Detailed information for compound 315027

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 972.137 | Formula: C43H77N11O14
  • H donors: 14 H acceptors: 14 LogP: -4.09 Rotable bonds: 40
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)[C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](CC(=O)N)N)CC(C)C)CCC(=O)N)CC(C)C)C)C
  • InChi: 1S/C43H77N11O14/c1-11-21(7)32(40(64)51-29(18-55)43(67)68)53-41(65)33(22(8)12-2)52-35(59)23(9)47-38(62)27(15-19(3)4)49-37(61)26(13-14-30(45)57)48-39(63)28(16-20(5)6)50-42(66)34(24(10)56)54-36(60)25(44)17-31(46)58/h19-29,32-34,55-56H,11-18,44H2,1-10H3,(H2,45,57)(H2,46,58)(H,47,62)(H,48,63)(H,49,61)(H,50,66)(H,51,64)(H,52,59)(H,53,65)(H,54,60)(H,67,68)/t21-,22-,23-,24+,25-,26-,27-,28-,29-,32-,33-,34-/m0/s1
  • InChiKey: NBWSFZDQGSVOCT-TXWBMCNGSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) projectin 0.0148 0.0116 0.0116
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0249 0.0507 0.0507
Brugia malayi Protein kinase domain containing protein 0.0563 0.1718 0.1718
Loa Loa (eye worm) hypothetical protein 0.0276 0.0611 0.0611
Trypanosoma brucei NADH dehydrogenase 0.0249 0.0507 0.0482
Schistosoma mansoni c4b-binding protein beta chain 0.0506 0.1496 0.1496
Plasmodium vivax glutathione reductase, putative 0.2711 1 1
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0296 0.0685 0.0685
Loa Loa (eye worm) TK/INSR protein kinase 0.0577 0.1769 0.1769
Loa Loa (eye worm) hypothetical protein 0.0372 0.0979 0.0979
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0708 0.2275 0.2275
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0285 0.0646 0.0646
Schistosoma mansoni tyrosine kinase 0.0401 0.109 0.109
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus multilocularis serine:threonine protein kinase N2 0.0251 0.0512 0.0512
Echinococcus multilocularis dual specificity 0.0267 0.0576 0.0576
Loa Loa (eye worm) gastrulation defective protein 1 0.0779 0.2551 0.2551
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0939 0.3168 0.315
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.031 0.0739 0.0739
Leishmania major casein kinase, putative 0.0209 0.035 0.0324
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Plasmodium falciparum thioredoxin reductase 0.0939 0.3168 0.315
Brugia malayi Serine/threonine-protein kinase SULU 0.0428 0.1197 0.1197
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.068 0.2169 0.8274
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus Immunoglobulin 0.0155 0.0142 0.0142
Plasmodium falciparum protein kinase 5 0.0228 0.0426 0.04
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0939 0.3168 0.315
Echinococcus multilocularis down syndrome cell adhesion 0.0131 0.0049 0.0049
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0249 0.0507 0.1549
Echinococcus multilocularis aurora kinase A 0.0225 0.0414 0.0414
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0216 0.0379 0.0379
Brugia malayi SRC-1 0.0293 0.0677 0.0677
Echinococcus granulosus fibropellin Ia 0.0274 0.0602 0.0602
Schistosoma mansoni ephrin receptor 0.0186 0.0264 0.0264
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Brugia malayi Protein kinase domain containing protein 0.0577 0.1769 0.1769
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0379 0.0354
Echinococcus multilocularis serine:threonine protein kinase 3 0.0495 0.1455 0.1455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Trypanosoma cruzi polo-like protein kinase, putative 0.0521 0.1555 0.1533
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0249 0.0507 0.0507
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0516 0.1536 0.1536
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0594 0.1836 0.1836
Schistosoma mansoni serine/threonine protein kinase 0.0316 0.0763 0.0763
Schistosoma mansoni slit 0.0131 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0193 0.0292 0.0292
Schistosoma mansoni tyrosine kinase 0.0577 0.1769 0.1769
Entamoeba histolytica cell division protein kinase 2, putative 0.0228 0.0426 0.214
Echinococcus multilocularis tyrosine protein kinase Srms 0.0239 0.0466 0.0466
Echinococcus multilocularis lachesin 0.0285 0.0646 0.0646
Echinococcus multilocularis cyclin dependent kinase 19 0.0841 0.279 0.279
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Loa Loa (eye worm) CAMK/PIM protein kinase 0.068 0.2169 0.2169
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0239 0.0466 0.0466
Echinococcus multilocularis hemicentin 1 0.0285 0.0646 0.0646
Plasmodium falciparum NIMA related kinase 1 0.0262 0.0555 0.053
Schistosoma mansoni protein kinase 0.0371 0.0977 0.0977
Loa Loa (eye worm) hypothetical protein 0.0355 0.0915 0.0915
Echinococcus multilocularis cyclin dependent kinase 1 0.0228 0.0426 0.0426
Plasmodium vivax calcium-dependent protein kinase, putative 0.0193 0.0292 0.0172
Echinococcus granulosus leucine rich repeat containing protein 4 0.0131 0.0049 0.0049
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0428 0.1197 0.1197
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0116 0.0116
Schistosoma mansoni tyrosine kinase 0.018 0.0241 0.0241
Trichomonas vaginalis CK1 family protein kinase 0.0209 0.035 0.105
Onchocerca volvulus 0.0604 0.1874 0.7144
Echinococcus granulosus insulin receptor 0.0577 0.1769 0.1769
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Cadherin domain containing protein 0.0274 0.0602 0.0602
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0939 0.3168 0.315
Entamoeba histolytica casein kinase, putative 0.0192 0.0286 0.1406
Giardia lamblia Kinase, CMGC DYRK 0.0267 0.0576 0.1491
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.0499 0.2528
Echinococcus multilocularis cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0316 0.0763 0.0763
Brugia malayi Heparan sulfate 0.0155 0.0142 0.0142
Plasmodium vivax unspecified product 0.0192 0.0286 0.0166
Plasmodium vivax protein kinase Crk2 0.0228 0.0426 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0382 0.0382
Brugia malayi Protein kinase domain containing protein 0.0228 0.0426 0.0426
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0159 0.0159 0.0133
Echinococcus multilocularis mitogen activated protein kinase 11 0.0306 0.0726 0.0726
Entamoeba histolytica PH domain containing protein kinase, putative 0.0316 0.0764 0.3923
Trichomonas vaginalis glutathione reductase, putative 0.0939 0.3168 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Brugia malayi protein kinase C3,putative 0.0303 0.0715 0.0715
Brugia malayi Protein kinase domain containing protein 0.0219 0.0391 0.0391
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0247 0.0499 0.0474
Brugia malayi P38 map kinase family protein 2 0.0306 0.0726 0.0726
Schistosoma mansoni serine/threonine protein kinase 0.039 0.1051 0.1051
Echinococcus granulosus neurogenic locus notch protein 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0142 0.0142
Echinococcus multilocularis casein kinase I delta 0.0209 0.035 0.035
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.069 0.2207 0.2207
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0713 0.0713
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Onchocerca volvulus 0.0506 0.1496 0.5694
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0164 0.0138
Giardia lamblia Kinase, NEK 0.0262 0.0555 0.1422
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0274 0.0602 0.2265
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0296 0.0685 0.0661
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0939 0.3168 1
Loa Loa (eye worm) camk/dcamkl protein kinase 0.029 0.0664 0.0664
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0606 0.1884 0.1884
Echinococcus multilocularis Glutaredoxin protein 5 0.0239 0.0468 0.0468
Trichomonas vaginalis AGC family protein kinase 0.0217 0.0382 0.1153
Entamoeba histolytica cell division protein kinase 2, putative 0.0228 0.0426 0.214
Loa Loa (eye worm) TK protein kinase 0.048 0.1397 0.1397
Echinococcus multilocularis cyclin dependent kinase 1 0.0228 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0268 0.058 0.058
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Entamoeba histolytica protein kinase, putative 0.0156 0.0147 0.0674
Trypanosoma cruzi aurora B kinase, putative 0.0225 0.0414 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0163 0.0163
Onchocerca volvulus 0.021 0.0356 0.1323
Brugia malayi Protein kinase domain containing protein 0.0608 0.189 0.189
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0247 0.0499 0.0474
Schistosoma mansoni cell adhesion molecule 0.0155 0.0142 0.0142
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Brugia malayi Serine/threonine-protein kinase Pim-3 0.068 0.2169 0.2169
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0249 0.0507 0.2569
Brugia malayi C1-like domain containing protein 0.0419 0.1162 0.1162
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Loa Loa (eye worm) TK protein kinase 0.0293 0.0676 0.0676
Echinococcus multilocularis Immunoglobulin subtype 0.0155 0.0142 0.0142
Schistosoma mansoni nephrin related 0.0131 0.0049 0.0049
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.016 0.0164 0.0138
Leishmania major protein kinase, putative 0.0225 0.0414 0.0389
Schistosoma mansoni protein kinase 0.0192 0.0286 0.0286
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus multilocularis dual specificity 0.0267 0.0576 0.0576
Giardia lamblia High cysteine protein 0.0274 0.0602 0.1576
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0303 0.0713 0.0713
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0249 0.0507 0.039
Plasmodium vivax tyrosine kinase-like protein, putative 0.0155 0.0144 0.0022
Echinococcus multilocularis C type lectin domian containing protein 0.0506 0.1496 0.1496
Toxoplasma gondii EGF family domain-containing protein 0.0274 0.0602 0.0577
Onchocerca volvulus Neurogenic locus notch homolog 0.0274 0.0602 0.2265
Loa Loa (eye worm) disorganized muscle protein 1 0.0131 0.0049 0.0049
Onchocerca volvulus 0.0126 0.003 0.0073
Echinococcus multilocularis calcium activated potassium channel 0.0259 0.0545 0.0545
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0303 0.0713 0.0713
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0209 0.0602
Echinococcus multilocularis neurogenic locus notch protein 0.0274 0.0602 0.0602
Giardia lamblia Glutamate synthase 0.0249 0.0507 0.1265
Onchocerca volvulus 0.0274 0.0602 0.2265
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0193 0.0292 0.0266
Echinococcus granulosus Immunoglobulin 0.0516 0.1536 0.1536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Onchocerca volvulus 0.0274 0.0602 0.2265
Schistosoma mansoni disulfide oxidoreductase 0.0249 0.0507 0.0507
Schistosoma mansoni netrin receptor unc5 0.0155 0.0142 0.0142
Toxoplasma gondii NADPH-glutathione reductase 0.0939 0.3168 0.315
Brugia malayi Protein kinase domain containing protein 0.0608 0.189 0.189
Entamoeba histolytica protein kinase, putative 0.0137 0.0076 0.0297
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0285 0.0646 0.0646
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0761 0.2479 0.2479
Plasmodium vivax ferrodoxin reductase, putative 0.0249 0.0507 0.039
Trypanosoma cruzi hypothetical protein, conserved 0.0249 0.0507 0.0482
Echinococcus granulosus nervana 2 0.0239 0.0468 0.0468
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Entamoeba histolytica PH domain containing protein kinase, putative 0.0232 0.0439 0.221
Trichomonas vaginalis glutamate synthase, putative 0.0249 0.0507 0.1549
Loa Loa (eye worm) hypothetical protein 0.0276 0.0611 0.0611
Entamoeba histolytica protein kinase , putative 0.0225 0.0414 0.2078
Echinococcus granulosus mitogen activated protein kinase 0.016 0.0164 0.0164
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0939 0.3168 0.3168
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0149 0.0122 0.0096
Brugia malayi Disorganized muscle protein 1 0.0131 0.0049 0.0049
Onchocerca volvulus 0.0209 0.035 0.1299
Echinococcus granulosus protein tyrosine kinase 0.055 0.1665 0.1665
Schistosoma mansoni g1/s-specific cyclin C 0.1221 0.4256 0.4256
Brugia malayi hypothetical protein 0.0155 0.0142 0.0142
Schistosoma mansoni hemicentin 0.0148 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0533 0.1603 0.1603
Trypanosoma brucei protein kinase, putative 0.0247 0.0499 0.0474
Onchocerca volvulus Serine\/threonine kinase homolog 0.0316 0.0763 0.2884
Schistosoma mansoni protein kinase 0.0838 0.2775 0.2775
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0426 0.0426
Brugia malayi Fes/CIP4 homology domain containing protein 0.0197 0.0307 0.0307
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0426 0.129
Onchocerca volvulus 0.0131 0.0049 0.0146
Trichomonas vaginalis AGC family protein kinase 0.0329 0.0815 0.2528
Echinococcus multilocularis tyrosine protein kinase shark 0.0331 0.0823 0.0823
Entamoeba histolytica hypothetical protein 0.0366 0.0956 0.4934
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Echinococcus multilocularis mitogen activated protein kinase 14 0.0306 0.0726 0.0726
Onchocerca volvulus 0.0172 0.0209 0.0759
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.1292 0.1292
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0249 0.0507 0.0507
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Echinococcus granulosus serine threonine protein kinase nrc 0.0301 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus multilocularis raf serine:threonine protein kinase 0.0143 0.0098 0.0098
Brugia malayi Delta serrate ligand family protein 0.0274 0.0602 0.0602
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0939 0.3168 0.2803
Echinococcus granulosus tyrosine kinase 0.0239 0.0466 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0521 0.1555 0.1555
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0356 0.0356
Echinococcus multilocularis serine:threonine protein kinase 0.0219 0.0391 0.0391
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.1337 0.4702 0.4702
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0249 0.0507 0.2569
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0249 0.0507 0.0482
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0939 0.3168 0.315
Loa Loa (eye worm) hypothetical protein 0.0517 0.1538 0.1538
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0225 0.0414 0.0414
Brugia malayi map kinase activated protein kinase protein 2 0.0761 0.2479 0.2479
Leishmania major hypothetical protein, conserved 0.0249 0.0507 0.0482
Entamoeba histolytica protein kinase, putative 0.0125 0.0029 0.0052
Echinococcus granulosus titin 0.0131 0.0049 0.0049
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0644 0.2029 0.2029
Plasmodium falciparum calcium-dependent protein kinase 1 0.0193 0.0292 0.0266
Plasmodium falciparum calcium-dependent protein kinase 3 0.0193 0.0292 0.0266
Brugia malayi serine/threonine protein kinase 6 0.0225 0.0414 0.0414
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0267 0.0575 0.1766
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0285 0.0646 0.0646
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Echinococcus granulosus neurogenic locus notch protein 0.0274 0.0602 0.0602
Schistosoma mansoni protein kinase 0.0838 0.2775 0.2775
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0249 0.0507 0.0482
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0418 0.1156 0.1156
Brugia malayi SH2 domain containing protein 0.0418 0.1156 0.1156
Echinococcus granulosus low density lipoprotein receptor ldl 0.0155 0.0142 0.0142
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0165 0.0181 0.0181
Echinococcus granulosus protein kinase shaggy 0.0247 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0355 0.0915 0.0915
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Onchocerca volvulus 0.0146 0.011 0.0379
Echinococcus granulosus casein kinase I delta 0.0209 0.035 0.035
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0293 0.0677 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0428 0.1197 0.1197
Loa Loa (eye worm) hypothetical protein 0.0148 0.0116 0.0116
Leishmania major NADH dehydrogenase, putative 0.0249 0.0507 0.0482
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0217 0.0382 0.0357
Echinococcus multilocularis insulin receptor 0.0577 0.1769 0.1769
Brugia malayi ephrin receptor 1 precursor 0.0121 0.0011 0.0011
Onchocerca volvulus 0.0131 0.0049 0.0146
Brugia malayi Protein kinase domain containing protein 0.0841 0.279 0.279
Giardia lamblia Kinase, STE STE20 0.0162 0.0171 0.0161
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0131 0.0051 0.0051
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0387 0.1036 0.1036
Loa Loa (eye worm) hypothetical protein 0.0892 0.2986 0.2986
Loa Loa (eye worm) hypothetical protein 0.0268 0.058 0.058
Schistosoma mansoni glutamate synthase 0.0249 0.0507 0.0507
Echinococcus multilocularis casein kinase i 0.0209 0.035 0.035
Schistosoma mansoni tyrosine kinase 0.0348 0.0887 0.0887
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0148 0.0116 0.0116
Entamoeba histolytica protein kinase, putative 0.0165 0.0181 0.0852
Entamoeba histolytica protein kinase, putative 0.0193 0.0292 0.1434
Onchocerca volvulus 0.0131 0.0049 0.0146
Schistosoma mansoni serine/threonine kinase 0.0418 0.1158 0.1158
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0225 0.0414 0.2078
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0316 0.0763 0.0763
Loa Loa (eye worm) hypothetical protein 0.0126 0.003 0.003
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0228 0.0426 0.0426
Schistosoma mansoni cell adhesion molecule 0.0303 0.0713 0.0713
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0939 0.3168 0.3168
Echinococcus granulosus tyrosine protein kinase ABL1 0.0126 0.003 0.003
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0249 0.0507 0.0482
Loa Loa (eye worm) hypothetical protein 0.0349 0.0892 0.0892
Schistosoma mansoni slit 0.0274 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.023 0.0433 0.0433
Brugia malayi MAP kinase sur-1 0.016 0.0164 0.0164
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0939 0.3168 1
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Onchocerca volvulus 0.0124 0.0023 0.0045
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0249 0.0507 0.1549
Trypanosoma cruzi casein kinase II, putative 0.0192 0.0286 0.0261
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0159 0.0159 0.0133
Echinococcus granulosus protein kinase 0.0295 0.0682 0.0682
Echinococcus multilocularis tyrosine protein kinase HCK 0.0176 0.0223 0.0223
Entamoeba histolytica protein kinase domain containing protein 0.0247 0.0499 0.2528
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0221 0.0398 0.0398
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0193 0.0292 0.0292
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0306 0.0726 0.0702
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0156 0.0147 0.0147
Brugia malayi phosphoinositide-dependent protein kinase I 0.0156 0.0147 0.0147
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0387 0.1037 0.1037
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.182 0.6564 0.6564
Echinococcus granulosus insulin growth factor binding 0.0131 0.0049 0.0049
Schistosoma mansoni protein kinase 0.0225 0.0414 0.0414
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0576 0.0576
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.039 0.1051 0.1051
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0293 0.0677 0.0677
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus multilocularis titin 0.021 0.0356 0.0356
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0193 0.0292 0.0266
Brugia malayi Prion-like- 0.0285 0.0646 0.0646
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.018 0.0241 0.0241
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0249 0.0507 0.0507
Echinococcus multilocularis tyrosine protein kinase otk 0.0285 0.0646 0.0646
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0162 0.0171 0.0799
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0939 0.3168 0.315
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0761 0.2479 0.2479
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0172 0.0209 0.0209
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0296 0.0685 0.0661
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0521 0.1555 0.1555
Toxoplasma gondii rhoptry neck protein RON1 0.0506 0.1496 0.1474
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0217 0.0382 0.0357
Brugia malayi Protein kinase domain containing protein 0.027 0.0588 0.0588
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0217 0.0382 0.0357
Brugia malayi Doublecortin family protein 0.029 0.0664 0.0664
Giardia lamblia Kinase, NEK 0.0262 0.0555 0.1422
Trypanosoma cruzi trypanothione reductase, putative 0.0939 0.3168 0.315
Echinococcus granulosus tyrosine protein kinase otk 0.0285 0.0646 0.0646
Echinococcus granulosus casein kinase I gamma 0.0411 0.113 0.113
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0155 0.0143 0.0143
Brugia malayi Protein kinase domain containing protein 0.0118 0.0001 0.0001
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0671 0.2132 0.2132
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Brugia malayi casein kinase 1, delta 0.0209 0.035 0.035
Brugia malayi Sushi domain 0.0506 0.1496 0.1496
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.016 0.0164 0.0138
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0939 0.3168 0.2803
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Schistosoma mansoni cell adhesion molecule 0.0285 0.0646 0.0646
Onchocerca volvulus 0.0126 0.003 0.0073
Echinococcus multilocularis fibropellin Ia 0.0274 0.0602 0.0602
Onchocerca volvulus 0.0148 0.0116 0.0404
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1337 0.4702 0.4702
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0303 0.0713 0.0713
Plasmodium falciparum serine/threonine protein kinase, putative 0.0225 0.0414 0.0389
Echinococcus granulosus titin 0.021 0.0356 0.0356
Trypanosoma brucei aurora B kinase 0.0225 0.0414 0.0389
Schistosoma mansoni myosin-binding protein-related 0.0148 0.0116 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Brugia malayi serine/threonine kinase 12 0.0225 0.0414 0.0414
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0173 0.0214 0.0214
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Brugia malayi hypothetical protein 0.0428 0.1197 0.1197
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0954 0.3226 0.3226
Schistosoma mansoni protein kinase 0.0165 0.0181 0.0181
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Echinococcus granulosus mitogen activated protein kinase 14 0.0306 0.0726 0.0726
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0249 0.0507 0.0507
Echinococcus granulosus neuroglian 0.0647 0.2039 0.2039
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0131 0.0051 0.0051
Onchocerca volvulus 0.0268 0.058 0.2183
Trypanosoma brucei polo-like protein kinase 0.0521 0.1555 0.1533
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0144 0.0101 0.0101
Brugia malayi kettin 0.0131 0.0049 0.0049
Brugia malayi Temporarily assigned gene name protein 59 0.0216 0.0379 0.0379
Onchocerca volvulus 0.0276 0.0611 0.2299
Echinococcus granulosus calcium dependent protein kinase 0.0131 0.0052 0.0052
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0249 0.0507 0.0507
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0426 0.129
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0228 0.0426 0.0426
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0387 0.1036 0.1036
Loa Loa (eye worm) TK protein kinase 0.0176 0.0223 0.0223
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Echinococcus granulosus NDR protein kinase 0.031 0.0739 0.0739
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0249 0.0507 0.0507
Echinococcus multilocularis glutamate synthase 0.0249 0.0507 0.0507
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0418 0.1158 0.1158
Trypanosoma cruzi cdc2-related kinase 1 0.0228 0.0426 0.04
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0371 0.0977 0.0977
Onchocerca volvulus 0.0274 0.0602 0.2265
Onchocerca volvulus 0.0627 0.1964 0.749
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0249 0.0507 0.0507
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0329 0.0815 0.0815
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Entamoeba histolytica protein kinase domain containing protein 0.0125 0.0026 0.0037
Schistosoma mansoni hypothetical protein 0.0148 0.0116 0.0116
Brugia malayi Muscle positioning protein 4 0.0274 0.0602 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0219 0.0391 0.1179
Echinococcus multilocularis titin 0.0131 0.0049 0.0049
Schistosoma mansoni cell polarity protein 0.0274 0.0602 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0249 0.0507 0.0482
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0164 0.0164
Brugia malayi putative serine/threonine kinase SADA gamma 0.0149 0.0122 0.0122
Echinococcus granulosus serine:threonine protein kinase 0.0219 0.0391 0.0391
Trichomonas vaginalis STE family protein kinase 0.0262 0.0555 0.1701
Echinococcus multilocularis protein jagged 2 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Entamoeba histolytica hypothetical protein 0.0235 0.0451 0.2275
Trichomonas vaginalis CK1 family protein kinase 0.0209 0.035 0.105
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0149 0.0122 0.0096
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Schistosoma mansoni cell adhesion molecule 0.0131 0.0049 0.0049
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0249 0.0507 0.2569
Schistosoma mansoni serine/threonine protein kinase 0.0416 0.115 0.115
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0506 0.1496 0.1496
Echinococcus granulosus protein jagged 1 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0144 0.0144
Onchocerca volvulus 0.0506 0.1496 0.5694
Leishmania major protein kinase A catalytic subunit isoform 2 0.0217 0.0382 0.0357
Echinococcus multilocularis roundabout 2 0.0303 0.0713 0.0713
Schistosoma mansoni protein kinase 0.0209 0.035 0.035
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0209 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0382 0.0382
Onchocerca volvulus 0.0131 0.0051 0.0153
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Toxoplasma gondii AGC kinase 0.0217 0.0382 0.0357
Loa Loa (eye worm) AGC/PKG protein kinase 0.016 0.0163 0.0163
Brugia malayi Protein kinase domain containing protein 0.182 0.6564 0.6564
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0144 0.0101 0.0101
Plasmodium falciparum serine/threonine protein kinase 0.0159 0.0159 0.0133
Schistosoma mansoni nephrin 0.0664 0.2107 0.2107
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0249 0.0507 0.0507
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.039 0.1051 0.1051
Echinococcus granulosus protein kinase C gamma type 0.0389 0.1045 0.1045
Onchocerca volvulus 0.0506 0.1496 0.5694
Onchocerca volvulus 0.0131 0.0049 0.0146
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0249 0.0507 0.0482
Schistosoma mansoni septate junction protein 0.0285 0.0646 0.0646
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0155 0.0142 0.0142
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0685 0.0685
Giardia lamblia Kinase, CMGC CDK 0.0228 0.0426 0.0997
Echinococcus granulosus neurogenic locus notch protein 4 0.0274 0.0602 0.0602
Onchocerca volvulus 0.0247 0.0499 0.1871
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.035 0.0893 0.0893
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Plasmodium falciparum calcium-dependent protein kinase 5 0.0193 0.0292 0.0266
Schistosoma mansoni tyrosine kinase 0.0401 0.109 0.109
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0235 0.0451 0.0451
Entamoeba histolytica serine/threonine protein kinase, putative 0.0521 0.1555 0.809
Entamoeba histolytica protein kinase, putative 0.0563 0.1718 0.8948
Loa Loa (eye worm) hypothetical protein 0.0148 0.0116 0.0116
Loa Loa (eye worm) protein kinase domain-containing protein 0.0411 0.113 0.113
Leishmania major hypothetical protein, conserved 0.0249 0.0507 0.0482
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0495 0.1455 0.1455
Schistosoma mansoni serine/threonine protein kinase 0.047 0.1356 0.1356
Onchocerca volvulus 0.0126 0.003 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.0398 0.1202
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Echinococcus multilocularis neurogenic locus notch protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0447 0.127 0.127
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0239 0.0468 0.0468
Brugia malayi Protein kinase domain containing protein 0.068 0.2169 0.2169
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0209 0.035 0.0324
Plasmodium falciparum glutathione reductase 0.2711 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0178 0.0233 0.0233
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Echinococcus granulosus hemicentin 1 0.0285 0.0646 0.0646
Schistosoma mansoni roundabout 0.0285 0.0646 0.0646
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0131 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0627 0.1964 0.1964
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Echinococcus granulosus titin 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Echinococcus granulosus mitogen activated protein kinase 3 0.016 0.0164 0.0164
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0249 0.0507 0.0507
Echinococcus granulosus protein jagged 2 0.0274 0.0602 0.0602
Plasmodium vivax serine/threonine protein kinase, putative 0.0159 0.0159 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.016 0.0164 0.0138
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0172 0.0209 0.0209
Echinococcus multilocularis casein kinase I delta 0.0209 0.035 0.035
Echinococcus multilocularis casein kinase I alpha 0.0209 0.035 0.035
Echinococcus granulosus Glutaredoxin protein 5 0.0239 0.0468 0.0468
Echinococcus granulosus casein kinase I delta 0.0209 0.035 0.035
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Giardia lamblia Kinase, CDC7 0.0172 0.0209 0.0286
Giardia lamblia Kinase, CK1 Casein kinase 0.0209 0.035 0.0749
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0159 0.0159 0.0133
Echinococcus multilocularis neuroglian 0.0647 0.2039 0.2039
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Giardia lamblia Kinase, CMGC CDK 0.0228 0.0426 0.0997
Brugia malayi Immunoglobulin I-set domain containing protein 0.0155 0.0142 0.0142
Entamoeba histolytica cyclin C, putative 0.0615 0.1918 1
Onchocerca volvulus 0.0506 0.1496 0.5694
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0147 0.0147
Echinococcus granulosus contactin 0.0303 0.0713 0.0713
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0509 0.151 0.151
Brugia malayi Protein kinase domain containing protein 0.0329 0.0815 0.0815
Schistosoma mansoni nephrin related 0.0155 0.0142 0.0142
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0193 0.029 0.029
Schistosoma mansoni cell adhesion molecule 0.0148 0.0116 0.0116
Loa Loa (eye worm) SRC-1 0.0293 0.0677 0.0677
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0293 0.0677 0.0677
Giardia lamblia Kinase, CMGC CLK 0.0296 0.0685 0.185
Brugia malayi Protein kinase domain containing protein 0.0373 0.0984 0.0984
Loa Loa (eye worm) hypothetical protein 0.0216 0.0379 0.0379
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.113 0.113
Echinococcus granulosus raf serine:threonine protein kinase 0.0143 0.0098 0.0098
Schistosoma mansoni protein kinase 0.0123 0.0019 0.0019
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0249 0.0507 0.0482
Brugia malayi Variant SH3 domain containing protein 0.0144 0.0101 0.0101
Schistosoma mansoni serine/threonine kinase 0.031 0.0739 0.0739
Echinococcus granulosus casein kinase I alpha 0.0209 0.035 0.035
Loa Loa (eye worm) TK/FAK protein kinase 0.0555 0.1687 0.1687
Schistosoma mansoni serine/threonine protein kinase 0.047 0.1356 0.1356
Plasmodium falciparum serine/threonine protein kinase KIN 0.0149 0.0122 0.0096
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0301 0.0708 0.0683
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.021 0.0356 0.0356
Trichomonas vaginalis CAMK family protein kinase 0.0243 0.0482 0.147
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0242 0.0479 0.0479
Loa Loa (eye worm) AGC/NDR protein kinase 0.031 0.0739 0.0739
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0155 0.0142 0.0142
Echinococcus multilocularis c4b binding protein beta chain 0.0506 0.1496 0.1496
Echinococcus multilocularis insulin growth factor binding 0.0131 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Schistosoma mansoni protein kinase 0.0708 0.2275 0.2275
Giardia lamblia Thioredoxin reductase 0.0249 0.0507 0.1265
Loa Loa (eye worm) casein kinase 0.0349 0.089 0.089
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Schistosoma mansoni serine/threonine protein kinase 0.056 0.1706 0.1706
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2711 1 1
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0296 0.0685 0.0661
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0249 0.0507 0.1549
Schistosoma mansoni protein kinase 0.0295 0.0682 0.0682
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1402 0.4951 0.4951
Treponema pallidum NADH oxidase 0.0939 0.3168 1
Echinococcus multilocularis neurogenic locus notch protein 4 0.0274 0.0602 0.0602
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Schistosoma mansoni tyrosine kinase 0.055 0.1665 0.1665
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0274 0.0602 0.0602
Brugia malayi glutamate synthase 0.0249 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0149 0.0122 0.0122
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0116 0.0116
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Onchocerca volvulus 0.0131 0.0049 0.0146
Echinococcus multilocularis netrin receptor unc 5 0.0211 0.0358 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0939 0.3168 0.3168
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0247 0.0499 0.0474
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Echinococcus multilocularis 0.0131 0.0049 0.0049
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0155 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0801 0.2636 0.2636
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0249 0.0507 0.0482
Echinococcus multilocularis Protein kinase C, brain isozyme 0.047 0.1356 0.1356
Leishmania major protein kinase A catalytic subunit 0.0217 0.0382 0.0357
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) Notch2 0.0274 0.0602 0.0602
Schistosoma mansoni atypical protein kinase C 0.0563 0.1715 0.1715
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0296 0.0685 0.0661
Schistosoma mansoni septate junction protein 0.0285 0.0646 0.0646
Echinococcus granulosus hypothetical protein 0.0233 0.0445 0.0445
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0193 0.0292 0.0172
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0159 0.0159 0.0159
Schistosoma mansoni nephrin 0.0303 0.0713 0.0713
Trypanosoma cruzi Protein kinase B 0.0316 0.0764 0.074
Schistosoma mansoni titin 0.0148 0.0116 0.0116
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0448 0.1275 0.1275
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.0602 0.0602
Entamoeba histolytica protein kinase, putative 0.0267 0.0576 0.2932
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0545 0.0545
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0419 0.1162 0.1162
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.035 0.035
Loa Loa (eye worm) AGC/PKN protein kinase 0.056 0.1706 0.1706
Echinococcus multilocularis cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Brugia malayi Protein kinase domain 0.0165 0.0181 0.0181
Brugia malayi cell division control protein 2 homolog 0.0228 0.0426 0.0426
Loa Loa (eye worm) AGC/PKA protein kinase 0.0217 0.0382 0.0382
Echinococcus granulosus protein jagged 2 0.0274 0.0602 0.0602
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.016 0.0164 0.0138
Echinococcus multilocularis cyclin dependent kinase 0.0228 0.0426 0.0426
Echinococcus granulosus tyrosine protein kinase Src42A 0.0293 0.0677 0.0677
Echinococcus granulosus serine:threonine protein kinase 3 0.0495 0.1455 0.1455
Loa Loa (eye worm) hypothetical protein 0.0173 0.0211 0.0211
Giardia lamblia Kinase, AGC AKT 0.0225 0.0413 0.0955
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.031 0.0739 0.0739
Toxoplasma gondii AGC kinase 0.0549 0.1662 0.164
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0172 0.0209 0.0209
Brugia malayi Casein kinase II, alpha chain 0.0192 0.0286 0.0286
Echinococcus multilocularis dual specificity protein kinase clk2 0.0296 0.0685 0.0685
Echinococcus granulosus tyrosine protein kinase shark 0.0331 0.0823 0.0823
Schistosoma mansoni vesicular amine transporter 0.0516 0.1536 0.1536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0211 0.0358 0.0358
Brugia malayi Stress-activated protein kinase jnk-1 0.0509 0.151 0.151
Brugia malayi hypothetical protein 0.0533 0.1603 0.1603
Echinococcus granulosus cyclin dependent kinase 19 0.0841 0.279 0.279
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Leishmania major trypanothione reductase 0.2711 1 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0126 0.003 0.003
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Echinococcus multilocularis protein kinase c iota type 0.0551 0.167 0.167
Brugia malayi Protein kinase c protein 2 0.0222 0.0402 0.0402
Trypanosoma cruzi hypothetical protein, conserved 0.0249 0.0507 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0545 0.0545
Onchocerca volvulus 0.0506 0.1496 0.5694
Loa Loa (eye worm) hypothetical protein 0.0249 0.0507 0.0507
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0249 0.0507 0.0482
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0193 0.0292 0.0292
Brugia malayi notch-like transmembrane receptor 0.0274 0.0602 0.0602
Brugia malayi STE20-like kinase MST 0.0495 0.1455 0.1455
Echinococcus multilocularis neurogenic locus protein delta 0.0274 0.0602 0.0602
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Echinococcus granulosus tyrosine protein kinase Lyn 0.0356 0.0917 0.0917
Schistosoma mansoni tyrosine kinase 0.035 0.0893 0.0893
Echinococcus granulosus serine/threonine protein kinase 0.0316 0.0764 0.0764
Echinococcus granulosus tyrosine kinase 0.0126 0.003 0.003
Schistosoma mansoni protein kinase 0.0125 0.0026 0.0026
Echinococcus granulosus peroxidasin 0.0286 0.0648 0.0648
Trypanosoma cruzi cdc2-related kinase 1 0.0228 0.0426 0.04
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0193 0.0292 0.0266
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0301 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0379 0.0354
Echinococcus multilocularis casein kinase ii subunit alpha 0.0192 0.0286 0.0286
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0156 0.0147 0.0147
Echinococcus multilocularis protein kinase shaggy 0.0247 0.0499 0.0499
Echinococcus multilocularis peroxidasin 0.0286 0.0648 0.0648
Giardia lamblia Kinase, CMGC SRPK 0.0159 0.0159 0.0123
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0249 0.0507 0.0482
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0708 0.2275 0.2275
Echinococcus granulosus tyrosine protein kinase HCK 0.0176 0.0223 0.0223
Echinococcus granulosus cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Loa Loa (eye worm) glutathione reductase 0.2711 1 1
Trypanosoma brucei casein kinase I, isoform 2 0.0209 0.035 0.0324
Brugia malayi Protein kinase domain containing protein 0.0708 0.2275 0.2275
Echinococcus multilocularis myosin iiia 0.0162 0.0171 0.0171
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.1441 0.1441
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Schistosoma mansoni tyrosine kinase 0.0293 0.0677 0.0677
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0393 0.1061 0.1061
Echinococcus multilocularis NCK adaptor protein 0.012 0.0007 0.0007
Echinococcus multilocularis mitogen activated protein kinase 14 0.0306 0.0726 0.0726
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.016 0.0164 0.0138
Schistosoma mansoni protein kinase 0.0425 0.1186 0.1186
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0193 0.0292 0.0292
Onchocerca volvulus 0.0131 0.0049 0.0146
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0939 0.3168 0.315
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0419 0.1162 0.1162
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.0398 0.1202
Echinococcus granulosus tyrosine protein kinase Src64B 0.0293 0.0677 0.0677
Trypanosoma brucei rac serine-threonine kinase, putative 0.0563 0.1718 0.1696
Echinococcus multilocularis thioredoxin glutathione reductase 0.2711 1 1
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Onchocerca volvulus Peroxidasin homolog 0.0131 0.0051 0.0153
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Toxoplasma gondii thioredoxin reductase 0.2711 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0192 0.0286 0.1406
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0149 0.0122 0.0096
Entamoeba histolytica casein kinase, putative 0.0209 0.035 0.1741
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Echinococcus multilocularis dual specificity 0.0235 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Entamoeba histolytica protein kinase domain containing protein 0.0225 0.0414 0.2078
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0147 0.0406
Echinococcus granulosus expressed protein 0.0159 0.0159 0.0159
Entamoeba histolytica protein kinase, putative 0.0235 0.0451 0.2275
Loa Loa (eye worm) hypothetical protein 0.0448 0.1275 0.1275
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0239 0.0468 0.0468
Brugia malayi Immunoglobulin I-set domain containing protein 0.048 0.1397 0.1397
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0606 0.1884 0.1884
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus neuroglian 0.0303 0.0713 0.0713
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0217 0.0382 0.0357
Trichomonas vaginalis AGC family protein kinase 0.0329 0.0815 0.2528
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0293 0.0677 0.0677
Brugia malayi Protein kinase domain containing protein 0.0172 0.0209 0.0209
Schistosoma mansoni laminin gamma-3 chain 0.0274 0.0602 0.0602
Echinococcus multilocularis serine threonine protein kinase 0.0389 0.1045 0.1045
Schistosoma mansoni netrin receptor unc5 0.0211 0.0358 0.0358
Brugia malayi basement membrane proteoglycan 0.0155 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi Protein kinase domain containing protein 0.0316 0.0763 0.0763
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0293 0.0677 0.0677
Echinococcus multilocularis roundabout 2 0.0303 0.0713 0.0713
Schistosoma mansoni tyrosine kinase 0.0293 0.0677 0.0677
Onchocerca volvulus Netrin receptor homolog 0.0187 0.0265 0.0973
Echinococcus multilocularis calcium dependent protein kinase 0.0131 0.0052 0.0052
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0509 0.151 0.151
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.2711 1 1
Loa Loa (eye worm) one IG domain family member 0.0131 0.0049 0.0049
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0228 0.0426 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0453 0.1292 0.1292
Echinococcus granulosus nephrin 0.0148 0.0116 0.0116
Echinococcus granulosus serine:threonine protein kinase N2 0.056 0.1706 0.1706
Trypanosoma cruzi NADH dehydrogenase, putative 0.0249 0.0507 0.0482
Schistosoma mansoni protein kinase 0.0165 0.0181 0.0181
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0249 0.0507 0.0507
Leishmania major protein kinase A catalytic subunit isoform 1 0.0217 0.0382 0.0357
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0247 0.0499 0.0499
Echinococcus multilocularis dual specificity 0.0267 0.0576 0.0576
Onchocerca volvulus 0.0148 0.0116 0.0404
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Giardia lamblia Aurora kinase 0.0225 0.0414 0.0959
Onchocerca volvulus 0.0172 0.0209 0.0759
Trichomonas vaginalis STE family protein kinase 0.0162 0.0171 0.0481
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0193 0.0292 0.0172
Echinococcus granulosus Immunoglobulin subtype 0.0155 0.0142 0.0142
Echinococcus multilocularis cyclin 0.0606 0.1884 0.1884
Brugia malayi Protein kinase domain containing protein 0.031 0.0739 0.0739
Echinococcus multilocularis neuroglian 0.0303 0.0713 0.0713
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0221 0.0398 0.0398
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Schistosoma mansoni basigin related 0.0155 0.0142 0.0142
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.0602 0.0602
Schistosoma mansoni peroxidasin 0.0155 0.0144 0.0144
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0285 0.0646 0.0646
Schistosoma mansoni neuroglian 0.0303 0.0713 0.0713
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0425 0.1186 0.1186
Echinococcus granulosus Vam6:Vps39 protein 0.0216 0.0379 0.0379
Loa Loa (eye worm) AUR protein kinase 0.0225 0.0414 0.0414
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0653 0.2063 0.2063
Echinococcus granulosus Protein kinase C brain isozyme 0.047 0.1356 0.1356
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Schistosoma mansoni tyrosine kinase 0.0331 0.0823 0.0823
Echinococcus multilocularis tyrosine protein kinase Abl 0.018 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0279 0.062 0.062
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Leishmania major casein kinase II, putative 0.0192 0.0286 0.0261
Schistosoma mansoni serine/threonine protein kinase 0.0393 0.1061 0.1061
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0148 0.0116 0.0116
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0303 0.0713 0.0713
Brugia malayi Peroxidasin 0.0286 0.0648 0.0648
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Schistosoma mansoni protein kinase 0.0511 0.1515 0.1515
Trichomonas vaginalis AGC family protein kinase 0.031 0.0739 0.2287
Echinococcus granulosus lachesin 0.0285 0.0646 0.0646
Onchocerca volvulus 0.0216 0.0379 0.141
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0316 0.0764 0.074
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0156 0.0147 0.0147
Schistosoma mansoni protein kinase 0.0838 0.2775 0.2775
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Echinococcus multilocularis protein jagged 1 0.0274 0.0602 0.0602
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0242 0.0479 0.0479
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0193 0.0292 0.0292
Schistosoma mansoni septate junction protein 0.0274 0.0602 0.0602
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0155 0.0142 0.0142
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0939 0.3168 1
Trypanosoma cruzi NADH dehydrogenase, putative 0.0249 0.0507 0.0482
Loa Loa (eye worm) animal heme peroxidase 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0578 0.1774 0.1774
Trichomonas vaginalis mercuric reductase, putative 0.0939 0.3168 1
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0242 0.0479 0.0479
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0225 0.0413 0.0413
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0155 0.0142 0.0142
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0144 0.0101 0.0101
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0292 0.0292
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0278 0.0619 0.0619
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0365 0.0953 0.0953
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Echinococcus multilocularis PAK box P21 Rho binding 0.0123 0.0019 0.0019
Loa Loa (eye worm) TK/EPH protein kinase 0.022 0.0395 0.0395
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0316 0.0763 0.0763
Echinococcus granulosus tyrosine protein kinase 0.0293 0.0676 0.0676
Echinococcus granulosus down syndrome cell adhesion 0.0131 0.0049 0.0049
Echinococcus multilocularis epidermal growth factor receptor 0.0463 0.1331 0.1331
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0249 0.0507 0.039
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0249 0.0507 0.0482
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.031 0.0739 0.0739
Echinococcus granulosus dual specificity 0.0267 0.0576 0.0576
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0262 0.0555 0.053
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0296 0.0685 0.0661
Onchocerca volvulus 0.0249 0.0507 0.1902
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0285 0.0646 0.2435
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0267 0.0576 0.0551
Echinococcus multilocularis hemicentin 1 0.0285 0.0646 0.0646
Plasmodium vivax thioredoxin reductase, putative 0.2711 1 1
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0165 0.0181 0.0181
Entamoeba histolytica casein kinase 1, putative 0.0209 0.035 0.1741
Brugia malayi protein kinase C II. 0.0393 0.1061 0.1061
Loa Loa (eye worm) hypothetical protein 0.0197 0.0305 0.0305
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Loa Loa (eye worm) CAMK/PIM protein kinase 0.068 0.2169 0.2169
Trypanosoma cruzi cdc2-related kinase 3 0.0228 0.0426 0.04
Echinococcus multilocularis Immunoglobulin 0.0155 0.0142 0.0142
Trypanosoma brucei hypothetical protein, conserved 0.0249 0.0507 0.0482
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0142 0.0142
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0155 0.0142 0.0142
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0247 0.0499 0.0499
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0165 0.0181 0.0181
Schistosoma mansoni tyrosine kinase 0.0268 0.0579 0.0579
Echinococcus granulosus fibroblast growth factor receptor 4 0.035 0.0893 0.0893
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0418 0.1156 0.1156
Brugia malayi EGF-like domain containing protein 0.0317 0.0767 0.0767
Mycobacterium tuberculosis Probable oxidoreductase 0.0939 0.3168 0.2803
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0479 0.0479
Echinococcus granulosus slit 2 protein 0.0317 0.0767 0.0767
Echinococcus granulosus titin 0.021 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0231 0.0435 0.0435
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0249 0.0507 0.0482
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0838 0.2775 0.2775
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0267 0.0576 0.0551
Brugia malayi GCC2 and GCC3 family protein 0.078 0.2552 0.2552
Brugia malayi SH2 domain containing protein 0.0126 0.003 0.003
Loa Loa (eye worm) TK protein kinase 0.0354 0.0912 0.0912
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0126 0.003 0.0058
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0303 0.0713 0.0713
Entamoeba histolytica protein kinase, putative 0.0235 0.0451 0.2275
Onchocerca volvulus 0.0126 0.003 0.0073
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Onchocerca volvulus 0.0274 0.0602 0.2265
Giardia lamblia NADH oxidase lateral transfer candidate 0.0939 0.3168 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0193 0.0292 0.0172
Onchocerca volvulus 0.0372 0.0979 0.3711
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0249 0.0507 0.1549
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0939 0.3168 0.3084
Entamoeba histolytica protein kinase domain containing protein 0.039 0.1051 0.5433
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Schistosoma mansoni vam6/vps39 related 0.0216 0.0379 0.0379
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0594 0.1836 0.1836
Entamoeba histolytica protein kinase, putative 0.0549 0.1662 0.8651
Schistosoma mansoni tyrosine kinase 0.0463 0.1331 0.1331
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0126 0.003 0.003
Echinococcus granulosus glutamate synthase 0.0249 0.0507 0.0507
Echinococcus multilocularis rac serine:threonine kinase 0.0316 0.0764 0.0764
Entamoeba histolytica p21-activated kinase 0.0179 0.0237 0.1149
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0131 0.0049 0.0049
Schistosoma mansoni basigin related 0.0155 0.0142 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0131 0.0049 0.0049
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0249 0.0507 0.0482
Echinococcus granulosus casein kinase ii subunit alpha 0.0192 0.0286 0.0286
Echinococcus granulosus N chimaerin 0.0144 0.0101 0.0101
Echinococcus granulosus dual specificity 0.0235 0.0451 0.0451
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0279 0.062 0.062
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Schistosoma mansoni cell adhesion molecule 0.0303 0.0713 0.0713
Onchocerca volvulus Tyrosine kinase homolog 0.0797 0.2619 1
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0472 0.1367 0.1367
Echinococcus granulosus notch 0.0274 0.0602 0.0602
Plasmodium vivax glycogen synthase kinase 3, putative 0.0247 0.0499 0.0382
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Brugia malayi pregnancy-associated plasma protein-A 0.0506 0.1496 0.1496
Trypanosoma brucei cdc2-related kinase 1 0.0228 0.0426 0.04
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0131 0.0049 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0306 0.0726 0.0702
Echinococcus multilocularis serine:threonine protein kinase 38 0.031 0.0739 0.0739
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0338 0.0851 0.0851
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus multilocularis death associated protein kinase 1 0.0847 0.2811 0.2811
Echinococcus multilocularis ephrin type A receptor 4 A 0.0186 0.0264 0.0264
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0225 0.0414 0.2078
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Toxoplasma gondii CMGC kinase, CK2 family 0.0192 0.0286 0.0261
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0101 0.0101
Brugia malayi Fibronectin type III domain containing protein 0.0533 0.1603 0.1603
Onchocerca volvulus 0.0506 0.1496 0.5694
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0155 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0801 0.2636 0.2636
Onchocerca volvulus 0.0131 0.0049 0.0146
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0141 0.009 0.009
Echinococcus granulosus neural cadherin 0.0274 0.0602 0.0602
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Plasmodium falciparum glutathione reductase 0.0939 0.3168 0.315
Brugia malayi Prion-like- 0.0131 0.0049 0.0049
Schistosoma mansoni serine/threonine-protein kinase 0.0316 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0533 0.1603 0.1603
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0209 0.035 0.035
Echinococcus granulosus roundabout 2 0.0819 0.2703 0.2703
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0149 0.0122 0.0122
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.035 0.0893 0.0893
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Trypanosoma cruzi cdc2-related kinase 3 0.0228 0.0426 0.04
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Echinococcus granulosus twitchin 0.0709 0.2279 0.2279
Trypanosoma brucei cdc2-related kinase 3 0.0228 0.0426 0.04
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Echinococcus granulosus delta-like protein 1 0.0274 0.0602 0.0602
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0939 0.3168 0.2803
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0225 0.0414 0.2078
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.016 0.0164 0.0138
Loa Loa (eye worm) hypothetical protein 0.0303 0.0713 0.0713
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi Cadherin domain containing protein 0.0274 0.0602 0.0602
Echinococcus granulosus cyclin 0.0606 0.1884 0.1884
Echinococcus multilocularis fibroblast growth factor receptor 4 0.035 0.0893 0.0893
Schistosoma mansoni glutamate synthase 0.0249 0.0507 0.0507
Brugia malayi Cyclin, N-terminal domain containing protein 0.0606 0.1884 0.1884
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0217 0.0382 0.0264
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0671 0.2132 0.2132
Loa Loa (eye worm) AGC/PKA protein kinase 0.0217 0.0382 0.0382
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0521 0.1555 0.1555
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0293 0.0677 0.0677
Echinococcus granulosus tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0939 0.3168 0.315
Echinococcus multilocularis titin 0.0131 0.0049 0.0049
Schistosoma mansoni tyrosine kinase 0.0463 0.1331 0.1331
Schistosoma mansoni serine/threonine protein kinase 0.016 0.0163 0.0163
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.003 0.003
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0228 0.0426 0.04
Leishmania major protein kinase, putative 0.0296 0.0685 0.0661
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0217 0.0382 0.0357
Echinococcus multilocularis notch 0.0274 0.0602 0.0602
Entamoeba histolytica protein kinase, putative 0.0225 0.0414 0.2078
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Trichomonas vaginalis CK1 family protein kinase 0.0209 0.035 0.105
Loa Loa (eye worm) TK/EGFR protein kinase 0.0663 0.2104 0.2104
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.1367 0.1367
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0379 0.0379
Schistosoma mansoni serine/threonine-protein kinase 0.0316 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0173 0.0211 0.0211
Onchocerca volvulus 0.0126 0.003 0.0073
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Trichomonas vaginalis glutamate synthase, putative 0.0249 0.0507 0.1549
Giardia lamblia Kinase, PLK 0.0521 0.1555 0.4705
Echinococcus multilocularis expressed conserved protein 0.016 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Giardia lamblia Kinase, STE STE20 0.0165 0.0181 0.0195
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0939 0.3168 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Schistosoma mansoni kinase 0.0557 0.1693 0.1693
Onchocerca volvulus 0.0506 0.1496 0.5694
Brugia malayi Egg laying defective protein 4 0.016 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0521 0.1555 0.1533
Loa Loa (eye worm) hypothetical protein 0.0124 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0939 0.3168 1
Echinococcus granulosus basement membrane specific heparan sulfate 0.0155 0.0142 0.0142
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0939 0.3168 0.3084
Onchocerca volvulus 0.0274 0.0602 0.2265
Echinococcus multilocularis activin receptor type 0.0125 0.0026 0.0026
Brugia malayi Kinase associated domain 1 family protein 0.0197 0.0305 0.0305
Schistosoma mansoni tyrosine kinase 0.018 0.0241 0.0241
Plasmodium falciparum calcium-dependent protein kinase 4 0.0193 0.0292 0.0266
Echinococcus multilocularis roundabout 2 0.0819 0.2703 0.2703
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Echinococcus multilocularis Immunoglobulin 0.0516 0.1536 0.1536
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0217 0.0382 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.068 0.2169 0.2169
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0708 0.2275 0.2275
Onchocerca volvulus 0.0126 0.003 0.0073
Brugia malayi Protein kinase domain containing protein 0.029 0.0664 0.0664
Schistosoma mansoni serine/threonine protein kinase 0.0841 0.279 0.279
Echinococcus multilocularis tyrosine kinase 0.0126 0.003 0.003
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0155 0.0142 0.0142
Echinococcus multilocularis N chimaerin 0.0144 0.0101 0.0101
Trichomonas vaginalis CAMK family protein kinase 0.0243 0.0482 0.147
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0098 0.0098
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Plasmodium falciparum calcium-dependent protein kinase 2 0.0193 0.0292 0.0266
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0228 0.0426 0.0426
Plasmodium vivax serine/threonine kinase-1, putative 0.0296 0.0685 0.0571
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0172 0.0209 0.0209
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.068 0.2169 0.2169
Echinococcus granulosus nervana 2 0.0239 0.0468 0.0468
Loa Loa (eye worm) hypothetical protein 0.0158 0.0153 0.0153
Brugia malayi Temporarily assigned gene name protein 59 0.0249 0.0507 0.0507
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi probable protein kinase 0.0511 0.1515 0.1515
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0192 0.0286 0.0166
Echinococcus granulosus dual specificity 0.0267 0.0576 0.0576
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0239 0.0469 0.0444
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0155 0.0142 0.0142
Entamoeba histolytica protein kinase, putative 0.0563 0.1718 0.8948
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Cam kinase protein 1 0.0193 0.0292 0.0292
Leishmania major protein kinase, putative 0.0296 0.0685 0.0661
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0296 0.0685 0.0661
Entamoeba histolytica protein kinase, putative 0.0247 0.0499 0.2528
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi Protein kinase domain containing protein 0.0371 0.0977 0.0977
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Echinococcus multilocularis twitchin 0.0193 0.0289 0.0289
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Brugia malayi Calcium binding EGF domain containing protein 0.0274 0.0602 0.0602
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0147 0.0406
Brugia malayi Protein kinase domain containing protein 0.0411 0.113 0.113
Toxoplasma gondii selenide, water dikinase 0.0249 0.0507 0.0482
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0315 0.0761 0.0761
Brugia malayi protein-tyrosine kinase 0.0239 0.0466 0.0466
Trypanosoma cruzi casein kinase, putative 0.0209 0.035 0.0324
Entamoeba histolytica PH domain containing protein kinase, putative 0.0232 0.0439 0.221
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0472 0.1367 0.1367
Echinococcus granulosus casein kinase I alpha 0.0209 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.0516 0.1536 0.1536
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0866 0.2885 0.2885
Trichomonas vaginalis CMGC family protein kinase 0.0296 0.0685 0.2115
Echinococcus granulosus casein kinase i 0.0209 0.035 0.035
Brugia malayi intracellular kinase 0.0247 0.0499 0.0499
Echinococcus granulosus roundabout 2 0.0303 0.0713 0.0713
Loa Loa (eye worm) hypothetical protein 0.0563 0.1715 0.1715
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0274 0.0602 0.0602
Echinococcus multilocularis Immunoglobulin 0.0155 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi serine/threonine-protein kinase 6 0.0225 0.0414 0.0414
Echinococcus multilocularis casein kinase I gamma 0.0411 0.113 0.113
Trichomonas vaginalis CAMK family protein kinase 0.0418 0.1158 0.3615
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Plasmodium falciparum thioredoxin reductase 0.2711 1 1
Trichomonas vaginalis AGC family protein kinase 0.0344 0.0872 0.2707
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0379 0.0379
Brugia malayi Prion-like- 0.0131 0.0049 0.0049
Echinococcus multilocularis slit 2 protein 0.0317 0.0767 0.0767
Echinococcus granulosus tyrosine protein kinase Blk 0.0239 0.0466 0.0466
Schistosoma mansoni protein kinase 0.0425 0.1186 0.1186
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Onchocerca volvulus Putative cubilin 0.0274 0.0602 0.2265
Schistosoma mansoni titin 0.021 0.0356 0.0356
Loa Loa (eye worm) hypothetical protein 0.0166 0.0186 0.0186
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0608 0.189 0.189
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0306 0.0726 0.0726
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Brugia malayi Protein kinase domain containing protein 0.0866 0.2885 0.2885
Echinococcus multilocularis 0.0233 0.0445 0.0445
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi Prion-like- 0.0131 0.0049 0.0049
Entamoeba histolytica thioredoxin reductase, putative 0.0249 0.0507 0.2569
Giardia lamblia Kinase, CMGC MAPK 0.016 0.0164 0.0139
Trichomonas vaginalis CMGC family protein kinase 0.0228 0.0426 0.129
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0217 0.0382 0.0357
Giardia lamblia Kinase, CMGC GSK 0.0247 0.0499 0.1239
Echinococcus granulosus rho-associated protein kinase 1 0.0627 0.1964 0.1964
Schistosoma mansoni hypothetical protein 0.0216 0.0379 0.0379
Schistosoma mansoni hypothetical protein 0.0197 0.0305 0.0305
Echinococcus multilocularis mitogen activated protein kinase 0.016 0.0164 0.0164
Giardia lamblia Kinase, NEK 0.0262 0.0555 0.1422
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0156 0.0147 0.0147
Trypanosoma brucei SNF1-related protein kinases, putative 0.0149 0.0122 0.0096
Echinococcus multilocularis c src tyrosine kinase 0.018 0.0241 0.0241
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Onchocerca volvulus 0.0506 0.1496 0.5694
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0267 0.0576 0.0551
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0293 0.0677 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0426 0.0426
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0296 0.0685 0.0661
Echinococcus granulosus cGMP dependent protein kinase 0.016 0.0163 0.0163
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0301 0.0708 0.0683
Schistosoma mansoni growth factor receptor-bound protein 0.012 0.0007 0.0007
Echinococcus granulosus defective proboscis extension response 0.0516 0.1536 0.1536
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0162 0.0171 0.0145
Leishmania major protein kinase, putative 0.0162 0.0171 0.0145
Echinococcus granulosus neurogenic locus protein delta 0.0274 0.0602 0.0602
Echinococcus granulosus casein kinase I alpha 0.0209 0.035 0.035
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0247 0.0499 0.0499
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Brugia malayi protein unc-22 0.021 0.0356 0.0356
Echinococcus granulosus epidermal growth factor receptor 0.0463 0.1331 0.1331
Brugia malayi Myb-like DNA-binding domain containing protein 0.0131 0.0049 0.0049
Plasmodium falciparum casein kinase 2, alpha subunit 0.0192 0.0286 0.0261
Echinococcus granulosus cyclin dependent kinase 0.0228 0.0426 0.0426
Echinococcus granulosus c src tyrosine kinase 0.018 0.0241 0.0241
Toxoplasma gondii aurora kinase 0.0225 0.0414 0.0389
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0437 0.1231 0.1231
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0472 0.1367 0.1367
Toxoplasma gondii AGC kinase 0.0217 0.0382 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0122 0.0122
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0576 0.1768
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Trypanosoma cruzi polo-like protein kinase, putative 0.0521 0.1555 0.1533
Trichomonas vaginalis STE family protein kinase 0.0165 0.0181 0.0514
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0303 0.0713 0.0713
Schistosoma mansoni serine/threonine protein kinase 0.0509 0.151 0.151
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0838 0.2775 0.2775
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0425 0.1186 0.1186
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0249 0.0507 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0289 0.0289
Onchocerca volvulus Serine\/threonine kinase homolog 0.0521 0.1555 0.5921
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0142 0.0142
Plasmodium falciparum casein kinase 1 0.0209 0.035 0.0324
Echinococcus granulosus tyrosine protein kinase Srms 0.0518 0.1543 0.1543
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0146 0.011 0.0084
Echinococcus multilocularis fat cadherin tumor suppressor 0.0274 0.0602 0.0602
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0171 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Onchocerca volvulus Slit protein homolog 0.0317 0.0767 0.2897
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0235 0.0451 0.0426
Echinococcus multilocularis mitogen activated protein kinase 3 0.016 0.0164 0.0164
Onchocerca volvulus 0.0357 0.0923 0.3495
Echinococcus multilocularis tyrosine protein kinase Blk 0.0239 0.0466 0.0466
Schistosoma mansoni cell adhesion molecule 0.0155 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0428 0.1197 0.1197
Echinococcus multilocularis Immunoglobulin 0.0516 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.02 0.0318 0.0318
Loa Loa (eye worm) CAMK protein kinase 0.021 0.0356 0.0356
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0249 0.0507 0.0507
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Echinococcus granulosus cGMP dependent protein kinase 1 0.016 0.0163 0.0163
Loa Loa (eye worm) LAD-2 short isoform 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.031 0.0739 0.0739
Loa Loa (eye worm) AUR protein kinase 0.0225 0.0414 0.0414
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0249 0.0507 0.1549
Echinococcus granulosus titin 0.0131 0.0049 0.0049
Trypanosoma brucei Casein kinase II 0.0192 0.0286 0.0261
Leishmania major protein kinase, putative 0.0193 0.0292 0.0266
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0608 0.189 0.189
Brugia malayi RhoGAP domain containing protein 0.0144 0.0101 0.0101
Echinococcus granulosus cyclin dependent kinase 1 0.0228 0.0426 0.0426
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0293 0.0677 0.0677
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Echinococcus granulosus thioredoxin glutathione reductase 0.2711 1 1
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0286 0.0648 0.0648
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0939 0.3168 0.315
Echinococcus multilocularis epidermal growth factor receptor 0.0663 0.2104 0.2104
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0155 0.0142 0.0142
Echinococcus multilocularis casein kinase I alpha 0.0209 0.035 0.035
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0939 0.3168 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.0142 0.0142
Echinococcus multilocularis CDC7 cell division cycle 7 0.0172 0.0209 0.0209
Schistosoma mansoni cell adhesion molecule 0.0688 0.22 0.22
Schistosoma mansoni glutamate synthase 0.0249 0.0507 0.0507
Loa Loa (eye worm) hypothetical protein 0.0208 0.0347 0.0347
Loa Loa (eye worm) AGC/AKT protein kinase 0.0563 0.1718 0.1718
Echinococcus granulosus tyrosine protein kinase Src42A 0.0178 0.0233 0.0233
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0249 0.0507 0.2569
Schistosoma mansoni tyrosine kinase 0.0401 0.109 0.109
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus calcium activated potassium channel 0.0259 0.0545 0.0545
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0644 0.2029 0.2029
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0516 0.1536 0.1536
Entamoeba histolytica PH domain containing protein kinase, putative 0.0316 0.0764 0.3923
Schistosoma mansoni hypothetical protein 0.0197 0.0305 0.0305
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0939 0.3168 0.3168
Echinococcus multilocularis rho associated protein kinase 0.0627 0.1964 0.1964
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0249 0.0507 0.0482
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Schistosoma mansoni tyrosine kinase 0.0123 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0268 0.058 0.058
Echinococcus multilocularis transfer RNA-Phe 0.0148 0.0116 0.0116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0939 0.3168 0.315
Loa Loa (eye worm) hypothetical protein 0.0533 0.1603 0.1603
Brugia malayi Immunoglobulin domain containing protein 0.0155 0.0142 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0416 0.115 0.115
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0453 0.1292 0.1292
Loa Loa (eye worm) cyclin C 0.1221 0.4256 0.4256
Brugia malayi Protein kinase domain containing protein 0.0293 0.0676 0.0676
Schistosoma mansoni septate junction protein 0.0155 0.0142 0.0142
Entamoeba histolytica protein kinase, putative 0.0159 0.0159 0.0738
Entamoeba histolytica protein kinase, putative 0.0225 0.0414 0.2078
Trichomonas vaginalis AGC family protein kinase 0.0563 0.1718 0.5395
Schistosoma mansoni rap gtpase-activating protein 0.0216 0.0379 0.0379
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Toxoplasma gondii histone kinase SNF1, putative 0.0149 0.0122 0.0096
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.068 0.2169 0.2169
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0235 0.0451 0.0426
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0306 0.0726 0.0702
Brugia malayi hypothetical protein 0.0506 0.1496 0.1496
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0713 0.0713
Schistosoma mansoni titin 0.0285 0.0646 0.0646
Brugia malayi hypothetical protein 0.0216 0.0379 0.0379
Schistosoma mansoni tyrosine kinase 0.0663 0.2104 0.2104
Echinococcus multilocularis neural cadherin 0.0274 0.0602 0.0602
Echinococcus granulosus roundabout 2 0.0303 0.0713 0.0713
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0301 0.0708 0.0593
Schistosoma mansoni serine/threonine protein kinase 0.031 0.0739 0.0739
Brugia malayi basement membrane proteoglycan precursor 0.0155 0.0142 0.0142
Schistosoma mansoni tyrosine kinase 0.0384 0.1028 0.1028
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0301 0.0708 0.0708
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0209 0.0602
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0293 0.0677 0.0677
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0219 0.0391 0.0391
Echinococcus multilocularis 0.0184 0.0254 0.0254
Brugia malayi Protein kinase domain containing protein 0.0235 0.0451 0.0451
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0463 0.1331 0.1331
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Loa Loa (eye worm) hypothetical protein 0.0219 0.0391 0.0391
Echinococcus granulosus growth factor receptor bound protein 2 0.012 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus multilocularis nervana 2 0.0239 0.0468 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Loa Loa (eye worm) hypothetical protein 0.0216 0.0379 0.0379
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0217 0.0382 0.0357
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0939 0.3168 1
Schistosoma mansoni titin 0.0131 0.0049 0.0049
Entamoeba histolytica protein kinase, putative 0.0137 0.0076 0.0297
Loa Loa (eye worm) notch protein 0.0274 0.0602 0.0602
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0379 0.0354
Schistosoma mansoni sulfide quinone reductase 0.0249 0.0507 0.0507
Echinococcus multilocularis protein kinase c epsilon type 0.0393 0.1061 0.1061
Brugia malayi Protein kinase domain containing protein 0.0418 0.1158 0.1158
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0841 0.279 0.279
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0303 0.0713 0.0713
Brugia malayi Hr1 repeat family protein 0.056 0.1706 0.1706
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0247 0.0499 0.0499
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0761 0.2479 0.2479
Entamoeba histolytica serine/threonine protein kinase, putative 0.0149 0.0122 0.0539
Schistosoma mansoni serine/threonine protein kinase 0.0259 0.0545 0.0545
Echinococcus granulosus dual specificity 0.0267 0.0576 0.0576
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Loa Loa (eye worm) hypothetical protein 0.0216 0.0379 0.0379
Schistosoma mansoni sulfide quinone reductase 0.0249 0.0507 0.0507
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0451 0.0451
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0155 0.0144 0.0118
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0249 0.0507 0.0507
Schistosoma mansoni septate junction protein 0.0155 0.0142 0.0142
Plasmodium vivax apical sushi protein, putative 0.0506 0.1496 0.1391
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0131 0.0049 0.0049
Brugia malayi Thioredoxin reductase 0.2711 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Giardia lamblia Kinase, AGC PKA 0.0301 0.0708 0.1923
Entamoeba histolytica protein kinase, putative 0.031 0.0739 0.3793
Schistosoma mansoni notch 0.0274 0.0602 0.0602
Echinococcus granulosus activin receptor type 0.0125 0.0026 0.0026
Onchocerca volvulus Putative titin 0.0131 0.0049 0.0146
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0939 0.3168 0.315
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.016 0.0163 0.0137
Brugia malayi Protein kinase domain containing protein 0.0159 0.0159 0.0159
Loa Loa (eye worm) TK/ALK protein kinase 0.029 0.0664 0.0664
Loa Loa (eye worm) CDC7 protein kinase 0.0172 0.0209 0.0209
Echinococcus granulosus dual specificity protein kinase clk2 0.0296 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0317 0.0767 0.0767
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0239 0.0466 0.0466
Brugia malayi casein kinase I 0.0209 0.035 0.035
Loa Loa (eye worm) AUR protein kinase 0.0225 0.0414 0.0414
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0173 0.0214 0.0214
Brugia malayi hypothetical protein 0.0126 0.003 0.003
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0453 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0506 0.1496 0.1496
Echinococcus multilocularis cyclin dependent kinase 5 0.0228 0.0426 0.0426
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0155 0.0144 0.0118
Schistosoma mansoni tyrosine kinase 0.0577 0.1769 0.1769
Echinococcus multilocularis serine:threonine protein kinase N2 0.056 0.1706 0.1706
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0116 0.0116
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0149 0.0122 0.0122
Echinococcus multilocularis mitogen activated protein kinase 11 0.0306 0.0726 0.0726
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0306 0.0726 0.0702
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0939 0.3168 0.315
Plasmodium falciparum glycogen synthase kinase 3 0.0247 0.0499 0.0474
Toxoplasma gondii casein kinase I 0.0209 0.035 0.0324
Leishmania major hypothetical protein, conserved 0.0249 0.0507 0.0482
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Entamoeba histolytica protein kinase, putative 0.0196 0.0301 0.1484
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0162 0.0171 0.0799
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0387 0.1037 0.1037
Plasmodium falciparum protein serine/threonine kinase-1 0.0296 0.0685 0.0661
Echinococcus granulosus serine:threonine kinase SAD 1 0.0149 0.0122 0.0122
Echinococcus multilocularis tyrosine protein kinase 0.0293 0.0676 0.0676
Echinococcus multilocularis expressed protein 0.0159 0.0159 0.0159
Echinococcus granulosus epidermal growth factor receptor 0.0663 0.2104 0.2104
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0147 0.0406
Trichomonas vaginalis AGC family protein kinase 0.0262 0.0555 0.1701
Schistosoma mansoni hypothetical protein 0.0249 0.0507 0.0507
Loa Loa (eye worm) programmed cell death 8 0.0249 0.0507 0.0507
Echinococcus granulosus c4b binding protein beta chain 0.0506 0.1496 0.1496
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0217 0.0382 0.0382
Echinococcus granulosus serine:threonine protein kinase 0.0219 0.0391 0.0391
Echinococcus granulosus cyclin dependent kinase 5 0.0228 0.0426 0.0426
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0228 0.0426 0.0426
Echinococcus granulosus mitogen activated protein kinase 11 0.0306 0.0726 0.0726
Trichomonas vaginalis AGC family protein kinase 0.0225 0.0414 0.1253
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0499 0.1524
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0159 0.0159
Toxoplasma gondii rhoptry neck protein RON9 0.0506 0.1496 0.1474
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0122 0.0325
Entamoeba histolytica protein kinase domain containing protein 0.0235 0.0451 0.2275
Echinococcus granulosus ephrin type A receptor 4 A 0.0186 0.0264 0.0264
Brugia malayi Protein kinase domain containing protein 0.0296 0.0685 0.0685
Brugia malayi Protein kinase domain containing protein 0.0387 0.1037 0.1037
Loa Loa (eye worm) thioredoxin reductase 0.2711 1 1
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0192 0.0286 0.0286
Brugia malayi Cyclin C 0.1221 0.4256 0.4256
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Brugia malayi p70 ribosomal S6 kinase beta 0.0549 0.1662 0.1662
Schistosoma mansoni protein kinase C mu 0.0419 0.1162 0.1162
Schistosoma mansoni vav2 0.0159 0.0158 0.0158
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0516 0.1536 0.1536
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0209 0.035 0.035
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0249 0.0507 0.0507
Echinococcus granulosus protein kinase c iota type 0.0551 0.167 0.167
Trichomonas vaginalis CMGC family protein kinase 0.0192 0.0286 0.0847
Echinococcus granulosus aurora kinase A 0.0225 0.0414 0.0414
Echinococcus granulosus c-Jun N-terminal kinases 0.0509 0.151 0.151
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0159 0.0159 0.0133
Echinococcus multilocularis titin 0.0131 0.0049 0.0049
Giardia lamblia Kinase, CMGC CK2 0.0192 0.0286 0.054
Brugia malayi Immunoglobulin I-set domain containing protein 0.0303 0.0713 0.0713
Entamoeba histolytica protein kinase domain containing protein 0.0267 0.0576 0.2932
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0242 0.0479 0.0479
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0209 0.0602
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0521 0.1555 0.1555
Brugia malayi Protein kinase domain containing protein 0.0126 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.0156 0.0147 0.0147
Echinococcus granulosus homeodomain interacting protein kinase 3 0.039 0.1051 0.1051
Entamoeba histolytica protein kinase 2, putative 0.0301 0.0708 0.3626
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0225 0.0414 0.0296
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0414 0.0414
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0249 0.0507 0.1265
Loa Loa (eye worm) hypothetical protein 0.0608 0.189 0.189
Loa Loa (eye worm) hypothetical protein 0.0357 0.0923 0.0923
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0235 0.0451 0.0426
Brugia malayi serine/threonine-protein kinase PAK 7 0.0447 0.127 0.127
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0193 0.0292 0.0292
Plasmodium falciparum apical sushi protein 0.0506 0.1496 0.1474
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0217 0.0382 0.0382
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Echinococcus granulosus protein jagged 1 0.0274 0.0602 0.0602
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Echinococcus multilocularis casein kinase I alpha 0.0209 0.035 0.035
Onchocerca volvulus 0.0565 0.1724 0.657
Echinococcus multilocularis neurogenic locus protein delta 0.0274 0.0602 0.0602
Brugia malayi Animal haem peroxidase family protein 0.0131 0.0049 0.0049
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0125 0.0029 0.0052
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0225 0.0414 0.0414
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.016 0.0164 0.0138
Echinococcus granulosus CDC7 cell division cycle 7 0.0172 0.0209 0.0209
Loa Loa (eye worm) TK protein kinase 0.0239 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0131 0.0049 0.0049
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0295 0.0682 0.0682
Loa Loa (eye worm) hypothetical protein 0.078 0.2552 0.2552
Brugia malayi Immunoglobulin I-set domain containing protein 0.0285 0.0646 0.0646
Loa Loa (eye worm) cyclin domain-containing protein 0.0606 0.1884 0.1884
Trypanosoma brucei protein kinase, putative 0.016 0.0164 0.0138
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0549 0.1662 0.1662
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0267 0.0576 0.0576
Brugia malayi Tyrosine-protein kinase abl-1 0.018 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0217 0.0382 0.0357
Echinococcus multilocularis 0.0295 0.0682 0.0682
Loa Loa (eye worm) thyroid receptor interactor 0.0197 0.0307 0.0307
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0939 0.3168 0.315
Loa Loa (eye worm) hypothetical protein 0.0285 0.0646 0.0646
Echinococcus granulosus netrin receptor unc 5 0.0211 0.0358 0.0358
Echinococcus granulosus C type lectin domian containing protein 0.0506 0.1496 0.1496
Trypanosoma brucei trypanothione reductase 0.2711 1 1
Echinococcus granulosus protein kinase c epsilon type 0.0393 0.1061 0.1061
Schistosoma mansoni ste20-related kinase 0.0395 0.1069 0.1069
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0267 0.0576 0.0551
Loa Loa (eye worm) hypothetical protein 0.0274 0.0602 0.0602
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0101 0.0101
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0235 0.0451 0.0426
Echinococcus multilocularis nervana 2 0.0239 0.0468 0.0468
Plasmodium vivax casein kinase 1, putative 0.0209 0.035 0.0231
Loa Loa (eye worm) hypothetical protein 0.0516 0.1536 0.1536
Schistosoma mansoni cell adhesion molecule 0.0148 0.0116 0.0116
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0416 0.115 0.115
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0149 0.0122 0.0096
Onchocerca volvulus Peroxidasin homolog 0.0131 0.0049 0.0146
Giardia lamblia Kinase, CMGC GSK 0.0247 0.0499 0.1239
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0249 0.0507 0.0507
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0428 0.1197 0.1197
Echinococcus multilocularis serine:threonine protein kinase N2 0.031 0.0739 0.0739
Brugia malayi serine/threonine-protein kinase plk-2 0.0521 0.1555 0.1555
Loa Loa (eye worm) TK/ROR protein kinase 0.0193 0.029 0.029
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0217 0.0382 0.0382
Schistosoma mansoni hypothetical protein 0.0274 0.0602 0.0602
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0437 0.1231 0.1231
Giardia lamblia Kinase, AGC PKA 0.0217 0.0382 0.0856
Echinococcus granulosus serine:threonine protein kinase N2 0.0251 0.0512 0.0512
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Echinococcus multilocularis protein tyrosine kinase 0.055 0.1665 0.1665
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0171 0.0145
Echinococcus granulosus Immunoglobulin 0.0155 0.0142 0.0142
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0267 0.0576 0.0576
Trichomonas vaginalis CMGC family protein kinase 0.016 0.0164 0.046
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.069 0.2207 0.2207
Echinococcus multilocularis hypothetical protein 0.0197 0.0305 0.0305
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0249 0.0507 0.0482
Brugia malayi Furin-like cysteine rich region family protein 0.0663 0.2104 0.2104
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.016 0.0164 0.0164
Brugia malayi Homeodomain interacting protein kinase protein 1 0.039 0.1051 0.1051
Plasmodium falciparum cGMP-dependent protein kinase 0.016 0.0163 0.0137
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0216 0.0379 0.0379
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.031 0.0739 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0761 0.2479 0.2479
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0247 0.0499 0.0499
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0278 0.0619 0.0619
Trichomonas vaginalis CAMK family protein kinase 0.0521 0.1555 0.4877
Echinococcus multilocularis protein jagged 1 0.0274 0.0602 0.0602
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0249 0.0507 0.2569
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0292 0.0865
Trichomonas vaginalis apoptosis inducing factor, putative 0.0249 0.0507 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0685 0.0685
Brugia malayi Protein kinase domain containing protein 0.0555 0.1687 0.1687
Loa Loa (eye worm) TK/FER protein kinase 0.0418 0.1156 0.1156
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0249 0.0507 0.0482
Brugia malayi EGF-like domain containing protein 0.0274 0.0602 0.0602
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0954 0.3226 0.3226
Plasmodium falciparum ferrodoxin reductase-like protein 0.0249 0.0507 0.0482
Brugia malayi Immunoglobulin I-set domain containing protein 0.0533 0.1603 0.1603
Brugia malayi Leucine Rich Repeat family protein 0.0131 0.0051 0.0051
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0209 0.035 0.035
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0149 0.0122 0.0096
Loa Loa (eye worm) hypothetical protein 0.0233 0.0445 0.0445
Entamoeba histolytica protein kinase, putative 0.0159 0.0159 0.0738
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0193 0.0292 0.0266
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0193 0.029 0.029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0131 0.0049 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.0382 0.0382
Echinococcus multilocularis serine:threonine protein kinase 0.0219 0.0391 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0921 0.3097 0.3097
Entamoeba histolytica disulphide oxidoreductase, putative 0.0249 0.0507 0.2569
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0228 0.0426 0.04
Entamoeba histolytica protein kinase, putative 0.0176 0.0223 0.1071
Schistosoma mansoni hypothetical protein 0.0131 0.0049 0.0049
Trichomonas vaginalis CMGC family protein kinase 0.0247 0.0499 0.1524
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0262 0.0555 0.0438
Schistosoma mansoni basigin related 0.0155 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0155 0.0142 0.0142
Brugia malayi Immunoglobulin I-set domain containing protein 0.021 0.0356 0.0356

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 7 % Inhibition of FimC/FimH pilus assembly complex formation in Escherichia coli at 10 uM ChEMBL. 15715464
Inhibition (binding) = 23 % Inhibition of FimC/FimH pilus assembly complex formation in Escherichia coli at 50 uM ChEMBL. 15715464
Inhibition (binding) = 40 % Inhibition of FimC/FimH pilus assembly complex formation in Escherichia coli at 200 uM ChEMBL. 15715464

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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