Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-C motif) receptor 3 | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 145 nM | In vitro binding affinity of the compound against C-C chemokine receptor type 3 expressing in rat Y3 cell line | ChEMBL. | 15713390 |
Ki (binding) | = 145 nM | In vitro binding affinity of the compound against C-C chemokine receptor type 3 expressing in rat Y3 cell line | ChEMBL. | 15713390 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.