Detailed information for compound 317576

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 414.475 | Formula: C21H22N2O5S
  • H donors: 3 H acceptors: 5 LogP: 2.83 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCn1c2CCCCc2c2c1ccc(c2)NS(=O)(=O)c1ccc(cc1)O
  • InChi: 1S/C21H22N2O5S/c24-15-6-8-16(9-7-15)29(27,28)22-14-5-10-20-18(13-14)17-3-1-2-4-19(17)23(20)12-11-21(25)26/h5-10,13,22,24H,1-4,11-12H2,(H,25,26)
  • InChiKey: SFEURIWVUDPPCI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens prostaglandin D2 receptor 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) TOPoisomerase family member 0.0053 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.012 0.0203 0.0202
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0122 0.0207 0.0206
Brugia malayi Globin family protein 0.0017 0.0007 0.0005
Chlamydia trachomatis DNA gyrase subunit B 0.0053 0.0076 0.1438
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0009
Echinococcus granulosus phd:f box containing protein 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0017 0.0007 0.0059
Schistosoma mansoni opsin-like receptor 0.0018 0.0009 0.0008
Giardia lamblia Histone acetyltransferase GCN5 0.0119 0.0201 0.3857
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0109 0.0108
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.0513 1
Schistosoma mansoni hypothetical protein 0.0033 0.0038 0.0037
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0162 0.0283 0.0281
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0023 0.0031
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0176 0.737
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0091 0.0089
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Echinococcus multilocularis Smad4 0.0016 0.0006 0.0004
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0208 0.0206
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0011
Loa Loa (eye worm) cysteine protease 0.0016 0.0006 0.0005
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0234 0.0421 0.0572
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0092 0.009
Echinococcus granulosus cathepsin l1 0.0016 0.0006 0.0005
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0198 0.4692
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Leishmania major DNA topoisomerase type IB small subunit 0.274 0.5194 0.7067
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.0562 0.0561
Loa Loa (eye worm) DNA topoisomerase I 0.5264 1 1
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0274 0.0496 1
Echinococcus granulosus importin subunit beta 1 0.0029 0.003 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0005
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0187 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Plasmodium vivax DNA topoisomerase II, putative 0.0053 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0208 0.0206
Echinococcus granulosus ferritin 0.0026 0.0024 0.0023
Echinococcus multilocularis importin subunit beta 1 0.0029 0.003 0.0028
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0011 0.0009
Schistosoma mansoni DNA topoisomerase type I 0.3872 0.735 0.7349
Echinococcus multilocularis dna polymerase eta 0.006 0.0089 0.0087
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0122 0.0207 0.0206
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Chlamydia trachomatis DNA topoisomerase I 0.0274 0.0496 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0156 0.0155
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0059 0.0057
Plasmodium falciparum topoisomerase I 0.5264 1 1
Echinococcus granulosus inositol monophosphatase 1 0.0111 0.0187 0.0185
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0035 0.0047
Giardia lamblia Kinase, PLK 0.0095 0.0156 0.2965
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0011 0.0009
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.0109 0.0108
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0071 0.0109 0.0108
Brugia malayi steroid hormone receptor 0.0071 0.0109 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Echinococcus multilocularis lysosomal alpha glucosidase 0.0144 0.025 0.0248
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0009
Leishmania major importin beta-1 subunit, putative 0.0023 0.002 0.0027
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.0109 0.0108
Echinococcus multilocularis lamin dm0 0.0026 0.0025 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Loa Loa (eye worm) pax transcription factor protein 2 0.0233 0.0418 0.0417
Brugia malayi polk-prov protein 0.0038 0.0048 0.0046
Brugia malayi nuclear receptor RXR 0.0037 0.0046 0.0044
Onchocerca volvulus 0.0018 0.0009 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0109 0.0108
Schistosoma mansoni survival motor neuron protein 0.0145 0.0252 0.025
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0044 0.0042
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0017 0.0008 0.0007
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0128
Schistosoma mansoni prokaryotic DNA topoisomerase 0.028 0.0509 0.0507
Schistosoma mansoni Smad4 0.0016 0.0006 0.0004
Brugia malayi G protein-coupled receptor 0.0018 0.0009 0.0008
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni DNA polymerase eta 0.006 0.0089 0.0087
Echinococcus granulosus single minded 2 0.0035 0.0042 0.0041
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0059 0.008
Plasmodium falciparum DNA gyrase subunit B 0.0053 0.0076 0.0072
Brugia malayi acetyltransferase, GNAT family protein 0.0441 0.0815 0.0813
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0009 0.0008
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni DNA topoisomerase II 0.0053 0.0076 0.0075
Brugia malayi Probable DNA topoisomerase II 0.0053 0.0076 0.0075
Loa Loa (eye worm) hypothetical protein 0.0535 0.0994 0.0993
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0198 0.8318
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.0177 0.0175
Brugia malayi Globin family protein 0.0017 0.0007 0.0005
Schistosoma mansoni intermediate filament proteins 0.0026 0.0025 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Trypanosoma brucei metacaspase 0.0044 0.0059 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Schistosoma mansoni alpha-glucosidase 0.0117 0.0197 0.0196
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0059 0.008
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0022 0.003
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.005 0.0049
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0006 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0059 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0011 0.0009
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0084 0.0083
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0011 0.0087
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0006 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.0038 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0109 0.0108
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.0038 0.0037
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0016 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0074 0.0116 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Toxoplasma gondii SWI2/SNF2-containing protein 0.004 0.0051 0.0049
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0046 0.0044
Echinococcus granulosus lysosomal alpha glucosidase 0.0144 0.025 0.0248
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0084 0.0083
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.274 0.5194 0.7067
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) inositol-1 0.0111 0.0187 0.0185
Echinococcus multilocularis cysteine protease 0.0016 0.0006 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0004
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0002
Brugia malayi nuclear receptor NHR-88 0.0071 0.0109 0.0108
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Schistosoma mansoni hypothetical protein 0.0308 0.0562 0.0561
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0006 0.0004
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0054 0.0052
Schistosoma mansoni neuropeptide receptor 0.0018 0.0009 0.0008
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0017 0.0007 0.0005
Onchocerca volvulus 0.0041 0.0054 0.0588
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0116 0.0158
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0009 0.0008
Trypanosoma brucei DNA topoisomerase III, putative 0.0122 0.0207 0.028
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Brugia malayi hypothetical protein 0.0041 0.0054 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Brugia malayi G-protein coupled receptor 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0016 0.0006 0.005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.0109 0.0108
Brugia malayi PAS domain containing protein 0.0048 0.0066 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.0109 0.0108
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0009 0.0008
Schistosoma mansoni amine GPCR 0.0018 0.0009 0.0008
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0456 0.5141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Schistosoma mansoni terminal deoxycytidyl transferase 0.0034 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0086 0.0138 0.0136
Trichomonas vaginalis sucrase-isomaltase, putative 0.0044 0.0059 0.0637
Brugia malayi glutathione reductase 0.0046 0.0063 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Schistosoma mansoni hypothetical protein 0.0041 0.0054 0.0052
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0009 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0102 0.0101
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Brugia malayi RE15519p 0.0018 0.0009 0.0008
Toxoplasma gondii cathepsin CPL 0.0016 0.0006 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0092 0.009
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.01 0.0165 0.6903
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0053 0.0073
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0004 0.0003
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0109 0.0108
Loa Loa (eye worm) DNA topoisomerase III 0.0241 0.0433 0.0432
Entamoeba histolytica hypothetical protein 0.0106 0.0177 0.3366
Loa Loa (eye worm) CYP4Cod1 0.0031 0.0035 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0011 0.0009
Echinococcus multilocularis caspase 2 0.0086 0.0138 0.0136
Echinococcus multilocularis musashi 0.0026 0.0025 0.0024
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0034 0.003
Trypanosoma brucei DNA topoisomerase III, putative 0.0241 0.0433 0.0587
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0031 0.0319
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0419 0.0773 0.0772
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0006 0.0037
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0127 0.2385
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0009 0.0008
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0014
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0234 0.0421 0.4743
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0091 0.0089
Schistosoma mansoni single-minded 0.0048 0.0066 0.0064
Schistosoma mansoni apoferritin-2 0.0026 0.0024 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0042 0.0437
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0208 0.0206
Schistosoma mansoni neuropeptide receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0006 0.0005
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.0778 0.0776
Echinococcus granulosus dna polymerase kappa 0.0062 0.0093 0.0091
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0208 0.0206
Brugia malayi AKH receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0046 0.0044
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0006 0.0169
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0006 0.0037
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0011 0.0009
Loa Loa (eye worm) nuclear hormone receptor 0.0033 0.0038 0.0037
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.013 0.0222 0.022
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0006 0.0001
Echinococcus granulosus dna polymerase eta 0.006 0.0089 0.0087
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0111 0.0187 0.2088
Echinococcus granulosus survival motor neuron protein 1 0.0712 0.1332 0.1331
Echinococcus granulosus flap endonuclease 1 0.0025 0.0023 0.0021
Leishmania major DNA polymerase eta, putative 0.006 0.0089 0.0121
Loa Loa (eye worm) fibroinase 0.0016 0.0006 0.0005
Onchocerca volvulus 0.0018 0.0009 0.0085
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0009 0.0008
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0003
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.008 0.0127 0.2385
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0059 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0071 0.0109 0.0108
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0038 0.0037
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.0109 0.122
Leishmania major hypothetical protein, conserved 0.0015 0.0004 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Loa Loa (eye worm) hypothetical protein 0.0037 0.0046 0.0044
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0093 0.1018
Echinococcus multilocularis lamin 0.0026 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0038 0.0048 0.0046
Loa Loa (eye worm) globin family protein 0.0017 0.0007 0.0005
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0023 0.0331
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0004 0.0003
Schistosoma mansoni lamin 0.0026 0.0025 0.0024
Trypanosoma brucei polo-like protein kinase 0.0095 0.0156 0.021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus sex peptide receptor 0.0018 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0051 0.0071 0.007
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0022 0.0483
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0044 0.0059 0.0058
Onchocerca volvulus Globin homolog 0.0017 0.0007 0.0059
Schistosoma mansoni cpg binding protein 0.0031 0.0035 0.0033
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Echinococcus granulosus g protein coupled receptor 0.0018 0.0009 0.0008
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0053 0.0076 0.0075
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0033
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0421 0.0778 0.0776
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0166 0.0164
Trypanosoma cruzi hypothetical protein, conserved 0.0044 0.0059 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0011 0.0087
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0059 0.1035
Echinococcus multilocularis inositol monophosphatase 1 0.0111 0.0187 0.0185
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0042 0.0437
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0025 0.0024
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.0038 0.0037
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0109 0.0108
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0011 0.0009
Leishmania major DNA topoisomerase III, putative 0.028 0.0509 0.0692
Schistosoma mansoni adenoreceptor 0.0018 0.0009 0.0008
Plasmodium vivax glutathione reductase, putative 0.0046 0.0063 0.0062
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.0109 0.0108
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0012 0.0011
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0006 0.0002
Brugia malayi Steroid receptor seven-up type 2 0.0071 0.0109 0.0108
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0091 0.0089
Brugia malayi G-protein coupled receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0063 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0038 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Schistosoma mansoni inositol monophosphatase 0.0111 0.0187 0.0185
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0024 0.0956
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0006 0.0008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0093 0.1018
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0166 0.0164
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0009 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.0109 0.0108
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0006 0.0004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0044 0.0059 0.0058
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0034 0.0047
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0063 0.0062
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0069 0.0106 0.117
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Brugia malayi Cathepsin L-like precursor 0.0016 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0102 0.0101
Entamoeba histolytica hypothetical protein 0.0019 0.0011 0.0089
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0006 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0456 0.5141
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0025 0.0249
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0006 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0059 0.1044
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0009 0.0008
Toxoplasma gondii DNA topoisomerase I, putative 0.5264 1 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0059 0.0637
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0009 0.0008
Plasmodium falciparum metacaspase-like protein 0.0044 0.0059 0.0055
Echinococcus granulosus tar DNA binding protein 0.0061 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.012 0.0203 0.0202
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.0109 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0456 0.5141
Plasmodium falciparum thioredoxin reductase 0.0046 0.0063 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Brugia malayi ImpB/MucB/SamB family protein 0.006 0.0089 0.0087
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0164 0.0287 0.0286
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0009 0.0008
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0006 0.0004
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0004 0.0003
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0016 0.0014
Brugia malayi DNA topoisomerase III 0.0241 0.0433 0.0432
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.0038 0.0037
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0112 0.0111
Loa Loa (eye worm) RNA binding protein 0.0061 0.0092 0.009
Leishmania major cytochrome p450-like protein 0.0014 0.0002 0.0002
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.0177 0.0175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0059 0.0058
Giardia lamblia DNA topoisomerase III 0.0234 0.0421 0.8175
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0059 0.0057
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0011 0.0009
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.002 0.0188
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0176 0.737
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0059 0.064
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0109 0.0108
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0009 0.0008
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0042 0.0966
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0109 0.0108
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0198 0.8318
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0016 0.0006 0.0003
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0046 0.0044
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0111 0.0187 0.3565
Echinococcus granulosus cpg binding protein 0.0031 0.0035 0.0033
Brugia malayi RNA binding protein 0.0061 0.0092 0.009
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.3872 0.735 1
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0059 0.0081
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0059 0.0057
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0024 0.0366
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0015 0.0018
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0034 0.0033
Onchocerca volvulus 0.003 0.0031 0.0336
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0089 0.0087
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0004 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0088 0.0086
Brugia malayi hypoxia-induced factor 1 0.0147 0.0255 0.0254
Plasmodium falciparum histone acetyltransferase GCN5 0.0119 0.0201 0.0197
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Schistosoma mansoni myoglobin 1 0.0017 0.0007 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0011 0.0009
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0009 0.0085
Echinococcus multilocularis caspase 3 0.0073 0.0114 0.0112
Loa Loa (eye worm) hypothetical protein 0.016 0.0279 0.0277
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0042 0.0041
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0044 0.0059 0.1044
Onchocerca volvulus 0.0018 0.0009 0.0085
Brugia malayi neuropeptide F receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0071 0.0109 0.0108
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0034 0.0045
Schistosoma mansoni hypothetical protein 0.0499 0.0926 0.0924
Onchocerca volvulus 0.0018 0.0009 0.0085
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0011 0.0009
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0233 0.0418 0.4722
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.0156 0.0212
Leishmania major cytochrome p450-like protein 0.0014 0.0002 0.0002
Onchocerca volvulus 0.0477 0.0884 1
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0287 0.0286
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0005
Echinococcus granulosus caspase 3 0.0073 0.0114 0.0112
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0038 0.0037
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Brugia malayi RNA, U transporter 1 0.0082 0.0131 0.013
Echinococcus granulosus smad 0.0016 0.0006 0.0004
Schistosoma mansoni amine GPCR 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0061 0.0091 0.1007
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.0088 0.0086
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0059 0.0058
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0006 0.0004
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0011 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0009 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0093 0.0126
Echinococcus granulosus FTZ F1 alpha 0.0071 0.0109 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0059 0.0631
Brugia malayi Cathepsin L-like precursor 0.0016 0.0006 0.0005
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0011 0.0009
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0034 0.1384
Echinococcus granulosus neuropeptide receptor 0.0018 0.0009 0.0008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0176 0.4158
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0128
Toxoplasma gondii melibiase subfamily protein 0.01 0.0166 0.0164
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Brugia malayi PXA domain containing protein 0.0019 0.0011 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0092 0.009
Schistosoma mansoni cpg binding protein 0.0031 0.0035 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0059 0.064
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0004 0.0003
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0187 0.0254
Onchocerca volvulus 0.0016 0.0006 0.005
Echinococcus multilocularis cpg binding protein 0.0031 0.0035 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0712 0.1332 0.1331
Brugia malayi jmjC domain containing protein 0.0059 0.0088 0.0086
Onchocerca volvulus 0.0026 0.0025 0.0266
Trichomonas vaginalis DNA topoisomerase II, putative 0.0053 0.0076 0.0829
Brugia malayi jmjC domain containing protein 0.0015 0.0004 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0006 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0109 0.0108
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0031 0.003
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0255 0.0254
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0009 0.0008
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.0038 0.0037
Giardia lamblia DINP protein human, muc B family 0.0041 0.0053 0.0941
Brugia malayi ORL1-like opioid receptor 0.0018 0.0009 0.0008
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0034 0.004 0.0039
Echinococcus multilocularis survival motor neuron protein 1 0.0712 0.1332 0.1331
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0093 0.0126
Echinococcus multilocularis smad 0.0016 0.0006 0.0004
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0023 0.0021
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.0038 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0025 0.0249
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0089 0.0087
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0004 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0006 0.0037
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Brugia malayi Thioredoxin reductase 0.0046 0.0063 0.0062
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.0109 0.0108
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.0109 0.0108
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0067 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0011 0.0087
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0088 0.0086
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0009 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0092 0.009
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0513 1
Leishmania major DNA topoisomerase IB, large subunit 0.3872 0.735 1
Brugia malayi hypothetical protein 0.0033 0.0038 0.0037
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.0038 0.0037
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0105 0.0103
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Echinococcus multilocularis snurportin 1 0.0308 0.0562 0.0561
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0038 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0059 0.064
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.002 0.0027
Mycobacterium ulcerans hypothetical protein 0.0025 0.0022 0.0483
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0063 0.0062
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.0038 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0105 0.0143
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0208 0.4917
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0059 0.0057
Leishmania major trypanothione reductase 0.0046 0.0063 0.0086
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0006 0.0009
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0023 0.0021
Plasmodium vivax histone acetyltransferase GCN5, putative 0.013 0.0222 0.0221
Brugia malayi Nuclear hormone receptor E75 0.0033 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0028
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0042 0.0057
Echinococcus multilocularis caspase 8 0.0044 0.0059 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Brugia malayi Melatonin receptor type 1A 0.0018 0.0009 0.0008
Giardia lamblia DNA topoisomerase II 0.0053 0.0076 0.139
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0053 0.0076 0.0104
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0059 0.0078
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Echinococcus granulosus hypothetical protein 0.0692 0.1294 0.1292
Plasmodium vivax DNA gyrase subunit B, putative 0.0053 0.0076 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.0109 0.0108
Entamoeba histolytica DNA topoisomerase III, putative 0.0234 0.0421 0.8173
Entamoeba histolytica DNA topoisomerase II, putative 0.0053 0.0076 0.1379
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.0156 0.0155
Trypanosoma cruzi cytochrome P450, putative 0.0031 0.0035 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0009 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0441 0.0815 0.0813
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0025 0.0249
Brugia malayi Cell death protein 3 precursor 0.0086 0.0138 0.0136
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0053 0.0076 0.1438
Giardia lamblia DNA topoisomerase III 0.0122 0.0207 0.3972
Trypanosoma brucei DNA topoisomerase ii 0.0053 0.0076 0.0101
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Brugia malayi hypothetical protein 0.012 0.0203 0.0202
Onchocerca volvulus 0.0018 0.0009 0.0085
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0016 0.0006 0.0009
Schistosoma mansoni smad1 5 8 and 0.0016 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0046 0.0044
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0004
Echinococcus granulosus transcription factor Dp 1 0.0039 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0009 0.0008
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0006 0.0008
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0128
Echinococcus granulosus geminin 0.0499 0.0926 0.0924
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Brugia malayi tailless protein 0.0033 0.0038 0.0037
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0084 0.0083
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0011 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.0109 0.0108
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0053 0.219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0059 0.0631
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0004 0.0003
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0006 0.0037
Plasmodium falciparum glutathione reductase 0.0046 0.0063 0.0059
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.0038 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0006 0.0028
Onchocerca volvulus 0.0017 0.0007 0.0059
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0038 0.0415
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.0109 0.0108
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0044 0.0059 0.0058
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0059 0.0637
Brugia malayi ecdysteroid receptor 0.0071 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma brucei unspecified product 0.0024 0.002 0.0025
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0011 0.0009
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.0513 1
Entamoeba histolytica hypothetical protein 0.0023 0.002 0.0265
Echinococcus granulosus allatostatin A receptor 0.0018 0.0009 0.0008
Brugia malayi hypothetical protein 0.016 0.0279 0.0277
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0009 0.0008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0006 0.0004
Echinococcus granulosus Smad4 0.0016 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0065 0.0704
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0006 0.0008
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0122 0.0207 0.0206
Brugia malayi Inositol-1 0.0111 0.0187 0.0185
Onchocerca volvulus 0.0018 0.0009 0.0085
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0011
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0198 0.8318
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0048 0.0063
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.0112 0.0188 0.7907
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0009 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0477 0.0884 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0059 0.0637
Trichomonas vaginalis ferritin, putative 0.0026 0.0024 0.0239
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0116 0.0156
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0084 0.0083
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0208 0.4917
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0006 0.0037
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0009 0.0008
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0059 0.0058
Echinococcus granulosus muscleblind protein 0.029 0.0528 0.0527
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0006 0.0095
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0105 0.0141
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0009 0.0008
Schistosoma mansoni amine GPCR 0.0018 0.0009 0.0008
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0234 0.0421 0.4743
Schistosoma mansoni ferritin 0.0026 0.0024 0.0023
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.029 0.3273
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0025 0.0024
Loa Loa (eye worm) globin family protein 0.0017 0.0007 0.0005
Echinococcus multilocularis tumor protein p63 0.033 0.0604 0.0603
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0381 0.0518
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0023
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0059 0.008
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0208 0.0206
Schistosoma mansoni biogenic amine receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0006 0.0028
Schistosoma mansoni zinc finger protein 0.0033 0.0038 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.0109 0.0108
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0059 0.0637
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0059 0.0058
Plasmodium vivax vivapain-2 0.0016 0.0006 0.0005
Brugia malayi Glycosyl hydrolases family 31 protein 0.0144 0.025 0.0248
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0009 0.0008
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0003 0.0002
Loa Loa (eye worm) Smad1 0.0016 0.0006 0.0004
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0105 0.0103
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0166 0.0164
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.0109 0.0108
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0042 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.0109 0.0108
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0004
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0022 0.003
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0004 0.0003
Schistosoma mansoni coup transcription factor 0.0071 0.0109 0.0108
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.0038 0.0037
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0009 0.0008
Toxoplasma gondii DNA topoisomerase family protein 0.0234 0.0421 0.0419
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0042 0.0437
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Echinococcus granulosus histone acetyltransferase KAT2B 0.0428 0.0791 0.079
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Leishmania major glycosyl hydrolase-like protein 0.0016 0.0006 0.0009
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0023 0.0021
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0089 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.0109 0.0108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0042 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.274 0.5194 0.7066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Schistosoma mansoni caspase-7 (C14 family) 0.0086 0.0138 0.0136
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0116 0.0115
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0208 0.0282
Schistosoma mansoni hypothetical protein 0.0106 0.0177 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Echinococcus granulosus microtubule associated protein 2 0.0667 0.1246 0.1245
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0068 0.0093
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Leishmania major adenylate cyclase-like protein 0.0017 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0006 0.0035
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0044 0.0059 0.0058
Brugia malayi nuclear receptor RXR 0.0033 0.0038 0.0037
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0009 0.0008
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0238 0.5641
Onchocerca volvulus 0.0018 0.0009 0.0085
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0009 0.0008
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0023 0.0344
Brugia malayi larval opioid receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0009 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0006 0.0005
Schistosoma mansoni lamin 0.0026 0.0025 0.0024
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0053 0.0076 0.0075
Trypanosoma brucei metacaspase MCA3 0.0044 0.0059 0.0079
Echinococcus multilocularis muscleblind protein 0.029 0.0528 0.0527
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0092 0.009
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0011 0.0009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Leishmania major cathepsin L-like protease 0.0016 0.0006 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0091 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Brugia malayi conserved hypotetical protein 0.0033 0.0038 0.0037
Brugia malayi hypothetical protein 0.0019 0.0011 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0004 0.0003
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0002
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0105 0.1948
Trichomonas vaginalis maltase-glucoamylase, putative 0.0044 0.0059 0.0637
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0059 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0007 0.0006
Brugia malayi hypothetical protein 0.0037 0.0046 0.0044
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0024 0.0956
Brugia malayi isocitrate dehydrogenase 0.0031 0.0034 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0238 0.5641
Brugia malayi Importin beta-1 subunit 0.0029 0.003 0.0028
Leishmania major DNA topoisomerase III, putative 0.0122 0.0207 0.0282
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.0109 0.0108
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.0423 0.0421
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.0109 0.0108
Brugia malayi MH2 domain containing protein 0.0016 0.0006 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0033
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0063 0.2601
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Leishmania major hypothetical protein, conserved 0.0074 0.0116 0.0158
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0042 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0011 0.0087
Brugia malayi Melibiase family protein 0.0067 0.0102 0.0101
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0234 0.0421 0.0572
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0009 0.0008
Brugia malayi GnHR receptor homolog 0.0018 0.0009 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0166 0.0164
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Plasmodium falciparum DNA topoisomerase 3, putative 0.0234 0.0421 0.0417
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0059 0.0058
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0094 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.0109 0.0108
Plasmodium vivax topoisomerase I, putative 0.5264 1 1
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0053 0.0076 0.139
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0031 0.0035 0.0788
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0012 0.0011
Schistosoma mansoni biogenic amine receptor 0.0018 0.0009 0.0008
Brugia malayi putative neuropeptide receptor 0.0018 0.0009 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0128
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0059 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0456 0.5141
Brugia malayi hypothetical protein 0.0074 0.0116 0.0115
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0011 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0456 0.5141
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0022 0.003
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Echinococcus granulosus intermediate filament protein 0.0026 0.0025 0.0024
Brugia malayi Cathepsin L-like precursor 0.0016 0.0006 0.0005
Trypanosoma cruzi metacaspase, putative 0.0044 0.0059 0.0081
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0022 0.0483
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.0046 0.0044
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0089 0.2087
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.0038 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Brugia malayi hypothetical protein 0.0037 0.0046 0.0044
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0035 0.0033
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0009 0.0008
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0034 0.0033
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.0038 0.0037
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0018 0.0009 0.0085
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0034 0.0033
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.1246 0.1245
Onchocerca volvulus 0.0017 0.0007 0.0059
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0053 0.0076 0.0843
Brugia malayi Cytochrome P450 family protein 0.0033 0.0037 0.0036
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.0109 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0109 0.0108
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0033 0.0038 0.0415
Echinococcus granulosus caspase 0.0117 0.0198 0.0197
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0156 0.0212
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0025 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0048 0.0063
Echinococcus multilocularis geminin 0.0499 0.0926 0.0924
Onchocerca volvulus 0.0018 0.0009 0.0085
Trypanosoma brucei DNA polymerase eta, putative 0.006 0.0089 0.0119
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0024 0.0379
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0053 0.0076 0.0104
Leishmania major cathepsin L-like protease 0.0016 0.0006 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0059 0.064
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0004 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0213 0.0381 0.0516
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.0038 0.0415
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0307 0.3457
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0009 0.0008
Onchocerca volvulus Huntingtin homolog 0.012 0.0203 0.2282
Mycobacterium tuberculosis Probable reductase 0.0105 0.0176 0.737
Entamoeba histolytica Ran family GTPase 0.0021 0.0016 0.0184
Brugia malayi hypothetical protein 0.0017 0.0007 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0116 0.0112
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Echinococcus granulosus caspase 2 0.0086 0.0138 0.0136
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0009 0.0008
Treponema pallidum DNA topoisomerase I (topA) 0.0274 0.0496 0.9663
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.0456 0.0454
Brugia malayi DNA topoisomerase III beta-1 0.0122 0.0207 0.0206
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0011 0.0009
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0059 0.1035
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.0177 0.0175
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0111 0.0187 0.4424
Onchocerca volvulus Cell death protein 3 homolog 0.0086 0.0138 0.1544
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.003 0.0028
Echinococcus multilocularis expressed protein 0.0365 0.067 0.0668
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0011 0.0009
Brugia malayi intermediate filament protein 0.0026 0.0025 0.0024
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0009 0.0008
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0042 0.0437
Brugia malayi photoreceptor-specific nuclear receptor 0.0535 0.0994 0.0993
Brugia malayi hypothetical protein 0.0106 0.0177 0.0175
Loa Loa (eye worm) hypothetical protein 0.0026 0.0025 0.0024
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0011 0.0009
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0003 0.0002
Brugia malayi MH2 domain containing protein 0.0235 0.0423 0.0421
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0092 0.009
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0011 0.0009
Brugia malayi GRF zinc finger family protein 0.006 0.0089 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0004
Echinococcus multilocularis cysteine protease 0.0016 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Brugia malayi Protein kinase domain containing protein 0.0015 0.0003 0.0002
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0053 0.0076 0.0075
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.0234 0.0421 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0037 0.0046 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0009 0.0008
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0002 0.0002
Entamoeba histolytica DNA topoisomerase III, putative 0.0122 0.0207 0.3964
Trichomonas vaginalis bromodomain-containing protein, putative 0.013 0.0222 0.2486
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0009 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0033 0.0043
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0006 0.005
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0009 0.0008
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0009 0.0008
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0089 0.3699
Echinococcus multilocularis DNA topoisomerase 1 0.5264 1 1
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0016 0.0006 0.0052
Trypanosoma cruzi DNA topoisomerase III, putative 0.0241 0.0433 0.0589
Brugia malayi Globin family protein 0.0017 0.0007 0.0005
Onchocerca volvulus 0.0018 0.0009 0.0085
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0111 0.0187 0.0185
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0066 0.0064
Brugia malayi TAR-binding protein 0.0061 0.0092 0.009
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0176 0.737
Onchocerca volvulus 0.0033 0.0038 0.0415
Trypanosoma brucei DNA topoisomerase IA, putative 0.0234 0.0421 0.057
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.0109 0.0108
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0053 0.0076 0.0843
Entamoeba histolytica hypothetical protein 0.0019 0.0011 0.0089
Trichomonas vaginalis importin beta-1, putative 0.0023 0.002 0.0188
Schistosoma mansoni opsin-like receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0009 0.0008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0011
Brugia malayi Dopamine receptor 0.0018 0.0009 0.0008
Trypanosoma cruzi metacaspase, putative 0.0044 0.0059 0.0081
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0089 0.0087
Echinococcus granulosus orexin receptor type 2 0.0018 0.0009 0.0008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0009 0.0008
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0044 0.0059 0.0058
Brugia malayi Protein kinase domain containing protein 0.0164 0.0287 0.0286
Onchocerca volvulus 0.0018 0.0009 0.0085
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0093 0.2175
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0011 0.0009
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0009 0.0008
Brugia malayi nuclear hormone receptor 0.0033 0.0038 0.0037
Plasmodium vivax JmjC domain containing protein 0.0015 0.0004 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0093 0.0124
Onchocerca volvulus 0.0017 0.0007 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Leishmania major DNA topoisomerase 1A 0.0234 0.0421 0.0572
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0156 0.2956
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0053 0.007
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0011 0.0009
Brugia malayi hypothetical protein 0.0019 0.0011 0.0009
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0011 0.0009
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0006 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0059 0.0058
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1577 0.2978 0.2977
Entamoeba histolytica hypothetical protein 0.0019 0.0011 0.0089
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.0046 0.0044
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0009 0.0008
Trypanosoma cruzi metacaspase, putative 0.0044 0.0059 0.0081
Schistosoma mansoni DNA topoisomerase type I 0.3872 0.735 0.7349
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Mycobacterium ulcerans monooxygenase 0.0017 0.0007 0.013
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.0109 0.122
Plasmodium falciparum metacaspase 1 0.0044 0.0059 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0059 0.0058
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0105 0.0103
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.0156 0.1749
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0011 0.0009
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0037 0.0036
Schistosoma mansoni amine GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) DR-78 0.0033 0.0038 0.0037
Trypanosoma cruzi DNA topoisomerase III, putative 0.0241 0.0433 0.0589
Schistosoma mansoni neuropeptide receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0034 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0071 0.0109 0.0108
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.0109 0.0108
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0441 0.0815 0.0813
Onchocerca volvulus 0.0018 0.0009 0.0085
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0105 0.0103
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.0109 0.122
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0006 0.0004
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0038 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0004 0.0003
Echinococcus granulosus g protein coupled receptor 0.0018 0.0009 0.0008
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.0109 0.0108
Echinococcus multilocularis serotonin receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Brugia malayi CXXC zinc finger family protein 0.003 0.0031 0.003
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0075 0.0073
Echinococcus multilocularis neutral alpha glucosidase AB 0.0044 0.0059 0.0058
Schistosoma mansoni flap endonuclease-1 0.0023 0.0018 0.0017
Schistosoma mansoni alpha-glucosidase 0.0117 0.0197 0.0196
Leishmania major GTP-binding protein, putative 0.0021 0.0016 0.0021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Echinococcus multilocularis somatostatin receptor 0.0018 0.0009 0.0008
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0034 0.0033
Brugia malayi jmjC domain containing protein 0.0057 0.0084 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.0156 0.0155
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0513 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0095
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0014
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0005
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0063 0.0086
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0307 0.3457
Echinococcus granulosus histone acetyltransferase KAT2B 0.013 0.0222 0.022
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0187 0.0254
Schistosoma mansoni nuclear receptor 0.0033 0.0038 0.0037
Trypanosoma brucei unspecified product 0.0055 0.008 0.0106
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0105 0.0143
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0009 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0004 0.0003
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0241 0.0433 0.0432
Plasmodium falciparum glutathione reductase 0.0016 0.0006 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0065 0.0704
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0009 0.0008
Brugia malayi jmjC domain containing protein 0.0015 0.0004 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0009 0.0008
Brugia malayi nuclear receptor NHR-88 0.0033 0.0038 0.0037
Echinococcus multilocularis conserved hypothetical protein 0.0674 0.126 0.1258
Brugia malayi MH1 domain containing protein 0.0016 0.0006 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.003 0.0039
Trypanosoma brucei metacaspase 5, putative 0.0044 0.0059 0.0079
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.0038 0.0037
Entamoeba histolytica deoxycytidyl transferase, putative 0.0034 0.004 0.0673
Schistosoma mansoni importin beta-1 0.0029 0.003 0.0028
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0093 0.2175
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0009 0.0008
Schistosoma mansoni ferritin 0.0026 0.0024 0.0023
Schistosoma mansoni globin X 0.0017 0.0007 0.0005
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0024 0.0539
Echinococcus granulosus lamin dm0 0.0026 0.0025 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0059 0.064
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0044 0.0059 0.0058
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0093 0.0126
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0023 0.0226
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.0038 0.0037
Plasmodium falciparum flap endonuclease 1 0.0025 0.0023 0.0019
Brugia malayi hypothetical protein 0.0712 0.1332 0.1331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0025 0.0243
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0107 0.0105
Leishmania major DNA polymerase eta, putative 0.0036 0.0044 0.006
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0009 0.0085
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus lamin 0.0026 0.0025 0.0024
Echinococcus granulosus tumor protein p63 0.033 0.0604 0.0603
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0093 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0004 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0044 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0006 0.0035
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0006 0.0004
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0111 0.0187 0.2088
Echinococcus multilocularis rho GTPase activating protein 20 0.0241 0.0433 0.0432
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0009 0.0008
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0011 0.0009
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0053 0.0076 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0093 0.0126
Trypanosoma brucei metacaspase MCA2 0.0044 0.0059 0.0079
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0083 0.0114
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0102 0.1125
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0061 0.0091 0.0089
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0009 0.0008
Brugia malayi neuropeptide F receptor 0.0018 0.0009 0.0008
Schistosoma mansoni biogenic amine receptor 0.0018 0.0009 0.0008
Leishmania major cathepsin L-like protease 0.0016 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0037 0.0046 0.0044
Brugia malayi Muscleblind-like protein 0.029 0.0528 0.0527
Toxoplasma gondii thioredoxin reductase 0.0046 0.0063 0.0062
Mycobacterium tuberculosis Probable monooxygenase 0.0017 0.0007 0.023
Schistosoma mansoni cpg binding protein 0.003 0.0031 0.003
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0011 0.0009
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0006 0.0004
Schistosoma mansoni nuclear receptor 0.0033 0.0038 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0213 0.0381 0.0518
Mycobacterium tuberculosis Conserved hypothetical protein 0.0034 0.004 0.1641
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Brugia malayi jmjC domain containing protein 0.0015 0.0004 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0016 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Trypanosoma cruzi DNA polymerase eta, putative 0.006 0.0089 0.0121
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0023 0.0029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0007
Onchocerca volvulus 0.006 0.009 0.1002
Onchocerca volvulus 0.0018 0.0009 0.0085
Echinococcus granulosus serotonin receptor 0.0018 0.0009 0.0008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0009 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0513 0.5795
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0102 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0016 0.0006 0.005
Schistosoma mansoni nuclear hormone receptor 0.0033 0.0038 0.0037
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0009 0.0008
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0009
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0009 0.0008
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.0038 0.0037
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0009 0.0008
Echinococcus multilocularis caspase 0.0117 0.0198 0.0197
Entamoeba histolytica acetyltransferase, GNAT family 0.0119 0.0201 0.3849
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0122 0.0207 0.0206
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.029 0.3264
Leishmania major cathepsin L-like protease 0.0016 0.0006 0.0008
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0109 0.0108
Loa Loa (eye worm) acetyltransferase 0.0441 0.0815 0.0813
Onchocerca volvulus 0.0071 0.0109 0.122
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.0456 0.5141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.0109 0.0108
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.013 0.0222 0.2486
Trichomonas vaginalis ran, putative 0.0021 0.0016 0.0141
Schistosoma mansoni ran 0.0021 0.0016 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0033 0.0043
Brugia malayi Cytochrome P450 family protein 0.0031 0.0035 0.0033
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Leishmania major hypothetical protein, conserved 0.0213 0.0381 0.0518
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.0423 0.0421
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0009 0.0008
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0009 0.0008
Brugia malayi hypothetical protein 0.0017 0.0007 0.0005
Brugia malayi nuclear hormone receptor 0.0071 0.0109 0.0108
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.0109 0.0108
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0022 0.0483
Schistosoma mansoni inositol monophosphatase 0.0111 0.0187 0.0185
Schistosoma mansoni ferritin light chain 0.0026 0.0024 0.0023
Echinococcus multilocularis lysosomal alpha glucosidase 0.0144 0.025 0.0248
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0004 0.0003
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0011 0.0009
Schistosoma mansoni hypothetical protein 0.0499 0.0926 0.0924
Leishmania major DNA polymerase kappa, putative 0.0041 0.0053 0.0073
Echinococcus granulosus somatostatin receptor 0.0018 0.0009 0.0008
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0004 0.0003
Onchocerca volvulus 0.0018 0.0009 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Schistosoma mansoni alpha glucosidase 0.0044 0.0059 0.0058
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0034 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Loa Loa (eye worm) hypothetical protein 0.0041 0.0054 0.0052
Brugia malayi hypothetical protein 0.0033 0.0038 0.0037
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0009 0.0008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0085 0.0084
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0145 0.0252 0.025
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0009 0.0008
Brugia malayi Pax transcription factor protein 2 0.0233 0.0418 0.0417
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0024 0.0539
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Entamoeba histolytica hypothetical protein 0.0106 0.0177 0.3366
Trypanosoma brucei unspecified product 0.0024 0.002 0.0025
Schistosoma mansoni histamine h1 receptor 0.0018 0.0009 0.0008
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0006 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0003 0.0002
Trypanosoma cruzi metacaspase, putative 0.0044 0.0059 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0053 0.0076 0.0843
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0111 0.0187 0.0254
Brugia malayi Pre-SET motif family protein 0.0061 0.0091 0.0089
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0089 0.2087
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0009 0.0008
Leishmania major mitochondrial DNA topoisomerase II 0.0053 0.0076 0.0104
Brugia malayi Cathepsin L-like precursor 0.0016 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0067 0.0066
Onchocerca volvulus 0.0016 0.0006 0.005
Trypanosoma brucei glucosidase, putative 0.0044 0.0059 0.0078
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0009 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0009 0.0008
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0034 0.0047
Loa Loa (eye worm) ctsf protein 0.0016 0.0006 0.0005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0034 0.004 0.0039
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0004 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0109 0.0108
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0005
Schistosoma mansoni smad 0.0016 0.0006 0.0004
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.0156 0.0155
Brugia malayi hypothetical protein 0.0017 0.0007 0.0005
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Onchocerca volvulus 0.0122 0.0207 0.2329
Loa Loa (eye worm) hypothetical protein 0.006 0.0089 0.0087
Brugia malayi hypothetical protein 0.0017 0.0007 0.0005
Plasmodium falciparum importin beta, putative 0.0029 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Brugia malayi Cytochrome P450 family protein 0.0031 0.0035 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0006 0.0008
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0004
Brugia malayi Serotonin receptor 0.0018 0.0009 0.0008
Brugia malayi Cathepsin L-like precursor 0.0016 0.0006 0.0005
Plasmodium falciparum thioredoxin reductase 0.0016 0.0006 0.0001
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0117 0.0198 0.0197
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Brugia malayi MH2 domain containing protein 0.0016 0.0006 0.0004
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0006 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0019
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.0038 0.0037
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0053 0.0076 0.0075
Trichomonas vaginalis alpha-glucosidase, putative 0.0016 0.0006 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0059 0.0631
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0016 0.0006 0.005
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.0109 0.0108
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0063 0.0062
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0208 0.4917
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0116 0.0115
Brugia malayi PXA domain containing protein 0.0019 0.0011 0.0009
Brugia malayi Cathepsin L-like precursor 0.0016 0.0006 0.0005
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0128
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0059 0.008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.0156 0.0155
Schistosoma mansoni ferritin 0.0026 0.0024 0.0023
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0021
Schistosoma mansoni neuropeptide receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0006 0.0005
Brugia malayi MH1 domain containing protein 0.0016 0.0006 0.0004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0044 0.0059 0.064
Schistosoma mansoni caspase-7 (C14 family) 0.0117 0.0198 0.0197
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0034 0.0045
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0011 0.0009
Plasmodium vivax metacaspase 1, putative 0.0044 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.029 0.0528 0.0527
Onchocerca volvulus 0.0048 0.0067 0.074
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0011 0.0009
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0022 0.0212
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0035 0.0042 0.0456
Brugia malayi hypothetical protein 0.0048 0.0066 0.0065
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0091 0.0089
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0091 0.0089
Onchocerca volvulus 0.0026 0.0025 0.0266
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Echinococcus granulosus dnaJ subfamily B 0.0421 0.0778 0.0776
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0238 1
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0156 0.1738
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0034 0.004 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0093 0.0124
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0042 0.0041
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0088 0.0086
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0006 0.0005
Brugia malayi jmjC domain containing protein 0.0015 0.0004 0.0003
Onchocerca volvulus Huntingtin homolog 0.012 0.0203 0.2282
Schistosoma mansoni kinase 0.0049 0.0067 0.0066
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.013 0.0222 0.022
Schistosoma mansoni myosin xvIII 0.0018 0.0009 0.0008
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Brugia malayi ImpB/MucB/SamB family protein 0.0034 0.004 0.0039
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.002 0.0188
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0009 0.0008
Loa Loa (eye worm) glutathione reductase 0.0046 0.0063 0.0062
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.0038 0.0037
Echinococcus granulosus snurportin 1 0.0308 0.0562 0.0561
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.001 0.0011
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.0038 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Trypanosoma brucei Metacaspase-4 0.0044 0.0059 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Plasmodium vivax vivapain-2 0.0016 0.0006 0.0005
Schistosoma mansoni DNA topoisomerase type I 0.5264 1 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0004 0.0006
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus multilocularis sex peptide receptor 0.0018 0.0009 0.0008
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.029 0.0528 0.0527
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0105 0.0103
Onchocerca volvulus 0.0018 0.0009 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0046 0.0493
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.0038 0.0037
Echinococcus granulosus caspase 8 0.0044 0.0059 0.0058
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0009 0.0008
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0112 0.0111
Loa Loa (eye worm) hypothetical protein 0.0044 0.0059 0.0058
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0059 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0037 0.0388
Brugia malayi Smad1 0.0016 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.008 0.0127 0.0126
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0029 0.0298
Mycobacterium ulcerans DNA gyrase subunit B 0.0053 0.0076 0.1779
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0059 0.0637
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Echinococcus granulosus DNA topoisomerase 1 0.5264 1 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0003 0.0002
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0054 0.0052
Brugia malayi Pre-SET motif family protein 0.0419 0.0773 0.0772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0126
Mycobacterium tuberculosis Conserved protein 0.0025 0.0022 0.0855
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Entamoeba histolytica hypothetical protein 0.0106 0.0177 0.3366
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0009 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.0109 0.0108
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0059 0.0058
Echinococcus granulosus expressed protein 0.0026 0.0024 0.0023
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0033 0.0043
Schistosoma mansoni ferritin 0.0026 0.0024 0.0023
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0006 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0006 0.0035
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0009 0.0008
Brugia malayi Glycosyl hydrolases family 31 protein 0.0016 0.0006 0.0005
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0002 0.0002
Echinococcus multilocularis thyroid hormone receptor alpha 0.0071 0.0109 0.0108
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.0046 0.0044
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0208 0.8715
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0016 0.0014
Entamoeba histolytica hypothetical protein 0.0106 0.0177 0.3366
Leishmania major alpha glucosidase II subunit, putative 0.0044 0.0059 0.008
Brugia malayi ecdysone receptor 0.0033 0.0038 0.0037
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.1246 0.1245
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0111 0.0187 0.3698
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0091 0.0089
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0022 0.002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0105 0.0143
Trypanosoma cruzi metacaspase 5, putative 0.0044 0.0059 0.0081
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0034 0.0033
Onchocerca volvulus 0.0017 0.0007 0.0059
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0034 0.0033
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0166 0.0164
Trichomonas vaginalis alpha-glucosidase, putative 0.0044 0.0059 0.0637
Schistosoma mansoni smad1 5 8 and 0.0016 0.0006 0.0004
Trichomonas vaginalis maltase-glucoamylase, putative 0.0016 0.0006 0.0037
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0166 0.0164
Plasmodium vivax SET domain protein, putative 0.0061 0.0091 0.009
Echinococcus multilocularis serotonin receptor 0.0018 0.0009 0.0008
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0116 0.0158
Trypanosoma brucei glycosyl hydrolase-like protein 0.0016 0.0006 0.0007
Onchocerca volvulus 0.0018 0.0009 0.0085
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0005
Schistosoma mansoni amine GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0033 0.0038 0.0037
Schistosoma mansoni smad1 5 8 and 0.0016 0.0006 0.0004
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0089 0.0121
Schistosoma mansoni hypothetical protein 0.0145 0.0252 0.025
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0012 0.0011
Schistosoma mansoni opsin-like receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0018 0.0009 0.0008
Echinococcus granulosus neuropeptide receptor 0.0018 0.0009 0.0008
Echinococcus multilocularis expressed protein 0.0026 0.0024 0.0023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0044 0.0059 0.0637
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0034 0.0033
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0017 0.0007 0.0005
Onchocerca volvulus 0.0016 0.0006 0.005
Mycobacterium ulcerans hypothetical protein 0.0025 0.0022 0.0483
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0006 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.0109 0.0108
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0046 0.0044
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.01 0.0165 0.3894
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0023 0.0022
Brugia malayi nuclear receptor NHR-67 0.0033 0.0038 0.0037
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0007 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0009 0.0008
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.008 0.0106
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0006 0.0004
Trypanosoma brucei cytochrome P450, putative 0.0031 0.0035 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0059 0.064
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.0109 0.0108
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0002 0.0002
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0006 0.0005
Mycobacterium ulcerans DNA topoisomerase I 0.0234 0.0421 1
Toxoplasma gondii DNA topoisomerase 2, putative 0.0053 0.0076 0.0075
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0009 0.0008
Echinococcus granulosus neutral alpha glucosidase AB 0.0044 0.0059 0.0058
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0059 0.0057
Brugia malayi Dopamine receptor protein 2 0.0018 0.0009 0.0008
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0145 0.0252 0.2834
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0091 0.0089
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0009 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.0109 0.0108
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0022 0.0855
Plasmodium vivax importin-beta 2, putative 0.0029 0.003 0.0029
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0006 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0109 0.0108
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0166 0.0164
Brugia malayi Flap endonuclease-1 0.0025 0.0023 0.0021
Leishmania major cytochrome p450-like protein 0.0031 0.0035 0.0047
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.0156 0.0212
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0016 0.0006 0.0037
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.0109 0.0108
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0117 0.0198 0.0197
Trichomonas vaginalis inositol monophosphatase, putative 0.0111 0.0187 0.2088
Chlamydia trachomatis DNA gyrase subunit B 0.0053 0.0076 0.1438
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0093 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0011 0.0087
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0004 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0009 0.0008
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0011 0.0087
Brugia malayi sulfakinin receptor protein 0.0018 0.0009 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0025 0.0243
Echinococcus multilocularis ferritin 0.0026 0.0024 0.0023
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0009 0.0008
Echinococcus multilocularis muscleblind protein 1 0.029 0.0528 0.0527
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0176 0.737
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Schistosoma mansoni apoferritin-2 0.0026 0.0024 0.0023
Giardia lamblia GTOR 0.0044 0.0059 0.1047
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0099 0.0097
Plasmodium falciparum DNA topoisomerase 2 0.0053 0.0076 0.0072
Leishmania major cathepsin L-like protease 0.0016 0.0006 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0009 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0011 0.0087
Echinococcus granulosus g protein coupled receptor 0.0018 0.0009 0.0008
Trypanosoma brucei trypanothione reductase 0.0046 0.0063 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0012 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0011 0.0009
Brugia malayi hypothetical protein 0.0018 0.0009 0.0008
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0006 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0009 0.0008
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0009
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0003 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0022 0.002
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0009 0.0008
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0011 0.0009
Plasmodium vivax DNA topoisomerase 3, putative 0.0234 0.0421 0.042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0009 0.0008
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0144 0.025 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0006 0.0035
Echinococcus granulosus fmrfamide receptor 0.0018 0.0009 0.0008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.0109 0.0108
Schistosoma mansoni caspase-3 (C14 family) 0.0117 0.0198 0.0197
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.0009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0006 0.0008
Trypanosoma cruzi DNA topoisomerase III, putative 0.0122 0.0207 0.0282
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0009 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0037 0.0046 0.0044
Leishmania major metacaspase, putative 0.0044 0.0059 0.0081
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.3872 0.735 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0109 0.0108
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0053 0.0076 0.3154
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0006 0.0005
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0023 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0116 0.0112
Brugia malayi Dopamine receptor protein 1 0.0018 0.0009 0.0008
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0024 0.0539
Brugia malayi Serotonin receptor 0.0018 0.0009 0.0008
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0006 0.0004
Echinococcus granulosus expressed protein 0.0365 0.067 0.0668
Schistosoma mansoni ferritin light chain 0.0026 0.0024 0.0023
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0176 0.737
Echinococcus multilocularis 0.0376 0.0691 0.0689
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.0456 0.0454
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0009 0.0008
Onchocerca volvulus 0.0018 0.0009 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.002 0.0194
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0003
Schistosoma mansoni ran 0.0021 0.0016 0.0014

Activities

Activity type Activity value Assay description Source Reference
Ki (functional) = 7.4 uM Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes ChEMBL. 15745833
Ki (functional) = 7.4 uM Inhibitory activity of the compound for binding of PGD-2 to CRTH-2 in hCRTH-2 binding assay using HEK293 cell membranes ChEMBL. 15745833

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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