Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | WEE1 G2 checkpoint kinase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Schistosoma mansoni | sodium/dicarboxylate symporter-related | 0.0172 | 0.2877 | 0.3013 |
Echinococcus multilocularis | Excitatory amino acid transporter | 0.0388 | 0.7294 | 0.7268 |
Leishmania major | protein kinase, putative,serine/threonine protein kinase, putative | 0.0069 | 0.0767 | 0.2015 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0365 | 0.682 | 0.7394 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0365 | 0.682 | 0.7394 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0365 | 0.682 | 0.6789 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0193 | 0.3302 | 0.3485 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.4076 | 0.5588 |
Schistosoma mansoni | glutamate receptor kainate | 0.0215 | 0.3755 | 0.3988 |
Echinococcus multilocularis | neutral amino acid transporter excitatory amino acid transporter | 0.0172 | 0.2877 | 0.2807 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0365 | 0.682 | 0.9342 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0172 | 0.288 | 0.3016 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0041 | 0.0195 | 0.0267 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0572 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Echinococcus multilocularis | excitatory amino acid transporter 2 | 0.0388 | 0.7294 | 0.7268 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0365 | 0.682 | 0.9342 |
Trypanosoma brucei | wee1-like protein kinase | 0.0069 | 0.0767 | 0.1333 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.3302 | 0.4527 |
Echinococcus granulosus | nmda type glutamate receptor | 0.008 | 0.0987 | 0.0898 |
Brugia malayi | cytochrome P450 | 0.0052 | 0.0418 | 0.0446 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0365 | 0.682 | 0.7394 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0172 | 0.288 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Echinococcus granulosus | neutral amino acid transporter A | 0.0388 | 0.7294 | 0.7268 |
Brugia malayi | nuclear receptor RXR | 0.0193 | 0.3302 | 0.4453 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0041 | 0.0195 | 0.0098 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0172 | 0.288 | 0.3948 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0041 | 0.0195 | 0.0098 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0172 | 0.288 | 0.281 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0172 | 0.288 | 0.3782 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0365 | 0.682 | 0.6789 |
Echinococcus granulosus | expressed protein | 0.0364 | 0.6804 | 0.6773 |
Brugia malayi | steroid hormone receptor | 0.0365 | 0.682 | 0.9342 |
Onchocerca volvulus | 0.0172 | 0.288 | 0.3782 | |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 0.0767 | 0.2015 |
Echinococcus granulosus | sodium:dicarboxylate symporter | 0.0388 | 0.7294 | 0.7268 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.3302 | 0.4527 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0041 | 0.0195 | 0.0267 |
Loa Loa (eye worm) | cytochrome P450 | 0.0052 | 0.0418 | 0.0573 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0172 | 0.288 | 0.281 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0365 | 0.682 | 0.9351 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0365 | 0.682 | 0.9351 |
Echinococcus multilocularis | atrial natriuretic peptide receptor | 0.0041 | 0.0195 | 0.0098 |
Echinococcus multilocularis | sodium:dicarboxylate symporter | 0.0172 | 0.2877 | 0.2807 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0365 | 0.682 | 0.6789 |
Schistosoma mansoni | thyroid hormone receptor | 0.0365 | 0.682 | 0.7394 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0365 | 0.682 | 0.9351 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0193 | 0.3302 | 0.3236 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0215 | 0.3755 | 0.5082 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0572 | 0.0452 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.052 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0365 | 0.682 | 0.9342 |
Brugia malayi | nuclear receptor NHR-67 | 0.0172 | 0.288 | 0.3866 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0215 | 0.3755 | 0.5082 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0365 | 0.682 | 0.9342 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0193 | 0.3302 | 0.4527 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0172 | 0.288 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Brugia malayi | hypothetical protein | 0.0172 | 0.288 | 0.3866 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0256 | 0.4588 | 0.4914 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0572 | 0.1328 |
Brugia malayi | nuclear receptor NHR-88 | 0.0172 | 0.288 | 0.3866 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0172 | 0.288 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Schistosoma mansoni | nuclear receptor | 0.0172 | 0.288 | 0.3016 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0172 | 0.288 | 0.3948 |
Echinococcus granulosus | atrial natriuretic peptide receptor | 0.0041 | 0.0195 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0256 | 0.4588 | 0.4535 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0172 | 0.288 | 0.3016 |
Schistosoma mansoni | tyrosine kinase | 0.0041 | 0.0195 | 0.0033 |
Echinococcus granulosus | tyrosine kinase | 0.0041 | 0.0195 | 0.0098 |
Brugia malayi | Excitatory amino acid transporter | 0.0388 | 0.7294 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0256 | 0.4588 | 0.4535 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0365 | 0.682 | 0.9342 |
Schistosoma mansoni | thyroid hormone receptor | 0.0365 | 0.682 | 0.7394 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0041 | 0.0195 | 0.0098 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0041 | 0.0195 | 0.0033 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0365 | 0.682 | 0.9342 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0172 | 0.288 | 0.281 |
Leishmania major | cytochrome p450-like protein | 0.0052 | 0.0418 | 0.0787 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0172 | 0.288 | 0.3866 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0365 | 0.682 | 0.9342 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | neutral amino acid transporter A | 0.0388 | 0.7294 | 0.7268 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0172 | 0.288 | 0.281 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0365 | 0.682 | 0.9342 |
Echinococcus multilocularis | sodium:dicarboxylate symporter | 0.0388 | 0.7294 | 0.7268 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0069 | 0.0767 | 0.2015 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.018 | 0.3035 | 0.4161 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.008 | 0.0987 | 0.0898 |
Brugia malayi | Cytochrome P450 family protein | 0.018 | 0.3035 | 0.4083 |
Brugia malayi | Cytochrome P450 family protein | 0.018 | 0.3035 | 0.4083 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0215 | 0.3755 | 0.3988 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0365 | 0.682 | 0.6789 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0172 | 0.288 | 0.3866 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0172 | 0.288 | 0.3866 |
Echinococcus multilocularis | Ribosomal protein S1, RNA binding domain | 0.008 | 0.0987 | 0.0898 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0052 | 0.0418 | 0.5 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0041 | 0.0195 | 0.0135 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0365 | 0.682 | 0.6789 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0052 | 0.0418 | 0.0787 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0365 | 0.682 | 0.7394 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0365 | 0.682 | 0.9351 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0041 | 0.0195 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0215 | 0.3755 | 0.3693 |
Brugia malayi | hypothetical protein | 0.0231 | 0.4076 | 0.5529 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.3302 | 0.4527 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0572 | 0.0223 |
Echinococcus granulosus | Ribosomal protein S1 RNA binding domain | 0.008 | 0.0987 | 0.0898 |
Echinococcus multilocularis | neutral amino acid transporter excitatory amino acid transporter | 0.0388 | 0.7294 | 0.7268 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0365 | 0.682 | 0.7394 |
Trypanosoma cruzi | cytochrome P450, putative | 0.018 | 0.3035 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0365 | 0.682 | 0.6789 |
Echinococcus granulosus | glutamate receptor 2 | 0.0256 | 0.4588 | 0.4535 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0193 | 0.3302 | 0.4453 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0052 | 0.0418 | 0.0573 |
Loa Loa (eye worm) | CYP4Cod1 | 0.018 | 0.3035 | 0.4161 |
Mycobacterium tuberculosis | Probable C4-dicarboxylate-transport transmembrane protein DctA | 0.0388 | 0.7294 | 1 |
Schistosoma mansoni | protein kinase | 0.0041 | 0.0195 | 0.0033 |
Schistosoma mansoni | nuclear hormone receptor | 0.0172 | 0.288 | 0.3016 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0215 | 0.3755 | 0.3693 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0215 | 0.3755 | 0.3693 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0052 | 0.0418 | 0.0787 |
Treponema pallidum | glutamate/aspartate transporter | 0.0172 | 0.2877 | 0.5 |
Schistosoma mansoni | nuclear receptor | 0.0172 | 0.288 | 0.3016 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Schistosoma mansoni | nuclear hormone receptor | 0.0172 | 0.288 | 0.3016 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0172 | 0.288 | 0.281 |
Onchocerca volvulus | 0.0172 | 0.288 | 0.3782 | |
Schistosoma mansoni | glutamate receptor AMPA | 0.0215 | 0.3755 | 0.3988 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0344 | 0.6399 | 0.6363 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0041 | 0.0195 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0323 | 0.0313 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.008 | 0.0987 | 0.0898 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.052 | 1 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.048 | 0.9166 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0176 | 0.2962 | 0.2893 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0172 | 0.288 | 0.281 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0365 | 0.682 | 0.7394 |
Leishmania major | cytochrome p450-like protein | 0.0052 | 0.0418 | 0.0787 |
Schistosoma mansoni | zinc finger protein | 0.0172 | 0.288 | 0.3016 |
Onchocerca volvulus | 0.0047 | 0.0323 | 0.0181 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0572 | 0.0587 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0041 | 0.0195 | 0.0033 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0365 | 0.682 | 0.9342 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.4076 | 0.4018 |
Schistosoma mansoni | nuclear hormone receptor | 0.0365 | 0.682 | 0.7394 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.0049 | 0.5 |
Brugia malayi | hypothetical protein | 0.0193 | 0.3302 | 0.4453 |
Trypanosoma cruzi | cytochrome P450, putative | 0.018 | 0.3035 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0052 | 0.0418 | 0.0787 |
Brugia malayi | nuclear receptor RXR | 0.0172 | 0.288 | 0.3866 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0036 | 0.0097 | 0.0133 |
Echinococcus multilocularis | neutral amino acid transporter A | 0.0388 | 0.7294 | 0.7268 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0193 | 0.3302 | 0.3236 |
Brugia malayi | Guanylyl cyclase protein 23 | 0.0041 | 0.0195 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0215 | 0.3755 | 0.5148 |
Echinococcus multilocularis | expressed protein | 0.0364 | 0.6804 | 0.6773 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0365 | 0.682 | 0.6789 |
Schistosoma mansoni | coup transcription factor | 0.0365 | 0.682 | 0.7394 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0365 | 0.682 | 0.9351 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0172 | 0.288 | 0.281 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0215 | 0.3755 | 0.3988 |
Brugia malayi | ecdysone receptor | 0.0172 | 0.288 | 0.3866 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.052 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0172 | 0.288 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0195 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0365 | 0.682 | 0.9342 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0365 | 0.682 | 0.6789 |
Brugia malayi | nuclear hormone receptor | 0.0172 | 0.288 | 0.3866 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0041 | 0.0195 | 0.0267 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0365 | 0.682 | 0.9342 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0365 | 0.682 | 0.9351 |
Echinococcus granulosus | excitatory amino acid transporter 2 | 0.0388 | 0.7294 | 0.7268 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0172 | 0.288 | 0.3948 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0323 | 0.0175 |
Echinococcus granulosus | Excitatory amino acid transporter | 0.0388 | 0.7294 | 0.7268 |
Loa Loa (eye worm) | glutamate receptor | 0.0041 | 0.0195 | 0.0267 |
Schistosoma mansoni | cytochrome P450 | 0.0052 | 0.0418 | 0.0281 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0323 | 0.0175 |
Onchocerca volvulus | 0.0365 | 0.682 | 0.9333 | |
Leishmania major | cytochrome p450-like protein | 0.018 | 0.3035 | 1 |
Loa Loa (eye worm) | metabotropic glutamate receptor 8 | 0.0041 | 0.0195 | 0.0267 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0365 | 0.682 | 0.9342 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0344 | 0.6399 | 0.6363 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0365 | 0.682 | 0.9342 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0041 | 0.0195 | 0.0135 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0365 | 0.682 | 0.9342 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0041 | 0.0195 | 0.0098 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0365 | 0.682 | 0.6789 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0041 | 0.0195 | 0.0098 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.018 | 0.3035 | 0.4161 |
Brugia malayi | conserved hypotetical protein | 0.0172 | 0.288 | 0.3866 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Echinococcus multilocularis | tyrosine kinase | 0.0041 | 0.0195 | 0.0098 |
Schistosoma mansoni | sodium/dicarboxylate symporter-related | 0.0172 | 0.2877 | 0.3013 |
Schistosoma mansoni | tyrosine kinase | 0.0041 | 0.0195 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0365 | 0.682 | 0.7394 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0215 | 0.3755 | 0.3988 |
Loa Loa (eye worm) | excitatory amino acid transporter | 0.0388 | 0.7294 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0572 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0193 | 0.3302 | 0.3485 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.3302 | 0.4527 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0041 | 0.0195 | 0.0098 |
Brugia malayi | hypothetical protein | 0.0172 | 0.288 | 0.3866 |
Echinococcus multilocularis | NMDA receptor | 0.0344 | 0.6399 | 0.6363 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0572 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.3302 | 0.4527 |
Loa Loa (eye worm) | RGC/RGC protein kinase | 0.0041 | 0.0195 | 0.0267 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0365 | 0.682 | 0.7394 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.1978 | 0.2712 |
Brugia malayi | ecdysteroid receptor | 0.0365 | 0.682 | 0.9342 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0365 | 0.682 | 0.6789 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0572 | 0.0452 |
Echinococcus granulosus | FTZ F1 alpha | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0256 | 0.4588 | 0.4535 |
Echinococcus granulosus | Excitatory amino acid transporter | 0.0388 | 0.7294 | 0.7268 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0365 | 0.682 | 0.9342 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0572 | 0.0587 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0041 | 0.0195 | 0.0098 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0172 | 0.288 | 0.281 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0041 | 0.0195 | 0.0135 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0365 | 0.682 | 0.7394 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0034 | 0.0049 | 0.5 |
Echinococcus granulosus | excitatory amino acid transporter 3 | 0.0388 | 0.7294 | 0.7268 |
Echinococcus multilocularis | 0.0052 | 0.0418 | 0.0324 | |
Brugia malayi | tailless protein | 0.0172 | 0.288 | 0.3866 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0172 | 0.288 | 0.3016 |
Echinococcus granulosus | glutamate receptor 2 | 0.0176 | 0.2962 | 0.2893 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0172 | 0.288 | 0.3866 |
Brugia malayi | nuclear hormone receptor | 0.0365 | 0.682 | 0.9342 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.4076 | 0.4018 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.052 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.0987 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0195 | 0.0267 |
Echinococcus granulosus | excitatory amino acid transporter 2 | 0.0388 | 0.7294 | 0.7268 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0041 | 0.0195 | 0.0098 |
Echinococcus granulosus | neutral amino acid transporter | 0.0388 | 0.7294 | 0.7268 |
Chlamydia trachomatis | glutamate symporter | 0.0388 | 0.7294 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0365 | 0.682 | 0.9351 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0215 | 0.3755 | 0.5148 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0572 | 0.0587 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.052 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0365 | 0.682 | 0.6789 |
Echinococcus multilocularis | Excitatory amino acid transporter | 0.0388 | 0.7294 | 0.7268 |
Echinococcus multilocularis | excitatory amino acid transporter 2 | 0.0388 | 0.7294 | 0.7268 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 0.0767 | 0.2015 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0041 | 0.0195 | 0.0135 |
Wolbachia endosymbiont of Brugia malayi | Na+/H+-dicarboxylate symporter | 0.0388 | 0.7294 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.682 | 0.9351 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0418 | 0.0281 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0172 | 0.288 | 0.3866 |
Onchocerca volvulus | Excitatory amino acid transporter homolog | 0.0388 | 0.7294 | 1 |
Brugia malayi | hypothetical protein | 0.0193 | 0.3302 | 0.4453 |
Echinococcus multilocularis | excitatory amino acid transporter 3 | 0.0388 | 0.7294 | 0.7268 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0365 | 0.682 | 0.9333 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.008 | 0.0987 | 0.0898 |
Trypanosoma brucei | cytochrome P450, putative | 0.018 | 0.3035 | 1 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0344 | 0.6399 | 0.6363 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0052 | 0.0418 | 0.0324 |
Treponema pallidum | glutamate transporter | 0.0172 | 0.2877 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0365 | 0.682 | 0.9333 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0193 | 0.3302 | 0.4453 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0172 | 0.288 | 0.3866 |
Schistosoma mansoni | solute carrier family 1 (glial high affinity glutamate transporter | 0.0388 | 0.7294 | 0.792 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0344 | 0.6399 | 0.6363 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0365 | 0.682 | 0.6789 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0069 | 0.0767 | 0.2015 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.288 | 0.3948 |
Loa Loa (eye worm) | DR-78 | 0.0172 | 0.288 | 0.3948 |
Echinococcus multilocularis | neutral amino acid transporter A | 0.0388 | 0.7294 | 0.7268 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0052 | 0.0418 | 0.0787 |
Schistosoma mansoni | glutamate receptor kainate | 0.048 | 0.9166 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0365 | 0.682 | 0.9333 |
Brugia malayi | Cytochrome P450 family protein | 0.0052 | 0.0418 | 0.0446 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0365 | 0.682 | 0.9351 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0172 | 0.288 | 0.3782 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.018 | 0.3035 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.0052 | 0.0418 | 0.5 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0195 | 0.0135 |
Echinococcus granulosus | neutral amino acid transporter A | 0.0388 | 0.7294 | 0.7268 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0365 | 0.682 | 0.9342 |
Brugia malayi | Cytochrome P450 family protein | 0.0052 | 0.0418 | 0.0446 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0365 | 0.682 | 0.9342 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.