Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | carboxylesterase | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1047 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0177 | 0.1543 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.1047 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | carboxylesterase | 0.1047 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1047 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0177 | 0.1543 | 0.1543 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Brugia malayi | Carboxylesterase family protein | 0.0177 | 0.1543 | 0.1543 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1047 | 1 | 1 |
Onchocerca volvulus | 0.0177 | 0.1543 | 1 | |
Echinococcus granulosus | carboxylesterase 5A | 0.1047 | 1 | 1 |
Onchocerca volvulus | 0.0177 | 0.1543 | 1 | |
Echinococcus multilocularis | acetylcholinesterase | 0.1047 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0177 | 0.1543 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Echinococcus multilocularis | acetylcholinesterase | 0.1047 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1047 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0177 | 0.1543 | 0.1543 |
Brugia malayi | Carboxylesterase family protein | 0.1047 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0177 | 0.1543 | 0.1543 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0177 | 0.1543 | 0.1543 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0177 | 0.1543 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0177 | 0.1543 | 0.1543 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Onchocerca volvulus | 0.0177 | 0.1543 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.0177 | 0.1543 | 0.1543 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0177 | 0.1543 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0177 | 0.1543 | 0.1543 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0177 | 0.1543 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0177 | 0.1543 | 0.5 |
Onchocerca volvulus | 0.0177 | 0.1543 | 1 | |
Onchocerca volvulus | 0.0177 | 0.1543 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1047 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Loa Loa (eye worm) | hypothetical protein | 0.1047 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0177 | 0.1543 | 0.1543 |
Brugia malayi | Carboxylesterase family protein | 0.0177 | 0.1543 | 0.1543 |
Schistosoma mansoni | gliotactin | 0.0177 | 0.1543 | 0.1543 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | NA 0 uM | Inhibitory activity of the compound against human immunodeficiency virus type 1 (inactive>0.1) | ChEMBL. | 15603974 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.