3-hydroxy-4-methyl-phenyl)amino]-5-methyl-pyrrolo[5,1-f][1,2,4]triazine-6-carboxylate
  • 4-[(3-hydroxy-4-methylphenyl)amino]-5-methyl-6-pyrrolo[5,1-f][1,2,4]triazinecarboxylic acid methyl ester
  • 4-[(3-hydroxy-4-methyl-phenyl)amino]-5-methyl-pyrrolo[5,1-f][1,2,4]triazine-6-carboxylic acid methyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Onchocerca volvulus 0.0193 0.0351 0.0967
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0271 0.0715 0.0671
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Schistosoma mansoni basigin related 0.0136 0.0086 0.0086
Entamoeba histolytica protein kinase, putative 0.0298 0.0844 0.2203
Entamoeba histolytica protein kinase, putative 0.0139 0.0099 0.0041
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Echinococcus granulosus neurogenic locus notch protein 4 0.0229 0.0519 0.0474
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.033 0.0991 0.0901
Loa Loa (eye worm) cyclin C 0.1724 0.7486 0.7486
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0136 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Blk 0.0258 0.0656 0.0611
Echinococcus multilocularis neuroglian 0.0271 0.0715 0.0671
Onchocerca volvulus 0.0136 0.0085 0.0187
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0292 0.0816 0.0567
Loa Loa (eye worm) hypothetical protein 0.048 0.1691 0.1691
Echinococcus granulosus epidermal growth factor receptor 0.0496 0.1767 0.1727
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.018 0.0291 0.0195
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0784 0.3108 0.304
Leishmania major NADH dehydrogenase, putative 0.0208 0.0423 0.0328
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0715 0.2787 0.2787
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Brugia malayi Variant SH3 domain containing protein 0.0158 0.0188 0.0188
Toxoplasma gondii rhoptry neck protein RON1 0.0422 0.1421 0.1336
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0803 0.0803
Brugia malayi Cyclin, N-terminal domain containing protein 0.0862 0.3473 0.3473
Schistosoma mansoni titin 0.0252 0.0628 0.0628
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0844 0.2716
Loa Loa (eye worm) hypothetical protein 0.0227 0.0511 0.0511
Plasmodium vivax protein kinase Crk2 0.0255 0.0642 0.0389
Echinococcus multilocularis epidermal growth factor receptor 0.0496 0.1767 0.1727
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0318 0.0934 0.089
Echinococcus granulosus c-Jun N-terminal kinases 0.0567 0.2098 0.206
Schistosoma mansoni hypothetical protein 0.0219 0.0473 0.0473
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0784 0.3108 1
Brugia malayi Peroxidasin 0.0253 0.0631 0.0631
Brugia malayi Protein kinase domain 0.0185 0.0314 0.0314
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0182 0.03 0.03
Loa Loa (eye worm) hypothetical protein 0.0991 0.4072 0.4072
Brugia malayi intracellular kinase 0.0276 0.0741 0.0741
Loa Loa (eye worm) AGC/PKA protein kinase 0.0243 0.0584 0.0584
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0208 0.0423 0.0982
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0262 0.0677 0.0677
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0295 0.0827 0.2661
Echinococcus multilocularis c src tyrosine kinase 0.0195 0.0363 0.0317
Loa Loa (eye worm) hypothetical protein 0.0211 0.0437 0.0437
Onchocerca volvulus 0.0422 0.1421 0.4098
Echinococcus granulosus dual specificity 0.0298 0.0844 0.08
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0136 0.0088 0.0088
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0642 0.2066
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2023 0.8881 0.8881
Schistosoma mansoni hemicentin 0.0135 0.0083 0.0083
Echinococcus granulosus cyclin dependent kinase 9 0.0183 0.0305 0.0259
Onchocerca volvulus 0.0422 0.1421 0.4098
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0136 0.0086 0.0038
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0208 0.0423 0.0328
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0174 0.0263 0.0167
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0342 0.1046 0.1046
Loa Loa (eye worm) AGC/PKG protein kinase 0.0174 0.0263 0.0263
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.024 0.0572 0.0572
Echinococcus multilocularis fibropellin Ia 0.0229 0.0519 0.0474
Loa Loa (eye worm) hypothetical protein 0.0252 0.0628 0.0628
Onchocerca volvulus 0.0136 0.0085 0.0187
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0208 0.0423 0.0423
Onchocerca volvulus 0.0193 0.0351 0.0967
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0311 0.0901 0.0858
Toxoplasma gondii AGC kinase 0.0243 0.0584 0.0491
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0178 0.0285 0.0285
Onchocerca volvulus 0.0208 0.0423 0.1177
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0154 0.0172 0.0125
Brugia malayi MAP kinase sur-1 0.018 0.0291 0.0291
Brugia malayi Calcium binding EGF domain containing protein 0.0229 0.0519 0.0519
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0784 0.3108 0.304
Loa Loa (eye worm) hypothetical protein 0.0376 0.1204 0.1204
Trichomonas vaginalis CAMK family protein kinase 0.0271 0.0718 0.231
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0252 0.0628 0.0628
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.033 0.0991 0.0901
Onchocerca volvulus Tyrosine kinase homolog 0.0855 0.3437 1
Loa Loa (eye worm) Notch2 0.0229 0.0519 0.0519
Brugia malayi Protein kinase domain containing protein 0.0345 0.106 0.106
Schistosoma mansoni slit 0.0229 0.0521 0.0521
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0431 0.1462 0.1421
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0208 0.0423 0.1362
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0185 0.0314 0.0268
Loa Loa (eye worm) AUR protein kinase 0.0249 0.0612 0.0612
Schistosoma mansoni hypothetical protein 0.0136 0.0086 0.0086
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0208 0.0423 0.0164
Loa Loa (eye worm) hypothetical protein 0.0376 0.1204 0.1204
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0642 0.0642
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.304
Onchocerca volvulus 0.0422 0.1421 0.4098
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.3108
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0127 0.0048 0.0048
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0182 0.03 0.0625
Loa Loa (eye worm) AGC/AKT protein kinase 0.0626 0.2373 0.2373
Echinococcus multilocularis hemicentin 1 0.0252 0.0628 0.0584
Brugia malayi Fes/CIP4 homology domain containing protein 0.0218 0.0469 0.0469
Schistosoma mansoni basigin related 0.0136 0.0086 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0844 0.0844
Trypanosoma cruzi NADH dehydrogenase, putative 0.0208 0.0423 0.0423
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0437 0.1491 0.1491
Schistosoma mansoni hypothetical protein 0.0136 0.0086 0.0086
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Entamoeba histolytica hypothetical protein 0.0385 0.125 0.3381
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.024 0.0572 0.0572
Trichomonas vaginalis STE family protein kinase 0.0185 0.0314 0.101
Trichomonas vaginalis STE family protein kinase 0.0185 0.0314 0.101
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0166 0.0229 0.0229
Trichomonas vaginalis AGC family protein kinase 0.0249 0.0612 0.1969
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0784 0.3108 1
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0431 0.1462 0.1421
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Echinococcus granulosus Glutaredoxin protein 5 0.0266 0.0691 0.0647
Giardia lamblia Kinase, NEK 0.0292 0.0816 0.188
Plasmodium falciparum serine/threonine protein kinase 0.0178 0.0285 0.0188
Echinococcus multilocularis cyclin dependent kinase 1 0.0255 0.0642 0.0597
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0208 0.0423 0.0982
Giardia lamblia High cysteine protein 0.0229 0.0519 0.0829
Onchocerca volvulus 0.0698 0.2707 0.7864
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0208 0.0423 0.0378
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0083 0.0083
Plasmodium falciparum thioredoxin reductase 0.0784 0.3108 0.304
Trypanosoma brucei aurora B kinase 0.0249 0.0612 0.0519
Loa Loa (eye worm) hypothetical protein 0.0259 0.0661 0.0661
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Echinococcus granulosus serine:threonine protein kinase 3 0.0552 0.2024 0.1986
Loa Loa (eye worm) hypothetical protein 0.0245 0.0595 0.0595
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0252 0.0628 0.0584
Schistosoma mansoni nck2/grb4 0.0127 0.0048 0.0048
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0963 0.3943 0.3943
Schistosoma mansoni g1/s-specific cyclin C 0.1724 0.7486 0.7486
Loa Loa (eye worm) hypothetical protein 0.0136 0.0086 0.0086
Onchocerca volvulus 0.0229 0.0519 0.1457
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.058 0.2158 0.2158
Loa Loa (eye worm) gastrulation defective protein 1 0.1091 0.4537 0.4537
Plasmodium falciparum casein kinase 1 0.0233 0.0541 0.0447
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0276 0.0741 0.0741
Echinococcus granulosus tyrosine kinase 0.0136 0.0085 0.0038
Schistosoma mansoni adapter molecule crk 0.0127 0.0048 0.0048
Brugia malayi Doublecortin family protein 0.0324 0.0963 0.0963
Schistosoma mansoni serine/threonine protein kinase 0.0458 0.1587 0.1587
Echinococcus granulosus raf serine:threonine protein kinase 0.0158 0.0187 0.0141
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0247 0.0605 0.056
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0862 0.3473 0.3442
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0185 0.0314 0.0268
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0208 0.0423 0.1362
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0336 0.1021 0.0931
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0243 0.0584 0.0584
Echinococcus granulosus protein jagged 2 0.0229 0.0519 0.0474
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0365 0.1157 0.1157
Schistosoma mansoni tyrosine kinase 0.0408 0.1356 0.1356
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0352 0.1096 0.1096
Schistosoma mansoni notch 0.0229 0.0519 0.0519
Schistosoma mansoni glutamate synthase 0.0208 0.0423 0.0423
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0784 0.3108 1
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.106 0.106
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Giardia lamblia Kinase, PLK 0.058 0.2158 0.6636
Echinococcus granulosus protein tyrosine kinase 0.0581 0.2161 0.2124
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0166 0.0229 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.1335 0.5677 0.5677
Brugia malayi Protein kinase domain containing protein 0.0136 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0208 0.0423 0.0423
Echinococcus multilocularis Immunoglobulin 0.0136 0.0086 0.0038
Echinococcus multilocularis N chimaerin 0.0158 0.0188 0.0142
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0847 0.3399 0.3367
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0291 0.0937
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Giardia lamblia Kinase, CMGC GSK 0.0276 0.0741 0.1616
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0584 0.0584
Brugia malayi notch-like transmembrane receptor 0.0229 0.0519 0.0519
Trypanosoma cruzi aurora B kinase, putative 0.0249 0.0612 0.0612
Schistosoma mansoni protein kinase 0.0233 0.0541 0.0541
Trypanosoma brucei NADH dehydrogenase 0.0208 0.0423 0.0328
Trichomonas vaginalis mercuric reductase, putative 0.0784 0.3108 1
Trichomonas vaginalis AGC family protein kinase 0.0249 0.0612 0.1969
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0276 0.0741 0.0649
Brugia malayi Protein kinase domain containing protein 0.0646 0.2463 0.2463
Schistosoma mansoni serine/threonine protein kinase 0.0847 0.3399 0.3399
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0229 0.0229
Brugia malayi Protein kinase domain containing protein 0.0255 0.0642 0.0642
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0247 0.0605 0.056
Brugia malayi hypothetical protein 0.0136 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0542 0.198 0.198
Trypanosoma cruzi cdc2-related kinase 3 0.0255 0.0642 0.0642
Leishmania major protein kinase A catalytic subunit isoform 2 0.0243 0.0584 0.0491
Giardia lamblia Thioredoxin reductase 0.0208 0.0423 0.0491
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.033 0.0991 0.0991
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.0326 0.0326
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0255 0.0642 0.0549
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0252 0.0628 0.0628
Echinococcus multilocularis transfer RNA-Phe 0.0135 0.0083 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0715 0.0715
Trypanosoma cruzi cdc2-related kinase 1 0.0255 0.0642 0.0642
Toxoplasma gondii histone kinase SNF1, putative 0.0166 0.0229 0.0131
Schistosoma mansoni protein kinase 0.0472 0.1655 0.1655
Echinococcus multilocularis dual specificity protein kinase clk2 0.033 0.0991 0.0948
Trichomonas vaginalis AGC family protein kinase 0.0249 0.0612 0.1969
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0264 0.0684 0.0684
Brugia malayi Immunoglobulin I-set domain containing protein 0.0252 0.0628 0.0628
Schistosoma mansoni titin 0.0206 0.0412 0.0412
Brugia malayi Immunoglobulin I-set domain containing protein 0.0198 0.0375 0.0375
Echinococcus granulosus fibropellin Ia 0.0229 0.0519 0.0474
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0083 0.0083
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.018 0.0291 0.0291
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0298 0.0844 0.0844
Echinococcus granulosus N chimaerin 0.0158 0.0188 0.0142
Echinococcus granulosus protein kinase C gamma type 0.0433 0.1469 0.1429
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0217 0.0462 0.0368
Loa Loa (eye worm) TK/ROR protein kinase 0.0184 0.0312 0.0312
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0757 0.2982 0.2982
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0245 0.0595 0.0595
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Schistosoma mansoni kinase 0.0166 0.0227 0.0227
Plasmodium falciparum ferrodoxin reductase-like protein 0.0208 0.0423 0.0328
Loa Loa (eye worm) hypothetical protein 0.0646 0.2463 0.2463
Onchocerca volvulus 0.0136 0.0085 0.0187
Echinococcus granulosus mitogen activated protein kinase 3 0.018 0.0291 0.0245
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0263 0.0263
Echinococcus granulosus protein jagged 2 0.0229 0.0519 0.0474
Onchocerca volvulus 0.0135 0.0083 0.018
Schistosoma mansoni protein kinase 0.0138 0.0097 0.0097
Echinococcus granulosus cyclin dependent kinase 1 0.0255 0.0642 0.0597
Echinococcus granulosus protein jagged 1 0.0229 0.0519 0.0474
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0464 0.1615 0.1575
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0217 0.0462 0.0204
Brugia malayi Protein kinase domain containing protein 0.0626 0.2373 0.2373
Echinococcus granulosus casein kinase I alpha 0.0233 0.0541 0.0495
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0844 0.2716
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0255 0.0642 0.0549
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0252 0.0628 0.0628
Echinococcus granulosus tyrosine protein kinase Src64B 0.0318 0.0934 0.089
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0862 0.3473 0.3442
Brugia malayi Protein kinase domain containing protein 0.0757 0.2982 0.2982
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0336 0.1021 0.0978
Trypanosoma brucei protein kinase, putative 0.0276 0.0741 0.0649
Brugia malayi Protein kinase domain containing protein 0.0466 0.1625 0.1625
Schistosoma mansoni growth factor receptor-bound protein 0.013 0.0057 0.0057
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.018 0.0291 0.0291
Plasmodium vivax ferrodoxin reductase, putative 0.0208 0.0423 0.0164
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Trypanosoma brucei SNF1-related protein kinases, putative 0.0166 0.0229 0.0131
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0271 0.0715 0.0671
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.024 0.0572 0.0478
Echinococcus multilocularis mitogen activated protein kinase 11 0.0342 0.1046 0.1003
Giardia lamblia Kinase, AGC PKA 0.0336 0.1021 0.2607
Echinococcus multilocularis neurogenic locus notch protein 0.0229 0.0519 0.0474
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0784 0.3108 0.304
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0217 0.0462 0.0417
Echinococcus multilocularis tyrosine protein kinase shark 0.0352 0.1095 0.1052
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0336 0.1021 0.0978
Brugia malayi phosphoinositide-dependent protein kinase I 0.0175 0.0269 0.0269
Schistosoma mansoni septate junction protein 0.0229 0.0519 0.0519
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0217 0.0462 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.106 0.106
Schistosoma mansoni notch 0.0229 0.0519 0.0519
Brugia malayi cyclin-dependent kinase 9 0.0166 0.0227 0.0227
Echinococcus granulosus titin 0.0206 0.0412 0.0367
Schistosoma mansoni vam6/vps39 related 0.024 0.0572 0.0572
Echinococcus granulosus expressed protein 0.0178 0.0285 0.0238
Echinococcus multilocularis cyclin dependent kinase 0.0255 0.0642 0.0597
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0206 0.0412 0.0412
Entamoeba histolytica cyclin C, putative 0.0875 0.353 1
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Brugia malayi Immunoglobulin domain containing protein 0.0136 0.0086 0.0086
Onchocerca volvulus 0.0276 0.0741 0.2107
Entamoeba histolytica protein kinase, putative 0.0626 0.2373 0.664
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0208 0.0423 0.0423
Schistosoma mansoni serine/threonine protein kinase 0.0435 0.1481 0.1481
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0195 0.0363 0.0363
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0136 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0135 0.0083 0.0083
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0466 0.1624 0.1584
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0208 0.0423 0.0491
Echinococcus granulosus neurogenic locus protein delta 0.0229 0.0519 0.0474
Loa Loa (eye worm) casein kinase 0.0387 0.1258 0.1258
Brugia malayi Prion-like- 0.0252 0.0628 0.0628
Loa Loa (eye worm) hypothetical protein 0.0413 0.1376 0.1376
Echinococcus granulosus roundabout 2 0.0732 0.2866 0.2832
Plasmodium vivax glycogen synthase kinase 3, putative 0.0276 0.0741 0.049
Plasmodium vivax casein kinase 1, putative 0.0233 0.0541 0.0284
Echinococcus granulosus cyclin 0.0862 0.3473 0.3442
Brugia malayi Protein kinase domain containing protein 0.0136 0.0085 0.0085
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0276 0.0741 0.0741
Entamoeba histolytica casein kinase 1, putative 0.0233 0.0541 0.1322
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0271 0.0715 0.0715
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.3108
Trichomonas vaginalis glutamate synthase, putative 0.0208 0.0423 0.1362
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Schistosoma mansoni notch 0.0229 0.0519 0.0519
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0136 0.0086 0.0038
Entamoeba histolytica PH domain containing protein kinase, putative 0.0352 0.1096 0.2933
Echinococcus granulosus tyrosine protein kinase Srms 0.0549 0.2013 0.1974
Entamoeba histolytica protein kinase, putative 0.0626 0.2373 0.664
Trichomonas vaginalis CAMK family protein kinase 0.058 0.2158 0.6944
Schistosoma mansoni serine/threonine protein kinase 0.0464 0.1615 0.1615
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0932 0.3796 0.3767
Entamoeba histolytica protein kinase domain containing protein 0.0249 0.0612 0.1529
Echinococcus multilocularis death associated protein kinase 1 0.0898 0.3638 0.3607
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Trichomonas vaginalis CAMK family protein kinase 0.0217 0.0462 0.1488
Echinococcus multilocularis 0.0196 0.0365 0.0319
Onchocerca volvulus 0.0136 0.0085 0.0187
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0266 0.0691 0.0647
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0311 0.0901 0.0858
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0584 0.0584
Echinococcus multilocularis protein jagged 1 0.0229 0.0519 0.0474
Loa Loa (eye worm) hypothetical protein 0.0127 0.0048 0.0048
Plasmodium vivax unspecified product 0.0215 0.0455 0.0196
Brugia malayi EGF-like domain containing protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1162 0.4867 0.4867
Echinococcus granulosus growth factor receptor bound protein 2 0.013 0.0057 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0726 0.2836 0.2836
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0788 0.3124 0.3091
Echinococcus granulosus protein kinase c epsilon type 0.0437 0.1491 0.1451
Schistosoma mansoni protein kinase 0.0932 0.3796 0.3796
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0208 0.0423 0.0328
Brugia malayi Immunoglobulin I-set domain containing protein 0.0252 0.0628 0.0628
Plasmodium falciparum glutathione reductase 0.0784 0.3108 0.304
Echinococcus granulosus mitogen activated protein kinase 14 0.0342 0.1046 0.1003
Brugia malayi map kinase activated protein kinase protein 2 0.0847 0.3399 0.3399
Loa Loa (eye worm) TK/ABL protein kinase 0.0136 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0252 0.0628 0.0628
Echinococcus granulosus C type lectin domian containing protein 0.0422 0.1421 0.138
Echinococcus multilocularis activin receptor type 0.0138 0.0098 0.0051
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0136 0.0086 0.0038
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0784 0.3108 0.2803
Echinococcus multilocularis serine:threonine protein kinase N2 0.0278 0.0751 0.0707
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0243 0.0584 0.0329
Brugia malayi Protein kinase domain containing protein 0.0414 0.1383 0.1383
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0318 0.0934 0.089
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Plasmodium vivax glutathione reductase, putative 0.2263 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.048 0.1691 0.1691
Echinococcus multilocularis hemicentin 1 0.0252 0.0628 0.0584
Entamoeba histolytica protein kinase, putative 0.0276 0.0741 0.1903
Schistosoma mansoni tyrosine kinase 0.0624 0.2361 0.2361
Loa Loa (eye worm) TK/EPH protein kinase 0.0243 0.0585 0.0585
Schistosoma mansoni septate junction protein 0.0136 0.0086 0.0086
Schistosoma mansoni atypical protein kinase C 0.0626 0.2369 0.2369
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0182 0.03 0.0625
Giardia lamblia Glutamate synthase 0.0208 0.0423 0.0491
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0345 0.106 0.1017
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0185 0.0314 0.0268
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0135 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0136 0.0086 0.0086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0252 0.0628 0.0628
Schistosoma mansoni hypothetical protein 0.0219 0.0473 0.0473
Loa Loa (eye worm) AGC/PKA protein kinase 0.0243 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.024 0.0572 0.0572
Toxoplasma gondii aurora kinase 0.0249 0.0612 0.0519
Trichomonas vaginalis STE family protein kinase 0.0185 0.0314 0.101
Echinococcus granulosus casein kinase I gamma 0.0458 0.1587 0.1547
Entamoeba histolytica protein kinase, putative 0.061 0.2298 0.6422
Schistosoma mansoni basigin related 0.0136 0.0086 0.0086
Brugia malayi EGF-like domain containing protein 0.0229 0.0519 0.0519
Trypanosoma cruzi trypanothione reductase, putative 0.2263 1 1
Brugia malayi Sex muscle abnormal protein 5 0.0127 0.0048 0.0048
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0505 0.1805 0.1766
Echinococcus multilocularis tyrosine protein kinase 0.0311 0.0902 0.0859
Schistosoma mansoni serine/threonine protein kinase 0.033 0.0991 0.0991
Trypanosoma brucei protein kinase, putative 0.0196 0.0369 0.0273
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0127 0.0048 0.0048
Echinococcus granulosus dual specificity 0.0298 0.0844 0.08
Entamoeba histolytica protein kinase domain containing protein 0.0262 0.0677 0.1716
Brugia malayi Protein kinase domain containing protein 0.0308 0.0887 0.0887
Entamoeba histolytica PH domain containing protein kinase, putative 0.0352 0.1096 0.2933
Entamoeba histolytica protein kinase domain containing protein 0.0215 0.0455 0.1074
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0172 0.0255 0.0208
Onchocerca volvulus 0.0422 0.1421 0.4098
Echinococcus granulosus neuroglian 0.0271 0.0715 0.0671
Loa Loa (eye worm) hypothetical protein 0.0192 0.0347 0.0347
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0844 0.2716
Trypanosoma cruzi Protein kinase B 0.0352 0.1096 0.1096
Loa Loa (eye worm) thyroid receptor interactor 0.0218 0.0469 0.0469
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0262 0.0677 0.0677
Brugia malayi Protein kinase domain containing protein 0.033 0.0991 0.0991
Onchocerca volvulus 0.0627 0.2378 0.6899
Echinococcus granulosus casein kinase i 0.0233 0.0541 0.0495
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0464 0.1615 0.1575
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0443 0.1519 0.1479
Echinococcus multilocularis casein kinase I alpha 0.0233 0.0541 0.0495
Echinococcus granulosus cGMP dependent protein kinase 0.0174 0.0263 0.0217
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Trichomonas vaginalis AGC family protein kinase 0.0175 0.0269 0.0864
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0163 0.0211 0.0211
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0154 0.0172 0.0125
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0208 0.0423 0.0423
Brugia malayi Immunoglobulin domain containing protein 0.0136 0.0086 0.0086
Brugia malayi EGF-like domain containing protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) CAMK protein kinase 0.0206 0.0412 0.0412
Toxoplasma gondii thioredoxin reductase 0.2263 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0567 0.2098 0.2098
Echinococcus multilocularis thioredoxin glutathione reductase 0.2263 1 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0307 0.0883 0.0883
Schistosoma mansoni tyrosine kinase 0.0624 0.2361 0.2361
Echinococcus multilocularis neurogenic locus notch protein 0.0229 0.0519 0.0474
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0264 0.0684 0.064
Brugia malayi Protein kinase domain containing protein 0.0963 0.3943 0.3943
Echinococcus multilocularis serine threonine protein kinase 0.0433 0.1469 0.1429
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0208 0.0423 0.1362
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0336 0.1021 0.1021
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.018 0.0291 0.0291
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0435 0.1481 0.144
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0311 0.0903 0.0859
Echinococcus multilocularis cyclin dependent kinase 9 0.0166 0.0227 0.0181
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0784 0.3108 1
Giardia lamblia Kinase, STE STE20 0.0182 0.03 0.0055
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0464 0.1615 0.1575
Loa Loa (eye worm) glutathione reductase 0.2263 1 1
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0208 0.0423 0.0328
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0351 0.1131
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.018 0.0291 0.0291
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0784 0.3108 0.2803
Giardia lamblia Kinase, AGC AKT 0.0251 0.0625 0.1204
Schistosoma mansoni vav2 0.0174 0.0263 0.0263
Echinococcus multilocularis dual specificity 0.0298 0.0844 0.08
Onchocerca volvulus 0.024 0.0572 0.1612
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0175 0.0269 0.0222
Echinococcus multilocularis PAK box P21 Rho binding 0.0138 0.0097 0.005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0217 0.0462 0.0462
Echinococcus multilocularis netrin receptor unc 5 0.0198 0.0375 0.0329
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0262 0.0677 0.0584
Loa Loa (eye worm) hypothetical protein 0.0298 0.0842 0.0842
Schistosoma mansoni notch 0.0229 0.0519 0.0519
Entamoeba histolytica thioredoxin reductase, putative 0.0208 0.0423 0.0982
Echinococcus multilocularis 0.0329 0.0986 0.0943
Echinococcus multilocularis rac serine:threonine kinase 0.0352 0.1096 0.1053
Schistosoma mansoni tyrosine kinase 0.0381 0.123 0.123
Loa Loa (eye worm) hypothetical protein 0.0388 0.1261 0.1261
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Trypanosoma brucei cdc2-related kinase 3 0.0255 0.0642 0.0549
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0208 0.0423 0.0982
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0466 0.1625 0.1625
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0276 0.0741 0.0697
Schistosoma mansoni protein kinase C mu 0.0467 0.1631 0.1631
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Giardia lamblia Aurora kinase 0.0249 0.0612 0.1159
Echinococcus granulosus tyrosine protein kinase otk 0.0252 0.0628 0.0584
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0612 0.0612
Echinococcus multilocularis neural cadherin 0.0229 0.0519 0.0474
Loa Loa (eye worm) TK/FAK protein kinase 0.0587 0.219 0.219
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0208 0.0423 0.0328
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0298 0.0844 0.0844
Leishmania major trypanothione reductase 0.2263 1 1
Echinococcus multilocularis roundabout 2 0.0271 0.0715 0.0671
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0184 0.0312 0.0265
Trypanosoma cruzi trypanothione reductase, putative 0.0784 0.3108 0.3108
Echinococcus multilocularis serine:threonine protein kinase 3 0.0552 0.2024 0.1986
Trichomonas vaginalis AGC family protein kinase 0.0365 0.1157 0.3721
Schistosoma mansoni serine/threonine protein kinase 0.058 0.2158 0.2158
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0522 0.1888 0.1849
Entamoeba histolytica casein kinase, putative 0.0215 0.0455 0.1074
Brugia malayi protein unc-22 0.0206 0.0412 0.0412
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0318 0.0934 0.089
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.058 0.2158 0.208
Entamoeba histolytica protein kinase, putative 0.019 0.0339 0.0738
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Echinococcus multilocularis serine:threonine protein kinase N2 0.0345 0.106 0.1017
Trichomonas vaginalis AGC family protein kinase 0.0192 0.0346 0.1115
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0466 0.1624 0.1584
Echinococcus granulosus neurogenic locus notch protein 0.0229 0.0519 0.0474
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.018 0.0291 0.0291
Loa Loa (eye worm) TK/ALK protein kinase 0.0308 0.0887 0.0887
Echinococcus multilocularis nervana 2 0.0266 0.0691 0.0647
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0217 0.0462 0.0204
Giardia lamblia Kinase, STE STE20 0.0185 0.0314 0.0103
Schistosoma mansoni notch 0.0229 0.0519 0.0519
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0178 0.0285 0.0188
Leishmania major hypothetical protein, conserved 0.0208 0.0423 0.0328
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.061 0.2298 0.2298
Schistosoma mansoni serine/threonine protein kinase 0.0431 0.1462 0.1462
Schistosoma mansoni septate junction protein 0.0252 0.0628 0.0628
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0255 0.0642 0.0642
Brugia malayi SH2 domain containing protein 0.0443 0.1519 0.1519
Loa Loa (eye worm) hypothetical protein 0.0137 0.0094 0.0094
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0276 0.0741 0.0741
Echinococcus granulosus tyrosine protein kinase shark 0.0352 0.1095 0.1052
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0208 0.0423 0.1362
Brugia malayi Calcium binding EGF domain containing protein 0.0229 0.0519 0.0519
Leishmania major protein kinase, putative 0.033 0.0991 0.0901
Plasmodium falciparum cGMP-dependent protein kinase 0.0174 0.0263 0.0167
Schistosoma mansoni cell adhesion molecule 0.0136 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0318 0.0934 0.0934
Trichomonas vaginalis AGC family protein kinase 0.0292 0.0816 0.2625
Echinococcus granulosus insulin receptor 0.0624 0.2361 0.2325
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0677 0.0677
Loa Loa (eye worm) hypothetical protein 0.0461 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0219 0.0473 0.0473
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0262 0.0677 0.0677
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0158 0.0188 0.0188
Schistosoma mansoni protein kinase 0.0249 0.0612 0.0612
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0784 0.3108 0.3108
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0122 0.0021 0.0021
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.024 0.0572 0.0572
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0784 0.3108 0.304
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0467 0.1631 0.1631
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Schistosoma mansoni protein kinase 0.0138 0.0098 0.0098
Brugia malayi hypothetical protein 0.0136 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0136 0.0086 0.0086
Schistosoma mansoni neuroglian 0.0271 0.0715 0.0715
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0249 0.0612 0.0567
Onchocerca volvulus Netrin receptor homolog 0.0179 0.0285 0.0774
Schistosoma mansoni tyrosine kinase 0.0581 0.2161 0.2161
Brugia malayi Cyclin C 0.1724 0.7486 0.7486
Schistosoma mansoni protein kinase 0.0788 0.3124 0.3124
Trypanosoma brucei cdc2-related kinase 1 0.0255 0.0642 0.0549
Loa Loa (eye worm) cyclin domain-containing protein 0.0862 0.3473 0.3473
Onchocerca volvulus 0.0298 0.0842 0.2404
Schistosoma mansoni tyrosine kinase 0.0496 0.1767 0.1767
Brugia malayi Protein kinase domain containing protein 0.0311 0.0902 0.0902
Loa Loa (eye worm) hypothetical protein 0.0136 0.0086 0.0086
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0243 0.0584 0.0491
Echinococcus granulosus tyrosine protein kinase Fyn 0.0318 0.0934 0.089
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2263 1 1
Toxoplasma gondii AGC kinase 0.061 0.2298 0.2221
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0208 0.0423 0.0378
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0243 0.0584 0.0491
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0784 0.3108 0.3075
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0377 0.1213 0.1213
Echinococcus multilocularis calcium dependent protein kinase 0.0146 0.0133 0.0086
Schistosoma mansoni protein kinase 0.0472 0.1655 0.1655
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0342 0.1046 0.0957
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0187 0.0187
Trypanosoma cruzi casein kinase, putative 0.0233 0.0541 0.0541
Schistosoma mansoni serine/threonine protein kinase 0.0477 0.1677 0.1677
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0135 0.0083 0.0083
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0215 0.0455 0.0455
Trypanosoma cruzi casein kinase, putative 0.0233 0.0541 0.0541
Schistosoma mansoni protein kinase 0.0329 0.0986 0.0986
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0158 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0597 0.2237 0.2237
Trypanosoma cruzi NADH dehydrogenase, putative 0.0208 0.0423 0.0423
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0461 0.1604 0.1604
Entamoeba histolytica protein kinase, putative 0.0345 0.106 0.2829
Schistosoma mansoni nephrin related 0.0136 0.0086 0.0086
Plasmodium falciparum serine/threonine protein kinase, putative 0.0249 0.0612 0.0519
Echinococcus granulosus tyrosine protein kinase ABL1 0.0136 0.0085 0.0038
Toxoplasma gondii CMGC kinase, CK2 family 0.0215 0.0455 0.036
Brugia malayi Sushi domain 0.0422 0.1421 0.1421
Entamoeba histolytica protein kinase domain containing protein 0.0298 0.0844 0.2203
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0298 0.0844 0.0753
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0318 0.0934 0.089
Brugia malayi Protein kinase domain containing protein 0.0416 0.1392 0.1392
Schistosoma mansoni netrin receptor unc5 0.0136 0.0086 0.0086
Trichomonas vaginalis AGC family protein kinase 0.0361 0.1138 0.3661
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Loa Loa (eye worm) hypothetical protein 0.0208 0.0423 0.0423
Brugia malayi Temporarily assigned gene name protein 59 0.0277 0.0744 0.0744
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0505 0.1805 0.1766
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0263 0.0263
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.033 0.0991 0.0991
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0264 0.0684 0.064
Brugia malayi C1-like domain containing protein 0.0467 0.1631 0.1631
Brugia malayi Protein kinase domain containing protein 0.0646 0.2463 0.2463
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Echinococcus granulosus nephrin 0.0135 0.0083 0.0035
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0172 0.0255 0.0208
Echinococcus granulosus rho-associated protein kinase 1 0.0698 0.2707 0.2673
Brugia malayi glutamate synthase 0.0208 0.0423 0.0423
Schistosoma mansoni serine/threonine protein kinase 0.0175 0.0269 0.0269
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0208 0.0423 0.0423
Loa Loa (eye worm) TK protein kinase 0.019 0.0339 0.0339
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0138 0.0098 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0233 0.0541 0.0541
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0185 0.0314 0.0268
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0208 0.0423 0.0328
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0208 0.0423 0.0328
Echinococcus granulosus mitogen activated protein kinase 0.018 0.0291 0.0245
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0291 0.0937
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Entamoeba histolytica protein kinase , putative 0.0249 0.0612 0.1529
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0175 0.0269 0.0222
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0271 0.0715 0.0671
Loa Loa (eye worm) hypothetical protein 0.0253 0.0631 0.0631
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0083 0.0083
Onchocerca volvulus 0.0671 0.2579 0.7487
Brugia malayi SH2 domain containing protein 0.0136 0.0085 0.0085
Giardia lamblia Kinase, NEK 0.0292 0.0816 0.188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0083 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0803 0.0803
Leishmania major protein kinase A catalytic subunit 0.0243 0.0584 0.0491
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0351 0.1131
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.0423 0.0328
Plasmodium falciparum glutathione reductase 0.2263 1 1
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0757 0.2982 0.2948
Echinococcus granulosus casein kinase I delta 0.0233 0.0541 0.0495
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0136 0.0086 0.0038
Plasmodium falciparum protein kinase 5 0.0255 0.0642 0.0549
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0443 0.1519 0.1479
Brugia malayi Protein kinase domain containing protein 0.0295 0.0827 0.0827
Echinococcus multilocularis fat cadherin tumor suppressor 0.0229 0.0519 0.0474
Echinococcus granulosus defective proboscis extension response 0.0461 0.1604 0.1564
Schistosoma mansoni serine/threonine protein kinase 0.0464 0.1615 0.1615
Plasmodium vivax apical sushi protein, putative 0.0422 0.1421 0.1188
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0251 0.0625 0.0625
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0136 0.0086 0.0086
Brugia malayi Muscle positioning protein 4 0.0229 0.0519 0.0519
Onchocerca volvulus Serine\/threonine kinase homolog 0.058 0.2158 0.6256
Echinococcus multilocularis insulin receptor 0.0624 0.2361 0.2325
Echinococcus granulosus c4b binding protein beta chain 0.0422 0.1421 0.138
Echinococcus granulosus glutamate synthase 0.0208 0.0423 0.0378
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0163 0.0214 0.0214
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0083 0.0083
Leishmania major casein kinase, putative 0.0233 0.0541 0.0447
Echinococcus multilocularis Glutaredoxin protein 5 0.0266 0.0691 0.0647
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0381 0.123 0.1188
Onchocerca volvulus 0.0135 0.0081 0.0175
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0318 0.0934 0.089
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0208 0.0423 0.0328
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0584 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Brugia malayi serine/threonine-protein kinase 6 0.0249 0.0612 0.0612
Trichomonas vaginalis STE family protein kinase 0.0292 0.0816 0.2625
Loa Loa (eye worm) hypothetical protein 0.047 0.1642 0.1642
Onchocerca volvulus 0.0422 0.1421 0.4098
Entamoeba histolytica protein kinase, putative 0.0178 0.0285 0.0579
Giardia lamblia Kinase, AGC PKA 0.0243 0.0584 0.1061
Loa Loa (eye worm) hypothetical protein 0.0714 0.2779 0.2779
Onchocerca volvulus 0.0422 0.1421 0.4098
Brugia malayi Protein kinase domain containing protein 0.2023 0.8881 0.8881
Echinococcus granulosus basement membrane specific heparan sulfate 0.0136 0.0086 0.0038
Brugia malayi Protein kinase domain containing protein 0.0178 0.0285 0.0285
Brugia malayi serine/threonine-protein kinase PAK 7 0.0498 0.1776 0.1776
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0217 0.0462 0.0368
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0217 0.0462 0.0462
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0192 0.035 0.0304
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Leishmania major hypothetical protein, conserved 0.0208 0.0423 0.0328
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0472 0.1655 0.1615
Entamoeba histolytica protein kinase, putative 0.0219 0.0475 0.1131
Loa Loa (eye worm) CMGC/CLK protein kinase 0.033 0.0991 0.0991
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0271 0.0715 0.0671
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0266 0.0691 0.0647
Plasmodium falciparum serine/threonine protein kinase KIN 0.0166 0.0229 0.0131
Brugia malayi Serine/threonine-protein kinase SULU 0.0477 0.1677 0.1677
Echinococcus multilocularis tyrosine kinase 0.0136 0.0085 0.0038
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Echinococcus multilocularis serine:threonine protein kinase 0.0245 0.0595 0.055
Loa Loa (eye worm) hypothetical protein 0.0275 0.0737 0.0737
Onchocerca volvulus 0.0233 0.0541 0.1521
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0292 0.0816 0.0724
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0208 0.0423 0.0423
Entamoeba histolytica protein kinase, putative 0.0154 0.0172 0.0251
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0258 0.0656 0.0611
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0229 0.0519 0.1457
Entamoeba histolytica protein kinase, putative 0.0154 0.0172 0.0251
Schistosoma mansoni septate junction protein 0.0252 0.0628 0.0628
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0252 0.0628 0.1777
Brugia malayi RhoGAP domain containing protein 0.0158 0.0188 0.0188
Giardia lamblia Kinase, CMGC MAPK 0.018 0.0291 0.0022
Brugia malayi Hr1 repeat family protein 0.0623 0.2358 0.2358
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0127 0.0048 0.0048
Echinococcus granulosus roundabout 2 0.0271 0.0715 0.0671
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0741 0.2384
Onchocerca volvulus 0.0229 0.0519 0.1457
Brugia malayi basement membrane proteoglycan precursor 0.0136 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.0352 0.1095 0.1095
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0136 0.0086 0.0086
Echinococcus granulosus twitchin 0.0649 0.2477 0.2441
Brugia malayi cell division control protein 2 homolog 0.0255 0.0642 0.0642
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0249 0.0612 0.1529
Onchocerca volvulus 0.0413 0.1376 0.3968
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0229 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0243 0.0587 0.0587
Schistosoma mansoni tyrosine kinase 0.0429 0.1451 0.1451
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0605 0.1946
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0214 0.0214
Echinococcus multilocularis serine:threonine protein kinase 38 0.0345 0.106 0.1017
Echinococcus granulosus aurora kinase A 0.0249 0.0612 0.0567
Echinococcus multilocularis CDC7 cell division cycle 7 0.0193 0.0351 0.0305
Echinococcus granulosus notch 0.0229 0.0519 0.0474
Onchocerca volvulus 0.0422 0.1421 0.4098
Trichomonas vaginalis CAMK family protein kinase 0.0247 0.0605 0.1946
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Giardia lamblia Kinase, CMGC GSK 0.0276 0.0741 0.1616
Schistosoma mansoni cell adhesion molecule 0.0135 0.0083 0.0083
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0217 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.0136 0.0085 0.0085
Echinococcus granulosus Immunoglobulin 0.0136 0.0086 0.0038
Echinococcus granulosus cyclin dependent kinase 5 0.0255 0.0642 0.0597
Trichomonas vaginalis CAMK family protein kinase 0.058 0.2158 0.6944
Schistosoma mansoni serine/threonine protein kinase 0.0698 0.2707 0.2707
Schistosoma mansoni hypothetical protein 0.0135 0.0083 0.0083
Brugia malayi Protein kinase domain containing protein 0.1162 0.4867 0.4867
Echinococcus multilocularis mitogen activated protein kinase 11 0.0342 0.1046 0.1003
Loa Loa (eye worm) hypothetical protein 0.0243 0.0584 0.0584
Echinococcus multilocularis tyrosine protein kinase otk 0.0252 0.0628 0.0584
Trichomonas vaginalis STE family protein kinase 0.0185 0.0314 0.101
Schistosoma mansoni serine/threonine protein kinase 0.0437 0.1491 0.1491
Schistosoma mansoni cell adhesion molecule 0.0271 0.0715 0.0715
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0184 0.0312 0.0265
Trichomonas vaginalis CAMK family protein kinase 0.058 0.2158 0.6944
Loa Loa (eye worm) hypothetical protein 0.0136 0.0086 0.0086
Echinococcus multilocularis cyclin dependent kinase 5 0.0255 0.0642 0.0597
Echinococcus granulosus calcium dependent protein kinase 0.0146 0.0133 0.0086
Plasmodium falciparum calcium-dependent protein kinase 3 0.0217 0.0462 0.0368
Loa Loa (eye worm) hypothetical protein 0.0462 0.1607 0.1607
Schistosoma mansoni ste20-related kinase 0.044 0.1506 0.1506
Echinococcus granulosus ephrin type A receptor 4 A 0.0205 0.041 0.0364
Echinococcus multilocularis tyrosine protein kinase Abl 0.0195 0.0363 0.0317
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Echinococcus multilocularis glutamate synthase 0.0208 0.0423 0.0378
Schistosoma mansoni laminin gamma-3 chain 0.0229 0.0519 0.0519
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0461 0.1604 0.1564
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Entamoeba histolytica protein kinase domain containing protein 0.0138 0.0098 0.0038
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0208 0.0423 0.0423
Trypanosoma brucei casein kinase I, isoform 2 0.0233 0.0541 0.0447
Echinococcus granulosus nervana 2 0.0266 0.0691 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0548 0.2005 0.2005
Echinococcus multilocularis cyclin dependent kinase 9 0.0183 0.0305 0.0259
Giardia lamblia Kinase, CAMK CAMKL 0.0183 0.0307 0.0077
Echinococcus granulosus protein kinase 0.0329 0.0986 0.0943
Echinococcus multilocularis mitogen activated protein kinase 3 0.018 0.0291 0.0245
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Echinococcus granulosus tyrosine protein kinase Fyn 0.0318 0.0934 0.089
Entamoeba histolytica cell division protein kinase 2, putative 0.0255 0.0642 0.1617
Giardia lamblia Kinase, CMGC DYRK 0.0298 0.0844 0.1981
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0472 0.1655 0.1615
Plasmodium vivax calcium-dependent protein kinase, putative 0.0217 0.0462 0.0204
Loa Loa (eye worm) hypothetical protein 0.0184 0.0313 0.0313
Echinococcus multilocularis expressed conserved protein 0.0174 0.0263 0.0217
Brugia malayi Protein kinase domain containing protein 0.0193 0.0351 0.0351
Echinococcus multilocularis raf serine:threonine protein kinase 0.0158 0.0187 0.0141
Leishmania major casein kinase II, putative 0.0215 0.0455 0.036
Schistosoma mansoni glutamate synthase 0.0208 0.0423 0.0423
Schistosoma mansoni cell adhesion molecule 0.0252 0.0628 0.0628
Entamoeba histolytica protein kinase, putative 0.0178 0.0285 0.0579
Brugia malayi GCC2 and GCC3 family protein 0.0651 0.2487 0.2487
Brugia malayi Kinase associated domain 1 family protein 0.0219 0.0473 0.0473
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.024 0.0572 0.0527
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Trichomonas vaginalis STE family protein kinase 0.0138 0.0097 0.0312
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0243 0.0584 0.0491
Echinococcus multilocularis mitogen activated protein kinase 0.018 0.0291 0.0245
Entamoeba histolytica protein kinase, putative 0.0262 0.0677 0.1716
Brugia malayi EGF-like domain containing protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.3108
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0643 0.2448 0.2412
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0208 0.0423 0.0378
Brugia malayi protein kinase C3,putative 0.0339 0.1031 0.1031
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Entamoeba histolytica protein kinase, putative 0.0185 0.0314 0.0664
Echinococcus granulosus peroxidasin 0.0253 0.0631 0.0586
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0255 0.0642 0.0549
Entamoeba histolytica protein kinase domain containing protein 0.0435 0.1481 0.4052
Echinococcus granulosus casein kinase I alpha 0.0233 0.0541 0.0495
Schistosoma mansoni serine/threonine-protein kinase 0.0352 0.1096 0.1096
Loa Loa (eye worm) hypothetical protein 0.0136 0.0086 0.0086
Plasmodium falciparum thioredoxin reductase 0.2263 1 1
Loa Loa (eye worm) TK protein kinase 0.0375 0.1203 0.1203
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0217 0.0462 0.0417
Echinococcus granulosus dual specificity 0.0298 0.0844 0.08
Schistosoma mansoni tyrosine kinase 0.0429 0.1451 0.1451
Schistosoma mansoni c4b-binding protein beta chain 0.0422 0.1421 0.1421
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0715 0.0715
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0158 0.0188 0.0142
Echinococcus granulosus hypothetical protein 0.0259 0.0661 0.0617
Echinococcus multilocularis protein kinase c iota type 0.0613 0.2308 0.2272
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.033 0.0991 0.0991
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0318 0.0934 0.089
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.024 0.0572 0.0572
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0208 0.0423 0.0423
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0525 0.1902 0.1863
Echinococcus granulosus serine:threonine protein kinase N2 0.0278 0.0751 0.0707
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.3108
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0208 0.0423 0.0423
Schistosoma mansoni vesicular amine transporter 0.0461 0.1604 0.1604
Brugia malayi Cadherin domain containing protein 0.0229 0.0519 0.0519
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0208 0.0423 0.0328
Toxoplasma gondii casein kinase I 0.0233 0.0541 0.0447
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0345 0.106 0.1017
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0249 0.0612 0.1529
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.0263 0.0217
Echinococcus granulosus slit 2 protein 0.0275 0.0737 0.0693
Echinococcus granulosus contactin 0.0271 0.0715 0.0671
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0208 0.0423 0.0378
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0414 0.1383 0.1383
Brugia malayi Protein kinase domain containing protein 0.0136 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.024 0.0572 0.0572
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0318 0.0934 0.089
Entamoeba histolytica protein kinase domain containing protein 0.0166 0.0227 0.0412
Echinococcus granulosus activin receptor type 0.0138 0.0098 0.0051
Loa Loa (eye worm) TK/INSR protein kinase 0.0624 0.2361 0.2361
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0208 0.0423 0.0982
Echinococcus granulosus tyrosine protein kinase Src42A 0.0318 0.0934 0.089
Brugia malayi casein kinase I 0.0233 0.0541 0.0541
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0642 0.2066
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0262 0.0677 0.0584
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.0412 0.0412
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0477 0.1677 0.1637
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.1888 0.1888
Entamoeba histolytica protein kinase, putative 0.0249 0.0612 0.1529
Onchocerca volvulus 0.0137 0.0094 0.0213
Echinococcus granulosus casein kinase I alpha 0.0233 0.0541 0.0495
Brugia malayi Egg laying defective protein 4 0.0174 0.0263 0.0263
Echinococcus multilocularis roundabout 2 0.0732 0.2866 0.2832
Loa Loa (eye worm) hypothetical protein 0.0192 0.0347 0.0347
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0318 0.0934 0.089
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0083 0.0083
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0208 0.0423 0.1362
Echinococcus granulosus neurogenic locus notch protein 0.0229 0.0519 0.0474
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0136 0.0086 0.0038
Schistosoma mansoni cell adhesion molecule 0.0271 0.0715 0.0715
Echinococcus granulosus Immunoglobulin 0.0136 0.0086 0.0038
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0166 0.0229 0.0182
Trypanosoma cruzi casein kinase, putative 0.0233 0.0541 0.0541
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0784 0.3108 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0784 0.3108 0.3108
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0844 0.2716
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0757 0.2982 0.2982
Plasmodium falciparum calcium-dependent protein kinase 1 0.0217 0.0462 0.0368
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0525 0.1902 0.1902
Echinococcus multilocularis peroxidasin 0.0253 0.0631 0.0586
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0208 0.0423 0.0378
Echinococcus granulosus c src tyrosine kinase 0.0195 0.0363 0.0317
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0784 0.3108 0.2921
Trypanosoma cruzi cdc2-related kinase 3 0.0255 0.0642 0.0642
Schistosoma mansoni sulfide quinone reductase 0.0208 0.0423 0.0423
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0847 0.3399 0.3399
Echinococcus multilocularis cyclin 0.0862 0.3473 0.3442
Schistosoma mansoni cell adhesion molecule 0.0616 0.2323 0.2323
Trichomonas vaginalis CAMK family protein kinase 0.058 0.2158 0.6944
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.018 0.0291 0.0195
Trichomonas vaginalis CAMK family protein kinase 0.0466 0.1625 0.5228
Brugia malayi hypothetical protein 0.0477 0.1677 0.1677
Schistosoma mansoni protein kinase 0.0932 0.3796 0.3796
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0597 0.2237 0.2199
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0185 0.0314 0.0268
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0784 0.3108 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0285 0.0285
Brugia malayi Protein kinase domain containing protein 0.0133 0.0072 0.0072
Echinococcus granulosus neuroglian 0.0578 0.2147 0.2109
Loa Loa (eye worm) AGC/PKN protein kinase 0.0623 0.2358 0.2358
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0243 0.0584 0.0584
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0352 0.1092 0.1092
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0192 0.0346 0.0346
Trypanosoma brucei Casein kinase II 0.0215 0.0455 0.036
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0464 0.1615 0.1575
Echinococcus granulosus epidermal growth factor receptor 0.0707 0.2751 0.2716
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0208 0.0423 0.0423
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0477 0.1677 0.1677
Echinococcus multilocularis serine:threonine protein kinase N2 0.0623 0.2358 0.2321
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0271 0.0715 0.0715
Loa Loa (eye worm) notch protein 0.0229 0.0519 0.0519
Echinococcus granulosus tyrosine protein kinase Blk 0.0258 0.0656 0.0611
Echinococcus multilocularis hypothetical protein 0.0219 0.0473 0.0428
Brugia malayi Calcium binding EGF domain containing protein 0.0229 0.0519 0.0519
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0318 0.0934 0.089
Loa Loa (eye worm) hypothetical protein 0.0461 0.1604 0.1604
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0291 0.0937
Loa Loa (eye worm) hypothetical protein 0.0307 0.0883 0.0883
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0298 0.0844 0.0753
Schistosoma mansoni tyrosine kinase 0.0496 0.1767 0.1767
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1062 0.4401 0.4375
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0217 0.0462 0.0417
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0567 0.2098 0.2098
Echinococcus multilocularis 0.0259 0.0661 0.0617
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0715 0.2787 0.2787
Leishmania major protein kinase, putative 0.0217 0.0462 0.0368
Loa Loa (eye worm) hypothetical protein 0.0643 0.2449 0.2449
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0249 0.0612 0.0567
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0381 0.123 0.1188
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0643 0.2448 0.2412
Echinococcus multilocularis slit 2 protein 0.0275 0.0737 0.0693
Echinococcus granulosus dual specificity 0.0262 0.0677 0.0632
Echinococcus multilocularis dual specificity 0.0298 0.0844 0.08
Plasmodium vivax serine/threonine kinase-1, putative 0.033 0.0991 0.0747
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0784 0.3108 0.304
Echinococcus multilocularis myosin iiia 0.0182 0.03 0.0254
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Echinococcus granulosus nervana 2 0.0266 0.0691 0.0647
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0217 0.0462 0.0417
Brugia malayi Cadherin domain containing protein 0.0229 0.0519 0.0519
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0784 0.3108 1
Schistosoma mansoni hypothetical protein 0.0229 0.0519 0.0519
Echinococcus multilocularis cyclin dependent kinase 1 0.0255 0.0642 0.0597
Echinococcus multilocularis NCK adaptor protein 0.013 0.0057 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.0136 0.0086 0.0086
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0381 0.123 0.1188
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0352 0.1095 0.1095
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0208 0.0423 0.0328
Entamoeba histolytica serine/threonine protein kinase, putative 0.058 0.2158 0.6017
Toxoplasma gondii NADPH-glutathione reductase 0.0784 0.3108 0.304
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0788 0.3124 0.3124
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Echinococcus multilocularis nervana 2 0.0266 0.0691 0.0647
Echinococcus granulosus low density lipoprotein receptor ldl 0.0136 0.0086 0.0038
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0784 0.3108 0.2921
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0467 0.1631 0.1631
Loa Loa (eye worm) hypothetical protein 0.0166 0.0229 0.0229
Schistosoma mansoni peroxidasin 0.0136 0.0088 0.0088
Echinococcus granulosus serine:threonine protein kinase PLK1 0.058 0.2158 0.2121
Loa Loa (eye worm) hypothetical protein 0.0135 0.0083 0.0083
Brugia malayi Immunoglobulin I-set domain containing protein 0.0206 0.0412 0.0412
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0498 0.1775 0.1735
Onchocerca volvulus 0.0136 0.0085 0.0187
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0784 0.3108 0.3108
Schistosoma mansoni tyrosine kinase 0.0195 0.0363 0.0363
Brugia malayi Protein kinase domain containing protein 0.0365 0.1157 0.1157
Echinococcus multilocularis dual specificity 0.0262 0.0677 0.0632
Brugia malayi P38 map kinase family protein 2 0.0342 0.1046 0.1046
Entamoeba histolytica protein kinase, putative 0.0138 0.0097 0.0034
Echinococcus multilocularis mitogen activated protein kinase 14 0.0342 0.1046 0.1003
Brugia malayi EGF-like domain containing protein 0.0229 0.0519 0.0519
Schistosoma mansoni protein kinase 0.0569 0.2104 0.2104
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0498 0.1776 0.1776
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0267 0.07 0.0607
Brugia malayi Temporarily assigned gene name protein 59 0.024 0.0572 0.0572
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0784 0.3108 0.3075
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0461 0.1604 0.1604
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.033 0.0991 0.0901
Echinococcus granulosus protein kinase shaggy 0.0276 0.0741 0.0697
Echinococcus multilocularis casein kinase I delta 0.0233 0.0541 0.0495
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0496 0.1767 0.1727
Loa Loa (eye worm) hypothetical protein 0.0498 0.1775 0.1775
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0136 0.0086 0.0038
Entamoeba histolytica protein kinase, putative 0.0249 0.0612 0.1529
Echinococcus granulosus titin 0.0206 0.0412 0.0367
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0229 0.0229
Schistosoma mansoni cell adhesion molecule 0.0135 0.0083 0.0083
Schistosoma mansoni serine/threonine kinase 0.0345 0.106 0.106
Echinococcus granulosus CDC7 cell division cycle 7 0.0193 0.0351 0.0305
Echinococcus granulosus serine:threonine protein kinase 0.0245 0.0595 0.055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0136 0.0086 0.0086
Trypanosoma cruzi polo-like protein kinase, putative 0.058 0.2158 0.2158
Echinococcus multilocularis Immunoglobulin 0.0461 0.1604 0.1564
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Plasmodium falciparum casein kinase 2, alpha subunit 0.0215 0.0455 0.036
Brugia malayi Protein kinase domain containing protein 0.0262 0.0677 0.0677
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0048 0.0048
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0847 0.3399 0.3367
Echinococcus granulosus serine:threonine protein kinase N2 0.0623 0.2358 0.2321
Echinococcus multilocularis c4b binding protein beta chain 0.0422 0.1421 0.138
Toxoplasma gondii AGC kinase 0.0243 0.0584 0.0491
Schistosoma mansoni protein kinase 0.0414 0.1383 0.1383
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0788 0.3124 0.3091
Trichomonas vaginalis glutamate synthase, putative 0.0208 0.0423 0.1362
Entamoeba histolytica protein kinase, putative 0.0217 0.0462 0.1095
Trypanosoma cruzi cdc2-related kinase 1 0.0255 0.0642 0.0642
Echinococcus multilocularis casein kinase i 0.0233 0.0541 0.0495
Trichomonas vaginalis AGC family protein kinase 0.0382 0.1232 0.3962
Trichomonas vaginalis CMGC family protein kinase 0.033 0.0991 0.3188
Giardia lamblia Kinase, CMGC CDK 0.0255 0.0642 0.1266
Treponema pallidum NADH oxidase 0.0784 0.3108 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0784 0.3108 0.3108
Brugia malayi EGF-like domain containing protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) hypothetical protein 0.0252 0.0628 0.0628
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Schistosoma mansoni tyrosine kinase 0.0352 0.1095 0.1095
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0233 0.0541 0.0541
Echinococcus multilocularis cyclin dependent kinase 19 0.1162 0.4867 0.4842
Echinococcus granulosus fibroblast growth factor receptor 4 0.0381 0.123 0.1188
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.1095 0.1095
Schistosoma mansoni tyrosine kinase 0.0429 0.1451 0.1451
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0642 0.0642
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.024 0.0572 0.0527
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0158 0.0188 0.0188
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0183 0.0307 0.0044
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0166 0.0229 0.0131
Echinococcus multilocularis lachesin 0.0252 0.0628 0.0584
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0159 0.0192 0.0192
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0757 0.2982 0.8668
Toxoplasma gondii EGF family domain-containing protein 0.0229 0.0519 0.0425
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0423 0.0423
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0185 0.0314 0.0268
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0208 0.0423 0.0378
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0276 0.0741 0.0649
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0255 0.0642 0.0597
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0276 0.0741 0.0741
Plasmodium vivax thioredoxin reductase, putative 0.2263 1 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0318 0.0934 0.089
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0255 0.0642 0.0642
Brugia malayi Immunoglobulin I-set domain containing protein 0.0252 0.0628 0.0628
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0345 0.106 0.1017
Brugia malayi serine/threonine kinase 12 0.0249 0.0612 0.0612
Entamoeba histolytica PH domain containing protein kinase, putative 0.0259 0.0659 0.1666
Brugia malayi Protein kinase domain containing protein 0.0458 0.1587 0.1587
Trichomonas vaginalis AGC family protein kinase 0.0249 0.0612 0.1969
Schistosoma mansoni titin 0.0135 0.0083 0.0083
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0298 0.0844 0.0753
Echinococcus multilocularis neurogenic locus notch protein 4 0.0229 0.0519 0.0474
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0352 0.1095 0.1053
Plasmodium falciparum calcium-dependent protein kinase 2 0.0217 0.0462 0.0368
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0208 0.0423 0.1362
Loa Loa (eye worm) hypothetical protein 0.0397 0.1302 0.1302
Entamoeba histolytica protein kinase domain containing protein 0.0276 0.0741 0.1903
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Echinococcus granulosus Immunoglobulin subtype 0.0136 0.0086 0.0038
Echinococcus granulosus neural cadherin 0.0229 0.0519 0.0474
Trypanosoma cruzi casein kinase, putative 0.0233 0.0541 0.0541
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0784 0.3108 0.304
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0135 0.0083 0.0083
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0784 0.3108 0.304
Brugia malayi serine/threonine protein kinase 6 0.0249 0.0612 0.0612
Trypanosoma cruzi casein kinase, putative 0.0233 0.0541 0.0541
Loa Loa (eye worm) TK protein kinase 0.0258 0.0656 0.0656
Schistosoma mansoni nephrin 0.0271 0.0715 0.0715
Trichomonas vaginalis apoptosis inducing factor, putative 0.0208 0.0423 0.1362
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.0263 0.0217
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.3108
Echinococcus granulosus serine/threonine protein kinase 0.0352 0.1096 0.1053
Echinococcus granulosus casein kinase ii subunit alpha 0.0215 0.0455 0.041
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0803 0.0803
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0342 0.1046 0.0957
Echinococcus granulosus Protein kinase C brain isozyme 0.0522 0.1888 0.1849
Giardia lamblia Kinase, CMGC CLK 0.033 0.0991 0.2501
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0298 0.0844 0.0844
Giardia lamblia Kinase, CAMK CAMKL 0.0183 0.0307 0.0077
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0136 0.0086 0.0086
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0276 0.0741 0.0697
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0243 0.0584 0.0584
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0208 0.0423 0.0378
Schistosoma mansoni tyrosine kinase 0.0284 0.0778 0.0778
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0351 0.0351
Onchocerca volvulus Slit protein homolog 0.0275 0.0737 0.2095
Trichomonas vaginalis AGC family protein kinase 0.0365 0.1157 0.3721
Echinococcus granulosus Immunoglobulin 0.0461 0.1604 0.1564
Entamoeba histolytica PH domain containing protein kinase, putative 0.0259 0.0659 0.1666
Echinococcus multilocularis epidermal growth factor receptor 0.0707 0.2751 0.2716
Echinococcus multilocularis protein jagged 2 0.0229 0.0519 0.0474
Brugia malayi Casein kinase II, alpha chain 0.0215 0.0455 0.0455
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0435 0.1481 0.144
Leishmania major protein kinase, putative 0.033 0.0991 0.0901
Echinococcus granulosus calcium activated potassium channel 0.029 0.0803 0.0759
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Brugia malayi Immunoglobulin I-set domain containing protein 0.0271 0.0715 0.0715
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0227 0.0227
Schistosoma mansoni serine/threonine protein kinase 0.033 0.0991 0.0991
Echinococcus multilocularis neurogenic locus protein delta 0.0229 0.0519 0.0474
Trichomonas vaginalis CMGC family protein kinase 0.0215 0.0455 0.1464
Entamoeba histolytica serine/threonine protein kinase, putative 0.0166 0.0229 0.0416
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Brugia malayi Immunoglobulin I-set domain containing protein 0.0252 0.0628 0.0628
Onchocerca volvulus 0.0136 0.0085 0.0187
Loa Loa (eye worm) hypothetical protein 0.024 0.0572 0.0572
Echinococcus multilocularis serine:threonine protein kinase 0.0245 0.0595 0.055
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0229 0.0519 0.0519
Loa Loa (eye worm) CDC7 protein kinase 0.0193 0.0351 0.0351
Onchocerca volvulus 0.0229 0.0519 0.1457
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.304
Brugia malayi Cam kinase protein 1 0.0217 0.0462 0.0462
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0136 0.0086 0.0038
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0208 0.0423 0.1362
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0208 0.0423 0.0982
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0175 0.0269 0.0269
Brugia malayi Delta serrate ligand family protein 0.0229 0.0519 0.0519
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0172 0.0172
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0208 0.0423 0.0328
Brugia malayi serine/threonine-protein kinase plk-2 0.058 0.2158 0.2158
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0136 0.0085 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.1162 0.4867 0.4867
Loa Loa (eye worm) hypothetical protein 0.0252 0.0628 0.0628
Entamoeba histolytica cell division protein kinase 2, putative 0.0272 0.072 0.1843
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0249 0.0612 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0597 0.2236 0.7195
Plasmodium falciparum apical sushi protein 0.0422 0.1421 0.1336
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0318 0.0934 0.089
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0243 0.0584 0.0584
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0208 0.0423 0.1362
Brugia malayi protein-tyrosine kinase 0.0258 0.0656 0.0656
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0243 0.0584 0.0491
Entamoeba histolytica protein kinase domain containing protein 0.0276 0.0741 0.1903
Brugia malayi hypothetical protein 0.024 0.0572 0.0572
Echinococcus multilocularis neuroglian 0.0578 0.2147 0.2109
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0342 0.1046 0.1046
Trichomonas vaginalis glutathione reductase, putative 0.0784 0.3108 1
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0178 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0714 0.2779 0.2779
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Trypanosoma cruzi casein kinase II, putative 0.0215 0.0455 0.0455
Trichomonas vaginalis STE family protein kinase 0.0182 0.03 0.0966
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0208 0.0423 0.0378
Loa Loa (eye worm) hypothetical protein 0.0252 0.0628 0.0628
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0757 0.2982 0.2982
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0178 0.0285 0.0188
Giardia lamblia Kinase, CMGC CDK 0.0255 0.0642 0.1266
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0182 0.03 0.0204
Loa Loa (eye worm) hypothetical protein 0.0252 0.0628 0.0628
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0217 0.0462 0.0204
Echinococcus multilocularis protein tyrosine kinase 0.0581 0.2161 0.2124
Brugia malayi probable protein kinase 0.0569 0.2104 0.2104
Brugia malayi protein kinase C II. 0.0437 0.1491 0.1491
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0462 0.0462
Giardia lamblia Kinase, CDC7 0.0193 0.0351 0.0236
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0271 0.0715 0.0671
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0342 0.1046 0.1046
Loa Loa (eye worm) programmed cell death 8 0.0208 0.0423 0.0423
Trichomonas vaginalis CAMK family protein kinase 0.058 0.2158 0.6944
Echinococcus multilocularis protein kinase c epsilon type 0.0437 0.1491 0.1451
Echinococcus granulosus Vam6:Vps39 protein 0.024 0.0572 0.0527
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.0595 0.1915
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0158 0.0188 0.0142
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Brugia malayi Heparan sulfate 0.0136 0.0086 0.0086
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0208 0.0423 0.0328
Giardia lamblia Kinase, CK1 Casein kinase 0.0233 0.0541 0.0906
Schistosoma mansoni serine/threonine protein kinase 0.0525 0.1902 0.1902
Schistosoma mansoni hypothetical protein 0.0136 0.0086 0.0086
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0233 0.0541 0.0541
Entamoeba histolytica hypothetical protein 0.0262 0.0677 0.1716
Brugia malayi Stress-activated protein kinase jnk-1 0.0567 0.2098 0.2098
Trichomonas vaginalis CMGC family protein kinase 0.0255 0.0642 0.2066
Trypanosoma brucei trypanothione reductase 0.2263 1 1
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0422 0.1421 0.1421
Brugia malayi Fibronectin type III domain containing protein 0.048 0.1691 0.1691
Giardia lamblia Kinase, CMGC CK2 0.0215 0.0455 0.0603
Echinococcus granulosus cyclin dependent kinase 19 0.1162 0.4867 0.4842
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0208 0.0423 0.0378
Plasmodium falciparum glycogen synthase kinase 3 0.0276 0.0741 0.0649
Schistosoma mansoni tyrosine kinase 0.0195 0.0363 0.0363
Plasmodium falciparum calcium-dependent protein kinase 4 0.0217 0.0462 0.0368
Echinococcus multilocularis calcium activated potassium channel 0.029 0.0803 0.0759
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0311 0.0903 0.0859
Brugia malayi Immunoglobulin I-set domain containing protein 0.0252 0.0628 0.0628
Trypanosoma cruzi polo-like protein kinase, putative 0.058 0.2158 0.2158
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.018 0.0291 0.0195
Plasmodium falciparum NIMA related kinase 1 0.0292 0.0816 0.0724
Trypanosoma brucei rac serine-threonine kinase, putative 0.0626 0.2373 0.2297
Giardia lamblia NADH oxidase lateral transfer candidate 0.0784 0.3108 1
Echinococcus granulosus tyrosine protein kinase 0.0311 0.0902 0.0859
Onchocerca volvulus 0.0135 0.0083 0.018
Echinococcus granulosus casein kinase I delta 0.0233 0.0541 0.0495
Echinococcus granulosus tyrosine protein kinase HCK 0.019 0.0339 0.0293
Echinococcus multilocularis notch 0.0229 0.0519 0.0474
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.018 0.0291 0.0195
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Echinococcus granulosus tyrosine kinase 0.0258 0.0656 0.0611
Brugia malayi Protein kinase domain containing protein 0.0624 0.2361 0.2361
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0208 0.0423 0.0328
Loa Loa (eye worm) hypothetical protein 0.0135 0.0083 0.0083
Echinococcus multilocularis roundabout 2 0.0271 0.0715 0.0671
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0684 0.0684
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0217 0.0462 0.0368
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0135 0.0083 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0498 0.1772 0.1772
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0208 0.0423 0.0378
Loa Loa (eye worm) TK/FER protein kinase 0.0443 0.1519 0.1519
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0233 0.0541 0.0541
Onchocerca volvulus 0.0397 0.1302 0.3748
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0646 0.2463 0.2463
Leishmania major protein kinase A catalytic subunit isoform 1 0.0243 0.0584 0.0491
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0324 0.0963 0.0963
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0576 0.2138 0.2138
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Echinococcus multilocularis C type lectin domian containing protein 0.0422 0.1421 0.138
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0174 0.0264 0.0167
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.058 0.2158 0.2121
Echinococcus multilocularis twitchin 0.0187 0.0326 0.028
Brugia malayi casein kinase 1, delta 0.0233 0.0541 0.0541
Echinococcus multilocularis titin 0.0206 0.0412 0.0367
Entamoeba histolytica protein kinase 2, putative 0.0336 0.1021 0.2716
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0255 0.0642 0.0642
Echinococcus multilocularis expressed protein 0.0178 0.0285 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0505 0.1805 0.1805
Echinococcus multilocularis ephrin type A receptor 4 A 0.0205 0.041 0.0364
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Echinococcus granulosus serine:threonine protein kinase 0.0245 0.0595 0.055
Brugia malayi Protein kinase domain containing protein 0.0587 0.219 0.219
Toxoplasma gondii selenide, water dikinase 0.0208 0.0423 0.0328
Trichomonas vaginalis AGC family protein kinase 0.0175 0.0269 0.0864
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0552 0.2024 0.2024
Brugia malayi Protein kinase domain containing protein 0.0431 0.1462 0.1462
Trypanosoma brucei polo-like protein kinase 0.058 0.2158 0.208
Entamoeba histolytica p21-activated kinase 0.0201 0.0389 0.0882
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1525 0.656 0.6544
Echinococcus granulosus netrin receptor unc 5 0.0198 0.0375 0.0329
Loa Loa (eye worm) SRC-1 0.0318 0.0934 0.0934
Onchocerca volvulus 0.0422 0.1421 0.4098
Loa Loa (eye worm) thioredoxin reductase 0.2263 1 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0195 0.0363 0.0363
Echinococcus multilocularis casein kinase I delta 0.0233 0.0541 0.0495
Brugia malayi basement membrane proteoglycan 0.0136 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.024 0.0572 0.0572
Brugia malayi ephrin receptor 1 precursor 0.0132 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.048 0.1691 0.1691
Entamoeba histolytica protein kinase, putative 0.0175 0.0269 0.0532
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0341 0.1045 0.1045
Onchocerca volvulus Neurogenic locus notch homolog 0.0229 0.0519 0.1457
Echinococcus granulosus protein jagged 1 0.0229 0.0519 0.0474
Schistosoma mansoni notch 0.0229 0.0519 0.0519
Brugia malayi Variant SH3 domain containing protein 0.0127 0.0048 0.0048
Plasmodium falciparum calcium-dependent protein kinase 5 0.0217 0.0462 0.0368
Brugia malayi hypothetical protein 0.048 0.1691 0.1691
Loa Loa (eye worm) AUR protein kinase 0.0249 0.0612 0.0612
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Schistosoma mansoni roundabout 0.0252 0.0628 0.0628
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.0263 0.0217
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0208 0.0423 0.1362
Schistosoma mansoni tyrosine kinase 0.0707 0.2751 0.2751
Brugia malayi EGF-like domain containing protein 0.0275 0.0737 0.0737
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0174 0.0264 0.0167
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0844 0.2716
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0139 0.0099 0.0041
Schistosoma mansoni tyrosine kinase 0.0318 0.0934 0.0934
Leishmania major protein kinase, putative 0.0249 0.0612 0.0519
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0178 0.0285 0.0188
Loa Loa (eye worm) hypothetical protein 0.0136 0.0086 0.0086
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0182 0.03 0.03
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0208 0.0423 0.0378
Onchocerca volvulus 0.0422 0.1421 0.4098
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Leishmania major hypothetical protein, conserved 0.0208 0.0423 0.0328
Echinococcus granulosus mitogen activated protein kinase 11 0.0342 0.1046 0.1003
Schistosoma mansoni protein kinase 0.0932 0.3796 0.3796
Brugia malayi Protein kinase domain containing protein 0.0136 0.0085 0.0085
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0336 0.1021 0.0777
Brugia malayi Immunoglobulin domain containing protein 0.0136 0.0086 0.0086
Schistosoma mansoni nephrin 0.0597 0.2234 0.2234
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.0263 0.0217
Trichomonas vaginalis AGC family protein kinase 0.0626 0.2373 0.7634
Echinococcus granulosus delta-like protein 1 0.0229 0.0519 0.0474
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0477 0.1677 0.1637
Echinococcus multilocularis casein kinase I gamma 0.0458 0.1587 0.1547
Echinococcus granulosus tyrosine protein kinase Src42A 0.0192 0.035 0.0304
Echinococcus multilocularis dual specificity 0.0298 0.0844 0.08
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0208 0.0423 0.0328
Echinococcus multilocularis neurogenic locus protein delta 0.0229 0.0519 0.0474
Trichomonas vaginalis CK1 family protein kinase 0.0233 0.0541 0.1739
Schistosoma mansoni serine/threonine-protein kinase 0.0352 0.1096 0.1096
Schistosoma mansoni protein kinase 0.0185 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0298 0.0842 0.0842
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0318 0.0934 0.089
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0291 0.0291
Brugia malayi Protein kinase domain containing protein 0.0175 0.0269 0.0269
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1062 0.4401 0.4375
Trichomonas vaginalis CAMK family protein kinase 0.0271 0.0718 0.231
Schistosoma mansoni tyrosine kinase 0.032 0.0944 0.0944
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0345 0.106 0.1017
Brugia malayi Thioredoxin reductase 0.2263 1 1
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0136 0.0086 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Schistosoma mansoni serine/threonine kinase 0.0483 0.1703 0.1703
Loa Loa (eye worm) TK/FER protein kinase 0.0136 0.0085 0.0085
Brugia malayi putative serine/threonine kinase SADA gamma 0.0166 0.0229 0.0229
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0243 0.0584 0.0539
Echinococcus multilocularis casein kinase I alpha 0.0233 0.0541 0.0495
Schistosoma mansoni protein kinase 0.0215 0.0455 0.0455
Echinococcus multilocularis aurora kinase A 0.0249 0.0612 0.0567
Loa Loa (eye worm) hypothetical protein 0.0255 0.0644 0.0644
Schistosoma mansoni ephrin receptor 0.0205 0.041 0.041
Echinococcus granulosus lachesin 0.0252 0.0628 0.0584
Schistosoma mansoni rap gtpase-activating protein 0.024 0.0572 0.0572
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0138 0.0098 0.0098
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0784 0.3108 1
Brugia malayi p70 ribosomal S6 kinase beta 0.061 0.2298 0.2298
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0784 0.3108 0.3108
Plasmodium falciparum protein serine/threonine kinase-1 0.033 0.0991 0.0901
Loa Loa (eye worm) hypothetical protein 0.0422 0.1421 0.1421
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0431 0.1462 0.1462
Loa Loa (eye worm) AUR protein kinase 0.0249 0.0612 0.0612
Entamoeba histolytica protein kinase, putative 0.0262 0.0677 0.1716
Loa Loa (eye worm) hypothetical protein 0.0217 0.0462 0.0462
Echinococcus multilocularis Immunoglobulin subtype 0.0136 0.0086 0.0038
Loa Loa (eye worm) LAD-2 short isoform 0.0136 0.0086 0.0086
Onchocerca volvulus Putative cubilin 0.0229 0.0519 0.1457
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0215 0.0455 0.0196
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0784 0.3108 0.304
Schistosoma mansoni netrin receptor unc5 0.0198 0.0375 0.0375
Onchocerca volvulus 0.0206 0.0412 0.1145
Entamoeba histolytica casein kinase, putative 0.0233 0.0541 0.1322
Onchocerca volvulus 0.0229 0.0519 0.1457
Onchocerca volvulus 0.0229 0.0519 0.1457
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0361 0.0361
Echinococcus multilocularis casein kinase I alpha 0.0233 0.0541 0.0495
Echinococcus multilocularis tyrosine protein kinase HCK 0.019 0.0339 0.0293
Onchocerca volvulus 0.0307 0.0883 0.2523
Brugia malayi Protein kinase domain containing protein 0.0136 0.0085 0.0085
Echinococcus multilocularis Immunoglobulin 0.0461 0.1604 0.1564
Onchocerca volvulus 0.0422 0.1421 0.4098
Brugia malayi SRC-1 0.0318 0.0934 0.0934
Loa Loa (eye worm) AGC/NDR protein kinase 0.0345 0.106 0.106
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0166 0.0229 0.0229
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0329 0.0986 0.0986
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.033 0.0991 0.0991
Echinococcus multilocularis tyrosine protein kinase Srms 0.0258 0.0656 0.0611
Brugia malayi Furin-like cysteine rich region family protein 0.0707 0.2751 0.2751
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0217 0.0462 0.0417
Giardia lamblia Kinase, NEK 0.0292 0.0816 0.188
Echinococcus granulosus serine threonine protein kinase nrc 0.0336 0.1021 0.0978
Echinococcus multilocularis Immunoglobulin 0.0136 0.0086 0.0038
Echinococcus multilocularis protein kinase shaggy 0.0276 0.0741 0.0697
Loa Loa (eye worm) TK protein kinase 0.0498 0.1772 0.1772
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0233 0.0541 0.0541
Echinococcus multilocularis mitogen activated protein kinase 14 0.0342 0.1046 0.1003
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0229 0.0229
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0172 0.0172
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0757 0.2982 0.2948
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0217 0.0462 0.0417
Loa Loa (eye worm) hypothetical protein 0.0229 0.0519 0.0519
Schistosoma mansoni kinase 0.062 0.2343 0.2343
Echinococcus granulosus serine:threonine kinase SAD 1 0.0166 0.0229 0.0182
Loa Loa (eye worm) hypothetical protein 0.0175 0.0269 0.0269
Loa Loa (eye worm) TK protein kinase 0.0311 0.0902 0.0902
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0264 0.0684 0.0684
Trichomonas vaginalis CMGC family protein kinase 0.0276 0.0741 0.2384
Loa Loa (eye worm) protein kinase domain-containing protein 0.0458 0.1587 0.1587
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1335 0.5677 0.5677
Trichomonas vaginalis CAMK family protein kinase 0.058 0.2158 0.6944
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0166 0.0229 0.0131
Brugia malayi pregnancy-associated plasma protein-A 0.0422 0.1421 0.1421
Schistosoma mansoni serine/threonine protein kinase 0.1024 0.4227 0.4227
Echinococcus granulosus cyclin dependent kinase 0.0255 0.0642 0.0597
Schistosoma mansoni septate junction protein 0.0136 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0271 0.0715 0.0715
Loa Loa (eye worm) hypothetical protein 0.0651 0.2487 0.2487
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0249 0.0612 0.1529
Brugia malayi Protein kinase domain containing protein 0.0788 0.3124 0.3124
Schistosoma mansoni disulfide oxidoreductase 0.0208 0.0423 0.0423
Onchocerca volvulus Serine\/threonine kinase homolog 0.0352 0.1095 0.3145
Echinococcus multilocularis rho associated protein kinase 0.0698 0.2707 0.2673
Echinococcus granulosus hemicentin 1 0.0252 0.0628 0.0584
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.1888 0.1888
Echinococcus granulosus roundabout 2 0.0271 0.0715 0.0671
Toxoplasma gondii rhoptry neck protein RON9 0.0422 0.1421 0.1336
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0351 0.1131
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0243 0.0584 0.0491
Schistosoma mansoni glutamate synthase 0.0208 0.0423 0.0423
Brugia malayi Protein kinase c protein 2 0.0248 0.0611 0.0611
Echinococcus granulosus protein kinase c iota type 0.0613 0.2308 0.2272
Onchocerca volvulus 0.0163 0.0211 0.0556
Schistosoma mansoni protein kinase 0.0185 0.0314 0.0314
Schistosoma mansoni serine/threonine protein kinase 0.0757 0.2982 0.2982
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0208 0.0423 0.0164
Mycobacterium tuberculosis Probable oxidoreductase 0.0784 0.3108 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0229 0.0229
Loa Loa (eye worm) TK/EGFR protein kinase 0.0707 0.2751 0.2751
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0932 0.3796 0.3767
Loa Loa (eye worm) hypothetical protein 0.0298 0.0842 0.0842
Loa Loa (eye worm) projectin 0.0135 0.0083 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0623 0.2358 0.2358
Echinococcus granulosus thioredoxin glutathione reductase 0.2263 1 1
Loa Loa (eye worm) hypothetical protein 0.048 0.1691 0.1691
Schistosoma mansoni hypothetical protein 0.0136 0.0086 0.0086
Schistosoma mansoni cell polarity protein 0.0229 0.0519 0.0519
Trichomonas vaginalis CMGC family protein kinase 0.0298 0.0844 0.2716
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0646 0.2463 0.2463
Entamoeba histolytica disulphide oxidoreductase, putative 0.0208 0.0423 0.0982
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0208 0.0423 0.0378
Echinococcus granulosus NDR protein kinase 0.0345 0.106 0.1017
Echinococcus multilocularis protein jagged 1 0.0229 0.0519 0.0474
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0243 0.0584 0.0584
Schistosoma mansoni myosin-binding protein-related 0.0135 0.0083 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.018 0.0291 0.0937
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0166 0.0227 0.0227
Brugia malayi hypothetical protein 0.0422 0.1421 0.1421
Brugia malayi Protein kinase domain containing protein 0.0245 0.0595 0.0595
Echinococcus multilocularis casein kinase ii subunit alpha 0.0215 0.0455 0.041
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0525 0.1902 0.1863
Schistosoma mansoni sulfide quinone reductase 0.0208 0.0423 0.0423
Echinococcus granulosus cyclin dependent kinase 9 0.0166 0.0227 0.0181
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0435 0.1481 0.1481
Trichomonas vaginalis CK1 family protein kinase 0.0233 0.0541 0.1739
Trichomonas vaginalis CAMK family protein kinase 0.0166 0.0229 0.0736
Echinococcus granulosus tyrosine protein kinase Lyn 0.0388 0.1263 0.1222
Plasmodium vivax serine/threonine protein kinase, putative 0.0178 0.0285 0.0021
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0576 0.2138 0.2138
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0352 0.1095 0.1053
Trichomonas vaginalis CK1 family protein kinase 0.0233 0.0541 0.1739
Leishmania major protein kinase, putative 0.0182 0.03 0.0204
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0258 0.0656 0.0611
Schistosoma mansoni growth factor receptor-bound protein 0.0127 0.0048 0.0048
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0166 0.0229 0.0229
Brugia malayi STE20-like kinase MST 0.0552 0.2024 0.2024
Schistosoma mansoni cell adhesion molecule 0.0136 0.0086 0.0086
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0423 0.0423
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0567 0.2098 0.206
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0435 0.1481 0.1481
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0208 0.0423 0.1362
Trichomonas vaginalis AGC family protein kinase 0.0243 0.0584 0.188
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0784 0.3108 0.304
Schistosoma mansoni serine/threonine protein kinase 0.0505 0.1805 0.1805
Echinococcus granulosus dual specificity protein kinase clk2 0.033 0.0991 0.0948

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 10 nM Inhibitory concentration against Vascular endothelial growth factor receptor 2 ChEMBL. 15713401
IC50 (binding) = 10 nM Inhibitory concentration against Vascular endothelial growth factor receptor 2 ChEMBL. 15713401

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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