Detailed information for compound 317612

Basic information

Technical information
  • TDR Targets ID: 317612
  • Name: methyl 2-[8-[(2,4-dimethyl-5-oxo-2H-thiophen- 3-yl)oxy]octylsulfanyl]acetate
  • MW: 360.532 | Formula: C17H28O4S2
  • H donors: 0 H acceptors: 2 LogP: 4.31 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)CSCCCCCCCCOC1=C(C)C(=O)SC1C
  • InChi: 1S/C17H28O4S2/c1-13-16(14(2)23-17(13)19)21-10-8-6-4-5-7-9-11-22-12-15(18)20-3/h14H,4-12H2,1-3H3
  • InChiKey: JNRDKJOFWZOOBU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[8-[(2,4-dimethyl-5-oxo-2H-thiophen-3-yl)oxy]octylthio]acetic acid methyl ester
  • methyl 2-[8-[(2,4-dimethyl-5-oxo-2H-thiophen-3-yl)oxy]octylsulfanyl]ethanoate
  • 2-[8-[(5-keto-2,4-dimethyl-2H-thiophen-3-yl)oxy]octylthio]acetic acid methyl ester
  • AIDS227273
  • Acetic acid, [[8-[(2,5-dihydro-2,4-dimethyl-5-oxo-3-thienyl)oxy]octyl]thio]-, methyl ester
  • AIDS-227273

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni myst-related protein 0.0016 0.0007 0.001
Schistosoma mansoni ran 0.0084 0.015 0.0224
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0041 0.006 0.0059
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0018 0.001 0.0109
Echinococcus granulosus lamin 0.0061 0.0103 0.0153
Onchocerca volvulus 0.0021 0.0017 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0021 0.009
Schistosoma mansoni smad 0.0052 0.0082 0.0123
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0005 0.0007
Mycobacterium ulcerans polyketide synthase Pks13 0.0025 0.0026 0.0158
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0136 0.026 0.1677
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.055 0.1136 0.1696
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0013 0.0001 0.0001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0032 0.004 0.0257
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0038 0.009
Echinococcus multilocularis neuropeptide receptor A26 0.1424 0.2985 0.2985
Trichomonas vaginalis ribonuclease H1, putative 0.0044 0.0067 0.0326
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0103 0.0271
Schistosoma mansoni hypothetical protein 0.0041 0.006 0.0089
Onchocerca volvulus 0.0061 0.0103 0.0532
Loa Loa (eye worm) glutaminase 0.024 0.048 0.1276
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0041 0.006 0.0148
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0155 0.0301 0.0449
Brugia malayi Dopamine receptor protein 1 0.0015 0.0005 0.0012
Onchocerca volvulus 0.0034 0.0046 0.0235
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Entamoeba histolytica cysteine proteinase, putative 0.0918 0.1915 1
Onchocerca volvulus Cathepsin L homolog 0.0918 0.1915 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Brugia malayi kap beta 3 protein 0.0022 0.0018 0.0047
Onchocerca volvulus 0.0149 0.0288 0.1501
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni neutral sphingomyelinase 0.0027 0.0031 0.0046
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0133 0.0676
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.008 0.0211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0015 0.0004 0.0006
Loa Loa (eye worm) G protein alpha subunit 3 0.0024 0.0023 0.0058
Echinococcus granulosus mucolipin 3 0.0044 0.0065 0.0097
Trypanosoma brucei pyruvate kinase 1, putative 0.0025 0.0026 0.0115
Entamoeba histolytica hypothetical protein 0.0184 0.0363 0.1877
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0041 0.006 0.0059
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0041 0.006 0.029
Loa Loa (eye worm) pyruvate kinase-PB 0.0018 0.001 0.0025
Echinococcus multilocularis neutral alpha glucosidase AB 0.0057 0.0094 0.0094
Onchocerca volvulus 0.0015 0.0005 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0209 0.0415 0.2152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.0415 0.2152
Trypanosoma cruzi cysteine peptidase, putative 0.0918 0.1915 0.5096
Brugia malayi Melatonin receptor type 1A 0.0015 0.0005 0.0012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0076 0.0133 0.0696
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0005 0.0012
Echinococcus multilocularis microtubule associated protein 2 0.1007 0.2103 0.2102
Trypanosoma cruzi cysteine peptidase, putative 0.0287 0.0581 0.1538
Onchocerca volvulus 0.0032 0.004 0.0204
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Plasmodium falciparum serine repeat antigen 9 0.0209 0.0415 0.2168
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Brugia malayi Cathepsin L-like precursor 0.0631 0.1307 0.3481
Entamoeba histolytica cysteine proteinase, putative 0.0497 0.1024 0.5334
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0084 0.015 0.0389
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0091 0.3403
Leishmania major pantothenate kinase subunit, putative 0.0028 0.0032 0.0147
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0133 0.0676
Schistosoma mansoni synaptojanin 0.0027 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0918 0.1915 0.5096
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0018 0.001 0.0109
Loa Loa (eye worm) hypothetical protein 0.0294 0.0595 0.1584
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0104
Loa Loa (eye worm) hypothetical protein 0.0631 0.1307 0.3481
Loa Loa (eye worm) hypothetical protein 0.0106 0.0197 0.0523
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0041 0.006 0.029
Loa Loa (eye worm) hypothetical protein 0.0159 0.0309 0.082
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0076 0.0133 0.0676
Leishmania major hypothetical protein, conserved 0.0032 0.004 0.0186
Schistosoma mansoni amine GPCR 0.016 0.0311 0.0464
Loa Loa (eye worm) hypothetical protein 0.0431 0.0883 0.2352
Schistosoma mansoni disulfide oxidoreductase 0.0015 0.0004 0.0006
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0031 0.008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0431 0.0883 0.2352
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0024 0.0023 0.0034
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0032 0.004 0.0257
Schistosoma mansoni aldehyde dehydrogenase 0.0745 0.1549 0.2315
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0013 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Leishmania major aldehyde dehydrogenase, putative 0.0041 0.006 0.029
Brugia malayi MH1 domain containing protein 0.0052 0.0082 0.0217
Loa Loa (eye worm) hypothetical protein 0.0155 0.0301 0.08
Trypanosoma brucei ribonuclease H1 0.0044 0.0067 0.0326
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0209 0.0415 0.2868
Echinococcus multilocularis muscleblind protein 0.011 0.0205 0.0205
Schistosoma mansoni high-affinity choline transporter 0.072 0.1495 0.2233
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0057 0.0094 0.0469
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0084 0.015 0.0782
Mycobacterium tuberculosis Probable reductase 0.0369 0.0752 0.4855
Schistosoma mansoni SET domain protein 0.0017 0.0008 0.0011
Plasmodium vivax vivapain-2 0.0918 0.1915 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.008 0.0119
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0084 0.015 0.0782
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0011 0.0073
Brugia malayi G-protein coupled receptor 0.0015 0.0005 0.0012
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0041 0.006 0.0089
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0024 0.0023 0.0058
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0056 0.0091 0.0475
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0023 0.0097
Echinococcus multilocularis mitogen activated protein kinase 3 0.0076 0.0133 0.0133
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0369 0.0752 0.8962
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0024 0.0023 0.0058
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Trypanosoma cruzi trypanothione reductase, putative 0.0162 0.0314 0.0827
Brugia malayi neuropeptide F receptor 0.0015 0.0005 0.0012
Brugia malayi Cathepsin L-like precursor 0.0918 0.1915 0.51
Onchocerca volvulus 0.0918 0.1915 1
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0209 0.0415 0.2168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0094 0.0469
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0209 0.0415 0.1105
Echinococcus multilocularis somatostatin receptor 0.0015 0.0005 0.0005
Plasmodium vivax exodeoxyribonuclease III, putative 0.0027 0.0031 0.0159
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0013 0.0001 0.0001
Mycobacterium ulcerans NADH dehydrogenase 0.0015 0.0004 0.0019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0209 0.0415 0.1105
Schistosoma mansoni hypothetical protein 0.0136 0.0261 0.039
Loa Loa (eye worm) mucolipin 1 0.0044 0.0065 0.0171
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0209 0.0415 0.062
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Trypanosoma brucei importin beta-1 subunit, putative 0.0114 0.0214 0.1096
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0209 0.0415 0.2152
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.008 0.0211
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0005 0.0005
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0029 0.0076
Brugia malayi Pre-SET motif family protein 0.0117 0.022 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Brugia malayi CCR4 0.0027 0.0031 0.008
Schistosoma mansoni histamine h1 receptor 0.0015 0.0005 0.0007
Plasmodium vivax vivapain-3 0.0497 0.1024 0.5343
Echinococcus granulosus sodium:glucose cotransporter 0.0079 0.0141 0.021
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0005 0.0007
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0027 0.0031 0.0139
Brugia malayi glutaminase DH11.1 0.024 0.048 0.1276
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0023 0.0035
Loa Loa (eye worm) beta-lactamase 0.0032 0.004 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Plasmodium falciparum serine repeat antigen 7 0.0209 0.0415 0.2168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0021 0.009
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0004 0.0019
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Entamoeba histolytica hypothetical protein 0.0209 0.0415 0.2152
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Brugia malayi RNase H family protein 0.0044 0.0067 0.0175
Brugia malayi Cathepsin L-like precursor 0.0631 0.1307 0.3481
Trypanosoma cruzi cruzipain precursor, putative 0.0918 0.1915 0.5096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Plasmodium vivax transportin, putative 0.0022 0.0018 0.0095
Brugia malayi RNase H family protein 0.0044 0.0067 0.0175
Brugia malayi RNA, U transporter 1 0.0324 0.0658 0.175
Onchocerca volvulus Huntingtin homolog 0.0257 0.0517 0.2695
Plasmodium vivax acyl-CoA synthetase, putative 0.0014 0.0002 0.0007
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0029 0.0029
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0209 0.0415 0.2868
Brugia malayi nuclear receptor NHR-88 0.0024 0.0023 0.006
Onchocerca volvulus Cathepsin L homolog 0.0209 0.0415 0.2166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0918 0.1915 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0067 0.0114 0.0293
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0091 0.0232
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0027 0.0031 0.003
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0031 0.008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.055 0.1136 0.3023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0056 0.0091 0.0136
Brugia malayi beta-lactamase family protein 0.0032 0.004 0.0104
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0038 0.0054 0.0054
Entamoeba histolytica cysteine proteinase, putative 0.0918 0.1915 1
Loa Loa (eye worm) importin-beta domain-containing protein 0.0022 0.0018 0.0047
Onchocerca volvulus 0.0024 0.0023 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Trichomonas vaginalis esterase, putative 0.0032 0.004 0.0186
Brugia malayi sulfakinin receptor protein 0.0015 0.0005 0.0012
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.011 0.0205 0.0544
Loa Loa (eye worm) hypothetical protein 0.0209 0.0415 0.1105
Echinococcus multilocularis pyruvate kinase 0.0025 0.0026 0.0026
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0005 0.0005
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0056 0.0091 0.0136
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0005 0.0012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Trichomonas vaginalis alpha-glucosidase, putative 0.0021 0.0018 0.0071
Brugia malayi Aldehyde dehydrogenase protein 4 0.0041 0.006 0.0157
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0202 0.0401 0.2586
Trypanosoma brucei ISWI complex protein 0.0034 0.0045 0.0216
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0257 0.0517 0.1375
Schistosoma mansoni hypothetical protein 0.0136 0.0261 0.039
Trichomonas vaginalis mercuric reductase, putative 0.0056 0.0091 0.0455
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0084 0.015 0.0389
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0017 0.0008 0.002
Brugia malayi Dopamine receptor protein 2 0.0015 0.0005 0.0012
Plasmodium vivax thioredoxin reductase, putative 0.0162 0.0314 0.1641
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.0134
Giardia lamblia Cathepsin L precursor 0.0209 0.0415 0.2868
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0015 0.0004 0.0009
Echinococcus granulosus glycine receptor subunit alpha 1 0.0013 0.0001 0.0001
Trypanosoma brucei cysteine peptidase C (CPC) 0.0697 0.1448 0.7556
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0209 0.0415 0.062
Schistosoma mansoni hypothetical protein 0.0046 0.0071 0.0105
Brugia malayi beta-lactamase family protein 0.0032 0.004 0.0104
Echinococcus multilocularis cathepsin b 0.1788 0.3754 0.3754
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0041 0.006 0.0376
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.006 0.0101 0.015
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0023 0.006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0026 0.0068
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0023 0.0022 0.011
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0004 0.0006
Onchocerca volvulus 0.0015 0.0005 0.0023
Giardia lamblia Cathepsin B precursor 0.0697 0.1448 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0048 0.0074 0.0367
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Onchocerca volvulus 0.0015 0.0005 0.0023
Echinococcus granulosus microtubule associated protein 2 0.1007 0.2103 0.3141
Loa Loa (eye worm) hypothetical protein 0.006 0.0101 0.0266
Entamoeba histolytica acyl-coA synthetase, putative 0.0018 0.0011 0.0037
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Onchocerca volvulus 0.0015 0.0005 0.0023
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0041 0.006 0.0695
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0084 0.0151 0.0399
Onchocerca volvulus 0.006 0.0101 0.0522
Onchocerca volvulus 0.0015 0.0005 0.0023
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0056 0.0091 0.0475
Giardia lamblia Hypothetical protein 0.0209 0.0415 0.2868
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0136 0.026 0.1355
Schistosoma mansoni opsin-like receptor 0.0015 0.0005 0.0007
Brugia malayi Coelomocyte uptake defective protein 5 0.0044 0.0065 0.0171
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0005 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0011 0.0028
Brugia malayi RNase H family protein 0.0044 0.0067 0.0175
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Plasmodium falciparum importin beta, putative 0.0114 0.0214 0.1114
Schistosoma mansoni zinc finger protein 0.0054 0.0088 0.0131
Schistosoma mansoni alpha glucosidase 0.0057 0.0094 0.014
Brugia malayi RE15519p 0.0015 0.0005 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0005 0.0007
Onchocerca volvulus 0.0027 0.0031 0.0156
Entamoeba histolytica acetyltransferase, GNAT family 0.005 0.0079 0.0393
Giardia lamblia Cathepsin B precursor 0.0209 0.0415 0.2868
Echinococcus granulosus sodium:myo inositol cotransporter 0.0079 0.0141 0.021
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0079 0.0141 0.014
Onchocerca volvulus 0.0032 0.004 0.0204
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0038 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Schistosoma mansoni transcription factor LCR-F1 0.0184 0.0363 0.0542
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0052 0.0082 0.0123
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.0035 0.0035
Leishmania major glycosyl hydrolase-like protein 0.0021 0.0018 0.0071
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0022 0.0056
Brugia malayi MH1 domain containing protein 0.0029 0.0033 0.0087
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.006 0.0089
Loa Loa (eye worm) TAR-binding protein 0.0345 0.0703 0.187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0018 0.0011 0.0065
Plasmodium vivax serine-repeat antigen (SERA) 0.0209 0.0415 0.2168
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0631 0.1307 0.6818
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0133 0.0676
Echinococcus multilocularis survival motor neuron protein 1 0.0412 0.0844 0.0844
Loa Loa (eye worm) MH1 domain-containing protein 0.0052 0.0082 0.0217
Schistosoma mansoni sodium/chloride dependent transporter 0.0038 0.0053 0.0078
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.008 0.0119
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0036 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0056
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0005 0.0012
Mycobacterium ulcerans hypothetical protein 0.0032 0.004 0.0249
Loa Loa (eye worm) glutaminase 2 0.024 0.048 0.1276
Schistosoma mansoni smad1 5 8 and 0.0052 0.0082 0.0123
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0038 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0005 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.008 0.0211
Echinococcus multilocularis pyruvate kinase 0.0025 0.0026 0.0026
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.006 0.0089
Toxoplasma gondii LsmAD domain-containing protein 0.0067 0.0114 0.0594
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0117 0.022 0.022
Mycobacterium tuberculosis Probable oxidoreductase 0.041 0.0839 0.5416
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.008 0.0414
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0911 0.19 0.2839
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0041 0.006 0.0384
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0057 0.0094 0.0469
Leishmania major alpha glucosidase II subunit, putative 0.0057 0.0094 0.0469
Toxoplasma gondii thioredoxin reductase 0.0162 0.0314 0.1641
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0023 0.0035
Plasmodium vivax histone acetyltransferase GCN5, putative 0.006 0.01 0.0522
Trypanosoma cruzi ISWI complex protein 0.0034 0.0045 0.011
Plasmodium falciparum thioredoxin reductase 0.0162 0.0314 0.1641
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0084 0.015 0.1035
Echinococcus multilocularis cathepsin L cysteine protease 0.0918 0.1915 0.1915
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0017 0.0044
Trypanosoma brucei RNA helicase, putative 0.0166 0.0325 0.1676
Loa Loa (eye worm) hypothetical protein 0.0257 0.0517 0.1375
Trypanosoma cruzi ISWI complex protein 0.0034 0.0045 0.011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0056 0.0091 0.0455
Brugia malayi Glycosyl hydrolases family 31 protein 0.0021 0.0018 0.0045
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0023 0.0023
Entamoeba histolytica HEAT repeat domain containing protein 0.0022 0.0018 0.0074
Leishmania major hypothetical protein, conserved 0.0022 0.0018 0.0074
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1788 0.3754 1
Schistosoma mansoni hypothetical protein 0.0015 0.0004 0.0006
Trypanosoma brucei unspecified product 0.0048 0.0075 0.0368
Echinococcus granulosus mitogen activated protein kinase 3 0.0076 0.0133 0.0199
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0015 0.0004 0.0021
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0005 0.0007
Schistosoma mansoni nuclear receptor 0.0024 0.0023 0.0035
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0041 0.006 0.0384
Leishmania major pyruvate kinase 0.0025 0.0026 0.0115
Trichomonas vaginalis D-aminoacylase, putative 0.0032 0.004 0.0186
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0041 0.006 0.0695
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0013 0.0001 0.0001
Echinococcus granulosus cathepsin l1 0.0631 0.1307 0.1953
Onchocerca volvulus 0.0631 0.1307 0.6824
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0022 0.0022
Echinococcus granulosus cpg binding protein 0.0112 0.0209 0.0312
Plasmodium falciparum ataxin-2 like protein, putative 0.0067 0.0114 0.0594
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0041 0.006 0.029
Schistosoma mansoni cpg binding protein 0.0112 0.0209 0.0312
Brugia malayi Cathepsin L-like precursor 0.0918 0.1915 0.51
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0084 0.015 0.0398
Giardia lamblia Cathepsin B precursor 0.0697 0.1448 1
Trypanosoma brucei pyruvate kinase 1 0.0025 0.0026 0.0115
Brugia malayi MH2 domain containing protein 0.0052 0.0082 0.0217
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0024 0.0023 0.0058
Echinococcus granulosus transcription factor Dp 1 0.0028 0.0032 0.0047
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0005 0.0007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0013 0.0018
Loa Loa (eye worm) acetyltransferase 0.0192 0.0379 0.1008
Schistosoma mansoni ap endonuclease 0.0136 0.026 0.0388
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0011 0.012
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0037 0.0051 0.0134
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus multilocularis cysteine protease 0.0918 0.1915 0.1915
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.008 0.008
Echinococcus granulosus nAChR subunit 0.0013 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi cysteine protease, putative 0.0497 0.1024 0.2718
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.006 0.0089
Echinococcus granulosus zinc finger protein 0.0054 0.0088 0.0131
Onchocerca volvulus 0.0015 0.0005 0.0023
Echinococcus multilocularis lysosomal alpha glucosidase 0.0258 0.0518 0.0518
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0023 0.006
Schistosoma mansoni nuclear receptor 0.0024 0.0023 0.0035
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0258 0.0518 0.1378
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.008 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.0415 0.2152
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Schistosoma mansoni cpg binding protein 0.0112 0.0209 0.0312
Loa Loa (eye worm) hypothetical protein 0.072 0.1495 0.398
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0041 0.006 0.0059
Schistosoma mansoni zinc finger protein 0.0034 0.0045 0.0068
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0071
Brugia malayi CXXC zinc finger family protein 0.0102 0.0188 0.0498
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.008 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.008 0.0211
Loa Loa (eye worm) hypothetical protein 0.0096 0.0176 0.0467
Brugia malayi Papain family cysteine protease containing protein 0.0209 0.0415 0.1105
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0209 0.0415 0.2152
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0015 0.0004 0.0004
Plasmodium vivax pyruvate kinase, putative 0.0025 0.0026 0.0136
Mycobacterium tuberculosis Probable dehydrogenase 0.0369 0.0752 0.4855
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Brugia malayi hypothetical protein 0.0067 0.0114 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0497 0.1024 0.5334
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0015 0.0004 0.0027
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0041 0.006 0.0376
Mycobacterium ulcerans pyruvate kinase 0.0025 0.0026 0.0162
Brugia malayi TAR-binding protein 0.0345 0.0703 0.187
Trichomonas vaginalis glutaminase, putative 0.024 0.048 0.2487
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0015 0.0004 0.0019
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0015 0.0004 0.0009
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0084 0.015 0.0398
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Leishmania major importin beta-1 subunit, putative 0.0092 0.0168 0.0858
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0029 0.0044
Echinococcus granulosus sodium and chloride dependent glycine 0.0037 0.0051 0.0076
Giardia lamblia Cathepsin L-like protease 0.0209 0.0415 0.2868
Loa Loa (eye worm) hypothetical protein 0.0209 0.0415 0.1105
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0023 0.006
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Schistosoma mansoni ran 0.0084 0.015 0.0224
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0005 0.0007
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0094 0.0239
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0024 0.0023 0.0097
Echinococcus multilocularis serotonin receptor 0.0015 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Mycobacterium tuberculosis Probable exported protein 0.0027 0.0031 0.0198
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0038 0.0056
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0136 0.026 0.026
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.0035 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.008 0.0211
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0076 0.0133 0.0676
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0024 0.0023 0.0097
Leishmania major hypothetical protein, conserved 0.0027 0.0031 0.0139
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0041 0.006 0.0384
Echinococcus multilocularis synaptojanin 1 0.0027 0.0031 0.003
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0005 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0032 0.004 0.0206
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0048 0.0075 0.0368
Echinococcus multilocularis thyroid hormone receptor alpha 0.0143 0.0275 0.0275
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0094 0.0469
Leishmania major hypothetical protein, conserved 0.0067 0.0114 0.0575
Brugia malayi ecdysteroid receptor 0.0051 0.008 0.0211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.008 0.0119
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0031 0.008
Schistosoma mansoni tar DNA-binding protein 0.0345 0.0703 0.1049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.008 0.0211
Mycobacterium tuberculosis Probable thioesterase TesA 0.0014 0.0002 0.0015
Brugia malayi PHD-finger family protein 0.0066 0.0113 0.0299
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0005 0.0005
Schistosoma mansoni Smad4 0.0052 0.0082 0.0123
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0022 0.0032
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0027 0.0031 0.0139
Schistosoma mansoni glutaminase 0.024 0.048 0.0716
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0041 0.006 0.0148
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.0415 0.2152
Trypanosoma cruzi cysteine proteinase, putative 0.0497 0.1024 0.2718
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0007
Treponema pallidum exodeoxyribonuclease (exoA) 0.0136 0.026 1
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0041 0.006 0.029
Schistosoma mansoni pyruvate kinase 0.0025 0.0026 0.0039
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0038 0.0244
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0117 0.022 0.0328
Onchocerca volvulus 0.0027 0.0031 0.0156
Echinococcus multilocularis lysosomal alpha glucosidase 0.0258 0.0518 0.0518
Schistosoma mansoni ap endonuclease 0.0136 0.026 0.0388
Schistosoma mansoni smad1 5 8 and 0.0052 0.0082 0.0123
Brugia malayi hypothetical protein 0.0257 0.0517 0.1375
Plasmodium falciparum serine repeat antigen 5 0.0209 0.0415 0.2168
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus granulosus glycine receptor subunit alpha 1 0.0013 0.0001 0.0001
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0209 0.0415 0.062
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0023 0.0035
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0184 0.0363 0.0542
Leishmania major hypothetical protein, conserved 0.0034 0.0045 0.0216
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0041 0.006 0.029
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0056 0.0091 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.0415 0.2152
Schistosoma mansoni tar DNA-binding protein 0.0345 0.0703 0.1049
Loa Loa (eye worm) hypothetical protein 0.0209 0.0415 0.1105
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0024 0.0023 0.0058
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.008 0.0119
Trichomonas vaginalis penicillin-binding protein, putative 0.0032 0.004 0.0186
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0056 0.0091 0.0581
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis Smad4 0.0052 0.0082 0.0082
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0243 0.0488 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.0415 0.2152
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0018 0.001 0.0067
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0038 0.0196
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0014 0.0002 0.001
Trypanosoma cruzi cysteine peptidase, putative 0.0918 0.1915 0.5096
Onchocerca volvulus 0.0918 0.1915 1
Brugia malayi ORL1-like opioid receptor 0.0015 0.0005 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0067 0.0114 0.0293
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0209 0.0415 0.2168
Trypanosoma cruzi major cysteine proteinase, putative 0.0209 0.0415 0.1097
Echinococcus granulosus importin 5 0.0022 0.0018 0.0027
Trichomonas vaginalis sucrase-isomaltase, putative 0.0057 0.0094 0.0469
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0031 0.0071
Echinococcus granulosus smad 0.0052 0.0082 0.0123
Trichomonas vaginalis CMGC family protein kinase 0.0076 0.0133 0.0676
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0369 0.0752 0.4855
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0094 0.0469
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.0031 0.0139
Echinococcus multilocularis lamin dm0 0.0061 0.0103 0.0102
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0004 0.0021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0017 0.0008 0.0053
Mycobacterium tuberculosis Probable lipase LipE 0.0032 0.004 0.0257
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0057 0.0094 0.0488
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0021 0.009
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0041 0.006 0.0157
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0079 0.0141 0.021
Onchocerca volvulus Huntingtin homolog 0.0257 0.0517 0.2695
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.008 0.008
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0031 0.0159
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0136 0.0261 0.0693
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0038 0.0038
Entamoeba histolytica acyl-CoA synthetase, putative 0.002 0.0015 0.0056
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0004 0.0006
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0018 0.0095
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0076 0.0133 0.0345
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0023 0.0035
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0005 0.0005
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0144 0.0278 0.0415
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0021 0.0018 0.0071
Onchocerca volvulus 0.0015 0.0005 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0631 0.1307 0.6818
Plasmodium falciparum glutathione reductase 0.0056 0.0091 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.006 0.0101 0.01
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0139
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0015 0.0004 0.0019
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0024 0.0023 0.0034
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0023 0.0035
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0014 0.0002 0.0002
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0092 0.0168 0.025
Loa Loa (eye worm) transcription factor SMAD2 0.076 0.1581 0.4211
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0013 0.0001 0.0001
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0041 0.006 0.0148
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Echinococcus granulosus cathepsin b 0.1788 0.3754 0.5609
Brugia malayi Cathepsin L-like precursor 0.0287 0.0581 0.1545
Plasmodium falciparum cysteine proteinase falcipain 1 0.0497 0.1024 0.5343
Brugia malayi cathepsin L precursor 0.0209 0.0415 0.1105
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Mycobacterium tuberculosis Conserved protein 0.0032 0.004 0.0257
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0035 0.0035
Echinococcus multilocularis transportin 1 0.0022 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.0092
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0209 0.0415 0.2152
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0031 0.008
Brugia malayi Sodium:solute symporter family protein 0.0079 0.0141 0.0373
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.006 0.01 0.0522
Schistosoma mansoni biogenic amine receptor 0.0015 0.0005 0.0007
Echinococcus granulosus glycine receptor subunit alpha 1 0.0013 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0136 0.026 0.1337
Echinococcus granulosus somatostatin receptor 0.0015 0.0005 0.0007
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0027 0.0031 0.0046
Echinococcus multilocularis tar DNA binding protein 0.0345 0.0703 0.0702
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0071
Schistosoma mansoni cathepsin F (C01 family) 0.0918 0.1915 0.2861
Onchocerca volvulus 0.0918 0.1915 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0032 0.004 0.0104
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0918 0.1915 0.1915
Schistosoma mansoni alpha-glucosidase 0.0222 0.0442 0.066
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0041 0.006 0.0089
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0031 0.0159
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0076 0.0133 0.0345
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0021 0.0018 0.0036
Schistosoma mansoni tar DNA-binding protein 0.0345 0.0703 0.1049
Echinococcus granulosus traf and tnf receptor associated protein 0.0027 0.0031 0.0046
Mycobacterium ulcerans hypothetical protein 0.0018 0.0011 0.0065
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0024 0.0023 0.0058
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0048 0.0074 0.0187
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0015 0.0004 0.0035
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0056 0.0091 0.0475
Entamoeba histolytica cysteine protease, putative 0.0918 0.1915 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Plasmodium vivax ferrodoxin reductase, putative 0.0015 0.0004 0.0021
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0042 0.0111
Echinococcus multilocularis translational activator gcn1 0.0022 0.0018 0.0018
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0209 0.0415 0.1105
Brugia malayi RNA recognition motif domain containing protein 0.0345 0.0703 0.187
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0027 0.0031 0.0139
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0031 0.0139
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0041 0.006 0.0376
Giardia lamblia Cathepsin L precursor 0.0209 0.0415 0.2868
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0209 0.0415 0.062
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0801 0.1668 0.4441
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.008 0.0211
Onchocerca volvulus 0.0918 0.1915 1
Echinococcus multilocularis cpg binding protein 0.0112 0.0209 0.0209
Brugia malayi RNA binding protein 0.0345 0.0703 0.187
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.008 0.0119
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Mycobacterium ulcerans Type I modular polyketide synthase 0.0017 0.0008 0.0045
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0005 0.0007
Echinococcus granulosus FTZ F1 alpha 0.0051 0.008 0.0119
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0038 0.0056
Giardia lamblia NADH oxidase lateral transfer candidate 0.0056 0.0091 0.0628
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0497 0.1024 0.5334
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0092 0.0168 0.0858
Trichomonas vaginalis hypothetical protein 0.0022 0.0018 0.0074
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0076 0.0133 0.0345
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Echinococcus multilocularis cathepsin L 0.0209 0.0415 0.0415
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0005 0.0005
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0041 0.006 0.031
Schistosoma mansoni Smad4 0.0023 0.0022 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0075 0.0368
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0013 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0631 0.1307 0.6818
Toxoplasma gondii type I fatty acid synthase, putative 0.0019 0.0012 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0133 0.0199
Echinococcus granulosus solute carrier family 5 0.0079 0.0141 0.021
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0035 0.0052
Echinococcus granulosus snurportin 1 0.1216 0.2544 0.3801
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0005 0.0007
Echinococcus multilocularis cysteine protease 0.0918 0.1915 0.1915
Trypanosoma brucei ingi protein (ORF1) 0.0048 0.0075 0.0368
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Echinococcus granulosus Smad4 0.0052 0.0082 0.0123
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0092 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0015 0.0004 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.055 0.1136 0.1696
Brugia malayi fibroinase precursor 0.0209 0.0415 0.1105
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.0031 0.0159
Echinococcus granulosus sex peptide receptor 0.0015 0.0005 0.0007
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0497 0.1024 0.1529
Echinococcus multilocularis deoxyribonuclease 1 2 0.0027 0.0031 0.003
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0094 0.0469
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0041 0.006 0.2165
Echinococcus granulosus tar DNA binding protein 0.0345 0.0703 0.1049
Schistosoma mansoni pyruvate kinase 0.0025 0.0026 0.0039
Loa Loa (eye worm) fibroinase 0.0918 0.1915 0.51
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0041 0.006 0.031
Brugia malayi Pyruvate kinase, muscle isozyme 0.0025 0.0026 0.0068
Leishmania major cysteine peptidase A (CPA) 0.0918 0.1915 1
Schistosoma mansoni bromodomain containing protein 0.002 0.0015 0.0022
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0013 0.0001 0.0001
Giardia lamblia Inositol 5-phosphatase 4 0.0027 0.0031 0.0211
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0091 0.0232
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0007
Brugia malayi MH2 domain containing protein 0.0052 0.0082 0.0217
Giardia lamblia Cathepsin B precursor 0.0209 0.0415 0.2868
Trypanosoma brucei ingi protein (ORF1) 0.0048 0.0075 0.0368
Brugia malayi Papain family cysteine protease containing protein 0.0497 0.1024 0.2725
Brugia malayi cathepsin B-like cysteine proteinase 0.1788 0.3754 1
Echinococcus multilocularis smad 0.0052 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0013 0.0001 0.0001
Giardia lamblia Cathepsin B precursor 0.0209 0.0415 0.2868
Schistosoma mansoni thyroid hormone receptor 0.0143 0.0275 0.041
Brugia malayi neuropeptide F receptor 0.0015 0.0005 0.0012
Entamoeba histolytica G protein alpha subunit, putative 0.0024 0.0023 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0092 0.0168 0.0858
Echinococcus granulosus histone acetyltransferase KAT2B 0.0181 0.0357 0.0533
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.055 0.1136 0.3023
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.003 0.0035 0.0035
Entamoeba histolytica cysteine proteinase, putative 0.0497 0.1024 0.5334
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0209 0.0415 0.2168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0021 0.009
Loa Loa (eye worm) hypothetical protein 0.0114 0.0214 0.0567
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0086
Brugia malayi Cathepsin L-like precursor 0.0918 0.1915 0.51
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.008 0.0211
Schistosoma mansoni hypothetical protein 0.0294 0.0595 0.0889
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0022 0.0056
Loa Loa (eye worm) hypothetical protein 0.0918 0.1915 0.51
Plasmodium vivax SET domain containing protein 0.0016 0.0007 0.0037
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0005 0.0012
Onchocerca volvulus 0.0032 0.004 0.0204
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0079 0.0141 0.014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.008 0.0119
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.008 0.0119
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0058
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0209 0.0415 0.062
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0007
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0041 0.006 0.0695
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0011 0.0065
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0017 0.0008 0.0053
Entamoeba histolytica cysteine proteinase 1, putative 0.0497 0.1024 0.5334
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0232
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0021 0.0018 0.0071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0023 0.0035
Schistosoma mansoni nocturnin 0.0027 0.0031 0.0046
Plasmodium falciparum zinc finger protein, putative 0.0016 0.0007 0.0036
Schistosoma mansoni lamin 0.0061 0.0103 0.0153
Brugia malayi cathepsin Z-like cysteine proteinase 0.0209 0.0415 0.1105
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Onchocerca volvulus 0.0918 0.1915 1
Loa Loa (eye worm) hypothetical protein 0.006 0.01 0.0265
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Giardia lamblia Cathepsin L precursor 0.0209 0.0415 0.2868
Trichomonas vaginalis set domain proteins, putative 0.0912 0.1901 0.9927
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0005 0.0007
Brugia malayi Bromodomain containing protein 0.0179 0.0351 0.0933
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0017 0.0009 0.0801
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0005 0.0007
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0005 0.0012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Mycobacterium ulcerans Type I modular polyketide synthase 0.0017 0.0008 0.0045
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0136 0.026 0.0388
Schistosoma mansoni importin beta-1 0.0114 0.0214 0.0319
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0918 0.1915 0.1915
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0017 0.0009 0.0048
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0041 0.006 0.029
Trichomonas vaginalis D-aminoacylase, putative 0.0032 0.004 0.0186
Toxoplasma gondii cathepsin CPL 0.0918 0.1915 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0048 0.0074 0.0196
Schistosoma mansoni Smad4 0.0023 0.0022 0.0032
Mycobacterium ulcerans polyketide synthase 0.0017 0.0008 0.0045
Plasmodium vivax unspecified product 0.0209 0.0415 0.2168
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0005 0.0005
Brugia malayi nuclear receptor NHR-67 0.0024 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0086 0.0155 0.0411
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0056 0.0091 0.0581
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0232
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0025 0.0026 0.0166
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0005 0.0007
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0048 0.0074 0.0111
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0005 0.0005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.003 0.0035 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0697 0.1448 0.2163
Mycobacterium ulcerans aldehyde dehydrogenase 0.0745 0.1549 1
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0041 0.006 0.0148
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0104
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0024 0.0023 0.0022
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0056 0.0091 0.0455
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.006 0.01 0.0502
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0076 0.0133 0.0353
Plasmodium falciparum ataxin-2 like protein, putative 0.0067 0.0114 0.0594
Echinococcus granulosus neutral sphingomyelinase 0.0027 0.0031 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Echinococcus granulosus neuropeptide receptor 0.0015 0.0005 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0011 0.0065
Brugia malayi Serotonin receptor 0.0015 0.0005 0.0012
Brugia malayi latrophilin 2 splice variant baaae 0.0294 0.0595 0.1584
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.008 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Onchocerca volvulus 0.0015 0.0004 0.0018
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0005 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Echinococcus granulosus cathepsin l1 0.0918 0.1915 0.2861
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0209 0.0415 0.2168
Giardia lamblia Cysteine protease 0.0209 0.0415 0.2868
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Brugia malayi MH2 domain containing protein 0.0023 0.0022 0.0056
Trichomonas vaginalis alpha-glucosidase, putative 0.0021 0.0018 0.0071
Schistosoma mansoni hypothetical protein 0.0092 0.0168 0.025
Trypanosoma cruzi importin beta-1 subunit, putative 0.0092 0.0168 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0918 0.1915 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0918 0.1915 0.1915
Brugia malayi isocitrate dehydrogenase 0.0031 0.0038 0.0099
Plasmodium falciparum transportin 0.0022 0.0018 0.0095
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0027 0.0031 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0155 0.0301 0.0301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.0415 0.2152
Loa Loa (eye worm) histone methyltransferase 0.0036 0.0048 0.0126
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0005 0.0005
Brugia malayi glutathione reductase 0.0162 0.0314 0.0836
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0041 0.006 0.0089
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0001 0.0001
Brugia malayi GnHR receptor homolog 0.0015 0.0005 0.0012
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0697 0.1448 0.385
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0027 0.0031 0.0139
Leishmania major GTP-binding protein, putative 0.0084 0.015 0.0763
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Trypanosoma cruzi cysteine peptidase, putative 0.0918 0.1915 0.5096
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.0031 0.0071
Giardia lamblia Kinase, CMGC MAPK 0.0076 0.0133 0.092
Mycobacterium ulcerans aldehyde dehydrogenase 0.0745 0.1549 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Plasmodium falciparum serine repeat antigen 4 0.0209 0.0415 0.2168
Schistosoma mansoni mucolipin 0.0044 0.0065 0.0097
Echinococcus granulosus mothers against decapentaplegic 5 0.0052 0.0082 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0209 0.0415 0.2152
Echinococcus granulosus mitogen activated protein kinase 0.0076 0.0133 0.0199
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0057 0.0094 0.0248
Echinococcus granulosus cysteine protease 0.0497 0.1024 0.1529
Trichomonas vaginalis conserved hypothetical protein 0.0209 0.0415 0.2152
Onchocerca volvulus Cathepsin L homolog 0.0918 0.1915 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0021 0.0018 0.0071
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0041 0.006 0.0384
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0024 0.0023 0.0097
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.0031 0.0139
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0041 0.006 0.029
Echinococcus multilocularis mucolipin 3 0.0044 0.0065 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.008 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.008 0.0211
Trypanosoma cruzi major cysteine proteinase, putative 0.0209 0.0415 0.1097
Loa Loa (eye worm) hypothetical protein 0.0287 0.0581 0.1545
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0139
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1788 0.3754 0.5609
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0918 0.1915 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0102 0.0188 0.0498
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0009 0.0044
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0007
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0023 0.0097
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0139
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0024 0.0023 0.0034
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0011 0.0037
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0005 0.0005
Schistosoma mansoni hypothetical protein 0.0136 0.0261 0.039
Onchocerca volvulus 0.0084 0.0151 0.0782
Trichomonas vaginalis maltase-glucoamylase, putative 0.0021 0.0018 0.0071
Echinococcus granulosus neutral alpha glucosidase AB 0.0057 0.0094 0.014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0232
Brugia malayi hypothetical protein 0.0024 0.0023 0.006
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.008 0.008
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0027 0.0031 0.0159
Echinococcus multilocularis mitogen activated protein kinase 0.0076 0.0133 0.0133
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0032 0.004 0.0059
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0091 0.0455
Brugia malayi MH1 domain containing protein 0.0029 0.0033 0.0087
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0041 0.006 0.029
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0005 0.0007
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0031 0.0159
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Plasmodium falciparum serine repeat antigen 3 0.0209 0.0415 0.2168
Loa Loa (eye worm) thioredoxin reductase 0.0162 0.0314 0.0836
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.055 0.1136 0.1696
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0005 0.0005
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0027 0.0031 0.0071
Plasmodium falciparum serine repeat antigen 1 0.0209 0.0415 0.2168
Onchocerca volvulus 0.0015 0.0005 0.0023
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0027 0.0031 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0028 0.0032 0.0075
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.076 0.1581 0.4211
Echinococcus multilocularis serotonin receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus granulosus transcription factor eb 0.0065 0.0109 0.0163
Schistosoma mansoni carbon catabolite repressor protein 0.0027 0.0031 0.0046
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0005 0.0012
Plasmodium falciparum serine repeat antigen 2 0.0209 0.0415 0.2168
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0023 0.006
Echinococcus multilocularis traf and tnf receptor associated protein 0.0027 0.0031 0.003
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.006 0.01 0.0522
Echinococcus granulosus hypothetical protein 0.0015 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0136 0.0261 0.039
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0013 0.0001 0.0001
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0013 0.0001 0.0001
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0024 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Plasmodium vivax importin-beta 2, putative 0.0114 0.0214 0.1114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Echinococcus granulosus cathepsin L cysteine protease 0.0497 0.1024 0.1529
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0023 0.006
Echinococcus multilocularis neutral sphingomyelinase 0.0027 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0041 0.006 0.031
Echinococcus multilocularis glycine receptor subunit beta 0.0013 0.0001 0.0001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0136 0.026 0.069
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0005 0.0005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0136 0.0261 0.0261
Entamoeba histolytica cysteine proteinase, putative 0.0497 0.1024 0.5334
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0038 0.0196
Loa Loa (eye worm) hypothetical protein 0.0287 0.0581 0.1545
Toxoplasma gondii exonuclease III APE 0.0136 0.026 0.1355
Schistosoma mansoni lamin 0.0061 0.0103 0.0153
Schistosoma mansoni phosphoglucomutase 0.0044 0.0067 0.0099
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0025 0.0026 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0086
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0048 0.0074 0.0367
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0056 0.0091 0.0475
Loa Loa (eye worm) Smad1 0.0052 0.0082 0.0217
Leishmania major aldehyde dehydrogenase, putative 0.0041 0.006 0.029
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.008 0.0119
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0015 0.0004 0.0027
Schistosoma mansoni glutamate synthase 0.0015 0.0004 0.0006
Entamoeba histolytica cysteine protease, putative 0.0209 0.0415 0.2152
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0015 0.0005 0.0023
Brugia malayi GH02984p 0.072 0.1495 0.398
Brugia malayi Cathepsin L-like precursor 0.0918 0.1915 0.51
Brugia malayi Latrophilin receptor protein 2 0.0136 0.0261 0.0693
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Echinococcus granulosus cathepsin L 0.0209 0.0415 0.062
Brugia malayi Pax transcription factor protein 2 0.0169 0.033 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.0415 0.2152
Chlamydia trachomatis pyruvate kinase 0.0025 0.0026 0.2756
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.0056 0.0148
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0041 0.006 0.0089
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0017 0.0008 0.0053
Plasmodium falciparum glutathione reductase 0.0162 0.0314 0.1641
Echinococcus granulosus neuropeptide s receptor 0.1424 0.2985 0.446
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0745 0.1549 1
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0024 0.0023 0.0058
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0026 0.0133
Echinococcus granulosus expressed protein 0.0024 0.0023 0.0034
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0024 0.0023 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.008 0.0211
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0015 0.0004 0.0004
Echinococcus multilocularis importin subunit beta 1 0.0114 0.0214 0.0213
Onchocerca volvulus 0.0051 0.008 0.0414
Schistosoma mansoni hypothetical protein 0.3177 0.6693 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0076 0.0133 0.0345
Echinococcus granulosus g protein coupled receptor 0.0015 0.0005 0.0007
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0013 0.0001 0.0001
Echinococcus granulosus intermediate filament protein 0.0061 0.0103 0.0153
Loa Loa (eye worm) hypothetical protein 0.0412 0.0844 0.2247
Brugia malayi exodeoxyribonuclease III family protein 0.0136 0.026 0.069
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.041 0.0839 1
Giardia lamblia Cysteine protease 0.0209 0.0415 0.2868
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0021 0.009
Echinococcus multilocularis cathepsin L 0.0497 0.1024 0.1023
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0024 0.0023 0.0097
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0041 0.006 0.0376
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0455
Schistosoma mansoni opsin-like receptor 0.0015 0.0005 0.0007
Schistosoma mansoni biogenic amine receptor 0.0015 0.0005 0.0007
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0017 0.0008 0.0083
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0015 0.0004 0.0019
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0024 0.0023 0.0034
Onchocerca volvulus 0.0209 0.0415 0.2166
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Toxoplasma gondii cathepsin B 0.0697 0.1448 0.7561
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.055 0.1136 0.1696
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0052 0.0082 0.0217
Brugia malayi MAP kinase sur-1 0.0076 0.0133 0.0353
Schistosoma mansoni hypothetical protein 0.003 0.0036 0.0054
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0026 0.0068
Loa Loa (eye worm) RNA binding protein 0.0345 0.0703 0.187
Schistosoma mansoni inositol transporter 0.0079 0.0141 0.021
Schistosoma mansoni cathepsin S (C01 family) 0.0209 0.0415 0.062
Schistosoma mansoni cathepsin F (C01 family) 0.0918 0.1915 0.2861
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0024 0.0023 0.0034
Onchocerca volvulus Ribonuclease H1 homolog 0.0044 0.0067 0.0344
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0015 0.0004 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0209 0.0415 0.2152
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0005 0.0007
Giardia lamblia hypothetical protein 0.0027 0.0031 0.0211
Echinococcus granulosus glycine receptor subunit beta 0.0013 0.0001 0.0001
Leishmania major ribonuclease H1, putative 0.0044 0.0067 0.0326
Trypanosoma cruzi pyruvate kinase 2, putative 0.0025 0.0026 0.0059
Leishmania major hypothetical protein, conserved 0.0027 0.0031 0.0139
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0232
Brugia malayi hypothetical protein 0.0043 0.0064 0.0168
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0022 0.0018 0.0074
Echinococcus multilocularis sodium and chloride dependent glycine 0.0037 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0005 0.0007
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.008 0.008
Toxoplasma gondii cathepsin CPC1 0.0209 0.0415 0.2168
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Entamoeba histolytica cysteine protease, putative 0.0209 0.0415 0.2152
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0005 0.0023
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0013 0.0001 0.0001
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0079 0.0141 0.014
Schistosoma mansoni sodium/chloride dependent transporter 0.0037 0.0051 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0345 0.0703 0.1049
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Schistosoma mansoni glutamate synthase 0.0015 0.0004 0.0006
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0027 0.0031 0.0046
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0018 0.001 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0028
Trichomonas vaginalis maltase-glucoamylase, putative 0.0057 0.0094 0.0469
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0209 0.0415 0.2168
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0029 0.0044
Trypanosoma brucei hypothetical protein, conserved 0.0032 0.004 0.0186
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0023 0.0118
Mycobacterium ulcerans lipase LipD 0.0032 0.004 0.0249
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0027 0.0031 0.0139
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.008 0.0119
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0027 0.0031 0.008
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0455
Mycobacterium ulcerans glutamate synthase subunit beta 0.0015 0.0004 0.0019
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0013 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0136 0.026 0.0682
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0017 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus granulosus fmrfamide receptor 0.0015 0.0005 0.0007
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0139
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0136 0.0261 0.039
Echinococcus multilocularis nAChR subunit 0.0013 0.0001 0.0001
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0041 0.006 0.0148
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0007
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0041 0.006 0.0376
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0144 0.0278 0.0278
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0139
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0026 0.0133
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0005 0.0007
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0023 0.0023
Schistosoma mansoni alpha-glucosidase 0.0222 0.0442 0.066
Trichomonas vaginalis pyruvate kinase, putative 0.0025 0.0026 0.0115
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0041 0.006 0.0384
Giardia lamblia Thioredoxin reductase 0.0015 0.0004 0.0027
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0004 0.0019
Loa Loa (eye worm) PHD-finger family protein 0.0046 0.0071 0.0187
Echinococcus granulosus importin subunit beta 1 0.0114 0.0214 0.0319
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0004 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0697 0.1448 0.7556
Giardia lamblia Hypothetical protein 0.0209 0.0415 0.2868
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0015 0.0004 0.0027
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.041 0.0839 0.5416
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0497 0.1024 0.2718
Onchocerca volvulus 0.0024 0.0023 0.0118
Schistosoma mansoni biogenic amine receptor 0.0015 0.0005 0.0007
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0209 0.0415 0.2168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0057 0.0094 0.0248
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0004 0.0006
Trichomonas vaginalis helicase, putative 0.0023 0.0021 0.009
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0005 0.0005
Giardia lamblia Alcohol dehydrogenase 0.0041 0.006 0.041
Trypanosoma cruzi mitochondrial protein 99, putative 0.0027 0.0031 0.0071
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0041 0.006 0.0376
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0013 0.0001 0.0001
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0005 0.0007
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0013 0.0001 0.0001
Trypanosoma cruzi cruzipain precursor, putative 0.0287 0.0581 0.1538
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0032 0.004 0.0257
Giardia lamblia Encystation-specific protease 0.0209 0.0415 0.2868
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0005 0.0012
Echinococcus granulosus neuropeptide receptor A26 0.1424 0.2985 0.446
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0184 0.0363 0.1877
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0005 0.0012
Mycobacterium tuberculosis Probable esterase LipL 0.0032 0.004 0.0257
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0056 0.0092 0.0137
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0023 0.006
Brugia malayi SET domain containing protein 0.0017 0.0008 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0345 0.0703 0.1049
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1216 0.2544 0.6775
Toxoplasma gondii cathepsin CPC2 0.0209 0.0415 0.2168
Brugia malayi Papain family cysteine protease containing protein 0.0209 0.0415 0.1105
Brugia malayi Papain family cysteine protease containing protein 0.0918 0.1915 0.51
Brugia malayi follicle stimulating hormone receptor 0.0015 0.0005 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0209 0.0415 0.062
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.008 0.0414
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0024 0.0023 0.0034
Echinococcus multilocularis mothers against decapentaplegic 5 0.0052 0.0082 0.0082
Schistosoma mansoni bromodomain containing protein 0.0152 0.0295 0.0441
Echinococcus multilocularis cathepsin b 0.1788 0.3754 0.3754
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0024 0.0023 0.0022
Brugia malayi nuclear receptor RXR 0.0027 0.0029 0.0076
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0056 0.0091 0.0589
Giardia lamblia Glutamate synthase 0.0015 0.0004 0.0027
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0005 0.0012
Trypanosoma cruzi pyruvate kinase 2, putative 0.0025 0.0026 0.0059
Brugia malayi hypothetical protein 0.0027 0.0029 0.0076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0028
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0032 0.004 0.0249
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Brugia malayi G-protein coupled receptor 0.0015 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Toxoplasma gondii ribonuclease HI protein 0.0044 0.0067 0.0346
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0017 0.0009 0.0044
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0004 0.0021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0369 0.0752 0.4855
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.008 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0918 0.1915 1
Toxoplasma gondii pyruvate kinase PyK1 0.0025 0.0026 0.0136
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0094 0.0469
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0005 0.0007
Schistosoma mansoni cathepsin s 0.0287 0.0581 0.0867
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0001 0.0001
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0041 0.006 0.0157
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0013 0.0001 0.0001
Echinococcus granulosus glycine receptor subunit beta 0.0013 0.0001 0.0001
Mycobacterium leprae conserved hypothetical protein 0.0032 0.004 0.0459
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0431 0.0883 0.2352
Loa Loa (eye worm) hypothetical protein 0.0037 0.0051 0.0134
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Mycobacterium leprae Polyketide synthase Pks13 0.0025 0.0026 0.0291
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0042 0.0111
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0022 0.002 0.0082
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0027 0.0031 0.0139
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0104
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.041 0.0839 0.5416
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0041 0.006 0.0376
Loa Loa (eye worm) hypothetical protein 0.0209 0.0415 0.1105
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0005
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0027 0.0031 0.0139
Echinococcus granulosus beta LACTamase domain containing family member 0.0032 0.004 0.0059
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0209 0.0415 0.2168
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0081 0.0143 0.0143
Brugia malayi G-protein alpha subunit 0.0024 0.0023 0.0058
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0041 0.006 0.0148
Entamoeba histolytica cysteine proteinase, putative 0.0497 0.1024 0.5334
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0004 0.0035
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0139
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0005 0.0005
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0041 0.006 0.0376
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0076
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0032 0.004 0.0257
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0017 0.0009 0.0056
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0058
Brugia malayi nuclear receptor NHR-88 0.0051 0.008 0.0211
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0005 0.0005
Echinococcus granulosus lysosomal alpha glucosidase 0.0258 0.0518 0.0774
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Trichomonas vaginalis pyruvate kinase, putative 0.0025 0.0026 0.0115
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0024 0.0023 0.0034
Schistosoma mansoni coup transcription factor 0.0051 0.008 0.0119
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0027 0.0031 0.0139
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0136 0.026 0.0682
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0041 0.006 0.0376
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.008
Echinococcus granulosus GTP binding nuclear protein Ran 0.0084 0.015 0.0224
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.008
Giardia lamblia Cathepsin L-like protease 0.0209 0.0415 0.2868
Echinococcus granulosus ribonuclease H1 0.0044 0.0067 0.0099
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0005 0.0005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0136 0.026 0.1337
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.008 0.008
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0209 0.0415 0.2152
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0011 0.0028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0021 0.0018 0.0071
Schistosoma mansoni sodium/solute symporter 0.0079 0.0141 0.021
Toxoplasma gondii selenide, water dikinase 0.0015 0.0004 0.0021
Echinococcus granulosus serotonin receptor 0.0015 0.0005 0.0007
Brugia malayi conserved hypotetical protein 0.0024 0.0023 0.006
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0015 0.0004 0.0019
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0023 0.0035
Onchocerca volvulus 0.0079 0.0141 0.0731
Echinococcus multilocularis zinc finger protein 0.0054 0.0088 0.0087
Loa Loa (eye worm) nuclear factor I 0.0029 0.0033 0.0087
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0041 0.006 0.0384
Mycobacterium leprae conserved hypothetical protein 0.0017 0.0009 0.0089
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0017 0.0009 0.0177
Schistosoma mansoni mucolipin 0.004 0.0057 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Giardia lamblia Cathepsin B precursor 0.0209 0.0415 0.2868
Echinococcus multilocularis muscleblind protein 1 0.011 0.0205 0.0205
Trypanosoma brucei RNA editing exonuclease 2 0.0027 0.0031 0.0139
Schistosoma mansoni inositol transporter 0.0079 0.0141 0.021
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Giardia lamblia Cysteine protease 0.0209 0.0415 0.2868
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0157
Toxoplasma gondii histone lysine methyltransferase SET1 0.0207 0.041 0.2138
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.008 0.0211
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0065 0.0109 0.0289
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0209 0.0415 0.2168
Entamoeba histolytica cysteine protease, putative 0.0209 0.0415 0.2152
Plasmodium falciparum cysteine proteinase falcipain 3 0.0918 0.1915 1
Brugia malayi Muscleblind-like protein 0.011 0.0205 0.0544
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.008 0.0414
Plasmodium vivax ataxin-2 like protein, putative 0.0067 0.0114 0.0594
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0044 0.0067 0.244
Echinococcus multilocularis pyruvate kinase 0.002 0.0015 0.0015
Echinococcus multilocularis sodium and chloride dependent glycine 0.0037 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Trypanosoma cruzi cysteine proteinase, putative 0.0497 0.1024 0.2718
Schistosoma mansoni myosin xvIII 0.0015 0.0005 0.0007
Brugia malayi cathepsin L-like cysteine proteinase 0.0209 0.0415 0.1105
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0058
Schistosoma mansoni hypothetical protein 0.0084 0.0151 0.0225
Loa Loa (eye worm) hypothetical protein 0.0079 0.0141 0.0373
Treponema pallidum NADH oxidase 0.0056 0.0091 0.3403
Giardia lamblia Cysteine protease 0.0209 0.0415 0.2868
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0001 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0024 0.0023 0.0022
Trichomonas vaginalis bromodomain-containing protein, putative 0.006 0.01 0.0502
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Brugia malayi Serotonin receptor 0.0015 0.0005 0.0012
Echinococcus granulosus methyl CpG binding domain protein 2 0.0038 0.0054 0.008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0184 0.0363 0.0363
Brugia malayi nuclear receptor RXR 0.0024 0.0023 0.006
Echinococcus multilocularis expressed protein 0.0024 0.0023 0.0022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.008 0.0119
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0015 0.0004 0.0021
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0136 0.026 0.1337
Trypanosoma cruzi cysteine peptidase, putative 0.0497 0.1024 0.2718
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0109 0.0203 0.0537
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0136 0.026 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0232
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0041 0.006 0.0307
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0041 0.006 0.0384
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0745 0.1549 0.8086
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0013 0.0001 0.0001
Onchocerca volvulus Fatty acid synthase homolog 0.003 0.0037 0.0187
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0023 0.006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0032 0.004 0.0059
Plasmodium vivax vivapain-1 0.0497 0.1024 0.5343
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0005 0.0012
Leishmania major RNA-editing complex protein MP100, putative 0.0027 0.0031 0.0139
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0005 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0032 0.004 0.0186
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0005 0.0005
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0021 0.009
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0041 0.006 0.0157
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0287 0.0581 0.1545
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0027 0.0031 0.0139
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.008 0.0119
Brugia malayi hypothetical protein 0.0024 0.0023 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Echinococcus granulosus neuropeptide receptor 0.0015 0.0005 0.0007
Echinococcus granulosus geminin 0.3177 0.6693 1
Brugia malayi MH1 domain containing protein 0.0052 0.0082 0.0217
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0027 0.0031 0.0071
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0014 0.0002 0.0012
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0024 0.0023 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0209 0.0415 0.062
Schistosoma mansoni intermediate filament proteins 0.0061 0.0103 0.0153
Brugia malayi ecdysone receptor 0.0024 0.0023 0.006
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0056 0.0092 0.0092
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0027 0.0031 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Loa Loa (eye worm) aldehyde dehydrogenase 0.0041 0.006 0.0157
Schistosoma mansoni glutamate synthase 0.0015 0.0004 0.0006
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0024 0.0023 0.0034
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.006 0.0101 0.0266
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0011 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.0021 0.0018 0.0071
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0041 0.006 0.0148
Loa Loa (eye worm) hypothetical protein 0.0287 0.0581 0.1545
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0015 0.0004 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0911 0.19 0.19
Toxoplasma gondii HEAT repeat-containing protein 0.0114 0.0214 0.1114
Echinococcus multilocularis beta LACTamase domain containing family member 0.0032 0.004 0.004
Mycobacterium ulcerans polyketide synthase 0.0018 0.001 0.0059
Mycobacterium ulcerans thioesterase TesA 0.0014 0.0002 0.0007
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0005 0.0007
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0136 0.0261 0.039
Onchocerca volvulus 0.0912 0.1901 0.9927
Echinococcus granulosus cathepsin L 0.0497 0.1024 0.1529
Mycobacterium ulcerans dehydrogenase 0.0015 0.0004 0.0019
Giardia lamblia Cathepsin B precursor 0.0209 0.0415 0.2868
Plasmodium vivax unspecified product 0.0497 0.1024 0.5343
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0005 0.0005
Onchocerca volvulus Putative neutral sphingomyelinase 0.0027 0.0031 0.0156
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1788 0.3754 0.5609
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0209 0.0415 0.1105
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0038 0.009
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Mycobacterium leprae Probable lipase LipE 0.0032 0.004 0.0459
Echinococcus multilocularis neuropeptide s receptor 0.1424 0.2985 0.2985
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0029 0.0076
Schistosoma mansoni hypothetical protein 0.0166 0.0325 0.0484
Echinococcus granulosus glutamate synthase 0.0015 0.0004 0.0006
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0117 0.022 0.1147
Echinococcus multilocularis importin 5 0.0022 0.0018 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.004 0.0095
Brugia malayi Pre-SET motif family protein 0.0801 0.1668 0.4441
Brugia malayi G protein-coupled receptor 0.0015 0.0005 0.0012
Mycobacterium ulcerans ferredoxin reductase 0.0015 0.0004 0.0019
Plasmodium falciparum ferrodoxin reductase-like protein 0.0015 0.0004 0.0021
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0136 0.026 0.1355
Entamoeba histolytica hypothetical protein 0.0184 0.0363 0.1877
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0032 0.004 0.0104
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0027 0.0031 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni hypothetical protein 0.3177 0.6693 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.022 0.0438 0.0653
Echinococcus multilocularis ribonuclease H1 0.0044 0.0067 0.0066
Onchocerca volvulus 0.0015 0.0005 0.0023
Schistosoma mansoni smad1 5 8 and 0.0052 0.0082 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0018 0.0011 0.0028
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.006 0.0157
Plasmodium falciparum pyruvate kinase 0.0025 0.0026 0.0136
Brugia malayi Dopamine receptor 0.0015 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0076
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0027 0.0031 0.0139
Brugia malayi Calcitonin receptor-like protein seb-1 0.0431 0.0883 0.2352
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Brugia malayi tailless protein 0.0024 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0028
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.055 0.1136 0.1135
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0017 0.0008 0.0083
Schistosoma mansoni methyl-cpg binding protein mbd 0.0038 0.0054 0.008
Loa Loa (eye worm) glutathione reductase 0.0162 0.0314 0.0836
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.008 0.0211
Echinococcus granulosus cathepsin b 0.1788 0.3754 0.5609
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0184 0.0363 0.0542
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0048 0.0074 0.0187
Chlamydia trachomatis thioredoxin reductase 0.0015 0.0004 0.0295
Onchocerca volvulus Cathepsin F homolog 0.0918 0.1915 1
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.008 0.0211
Echinococcus granulosus thioredoxin glutathione reductase 0.0163 0.0317 0.0473
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Loa Loa (eye worm) DR-78 0.0024 0.0023 0.006
Mycobacterium leprae Probable polyketide synthase Pks1 0.0018 0.001 0.0109
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0032 0.004 0.0104
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0056 0.0091 0.0455
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0136 0.0261 0.0261
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0038 0.0176
Loa Loa (eye worm) hypothetical protein 0.0061 0.0103 0.0271
Plasmodium vivax SET domain protein, putative 0.0117 0.022 0.1147
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.008
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0056 0.0091 0.0581
Mycobacterium ulcerans thioesterase 0.0014 0.0002 0.0007
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0023 0.0097
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0024 0.0023 0.0058
Onchocerca volvulus 0.0061 0.0103 0.0532
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0091 0.0232
Entamoeba histolytica cysteine protease, putative 0.0209 0.0415 0.2152
Brugia malayi Smad1 0.0052 0.0082 0.0217
Onchocerca volvulus 0.0015 0.0005 0.0023
Schistosoma mansoni opsin-like receptor 0.0015 0.0005 0.0007
Brugia malayi nuclear hormone receptor 0.0051 0.008 0.0211
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0005 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Echinococcus granulosus pyruvate kinase 0.0025 0.0026 0.0039
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.008 0.0119
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0139
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0287 0.0581 0.1545
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0005 0.0012
Schistosoma mansoni hypothetical protein 0.0034 0.0045 0.0068
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0041 0.006 0.0376
Schistosoma mansoni hypothetical protein 0.0015 0.0005 0.0007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0136 0.026 0.1793
Trichomonas vaginalis ran, putative 0.0084 0.015 0.0763
Onchocerca volvulus 0.0015 0.0005 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Schistosoma mansoni adenoreceptor 0.0015 0.0005 0.0007
Brugia malayi cathepsin F-like cysteine proteinase 0.0209 0.0415 0.1105
Loa Loa (eye worm) latrophilin receptor protein 2 0.0136 0.0261 0.0693
Trypanosoma brucei trypanothione reductase 0.0162 0.0314 0.1624
Mycobacterium ulcerans hypothetical protein 0.0015 0.0004 0.0019
Leishmania major hypothetical protein, conserved 0.0027 0.0031 0.0139
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0084 0.015 0.0782
Mycobacterium ulcerans glutaminase 0.024 0.048 0.309
Trichomonas vaginalis ap endonuclease, putative 0.0136 0.026 0.1337
Entamoeba histolytica hypothetical protein 0.0017 0.0009 0.0024
Trichomonas vaginalis penicillin-binding protein, putative 0.0032 0.004 0.0186
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Brugia malayi acetyltransferase, GNAT family protein 0.0192 0.0379 0.1008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.008 0.0211
Echinococcus multilocularis glutamate synthase 0.0015 0.0004 0.0004
Toxoplasma gondii preprocathepsin c precursor, putative 0.0209 0.0415 0.2168
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0017 0.0009 0.0044
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.006 0.0089
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0004 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0497 0.1024 0.5334
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0041 0.006 0.0376
Trypanosoma cruzi ribonuclease H1, putative 0.0044 0.0067 0.0166
Trichomonas vaginalis alpha-glucosidase, putative 0.0057 0.0094 0.0469
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0017 0.0009 0.0048
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0048 0.0074 0.0196
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Brugia malayi Glycosyl hydrolases family 31 protein 0.0258 0.0518 0.1378
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0056 0.0091 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0011 0.0037
Trichomonas vaginalis ap endonuclease, putative 0.0136 0.026 0.1337
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0041 0.006 0.0376
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0071
Echinococcus multilocularis musashi 0.0061 0.0103 0.0102
Trichomonas vaginalis alpha-glucosidase, putative 0.0021 0.0018 0.0071
Trypanosoma brucei importin beta-1 subunit, putative 0.0114 0.0214 0.1096
Echinococcus granulosus L aminoadipate semialdehyde 0.006 0.0101 0.015
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0071
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0027 0.0031 0.0139
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Leishmania major endonuclease/exonuclease protein-like protein 0.0027 0.0031 0.0139
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0041 0.006 0.0089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0038 0.0038
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.004 0.0095
Echinococcus multilocularis GPCR, family 2 0.0136 0.0261 0.0261
Trichomonas vaginalis Phospholipase C precursor, putative 0.0027 0.0031 0.0139
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.008 0.0211
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0005 0.0007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.008 0.0119
Schistosoma mansoni survival motor neuron protein 0.0084 0.0151 0.0225
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Entamoeba histolytica Ran family GTPase 0.0084 0.015 0.0763
Entamoeba histolytica hypothetical protein 0.0016 0.0007 0.0016
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0005 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0004 0.0009
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.011 0.0206 0.0308
Giardia lamblia Histone acetyltransferase GCN5 0.005 0.0079 0.0546
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0041 0.006 0.0148
Entamoeba histolytica hypothetical protein 0.0092 0.0168 0.0858
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0021 0.0018 0.0089
Loa Loa (eye worm) cathepsin B 0.0697 0.1448 0.3856
Plasmodium vivax glutathione reductase, putative 0.0162 0.0314 0.1641
Mycobacterium ulcerans monoxygenase 0.0015 0.0004 0.0019
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0005 0.0007
Schistosoma mansoni GTP-binding protein alpha subunit 0.0024 0.0023 0.0034
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0076
Echinococcus granulosus high affinity choline transporter 1 0.072 0.1495 0.2233
Echinococcus granulosus synaptojanin 1 0.0027 0.0031 0.0046
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0023 0.0035
Echinococcus multilocularis high affinity choline transporter 1 0.072 0.1495 0.1495
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0015 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0011 0.012
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0136 0.026 0.167
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0038 0.0176
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0056 0.0091 0.0455
Schistosoma mansoni myst-related protein 0.0016 0.0007 0.001
Leishmania major trypanothione reductase 0.0162 0.0314 0.1624
Echinococcus granulosus dnaJ subfamily B 0.0911 0.19 0.2839
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0024 0.0023 0.0022
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0005 0.0007
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0057 0.0094 0.0469
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0005 0.0007
Brugia malayi MH2 domain containing protein 0.076 0.1581 0.4211
Leishmania major pyruvate kinase 0.0025 0.0026 0.0115
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0021 0.009
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0091 0.3403
Brugia malayi Thioredoxin reductase 0.0162 0.0314 0.0836
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0041 0.006 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0192 0.0379 0.0566
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0005 0.0007
Treponema pallidum ribonuclease H (rnhA) 0.0044 0.0067 0.244
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0918 0.1915 0.51
Treponema pallidum gamma-glutamyl phosphate reductase 0.0041 0.006 0.2165
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0016 0.0007 0.0046
Loa Loa (eye worm) programmed cell death 8 0.0015 0.0004 0.0009
Echinococcus granulosus cathepsin l cysteine peptidase 0.0918 0.1915 0.2861
Toxoplasma gondii NADPH-glutathione reductase 0.0056 0.0091 0.0475
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0017 0.0111
Giardia lamblia Ribonuclease H 0.0044 0.0067 0.0458
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Echinococcus granulosus transportin 1 0.0022 0.0018 0.0027
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0005 0.0005
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0017 0.0008 0.0045
Schistosoma mansoni zinc finger protein 0.0024 0.0023 0.0035
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0041 0.006 0.0148
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0022 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.055 0.1136 0.1696
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0015 0.0004 0.0035
Onchocerca volvulus 0.0018 0.0011 0.0055
Schistosoma mansoni neuropeptide receptor 0.0015 0.0005 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0041 0.006 0.0148
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0103 0.0271
Plasmodium vivax unspecified product 0.0287 0.0581 0.3032
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0018 0.0011 0.0065
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0015 0.0004 0.0006
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0209 0.0415 0.062
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0027 0.0031 0.0071
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Onchocerca volvulus 0.0169 0.033 0.172
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Echinococcus granulosus translational activator gcn1 0.0022 0.0018 0.0027
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0209 0.0415 0.2168
Onchocerca volvulus 0.0102 0.0188 0.0976
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0005 0.0007
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0041 0.006 0.0148
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0041 0.006 0.0384
Schistosoma mansoni smad 0.0023 0.0022 0.0032
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0084 0.015 0.0763
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1788 0.3754 0.5609
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0021 0.0018 0.0036
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0004 0.0021
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0209 0.0415 0.2168
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0018 0.0011 0.0073
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0038
Schistosoma mansoni importin-beta 2 0.0022 0.0018 0.0027
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0016 0.0007 0.0046
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0918 0.1915 0.51
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Loa Loa (eye worm) pax transcription factor protein 2 0.0169 0.033 0.0877
Brugia malayi Papain family cysteine protease containing protein 0.0209 0.0415 0.1105
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0024 0.0023 0.0022
Loa Loa (eye worm) hypothetical protein 0.0209 0.0415 0.1105
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0058
Plasmodium falciparum thioredoxin reductase 0.0056 0.0091 0.0475
Schistosoma mansoni cathepsin C 0.0209 0.0415 0.062
Toxoplasma gondii ABC1 family protein 0.0032 0.004 0.0206
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0104
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0023 0.0023
Schistosoma mansoni thyroid hormone receptor 0.0143 0.0275 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0209 0.0415 0.2152
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0023 0.0118
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0017 0.0009 0.0177
Echinococcus multilocularis lamin 0.0061 0.0103 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0209 0.0415 0.2152
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0022 0.0032
Schistosoma mansoni phosphoglucomutase 0.0044 0.0067 0.0099
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0162 0.0314 0.203
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.008 0.0119
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0209 0.0415 0.2168
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0038 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0018 0.0011 0.0065
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0745 0.1549 0.1549
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0497 0.1024 0.5334
Brugia malayi larval opioid receptor 0.0015 0.0005 0.0012
Mycobacterium ulcerans esterase/lipase LipP 0.0032 0.004 0.0249
Echinococcus multilocularis geminin 0.3177 0.6693 0.6693
Schistosoma mansoni methyl-cpg binding protein mbd 0.0038 0.0054 0.008
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0027 0.0031 0.0139
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0041 0.006 0.0148
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0918 0.1915 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0005 0.0007
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0041 0.006 0.0059
Echinococcus multilocularis transcription factor Dp 1 0.0028 0.0032 0.0031
Loa Loa (eye worm) kap beta 3 protein 0.0022 0.0018 0.0047
Schistosoma mansoni amine GPCR 0.0015 0.0005 0.0007
Mycobacterium tuberculosis Conserved protein 0.0032 0.004 0.0257
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1788 0.3754 0.5609
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0209 0.0415 0.2168
Brugia malayi Pyruvate kinase, M2 isozyme 0.0025 0.0026 0.0068
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0079 0.0141 0.0733
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0027 0.0031 0.0139
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0015 0.0004 0.0035
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.008 0.0211
Leishmania major phosphopantetheinyl transferase-like protein 0.0017 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0058
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.003 0.0036 0.0054
Onchocerca volvulus 0.0015 0.0005 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0031 0.0071
Brugia malayi hypothetical protein 0.0109 0.0203 0.0537
Schistosoma mansoni cpg binding protein 0.0102 0.0188 0.028
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.008 0.008
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0027 0.0031 0.003
Trypanosoma brucei glycosyl hydrolase-like protein 0.0021 0.0018 0.0071
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Schistosoma mansoni phosphoglucomutase 0.0044 0.0067 0.0099
Mycobacterium ulcerans Type I modular polyketide synthase 0.0017 0.0008 0.0045
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0041 0.006 0.029
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Plasmodium falciparum serine repeat antigen 6 0.0209 0.0415 0.2168
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0209 0.0415 0.2152
Echinococcus granulosus lamin dm0 0.0061 0.0103 0.0153
Schistosoma mansoni cathepsin B (C01 family) 0.0209 0.0415 0.062
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0004 0.0009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0091 0.0455
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0697 0.1448 0.7556
Onchocerca volvulus 0.0015 0.0005 0.0023
Entamoeba histolytica cysteine protease, putative 0.0209 0.0415 0.2152
Loa Loa (eye worm) hypothetical protein 0.0067 0.0114 0.0302
Onchocerca volvulus Pyruvate kinase homolog 0.0025 0.0026 0.0133
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0087
Plasmodium vivax vivapain-2 0.0918 0.1915 1
Schistosoma mansoni synaptojanin 0.0027 0.0031 0.0046
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0209 0.0415 0.062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Brugia malayi intermediate filament protein 0.0061 0.0103 0.0271
Mycobacterium leprae Probable pyruvate kinase PykA 0.0025 0.0026 0.0298
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0041 0.006 0.029
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0027 0.0031 0.0159
Echinococcus granulosus allatostatin A receptor 0.0015 0.0005 0.0007
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0024 0.0023 0.0034
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0918 0.1915 1
Onchocerca volvulus 0.0015 0.0005 0.0023
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0038 0.0196
Loa Loa (eye worm) bromodomain containing protein 0.0044 0.0066 0.0175
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0015 0.0004 0.0004
Mycobacterium tuberculosis Probable hydrolase 0.0032 0.004 0.0257
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.008 0.0119
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Schistosoma mansoni cathepsin F (C01 family) 0.0631 0.1307 0.1953
Echinococcus multilocularis transcription factor eb 0.0065 0.0109 0.0109
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0022 0.0022
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0014 0.0002 0.0011
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0005 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0018 0.0011 0.0037
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0497 0.1024 0.1529
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0021 0.009
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0027 0.0031 0.0046
Mycobacterium tuberculosis Probable lipase LipD 0.0032 0.004 0.0257
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0209 0.0415 0.1105
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0084 0.015 0.015
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0024 0.0023 0.0058
Echinococcus multilocularis sex peptide receptor 0.0015 0.0005 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0041 0.006 0.0384
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0024 0.0023 0.0058
Loa Loa (eye worm) hypothetical protein 0.0064 0.0109 0.0287
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0037 0.0051 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0068
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0209 0.0415 0.2868
Brugia malayi cathepsin Z-like cysteine proteinase 0.0209 0.0415 0.1105
Schistosoma mansoni GTP-binding protein alpha subunit 0.0024 0.0023 0.0034
Loa Loa (eye worm) hypothetical protein 0.0041 0.006 0.0157
Mycobacterium ulcerans beta-lactamase 0.0032 0.004 0.0249
Echinococcus multilocularis solute carrier family 5 0.0079 0.0141 0.014
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0048 0.0074 0.0074
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0035 0.0052
Brugia malayi aldehyde dehydrogenase 0.0041 0.006 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0209 0.0415 0.2152
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0345 0.0703 0.187
Loa Loa (eye worm) hypothetical protein 0.0136 0.0261 0.0693
Brugia malayi Bromodomain containing protein 0.0091 0.0164 0.0436
Giardia lamblia Cathepsin L precursor 0.0209 0.0415 0.2868
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.008 0.0119
Brugia malayi hypothetical protein 0.0184 0.0363 0.0965
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0918 0.1915 0.2861
Schistosoma mansoni aldehyde dehydrogenase 0.0745 0.1549 0.2315
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0497 0.1024 0.1529
Onchocerca volvulus 0.0918 0.1915 1
Schistosoma mansoni microtubule-associated protein tau 0.1007 0.2103 0.3141
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0005 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.1788 0.3754 1
Loa Loa (eye worm) fatty acid synthase 0.0017 0.0008 0.0018
Loa Loa (eye worm) pyruvate kinase 0.0025 0.0026 0.0068
Brugia malayi putative neuropeptide receptor 0.0015 0.0005 0.0012
Loa Loa (eye worm) cysteine protease 0.0918 0.1915 0.51
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0018 0.001 0.0059
Brugia malayi beta-lactamase 0.0032 0.004 0.0104
Schistosoma mansoni hypothetical protein 0.1216 0.2544 0.3801
Echinococcus granulosus histone lysine methyltransferase setb 0.0155 0.0301 0.0449
Plasmodium falciparum histone acetyltransferase GCN5 0.005 0.0079 0.0413
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0027 0.0031 0.0139
Giardia lamblia Pyruvate kinase 0.0025 0.0026 0.018
Brugia malayi AKH receptor 0.0015 0.0005 0.0012
Trypanosoma brucei glucosidase, putative 0.0057 0.0094 0.0469
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Echinococcus granulosus pyruvate kinase 0.0025 0.0026 0.0039
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0081 0.0143 0.0214
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.022 0.0328
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0631 0.1307 0.3475
Brugia malayi cathepsin F-like cysteine proteinase 0.0287 0.0581 0.1545
Plasmodium falciparum serine repeat antigen 8 0.0209 0.0415 0.2168
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0004 0.0027
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.0005 0.0012
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0103 0.0271
Plasmodium vivax serine-repeat antigen (SERA) 0.0209 0.0415 0.2168
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0018 0.0011 0.0065
Onchocerca volvulus 0.0918 0.1915 1
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0041 0.006 0.029
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0209 0.0415 0.2868
Echinococcus granulosus g protein coupled receptor 0.0015 0.0005 0.0007
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0024 0.0023 0.0034
Onchocerca volvulus 0.0109 0.0203 0.1054
Leishmania major aldehyde dehydrogenase, putative 0.0041 0.006 0.029
Onchocerca volvulus 0.0024 0.0023 0.0115
Schistosoma mansoni hypothetical protein 0.0027 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0918 0.1915 1
Giardia lamblia Cathepsin B precursor 0.0697 0.1448 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0163 0.0317 0.0316
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0056 0.0091 0.0091
Trypanosoma brucei PAB1-binding protein , putative 0.0067 0.0114 0.0575
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0027 0.0031 0.0139
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0023 0.0035
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.008 0.0119
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0015 0.0004 0.0027
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.006 0.0089
Loa Loa (eye worm) hypothetical protein 0.0051 0.008 0.0211
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0024 0.0023 0.0034
Echinococcus granulosus survival motor neuron protein 1 0.0412 0.0844 0.1261
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0192 0.0379 0.0379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0005 0.0005
Entamoeba histolytica cysteine proteinase 2 0.0497 0.1024 0.5334
Loa Loa (eye worm) ctsf protein 0.0918 0.1915 0.51
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0018 0.001 0.0059
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0104
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Onchocerca volvulus 0.0015 0.0005 0.0023
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0024 0.0023 0.0058
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0015 0.0004 0.0019
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0023 0.006
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0038 0.0038
Plasmodium falciparum acyl-CoA synthetase 0.0014 0.0002 0.0007
Onchocerca volvulus 0.0017 0.0008 0.0036
Entamoeba histolytica pyruvate kinase, putative 0.0018 0.001 0.0031
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0056 0.0091 0.0241
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.006 0.0157
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Entamoeba histolytica cysteine protease, putative 0.0209 0.0415 0.2152
Treponema pallidum hypothetical protein 0.0027 0.0031 0.1037
Loa Loa (eye worm) hypothetical protein 0.011 0.0205 0.0544
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0024 0.0023 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0027 0.0031 0.0159
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.008 0.0211
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0041 0.006 0.0059
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0041 0.006 0.029
Leishmania major cathepsin L-like protease 0.0918 0.1915 1
Brugia malayi Importin beta-1 subunit 0.0114 0.0214 0.0567
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0024 0.0023 0.0058
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0038 0.0176
Echinococcus granulosus sodium and chloride dependent glycine 0.0037 0.0051 0.0076
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0048 0.0074 0.0111
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0018 0.001 0.0067
Echinococcus granulosus sodium:glucose cotransporter 2 0.0079 0.0141 0.021
Echinococcus multilocularis glycine receptor subunit beta 0.0013 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.055 0.1136 0.1135
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0631 0.1307 0.3481
Echinococcus granulosus fetal alzheimer antigen falz 0.0056 0.0092 0.0137
Brugia malayi Cathepsin L-like cysteine proteinase 0.0631 0.1307 0.3481
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.008
Brugia malayi Cathepsin L-like precursor 0.0918 0.1915 0.51
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0023 0.0023
Brugia malayi cathepsin L-like precursor 0.0631 0.1307 0.3481
Brugia malayi hypothetical protein 0.0024 0.0023 0.006
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0036 0.0048 0.0072
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0024 0.0023 0.0034
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0027 0.0031 0.003
Toxoplasma gondii aldehyde dehydrogenase 0.0745 0.1549 0.809
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0745 0.1549 0.2315
Brugia malayi glutamate synthase 0.0015 0.0004 0.0009
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0029 0.0076
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.006 0.0376
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0025 0.0026 0.017
Echinococcus granulosus GPCR family 2 0.0136 0.0261 0.039
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0017 0.0044
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0013 0.0001 0.0001
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0029 0.0044
Echinococcus granulosus muscleblind protein 0.011 0.0205 0.0306
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0064 0.0109 0.0287
Trypanosoma brucei protein kinase, putative 0.0076 0.0133 0.0676
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0104
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0005 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.008 0.0211
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0015 0.0004 0.0021
Trypanosoma cruzi ribonuclease H1, putative 0.0044 0.0067 0.0166
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0369 0.0752 0.4855
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0041 0.006 0.0376
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0023 0.006
Echinococcus granulosus orexin receptor type 2 0.0015 0.0005 0.0007
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0209 0.0415 0.2152
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0052 0.0082 0.0082
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0038 0.0099
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0015 0.0004 0.0006
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0018 0.0095
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0021 0.009
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0024 0.0023 0.0058
Onchocerca volvulus 0.0024 0.0023 0.0115
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0076 0.0133 0.0676
Entamoeba histolytica hypothetical protein 0.0184 0.0363 0.1877
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0369 0.0752 0.4855
Schistosoma mansoni nuclear hormone receptor 0.0051 0.008 0.0119
Onchocerca volvulus 0.0117 0.022 0.1145
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0027 0.0031 0.008
Echinococcus multilocularis snurportin 1 0.1216 0.2544 0.2544
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0023 0.0035
Onchocerca volvulus 0.0015 0.0005 0.0023
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0209 0.0415 0.2168
Brugia malayi steroid hormone receptor 0.0051 0.008 0.0211
Loa Loa (eye worm) hypothetical protein 0.0029 0.0034 0.0088
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0094 0.0239
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0009
Giardia lamblia Cathepsin L precursor 0.0209 0.0415 0.2868
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.008 0.0211
Trichomonas vaginalis importin beta-1, putative 0.0092 0.0168 0.0858
Schistosoma mansoni cript-related 0.0027 0.0031 0.0046
Trichomonas vaginalis glutathione reductase, putative 0.0056 0.0091 0.0455
Entamoeba histolytica cysteine protease, putative 0.0497 0.1024 0.5334
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0048 0.0074 0.0367
Plasmodium falciparum DNase I-like protein, putative 0.0027 0.0031 0.0159
Loa Loa (eye worm) hypothetical protein 0.0018 0.001 0.0025
Giardia lamblia Cathepsin L precursor 0.0209 0.0415 0.2868
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0041 0.006 0.0157
Brugia malayi Papain family cysteine protease containing protein 0.0497 0.1024 0.2725
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0155 0.0301 0.0449
Loa Loa (eye worm) hypothetical protein 0.0631 0.1307 0.3481
Onchocerca volvulus 0.0024 0.0023 0.0115
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0005 0.0007
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0041 0.006 0.0089
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0091 0.0232
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0005 0.0007
Echinococcus granulosus TGF beta signal transducer SmadC 0.0052 0.0082 0.0123
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0038 0.0099
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0027 0.0031 0.0159
Schistosoma mansoni nAChR subunit 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0005 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.008 0.0211
Brugia malayi nuclear hormone receptor 0.0024 0.0023 0.006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0745 0.1549 1
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0024 0.0023 0.0034
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0015 0.0004 0.0021
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.003 0.0036 0.0036
Leishmania major 4-coumarate:coa ligase-like protein 0.0018 0.0011 0.0037
Brugia malayi hypothetical protein 0.0027 0.0029 0.0076
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0024 0.0023 0.0034
Brugia malayi hypothetical protein 0.0412 0.0844 0.2247
Echinococcus granulosus histone acetyltransferase KAT2B 0.006 0.01 0.0149
Brugia malayi hypothetical protein 0.0015 0.0005 0.0012
Brugia malayi Cathepsin L-like precursor 0.0918 0.1915 0.51
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0209 0.0415 0.2152

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 1 ug ml-1 Minimum inhibitory concentration against Mycobacterium tuberculosis H37Rv ATCC 27294 ChEMBL. 15780635
MIC (functional) = 1 ug ml-1 Minimum inhibitory concentration against Mycobacterium tuberculosis H37Rv ATCC 27294 ChEMBL. 15780635
MIC (functional) = 4 ug ml-1 Minimum inhibitory concentration against Mycobacterium tuberculosis sensitive clinical isolates; Range: 1-4 ug/ml ChEMBL. 15780635
MIC (functional) = 4 ug ml-1 Minimum inhibitory concentration against Mycobacterium tuberculosis resistant clinical isolates; Range: 1-4 ug/ml ChEMBL. 15780635
MIC (functional) = 4 ug ml-1 Minimum inhibitory concentration against Mycobacterium intracellulare ATCC 13950 ChEMBL. 15780635
MIC (functional) = 4 ug ml-1 Minimum inhibitory concentration against Mycobacterium tuberculosis sensitive clinical isolates; Range: 1-4 ug/ml ChEMBL. 15780635
MIC (functional) = 4 ug ml-1 Minimum inhibitory concentration against Mycobacterium tuberculosis resistant clinical isolates; Range: 1-4 ug/ml ChEMBL. 15780635
MIC (functional) = 8 ug ml-1 Minimum inhibitory concentration against Mycobacterium avium ATCC 49601 ChEMBL. 15780635

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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