Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0126 | 0 | 0.5 | |
Onchocerca volvulus | 0.0126 | 0 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0126 | 0 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0126 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0748 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0748 | 1 | 1 |
Onchocerca volvulus | 0.0126 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0748 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0748 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0748 | 1 | 1 |
Onchocerca volvulus | 0.0126 | 0 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0748 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0748 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0748 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0748 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0126 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0748 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0126 | 0 | 0.5 |
Onchocerca volvulus | 0.0126 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0748 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0126 | 0 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0126 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0748 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.