Detailed information for compound 315393

Basic information

Technical information
  • TDR Targets ID: 315393
  • Name: (5R)-5-hexyl-4-methoxy-5-methylthiophen-2-one
  • MW: 228.351 | Formula: C12H20O2S
  • H donors: 0 H acceptors: 1 LogP: 3.55 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC[C@@]1(C)SC(=O)C=C1OC
  • InChi: 1S/C12H20O2S/c1-4-5-6-7-8-12(2)10(14-3)9-11(13)15-12/h9H,4-8H2,1-3H3/t12-/m1/s1
  • InChiKey: VDDGISXPYCATBW-GFCCVEGCSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (5R)-5-hexyl-4-methoxy-5-methyl-thiophen-2-one
  • (5R)-5-hexyl-4-methoxy-5-methyl-2-thiophenone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0107 0.0577 0.1362
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Brugia malayi Nuclear hormone receptor E75 0.0388 0.2233 0.4644
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Echinococcus granulosus phospholipase D1 0.0108 0.0579 0.067
Schistosoma mansoni microtubule-associated protein tau 0.1451 0.8502 1
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0342 0.1962 0.7044
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0139 0.0761 0.27
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0254 0.0509
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.0696 0.3503
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0107 0.0577 0.2889
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Leishmania major solanesyl-diphosphate synthase, putative 0.0027 0.0103 0.015
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.019 0.0446
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0252 0.0242
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0481 0.2779 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0435 0.2508 0.2949
Entamoeba histolytica phospholipase D, putative 0.0108 0.0579 0.9644
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0042 0.0037
Onchocerca volvulus 0.0052 0.0252 0.0497
Onchocerca volvulus 0.0038 0.0168 0.0321
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0027 0.0103 0.1519
Mycobacterium leprae Probable lipase LipE 0.0038 0.0168 0.3118
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0421 0.6939
Brugia malayi Serotonin receptor 0.0052 0.0252 0.0505
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0095 0.0221
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0027 0.0103 0.0322
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0037 0.0023
Onchocerca volvulus 0.0052 0.0252 0.0497
Brugia malayi ecdysone receptor 0.0388 0.2233 0.4644
Schistosoma mansoni chromobox protein 0.0012 0.0014 0.0015
Echinococcus multilocularis thyroid hormone receptor alpha 0.0823 0.4798 0.4793
Schistosoma mansoni lamin 0.0057 0.0278 0.0325
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0053 0.0199
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0388 0.2233 0.2226
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0823 0.4798 1
Schistosoma mansoni opsin-like receptor 0.0052 0.0252 0.0295
Schistosoma mansoni amine GPCR 0.0052 0.0252 0.0295
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0221 0.0414
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0064 0.0253
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0081 0.01
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0252 0.0295
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0823 0.4798 0.5643
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0039 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0058 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0108 0.025
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0111 0.06 0.059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0388 0.2233 0.2226
Trichomonas vaginalis Ferredoxin 6 0.0023 0.0081 0.0187
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0042 0.0032
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0252 0.0295
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Schistosoma mansoni opsin-like receptor 0.0052 0.0252 0.0295
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0252 0.0505
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0245 0.1389 0.7058
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0252 0.0242
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0197 0.023
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0435 0.2508 0.2501
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Entamoeba histolytica hypothetical protein 0.0038 0.0167 0.2613
Trichomonas vaginalis glucosylceramidase, putative 0.0543 0.3146 0.7446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0013 0.0003
Brugia malayi Dopamine receptor protein 2 0.0052 0.0252 0.0505
Loa Loa (eye worm) nuclear receptor NHR-67 0.0388 0.2233 0.4655
Echinococcus granulosus Nuclear hormone receptor HR96 0.0388 0.2233 0.2618
Schistosoma mansoni hypothetical protein 0.0052 0.0252 0.0295
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Trypanosoma brucei unspecified product 0.002 0.0064 0.0083
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0823 0.4798 0.4793
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0197 0.0187
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0147 0.0137
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0252 0.0295
Echinococcus granulosus tyrosine protein kinase Src64B 0.0039 0.0176 0.0196
Brugia malayi ecdysteroid receptor 0.0823 0.4798 1
Mycobacterium tuberculosis Conserved protein 0.0038 0.0168 0.0787
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0823 0.4798 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0197 0.0187
Echinococcus granulosus neuroligin 0.0012 0.0014 0.0005
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0362 0.2079 0.2444
Echinococcus granulosus Ankyrin 0.0015 0.0033 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Schistosoma mansoni tyrosine kinase 0.0039 0.0176 0.0206
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0823 0.4798 0.4793
Echinococcus granulosus tm gpcr rhodopsin 0.092 0.5367 0.6309
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0823 0.4798 1
Schistosoma mansoni trans-prenyltransferase 0.0027 0.0103 0.012
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0064 0.0054
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0252 0.0242
Mycobacterium tuberculosis Conserved protein 0.0038 0.0168 0.0787
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0388 0.2233 0.2626
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0053 0.0199
Mycobacterium ulcerans oxidoreductase 0.0023 0.0081 0.0242
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.0053 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0221 0.0519
Brugia malayi Cytochrome P450 family protein 0.0059 0.0289 0.0582
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.0053 0.014
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0823 0.4798 1
Giardia lamblia Kinase, CMGC GSK 0.0111 0.06 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0104 0.0557 0.116
Echinococcus granulosus neuropeptide receptor 0.0052 0.0252 0.0285
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0503 0.059
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0351 0.0706
Schistosoma mansoni adrenodoxin 0.0023 0.0081 0.0094
Echinococcus multilocularis serotonin receptor 0.0052 0.0252 0.0242
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Echinococcus multilocularis phospholipase d3 0.002 0.0063 0.0053
Onchocerca volvulus 0.0107 0.0574 0.117
Schistosoma mansoni chromobox protein 0.0012 0.0014 0.0015
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0027 0.0103 0.0215
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0252 0.0285
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0121 0.0655 0.0759
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0189 0.0211
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0772 0.4493 0.9362
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0168 0.2616
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0121 0.0655 0.2317
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0324
Schistosoma mansoni DNA polymerase eta 0.002 0.0064 0.0073
Mycobacterium ulcerans hypothetical protein 0.0118 0.0639 0.2261
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0176 0.0196
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0823 0.4798 0.5639
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Onchocerca volvulus 0.0253 0.1437 0.2974
Trypanosoma brucei ubiquitin-protein ligase, putative 0.004 0.0181 0.0346
Echinococcus multilocularis conserved hypothetical protein 0.0723 0.4206 0.42
Giardia lamblia Farnesyl diphosphate synthase 0.0107 0.0577 0.9575
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0252 0.0242
Trypanosoma cruzi Emopamil binding protein, putative 0.0144 0.0793 0.1698
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0252 0.0242
Entamoeba histolytica hypothetical protein 0.0038 0.0167 0.2613
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0168 0.0787
Echinococcus granulosus chromobox protein 1 0.0012 0.0014 0.0005
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0252 0.0525
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0039 0.0176 0.0166
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0252 0.0242
Schistosoma mansoni lamin 0.0057 0.0278 0.0325
Loa Loa (eye worm) hypothetical protein 0.0253 0.1437 0.2995
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0042 0.0032
Onchocerca volvulus 0.0388 0.2233 0.4639
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0252 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0252 0.0285
Chlamydia trachomatis endonuclease IV 0.0081 0.0421 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.2808
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.2808
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0027 0.0103 0.1371
Echinococcus multilocularis dna polymerase kappa 0.002 0.0064 0.0054
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.0053 0.014
Brugia malayi Nuclear hormone receptor-like 1 0.0435 0.2508 0.5217
Loa Loa (eye worm) phospholipase D 0.002 0.0063 0.0132
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0023 0.0081 0.0169
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0123 0.0235
Schistosoma mansoni biogenic amine receptor 0.0052 0.0252 0.0295
Schistosoma mansoni cpg binding protein 0.0064 0.032 0.0375
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Mycobacterium ulcerans oxidoreductase 0.0023 0.0081 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0823 0.4798 1
Schistosoma mansoni myosin xvIII 0.0052 0.0252 0.0295
Brugia malayi nuclear hormone receptor family member nhr-6 0.0388 0.2233 0.4644
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0252 0.0242
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0053 0.0037
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0111 0.06 0.0704
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0105 0.0112
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0111 0.06 0.1264
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0252 0.0242
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0042 0.0032
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0023 0.0081 0.0149
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.0053 0.014
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.001 0.001
Treponema pallidum sodium- and chloride- dependent transporter 0.0253 0.1437 1
Brugia malayi hypothetical protein 0.0017 0.0045 0.0074
Schistosoma mansoni gliotactin 0.0012 0.0014 0.0015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0823 0.4798 0.5639
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0111 0.06 0.125
Brugia malayi CHD4 protein 0.0015 0.0035 0.0052
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0038 0.0168 0.0349
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0435 0.2508 0.2949
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0091 0.0477 0.7905
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0027 0.0103 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0189 0.0179
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0053 0.0037
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0023 0.0081 0.0343
Echinococcus granulosus sex peptide receptor 0.0052 0.0252 0.0285
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0183 0.1021 0.1012
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0823 0.4798 0.5643
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0023 0.0081 0.014
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0053 0.0199
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0181 0.0324
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0069 0.0281
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0252 0.0295
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.019 0.0223
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0221 0.0259
Brugia malayi hypothetical protein 0.0038 0.0167 0.0329
Loa Loa (eye worm) norepinephrine transporter 0.0253 0.1437 0.2995
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0109 0.0254
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0081 0.0421 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0252 0.0285
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0023 0.0081 0.0957
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0823 0.4798 0.4793
Leishmania major farnesyl pyrophosphate synthase 0.0107 0.0577 0.1213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.013 0.0302
Onchocerca volvulus 0.0057 0.0278 0.0551
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0823 0.4798 0.5643
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0032 0.0026
Onchocerca volvulus 0.0052 0.0252 0.0497
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Onchocerca volvulus 0.0043 0.0197 0.0382
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0095 0.0221
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0221 0.0414
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0252 0.0285
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0173 0.0163
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0164 0.0384
Trichomonas vaginalis Ferredoxin 7 0.0023 0.0081 0.0187
Echinococcus multilocularis neuropeptide s receptor 0.0538 0.3115 0.3109
Trichomonas vaginalis Ferredoxin 4 0.0023 0.0081 0.0187
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0388 0.2233 0.2618
Brugia malayi nuclear receptor NHR-88 0.0823 0.4798 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0253 0.1437 0.1689
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0042 0.0087
Brugia malayi Dopamine receptor protein 1 0.0052 0.0252 0.0505
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0168 0.0392
Echinococcus multilocularis chromobox protein 1 0.0012 0.0014 0.0004
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0099 0.0163
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0197 0.0187
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0136 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0032 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0388 0.2233 0.2626
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0194 0.0227
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Treponema pallidum hypothetical protein 0.0118 0.0639 0.4019
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0023 0.0081 0.0242
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0064 0.0146
Trypanosoma brucei cardiolipin synthetase, putative 0.0038 0.0165 0.0311
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0144 0.0793 0.1698
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0176 0.0166
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.0362 0.0425
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0189 0.2981
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0107 0.0577 0.8279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0037 0.0082
Toxoplasma gondii ABC1 family protein 0.0038 0.0168 0.2384
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Onchocerca volvulus 0.0052 0.0252 0.0497
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.0696 0.0808
Schistosoma mansoni hypothetical protein 0.0054 0.0263 0.0308
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0064 0.0083
Loa Loa (eye worm) hypothetical protein 0.0435 0.2508 0.5227
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Brugia malayi Melatonin receptor type 1A 0.0052 0.0252 0.0505
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Onchocerca volvulus Protein ultraspiracle homolog 0.0823 0.4798 1
Echinococcus multilocularis protein kinase shaggy 0.0111 0.06 0.059
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0015
Brugia malayi Valyl-tRNA synthetase 0.0012 0.0014 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0388 0.2233 0.4655
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Echinococcus granulosus neuropeptide receptor A26 0.0538 0.3115 0.3657
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) solute carrier family 6 member 4 0.0253 0.1437 0.2995
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0052 0.0252 0.0525
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0164 0.0287
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0245 0.1389 0.4971
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0164 0.0384
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Entamoeba histolytica protein kinase domain containing protein 0.0111 0.06 1
Brugia malayi hypothetical protein 0.0042 0.0189 0.0374
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0726 0.4225 1
Onchocerca volvulus 0.0052 0.0252 0.0497
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0032 0.0038
Trichomonas vaginalis Heterochromatin protein, putative 0.0012 0.0014 0.003
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0253 0.1437 0.2981
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0221 0.0249
Schistosoma mansoni phospholipase D 0.0108 0.0579 0.0679
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Loa Loa (eye worm) hypothetical protein 0.0362 0.2079 0.4333
Giardia lamblia Kinase, CMGC GSK 0.0111 0.06 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0168 0.0316
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0181 0.0424
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0394
Brugia malayi protein-tyrosine kinase 0.0036 0.0153 0.0299
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Echinococcus multilocularis RUN 0.0042 0.0189 0.0179
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Echinococcus multilocularis dnaJ subfamily B 0.086 0.5016 0.5011
Toxoplasma gondii hypothetical protein 0.0043 0.0197 0.2808
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0435 0.2508 0.2942
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0027 0.0103 0.011
Echinococcus granulosus neuropeptide receptor 0.0052 0.0252 0.0285
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0039 0.0176 0.0196
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0342 0.1962 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.0053 0.014
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0027 0.0103 0.012
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0823 0.4798 0.4793
Brugia malayi G-protein coupled receptor 0.0052 0.0252 0.0505
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0107 0.0577 0.1233
Schistosoma mansoni netrin receptor unc5 0.0015 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.019 0.0446
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0013 0.0004
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0014 0.0015
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0197 0.0187
Echinococcus granulosus carboxylesterase 5A 0.0071 0.0362 0.0415
Echinococcus granulosus allatostatin A receptor 0.0052 0.0252 0.0285
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0099 0.1448
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0064 0.0061
Schistosoma mansoni hypothetical protein 0.0179 0.0998 0.1173
Loa Loa (eye worm) hypothetical protein 0.0056 0.0272 0.0566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0018 0.0038
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0107 0.0577 0.9611
Leishmania major hypothetical protein, conserved 0.0038 0.0168 0.0294
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.0053 0.014
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Echinococcus multilocularis tyrosine protein kinase HCK 0.0032 0.013 0.012
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0351 0.0713
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0064 0.0083
Onchocerca volvulus Bile acid receptor homolog 0.0823 0.4798 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0035 0.0025
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0252 0.0285
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0053 0.0199
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0252 0.0242
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Brugia malayi sulfakinin receptor protein 0.0052 0.0252 0.0505
Echinococcus granulosus microtubule associated protein 2 0.1451 0.8502 1
Schistosoma mansoni adenoreceptor 0.0052 0.0252 0.0295
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0168 0.0196
Schistosoma mansoni neuropeptide receptor 0.0052 0.0252 0.0295
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0181 0.2844
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0823 0.4798 1
Mycobacterium ulcerans epimerase 0.0021 0.0069 0.0198
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0197 0.022
Leishmania major DNA polymerase eta, putative 0.002 0.0064 0.0061
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.019 0.0345
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Brugia malayi nuclear hormone receptor family member odr-7 0.0388 0.2233 0.4644
Echinococcus granulosus intermediate filament protein 0.0057 0.0278 0.0316
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0823 0.4798 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0221 0.0519
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0252 0.0242
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0027 0.0103 0.011
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0035 0.0039
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.004 0.0181 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.06 0.1415
Brugia malayi Doublecortin family protein 0.0042 0.0189 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Trypanosoma brucei cardiolipin synthetase 0.0038 0.0165 0.0311
Schistosoma mansoni amine GPCR 0.0052 0.0252 0.0295
Brugia malayi hypothetical protein 0.0107 0.0575 0.1179
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0252 0.0285
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0197 0.023
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0168 0.0392
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0823 0.4798 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0123 0.0255
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0107 0.0577 0.1362
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0252 0.0295
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0053 0.0199
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0153 0.0144
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0064 0.0132
Schistosoma mansoni amine GPCR 0.0052 0.0252 0.0295
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0252 0.0505
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0351 0.0402
Brugia malayi Protein kinase domain containing protein 0.0016 0.0039 0.006
Echinococcus multilocularis ecdysone induced protein 78C 0.0823 0.4798 0.4793
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0388 0.2233 0.2226
Brugia malayi Nuclear hormone receptor E75 0.0388 0.2233 0.4644
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0823 0.4798 0.5643
Loa Loa (eye worm) hypothetical protein 0.0435 0.2508 0.5227
Trypanosoma cruzi Emopamil binding protein, putative 0.0144 0.0793 0.1698
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0042 0.0012
Brugia malayi hypothetical protein 0.0468 0.27 0.5619
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0111 0.06 0.0695
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0012 0.0014 0.0004
Echinococcus granulosus protein kinase shaggy 0.0111 0.06 0.0695
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0823 0.4798 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.019 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Plasmodium vivax cardiolipin synthetase, putative 0.0017 0.0045 0.0526
Mycobacterium ulcerans endonuclease IV 0.0081 0.0421 0.1469
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0099 0.0141
Echinococcus granulosus GPCR family 2 0.0017 0.0042 0.0037
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0221 0.0436
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0394 0.2269 0.4728
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0012 0.0014 0.0005
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0252 0.0242
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0252 0.0295
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0136 0.0148
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0252 0.0505
Trichomonas vaginalis Ferredoxin 3 0.0023 0.0081 0.0187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0037 0.0082
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0121 0.0655 0.0646
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0081 0.01
Schistosoma mansoni polycystin 1-related 0.0042 0.0189 0.0221
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.019 0.0181
Brugia malayi follicle stimulating hormone receptor 0.0052 0.0252 0.0505
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0183 0.1021 0.1191
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0153 0.0144
Brugia malayi cytochrome P450 0.0019 0.0053 0.009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0197 0.0187
Echinococcus granulosus dna polymerase kappa 0.002 0.0064 0.0063
Echinococcus multilocularis lamin dm0 0.0057 0.0278 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Brugia malayi Associated with TFs and helicases family protein 0.0012 0.0014 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0107 0.0574 0.1196
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0278 0.0579
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0023 0.0081 0.0149
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0215 0.1213 0.4334
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0069 0.0123
Echinococcus granulosus RUN 0.0042 0.0189 0.0211
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0027 0.0103 0.015
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.0053 0.014
Loa Loa (eye worm) helicase 0.0012 0.0014 0.003
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0351 0.0732
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0042 0.0012
Schistosoma mansoni RAR-like nuclear receptor 0.0823 0.4798 0.5643
Echinococcus granulosus neuropeptide s receptor 0.0538 0.3115 0.3657
Echinococcus multilocularis phospholipase D 0.0095 0.0505 0.0495
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0696 0.2467
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.019 0.0446
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0252 0.0295
Brugia malayi Carboxylesterase family protein 0.0012 0.0014 0.0009
Onchocerca volvulus 0.0052 0.0252 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0164 0.0384
Onchocerca volvulus 0.0043 0.0197 0.0382
Schistosoma mansoni acetylcholinesterase 0.0012 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0252 0.0295
Trypanosoma cruzi cardiolipin synthetase, putative 0.0038 0.0165 0.0288
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0121 0.0655 0.1388
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0017 0.0045 0.0526
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.0411
Schistosoma mansoni neuropeptide receptor 0.0052 0.0252 0.0295
Schistosoma mansoni cytochrome P450 0.0019 0.0053 0.0061
Brugia malayi Steroid receptor seven-up type 2 0.0823 0.4798 1
Echinococcus granulosus lamin 0.0057 0.0278 0.0316
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Trichomonas vaginalis CMGC family protein kinase 0.0111 0.06 0.1415
Entamoeba histolytica protein kinase, putative 0.0032 0.013 0.1976
Plasmodium vivax amine transporter, putative 0.0043 0.0197 0.3119
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0032 0.0022
Leishmania major ferredoxin, 2fe-2s-like protein 0.0023 0.0081 0.01
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0053 0.0199
Echinococcus multilocularis sex peptide receptor 0.0052 0.0252 0.0242
Echinococcus granulosus serotonin receptor 0.0052 0.0252 0.0285
Trichomonas vaginalis hypothetical protein 0.0012 0.0014 0.003
Echinococcus multilocularis serotonin receptor 0.0052 0.0252 0.0242
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0252 0.0242
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0696 0.0818
Brugia malayi hypothetical protein 0.0042 0.0189 0.0374
Brugia malayi Phospholipase D. Active site motif family protein 0.002 0.0063 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0823 0.4798 1
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0064 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0197 0.023
Echinococcus granulosus dnaJ subfamily B 0.086 0.5016 0.5895
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0252 0.0285
Echinococcus granulosus acetylcholinesterase 0.0071 0.0362 0.0415
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0197 0.3119
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Echinococcus multilocularis carboxylesterase 5A 0.0071 0.0362 0.0353
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0189 0.2981
Loa Loa (eye worm) hypothetical protein 0.0038 0.0168 0.0349
Onchocerca volvulus 0.0038 0.0168 0.0321
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0194 0.0227
Schistosoma mansoni nuclear receptor nhr-48 0.0388 0.2233 0.2626
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0168 0.0555
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0039 0.0176 0.0196
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0203 0.0238
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0252 0.0497
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) nuclear hormone receptor 0.0388 0.2233 0.4655
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0252 0.0285
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0252 0.0295
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0252 0.0295
Schistosoma mansoni neuropeptide receptor 0.0052 0.0252 0.0295
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0823 0.4798 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Schistosoma mansoni intermediate filament proteins 0.0057 0.0278 0.0325
Loa Loa (eye worm) hypothetical protein 0.0091 0.0477 0.0994
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0095 0.0221
Echinococcus granulosus ecdysone induced protein 78C 0.0823 0.4798 0.5639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0037 0.0082
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0158 0.0369
Onchocerca volvulus 0.0468 0.27 0.5615
Loa Loa (eye worm) hypothetical protein 0.0435 0.2508 0.5227
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0176 0.0166
Brugia malayi beta-lactamase 0.0038 0.0168 0.0329
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0059 0.0102
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0107 0.0577 0.0568
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0197 0.023
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0252 0.0242
Echinococcus granulosus thyroid hormone receptor alpha 0.0388 0.2233 0.2618
Leishmania major ferredoxin 2fe-2s-like protein 0.0023 0.0081 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Brugia malayi Phospholipase D. Active site motif family protein 0.0038 0.0165 0.0324
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0107 0.0577 0.2035
Leishmania major hypothetical protein, conserved 0.0144 0.0793 0.1698
Onchocerca volvulus 0.006 0.03 0.0597
Echinococcus multilocularis acetylcholinesterase 0.0071 0.0362 0.0353
Mycobacterium ulcerans beta-lactamase 0.0038 0.0168 0.0555
Onchocerca volvulus 0.0052 0.0252 0.0497
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0053 0.0199
Brugia malayi nuclear receptor RXR 0.0388 0.2233 0.4644
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0014 0.0015
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0252 0.0242
Echinococcus multilocularis para nitrobenzyl esterase 0.0012 0.0014 0.0004
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0107 0.0577 0.1362
Trichomonas vaginalis glucosylceramidase, putative 0.0543 0.3146 0.7446
Toxoplasma gondii ferredoxin, putative 0.0023 0.0081 0.1139
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0197 0.022
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0081 0.0421 0.0857
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0168 0.0392
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0027 0.0103 0.1548
Entamoeba histolytica protein kinase, putative 0.0111 0.06 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0018 0.0052 0.0109
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0042 0.0035
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0197 0.023
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0107 0.0577 0.9611
Schistosoma mansoni rab6-interacting 0.0042 0.0189 0.0221
Brugia malayi Death domain containing protein 0.0015 0.0032 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0252 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0823 0.4798 1
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0027 0.0103 0.1459
Onchocerca volvulus 0.0038 0.0168 0.0321
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0053 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0064 0.0132
Echinococcus granulosus BC026374 protein S09 family 0.0012 0.0014 0.0005
Schistosoma mansoni amine GPCR 0.0399 0.2298 0.2702
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0017 0.0045 0.0526
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Trypanosoma brucei cytochrome P450, putative 0.0037 0.0162 0.0303
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0252 0.0295
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0113 0.0607 0.1265
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0252 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Loa Loa (eye worm) hypothetical protein 0.0034 0.0143 0.0297
Loa Loa (eye worm) hypothetical protein 0.0362 0.2079 0.4333
Loa Loa (eye worm) hypothetical protein 0.0017 0.0045 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0168 0.0294
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0252 0.0242
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0064 0.0112
Schistosoma mansoni steroid hormone receptor ad4bp 0.0823 0.4798 0.5643
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.0207
Loa Loa (eye worm) hypothetical protein 0.0021 0.0069 0.0144
Echinococcus multilocularis neuropeptide receptor A26 0.0538 0.3115 0.3109
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0064 0.0061
Echinococcus multilocularis chromobox protein 1 0.0012 0.0014 0.0004
Loa Loa (eye worm) acetylcholinesterase 1 0.0071 0.0362 0.0755
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trichomonas vaginalis helicase, putative 0.0014 0.0024 0.0053
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0252 0.0505
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0158 0.0369
Brugia malayi hypothetical protein 0.0043 0.0197 0.0391
Mycobacterium ulcerans hypothetical protein 0.0038 0.0168 0.0555
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0252 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0039 0.0176 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Brugia malayi Polyprenyl synthetase family protein 0.0027 0.0103 0.0195
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0252 0.0505
Loa Loa (eye worm) steroid hormone receptor 0.0823 0.4798 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.03 0.0624
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.004 0.0181 0.0357
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0173 0.0192
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0252 0.0242
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0039 0.0044
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0557 0.0653
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0696 0.2467
Echinococcus multilocularis acetylcholinesterase 0.0071 0.0362 0.0353
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0252 0.0242
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0398 0.0457
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0595 0.3449 0.3442
Echinococcus granulosus phospholipase D 0.0095 0.0505 0.0583
Schistosoma mansoni zinc finger protein 0.0388 0.2233 0.2626
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0252 0.0285
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.004 0.0181 0.0324
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0012 0.0014 0.018
Loa Loa (eye worm) hypothetical protein 0.0042 0.019 0.0397
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0012 0.0014 0.0029
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0179 0.017
Brugia malayi tailless protein 0.0388 0.2233 0.4644
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0099 0.1448
Trichomonas vaginalis glucosylceramidase, putative 0.0543 0.3146 0.7446
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0099 0.14
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0351 0.0706
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.0696 0.1481
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0053 0.0199
Mycobacterium ulcerans electron transfer protein 0.0023 0.0081 0.0242
Schistosoma mansoni hypothetical protein 0.0179 0.0998 0.1173
Plasmodium falciparum glycogen synthase kinase 3 0.0111 0.06 1
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0069 0.0435
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0221 0.0436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0109 0.0254
Schistosoma mansoni lipoxygenase 0.0108 0.0579 0.068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0017 0.0045 0.0526
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0823 0.4798 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0221 0.0414
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0064 0.0083
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0064 0.0061
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0823 0.4798 0.5643
Onchocerca volvulus 0.0104 0.0557 0.1134
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0221 0.0441
Loa Loa (eye worm) hypothetical protein 0.0038 0.0168 0.0349
Loa Loa (eye worm) hypothetical protein 0.0015 0.0033 0.0069
Schistosoma mansoni lozenge 0.0059 0.0289 0.0339
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0252 0.0285
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0823 0.4798 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0388 0.2233 0.2618
Brugia malayi intracellular kinase 0.0111 0.06 0.1232
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0121 0.0655 0.1347
Loa Loa (eye worm) serotonin transporter b 0.0253 0.1437 0.2995
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0042 0.0037
Brugia malayi hypothetical protein 0.0388 0.2233 0.4644
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.0391
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.0053 0.014
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.0053 0.014
Loa Loa (eye worm) beta-lactamase 0.0038 0.0168 0.0349
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0064 0.0146
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.019 0.2367
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0023 0.0081 0.0123
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0087
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0032 0.0026
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0064 0.0063
Leishmania major hypothetical protein, conserved 0.0026 0.0099 0.0141
Trichomonas vaginalis Ferredoxin 2 0.0023 0.0081 0.0187
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.0053 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0376 0.2158 0.5106
Schistosoma mansoni hypothetical protein 0.0042 0.0189 0.0221
Brugia malayi hypothetical protein 0.0017 0.0044 0.0071
Onchocerca volvulus 0.0111 0.06 0.1224
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.0696 1
Brugia malayi nuclear receptor RXR 0.0435 0.2508 0.5217
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0095 0.0503 0.059
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0032 0.0022
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0182 0.0203
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0176 0.0196
Schistosoma mansoni biogenic amine receptor 0.0052 0.0252 0.0295
Brugia malayi GnHR receptor homolog 0.0052 0.0252 0.0505
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0823 0.4798 0.5643
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0252 0.0242
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0173 0.0361
Onchocerca volvulus 0.0144 0.0793 0.1628
Loa Loa (eye worm) hypothetical protein 0.0468 0.27 0.5628
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0053 0.0199
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0351 0.5754
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0042 0.0032
Treponema pallidum quinoline 2-oxidoreductase 0.0115 0.0623 0.3898
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0219 0.1237 0.2578
Loa Loa (eye worm) CYP4Cod1 0.0037 0.0162 0.0337
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0278 0.056
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0121 0.0655 0.0769
Brugia malayi Nuclear hormone receptor-like 1 0.0435 0.2508 0.5217
Schistosoma mansoni loxhd1 0.0042 0.0189 0.0221
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0053 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0081 0.01
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0252 0.0285
Loa Loa (eye worm) hypothetical protein 0.0057 0.0278 0.0579
Loa Loa (eye worm) hypothetical protein 0.0027 0.0105 0.0218
Echinococcus multilocularis musashi 0.0057 0.0278 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0543 0.3146 0.655
Leishmania major polyprenyl synthase, putative 0.0027 0.0103 0.015
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.004 0.0181 0.0324
Schistosoma mansoni amine GPCR 0.0052 0.0252 0.0295
Echinococcus multilocularis microtubule associated protein 2 0.1451 0.8502 0.85
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0095 0.0503 0.058
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Schistosoma mansoni chromobox protein 0.0012 0.0014 0.0015
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0168 0.0555
Entamoeba histolytica hypothetical protein 0.0038 0.0167 0.2613
Echinococcus granulosus tyrosine protein kinase HCK 0.0032 0.013 0.0141
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0136 0.1925
Leishmania major C-8 sterol isomerase-like protein 0.0772 0.4493 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.0772 0.4493 1
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0111 0.06 0.1264
Mycobacterium tuberculosis Conserved protein 0.0038 0.0168 0.0787
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0037 0.0082
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.019 0.0181
Onchocerca volvulus 0.0052 0.0252 0.0497
Onchocerca volvulus 0.0042 0.0189 0.0365
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.0053 0.014
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0023 0.0081 0.0343
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0197 0.022
Schistosoma mansoni opsin-like receptor 0.0052 0.0252 0.0295
Onchocerca volvulus 0.0052 0.0252 0.0497
Giardia lamblia [2Fe-2S] ferredoxin 0.0023 0.0081 0.0327
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.019 0.0345
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0823 0.4798 1
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0252 0.0285
Brugia malayi Uncoordinated protein 44 0.0015 0.0032 0.0047
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.0391
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0053 0.0037
Brugia malayi ubiquitin conjugating enzyme protein 13 0.004 0.0181 0.0357
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0189 0.0179
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0042 0.0048
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0252 0.0285
Trichomonas vaginalis glucosylceramidase, putative 0.0543 0.3146 0.7446
Echinococcus multilocularis phospholipase D1 0.0108 0.0579 0.0569
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0189 0.0211
Brugia malayi Pre-SET motif family protein 0.0219 0.1237 0.2562
Brugia malayi ORL1-like opioid receptor 0.0052 0.0252 0.0505
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0042 0.0032
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0017 0.0045 0.0052
Loa Loa (eye worm) hypothetical protein 0.0772 0.4493 0.9364
Onchocerca volvulus Glucosylceramidase homolog 0.0356 0.2045 0.4245
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0162 0.0281
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0099 0.1448
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0124 0.0288
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Mycobacterium ulcerans electron transfer protein FdxB 0.0023 0.0081 0.0242
Leishmania major cytochrome p450-like protein 0.0037 0.0162 0.0281
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0042 0.0574
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0052 0.0252 0.0242
Loa Loa (eye worm) hypothetical protein 0.0435 0.2508 0.5227
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0254 0.0509
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.0053 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Brugia malayi AKH receptor 0.0052 0.0252 0.0505
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0053 0.0037
Echinococcus granulosus tyrosine protein kinase Src42A 0.0039 0.0176 0.0196
Toxoplasma gondii hypothetical protein 0.0043 0.0197 0.2808
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0168 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.0543 0.3146 0.7446
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0064 0.0253
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0032 0.0047
Echinococcus granulosus cpg binding protein 0.0064 0.032 0.0365
Brugia malayi RE15519p 0.0052 0.0252 0.0505
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0064 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0136 0.0158
Schistosoma mansoni hypothetical protein 0.0019 0.0053 0.0061
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0772 0.4493 1
Leishmania major cytochrome p450-like protein 0.0019 0.0053 0.0037
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0081 0.0421 0.6939
Schistosoma mansoni glutathione synthetase 0.0027 0.0103 0.012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0388 0.2233 0.2618
Brugia malayi isocitrate dehydrogenase 0.0017 0.0042 0.0066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Echinococcus multilocularis FTZ F1 alpha 0.0823 0.4798 0.4793
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0027 0.0103 0.015
Brugia malayi Nuclear hormone receptor-like 1 0.0823 0.4798 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.0162 0.0533
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0221 0.0414
Echinococcus granulosus tyrosine protein kinase Fyn 0.0039 0.0176 0.0196
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0081 0.0343
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0245 0.1389 0.4971
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Plasmodium vivax SET domain protein, putative 0.0033 0.0136 0.2071
Echinococcus granulosus FTZ F1 alpha 0.0823 0.4798 0.5639
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.004 0.0181 0.0171
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0121 0.0655 0.2317
Loa Loa (eye worm) hypothetical protein 0.0253 0.1437 0.2995
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0252 0.0295
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0053 0.0051
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0543 0.3146 0.7446
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0027 0.0103 0.0195
Brugia malayi beta-lactamase family protein 0.0038 0.0168 0.0329
Loa Loa (eye worm) hypothetical protein 0.0253 0.1437 0.2995
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0147 0.0161
Brugia malayi G-protein coupled receptor 0.0052 0.0252 0.0505
Echinococcus multilocularis tumor protein p63 0.0711 0.4134 0.4128
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.0053 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.018 0.0423
Brugia malayi Dopamine receptor 0.0052 0.0252 0.0505
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.092 0.5367 0.5363
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0053 0.0199
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0023 0.0081 0.1139
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0252 0.0497
Schistosoma mansoni nuclear receptor 0.0388 0.2233 0.2626
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Brugia malayi Cytochrome P450 family protein 0.0019 0.0053 0.009
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0197 0.022
Echinococcus granulosus chromobox protein 2 0.0012 0.0014 0.0005
Echinococcus multilocularis Protein lozenge 0.0059 0.0289 0.028
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0107 0.0577 0.0677
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0052 0.0118
Loa Loa (eye worm) hypothetical protein 0.007 0.0357 0.0745
Brugia malayi Carboxylesterase family protein 0.0071 0.0362 0.0736
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0047
Schistosoma mansoni thyroid hormone receptor 0.0823 0.4798 0.5643
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Brugia malayi Cytochrome P450 family protein 0.0037 0.0162 0.0317
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0388 0.2233 0.2226
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0164 0.0309
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.0053 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0037 0.0082
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.004 0.0181 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0064 0.0061
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0107 0.0577 0.2035
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.0053 0.014
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0252 0.0285
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0252 0.0242
Echinococcus granulosus orexin receptor type 2 0.0052 0.0252 0.0285
Echinococcus granulosus death domain containing protein 0.0015 0.0032 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Schistosoma mansoni nuclear receptor 0.0388 0.2233 0.2626
Brugia malayi hypothetical protein 0.0435 0.2508 0.5217
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0059 0.0073
Schistosoma mansoni cpg binding protein 0.006 0.03 0.0351
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0139 0.0761 0.27
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0189 0.0179
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0252 0.0295
Schistosoma mansoni hypothetical protein 0.0036 0.0156 0.0181
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.0053 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0823 0.4798 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0012 0.0014 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Trichomonas vaginalis aldehyde oxidase, putative 0.0726 0.4225 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0252 0.0285
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0027 0.0103 0.0093
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0197 0.023
Schistosoma mansoni biogenic amine receptor 0.0052 0.0252 0.0295
Loa Loa (eye worm) hypothetical protein 0.0071 0.0362 0.0755
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Echinococcus granulosus tyrosine kinase 0.0036 0.0153 0.0169
Loa Loa (eye worm) TK protein kinase 0.0032 0.013 0.0271
Brugia malayi photoreceptor-specific nuclear receptor 0.0823 0.4798 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0095 0.0221
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0252 0.0242
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0252 0.0242
Loa Loa (eye worm) TK protein kinase 0.0036 0.0153 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.0706 0.0829
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0823 0.4798 0.4793
Echinococcus granulosus phospholipase d3 0.002 0.0063 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0823 0.4798 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0252 0.0525
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0037 0.0076
Brugia malayi Carboxylesterase family protein 0.0071 0.0362 0.0736
Brugia malayi hypothetical protein 0.0026 0.0099 0.0186
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0027 0.0103 0.011
Onchocerca volvulus 0.0052 0.0252 0.0497
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0121 0.0655 0.3289
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Loa Loa (eye worm) hypothetical protein 0.0071 0.0362 0.0755
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0252 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Treponema pallidum hypothetical protein 0.0097 0.0517 0.3099
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0221 0.0211
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.019 0.0377
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0197 0.023
Trypanosoma brucei electron transfer protein, putative 0.0023 0.0081 0.0123
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0726 0.4225 1
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0037 0.0027
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0252 0.0285
Trypanosoma cruzi polyprenyl synthase, putative 0.0027 0.0103 0.015
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.004 0.0181 0.0201
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0023 0.0081 0.1139
Loa Loa (eye worm) polyprenyl synthetase 0.0027 0.0103 0.0215
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0023 0.0081 0.0242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0823 0.4798 1
Onchocerca volvulus 0.0052 0.0252 0.0497
Echinococcus multilocularis Ankyrin 0.0015 0.0033 0.0023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0435 0.2508 0.5227
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0053 0.0199
Brugia malayi hypothetical protein 0.0435 0.2508 0.5217
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0197 0.023
Brugia malayi Heterochromatin protein 1 0.0012 0.0014 0.0009
Onchocerca volvulus 0.0045 0.0207 0.0402
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0252 0.0295
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.0411
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0153 0.0169
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0034
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0168 0.0186
Echinococcus multilocularis dna polymerase eta 0.002 0.0064 0.0054
Onchocerca volvulus 0.0043 0.0197 0.0382
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0053 0.0199
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0027 0.0103 1
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0351 0.0706
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0823 0.4798 0.4793
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0053 0.0199
Loa Loa (eye worm) runx1 0.0059 0.0289 0.0603
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0042 0.0037
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0027 0.0103 0.1519
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0014 0.018
Plasmodium falciparum transporter, putative 0.0043 0.0197 0.3119
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0823 0.4798 1
Echinococcus granulosus dna polymerase eta 0.002 0.0064 0.0063
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0181 0.0377
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0042 0.0035
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0012 0.0014 0.0009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0168 0.0196
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0278 0.0579
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0038 0.0168 0.0349
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.019 0.0223
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0039 0.0176 0.0166
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0254 0.0529
Brugia malayi SRC-1 0.0039 0.0176 0.0347
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0058 0.0132
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0221 0.0461
Echinococcus granulosus g protein coupled receptor 0.0052 0.0252 0.0285
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0197 0.022
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0252 0.0525
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0168 0.0787
Loa Loa (eye worm) SRC-1 0.0039 0.0176 0.0367
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0037 0.0023
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Echinococcus multilocularis cpg binding protein 0.0064 0.032 0.031
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.0014 0.003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0823 0.4798 0.5639
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0053 0.0199
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0168 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Onchocerca volvulus 0.0052 0.0252 0.0497
Trypanosoma cruzi cardiolipin synthetase, putative 0.0038 0.0165 0.0288
Brugia malayi nuclear hormone receptor 0.0823 0.4798 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0042 0.0087
Echinococcus granulosus acetylcholinesterase 0.0071 0.0362 0.0415
Onchocerca volvulus 0.0052 0.0252 0.0497
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.006 0.0051
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0351 0.0728
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0252 0.0295
Echinococcus multilocularis lamin 0.0057 0.0278 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Brugia malayi larval opioid receptor 0.0052 0.0252 0.0505
Echinococcus multilocularis ferredoxin adrenodoxin 0.0023 0.0081 0.0071
Echinococcus multilocularis Chromo domain 0.0012 0.0014 0.0004
Echinococcus granulosus ferredoxin 0.0023 0.0081 0.0084
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0153 0.0144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Echinococcus granulosus tumor protein p63 0.0711 0.4134 0.4856
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0042 0.0066
Echinococcus granulosus serotonin transporter 0.0253 0.1437 0.1681
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0492 0.2847 0.284
Brugia malayi nuclear receptor NHR-88 0.0388 0.2233 0.4644
Schistosoma mansoni hypothetical protein 0.0052 0.0252 0.0295
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0053 0.0734
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0168 0.0329
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.019 0.0181
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0252 0.0525
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0696 0.2467
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0351 0.0342
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0197 0.3119
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0027 0.0103 0.0093
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0252 0.0242
Plasmodium falciparum ferredoxin, putative 0.0023 0.0081 0.1139
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0252 0.0295
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Brugia malayi hypothetical protein 0.0012 0.0014 0.0009
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0252 0.0505
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0064 0.0083
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0252 0.0295
Schistosoma mansoni neuropeptide receptor 0.0052 0.0252 0.0295
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0252 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0168 0.0787
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.019 0.0368
Echinococcus multilocularis serotonin transporter 0.0253 0.1437 0.1429
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0035 0.0072
Mycobacterium ulcerans oxygenase 0.0023 0.0081 0.0242
Loa Loa (eye worm) carboxylesterase 0.0012 0.0014 0.003
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0027 0.0103 0.1519
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0042 0.0032
Echinococcus granulosus Chromo domain 0.0012 0.0014 0.0005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.0696 0.0687
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.006 0.0059
Echinococcus multilocularis GPCR, family 2 0.0017 0.0042 0.0032
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.004 0.0181 0.0377
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.0053 0.014
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0252 0.0285
Echinococcus granulosus g protein coupled receptor 0.0052 0.0252 0.0285
Echinococcus multilocularis BC026374 protein (S09 family) 0.0012 0.0014 0.0004
Entamoeba histolytica phospholipase D, putative 0.0108 0.0579 0.9644
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0207 0.0242
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0189 0.0211
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0105 0.0095
Echinococcus multilocularis neuroligin 0.0012 0.0014 0.0004
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.0206
Brugia malayi chromobox protein homolog 3 0.0012 0.0014 0.0009
Onchocerca volvulus 0.0388 0.2233 0.4639
Loa Loa (eye worm) hypothetical protein 0.0026 0.0099 0.0206
Loa Loa (eye worm) hypothetical protein 0.0042 0.0189 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0362 0.2079 0.4321
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Echinococcus multilocularis nuclear receptor nhr 48 0.0388 0.2233 0.2226
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0027 0.0103 0.015
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0197 0.023
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0053 0.0199
Loa Loa (eye worm) hypothetical protein 0.0033 0.0136 0.0283
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0064 0.084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0197 0.0411
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0075 0.0108
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0823 0.4798 0.5643
Loa Loa (eye worm) hypothetical protein 0.0091 0.0477 0.0994
Echinococcus granulosus hypothetical protein 0.0775 0.4515 0.5305
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0398 0.0389
Trichomonas vaginalis Ferredoxin 1 0.0023 0.0081 0.0187
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0107 0.0577 0.1213
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0032 0.0067
Loa Loa (eye worm) hypothetical protein 0.0435 0.2508 0.5227
Loa Loa (eye worm) hypothetical protein 0.0468 0.27 0.5628
Echinococcus granulosus tm gpcr rhodopsin 0.0595 0.3449 0.405
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0039 0.0034
Onchocerca volvulus 0.0107 0.0574 0.117
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0189 0.0394
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0042 0.0032
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0111 0.06 0.125
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0069 0.0114
Leishmania major cytochrome p450-like protein 0.0019 0.0053 0.0037
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0388 0.2233 0.2626
Plasmodium vivax ferredoxin, putative 0.0023 0.0081 0.1139
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.004 0.0181 0.2844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0164 0.0384
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0156 0.0304
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.015 0.213
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0042 0.0574
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0064 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0252 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0823 0.4798 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0168 0.0349
Loa Loa (eye worm) polyprenyl synthetase 0.0107 0.0577 0.1202
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0053 0.0199
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.001 0.001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0388 0.2233 0.4644
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0168 0.0787
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0342 0.1962 0.7044
Brugia malayi orphan nuclear receptor NR2E1 0.0388 0.2233 0.4644
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0696 0.0818
Schistosoma mansoni thyroid hormone receptor 0.0823 0.4798 0.5643
Brugia malayi Carboxylesterase family protein 0.0012 0.0014 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0064 0.0179
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0252 0.0285
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0221 0.353
Onchocerca volvulus Putative phospholipase D 0.002 0.0063 0.0103
Brugia malayi neuropeptide F receptor 0.0052 0.0252 0.0505
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0053 0.0199
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0167 0.0195
Loa Loa (eye worm) DR-78 0.0388 0.2233 0.4655
Brugia malayi hypothetical protein 0.0388 0.2233 0.4644
Echinococcus granulosus g protein coupled receptor 0.0052 0.0252 0.0285
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0221 0.0519
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0289 0.0602
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0221 0.353
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Schistosoma mansoni rab6-interacting 0.0042 0.0189 0.0221
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0823 0.4798 0.5639
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0027 0.0103 0.1519
Giardia lamblia GTOR 0.0047 0.0221 0.2937
Leishmania major hypothetical protein, conserved 0.0023 0.0081 0.01
Echinococcus granulosus somatostatin receptor 0.0052 0.0252 0.0285
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0042 0.0066
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0164 0.0287
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0053 0.0199
Mycobacterium tuberculosis Possible oxygenase 0.0023 0.0081 0.0343
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0027 0.0103 0.1519
Leishmania major cardiolipin synthetase, putative 0.0017 0.0045 0.0019
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0197 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0064 0.0073
Schistosoma mansoni retinoic acid receptor RXR 0.0927 0.5412 0.6365
Schistosoma mansoni chromobox protein 0.0012 0.0014 0.0015
Brugia malayi CXXC zinc finger family protein 0.006 0.03 0.0605
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0197 0.023
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0042 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.003
Onchocerca volvulus 0.0057 0.0278 0.0551
Schistosoma mansoni hypothetical protein 0.0052 0.0252 0.0295
Echinococcus multilocularis Chromobox protein 3 0.0012 0.0014 0.0004
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0014
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0162 0.0281
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Loa Loa (eye worm) hypothetical protein 0.0388 0.2233 0.4655
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0252 0.0285
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0111 0.06 0.8607
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0027 0.0103 0.0457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0252 0.0242
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0081 0.0421 0.2086
Brugia malayi Cytochrome P450 family protein 0.0037 0.0162 0.0317
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0039 0.0176 0.0166
Schistosoma mansoni cpg binding protein 0.0064 0.032 0.0375
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0139 0.0761 0.3833
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0252 0.0242
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.019 0.0213
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0388 0.2233 0.4639
Echinococcus multilocularis chromobox protein 2 0.0012 0.0014 0.0004
Brugia malayi Carboxylesterase family protein 0.0012 0.0014 0.0009
Toxoplasma gondii ferodoxin FD 0.0023 0.0081 0.1139
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0136 0.0126
Brugia malayi Carboxylesterase family protein 0.0012 0.0014 0.0009
Echinococcus granulosus lamin dm0 0.0057 0.0278 0.0316
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0153 0.0169
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0252 0.0525
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0064 0.0179
Echinococcus granulosus fmrfamide receptor 0.0052 0.0252 0.0285
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) hypothetical protein 0.0038 0.0168 0.0349
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0042 0.0142
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0027 0.0103 0.0457
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0136 0.0158
Echinococcus granulosus geminin 0.0179 0.0998 0.1164
Trichomonas vaginalis chromobox protein, putative 0.0012 0.0014 0.003
Echinococcus multilocularis somatostatin receptor 0.0052 0.0252 0.0242
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0014 0.0015
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0252 0.0505
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0042 0.0468
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Echinococcus multilocularis geminin 0.0179 0.0998 0.0989
Brugia malayi SET domain containing protein 0.0015 0.0029 0.004
Onchocerca volvulus 0.0042 0.0189 0.0365
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.004 0.0181 0.2844
Echinococcus granulosus Adrenodoxin mitochondrial 0.0023 0.0081 0.0084
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.0014 0.0015
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.019 0.0345
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0035 0.0029
Trypanosoma brucei protein kinase, putative 0.0111 0.06 0.1284
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0037 0.0031
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.004 0.0181 0.2576
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0038 0.0165 0.2348
Leishmania major DNA polymerase kappa, putative 0.002 0.0064 0.0061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0037 0.0056
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0027 0.0103 0.0322
Brugia malayi nuclear receptor NHR-67 0.0388 0.2233 0.4644
Brugia malayi G protein-coupled receptor 0.0052 0.0252 0.0505
Loa Loa (eye worm) histone methyltransferase 0.002 0.006 0.0126
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0081 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Brugia malayi Pre-SET motif family protein 0.0033 0.0136 0.0262
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0033 0.0037
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0144 0.0793 0.1698
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0168 0.0392
Onchocerca volvulus 0.0052 0.0252 0.0497
Brugia malayi Phospholipase d protein 1 0.0108 0.0579 0.1188
Loa Loa (eye worm) hypothetical protein 0.0038 0.0168 0.0349
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.2808
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0252 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Entamoeba histolytica protein kinase domain containing protein 0.0111 0.06 1
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0042 0.0066
Loa Loa (eye worm) hypothetical protein 0.007 0.0357 0.0745
Loa Loa (eye worm) hypothetical protein 0.0823 0.4798 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0063 0.0132
Onchocerca volvulus 0.0052 0.0252 0.0497
Schistosoma mansoni coup transcription factor 0.0823 0.4798 0.5643
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0252 0.0242
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0927 0.5412 0.6361
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Chlamydia trachomatis ferredoxin 0.0023 0.0081 0.0957
Brugia malayi M-phase phosphoprotein, mpp8 0.0107 0.0574 0.1178
Trichomonas vaginalis set domain proteins, putative 0.0249 0.1414 0.3345
Loa Loa (eye worm) carboxylesterase 0.0012 0.0014 0.003
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0167 0.0185
Brugia malayi intermediate filament protein 0.0057 0.0278 0.056
Toxoplasma gondii histone lysine methyltransferase SET1 0.0116 0.0625 0.8971
Brugia malayi Protein cec-1. 0.0012 0.0014 0.0009
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0197 0.4045
Trichomonas vaginalis spcc417.12 protein, putative 0.0012 0.0014 0.0029
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0252 0.0525
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0037 0.0041
Schistosoma mansoni histamine h1 receptor 0.0052 0.0252 0.0295
Schistosoma mansoni tyrosine kinase 0.0039 0.0176 0.0206
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0064 0.0083
Loa Loa (eye worm) hypothetical protein 0.0081 0.0421 0.0876
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0012 0.0014 0.018
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0017 0.0045 0.0042
Loa Loa (eye worm) heterochromatin protein 1 0.0012 0.0014 0.003
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0081 0.01
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0168 0.0787
Echinococcus granulosus transcription factor Dp 1 0.004 0.0179 0.02
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0012 0.0014 0.0005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0176 0.0166
Trichomonas vaginalis esterase, putative 0.0038 0.0168 0.0392
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Trichomonas vaginalis glucosylceramidase, putative 0.0356 0.2045 0.4838
Brugia malayi steroid hormone receptor 0.0823 0.4798 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Loa Loa (eye worm) carboxylesterase 0.0071 0.0362 0.0755
Schistosoma mansoni nuclear hormone receptor 0.0388 0.2233 0.2626
Onchocerca volvulus 0.0052 0.0252 0.0497
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0197 0.0391
Echinococcus multilocularis 0.0019 0.0053 0.0043
Onchocerca volvulus 0.025 0.1415 0.2929
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0162 0.0337
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0095 0.0221
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0081 0.01
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0252 0.0285
Mycobacterium ulcerans hypothetical protein 0.0021 0.0069 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.015 0.035
Trypanosoma cruzi polyprenyl synthase, putative 0.0027 0.0103 0.015
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0136 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0014 0.003
Brugia malayi nuclear hormone receptor 0.0388 0.2233 0.4644
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0023 0.0081 0.0071
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0543 0.3146 0.6557
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0027 0.0103 0.0457
Brugia malayi hypothetical protein 0.0052 0.0252 0.0505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0093 0.0216
Schistosoma mansoni hypothetical protein 0.0015 0.0032 0.0036
Mycobacterium ulcerans lipase LipD 0.0038 0.0168 0.0555
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0168 0.0787
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0023 0.0081 0.6178
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Schistosoma mansoni hypothetical protein 0.086 0.5016 0.59
Onchocerca volvulus 0.0052 0.0252 0.0497
Schistosoma mansoni neuroligin 3 (S09 family) 0.0012 0.0014 0.0015
Loa Loa (eye worm) cytochrome P450 0.0019 0.0053 0.011
Echinococcus granulosus nuclear receptor nhr 48 0.0388 0.2233 0.2618
Echinococcus granulosus para nitrobenzyl esterase 0.0012 0.0014 0.0005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0252 0.0295
Loa Loa (eye worm) hypothetical protein 0.0107 0.0575 0.1198
Brugia malayi putative neuropeptide receptor 0.0052 0.0252 0.0505
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0388 0.2233 0.4639
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0107 0.0577 0.0668
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0069 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0024 0.0053
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0027 0.0103 0.0172
Onchocerca volvulus 0.0823 0.4798 1
Schistosoma mansoni lipoxygenase 0.0183 0.1021 0.12
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0039 0.0176 0.0166
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0823 0.4798 0.5639
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0162 0.0337
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0042 0.0468
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.0053 0.014
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0167 0.0158
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0095 0.0221
Plasmodium vivax glycogen synthase kinase 3, putative 0.0111 0.06 1
Entamoeba histolytica hypothetical protein 0.0038 0.0167 0.2613
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0823 0.4798 0.5639
Echinococcus granulosus chromobox protein 1 0.0012 0.0014 0.0005
Brugia malayi beta-lactamase family protein 0.0038 0.0168 0.0329
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0095 0.0221
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0252 0.0242
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0252 0.0525
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Onchocerca volvulus 0.0023 0.0081 0.014
Brugia malayi Serotonin receptor 0.0534 0.3094 0.6441
Echinococcus granulosus Chromobox protein 3 0.0012 0.0014 0.0005
Brugia malayi neuropeptide F receptor 0.0052 0.0252 0.0505
Brugia malayi conserved hypotetical protein 0.0388 0.2233 0.4644
Schistosoma mansoni adrenodoxin 0.0023 0.0081 0.0094
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0095 0.0221
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0099 0.0141
Schistosoma mansoni BC026374 protein (S09 family) 0.0012 0.0014 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0252 0.0295
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0197 0.0391
Brugia malayi Protein K4 0.0017 0.0045 0.0074
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0039 0.0029
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0107 0.0577 0.1213
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.019 0.0213
Loa Loa (eye worm) hypothetical protein 0.0052 0.0252 0.0525
Toxoplasma gondii endonuclease IV APN 0.0081 0.0421 0.6027
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0012 0.0014 0.0015
Trypanosoma brucei Emopamil binding protein, putative 0.0144 0.0793 0.1717
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0095 0.0503 0.0493
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.0053 0.014
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0173 0.0341
Schistosoma mansoni hypothetical protein 0.0038 0.0167 0.0195
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0121 0.0131
Loa Loa (eye worm) hypothetical protein 0.0053 0.0254 0.0529
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0252 0.0295
Schistosoma mansoni sodium/chloride dependent transporter 0.0253 0.1437 0.1689
Trichomonas vaginalis glucosylceramidase, putative 0.0376 0.2158 0.5106
Leishmania major phosphatidylglycerophosphate synthase, putative 0.002 0.0063 0.006
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0027 0.0103 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0168 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0108 0.025
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0144 0.0793 0.1698
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0014 0.003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.019 0.3008
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0168 0.0392
Brugia malayi Polyprenyl synthetase family protein 0.0107 0.0577 0.1184
Schistosoma mansoni hypothetical protein 0.0052 0.0252 0.0295
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0351 0.0412
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0109 0.0254
Loa Loa (eye worm) hypothetical protein 0.0015 0.0032 0.0067
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0064 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0823 0.4798 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0243 0.1375 0.6987
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.0053 0.014
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0053 0.006
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0012 0.0014 0.0015
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0168 0.3118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0164 0.0384
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0039 0.0176 0.0166
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0252 0.0525

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 9.4 ug ml-1 Inhibitory concentration of the compound against MCF-7 breast cancer cells in XTT assay (non radioactive assay) ChEMBL. 15715465
IC50 (functional) = 9.4 ug ml-1 Inhibitory concentration of the compound against MCF-7 breast cancer cells in XTT assay (non radioactive assay) ChEMBL. 15715465
IC50 (functional) = 14 ug ml-1 Inhibitory concentration of the compound against fatty acid synthesis in MCF-7 breast cancer cells ChEMBL. 15715465
IC50 (functional) = 14 ug ml-1 Inhibitory concentration of the compound against fatty acid synthesis in MCF-7 breast cancer cells ChEMBL. 15715465
IC50 (binding) > 50 ug ml-1 Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cells ChEMBL. 15715465
IC50 (binding) > 50 ug ml-1 Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cells ChEMBL. 15715465

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 15715465

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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