Detailed information for compound 316692

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 270.166 | Formula: C12H16BrNO
  • H donors: 1 H acceptors: 0 LogP: 2.78 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2CCNC[C@@H](c2cc1Br)C
  • InChi: 1S/C12H16BrNO/c1-8-7-14-4-3-9-5-12(15-2)11(13)6-10(8)9/h5-6,8,14H,3-4,7H2,1-2H3/t8-/m0/s1
  • InChiKey: HQQAIJWQKAFMGF-QMMMGPOBSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Serotonin receptor Get druggable targets OG5_135430 All targets in OG5_135430
Echinococcus multilocularis conserved hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688
Echinococcus granulosus hypothetical protein Get druggable targets OG5_144688 All targets in OG5_144688

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Onchocerca volvulus Peroxidasin homolog 0.0137 0.0133 0.0432
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Loa Loa (eye worm) programmed cell death 8 0.0265 0.0591 0.0584
Loa Loa (eye worm) hypothetical protein 0.0268 0.0604 0.0597
Echinococcus granulosus casein kinase I delta 0.021 0.0395 0.0395
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0465 0.0465
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0265 0.0591 0.0591
Onchocerca volvulus 0.0126 0.0092 0.027
Echinococcus multilocularis casein kinase I alpha 0.021 0.0395 0.0395
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0171 0.0254 0.0765
Brugia malayi Peroxidasin 0.03 0.0719 0.0701
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Brugia malayi Immunoglobulin I-set domain containing protein 0.0219 0.0425 0.0407
Echinococcus granulosus protein kinase c epsilon type 0.0394 0.1058 0.1058
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0198 0.0198
Schistosoma mansoni cell adhesion molecule 0.0317 0.078 0.078
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0164 0.0228 0.0209
Entamoeba histolytica protein kinase domain containing protein 0.0236 0.0489 0.1772
Echinococcus multilocularis mitogen activated protein kinase 0.0162 0.0221 0.0221
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0284 0.0662 0.2034
Brugia malayi Variant SH3 domain containing protein 0.0118 0.0064 0.0045
Schistosoma mansoni tyrosine kinase 0.0402 0.1087 0.1087
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Onchocerca volvulus Netrin receptor homolog 0.0193 0.0332 0.1228
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Schistosoma mansoni hypothetical protein 0.0154 0.0194 0.0194
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.182 0.6194 0.6191
Trypanosoma cruzi hypothetical protein, conserved 0.0265 0.0591 0.0573
Onchocerca volvulus 0.0218 0.0424 0.1595
Brugia malayi Protein kinase domain containing protein 0.0158 0.0205 0.0187
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0361 0.0937 0.092
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0997 0.3229 1
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0392 0.1049 0.1032
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0291 0.0685 0.2636
Echinococcus granulosus serine:threonine protein kinase TAO1 0.043 0.1185 0.1185
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0118 0.0064 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Echinococcus granulosus hypothetical protein 0.0233 0.0478 0.0478
Schistosoma mansoni tyrosine kinase 0.0333 0.0837 0.0837
Brugia malayi protein-tyrosine kinase 0.024 0.0501 0.0483
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Echinococcus granulosus casein kinase I alpha 0.021 0.0395 0.0395
Onchocerca volvulus 0.0146 0.0165 0.0559
Loa Loa (eye worm) hypothetical protein 0.0268 0.0604 0.0597
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0317 0.078 0.0774
Echinococcus multilocularis calcium dependent protein kinase 0.0131 0.011 0.011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Echinococcus multilocularis N chimaerin 0.0144 0.0157 0.0157
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0162 0.0222 0.0177
Schistosoma mansoni tyrosine kinase 0.0362 0.0943 0.0943
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Giardia lamblia Kinase, CMGC GSK 0.0249 0.0534 0.1414
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0179 0.0282 0.0282
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0997 0.3229 1
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0425 0.0425
Brugia malayi Protein kinase domain containing protein 0.0709 0.2191 0.2176
Trypanosoma cruzi cdc2-related kinase 3 0.023 0.0465 0.0447
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0155 0.0195 0.0195
Plasmodium vivax serine/threonine kinase-1, putative 0.0297 0.0708 0.0664
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0126 0.009 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus 0.0537 0.1571 0.6174
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0997 0.3229 1
Echinococcus granulosus Down syndrome cell adhesion molecule 0.018 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus 0.0537 0.1571 0.6174
Brugia malayi Protein kinase domain containing protein 0.0311 0.0759 0.0741
Loa Loa (eye worm) cyclin C 0.1709 0.5793 0.579
Trypanosoma brucei cdc2-related kinase 1 0.023 0.0465 0.0375
Echinococcus multilocularis nervana 2 0.0239 0.0498 0.0498
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0219 0.0425 0.0335
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0157 0.0204 0.0112
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Onchocerca volvulus 0.0126 0.0092 0.027
Brugia malayi Protein kinase domain containing protein 0.0236 0.0489 0.0471
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0195 0.034 0.034
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Brugia malayi phosphoinositide-dependent protein kinase I 0.0158 0.0205 0.0187
Loa Loa (eye worm) hypothetical protein 0.03 0.0719 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0221 0.0221
Echinococcus granulosus tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Giardia lamblia Thioredoxin reductase 0.0265 0.0591 0.1596
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0127 0.0096 0.0077
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0297 0.0708 0.069
Leishmania major protein kinase, putative 0.0195 0.034 0.0249
Echinococcus granulosus fibropellin Ia 0.0291 0.0685 0.0685
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0219 0.0425 0.0407
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0216 0.0415 0.0415
Brugia malayi Sex muscle abnormal protein 5 0.0118 0.0064 0.0045
Schistosoma mansoni protein kinase 0.0839 0.2658 0.2658
Brugia malayi Protein kinase domain containing protein 0.0271 0.0613 0.0596
Leishmania major casein kinase II, putative 0.0194 0.0335 0.0244
Brugia malayi kettin 0.0137 0.0131 0.0112
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0997 0.3229 0.3197
Schistosoma mansoni tyrosine kinase 0.0181 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0297 0.0708 0.0701
Echinococcus multilocularis cyclin dependent kinase 0.023 0.0465 0.0465
Echinococcus multilocularis neurogenic locus notch protein 4 0.0291 0.0685 0.0685
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus multilocularis Immunoglobulin 0.0541 0.1585 0.1585
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0303 0.0728 0.0711
Giardia lamblia Kinase, CMGC DYRK 0.0269 0.0606 0.1643
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.023 0.0465 0.0459
Echinococcus multilocularis peroxidasin 0.03 0.0719 0.0719
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0163 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.042 0.115 0.115
Toxoplasma gondii AGC kinase 0.055 0.1619 0.158
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus NCK adaptor protein 0.0118 0.0064 0.0064
Loa Loa (eye worm) gastrulation defective protein 1 0.1082 0.3534 0.353
Onchocerca volvulus 0.0265 0.0591 0.2261
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0219 0.0425 0.0335
Echinococcus granulosus growth factor receptor bound protein 2 0.012 0.007 0.007
Entamoeba histolytica serine/threonine protein kinase, putative 0.0151 0.0182 0.066
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0265 0.0591 0.0547
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0267 0.06 0.184
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3165
Brugia malayi hypothetical protein 0.0126 0.0092 0.0073
Plasmodium falciparum apical sushi protein 0.0537 0.1571 0.1532
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0465 0.1423
Schistosoma mansoni g1/s-specific cyclin C 0.1709 0.5793 0.5793
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis death associated protein kinase 1 0.0854 0.2712 0.2712
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0265 0.0591 0.0547
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0236 0.0489 0.0483
Trichomonas vaginalis STE family protein kinase 0.0124 0.0086 0.0246
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Loa Loa (eye worm) AGC/PKN protein kinase 0.0562 0.1661 0.1655
Entamoeba histolytica protein kinase, putative 0.0161 0.0217 0.0785
Brugia malayi Immunoglobulin domain containing protein 0.0163 0.0224 0.0206
Brugia malayi Immunoglobulin I-set domain containing protein 0.1369 0.457 0.456
Loa Loa (eye worm) hypothetical protein 0.0558 0.1648 0.1642
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.0518 0.1586
Brugia malayi Temporarily assigned gene name protein 59 0.0216 0.0415 0.0397
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus multilocularis tyrosine protein kinase Fyn 0.024 0.0501 0.0501
Echinococcus granulosus tyrosine protein kinase Lyn 0.0358 0.0928 0.0928
Loa Loa (eye worm) hypothetical protein 0.0357 0.0925 0.0918
Brugia malayi Protein kinase domain containing protein 0.0388 0.1036 0.1019
Brugia malayi Protein kinase domain containing protein 0.0331 0.083 0.0813
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0865 0.2754 0.274
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0137 0.0133 0.0133
Schistosoma mansoni glutamate synthase 0.0265 0.0591 0.0591
Echinococcus multilocularis insulin growth factor binding 0.0137 0.0131 0.0131
Echinococcus granulosus serine/threonine protein kinase 0.0317 0.0781 0.0781
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0308 0.0746 0.0659
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0194 0.0335 0.029
Plasmodium falciparum casein kinase 1 0.021 0.0395 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.1334 0.1334
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0265 0.0591 0.1711
Echinococcus multilocularis Immunoglobulin 0.0163 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0137 0.0131 0.0131
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0381 0.101 0.1004
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0421 0.1153 0.1136
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Giardia lamblia Kinase, CMGC CK2 0.0194 0.0335 0.0781
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0265 0.0591 0.1812
Trichomonas vaginalis AGC family protein kinase 0.0158 0.0205 0.0616
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0157 0.0204 0.0185
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Loa Loa (eye worm) AGC/PKA protein kinase 0.0219 0.0425 0.0418
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0454 0.1274 0.1274
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0955 0.3079 0.3079
Brugia malayi RhoGAP domain containing protein 0.0144 0.0157 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0181 0.0289 0.0289
Echinococcus granulosus titin 0.0137 0.0131 0.0131
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0265 0.0591 0.0547
Leishmania major protein kinase, putative 0.0227 0.0456 0.0366
Loa Loa (eye worm) hypothetical protein 0.0597 0.1788 0.1782
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Schistosoma mansoni cell adhesion molecule 0.0154 0.0194 0.0194
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0681 0.2092 0.2092
Loa Loa (eye worm) hypothetical protein 0.0216 0.0415 0.0409
Brugia malayi Leucine Rich Repeat family protein 0.0137 0.0133 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0708 0.0708
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0263 0.0795
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Onchocerca volvulus 0.0137 0.0131 0.0425
Loa Loa (eye worm) hypothetical protein 0.0216 0.0415 0.0409
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0236 0.0489 0.0471
Loa Loa (eye worm) hypothetical protein 0.0276 0.0632 0.0625
Echinococcus granulosus low density lipoprotein receptor ldl 0.0163 0.0224 0.0224
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0265 0.0591 0.0573
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0867 0.276 0.2755
Brugia malayi Serine/threonine-protein kinase SULU 0.043 0.1185 0.1168
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0427 0.1176 0.1176
Entamoeba histolytica protein kinase, putative 0.0176 0.0272 0.0985
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0219 0.0425 0.0407
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0155 0.0195 0.0195
Brugia malayi Furin-like cysteine rich region family protein 0.0667 0.2038 0.2023
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0236 0.0489 0.0399
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0439 0.122 0.122
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0227 0.0456 0.165
Trichomonas vaginalis apoptosis inducing factor, putative 0.0265 0.0591 0.1812
Brugia malayi Heparan sulfate 0.0163 0.0224 0.0206
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0762 0.2382 0.2382
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0265 0.0591 0.0547
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Echinococcus granulosus tyrosine protein kinase Src42A 0.0179 0.0282 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0236 0.0489 0.0399
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.03 0.0717 0.0711
Echinococcus granulosus neurogenic locus notch protein 0.0291 0.0685 0.0685
Loa Loa (eye worm) AGC/NDR protein kinase 0.0311 0.0759 0.0752
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0573
Echinococcus multilocularis casein kinase I delta 0.021 0.0395 0.0395
Brugia malayi Kinase associated domain 1 family protein 0.0197 0.0347 0.0329
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.0606 0.0606
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.023 0.0465 0.0465
Entamoeba histolytica PH domain containing protein kinase, putative 0.0317 0.0781 0.2829
Schistosoma mansoni neuroglian 0.0317 0.078 0.078
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0265 0.0591 0.1812
Plasmodium falciparum serine/threonine protein kinase, putative 0.0227 0.0456 0.0411
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Treponema pallidum NADH oxidase 0.0997 0.3229 1
Echinococcus multilocularis titin 0.0218 0.0424 0.0424
Loa Loa (eye worm) protein kinase domain-containing protein 0.0412 0.1122 0.1116
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Brugia malayi basement membrane proteoglycan 0.0163 0.0224 0.0206
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Echinococcus multilocularis hemicentin 1 0.03 0.0717 0.0717
Brugia malayi SRC-1 0.0294 0.0698 0.068
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0317 0.078 0.0774
Loa Loa (eye worm) hypothetical protein 0.0821 0.2596 0.2591
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.018 0.0287 0.0287
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0522 0.1519 0.1513
Toxoplasma gondii histone kinase SNF1, putative 0.0151 0.0182 0.0137
Echinococcus multilocularis neurogenic locus protein delta 0.0291 0.0685 0.0685
Entamoeba histolytica protein kinase, putative 0.0269 0.0606 0.2194
Echinococcus multilocularis mitogen activated protein kinase 14 0.0308 0.0746 0.0746
Trypanosoma cruzi trypanothione reductase, putative 0.0997 0.3229 0.3216
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.024 0.0501 0.0501
Echinococcus multilocularis nervana 2 0.0239 0.0498 0.0498
Echinococcus granulosus c-Jun N-terminal kinases 0.0511 0.1478 0.1478
Echinococcus granulosus cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0151 0.0182 0.0164
Onchocerca volvulus Neurogenic locus notch homolog 0.0291 0.0685 0.2636
Schistosoma mansoni serine/threonine protein kinase 0.0628 0.1901 0.1901
Giardia lamblia Kinase, NEK 0.0263 0.0586 0.158
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0227 0.0456 0.165
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0265 0.0591 0.0547
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0219 0.0425 0.0381
Mycobacterium tuberculosis Probable dehydrogenase 0.0265 0.0591 0.0547
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0137 0.0131 0.0131
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Schistosoma mansoni tyrosine kinase 0.0294 0.0698 0.0698
Loa Loa (eye worm) hypothetical protein 0.084 0.2664 0.2659
Trypanosoma cruzi NADH dehydrogenase, putative 0.0265 0.0591 0.0573
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0127 0.0096 0.0003
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0265 0.0591 0.214
Entamoeba histolytica protein kinase domain containing protein 0.0249 0.0534 0.1934
Brugia malayi Protein kinase domain containing protein 0.0174 0.0263 0.0245
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Echinococcus multilocularis dual specificity 0.0236 0.0489 0.0489
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0415 0.0325
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0997 0.3229 0.3197
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0162 0.0221 0.0203
Schistosoma mansoni tyrosine kinase 0.0123 0.0082 0.0082
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Trypanosoma brucei SNF1-related protein kinases, putative 0.0151 0.0182 0.009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0522 0.1519 0.1519
Brugia malayi Immunoglobulin domain containing protein 0.0163 0.0224 0.0206
Brugia malayi notch-like transmembrane receptor 0.0291 0.0685 0.0667
Echinococcus multilocularis notch 0.0291 0.0685 0.0685
Echinococcus multilocularis 0.0137 0.0131 0.0131
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0317 0.078 0.078
Plasmodium falciparum casein kinase 2, alpha subunit 0.0194 0.0335 0.029
Echinococcus multilocularis protein jagged 2 0.0291 0.0685 0.0685
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0269 0.0606 0.0599
Onchocerca volvulus 0.0126 0.0092 0.027
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0161 0.0217 0.0171
Brugia malayi SH2 domain containing protein 0.0126 0.0092 0.0073
Echinococcus multilocularis neural cadherin 0.0291 0.0685 0.0685
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Schistosoma mansoni sulfide quinone reductase 0.0265 0.0591 0.0591
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus multilocularis neuroglian 0.0678 0.2078 0.2078
Echinococcus multilocularis neurogenic locus notch protein 0.0291 0.0685 0.0685
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0265 0.0591 0.0573
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0163 0.0224 0.0224
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0997 0.3229 1
Schistosoma mansoni cell adhesion molecule 0.0721 0.2234 0.2234
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Echinococcus granulosus basement membrane specific heparan sulfate 0.0163 0.0224 0.0224
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3229
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0454 0.1274 0.1274
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.023 0.0465 0.0421
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0265 0.0591 0.214
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.0433 0.0433
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0534 0.1636
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1146 0.3764 0.376
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Echinococcus granulosus tyrosine kinase 0.0126 0.0092 0.0092
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Loa Loa (eye worm) thyroid receptor interactor 0.0197 0.0349 0.0342
Schistosoma mansoni protein kinase 0.0512 0.1482 0.1482
Echinococcus multilocularis protein kinase c iota type 0.0552 0.1627 0.1627
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0997 0.3229 0.3165
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0265 0.0591 0.0502
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0137 0.0131 0.0131
Brugia malayi pregnancy-associated plasma protein-A 0.0537 0.1571 0.1555
Onchocerca volvulus 0.0628 0.1901 0.7491
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3165
Loa Loa (eye worm) hypothetical protein 0.0613 0.1846 0.184
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0294 0.0698 0.0698
Entamoeba histolytica protein kinase domain containing protein 0.0127 0.0093 0.0338
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0158 0.0205 0.0205
Loa Loa (eye worm) hypothetical protein 0.0579 0.1724 0.1719
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0265 0.0591 0.0547
Onchocerca volvulus 0.0537 0.1571 0.6174
Entamoeba histolytica protein kinase domain containing protein 0.0392 0.1049 0.3798
Brugia malayi GCC2 and GCC3 family protein 0.0827 0.2618 0.2604
Entamoeba histolytica protein kinase domain containing protein 0.0156 0.0198 0.0717
Echinococcus granulosus glutamate synthase 0.0265 0.0591 0.0591
Echinococcus granulosus tyrosine protein kinase 0.0295 0.07 0.07
Plasmodium vivax glutathione reductase, putative 0.2877 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Brugia malayi Serotonin receptor 0.0602 0.1807 0.1791
Echinococcus multilocularis cyclin 0.0855 0.2717 0.2717
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0269 0.0606 0.0562
Brugia malayi Immunoglobulin I-set domain containing protein 0.0317 0.078 0.0763
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0157 0.0204 0.0611
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0997 0.3229 0.3165
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0219 0.0425 0.0407
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.1142 0.1142
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Echinococcus multilocularis dual specificity 0.0269 0.0606 0.0606
Brugia malayi Doublecortin family protein 0.0292 0.0688 0.0671
Plasmodium falciparum serine/threonine protein kinase 0.0161 0.0217 0.0171
Onchocerca volvulus 0.0603 0.1811 0.7131
Echinococcus multilocularis rho associated protein kinase 0.0628 0.1901 0.1901
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.028 0.0646 0.0646
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0265 0.0591 0.0584
Echinococcus granulosus cyclin dependent kinase 9 0.0172 0.0256 0.0256
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Loa Loa (eye worm) hypothetical protein 0.0208 0.0388 0.0381
Echinococcus granulosus tyrosine protein kinase shark 0.0333 0.0837 0.0837
Brugia malayi hypothetical protein 0.0163 0.0224 0.0206
Echinococcus multilocularis casein kinase i 0.021 0.0395 0.0395
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0245 0.0519 0.0519
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0227 0.0456 0.0456
Echinococcus granulosus roundabout 2 0.0317 0.078 0.078
Echinococcus multilocularis slit 2 protein 0.0334 0.0839 0.0839
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0245 0.0519 0.0519
Giardia lamblia Kinase, CAMK CAMKL 0.0167 0.024 0.0478
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0613 0.1846 0.184
Echinococcus granulosus casein kinase I delta 0.021 0.0395 0.0395
Echinococcus granulosus tyrosine kinase 0.024 0.0501 0.0501
Trichomonas vaginalis AGC family protein kinase 0.0263 0.0586 0.1797
Schistosoma mansoni tyrosine kinase 0.0294 0.0698 0.0698
Brugia malayi Protein kinase domain containing protein 0.0867 0.276 0.2746
Brugia malayi Cadherin domain containing protein 0.0291 0.0685 0.0667
Trichomonas vaginalis AGC family protein kinase 0.0346 0.0883 0.2718
Brugia malayi cyclin-dependent kinase 9 0.0156 0.0198 0.018
Entamoeba histolytica protein kinase, putative 0.0161 0.0217 0.0785
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0997 0.3229 0.3216
Schistosoma mansoni tyrosine kinase 0.0386 0.1029 0.1029
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0239 0.0498 0.0498
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0732 0.2275 0.2261
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0265 0.0591 0.0591
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0294 0.0698 0.0698
Echinococcus granulosus dual specificity 0.0269 0.0606 0.0606
Echinococcus granulosus protein kinase C gamma type 0.039 0.1043 0.1043
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0448 0.1252 0.1252
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0158 0.0205 0.0199
Plasmodium falciparum calcium-dependent protein kinase 3 0.0195 0.034 0.0295
Brugia malayi protein unc-22 0.0218 0.0424 0.0406
Trypanosoma cruzi casein kinase, delta isoform, putative 0.021 0.0395 0.0377
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0194 0.0187
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0522 0.1519 0.1519
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0997 0.3229 0.3165
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0439 0.122 0.122
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Entamoeba histolytica protein kinase, putative 0.0139 0.0139 0.0503
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0127 0.0093 0.0075
Echinococcus granulosus casein kinase I alpha 0.021 0.0395 0.0395
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.023 0.0465 0.0375
Echinococcus multilocularis thioredoxin glutathione reductase 0.2877 1 1
Echinococcus granulosus cyclin dependent kinase 1 0.023 0.0465 0.0465
Echinococcus granulosus neurogenic locus protein delta 0.0291 0.0685 0.0685
Schistosoma mansoni growth factor receptor-bound protein 0.0118 0.0064 0.0064
Schistosoma mansoni septate junction protein 0.03 0.0717 0.0717
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0596 0.1784 0.1784
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Loa Loa (eye worm) hypothetical protein 0.0202 0.0364 0.0357
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0146 0.0165 0.0146
Loa Loa (eye worm) hypothetical protein 0.0541 0.1585 0.1579
Toxoplasma gondii thioredoxin reductase 0.2877 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0233 0.0478 0.173
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0164 0.0228 0.0209
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Brugia malayi Protein kinase domain containing protein 0.0161 0.0217 0.0198
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0162 0.0221 0.0203
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0249 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Leishmania major hypothetical protein, conserved 0.0127 0.0096 0.0003
Leishmania major protein kinase, putative 0.0297 0.0708 0.062
Mycobacterium ulcerans hypothetical protein 0.0265 0.0591 0.1711
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Giardia lamblia Kinase, STE STE20 0.0166 0.0237 0.0468
Loa Loa (eye worm) AUR protein kinase 0.0227 0.0456 0.0449
Entamoeba histolytica protein kinase, putative 0.0197 0.0349 0.1264
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0265 0.0591 0.0547
Loa Loa (eye worm) hypothetical protein 0.0827 0.2618 0.2613
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0195 0.034 0.0295
Giardia lamblia Kinase, CDC7 0.0174 0.0263 0.0552
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0126 0.009 0.0044
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0839 0.2658 0.2658
Brugia malayi Stress-activated protein kinase jnk-1 0.0511 0.1478 0.1462
Entamoeba histolytica p21-activated kinase 0.0181 0.029 0.1049
Schistosoma mansoni cell adhesion molecule 0.03 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Loa Loa (eye worm) glutathione reductase 0.2877 1 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0219 0.0425 0.0407
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.018 0.0287 0.028
Echinococcus granulosus contactin 0.0317 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0448 0.1252 0.1246
Brugia malayi Protein kinase domain containing protein 0.0412 0.1122 0.1106
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0249 0.0534 0.0527
Schistosoma mansoni serine/threonine protein kinase 0.0471 0.1334 0.1334
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0205 0.0205
Brugia malayi Prion-like- 0.0137 0.0131 0.0112
Trypanosoma cruzi trypanothione reductase, putative 0.2877 1 1
Echinococcus granulosus serine:threonine kinase SAD 1 0.0151 0.0182 0.0182
Trichomonas vaginalis glutamate synthase, putative 0.0265 0.0591 0.1812
Echinococcus multilocularis cyclin dependent kinase 5 0.023 0.0465 0.0465
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0265 0.0591 0.1711
Echinococcus multilocularis activin receptor type 0.0127 0.0093 0.0093
Entamoeba histolytica protein kinase domain containing protein 0.0194 0.0335 0.1214
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0265 0.0591 0.0547
Plasmodium falciparum protein kinase 5 0.023 0.0465 0.0421
Plasmodium falciparum serine/threonine protein kinase KIN 0.0151 0.0182 0.0137
Schistosoma mansoni tyrosine kinase 0.0269 0.0608 0.0608
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0157 0.0204 0.0112
Trichomonas vaginalis AGC family protein kinase 0.0331 0.083 0.2554
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0163 0.0224 0.0224
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Echinococcus granulosus c src tyrosine kinase 0.0181 0.0289 0.0289
Echinococcus granulosus rho-associated protein kinase 1 0.0628 0.1901 0.1901
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Schistosoma mansoni protein kinase 0.0194 0.0335 0.0335
Onchocerca volvulus Serine\/threonine kinase homolog 0.0317 0.078 0.3018
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0644 0.1956 0.1941
Echinococcus granulosus protein jagged 2 0.0291 0.0685 0.0685
Schistosoma mansoni tyrosine kinase 0.0465 0.1312 0.1312
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0249 0.0534 0.0516
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0511 0.1478 0.1478
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0263 0.0586 0.0542
Loa Loa (eye worm) hypothetical protein 0.0195 0.034 0.0334
Toxoplasma gondii EGF family domain-containing protein 0.0291 0.0685 0.0641
Trypanosoma cruzi aurora B kinase, putative 0.0227 0.0456 0.0438
Loa Loa (eye worm) hypothetical protein 0.0357 0.0923 0.0916
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.03 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni titin 0.03 0.0717 0.0717
Loa Loa (eye worm) casein kinase 0.0348 0.0892 0.0886
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.03 0.0717 0.0711
Brugia malayi protein kinase C II. 0.0394 0.1058 0.1042
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0221 0.0433 0.0426
Trichomonas vaginalis STE family protein kinase 0.0164 0.0228 0.0685
Schistosoma mansoni serine/threonine kinase 0.0311 0.0759 0.0759
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.03 0.0717 0.0717
Loa Loa (eye worm) hypothetical protein 0.0197 0.0347 0.034
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Schistosoma mansoni protein kinase 0.0124 0.0086 0.0086
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0163 0.0224 0.0224
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0265 0.0591 0.0502
Echinococcus granulosus cyclin 0.0855 0.2717 0.2717
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Brugia malayi Protein kinase domain containing protein 0.0578 0.1721 0.1705
Giardia lamblia Kinase, CMGC CLK 0.0297 0.0708 0.1968
Echinococcus granulosus mitogen activated protein kinase 14 0.0308 0.0746 0.0746
Brugia malayi Immunoglobulin I-set domain containing protein 0.0487 0.1392 0.1376
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus multilocularis cyclin dependent kinase 1 0.023 0.0465 0.0465
Giardia lamblia High cysteine protein 0.0291 0.0685 0.1895
Onchocerca volvulus 0.0137 0.0131 0.0425
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.028 0.0646 0.0646
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0249 0.0534 0.0534
Echinococcus multilocularis roundabout 2 0.0317 0.078 0.078
Echinococcus multilocularis fibroblast growth factor receptor 4 0.035 0.0899 0.0899
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0161 0.0217 0.021
Schistosoma mansoni tyrosine kinase 0.0465 0.1312 0.1312
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0162 0.0221 0.0214
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Onchocerca volvulus 0.0174 0.0263 0.0953
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Brugia malayi hypothetical protein 0.043 0.1185 0.1168
Echinococcus granulosus netrin receptor unc 5 0.0219 0.0425 0.0425
Onchocerca volvulus 0.0137 0.0131 0.0425
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0265 0.0591 0.0591
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0997 0.3229 0.3197
Brugia malayi Cyclin C 0.1709 0.5793 0.5785
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0997 0.3229 0.3216
Echinococcus multilocularis protein jagged 1 0.0291 0.0685 0.0685
Echinococcus granulosus serine:threonine protein kinase N2 0.0562 0.1661 0.1661
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0263 0.0795
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus multilocularis C type lectin domian containing protein 0.0537 0.1571 0.1571
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0297 0.0708 0.069
Brugia malayi Cadherin domain containing protein 0.0291 0.0685 0.0667
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0502
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0161 0.0217 0.0125
Entamoeba histolytica protein kinase, putative 0.0158 0.0205 0.0744
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0997 0.3229 1
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0265 0.0591 0.1812
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus granulosus N chimaerin 0.0144 0.0157 0.0157
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.0433 0.0433
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0118 0.0064 0.0064
Echinococcus granulosus mitogen activated protein kinase 3 0.0162 0.0221 0.0221
Plasmodium vivax protein kinase Crk2 0.023 0.0465 0.0421
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0265 0.0591 0.0502
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0137 0.0131 0.0112
Toxoplasma gondii AGC kinase 0.0219 0.0425 0.0381
Schistosoma mansoni serine/threonine protein kinase 0.0562 0.1661 0.1661
Leishmania major casein kinase, putative 0.021 0.0395 0.0304
Echinococcus granulosus tyrosine protein kinase Srms 0.0521 0.1514 0.1514
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0294 0.0698 0.0698
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0127 0.0097 0.035
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0265 0.0591 0.214
Trypanosoma cruzi hypothetical protein, conserved 0.0265 0.0591 0.0573
Loa Loa (eye worm) hypothetical protein 0.0334 0.0839 0.0833
Brugia malayi Protein kinase domain containing protein 0.0373 0.098 0.0963
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0297 0.0708 0.062
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0245 0.0519 0.0501
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0154 0.0154
Brugia malayi Myb-like DNA-binding domain containing protein 0.0137 0.0131 0.0112
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0311 0.0759 0.0759
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0388 0.1035 0.1035
Onchocerca volvulus 0.0137 0.0131 0.0425
Loa Loa (eye worm) hypothetical protein 0.0126 0.0092 0.0085
Echinococcus granulosus protein jagged 1 0.0291 0.0685 0.0685
Echinococcus granulosus protein jagged 2 0.0291 0.0685 0.0685
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0239 0.0498 0.0498
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.018 0.0285 0.0278
Schistosoma mansoni roundabout 0.03 0.0717 0.0717
Echinococcus granulosus casein kinase ii subunit alpha 0.0194 0.0335 0.0335
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0519 0.0519
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0227 0.0456 0.165
Schistosoma mansoni septate junction protein 0.0163 0.0224 0.0224
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0326 0.0813 0.0813
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0127 0.0093 0.0047
Loa Loa (eye worm) TK/FAK protein kinase 0.0559 0.165 0.1644
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Loa Loa (eye worm) hypothetical protein 0.0521 0.1515 0.1509
Entamoeba histolytica protein kinase, putative 0.0195 0.034 0.1232
Trypanosoma brucei cdc2-related kinase 3 0.023 0.0465 0.0375
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Loa Loa (eye worm) hypothetical protein 0.0892 0.2849 0.2844
Echinococcus multilocularis casein kinase I alpha 0.021 0.0395 0.0395
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0361 0.0937 0.0937
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus granulosus c4b binding protein beta chain 0.0537 0.1571 0.1571
Loa Loa (eye worm) hypothetical protein 0.0221 0.0433 0.0426
Schistosoma mansoni kinase 0.0558 0.1648 0.1648
Echinococcus granulosus peroxidasin 0.03 0.0719 0.0719
Leishmania major trypanothione reductase 0.2877 1 1
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0291 0.0685 0.0685
Echinococcus granulosus expressed protein 0.0161 0.0217 0.0217
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0681 0.2092 0.2087
Schistosoma mansoni titin 0.0154 0.0194 0.0194
Echinococcus granulosus dual specificity protein kinase clk2 0.0297 0.0708 0.0708
Echinococcus granulosus tyrosine protein kinase HCK 0.0176 0.0272 0.0272
Toxoplasma gondii CMGC kinase, CK2 family 0.0194 0.0335 0.029
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0126 0.0092 0.0092
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0218 0.0424 0.0417
Echinococcus granulosus titin 0.0218 0.0424 0.0424
Entamoeba histolytica protein kinase, putative 0.0124 0.0086 0.0312
Schistosoma mansoni hemicentin 0.0154 0.0194 0.0194
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0269 0.0606 0.0517
Echinococcus granulosus CDC7 cell division cycle 7 0.0174 0.0263 0.0263
Onchocerca volvulus 0.0124 0.0083 0.0235
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.023 0.0465 0.0375
Schistosoma mansoni protein kinase 0.0166 0.0237 0.0237
Schistosoma mansoni cell polarity protein 0.0291 0.0685 0.0685
Trypanosoma brucei NADH dehydrogenase 0.0265 0.0591 0.0502
Loa Loa (eye worm) AGC/PKA protein kinase 0.0219 0.0425 0.0418
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Echinococcus granulosus cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Echinococcus granulosus leucine rich repeat containing protein 4 0.0137 0.0131 0.0131
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Brugia malayi Protein kinase domain 0.0166 0.0237 0.0219
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0265 0.0591 0.0591
Echinococcus granulosus neuroglian 0.0678 0.2078 0.2078
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0681 0.2092 0.2077
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) TK protein kinase 0.024 0.0501 0.0494
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0194 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Giardia lamblia Kinase, STE STE20 0.0164 0.0228 0.0438
Brugia malayi Protein kinase domain containing protein 0.0419 0.1148 0.1132
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0265 0.0591 0.0547
Trichomonas vaginalis AGC family protein kinase 0.0158 0.0205 0.0616
Brugia malayi probable protein kinase 0.0512 0.1482 0.1466
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0419 0.1148 0.1142
Plasmodium vivax glycogen synthase kinase 3, putative 0.0249 0.0534 0.049
Schistosoma mansoni tyrosine kinase 0.0578 0.1721 0.1721
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.055 0.1619 0.1613
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0465 0.0465
Echinococcus multilocularis serine:threonine protein kinase 3 0.0496 0.1426 0.1426
Schistosoma mansoni serine/threonine protein kinase 0.0762 0.2382 0.2382
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0157 0.0204 0.0204
Giardia lamblia Kinase, NEK 0.0263 0.0586 0.158
Toxoplasma gondii AGC kinase 0.0219 0.0425 0.0381
Plasmodium falciparum glutathione reductase 0.2877 1 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0297 0.0708 0.069
Echinococcus granulosus epidermal growth factor receptor 0.0465 0.1312 0.1312
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni protein kinase 0.0296 0.0704 0.0704
Brugia malayi Prion-like- 0.0137 0.0131 0.0112
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0195 0.034 0.0295
Schistosoma mansoni glutamate synthase 0.0265 0.0591 0.0591
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0311 0.0759 0.0759
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis transfer RNA-Phe 0.0154 0.0194 0.0194
Leishmania major protein kinase A catalytic subunit isoform 2 0.0219 0.0425 0.0335
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0265 0.0591 0.1711
Schistosoma mansoni atypical protein kinase C 0.0564 0.1669 0.1669
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0496 0.1426 0.142
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0162 0.0221 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0019 0.0019
Trypanosoma cruzi polo-like protein kinase, putative 0.0522 0.1519 0.1503
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0265 0.0591 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0265 0.0591 0.0591
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0839 0.2658 0.2658
Entamoeba histolytica hypothetical protein 0.0368 0.0963 0.349
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0317 0.0781 0.0764
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0163 0.0224 0.0224
Entamoeba histolytica serine/threonine protein kinase, putative 0.0522 0.1519 0.5503
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.2877 1 1
Brugia malayi protein kinase C3,putative 0.0305 0.0736 0.0718
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0395 0.1203
Loa Loa (eye worm) TK protein kinase 0.0295 0.07 0.0693
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0143 0.0153 0.0146
Echinococcus granulosus neurogenic locus notch protein 0.0291 0.0685 0.0685
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0166 0.0237 0.0237
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0317 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0392 0.1049 0.1049
Giardia lamblia Kinase, AGC PKA 0.0303 0.0728 0.2034
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0357 0.0925 0.0918
Entamoeba histolytica casein kinase, putative 0.021 0.0395 0.1429
Schistosoma mansoni vav2 0.0159 0.021 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0019 0.0019
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0223 0.0439 0.0439
Loa Loa (eye worm) TK/FER protein kinase 0.042 0.115 0.1144
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trichomonas vaginalis AGC family protein kinase 0.0327 0.0816 0.2513
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0157 0.0202 0.0157
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Trypanosoma cruzi NADH dehydrogenase, putative 0.0265 0.0591 0.0573
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0265 0.0591 0.1711
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0326 0.0813 0.0813
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0249 0.0534 0.0534
Echinococcus multilocularis serine threonine protein kinase 0.039 0.1043 0.1043
Schistosoma mansoni protein kinase 0.0427 0.1176 0.1176
Giardia lamblia Glutamate synthase 0.0265 0.0591 0.1596
Onchocerca volvulus 0.0357 0.0923 0.3586
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Plasmodium vivax serine/threonine protein kinase, putative 0.0161 0.0217 0.0171
Echinococcus multilocularis expressed protein 0.0161 0.0217 0.0217
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0137 0.0131 0.0131
Echinococcus multilocularis fat cadherin tumor suppressor 0.0291 0.0685 0.0685
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0681 0.2092 0.8254
Leishmania major NADH dehydrogenase, putative 0.0265 0.0591 0.0502
Echinococcus granulosus insulin receptor 0.0578 0.1721 0.1721
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0265 0.0591 0.0547
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0163 0.0224 0.0224
Loa Loa (eye worm) TK protein kinase 0.0176 0.0272 0.0265
Giardia lamblia Kinase, CMGC CDK 0.023 0.0465 0.1196
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0294 0.0698 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0291 0.0685 0.0667
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0107 0.0024 0.0017
Brugia malayi Protein kinase domain containing protein 0.1146 0.3764 0.3753
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0265 0.0591 0.0547
Entamoeba histolytica casein kinase, putative 0.0194 0.0335 0.1214
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0265 0.0591 0.1596
Schistosoma mansoni serine/threonine-protein kinase 0.0317 0.0781 0.0781
Brugia malayi Calcium binding EGF domain containing protein 0.0291 0.0685 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.1274 0.1274
Echinococcus granulosus protein tyrosine kinase 0.0553 0.1629 0.1629
Onchocerca volvulus 0.0291 0.0685 0.2636
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi Protein kinase domain containing protein 0.0681 0.2092 0.2077
Echinococcus granulosus nephrin 0.0154 0.0194 0.0194
Loa Loa (eye worm) AUR protein kinase 0.0227 0.0456 0.0449
Loa Loa (eye worm) projectin 0.0154 0.0194 0.0187
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0294 0.0698 0.0698
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.034 0.034
Trypanosoma brucei hypothetical protein, conserved 0.0265 0.0591 0.0502
Echinococcus multilocularis tyrosine protein kinase Srms 0.024 0.0501 0.0501
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0265 0.0591 0.1711
Echinococcus granulosus nervana 2 0.0239 0.0498 0.0498
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0394 0.1058 0.1052
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0171 0.0254 0.0765
Schistosoma mansoni tyrosine kinase 0.0402 0.1087 0.1087
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0265 0.0591 0.214
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0709 0.2191 0.2191
Brugia malayi Protein kinase domain containing protein 0.182 0.6194 0.6187
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Mycobacterium tuberculosis Probable reductase 0.0265 0.0591 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0297 0.0708 0.2175
Schistosoma mansoni ste20-related kinase 0.0397 0.1066 0.1066
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0303 0.0728 0.0728
Echinococcus granulosus tyrosine protein kinase Blk 0.024 0.0501 0.0501
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Mycobacterium ulcerans monoxygenase 0.0265 0.0591 0.1711
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0373 0.098 0.0974
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0151 0.0182 0.009
Onchocerca volvulus 0.0126 0.0092 0.027
Schistosoma mansoni peroxidasin 0.0163 0.0226 0.0226
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0265 0.0591 0.0591
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0219 0.0425 0.0407
Loa Loa (eye worm) hypothetical protein 0.0216 0.0415 0.0409
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0297 0.0708 0.0664
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0249 0.0534 0.049
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0162 0.0221 0.0203
Loa Loa (eye worm) TK/ALK protein kinase 0.0292 0.0688 0.0682
Brugia malayi MAP kinase sur-1 0.0162 0.0221 0.0203
Entamoeba histolytica cell division protein kinase 2, putative 0.023 0.0465 0.1685
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni kinase 0.0156 0.0198 0.0198
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0427 0.1176 0.1176
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0265 0.0591 0.0547
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Echinococcus multilocularis myosin iiia 0.0164 0.0228 0.0228
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0522 0.1519 0.1439
Schistosoma mansoni cell adhesion molecule 0.0163 0.0224 0.0224
Echinococcus granulosus aurora kinase A 0.0227 0.0456 0.0456
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0195 0.034 0.0334
Echinococcus multilocularis cyclin dependent kinase 1 0.023 0.0465 0.0465
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Entamoeba histolytica protein kinase, putative 0.0311 0.0759 0.2747
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Onchocerca volvulus 0.0174 0.0263 0.0953
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0537 0.1571 0.1565
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0227 0.0456 0.0411
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.035 0.0899 0.0899
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Plasmodium falciparum thioredoxin reductase 0.2877 1 1
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0361 0.0937 0.0937
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0226 0.0453 0.0435
Echinococcus multilocularis neurogenic locus protein delta 0.0291 0.0685 0.0685
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0269 0.0606 0.0517
Plasmodium falciparum NIMA related kinase 1 0.0263 0.0586 0.0542
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0445 0.124 0.1223
Loa Loa (eye worm) TK/EGFR protein kinase 0.0667 0.2038 0.2033
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0395 0.1203
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0317 0.078 0.078
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0997 0.3229 0.3197
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0219 0.0425 0.0335
Plasmodium vivax unspecified product 0.0194 0.0335 0.029
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0265 0.0591 0.0547
Trichomonas vaginalis AGC family protein kinase 0.0174 0.0263 0.0796
Entamoeba histolytica protein kinase domain containing protein 0.0249 0.0534 0.1934
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0219 0.0425 0.0381
Entamoeba histolytica protein kinase, putative 0.0249 0.0534 0.1934
Trichomonas vaginalis AGC family protein kinase 0.0331 0.083 0.2554
Echinococcus multilocularis glutamate synthase 0.0265 0.0591 0.0591
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0303 0.0728 0.0728
Trichomonas vaginalis AGC family protein kinase 0.0219 0.0425 0.1298
Brugia malayi ephrin receptor 1 precursor 0.0121 0.0073 0.0055
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0265 0.0591 0.1812
Echinococcus multilocularis roundabout 2 0.0317 0.078 0.078
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0127 0.0093 0.0075
Giardia lamblia Kinase, AGC PKA 0.0219 0.0425 0.1067
Echinococcus granulosus serine:threonine protein kinase 3 0.0496 0.1426 0.1426
Brugia malayi Protein kinase domain containing protein 0.0295 0.07 0.0682
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0997 0.3229 0.3197
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Plasmodium falciparum cGMP-dependent protein kinase 0.0162 0.0222 0.0177
Onchocerca volvulus 0.0126 0.0092 0.027
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.043 0.1185 0.1185
Trichomonas vaginalis CAMK family protein kinase 0.0419 0.1148 0.3543
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0489 0.0489
Loa Loa (eye worm) TK/EPH protein kinase 0.022 0.0431 0.0424
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0474 0.1344 0.1338
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Onchocerca volvulus 0.0137 0.0131 0.0425
Brugia malayi Cam kinase protein 1 0.0195 0.034 0.0322
Echinococcus granulosus dual specificity 0.0236 0.0489 0.0489
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.021 0.0395 0.0388
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0241 0.0506 0.0416
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0511 0.1478 0.1478
Onchocerca volvulus 0.0126 0.0092 0.027
Toxoplasma gondii aurora kinase 0.0227 0.0456 0.0411
Loa Loa (eye worm) TK/ROR protein kinase 0.02 0.0356 0.035
Echinococcus multilocularis epidermal growth factor receptor 0.0465 0.1312 0.1312
Echinococcus granulosus protein kinase c iota type 0.0552 0.1627 0.1627
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0194 0.0335 0.0328
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0162 0.0221 0.0176
Loa Loa (eye worm) hypothetical protein 0.0276 0.0632 0.0625
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0681 0.2092 0.2087
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0223 0.0439 0.0439
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus multilocularis cyclin dependent kinase 9 0.0172 0.0256 0.0256
Entamoeba histolytica protein kinase domain containing protein 0.0269 0.0606 0.2194
Loa Loa (eye worm) TK/FER protein kinase 0.0126 0.0092 0.0085
Schistosoma mansoni rap gtpase-activating protein 0.0216 0.0415 0.0415
Echinococcus multilocularis tyrosine protein kinase Blk 0.024 0.0501 0.0501
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0221 0.0665
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.023 0.0465 0.0459
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0265 0.0591 0.1711
Onchocerca volvulus 0.0291 0.0685 0.2636
Loa Loa (eye worm) hypothetical protein 0.03 0.0717 0.0711
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0164 0.0228 0.0824
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0162 0.0221 0.0129
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0195 0.034 0.0322
Giardia lamblia Kinase, PLK 0.0522 0.1519 0.4554
Entamoeba histolytica protein kinase domain containing protein 0.0227 0.0456 0.165
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0263 0.0795
Echinococcus granulosus insulin growth factor binding 0.0137 0.0131 0.0131
Echinococcus multilocularis serine:threonine protein kinase N2 0.0311 0.0759 0.0759
Trichomonas vaginalis CAMK family protein kinase 0.0244 0.0518 0.1586
Echinococcus multilocularis mitogen activated protein kinase 11 0.0308 0.0746 0.0746
Loa Loa (eye worm) hypothetical protein 0.0219 0.0425 0.0418
Echinococcus granulosus activin receptor type 0.0127 0.0093 0.0093
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0265 0.0591 0.1711
Trichomonas vaginalis conserved hypothetical protein 0.0113 0.0046 0.0122
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Echinococcus multilocularis ephrin type A receptor 4 A 0.0186 0.0309 0.0309
Echinococcus granulosus ephrin type A receptor 4 A 0.0186 0.0309 0.0309
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Plasmodium falciparum calcium-dependent protein kinase 2 0.0195 0.034 0.0295
Loa Loa (eye worm) CAMK/PKD protein kinase 0.034 0.0862 0.0855
Brugia malayi Prion-like- 0.0137 0.0131 0.0112
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Trypanosoma brucei rac serine-threonine kinase, putative 0.0565 0.1672 0.1593
Schistosoma mansoni sulfide quinone reductase 0.0265 0.0591 0.0591
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0511 0.1478 0.1472
Brugia malayi Protein kinase c protein 2 0.0224 0.0444 0.0426
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Plasmodium falciparum thioredoxin reductase 0.0997 0.3229 0.3197
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3165
Loa Loa (eye worm) AGC/AKT protein kinase 0.0565 0.1672 0.1666
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0541 0.1585 0.1585
Loa Loa (eye worm) hypothetical protein 0.0173 0.0259 0.0252
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0151 0.0182 0.0164
Entamoeba histolytica protein kinase, putative 0.0565 0.1672 0.6055
Echinococcus multilocularis protein tyrosine kinase 0.0553 0.1629 0.1629
Echinococcus multilocularis PAK box P21 Rho binding 0.0124 0.0086 0.0086
Schistosoma mansoni cell adhesion molecule 0.0137 0.0131 0.0131
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3216
Echinococcus granulosus calcium dependent protein kinase 0.0131 0.011 0.011
Onchocerca volvulus Serine\/threonine kinase homolog 0.0522 0.1519 0.5967
Trypanosoma brucei protein kinase, putative 0.0178 0.0279 0.0187
Trypanosoma brucei polo-like protein kinase 0.0522 0.1519 0.1439
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus granulosus Immunoglobulin subtype 0.0163 0.0224 0.0224
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0997 0.3229 0.3216
Echinococcus multilocularis protein jagged 1 0.0291 0.0685 0.0685
Brugia malayi hypothetical protein 0.0216 0.0415 0.0397
Schistosoma mansoni slit 0.0137 0.0133 0.0133
Giardia lamblia Aurora kinase 0.0227 0.0456 0.1165
Echinococcus multilocularis Immunoglobulin 0.0541 0.1585 0.1585
Echinococcus multilocularis c4b binding protein beta chain 0.0537 0.1571 0.1571
Schistosoma mansoni septate junction protein 0.03 0.0717 0.0717
Echinococcus granulosus hemicentin 1 0.03 0.0717 0.0717
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0997 0.3229 0.3197
Onchocerca volvulus Putative titin 0.0137 0.0131 0.0425
Schistosoma mansoni protein kinase 0.0227 0.0456 0.0456
Loa Loa (eye worm) notch protein 0.0291 0.0685 0.0678
Schistosoma mansoni protein kinase 0.0709 0.2191 0.2191
Echinococcus multilocularis protein kinase shaggy 0.0249 0.0534 0.0534
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Echinococcus multilocularis mitogen activated protein kinase 14 0.0308 0.0746 0.0746
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Loa Loa (eye worm) TK protein kinase 0.0487 0.1392 0.1386
Echinococcus multilocularis tyrosine protein kinase HCK 0.0176 0.0272 0.0272
Echinococcus multilocularis raf serine:threonine protein kinase 0.0143 0.0154 0.0154
Entamoeba histolytica PH domain containing protein kinase, putative 0.0233 0.0478 0.173
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Trypanosoma brucei aurora B kinase 0.0227 0.0456 0.0366
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0703 0.2171 0.2171
Brugia malayi Protein kinase domain containing protein 0.0565 0.1672 0.1656
Brugia malayi serine/threonine-protein kinase plk-2 0.0522 0.1519 0.1503
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Loa Loa (eye worm) one IG domain family member 0.0137 0.0131 0.0124
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0284 0.0662 0.2034
Echinococcus granulosus neurogenic locus notch protein 4 0.0291 0.0685 0.0685
Plasmodium vivax apical sushi protein, putative 0.0537 0.1571 0.1532
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0137 0.0131 0.0124
Echinococcus multilocularis casein kinase I alpha 0.021 0.0395 0.0395
Trypanosoma cruzi polo-like protein kinase, putative 0.0522 0.1519 0.1503
Schistosoma mansoni protein kinase 0.0127 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0265 0.0591 0.0584
Echinococcus multilocularis mitogen activated protein kinase 11 0.0308 0.0746 0.0746
Echinococcus multilocularis mitogen activated protein kinase 3 0.0162 0.0221 0.0221
Loa Loa (eye worm) disorganized muscle protein 1 0.0137 0.0131 0.0124
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0265 0.0591 0.0591
Echinococcus granulosus cGMP dependent protein kinase 0.0162 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Schistosoma mansoni tyrosine kinase 0.0578 0.1721 0.1721
Trypanosoma brucei casein kinase I, isoform 2 0.021 0.0395 0.0304
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0308 0.0746 0.0739
Giardia lamblia Kinase, CK1 Casein kinase 0.021 0.0395 0.0971
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0392 0.1049 0.1049
Brugia malayi SH2 domain containing protein 0.042 0.115 0.1134
Echinococcus granulosus tyrosine protein kinase Fps85D 0.042 0.115 0.115
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0265 0.0591 0.0502
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0126 0.009 0.0262
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0292 0.0688 0.0682
Leishmania major protein kinase, putative 0.0164 0.0228 0.0135
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0269 0.0606 0.0588
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus granulosus titin 0.0137 0.0131 0.0131
Brugia malayi serine/threonine-protein kinase 6 0.0227 0.0456 0.0438
Echinococcus granulosus Vam6:Vps39 protein 0.0216 0.0415 0.0415
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0195 0.034 0.0249
Echinococcus multilocularis roundabout 2 0.0858 0.2727 0.2727
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Schistosoma mansoni serine/threonine protein kinase 0.0922 0.2958 0.2958
Echinococcus multilocularis conserved hypothetical protein 0.0833 0.2639 0.2639
Echinococcus multilocularis hemicentin 1 0.03 0.0717 0.0717
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0126 0.009 0.0137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0137 0.0131 0.0131
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0762 0.2382 0.2377
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Echinococcus granulosus casein kinase I alpha 0.021 0.0395 0.0395
Echinococcus granulosus nervana 2 0.0239 0.0498 0.0498
Echinococcus granulosus titin 0.0137 0.0131 0.0131
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0163 0.0224 0.0217
Mycobacterium ulcerans dehydrogenase 0.0265 0.0591 0.1711
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0263 0.0586 0.0542
Leishmania major hypothetical protein, conserved 0.0265 0.0591 0.0502
Loa Loa (eye worm) AGC/PKG protein kinase 0.0162 0.0222 0.0216
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0303 0.0728 0.0685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0195 0.034 0.1035
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0732 0.2275 0.2261
Echinococcus multilocularis tyrosine protein kinase shark 0.0333 0.0837 0.0837
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0195 0.034 0.0295
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Schistosoma mansoni cell adhesion molecule 0.0154 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Entamoeba histolytica protein kinase, putative 0.0139 0.0139 0.0503
Schistosoma mansoni nephrin related 0.0137 0.0131 0.0131
Brugia malayi Animal haem peroxidase family protein 0.0137 0.0131 0.0112
Echinococcus multilocularis expressed conserved protein 0.0162 0.0222 0.0222
Toxoplasma gondii selenide, water dikinase 0.0265 0.0591 0.0547
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0249 0.0534 0.0445
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Onchocerca volvulus 0.0537 0.1571 0.6174
Echinococcus granulosus tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0106 0.0019 0.0012
Onchocerca volvulus 0.021 0.0395 0.1478
Leishmania major hypothetical protein, conserved 0.0265 0.0591 0.0502
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0157 0.0204 0.0204
Echinococcus multilocularis titin 0.0137 0.0131 0.0131
Schistosoma mansoni slit 0.0291 0.0687 0.0687
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Loa Loa (eye worm) hypothetical protein 0.0317 0.078 0.0774
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0855 0.2717 0.2717
Brugia malayi STE20-like kinase MST 0.0496 0.1426 0.141
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Giardia lamblia Kinase, CMGC MAPK 0.0162 0.0221 0.0418
Schistosoma mansoni cell adhesion molecule 0.0317 0.078 0.078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0317 0.078 0.0763
Loa Loa (eye worm) hypothetical protein 0.0541 0.1585 0.1579
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Echinococcus multilocularis growth factor receptor bound protein 2 0.0118 0.0064 0.0064
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0249 0.0534 0.0527
Brugia malayi intracellular kinase 0.0249 0.0534 0.0516
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Echinococcus granulosus NDR protein kinase 0.0311 0.0759 0.0759
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0144 0.0157 0.0157
Echinococcus granulosus raf serine:threonine protein kinase 0.0143 0.0154 0.0154
Brugia malayi Protein kinase domain containing protein 0.0375 0.0987 0.097
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0997 0.3229 0.3197
Brugia malayi casein kinase 1, delta 0.021 0.0395 0.0377
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0392 0.1049 0.1042
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Echinococcus multilocularis fibropellin Ia 0.0291 0.0685 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Echinococcus granulosus neural cadherin 0.0291 0.0685 0.0685
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0265 0.0591 0.0591
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0997 0.3229 1
Echinococcus multilocularis insulin receptor 0.0578 0.1721 0.1721
Schistosoma mansoni tyrosine kinase 0.0402 0.1087 0.1087
Brugia malayi Protein kinase domain containing protein 0.0613 0.1846 0.183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0558 0.1648 0.1632
Schistosoma mansoni serine/threonine protein kinase 0.0474 0.1344 0.1344
Giardia lamblia Kinase, AGC AKT 0.0226 0.0453 0.1157
Entamoeba histolytica cell division protein kinase 2, putative 0.0246 0.0523 0.1895
Onchocerca volvulus 0.0276 0.0632 0.2424
Brugia malayi Variant SH3 domain containing protein 0.0118 0.0064 0.0045
Schistosoma mansoni protein kinase 0.0839 0.2658 0.2658
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0161 0.0217 0.0198
Loa Loa (eye worm) hypothetical protein 0.0371 0.0976 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0997 0.3229 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0181 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0233 0.0478 0.0471
Schistosoma mansoni serine/threonine protein kinase 0.0311 0.0759 0.0759
Trichomonas vaginalis CMGC family protein kinase 0.0249 0.0534 0.1636
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0297 0.0708 0.069
Onchocerca volvulus 0.0371 0.0976 0.3796
Brugia malayi glutamate synthase 0.0265 0.0591 0.0573
Echinococcus multilocularis epidermal growth factor receptor 0.0667 0.2038 0.2038
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0654 0.1994 0.1988
Brugia malayi Muscle positioning protein 4 0.0291 0.0685 0.0667
Echinococcus granulosus down syndrome cell adhesion 0.0137 0.0131 0.0131
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0361 0.0937 0.0937
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0955 0.3079 0.3079
Plasmodium falciparum calcium-dependent protein kinase 4 0.0195 0.034 0.0295
Onchocerca volvulus 0.0154 0.0194 0.0676
Echinococcus multilocularis casein kinase I delta 0.021 0.0395 0.0395
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0157 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0558 0.1648 0.1642
Echinococcus multilocularis 0.0233 0.0478 0.0478
Brugia malayi Immunoglobulin I-set domain containing protein 0.0154 0.0194 0.0175
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0151 0.0182 0.0175
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.0522 0.1519 0.4695
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0163 0.0224 0.0224
Brugia malayi Cyclin, N-terminal domain containing protein 0.0855 0.2717 0.2703
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3229
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi EGF-like domain containing protein 0.0334 0.0839 0.0822
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0424 0.0424
Echinococcus granulosus roundabout 2 0.0858 0.2727 0.2727
Loa Loa (eye worm) hypothetical protein 0.0558 0.1648 0.1642
Echinococcus granulosus protein jagged 1 0.0291 0.0685 0.0685
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Plasmodium falciparum protein serine/threonine kinase-1 0.0297 0.0708 0.0664
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0311 0.0759 0.0759
Schistosoma mansoni ephrin receptor 0.0186 0.0309 0.0309
Schistosoma mansoni c4b-binding protein beta chain 0.0537 0.1571 0.1571
Loa Loa (eye worm) animal heme peroxidase 0.0137 0.0131 0.0124
Echinococcus multilocularis dual specificity protein kinase clk2 0.0297 0.0708 0.0708
Mycobacterium tuberculosis Conserved hypothetical protein 0.0127 0.0096 0.005
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0106 0.0019 0.0012
Trypanosoma cruzi Protein kinase B 0.0317 0.0781 0.0764
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0164 0.0227 0.0227
Schistosoma mansoni basigin related 0.0163 0.0224 0.0224
Entamoeba histolytica cyclin C, putative 0.0867 0.2761 1
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0265 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0395 0.0395
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Trichomonas vaginalis CAMK family protein kinase 0.0221 0.0433 0.1321
Echinococcus multilocularis NCK adaptor protein 0.012 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0349 0.0895 0.0888
Giardia lamblia NADH oxidase lateral transfer candidate 0.0997 0.3229 1
Mycobacterium ulcerans ferredoxin reductase 0.0265 0.0591 0.1711
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Trichomonas vaginalis glutathione reductase, putative 0.0997 0.3229 1
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0265 0.0591 0.0547
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0151 0.0182 0.009
Brugia malayi Protein kinase domain containing protein 0.0613 0.1846 0.183
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0118 0.0064 0.0057
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0144 0.0157 0.0151
Schistosoma mansoni netrin receptor unc5 0.0163 0.0224 0.0224
Brugia malayi Delta serrate ligand family protein 0.0291 0.0685 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.0311 0.0759 0.0759
Echinococcus granulosus cyclin dependent kinase 0.023 0.0465 0.0465
Echinococcus multilocularis neuroglian 0.0317 0.078 0.078
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.0439 0.1342
Loa Loa (eye worm) hypothetical protein 0.0445 0.124 0.1234
Onchocerca volvulus Peroxidasin homolog 0.0137 0.0131 0.0425
Schistosoma mansoni hypothetical protein 0.0163 0.0224 0.0224
Echinococcus granulosus protein kinase 0.0296 0.0704 0.0704
Schistosoma mansoni serine/threonine protein kinase 0.0493 0.1413 0.1413
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni adapter molecule crk 0.0118 0.0064 0.0064
Trypanosoma cruzi cdc2-related kinase 1 0.023 0.0465 0.0447
Schistosoma mansoni nephrin 0.0695 0.2141 0.2141
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0294 0.0698 0.0698
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.021 0.0395 0.0388
Schistosoma mansoni disulfide oxidoreductase 0.0265 0.0591 0.0591
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0158 0.0205 0.0205
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0361 0.0937 0.0931
Brugia malayi EGF-like domain containing protein 0.0291 0.0685 0.0667
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0195 0.034 0.0295
Echinococcus multilocularis 0.0296 0.0704 0.0704
Echinococcus multilocularis Immunoglobulin 0.0163 0.0224 0.0224
Onchocerca volvulus 0.0249 0.0534 0.2034
Echinococcus granulosus twitchin 0.0741 0.2308 0.2308
Plasmodium falciparum ferrodoxin reductase-like protein 0.0265 0.0591 0.0547
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0224 0.0206
Onchocerca volvulus 0.0291 0.0685 0.2636
Echinococcus granulosus tyrosine protein kinase Src64B 0.0294 0.0698 0.0698
Echinococcus granulosus tyrosine protein kinase Src42A 0.0294 0.0698 0.0698
Plasmodium vivax thioredoxin reductase, putative 0.2877 1 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Echinococcus multilocularis netrin receptor unc 5 0.0219 0.0425 0.0425
Trichomonas vaginalis CMGC family protein kinase 0.0194 0.0335 0.1019
Brugia malayi Variant SH3 domain containing protein 0.0144 0.0157 0.0139
Schistosoma mansoni vam6/vps39 related 0.0216 0.0415 0.0415
Schistosoma mansoni protein kinase 0.0373 0.098 0.098
Loa Loa (eye worm) TK protein kinase 0.0356 0.0922 0.0915
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.043 0.1185 0.1179
Echinococcus multilocularis cyclin dependent kinase 19 0.1146 0.3764 0.3764
Echinococcus multilocularis Immunoglobulin subtype 0.0163 0.0224 0.0224
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0265 0.0591 0.1711
Echinococcus multilocularis casein kinase ii subunit alpha 0.0194 0.0335 0.0335
Echinococcus multilocularis neurogenic locus notch protein 0.0291 0.0685 0.0685
Schistosoma mansoni tyrosine kinase 0.035 0.0899 0.0899
Mycobacterium ulcerans NADH dehydrogenase 0.0265 0.0591 0.1711
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0865 0.2754 0.2754
Onchocerca volvulus 0.0291 0.0685 0.2636
Loa Loa (eye worm) cyclin domain-containing protein 0.0855 0.2717 0.2712
Leishmania major protein kinase A catalytic subunit isoform 1 0.0219 0.0425 0.0335
Giardia lamblia Kinase, CMGC GSK 0.0249 0.0534 0.1414
Onchocerca volvulus 0.0268 0.0604 0.2312
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus Immunoglobulin 0.0163 0.0224 0.0224
Brugia malayi casein kinase I 0.021 0.0395 0.0377
Schistosoma mansoni serine/threonine protein kinase 0.0388 0.1036 0.1036
Loa Loa (eye worm) SRC-1 0.0294 0.0698 0.0691
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0236 0.0489 0.0471
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Trichomonas vaginalis AGC family protein kinase 0.0227 0.0456 0.1393
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0474 0.1344 0.1344
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0265 0.0591 0.0573
Schistosoma mansoni myosin-binding protein-related 0.0154 0.0194 0.0194
Echinococcus granulosus slit 2 protein 0.0334 0.0839 0.0839
Echinococcus granulosus cyclin dependent kinase 5 0.023 0.0465 0.0465
Echinococcus granulosus lachesin 0.03 0.0717 0.0717
Trichomonas vaginalis conserved hypothetical protein 0.0284 0.0662 0.2034
Echinococcus granulosus dual specificity 0.0269 0.0606 0.0606
Echinococcus granulosus mitogen activated protein kinase 11 0.0308 0.0746 0.0746
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0265 0.0591 0.0547
Loa Loa (eye worm) Notch2 0.0291 0.0685 0.0678
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0326 0.0813 0.0813
Schistosoma mansoni protein kinase C mu 0.0421 0.1153 0.1153
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0577 0.0577
Schistosoma mansoni netrin receptor unc5 0.0219 0.0425 0.0425
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Giardia lamblia Kinase, CMGC SRPK 0.0161 0.0217 0.0404
Brugia malayi serine/threonine-protein kinase PAK 7 0.0449 0.1254 0.1237
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0127 0.0096 0.0077
Entamoeba histolytica casein kinase 1, putative 0.021 0.0395 0.1429
Brugia malayi p70 ribosomal S6 kinase beta 0.055 0.1619 0.1603
Onchocerca volvulus 0.0137 0.0133 0.0432
Brugia malayi Protein kinase domain containing protein 0.0317 0.078 0.0763
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0162 0.0221 0.0129
Mycobacterium ulcerans glutamate synthase subunit beta 0.0265 0.0591 0.1711
Loa Loa (eye worm) hypothetical protein 0.0151 0.0182 0.0175
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0265 0.0591 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0454 0.1274 0.1274
Echinococcus multilocularis dual specificity 0.0269 0.0606 0.0606
Entamoeba histolytica protein kinase, putative 0.0227 0.0456 0.165
Echinococcus multilocularis serine:threonine protein kinase N2 0.0562 0.1661 0.1661
Echinococcus granulosus Immunoglobulin 0.0541 0.1585 0.1585
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0195 0.034 0.0295
Entamoeba histolytica protein kinase, putative 0.0227 0.0456 0.165
Schistosoma mansoni notch 0.0291 0.0685 0.0685
Loa Loa (eye worm) CDC7 protein kinase 0.0174 0.0263 0.0256
Onchocerca volvulus Putative cubilin 0.0291 0.0685 0.2636
Onchocerca volvulus Tyrosine kinase homolog 0.0803 0.253 1
Echinococcus multilocularis 0.0185 0.0303 0.0303
Echinococcus granulosus Immunoglobulin 0.0163 0.0224 0.0224
Brugia malayi hypothetical protein 0.0558 0.1648 0.1632
Brugia malayi Protein kinase domain containing protein 0.0297 0.0708 0.069
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0106 0.0019 0.0037
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0644 0.1956 0.195
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.0287 0.0269
Plasmodium falciparum calcium-dependent protein kinase 1 0.0195 0.034 0.0295
Brugia malayi Prion-like- 0.03 0.0717 0.07
Brugia malayi serine/threonine protein kinase 6 0.0227 0.0456 0.0438
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0296 0.0704 0.0698
Echinococcus granulosus cyclin dependent kinase 19 0.1146 0.3764 0.3764
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0415 0.0415
Echinococcus multilocularis tyrosine protein kinase 0.0295 0.07 0.07
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0269 0.0606 0.0588
Entamoeba histolytica protein kinase, putative 0.0127 0.0097 0.035
Echinococcus multilocularis serine:threonine protein kinase 0.0221 0.0433 0.0433
Onchocerca volvulus 0.0123 0.0079 0.0218
Onchocerca volvulus 0.0537 0.1571 0.6174
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Plasmodium vivax tyrosine kinase-like protein, putative 0.0157 0.0202 0.0157
Echinococcus multilocularis serine:threonine protein kinase N2 0.0251 0.054 0.054
Trypanosoma brucei trypanothione reductase 0.2877 1 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0418 0.1142 0.1142
Loa Loa (eye worm) hypothetical protein 0.0541 0.1587 0.1581
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0284 0.0662 0.2034
Echinococcus granulosus protein kinase shaggy 0.0249 0.0534 0.0534
Entamoeba histolytica protein kinase, putative 0.0166 0.0237 0.0859
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0162 0.0221 0.0203
Schistosoma mansoni titin 0.0218 0.0424 0.0424
Brugia malayi Protein kinase domain containing protein 0.012 0.0069 0.005
Schistosoma mansoni purine nucleoside phosphorylase 0.0126 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Schistosoma mansoni growth factor receptor-bound protein 0.012 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0157 0.0205 0.0198
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.023 0.0465 0.0459
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0997 0.3229 0.3229
Trypanosoma cruzi casein kinase, putative 0.021 0.0395 0.0377
Schistosoma mansoni protein kinase 0.021 0.0395 0.0395
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0265 0.0591 0.0547
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0245 0.0519 0.0512
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0195 0.034 0.0295
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0265 0.0591 0.1711
Echinococcus multilocularis cyclin dependent kinase 9 0.0156 0.0198 0.0198
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0163 0.0224 0.0224
Schistosoma mansoni nephrin related 0.0163 0.0224 0.0224
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0219 0.0425 0.0381
Echinococcus granulosus dual specificity 0.0269 0.0606 0.0606
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0126 0.009 0.0258
Echinococcus multilocularis CDC7 cell division cycle 7 0.0174 0.0263 0.0263
Echinococcus granulosus casein kinase I gamma 0.0412 0.1122 0.1122
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0709 0.2191 0.2185
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.0439 0.1342
Echinococcus multilocularis c src tyrosine kinase 0.0181 0.0289 0.0289
Schistosoma mansoni hypothetical protein 0.0216 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0268 0.0604 0.0597
Plasmodium vivax ferrodoxin reductase, putative 0.0265 0.0591 0.0547
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Brugia malayi Immunoglobulin I-set domain containing protein 0.0317 0.078 0.0763
Loa Loa (eye worm) hypothetical protein 0.084 0.2664 0.2659
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Echinococcus granulosus tyrosine protein kinase Fyn 0.0294 0.0698 0.0698
Schistosoma mansoni vesicular amine transporter 0.0541 0.1585 0.1585
Onchocerca volvulus 0.0565 0.1671 0.6573
Schistosoma mansoni protein kinase 0.0427 0.1176 0.1176
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0265 0.0591 0.0591
Echinococcus granulosus casein kinase i 0.021 0.0395 0.0395
Echinococcus granulosus serine threonine protein kinase nrc 0.0303 0.0728 0.0728
Echinococcus multilocularis dual specificity 0.0269 0.0606 0.0606
Schistosoma mansoni serine/threonine protein kinase 0.1146 0.3764 0.3764
Brugia malayi Fibronectin type III domain containing protein 0.0558 0.1648 0.1632
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0502
Brugia malayi Calcium binding EGF domain containing protein 0.0291 0.0685 0.0667
Schistosoma mansoni hypothetical protein 0.0197 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0118 0.0064 0.0057
Echinococcus multilocularis hypothetical protein 0.0197 0.0347 0.0347
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0303 0.0728 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0394 0.1058 0.1058
Loa Loa (eye worm) thioredoxin reductase 0.2877 1 1
Brugia malayi Protein kinase domain containing protein 0.0559 0.165 0.1634
Echinococcus multilocularis down syndrome cell adhesion 0.0137 0.0131 0.0131
Schistosoma mansoni serine/threonine kinase 0.0436 0.1206 0.1206
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1405 0.4697 0.4697
Brugia malayi Fes/CIP4 homology domain containing protein 0.0197 0.0349 0.0331
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0265 0.0591 0.1711
Brugia malayi Hr1 repeat family protein 0.0562 0.1661 0.1645
Brugia malayi hypothetical protein 0.0537 0.1571 0.1555
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0166 0.0237 0.0237
Brugia malayi Immunoglobulin I-set domain containing protein 0.0218 0.0424 0.0406
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0167 0.024 0.0195
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0361 0.0361
Entamoeba histolytica PH domain containing protein kinase, putative 0.0317 0.0781 0.2829
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.028 0.0646 0.0646
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.02 0.0356 0.0356
Echinococcus multilocularis titin 0.0137 0.0131 0.0131
Entamoeba histolytica hypothetical protein 0.0236 0.0489 0.1772
Toxoplasma gondii rhoptry neck protein RON9 0.0537 0.1571 0.1532
Loa Loa (eye worm) hypothetical protein 0.0708 0.2188 0.2182
Brugia malayi Protein kinase domain containing protein 0.0292 0.0689 0.0671
Plasmodium vivax casein kinase 1, putative 0.021 0.0395 0.035
Trichomonas vaginalis STE family protein kinase 0.0166 0.0237 0.0714
Echinococcus multilocularis tyrosine protein kinase otk 0.03 0.0717 0.0717
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0265 0.0591 0.0573
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0265 0.0591 0.214
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0164 0.0228 0.0135
Loa Loa (eye worm) TK/ABL protein kinase 0.0126 0.0092 0.0085
Giardia lamblia Kinase, CMGC CDK 0.023 0.0465 0.1196
Echinococcus granulosus Glutaredoxin protein 5 0.0239 0.0498 0.0498
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0241 0.0504 0.144
Schistosoma mansoni serine/threonine-protein kinase 0.0317 0.0781 0.0781
Onchocerca volvulus 0.0537 0.1571 0.6174
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0182 0.0182
Brugia malayi serine/threonine kinase 12 0.0227 0.0456 0.0438
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Brugia malayi Temporarily assigned gene name protein 59 0.0249 0.0536 0.0518
Trypanosoma cruzi cdc2-related kinase 1 0.023 0.0465 0.0447
Brugia malayi putative serine/threonine kinase SADA gamma 0.0151 0.0182 0.0164
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0265 0.0591 0.1711
Onchocerca volvulus 0.0537 0.1571 0.6174
Schistosoma mansoni protein kinase 0.0166 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Entamoeba histolytica protein kinase , putative 0.0227 0.0456 0.165
Loa Loa (eye worm) hypothetical protein 0.0154 0.0194 0.0187
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0596 0.1784 0.1784
Echinococcus granulosus titin 0.0218 0.0424 0.0424
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus granulosus notch 0.0291 0.0685 0.0685
Schistosoma mansoni laminin gamma-3 chain 0.0291 0.0685 0.0685
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus 0.0154 0.0194 0.0676
Brugia malayi Protein kinase domain containing protein 0.023 0.0465 0.0447
Brugia malayi Immunoglobulin I-set domain containing protein 0.018 0.0285 0.0267
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0195 0.034 0.0334
Brugia malayi Immunoglobulin I-set domain containing protein 0.0137 0.0131 0.0112
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0151 0.0182 0.009
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0855 0.2717 0.2717
Giardia lamblia Kinase, NEK 0.0263 0.0586 0.158
Entamoeba histolytica protein kinase, putative 0.055 0.1619 0.5865
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0144 0.0157 0.0157
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0265 0.0591 0.0591
Trypanosoma brucei Casein kinase II 0.0194 0.0335 0.0244
Onchocerca volvulus 0.0137 0.0131 0.0425
Loa Loa (eye worm) hypothetical protein 0.0166 0.0235 0.0228
Echinococcus multilocularis casein kinase I gamma 0.0412 0.1122 0.1122
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0308 0.0746 0.0659
Entamoeba histolytica protein kinase, putative 0.0236 0.0489 0.1772
Echinococcus granulosus defective proboscis extension response 0.0541 0.1585 0.1585
Entamoeba histolytica protein kinase, putative 0.0236 0.0489 0.1772
Schistosoma mansoni glutamate synthase 0.0265 0.0591 0.0591
Schistosoma mansoni tyrosine kinase 0.0667 0.2038 0.2038
Echinococcus granulosus tyrosine protein kinase ABL1 0.0126 0.0092 0.0092
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0465 0.1312 0.1312
Echinococcus multilocularis tyrosine kinase 0.0126 0.0092 0.0092
Trichomonas vaginalis CK1 family protein kinase 0.021 0.0395 0.1203
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0388 0.1035 0.1035
Echinococcus granulosus serine:threonine protein kinase N2 0.0251 0.054 0.054
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Trichomonas vaginalis glutamate synthase, putative 0.0265 0.0591 0.1812
Echinococcus granulosus mitogen activated protein kinase 0.0162 0.0221 0.0221
Schistosoma mansoni protein kinase 0.0839 0.2658 0.2658
Schistosoma mansoni serine/threonine protein kinase 0.0412 0.1122 0.1122
Schistosoma mansoni serine/threonine protein kinase 0.043 0.1185 0.1185
Echinococcus granulosus hypothetical protein 0.088 0.2807 0.2807
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0317 0.0778 0.0772
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.028 0.0646 0.0646
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.02 0.0356 0.0356
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0265 0.0591 0.0573
Echinococcus granulosus serine:threonine protein kinase 0.0221 0.0433 0.0433
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Brugia malayi basement membrane proteoglycan precursor 0.0163 0.0224 0.0206
Entamoeba histolytica disulphide oxidoreductase, putative 0.0265 0.0591 0.214
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0157 0.0204 0.0611
Onchocerca volvulus 0.0537 0.1571 0.6174
Trypanosoma brucei protein kinase, putative 0.0249 0.0534 0.0445
Schistosoma mansoni hypothetical protein 0.0291 0.0685 0.0685
Brugia malayi Disorganized muscle protein 1 0.0137 0.0131 0.0112
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Brugia malayi Thioredoxin reductase 0.2877 1 1
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0308 0.0746 0.0728
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0326 0.0813 0.0813
Echinococcus multilocularis rac serine:threonine kinase 0.0317 0.0781 0.0781
Echinococcus multilocularis serine:threonine protein kinase 38 0.0311 0.0759 0.0759
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0224 0.0206
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0326 0.0813 0.0813
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0124 0.0083 0.0076
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0227 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0709 0.2191 0.2191
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0126 0.009 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0465 0.1423
Schistosoma mansoni titin 0.0137 0.0131 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.0392 0.1049 0.1049
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0308 0.0746 0.0728
Plasmodium falciparum glycogen synthase kinase 3 0.0249 0.0534 0.049
Plasmodium falciparum calcium-dependent protein kinase 5 0.0195 0.034 0.0295
Trichomonas vaginalis CMGC family protein kinase 0.023 0.0465 0.1423
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Echinococcus granulosus tyrosine protein kinase otk 0.03 0.0717 0.0717
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0474 0.1344 0.1344
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0162 0.0222 0.0222
Echinococcus multilocularis twitchin 0.0201 0.0361 0.0361
Trichomonas vaginalis STE family protein kinase 0.0263 0.0586 0.1797
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Loa Loa (eye worm) AUR protein kinase 0.0227 0.0456 0.0449
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0265 0.0591 0.0573
Loa Loa (eye worm) hypothetical protein 0.023 0.0466 0.0459
Trichomonas vaginalis mercuric reductase, putative 0.0997 0.3229 1
Schistosoma mansoni hypothetical protein 0.0197 0.0347 0.0347
Brugia malayi Protein kinase domain containing protein 0.0221 0.0433 0.0415
Echinococcus granulosus cyclin dependent kinase 9 0.0156 0.0198 0.0198
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Echinococcus multilocularis Glutaredoxin protein 5 0.0239 0.0498 0.0498
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0164 0.0228 0.0824
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0613 0.1846 0.184
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0126 0.0092 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.078 0.078
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0997 0.3229 0.3165
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0217 0.0217
Brugia malayi Protein kinase domain containing protein 0.0126 0.0092 0.0073
Echinococcus granulosus roundabout 2 0.0317 0.078 0.078
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0161 0.0217 0.0125
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0216 0.0415 0.0415
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0174 0.0263 0.0257
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0157 0.0204 0.0611
Schistosoma mansoni tyrosine kinase 0.0181 0.0289 0.0289
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0265 0.0591 0.0547
Echinococcus multilocularis protein kinase c epsilon type 0.0394 0.1058 0.1058
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0265 0.0591 0.1812
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0425 0.0425
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0222 0.0222
Brugia malayi P38 map kinase family protein 2 0.0308 0.0746 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0279 0.0279
Giardia lamblia Kinase, CAMK CAMKL 0.0167 0.024 0.0478
Trypanosoma cruzi casein kinase II, putative 0.0194 0.0335 0.0317
Onchocerca volvulus Basement membrane proteoglycan homolog 0.03 0.0717 0.2765
Entamoeba histolytica protein kinase 2, putative 0.0303 0.0728 0.2639
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0151 0.0182 0.0182
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0997 0.3229 0.3197
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0577 0.0577
Echinococcus granulosus fibroblast growth factor receptor 4 0.035 0.0899 0.0899
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0425 0.0425
Brugia malayi cell division control protein 2 homolog 0.023 0.0465 0.0447
Echinococcus multilocularis purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0471 0.1334 0.1334
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.1519 0.1519
Leishmania major protein kinase, putative 0.0297 0.0708 0.062
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0195 0.034 0.034
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0144 0.0157 0.0157
Trypanosoma cruzi cdc2-related kinase 3 0.023 0.0465 0.0447
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0331 0.083 0.0823
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0265 0.0591 0.0591
Loa Loa (eye worm) hypothetical protein 0.0154 0.0194 0.0187
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.021 0.0395 0.0388
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0265 0.0591 0.1711
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0421 0.1153 0.1147
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0263 0.0263
Loa Loa (eye worm) LAD-2 short isoform 0.0163 0.0224 0.0217
Echinococcus multilocularis lachesin 0.03 0.0717 0.0717
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0157 0.0204 0.0185
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0241 0.0504 0.046
Loa Loa (eye worm) TK/INSR protein kinase 0.0578 0.1721 0.1715
Echinococcus granulosus thioredoxin glutathione reductase 0.2877 1 1
Onchocerca volvulus 0.0537 0.1571 0.6174
Onchocerca volvulus 0.0216 0.0415 0.1561
Echinococcus granulosus purine nucleoside phosphorylase 0.0126 0.009 0.009
Echinococcus granulosus epidermal growth factor receptor 0.0667 0.2038 0.2038
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0997 0.3229 0.3165
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0297 0.0708 0.062
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Loa Loa (eye worm) hypothetical protein 0.0703 0.2171 0.2166
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0154 0.0194 0.0187
Loa Loa (eye worm) CAMK protein kinase 0.0218 0.0424 0.0417
Plasmodium falciparum glutathione reductase 0.0997 0.3229 0.3197
Schistosoma mansoni cell adhesion molecule 0.0163 0.0224 0.0224
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0445 0.124 0.124
Toxoplasma gondii casein kinase I 0.021 0.0395 0.035
Entamoeba histolytica thioredoxin reductase, putative 0.0265 0.0591 0.214
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0541 0.1585 0.1585
Schistosoma mansoni nck2/grb4 0.0118 0.0064 0.0064
Echinococcus granulosus C type lectin domian containing protein 0.0537 0.1571 0.1571
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0311 0.0759 0.0759
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0865 0.2754 0.2754
Brugia malayi Tyrosine-protein kinase abl-1 0.0181 0.0289 0.0271
Schistosoma mansoni purine nucleoside phosphorylase 0.0126 0.009 0.009
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0541 0.1585 0.1585
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.035 0.0899 0.0899
Echinococcus granulosus calcium activated potassium channel 0.0261 0.0577 0.0577
Trichomonas vaginalis CAMK family protein kinase 0.0151 0.0182 0.0544
Brugia malayi Immunoglobulin domain containing protein 0.0163 0.0224 0.0206
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0219 0.0425 0.0425
Trichomonas vaginalis CAMK family protein kinase 0.0539 0.1577 0.4874
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0157 0.0204 0.0185
Loa Loa (eye worm) hypothetical protein 0.0291 0.0685 0.0678
Schistosoma mansoni serine/threonine protein kinase 0.0261 0.0577 0.0577
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0163 0.0224 0.0224
Schistosoma mansoni septate junction protein 0.0163 0.0224 0.0224
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0449 0.1254 0.1248
Loa Loa (eye worm) hypothetical protein 0.0173 0.0259 0.0252
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0388 0.1036 0.1029
Brugia malayi Sushi domain 0.0537 0.1571 0.1555
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0415 0.0397
Leishmania major protein kinase A catalytic subunit 0.0219 0.0425 0.0335
Schistosoma mansoni tyrosine kinase 0.0553 0.1629 0.1629
Brugia malayi C1-like domain containing protein 0.0421 0.1153 0.1136
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0226 0.0207
Onchocerca volvulus 0.0291 0.0685 0.2636
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0157 0.0202 0.0157
Mycobacterium tuberculosis Probable oxidoreductase 0.0997 0.3229 0.3197
Echinococcus granulosus delta-like protein 1 0.0291 0.0685 0.0685
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0294 0.0698 0.0698
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1369 0.457 0.4566
Echinococcus granulosus Protein kinase C brain isozyme 0.0471 0.1334 0.1334
Brugia malayi Immunoglobulin I-set domain containing protein 0.03 0.0717 0.07
Plasmodium falciparum protein kinase, putative 0.0127 0.0093 0.0047
Echinococcus multilocularis aurora kinase A 0.0227 0.0456 0.0456
Schistosoma mansoni basigin related 0.0163 0.0224 0.0224
Brugia malayi Egg laying defective protein 4 0.0162 0.0222 0.0204
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0762 0.2382 0.2382
Onchocerca volvulus 0.0137 0.0131 0.0425
Schistosoma mansoni basigin related 0.0163 0.0224 0.0224
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0166 0.0237 0.0237
Loa Loa (eye worm) hypothetical protein 0.0232 0.0474 0.0467
Entamoeba histolytica protein kinase, putative 0.0565 0.1672 0.6055
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0156 0.0198 0.0191
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0294 0.0698 0.0698
Echinococcus granulosus neuroglian 0.0317 0.078 0.078
Echinococcus multilocularis calcium activated potassium channel 0.0261 0.0577 0.0577
Schistosoma mansoni nephrin 0.0317 0.078 0.078
Loa Loa (eye worm) hypothetical protein 0.0537 0.1571 0.1565
Echinococcus multilocularis titin 0.0137 0.0131 0.0131
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0265 0.0591 0.0573
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0216 0.0415 0.0397
Trichomonas vaginalis AGC family protein kinase 0.0565 0.1672 0.5168
Brugia malayi Casein kinase II, alpha chain 0.0194 0.0335 0.0317
Loa Loa (eye worm) hypothetical protein 0.0163 0.0224 0.0217
Brugia malayi map kinase activated protein kinase protein 2 0.0762 0.2382 0.2367
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0137 0.0133 0.0133
Brugia malayi Calcium binding EGF domain containing protein 0.0291 0.0685 0.0667
Schistosoma mansoni serine/threonine protein kinase 0.0681 0.2092 0.2092
Trichomonas vaginalis CMGC family protein kinase 0.0269 0.0606 0.1858
Toxoplasma gondii rhoptry neck protein RON1 0.0537 0.1571 0.1532
Plasmodium vivax calcium-dependent protein kinase, putative 0.0195 0.034 0.0295
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0265 0.0591 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.1142 0.1142
Loa Loa (eye worm) hypothetical protein 0.0137 0.0131 0.0124
Onchocerca volvulus Slit protein homolog 0.0334 0.0839 0.3251
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0216 0.0415 0.0415
Schistosoma mansoni hypothetical protein 0.0137 0.0131 0.0131
Schistosoma mansoni septate junction protein 0.0291 0.0685 0.0685
Toxoplasma gondii NADPH-glutathione reductase 0.0997 0.3229 0.3197
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0681 0.2092 0.2092
Leishmania major hypothetical protein, conserved 0.0265 0.0591 0.0502

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 3 nM Effective concentration towards 5-hydroxytryptamine 2A receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 3 nM Effective concentration towards 5-hydroxytryptamine 2A receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 80 nM Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 80 nM Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 220 nM Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408
EC50 (functional) = 220 nM Effective concentration towards 5-hydroxytryptamine 2C receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol release ChEMBL. 15713408

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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