TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 644.267 | Formula: C33H46ClN5O4S
H donors: 1 H acceptors: 4 LogP: 4.38 Rotable bonds: 12
Rule of 5 violations (Lipinski): 2
SMILES: CN1CCCC(CCC1)C(=O)N[C@H](C(=O)N1CCN(CC1)c1ccccc1N(S(=O)(=O)C)CC1CC1)Cc1ccc(cc1)Cl
InChi: 1S/C33H46ClN5O4S/c1-36-17-5-7-27(8-6-18-36)32(40)35-29(23-25-13-15-28(34)16-14-25)33(41)38-21-19-37(20-22-38)30-9-3-4-10-31(30)39(44(2,42)43)24-26-11-12-26/h3-4,9-10,13-16,26-27,29H,5-8,11-12,17-24H2,1-2H3,(H,35,40)/t29-/m1/s1
InChiKey: HSQGZPRAWMUBKQ-GDLZYMKVSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Leishmania major	dihydrofolate reductase-thymidylate synthase	0.032	0.5958	1
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Brugia malayi	Cadherin domain containing protein	0.0147	0.0636	0.0636
Echinococcus multilocularis	neurogenic locus notch protein 4	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Echinococcus multilocularis	slit 2 protein	0.0147	0.0636	0.0636
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Loa Loa (eye worm)	fibroinase	0.0214	0.2705	0.2705
Onchocerca volvulus		0.0147	0.0636	0.2047
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0214	0.2705	0.2705
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Schistosoma mansoni	bifunctional dihydrofolate reductase-thymidylate synthase	0.0227	0.3105	0.3105
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Trypanosoma cruzi	cysteine peptidase, putative	0.0214	0.2705	0.2198
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Onchocerca volvulus	Cathepsin L homolog	0.0214	0.2705	0.8713
Schistosoma mansoni	notch	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Brugia malayi	cathepsin L-like precursor	0.0148	0.065	0.065
Schistosoma mansoni	cathepsin F (C01 family)	0.0214	0.2705	0.2705
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Loa Loa (eye worm)	Notch2	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0148	0.065	0.2094
Echinococcus multilocularis	fibropellin Ia	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Onchocerca volvulus		0.0147	0.0636	0.2047
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Schistosoma mansoni	cathepsin F (C01 family)	0.0214	0.2705	0.2705
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Echinococcus granulosus	delta-like protein 1	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0214	0.2705	0.8713
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0214	0.2705	0.2705
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Schistosoma mansoni	notch	0.0147	0.0636	0.0636
Brugia malayi	Cathepsin L-like precursor	0.0148	0.065	0.065
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	0.032	0.5958	1
Echinococcus multilocularis	protein jagged 2	0.0147	0.0636	0.0636
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Brugia malayi	notch-like transmembrane receptor	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0214	0.2705	1
Brugia malayi	Cathepsin L-like precursor	0.0148	0.065	0.065
Brugia malayi	thymidylate synthase	0.0227	0.3105	0.3105
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Brugia malayi	Muscle positioning protein 4	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Brugia malayi	Calcium binding EGF domain containing protein	0.0147	0.0636	0.0636
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0451	1	1
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Schistosoma mansoni	notch	0.0147	0.0636	0.0636
Echinococcus granulosus	slit 2 protein	0.0147	0.0636	0.0636
Echinococcus granulosus	notch	0.0147	0.0636	0.0636
Echinococcus multilocularis	cathepsin b	0.0451	1	1
Onchocerca volvulus	Slit protein homolog	0.0147	0.0636	0.2047
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Onchocerca volvulus		0.0214	0.2705	0.8713
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Loa Loa (eye worm)	cysteine protease	0.0214	0.2705	0.2705
Echinococcus granulosus	cathepsin l1	0.0214	0.2705	0.2705
Onchocerca volvulus	Cathepsin F homolog	0.0214	0.2705	0.8713
Echinococcus granulosus	cathepsin l1	0.0148	0.065	0.065
Trypanosoma cruzi	cysteine peptidase, putative	0.0214	0.2705	0.2198
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0451	1	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0214	0.2705	0.2705
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Onchocerca volvulus	Cathepsin L homolog	0.0214	0.2705	0.8713
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Echinococcus granulosus	protein jagged 2	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Schistosoma mansoni	cathepsin F (C01 family)	0.0148	0.065	0.065
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	0.032	0.5958	1
Giardia lamblia	Cathepsin B precursor	0.0174	0.146	1
Echinococcus granulosus	neurogenic locus protein delta	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0147	0.0636	0.2047
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Brugia malayi	GCC2 and GCC3 family protein	0.0147	0.0636	0.0636
Echinococcus multilocularis	neurogenic locus protein delta	0.0147	0.0636	0.0636
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Loa Loa (eye worm)	ctsf protein	0.0214	0.2705	0.2705
Schistosoma mansoni	notch	0.0147	0.0636	0.0636
Brugia malayi	Papain family cysteine protease containing protein	0.0214	0.2705	0.2705
Echinococcus granulosus	thymidylate synthase	0.0227	0.3105	0.3105
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2705	0.2705
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	notch protein	0.0147	0.0636	0.0636
Brugia malayi	Transmembrane cell adhesion receptor mua-3 precursor, putative	0.0147	0.0636	0.0636
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0214	0.2705	0.2705
Onchocerca volvulus		0.0214	0.2705	0.8713
Onchocerca volvulus		0.0147	0.0636	0.2047
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0174	0.146	0.0866
Echinococcus multilocularis	neural cadherin	0.0147	0.0636	0.0636
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Echinococcus granulosus	protein jagged 1	0.0147	0.0636	0.0636
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2705	0.2705
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0214	0.2705	0.2705
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2705	0.2705
Schistosoma mansoni	notch	0.0147	0.0636	0.0636
Trypanosoma cruzi	cysteine peptidase, putative	0.0214	0.2705	0.2198
Schistosoma mansoni	notch	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Echinococcus multilocularis	cathepsin b	0.0451	1	1
Brugia malayi	Delta serrate ligand family protein	0.0147	0.0636	0.0636
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2705	0.2705
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0214	0.2705	0.8713
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Schistosoma mansoni	septate junction protein	0.0147	0.0636	0.0636
Echinococcus multilocularis	neurogenic locus notch protein	0.0147	0.0636	0.0636
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	cathepsin B	0.0174	0.146	0.146
Entamoeba histolytica	cysteine proteinase, putative	0.0214	0.2705	1
Echinococcus granulosus	neural cadherin	0.0147	0.0636	0.0636
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0174	0.146	0.146
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Loa Loa (eye worm)	hypothetical protein	0.0214	0.2705	0.2705
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	0.032	0.5958	0.5677
Schistosoma mansoni	Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)]	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0174	0.146	0.394
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0147	0.0636	0.2047
Loa Loa (eye worm)	hypothetical protein	0.0451	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Mycobacterium tuberculosis	Probable thymidylate synthase ThyA (ts) (TSASE)	0.0227	0.3105	0.5
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0451	1	1
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Entamoeba histolytica	cysteine protease, putative	0.0214	0.2705	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0214	0.2705	1
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0148	0.065	0.065
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Toxoplasma gondii	cathepsin CPL	0.0214	0.2705	0.454
Giardia lamblia	Cathepsin B precursor	0.0174	0.146	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.0214	0.2705	0.2705
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Brugia malayi	Calcium binding EGF domain containing protein	0.0147	0.0636	0.0636
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Mycobacterium ulcerans	thymidylate synthase	0.0227	0.3105	0.5
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0214	0.2705	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0214	0.2705	0.2705
Echinococcus granulosus	neurogenic locus notch protein	0.0147	0.0636	0.0636
Echinococcus granulosus	neurogenic locus notch protein	0.0147	0.0636	0.0636
Schistosoma mansoni	cell polarity protein	0.0147	0.0636	0.0636
Onchocerca volvulus	Putative cubilin	0.0147	0.0636	0.2047
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Echinococcus multilocularis	protein jagged 1	0.0147	0.0636	0.0636
Echinococcus granulosus	protein jagged 2	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Echinococcus multilocularis	fat cadherin tumor suppressor	0.0147	0.0636	0.0636
Loa Loa (eye worm)	thymidylate synthase	0.0227	0.3105	0.3105
Onchocerca volvulus	Neurogenic locus notch homolog	0.0147	0.0636	0.2047
Mycobacterium leprae	PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)	0.0227	0.3105	0.5
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768
Echinococcus granulosus	protein jagged 1	0.0147	0.0636	0.0636
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2705	0.2705
Brugia malayi	Cadherin domain containing protein	0.0147	0.0636	0.0636
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Echinococcus multilocularis	cysteine protease	0.0214	0.2705	0.2705
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0451	1	1
Echinococcus multilocularis	thymidylate synthase	0.0227	0.3105	0.3105
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0214	0.2705	1
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	0.032	0.5958	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0214	0.2705	0.2768
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0214	0.2705	0.8713
Echinococcus multilocularis	neurogenic locus protein delta	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Schistosoma mansoni	laminin gamma-3 chain	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0147	0.0636	0.0636
Onchocerca volvulus	Neurogenic locus notch protein homolog	0.0147	0.0636	0.2047
Echinococcus granulosus	fibropellin Ia	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0214	0.2705	0.8713
Echinococcus multilocularis	protein jagged 1	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0227	0.3105	1
Leishmania major	cysteine peptidase A (CPA)	0.0214	0.2705	0.2768
Echinococcus multilocularis	notch	0.0147	0.0636	0.0636
Echinococcus multilocularis	cathepsin L cysteine protease	0.0214	0.2705	0.2705
Toxoplasma gondii	EGF family domain-containing protein	0.0147	0.0636	0.1067
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0148	0.065	0.065
Trypanosoma cruzi	cysteine peptidase, putative	0.0214	0.2705	0.2198
Schistosoma mansoni	slit	0.0147	0.0636	0.0636
Echinococcus multilocularis	cysteine protease	0.0214	0.2705	0.2705
Brugia malayi	Calcium binding EGF domain containing protein	0.0147	0.0636	0.0636
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0148	0.065	0.065
Echinococcus granulosus	neurogenic locus notch protein 4	0.0147	0.0636	0.0636
Echinococcus granulosus	cathepsin b	0.0451	1	1
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	0.032	0.5958	1
Entamoeba histolytica	cysteine proteinase, putative	0.0214	0.2705	1
Trypanosoma cruzi	cruzipain precursor, putative	0.0214	0.2705	0.2198
Brugia malayi	Cathepsin L-like precursor	0.0214	0.2705	0.2705
Brugia malayi	EGF-like domain containing protein	0.0147	0.0636	0.0636
Onchocerca volvulus		0.0214	0.2705	0.8713
Echinococcus granulosus	cathepsin b	0.0451	1	1
Giardia lamblia	Cathepsin B precursor	0.0174	0.146	1
Echinococcus multilocularis	neurogenic locus notch protein	0.0147	0.0636	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0148	0.065	0.065
Schistosoma mansoni	hypothetical protein	0.0147	0.0636	0.0636
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0451	1	1
Toxoplasma gondii	cathepsin B	0.0174	0.146	0.245
Leishmania major	cathepsin L-like protease	0.0214	0.2705	0.2768

Activities

Activity type	Activity value	Assay description	Source	Reference
EC50 (functional)	= 12 nM	Effective concentration determined against melanocortin-4 receptor	ChEMBL.	15745810
IC50 (binding)	= 120 nM	In vitro inhibitory concentration required against melanocortin 4 receptor using [125I]-NDP-MSH as radioligand	ChEMBL.	15745810

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 402463

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 317607