Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0227 | 0.3105 | 0.5 |
Mycobacterium ulcerans | thymidylate synthase | 0.0227 | 0.3105 | 0.5 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0214 | 0.2705 | 0.2705 |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Loa Loa (eye worm) | cathepsin B | 0.0174 | 0.146 | 0.146 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Echinococcus granulosus | notch | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0451 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0147 | 0.0636 | 0.0636 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0214 | 0.2705 | 0.2198 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0214 | 0.2705 | 0.2705 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Brugia malayi | GCC2 and GCC3 family protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cathepsin L-like precursor | 0.0214 | 0.2705 | 0.2705 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Loa Loa (eye worm) | ctsf protein | 0.0214 | 0.2705 | 0.2705 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0174 | 0.146 | 0.0866 |
Schistosoma mansoni | slit | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0214 | 0.2705 | 0.2705 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | protein jagged 2 | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | delta-like protein 1 | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | cathepsin b | 0.0451 | 1 | 1 |
Schistosoma mansoni | notch | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.2705 | 0.2705 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0451 | 1 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.032 | 0.5958 | 1 |
Schistosoma mansoni | notch | 0.0147 | 0.0636 | 0.0636 |
Entamoeba histolytica | cysteine protease, putative | 0.0214 | 0.2705 | 1 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.032 | 0.5958 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cathepsin L-like precursor | 0.0214 | 0.2705 | 0.2705 |
Schistosoma mansoni | notch | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | fibropellin Ia | 0.0147 | 0.0636 | 0.0636 |
Toxoplasma gondii | cathepsin CPL | 0.0214 | 0.2705 | 0.454 |
Echinococcus multilocularis | neural cadherin | 0.0147 | 0.0636 | 0.0636 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | Slit protein homolog | 0.0147 | 0.0636 | 0.2047 |
Loa Loa (eye worm) | notch protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus multilocularis | cysteine protease | 0.0214 | 0.2705 | 0.2705 |
Echinococcus multilocularis | notch | 0.0147 | 0.0636 | 0.0636 |
Echinococcus multilocularis | cathepsin b | 0.0451 | 1 | 1 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0227 | 0.3105 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0451 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0174 | 0.146 | 1 |
Onchocerca volvulus | 0.0147 | 0.0636 | 0.2047 | |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0451 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.065 | 0.065 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cathepsin L-like precursor | 0.0148 | 0.065 | 0.065 |
Loa Loa (eye worm) | cysteine protease | 0.0214 | 0.2705 | 0.2705 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0214 | 0.2705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | notch | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | thymidylate synthase | 0.0227 | 0.3105 | 0.3105 |
Echinococcus multilocularis | slit 2 protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Onchocerca volvulus | 0.0147 | 0.0636 | 0.2047 | |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | Cathepsin L homolog | 0.0214 | 0.2705 | 0.8713 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0214 | 0.2705 | 0.2198 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.065 | 0.065 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Brugia malayi | notch-like transmembrane receptor | 0.0147 | 0.0636 | 0.0636 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Loa Loa (eye worm) | thymidylate synthase | 0.0227 | 0.3105 | 0.3105 |
Schistosoma mansoni | cell polarity protein | 0.0147 | 0.0636 | 0.0636 |
Toxoplasma gondii | cathepsin B | 0.0174 | 0.146 | 0.245 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0147 | 0.0636 | 0.2047 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0214 | 0.2705 | 0.2705 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0214 | 0.2705 | 0.2705 |
Echinococcus granulosus | neural cadherin | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cathepsin L-like precursor | 0.0214 | 0.2705 | 0.2705 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0451 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cathepsin L-like precursor | 0.0214 | 0.2705 | 0.2705 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Muscle positioning protein 4 | 0.0147 | 0.0636 | 0.0636 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0147 | 0.0636 | 0.1067 |
Onchocerca volvulus | 0.0147 | 0.0636 | 0.2047 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0214 | 0.2705 | 0.2705 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cadherin domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0214 | 0.2705 | 0.2705 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Echinococcus multilocularis | fibropellin Ia | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0227 | 0.3105 | 0.3105 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.032 | 0.5958 | 0.5677 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0174 | 0.146 | 0.394 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Echinococcus multilocularis | thymidylate synthase | 0.0227 | 0.3105 | 0.3105 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0451 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0147 | 0.0636 | 0.0636 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | thymidylate synthase | 0.0227 | 0.3105 | 0.3105 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.032 | 0.5958 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Delta serrate ligand family protein | 0.0147 | 0.0636 | 0.0636 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.032 | 0.5958 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0148 | 0.065 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0214 | 0.2705 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | 0.0147 | 0.0636 | 0.2047 | |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0147 | 0.0636 | 0.0636 |
Giardia lamblia | Cathepsin B precursor | 0.0174 | 0.146 | 1 |
Echinococcus granulosus | slit 2 protein | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0174 | 0.146 | 0.146 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0214 | 0.2705 | 0.2198 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | 0.0214 | 0.2705 | 0.8713 | |
Giardia lamblia | Cathepsin B precursor | 0.0174 | 0.146 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0214 | 0.2705 | 0.8713 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0214 | 0.2705 | 0.2705 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0214 | 0.2705 | 0.2705 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0147 | 0.0636 | 0.2047 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Echinococcus multilocularis | protein jagged 1 | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Onchocerca volvulus | 0.0227 | 0.3105 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Schistosoma mansoni | notch | 0.0147 | 0.0636 | 0.0636 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | fibroinase | 0.0214 | 0.2705 | 0.2705 |
Schistosoma mansoni | septate junction protein | 0.0147 | 0.0636 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0214 | 0.2705 | 0.2198 |
Onchocerca volvulus | 0.0147 | 0.0636 | 0.2047 | |
Echinococcus multilocularis | protein jagged 2 | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.065 | 0.065 |
Brugia malayi | Cathepsin L-like precursor | 0.0148 | 0.065 | 0.065 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | 0.0148 | 0.065 | 0.2094 | |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Echinococcus multilocularis | cysteine protease | 0.0214 | 0.2705 | 0.2705 |
Brugia malayi | EGF-like domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Leishmania major | cysteine peptidase A (CPA) | 0.0214 | 0.2705 | 0.2768 |
Echinococcus granulosus | protein jagged 1 | 0.0147 | 0.0636 | 0.0636 |
Echinococcus granulosus | cathepsin l1 | 0.0214 | 0.2705 | 0.2705 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0214 | 0.2705 | 0.2705 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | cathepsin L-like precursor | 0.0148 | 0.065 | 0.065 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0214 | 0.2705 | 0.2705 |
Brugia malayi | Cathepsin L-like precursor | 0.0214 | 0.2705 | 0.2705 |
Schistosoma mansoni | notch | 0.0147 | 0.0636 | 0.0636 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Brugia malayi | Cathepsin L-like precursor | 0.0214 | 0.2705 | 0.2705 |
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0214 | 0.2705 | 0.2768 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cadherin domain containing protein | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Leishmania major | cathepsin L-like protease | 0.0214 | 0.2705 | 0.2768 |
Echinococcus granulosus | cathepsin b | 0.0451 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0214 | 0.2705 | 0.8713 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.032 | 0.5958 | 1 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0147 | 0.0636 | 0.0636 |
Onchocerca volvulus | Putative cubilin | 0.0147 | 0.0636 | 0.2047 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0636 | 0.0636 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0214 | 0.2705 | 0.2198 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0214 | 0.2705 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0147 | 0.0636 | 0.0636 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0148 | 0.065 | 0.065 |
Loa Loa (eye worm) | Notch2 | 0.0147 | 0.0636 | 0.0636 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0148 | 0.065 | 0.065 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 12 nM | Effective concentration determined against melanocortin-4 receptor | ChEMBL. | 15745810 |
IC50 (binding) | = 120 nM | In vitro inhibitory concentration required against melanocortin 4 receptor using [125I]-NDP-MSH as radioligand | ChEMBL. | 15745810 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.