Detailed information for compound 317768

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 575.599 | Formula: C28H28F3N3O5S
  • H donors: 3 H acceptors: 4 LogP: 4.18 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C([C@H]1CCC[C@@H]1C(=O)NCc1ccc(cc1)OC(F)(F)F)NCc1ccc(cc1)c1ccccc1S(=O)(=O)N
  • InChi: 1S/C28H28F3N3O5S/c29-28(30,31)39-21-14-10-19(11-15-21)17-34-27(36)24-6-3-5-23(24)26(35)33-16-18-8-12-20(13-9-18)22-4-1-2-7-25(22)40(32,37)38/h1-2,4,7-15,23-24H,3,5-6,16-17H2,(H,33,35)(H,34,36)(H2,32,37,38)/t23-,24-/m0/s1
  • InChiKey: ZRVISOBUJANNIH-ZEQRLZLVSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens sodium channel, voltage-gated, type IX, alpha subunit Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Echinococcus granulosus sodium channel protein Get druggable targets OG5_126819 All targets in OG5_126819
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania donovani calcium channel protein, putative Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania infantum calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania mexicana calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Leishmania major calcium channel protein, putative,ion transporter, putative Get druggable targets OG5_126819 All targets in OG5_126819
Echinococcus multilocularis sodium channel protein Get druggable targets OG5_126819 All targets in OG5_126819

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni gliotactin 0.0069 0.0281 0.0435
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0408
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0515 0.132
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0288 0.0738
Schistosoma mansoni histone deacetylase hda2 0.0331 0.1496 0.2321
Loa Loa (eye worm) hypothetical protein 0.0083 0.0349 0.0751
Loa Loa (eye worm) histone deacetylase 1 0.0277 0.1245 0.2698
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0118 0.0507 0.1095
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0178 0.0789 0.1707
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0362 0.0694
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Brugia malayi Pre-SET motif family protein 0.021 0.0937 0.2028
Echinococcus multilocularis microtubule associated protein 2 0.1399 0.6444 0.8503
Giardia lamblia DINP protein human, muc B family 0.0099 0.0421 0.2312
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0109 0.017
Schistosoma mansoni dishevelled 0.0009 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Echinococcus granulosus cpg binding protein 0.0031 0.0105 0.0163
Leishmania major DNA polymerase eta, putative 0.0118 0.0509 0.1307
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.014 0.0216
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0122 0.0592
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0109 0.0231
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0109 0.0144
Brugia malayi follicle stimulating hormone receptor 0.0032 0.0109 0.0231
Echinococcus granulosus orexin receptor type 2 0.0032 0.0109 0.017
Leishmania major importin beta-1 subunit, putative 0.0024 0.0072 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0012 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0507 0.0486
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0191 0.0942
Loa Loa (eye worm) hypothetical protein 0.0038 0.0136 0.029
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.005 0.0044
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0029 0.0098 0.0206
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0003 0.0005
Brugia malayi Importin beta-1 subunit 0.0029 0.0098 0.0206
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0007 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0009 0.0012
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0106 0.0452 0.1159
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0011 0.0026
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.01 0.0155
Schistosoma mansoni amine GPCR 0.0032 0.0109 0.0169
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0054 0.0053
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0023 0.0096
Schistosoma mansoni tyrosine kinase 0.0532 0.2428 0.3767
Brugia malayi jmjC domain containing protein 0.0016 0.0035 0.007
Toxoplasma gondii ck2 beta subunit 0.0037 0.0133 0.0132
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0118 0.0507 0.0486
Entamoeba histolytica hypothetical protein 0.0043 0.0162 0.1288
Trichomonas vaginalis spcc417.12 protein, putative 0.0069 0.0281 0.1398
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0486
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Brugia malayi Dopamine receptor protein 1 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.0515 0.0493
Mycobacterium ulcerans carboxylesterase, LipT 0.0069 0.0281 0.0259
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0122 0.0258
Echinococcus multilocularis expressed conserved protein 0.0187 0.0831 0.1096
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0092 0.039 0.0605
Schistosoma mansoni neuropeptide receptor 0.0032 0.0109 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.005 0.0125
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0027 0.0035
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0054 0.0137
Plasmodium vivax histone deacetylase 1, putative 0.0277 0.1245 0.1241
Schistosoma mansoni BC026374 protein (S09 family) 0.0069 0.0281 0.0435
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0109 0.017
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0035 0.0122 0.0203
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0023 0.0021
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.047 0.1013
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0108 0.0276
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0133 0.1216
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0408
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0035 0.0046
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0109 0.0169
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0122 0.0203
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0023 0.0067 0.014
Schistosoma mansoni glutaminase 0.0276 0.1239 0.1922
Schistosoma mansoni patched 1 0.0434 0.1976 0.3065
Echinococcus multilocularis replication factor c subunit 1 0.0049 0.0191 0.0252
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0092 0.039 0.0606
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0035 0.0122 0.01
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0023 0.0017
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0045 0.0171 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0136 0.0666
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0012 0.0017
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0109 0.017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0005 0.0005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0109 0.0995
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0171 0.0438
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1644 0.7579 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0126 0.0124
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0012 0.0017
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0015 0.002
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.1362 0.35
Loa Loa (eye worm) casein kinase II 0.0011 0.0012 0.0019
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.047 0.2356
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0011 0.001
Echinococcus multilocularis Immunoglobulin 0.0016 0.0035 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.01 0.0154
Echinococcus multilocularis para nitrobenzyl esterase 0.0069 0.0281 0.037
Mycobacterium ulcerans acetyl-CoA synthetase 0.0035 0.0122 0.01
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.01 0.0154
Schistosoma mansoni rotamase 0.0032 0.0112 0.0173
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0321 0.1451 0.1914
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0335 0.0721
Echinococcus multilocularis histone deacetylase 8 0.0137 0.0596 0.0786
Entamoeba histolytica phosphofructokinase, putative 0.011 0.047 0.3765
Brugia malayi Carboxylesterase family protein 0.0069 0.0281 0.0603
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0109 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0288 0.0738
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0406 0.0594
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0027 0.0052
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0018 0.0017
Echinococcus granulosus neuroglian 0.0016 0.0035 0.0054
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0184 0.0813 1
Echinococcus multilocularis snurportin 1 0.0314 0.1415 0.1868
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0452 0.2058 0.4462
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0096 0.0149
Trypanosoma cruzi histone deacetylase 1, putative 0.0277 0.1245 0.32
Toxoplasma gondii propionate-CoA ligase 0.0035 0.0122 0.0121
Echinococcus multilocularis Niemann Pick C1 protein 0.02 0.0887 0.117
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0106 0.0452 0.0701
Trichomonas vaginalis glutaminase, putative 0.0276 0.1239 0.6261
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0013
Entamoeba histolytica hypothetical protein 0.0043 0.0162 0.1288
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0035 0.0034
Onchocerca volvulus 0.0069 0.0281 0.26
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi hypothetical protein 0.0016 0.0035 0.0069
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0117 0.0504 0.0985
Mycobacterium ulcerans hypothetical protein 0.0118 0.0507 0.0486
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0133 0.0132
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0181 0.0802 0.206
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0053 0.0205 0.0525
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0054 0.0112
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0009 0.0001 0.0002
Mycobacterium ulcerans chorismate synthase 0.2166 1 1
Brugia malayi putative neuropeptide receptor 0.0032 0.0109 0.0231
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0109 0.0231
Giardia lamblia Flap structure-specific endonuclease 0.0053 0.0205 0.1113
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0009 0.0013
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0035 0.0122 0.0203
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Schistosoma mansoni amine GPCR 0.0032 0.0109 0.0169
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0054 0.0112
Onchocerca volvulus 0.0014 0.0027 0.0223
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.01 0.021
Onchocerca volvulus 0.0069 0.0281 0.26
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0281 0.0435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.01 0.021
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0263 0.118 0.183
Echinococcus multilocularis histone deacetylase 6 0.0325 0.1467 0.1936
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0012 0.0019
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0069 0.0281 0.0528
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0181 0.0802 0.206
Brugia malayi Serotonin receptor 0.0032 0.0109 0.0231
Schistosoma mansoni hypothetical protein 0.0032 0.0109 0.0169
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0003 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.01 0.021
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.0789 0.1041
Onchocerca volvulus 0.0032 0.0109 0.0995
Brugia malayi larval opioid receptor 0.0032 0.0109 0.0231
Echinococcus multilocularis BC026374 protein (S09 family) 0.0069 0.0281 0.037
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0171 0.0226
Onchocerca volvulus 0.0035 0.0122 0.1113
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0109 0.0144
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0109 0.0231
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0119 0.0515 0.2585
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0258
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0011 0.001
Leishmania major trypanothione reductase 0.0038 0.0137 0.035
Mycobacterium ulcerans hypothetical protein 0.0159 0.0699 0.0678
Schistosoma mansoni hypothetical protein 0.0043 0.0162 0.025
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0016 0.0035 0.0054
Entamoeba histolytica acyl-coA synthetase, putative 0.0118 0.0507 0.4067
Loa Loa (eye worm) carboxylesterase 0.0069 0.0281 0.0603
Echinococcus granulosus alkaline phosphatase 0.0164 0.0721 0.112
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0515 0.132
Schistosoma mansoni ran 0.0022 0.0062 0.0095
Leishmania major hypothetical protein, conserved 0.0016 0.0035 0.0087
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0011 0.0012 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0109 0.0144
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0109 0.0169
Brugia malayi steroid hormone receptor 0.003 0.01 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0081 0.0205
Plasmodium vivax chorismate synthase 0.2166 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0109 0.0144
Schistosoma mansoni thyroid hormone receptor 0.003 0.01 0.0154
Brugia malayi ecdysteroid receptor 0.003 0.01 0.021
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0122 0.0592
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0109 0.0144
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0012 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Echinococcus multilocularis somatostatin receptor 0.0032 0.0109 0.0144
Toxoplasma gondii patched family protein 0.0012 0.0018 0.0017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0005 0.0005
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0003 0.0004
Schistosoma mansoni terminal deoxycytidyl transferase 0.0092 0.039 0.0605
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0099 0.0786
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0019
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0112 0.0237
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.005 0.0225
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.047 0.0448
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0171 0.1368
Onchocerca volvulus 0.0069 0.0281 0.26
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0109 0.0144
Trypanosoma brucei cdc2-related kinase 1 0.0045 0.0171 0.0438
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0112 0.0237
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0486
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0003 0.0005
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0007 0.001
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0171 0.0438
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0136 0.018
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0109 0.0169
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0027 0.0052
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0847 0.3889 1
Schistosoma mansoni hypothetical protein 0.0083 0.0344 0.0533
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Echinococcus granulosus g protein coupled receptor 0.0032 0.0109 0.017
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0109 0.017
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Onchocerca volvulus 0.0032 0.0109 0.0995
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0016 0.0035 0.0053
Schistosoma mansoni acetylcholinesterase 0.0069 0.0281 0.0435
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0181 0.0802 0.206
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0133 0.0282
Brugia malayi G-protein coupled receptor 0.0032 0.0109 0.0231
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0277 0.1245 0.6294
Schistosoma mansoni DNA helicase recq5 0.002 0.0054 0.0083
Schistosoma mansoni exonuclease 0.0011 0.0011 0.0017
Schistosoma mansoni flap endonuclease-1 0.0048 0.0182 0.0282
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0214 0.0547
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) hypothetical protein 0.0134 0.0581 0.1255
Brugia malayi neuropeptide F receptor 0.0032 0.0109 0.0231
Echinococcus granulosus dna polymerase kappa 0.0119 0.0515 0.0798
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0054 0.0137
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.005 0.0065
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0362 0.0694
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0258
Loa Loa (eye worm) hypothetical protein 0.02 0.0887 0.1919
Brugia malayi Carboxylesterase family protein 0.0407 0.185 0.401
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0035 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0191 0.0942
Trichomonas vaginalis histone deacetylase, putative 0.0277 0.1245 0.6294
Schistosoma mansoni 6-phosphofructokinase 0.011 0.047 0.0728
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0133 0.0132
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0018
Plasmodium falciparum replication factor C subunit 1, putative 0.0049 0.0191 0.019
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0109 0.0144
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Schistosoma mansoni microtubule-associated protein tau 0.1399 0.6444 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0054 0.0072
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.0789 0.1041
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.0769 0.1662
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0035 0.0122 0.097
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0005 0.0007
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0012 0.0018
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0362 0.0501
Leishmania major 4-coumarate:coa ligase-like protein 0.0118 0.0507 0.1301
Schistosoma mansoni ap endonuclease 0.0019 0.005 0.0076
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trypanosoma brucei histone deacetylase 4 0.0325 0.1467 0.377
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0244 0.0379
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0005 0.0005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.005 0.0247
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0035 0.007
Leishmania major DNA polymerase eta, putative 0.0054 0.0214 0.0547
Echinococcus multilocularis epidermal growth factor receptor 0.1002 0.4608 0.608
Echinococcus multilocularis sodium channel protein 0.0106 0.0452 0.0596
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.01 0.021
Echinococcus multilocularis roundabout 2 0.0016 0.0035 0.0046
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0012 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0258
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0035 0.0122 0.01
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0007 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0081 0.008
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.01 0.021
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0335 0.0442
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0099 0.0476
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Toxoplasma gondii histone deacetylase HDAC5 0.0137 0.0596 0.0594
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.005 0.0101
Schistosoma mansoni hypothetical protein 0.0083 0.0344 0.0533
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0027 0.0035
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0011 0.0012 0.0033
Schistosoma mansoni 6-phosphofructokinase 0.011 0.047 0.0728
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0009 0.0005 0.0004
Trypanosoma cruzi histone deacetylase, putative 0.0137 0.0596 0.1529
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0062 0.0082
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0408
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0398 0.1804 0.9131
Onchocerca volvulus 0.0032 0.0109 0.0995
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0035 0.0122 0.0203
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0104 0.0103
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0171 0.0844
Echinococcus granulosus histone deacetylase 6 0.0325 0.1467 0.2276
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0012 0.0017
Leishmania major DNA polymerase kappa, putative 0.0099 0.0421 0.108
Schistosoma mansoni DNA ligase IV 0.0049 0.0191 0.0295
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0159 0.0405
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0027 0.0041
Echinococcus multilocularis protein dispatched 1 0.0447 0.2032 0.2681
Brugia malayi hypothetical protein 0.0014 0.0027 0.0052
Trypanosoma brucei unspecified product 0.0113 0.0484 0.1241
Loa Loa (eye worm) histone methyltransferase 0.001 0.0009 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0847 0.3889 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0109 0.0231
Trypanosoma brucei DNA polymerase IV, putative 0.0113 0.0484 0.1241
Brugia malayi XPG I-region family protein 0.0011 0.0011 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.01 0.021
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0027 0.0035
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0035 0.0122 0.0189
Entamoeba histolytica hypothetical protein 0.0043 0.0162 0.1288
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0799 0.7449
Trichomonas vaginalis rotamase, putative 0.0032 0.0108 0.0523
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.007
Schistosoma mansoni topbp1 0.0049 0.0191 0.0295
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0027 0.0042
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0007 0.0016
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0109 0.017
Schistosoma mansoni histone deacetylase 1 2 3 0.0137 0.0596 0.0923
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0003 0.0004
Trichomonas vaginalis histone deacetylase, putative 0.0277 0.1245 0.6294
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0117 0.0504 0.0483
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0104 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.01 0.0154
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0133 0.0206
Entamoeba histolytica Flap nuclease, putative 0.0053 0.0205 0.1642
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0174 0.0769 0.1192
Entamoeba histolytica DNA-repair protein, putative 0.0011 0.0011 0.0081
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0035 0.0087
Onchocerca volvulus 0.0035 0.0122 0.1113
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0099 0.0094
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0011 0.001
Echinococcus multilocularis histone deacetylase 1 0.0277 0.1245 0.1643
Schistosoma mansoni acetyl-CoA synthetase 0.0035 0.0122 0.0188
Echinococcus granulosus muscleblind protein 0.0452 0.2058 0.3193
Echinococcus multilocularis bloom syndrome protein 0.002 0.0054 0.0072
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0027 0.0052
Schistosoma mansoni dep domain containing protein 0.0009 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0137 0.0596 0.1287
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0011 0.0012 0.0018
Trypanosoma brucei DNA polymerase eta, putative 0.0118 0.0509 0.1307
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.01 0.0132
Trypanosoma cruzi histone deacetylase, putative 0.0137 0.0596 0.1529
Onchocerca volvulus 0.0152 0.0668 0.6222
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0277 0.1245 0.6294
Leishmania major histone deacetylase, putative 0.0325 0.1467 0.377
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0349 0.0751
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0847 0.3889 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0335 0.052
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0109 0.017
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0035 0.0046
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus granulosus geminin 0.0327 0.1479 0.2295
Trichomonas vaginalis conserved hypothetical protein 0.0434 0.1976 1
Treponema pallidum NADH oxidase 0.0013 0.0023 0.0169
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0023 0.0043
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0099 0.0098
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0171 0.0924
Onchocerca volvulus 0.0012 0.0018 0.0139
Echinococcus granulosus roundabout 2 0.0016 0.0035 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.01 0.021
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0237 0.0312
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Schistosoma mansoni hypothetical protein 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Brugia malayi Myosin head containing protein 0.0012 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.01 0.0155
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.01 0.0132
Brugia malayi DKFZp564C0469 protein 0.0049 0.0191 0.0408
Echinococcus multilocularis sex peptide receptor 0.0032 0.0109 0.0144
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0012 0.0017
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0095 0.0241
Brugia malayi CHE-14 protein 0.0434 0.1976 0.4284
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.1362 0.35
Plasmodium vivax DNA repair protein RAD2, putative 0.0011 0.0011 0.0006
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0035 0.0053
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0202 0.0516
Schistosoma mansoni biogenic amine receptor 0.0032 0.0109 0.0169
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Echinococcus granulosus expressed protein 0.0032 0.0112 0.0174
Schistosoma mansoni chromosome transmission fidelity factor 0.0049 0.0191 0.0295
Trypanosoma brucei unspecified product 0.0064 0.0257 0.0659
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.01 0.021
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.0398 0.1804 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0053 0.0205 0.0204
Loa Loa (eye worm) hypothetical protein 0.0263 0.118 0.2556
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0092 0.039 0.0841
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0109 0.0144
Echinococcus granulosus tumor protein p63 0.0672 0.3076 0.4774
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0109 0.017
Brugia malayi Pre-SET motif family protein 0.0031 0.0104 0.022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0699 0.1384
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0027 0.0042
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0072 0.034
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0507 0.0486
Echinococcus granulosus cyclin dependent kinase 0.0045 0.0171 0.0266
Entamoeba histolytica phosphofructokinase, putative 0.011 0.047 0.3765
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Entamoeba histolytica recQ family helicase, putative 0.002 0.0054 0.0427
Onchocerca volvulus 0.0012 0.0018 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Onchocerca volvulus 0.0032 0.0109 0.0995
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0023 0.0055
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0108 0.0276
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.01 0.0155
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0104 0.0137
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0095 0.0241
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0088 0.0369 0.0348
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.018 0.0796 0.1722
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0027 0.0041
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0109 0.017
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0005 0.0007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0335 0.0721
Brugia malayi Flap endonuclease-1 0.0053 0.0205 0.044
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0012 0.0085
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.047 0.0726
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0109 0.0144
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.01 0.0132
Brugia malayi Carboxylesterase family protein 0.0407 0.185 0.401
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0847 0.3889 0.844
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0005 0.0005
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0109 0.0144
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0406 0.0785
Entamoeba histolytica acyl-CoA synthetase, putative 0.0118 0.0507 0.4067
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0137 0.035
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0161 0.025
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0362 0.0694
Loa Loa (eye worm) acetyltransferase 0.0146 0.0639 0.1381
Brugia malayi jmjC domain containing protein 0.0016 0.0035 0.007
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Entamoeba histolytica phosphofructokinase, putative 0.011 0.047 0.3765
Plasmodium falciparum histone deacetylase 2 0.0325 0.1467 0.1466
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0639 0.0991
Leishmania major hypothetical protein, conserved 0.0026 0.0081 0.0205
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0321 0.1451 0.2251
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0133 0.1058
Brugia malayi jmjC domain containing protein 0.0016 0.0035 0.007
Trypanosoma cruzi DNA polymerase eta, putative 0.0118 0.0509 0.1307
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.01 0.0155
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0161 0.0156
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0003 0.0004
Toxoplasma gondii ATPase, AAA family protein 0.0049 0.0191 0.019
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0109 0.0144
Loa Loa (eye worm) hypothetical protein 0.0044 0.0165 0.0352
Schistosoma mansoni thyroid hormone receptor 0.003 0.01 0.0154
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0035 0.0046
Trypanosoma cruzi FHA domain containing protein, putative 0.0049 0.0191 0.0488
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0035 0.0053
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0136 0.0211
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0012 0.0015
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.062 0.0962
Brugia malayi Csnk2b protein 0.0037 0.0133 0.0282
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0072 0.034
Loa Loa (eye worm) hypothetical protein 0.0026 0.0081 0.0169
Brugia malayi hypothetical protein 0.0016 0.0035 0.0069
Echinococcus granulosus snurportin 1 0.0314 0.1415 0.2196
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.005 0.0524
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0539 0.2461 0.3819
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0011 0.0012 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0109 0.0169
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.01 0.0155
Echinococcus multilocularis flap endonuclease GEN 1 0.0011 0.0011 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0347 0.0664
Echinococcus multilocularis Niemann Pick C1 protein 0.0634 0.2901 0.3827
Echinococcus granulosus twitchin 0.0017 0.0041 0.0064
Brugia malayi Histone deacetylase family protein 0.0325 0.1467 0.3179
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0203
Entamoeba histolytica histone deacetylase, putative 0.0277 0.1245 1
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0109 0.0144
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0003 0.0004
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0349 0.046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Echinococcus granulosus cyclin dependent kinase 1 0.0045 0.0171 0.0266
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0012 0.0017
Echinococcus multilocularis 0.031 0.1398 0.1844
Echinococcus multilocularis carboxylesterase 5A 0.0407 0.185 0.244
Echinococcus granulosus cyclin dependent kinase 5 0.0045 0.0171 0.0266
Echinococcus granulosus exonuclease 1 0.0011 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0023 0.0021
Echinococcus multilocularis geminin 0.0327 0.1479 0.1952
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0005 0.0008
Loa Loa (eye worm) hypothetical protein 0.0118 0.0507 0.1095
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0136 0.0348
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0062 0.0315
Loa Loa (eye worm) hypothetical protein 0.0088 0.0369 0.0795
Echinococcus multilocularis protein patched 0.0434 0.1976 0.2607
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0027 0.0042
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0027 0.0041
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.01 0.0132
Echinococcus multilocularis muscleblind protein 0.0452 0.2058 0.2715
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0005 0.0007
Echinococcus granulosus sodium channel protein 0.0106 0.0452 0.0701
Echinococcus granulosus GPCR family 2 0.0081 0.0335 0.052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Echinococcus multilocularis Immunoglobulin 0.0016 0.0035 0.0046
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.01 0.021
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0184 0.0813 0.0792
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0109 0.0169
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.01 0.0905
Trichomonas vaginalis histone deacetylase, putative 0.0277 0.1245 0.6294
Schistosoma mansoni nephrin 0.0016 0.0035 0.0053
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0062 0.0128
Echinococcus granulosus sterol regulatory element binding protein 0.0434 0.1976 0.3066
Trypanosoma cruzi histone deacetylase 1, putative 0.0277 0.1245 0.32
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0035 0.0122 0.0258
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0162 0.025
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Echinococcus multilocularis cyclin dependent kinase 5 0.0045 0.0171 0.0226
Mycobacterium tuberculosis Probable reductase 0.0086 0.0362 0.0694
Brugia malayi ORL1-like opioid receptor 0.0032 0.0109 0.0231
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0108 0.0276
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0035 0.0122 0.0121
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0335 0.0442
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0847 0.3889 0.3876
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0054 0.0072
Brugia malayi hypothetical protein 0.0012 0.0018 0.0032
Leishmania major DNA damage repair protein, putative 0.0029 0.0095 0.0241
Echinococcus granulosus acetylcholinesterase 0.0407 0.185 0.287
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0486
Brugia malayi casein kinase II, putaitve 0.0011 0.0012 0.0019
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0069 0.0281 0.037
Echinococcus multilocularis cyclin dependent kinase 0.0045 0.0171 0.0226
Toxoplasma gondii patched family protein 0.0012 0.0018 0.0017
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0109 0.0231
Echinococcus granulosus somatostatin receptor 0.0032 0.0109 0.017
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0313 0.0414
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0023 0.0188
Giardia lamblia hypothetical protein 0.0011 0.0011 0.0034
Mycobacterium ulcerans hypothetical protein 0.0029 0.0095 0.0072
Trichomonas vaginalis DNA polymerase eta, putative 0.0119 0.0515 0.2585
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Schistosoma mansoni hypothetical protein 0.0085 0.0357 0.0552
Echinococcus granulosus histone deacetylase 3 0.0277 0.1245 0.1932
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0099 0.0077
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0122 0.0258
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus granulosus 6 phosphofructokinase 0.011 0.047 0.0729
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.005 0.0077
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0023 0.0055
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0171 0.0844
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0035 0.0054
Brugia malayi histone deacetylase 3 (HD3) 0.0277 0.1245 0.2698
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0133 0.0132
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0027 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0099 0.0476
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.047 0.5728
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0054 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0136 0.018
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0011 0.0011 0.0015
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0011 0.0012 0.0019
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0171 0.0366
Brugia malayi RNA binding protein 0.0076 0.0313 0.0674
Onchocerca volvulus 0.0118 0.0507 0.4719
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0109 0.0231
Schistosoma mansoni protein kinase 0.0009 0.0001 0.0001
Trypanosoma cruzi cdc2-related kinase 3 0.0045 0.0171 0.0438
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0117 0.0504 0.0985
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0043 0.0056
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0035 0.0122 0.0121
Entamoeba histolytica hypothetical protein 0.0181 0.0802 0.644
Onchocerca volvulus 0.0012 0.0018 0.0139
Brugia malayi hypothetical protein 0.0017 0.0039 0.0077
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0011 0.0012 0.0019
Brugia malayi 6-phosphofructokinase 0.011 0.047 0.1014
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0109 0.0231
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0137 0.0234
Loa Loa (eye worm) hypothetical protein 0.0181 0.0799 0.1728
Onchocerca volvulus 0.003 0.01 0.0905
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.01 0.0132
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0109 0.017
Brugia malayi phosphofructokinase 0.011 0.047 0.1013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Echinococcus granulosus neuropeptide receptor 0.0032 0.0109 0.017
Schistosoma mansoni histone deacetylase 4 5 0.0325 0.1467 0.2276
Trypanosoma brucei exonuclease, putative 0.0011 0.0011 0.0026
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0062 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0035 0.0122 0.01
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0109 0.0169
Brugia malayi Patched related family protein 10 0.0012 0.0018 0.0032
Trichomonas vaginalis exonuclease%2C+putative 0.0011 0.0011 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0191 0.0488
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0095 0.0241
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0035 0.0054
Brugia malayi jmjC domain containing protein 0.0059 0.0237 0.0507
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0027 0.0223
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0049 0.0191 0.0169
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0407 0.185 0.2869
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0027 0.0052
Brugia malayi AMP-binding enzyme family protein 0.0118 0.0507 0.1095
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Schistosoma mansoni DNA helicase recq1 0.002 0.0054 0.0083
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0301 0.1356 0.1336
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0035 0.0046
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0012 0.0018
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0104 0.0162
Schistosoma mansoni histone deacetylase 0.0277 0.1245 0.1932
Echinococcus granulosus epidermal growth factor receptor 0.1002 0.4608 0.715
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0099 0.0476
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0062 0.0057
Brugia malayi hypothetical protein 0.0152 0.0668 0.1443
Schistosoma mansoni hypothetical protein 0.0081 0.0335 0.0519
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.0515 0.0493
Onchocerca volvulus 0.0012 0.0018 0.0139
Brugia malayi protein C24B5.3 0.0012 0.0018 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.01 0.0132
Echinococcus multilocularis activin receptor type 0.0009 0.0001 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0515 0.132
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0053 0.0205 0.0525
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0003 0.0005
Brugia malayi MH2 domain containing protein 0.012 0.0519 0.1122
Schistosoma mansoni cpg binding protein 0.0029 0.0097 0.015
Loa Loa (eye worm) hypothetical protein 0.0188 0.0833 0.1803
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.0802 0.1244
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0092 0.039 0.0515
Leishmania major pantothenate kinase subunit, putative 0.0009 0.0002 0.0001
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0011 0.0011 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Leishmania major DNA polymerase kappa, putative 0.0029 0.0095 0.0241
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0072 0.034
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0054 0.0249
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0109 0.0169
Echinococcus multilocularis hyperpolarization activated cyclic 0.0011 0.0012 0.0015
Echinococcus granulosus sex peptide receptor 0.0032 0.0109 0.017
Brugia malayi histone deacetylase 11 0.0137 0.0596 0.1287
Brugia malayi Protein kinase domain containing protein 0.0045 0.0171 0.0366
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0118 0.0507 0.0486
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0335 0.052
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0937 0.2028
Plasmodium vivax DNA repair protein REV1, putative 0.0029 0.0095 0.009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Schistosoma mansoni hypothetical protein 0.0327 0.1479 0.2295
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0011 0.0012 0.0018
Brugia malayi G protein-coupled receptor 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0008 0.0012
Brugia malayi glutathione reductase 0.0038 0.0137 0.0291
Loa Loa (eye worm) hypothetical protein 0.0126 0.0545 0.1177
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0095 0.0241
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0452 0.2058 0.4462
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.003 0.01 0.0158
Schistosoma mansoni hypothetical protein 0.0083 0.0349 0.054
Schistosoma mansoni vesicular amine transporter 0.0023 0.0066 0.0102
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0109 0.0144
Brugia malayi Protein kinase domain containing protein 0.0321 0.1451 0.3144
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.01 0.021
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0418 0.0647
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0159 0.0405
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0043 0.0066
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Toxoplasma gondii hypothetical protein 0.0009 0.0003 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Brugia malayi Dopamine receptor 0.0032 0.0109 0.0231
Brugia malayi AMP-binding enzyme family protein 0.0118 0.0507 0.1095
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.01 0.0132
Echinococcus granulosus histone deacetylase 1 0.0277 0.1245 0.1932
Entamoeba histolytica acyl-CoA synthetase, putative 0.0118 0.0507 0.4067
Brugia malayi hypothetical protein 0.0016 0.0035 0.0069
Onchocerca volvulus 0.0098 0.0418 0.3882
Loa Loa (eye worm) flap endonuclease-1 0.0053 0.0205 0.044
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0109 0.0231
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0369 0.0795
Schistosoma mansoni histone deacetylase 0.0277 0.1245 0.1932
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.01 0.0154
Echinococcus multilocularis insulin receptor 0.0321 0.1451 0.1914
Brugia malayi AMP-binding enzyme family protein 0.0118 0.0507 0.1095
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) TK/EGFR protein kinase 0.1002 0.4608 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0515 0.132
Schistosoma mansoni biogenic amine receptor 0.0032 0.0109 0.0169
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.01 0.0155
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0191 0.0942
Plasmodium falciparum chorismate synthase 0.2166 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) steroid hormone receptor 0.003 0.01 0.021
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.1893 0.2498
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0191 0.0488
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0054 0.0053
Trypanosoma cruzi histone deacetylase, putative 0.0325 0.1467 0.377
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0035 0.0122 0.031
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Onchocerca volvulus 0.0032 0.0109 0.0995
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0301 0.1356 0.2576
Entamoeba histolytica exonuclease, putative 0.0011 0.0011 0.0081
Giardia lamblia Casein kinase II beta chain 0.0011 0.0012 0.0036
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0049 0.0191 0.2277
Schistosoma mansoni zinc finger protein 0.0014 0.0027 0.0041
Toxoplasma gondii thioredoxin reductase 0.0038 0.0137 0.0136
Schistosoma mansoni tyrosine kinase 0.0321 0.1451 0.2251
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0098 0.0249
Onchocerca volvulus 0.0032 0.0109 0.0995
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0011 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.01 0.021
Echinococcus granulosus replication factor c subunit 1 0.0049 0.0191 0.0296
Echinococcus granulosus para nitrobenzyl esterase 0.0069 0.0281 0.0436
Echinococcus multilocularis dna polymerase eta 0.0118 0.0509 0.0672
Schistosoma mansoni amine GPCR 0.0032 0.0109 0.0169
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0023 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0421 0.108
Plasmodium falciparum acyl-CoA synthetase 0.0088 0.0369 0.0368
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0191 0.0942
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0098 0.0249
Schistosoma mansoni neuropeptide receptor 0.0032 0.0109 0.0169
Onchocerca volvulus 0.0035 0.0122 0.1113
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0109 0.0144
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0122 0.031
Entamoeba histolytica recQ family DNA helicase 0.001 0.0009 0.0062
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0104 0.0161
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0159 0.0405
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0136 0.0348
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0009 0.002
Echinococcus granulosus serotonin receptor 0.0032 0.0109 0.017
Echinococcus granulosus histone deacetylase 7 0.0325 0.1467 0.2276
Brugia malayi nuclear receptor NHR-88 0.0014 0.0027 0.0052
Schistosoma mansoni hypothetical protein 0.0327 0.1479 0.2295
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0023 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0171 0.0265
Entamoeba histolytica protein kinase, putative 0.0181 0.0802 0.644
Plasmodium vivax acetyl-CoA synthetase, putative 0.0035 0.0122 0.0117
Onchocerca volvulus 0.0012 0.0018 0.0139
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0118 0.0507 0.0804
Brugia malayi Niemann-Pick C1 protein precursor 0.02 0.0887 0.1919
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0027 0.0052
Onchocerca volvulus 0.0049 0.0191 0.1759
Echinococcus granulosus dna polymerase eta 0.0118 0.0509 0.079
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0035 0.0122 0.01
Schistosoma mansoni cpg binding protein 0.0031 0.0105 0.0162
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0012 0.0032
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0062 0.0156
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0164 0.0721 0.0952
Leishmania major histone deacetylase, putative 0.0325 0.1467 0.377
Echinococcus granulosus tar DNA binding protein 0.0076 0.0313 0.0486
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0099 0.0094
Echinococcus multilocularis serotonin receptor 0.0032 0.0109 0.0144
Echinococcus multilocularis tumor protein p63 0.0672 0.3076 0.4059
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0109 0.017
Brugia malayi protein C24B5.3 0.0012 0.0018 0.0032
Echinococcus granulosus dnaJ subfamily B 0.0417 0.1893 0.2938
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0049 0.0191 0.019
Echinococcus multilocularis neuroligin 0.0069 0.0281 0.037
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0164 0.0721 0.0952
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0109 0.0144
Loa Loa (eye worm) patched family protein 0.0012 0.0018 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Loa Loa (eye worm) patched family protein 0.0012 0.0018 0.0032
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0203
Giardia lamblia Exonuclease 1 0.0011 0.0011 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0099 0.0476
Trypanosoma brucei cdc2-related kinase 3 0.0045 0.0171 0.0438
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.005 0.0125
Schistosoma mansoni alkaline phosphatase 0.0164 0.0721 0.1119
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0054 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0011 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0515 0.132
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0081 0.008
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0011 0.0012 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0314 0.1415 0.3067
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0069 0.0281 0.0528
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0109 0.0231
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.005 0.0048
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0335 0.0721
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0035 0.0122 0.0258
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0007 0.0016
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0159 0.0405
Echinococcus multilocularis histone deacetylase 7 0.0325 0.1467 0.1936
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0507 0.0486
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0099 0.1119
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0062 0.0096
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0095 0.0241
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0023 0.0021
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0109 0.0231
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0011 0.0011 0.0017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0109 0.0144
Brugia malayi Calcitonin receptor-like protein seb-1 0.0255 0.1142 0.2473
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0011 0.0031
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0203
Plasmodium vivax exonuclease I, putative 0.0011 0.0011 0.0006
Brugia malayi Thioredoxin reductase 0.0038 0.0137 0.0291
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0035 0.0122 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus granulosus microtubule associated protein 2 0.1399 0.6444 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus multilocularis histone deacetylase 3 0.0277 0.1245 0.1643
Schistosoma mansoni hypothetical protein 0.0314 0.1415 0.2196
Echinococcus multilocularis alkaline phosphatase 0.0164 0.0721 0.0952
Schistosoma mansoni protein kinase 0.0009 0.0001 0.0001
Echinococcus granulosus Immunoglobulin 0.0016 0.0035 0.0054
Brugia malayi Fibronectin type III domain containing protein 0.0016 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.007
Brugia malayi hypothetical protein 0.0043 0.0162 0.0344
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Onchocerca volvulus 0.0035 0.0122 0.1113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0054 0.0249
Brugia malayi RE15519p 0.0032 0.0109 0.0231
Echinococcus granulosus dual specificity 0.0181 0.0802 0.1245
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0109 0.0144
Onchocerca volvulus 0.0012 0.0018 0.0139
Brugia malayi Melatonin receptor type 1A 0.0032 0.0109 0.0231
Brugia malayi Carboxylesterase family protein 0.0069 0.0281 0.0603
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0133 0.1216
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0164 0.0721 0.112
Onchocerca volvulus 0.0031 0.0104 0.0947
Trypanosoma brucei histone deacetylase, putative 0.0325 0.1467 0.377
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0486
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0109 0.0169
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0027 0.0035
Echinococcus granulosus epidermal growth factor receptor 0.0539 0.2461 0.3819
Onchocerca volvulus 0.0032 0.0109 0.0995
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Schistosoma mansoni hypothetical protein 0.0012 0.0015 0.0023
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0006 0.0007
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Schistosoma mansoni hypothetical protein 0.0083 0.0349 0.054
Loa Loa (eye worm) glutaminase 0.0276 0.1239 0.2684
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0136 0.0348
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0847 0.3889 0.6035
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0023 0.0035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.01 0.021
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0639 0.0843
Plasmodium falciparum exonuclease I, putative 0.0011 0.0011 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0789 0.1224
Schistosoma mansoni tyrosine kinase 0.0539 0.2461 0.3819
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0109 0.0144
Entamoeba histolytica hypothetical protein 0.0049 0.0191 0.1524
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0005 0.001
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0062 0.0061
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0398 0.1804 0.9131
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0023 0.0055
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0244 0.0378
Trichomonas vaginalis histone deacetylase, putative 0.0277 0.1245 0.6294
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.005 0.0506
Brugia malayi nuclear receptor NHR-88 0.003 0.01 0.021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Brugia malayi nuclear receptor NHR-67 0.0014 0.0027 0.0052
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0181 0.0802 0.1736
Echinococcus multilocularis muscleblind protein 1 0.0452 0.2058 0.2715
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0118 0.0507 0.0991
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0088 0.0369 0.0709
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0109 0.0231
Loa Loa (eye worm) histone deacetylase 0.0325 0.1467 0.3179
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0237 0.0366
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Toxoplasma gondii histone deacetylase HDAC4 0.0137 0.0596 0.0594
Schistosoma mansoni protein kinase 0.0009 0.0001 0.0001
Entamoeba histolytica deoxycytidyl transferase, putative 0.0092 0.039 0.3128
Loa Loa (eye worm) hypothetical protein 0.0067 0.0271 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0191 0.0942
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0012 0.0015
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Toxoplasma gondii hypothetical protein 0.0012 0.0018 0.0017
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0009 0.0001 0.0002
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0049 0.0191 0.1524
Leishmania major histone deacetylase, putative 0.0277 0.1245 0.32
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0552 0.2518 0.3907
Schistosoma mansoni myosin xvIII 0.0032 0.0109 0.0169
Schistosoma mansoni neuropeptide receptor 0.0032 0.0109 0.0169
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0144 0.115
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Loa Loa (eye worm) hypothetical protein 0.0105 0.0448 0.0966
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0109 0.017
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0519 0.1122
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0136 0.029
Trypanosoma cruzi histone deacetylase, putative 0.0325 0.1467 0.377
Plasmodium vivax acyl-CoA synthetase, putative 0.0088 0.0369 0.0364
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0035 0.0087
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0069 0.0281 0.1398
Echinococcus granulosus Niemann Pick C1 protein 0.0634 0.2901 0.4501
Onchocerca volvulus Protein patched homolog 0.0012 0.0018 0.0139
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0109 0.0169
Schistosoma mansoni neuropeptide receptor 0.0032 0.0109 0.0169
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0099 0.0098
Brugia malayi jmjC domain containing protein 0.0061 0.0244 0.0524
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Plasmodium vivax JmjC domain containing protein 0.0016 0.0035 0.003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0109 0.017
Loa Loa (eye worm) glutaminase 2 0.0276 0.1239 0.2684
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0161 0.079
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0408
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0009 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0109 0.0169
Onchocerca volvulus Protein patched homolog 0.0012 0.0018 0.0139
Schistosoma mansoni neuroligin 3 (S09 family) 0.0069 0.0281 0.0435
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0349 0.054
Entamoeba histolytica protein kinase domain containing protein 0.0181 0.0802 0.644
Brugia malayi nuclear hormone receptor 0.0014 0.0027 0.0052
Brugia malayi Patched related family protein 4 0.0012 0.0018 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0288 0.0738
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus multilocularis dna polymerase kappa 0.0119 0.0515 0.0679
Giardia lamblia Histone deacetylase 0.0277 0.1245 0.6893
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0081 0.0076
Loa Loa (eye worm) hypothetical protein 0.0255 0.1142 0.2473
Echinococcus multilocularis serotonin receptor 0.0032 0.0109 0.0144
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0136 0.0212
Echinococcus granulosus carboxylesterase 5A 0.0407 0.185 0.287
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0035 0.0122 0.01
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.005 0.0125
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0109 0.0144
Trypanosoma cruzi histone deacetylase, putative 0.0325 0.1467 0.377
Loa Loa (eye worm) patched family protein 0.0012 0.0018 0.0032
Brugia malayi ImpB/MucB/SamB family protein 0.0118 0.0509 0.11
Brugia malayi glutaminase DH11.1 0.0276 0.1239 0.2684
Echinococcus multilocularis flap endonuclease 1 0.0053 0.0205 0.0271
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Brugia malayi Carboxylesterase family protein 0.0069 0.0281 0.0603
Onchocerca volvulus 0.0032 0.0109 0.0995
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.024 0.0239
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1068 0.4912 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0011 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0081 0.0205
Plasmodium vivax importin-beta 2, putative 0.0029 0.0098 0.0093
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0045 0.0171 0.017
Loa Loa (eye worm) hypothetical protein 0.0118 0.0509 0.11
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) histone deacetylase 3 0.0277 0.1245 0.2698
Schistosoma mansoni tyrosine kinase 0.0532 0.2428 0.3767
Echinococcus granulosus activin receptor type 0.0009 0.0001 0.0002
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0184 0.0813 1
Plasmodium falciparum histone deacetylase 1 0.0277 0.1245 0.1244
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0053 0.0205 0.0525
Brugia malayi Cyclic-nucleotide gated cation channel 0.0011 0.0012 0.0019
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.02 0.0887 0.7117
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0035 0.0053
Plasmodium vivax glutathione reductase, putative 0.0038 0.0137 0.0132
Echinococcus multilocularis epidermal growth factor receptor 0.0539 0.2461 0.3247
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0054 0.0112
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0136 0.0348
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0062 0.0156
Schistosoma mansoni tyrosine kinase 0.0321 0.1451 0.2251
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0109 0.017
Onchocerca volvulus Histone deacetylase 10 homolog 0.0137 0.0596 0.5547
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0109 0.0144
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.047 0.062
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0012 0.0018
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0181 0.0802 0.206
Schistosoma mansoni coup transcription factor 0.003 0.01 0.0154
Trichomonas vaginalis flap endonuclease-1, putative 0.0053 0.0205 0.1016
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0349 0.046
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0313 0.0674
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.01 0.0154
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0029 0.0095 0.0094
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0054 0.0053
Trypanosoma brucei histone deacetylase 3 0.0325 0.1467 0.377
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0109 0.017
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.1362 0.35
Schistosoma mansoni ran 0.0022 0.0062 0.0095
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0009 0.0005 0.0004
Plasmodium vivax flap endonuclease 1, putative 0.0053 0.0205 0.02
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0001 0.0001
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0108 0.0276
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0136 0.0729
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) acetylcholinesterase 1 0.0407 0.185 0.401
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0104 0.0137
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0005 0.0007
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0003 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Onchocerca volvulus 0.0029 0.0097 0.0884
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0362 0.0694
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0347 0.0664
Onchocerca volvulus 0.0032 0.0109 0.0995
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0035 0.0054
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0136 0.0212
Schistosoma mansoni tyrosine kinase 0.1002 0.4608 0.715
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0045 0.0171 0.0438
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0109 0.0144
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0012 0.0018
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0136 0.0212
Toxoplasma gondii hypothetical protein 0.0049 0.0188 0.0186
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0054 0.0273
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0035 0.0069
Brugia malayi nuclear receptor RXR 0.0014 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0081 0.0335 0.0721
Echinococcus granulosus hyperpolarization activated cyclic 0.0011 0.0012 0.0018
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0035 0.0122 0.0161
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0161 0.016
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0137 0.0132
Plasmodium vivax SET domain protein, putative 0.0031 0.0104 0.0099
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0122 0.031
Loa Loa (eye worm) patched family protein 0.0012 0.0018 0.0032
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0054 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.01 0.021
Brugia malayi Dopamine receptor protein 2 0.0032 0.0109 0.0231
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Schistosoma mansoni opsin-like receptor 0.0032 0.0109 0.0169
Schistosoma mansoni adenoreceptor 0.0032 0.0109 0.0169
Echinococcus granulosus phd:f box containing protein 0.0016 0.0035 0.0054
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0009 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0408
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus multilocularis histone deacetylase 0.0325 0.1467 0.1936
Brugia malayi tailless protein 0.0014 0.0027 0.0052
Trypanosoma cruzi cdc2-related kinase 1 0.0045 0.0171 0.0438
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0109 0.0169
Brugia malayi hypothetical protein 0.0012 0.0018 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Loa Loa (eye worm) hypothetical protein 0.0434 0.1976 0.4284
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0109 0.0169
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0035 0.0122 0.0121
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0171 0.0265
Brugia malayi hypothetical protein 0.0126 0.0545 0.1177
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0122 0.0258
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.01 0.0132
Echinococcus granulosus defective proboscis extension response 0.0016 0.0035 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0035 0.0069
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0045 0.0171 0.0266
Schistosoma mansoni hypothetical protein 0.0083 0.0344 0.0533
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0109 0.0169
Loa Loa (eye worm) histone deacetylase 7A 0.0325 0.1467 0.3179
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0109 0.0231
Schistosoma mansoni tyrosine kinase 0.0539 0.2461 0.3819
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Brugia malayi hypothetical protein 0.0049 0.0191 0.0408
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Schistosoma mansoni topbp1 0.0049 0.0191 0.0295
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.047 0.1205
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0023 0.0088
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Echinococcus granulosus FTZ F1 alpha 0.003 0.01 0.0155
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0098 0.0129
Schistosoma mansoni nuclear hormone receptor 0.003 0.01 0.0154
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0136 0.0666
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0012 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0347 0.0664
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.01 0.0905
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0035 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0035 0.0122 0.0203
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.031
Brugia malayi polk-prov protein 0.0055 0.0219 0.0469
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.039 0.0841
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Loa Loa (eye worm) hypothetical protein 0.0126 0.0545 0.1177
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0016 0.0035 0.0053
Plasmodium falciparum histone deacetylase, putative 0.0325 0.1467 0.1466
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.01 0.021
Plasmodium vivax histone deacetylase, putative 0.0325 0.1467 0.1463
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0099 0.0476
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Echinococcus granulosus g protein coupled receptor 0.0032 0.0109 0.017
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0109 0.017
Trypanosoma brucei chrX additional, unordered contigs 0.0029 0.0095 0.0241
Loa Loa (eye worm) carboxylesterase 0.0069 0.0281 0.0603
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0109 0.0169
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0109 0.0231
Leishmania major hypothetical protein, conserved 0.0011 0.0011 0.0026
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0109 0.0144
Trypanosoma brucei histone deacetylase 1 0.0277 0.1245 0.32
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0112
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0136 0.0211
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0099 0.0098
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0012 0.0017
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0178 0.0789 0.1707
Schistosoma mansoni importin beta-1 0.0029 0.0098 0.0151
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0847 0.3889 0.6035
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.01 0.0155
Plasmodium falciparum flap endonuclease 1 0.0053 0.0205 0.0204
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0237 0.0312
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0191 0.0942
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0005 0.0008
Onchocerca volvulus 0.0014 0.0027 0.0223
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0009 0.0002 0.0001
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0049 0.0191 0.0408
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0624 0.1603
Brugia malayi N-terminal motif family protein 0.0181 0.0799 0.1728
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0023 0.0021
Schistosoma mansoni alkaline phosphatase 0.0164 0.0721 0.1119
Trichomonas vaginalis histone deacetylase, putative 0.0277 0.1245 0.6294
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0099 0.0077
Trichomonas vaginalis replication factor C large subunit, putative 0.0049 0.0191 0.0942
Schistosoma mansoni opsin-like receptor 0.0032 0.0109 0.0169
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.047 0.0914
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0069 0.0281 0.0436
Loa Loa (eye worm) histone deacetylase 11 0.0137 0.0596 0.1287
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0067 0.014
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0847 0.3889 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0122 0.0258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0347 0.0664
Leishmania major GTP-binding protein, putative 0.0022 0.0062 0.0156
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0081 0.008
Onchocerca volvulus 0.0069 0.0281 0.26
Toxoplasma gondii histone deacetylase HDAC3 0.0277 0.1245 0.1244
Loa Loa (eye worm) hypothetical protein 0.0118 0.0507 0.1095
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0095 0.0241
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.005 0.0125
Brugia malayi hypothetical protein 0.0014 0.0027 0.0052
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0035 0.0034
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0005 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.01 0.0154
Schistosoma mansoni tyrosine kinase 0.0532 0.2428 0.3767
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.01 0.0154
Schistosoma mansoni hypothetical protein 0.0083 0.0344 0.0533
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0109 0.017
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0027 0.0223
Plasmodium falciparum DNA repair protein RAD2, putative 0.0011 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0012 0.0015
Echinococcus granulosus bloom syndrome protein 0.002 0.0054 0.0084
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0109 0.0144
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0109 0.0231
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi Pax transcription activation domain interacting protein 0.0049 0.0191 0.0408
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0005 0.0032
Echinococcus multilocularis nibrin 0.0049 0.0191 0.0252
Entamoeba histolytica exonuclease, putative 0.0011 0.0011 0.0081
Loa Loa (eye worm) hypothetical protein 0.0407 0.185 0.401
Entamoeba histolytica protein kinase, putative 0.0181 0.0802 0.644
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0023 0.0017
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0133 0.0339
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0624 0.1603
Schistosoma mansoni hypothetical protein 0.0081 0.0335 0.0519
Trypanosoma brucei histone deacetylase 2 0.0137 0.0596 0.1529
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0005 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0281 0.0435
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Brugia malayi Furin-like cysteine rich region family protein 0.1002 0.4608 1
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0133 0.0205
Brugia malayi hypothetical protein 0.0026 0.0081 0.0169
Schistosoma mansoni ap endonuclease 0.0019 0.005 0.0076
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0118 0.0507 0.0991
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.0398 0.1804 0.9131
Schistosoma mansoni hypothetical protein 0.0083 0.0349 0.054
Plasmodium falciparum importin beta, putative 0.0029 0.0098 0.0097
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0137 0.0291
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0023 0.0088
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0023 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0515 0.132
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Schistosoma mansoni opsin-like receptor 0.0032 0.0109 0.0169
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0099 0.0098
Toxoplasma gondii histone deacetylase HDAC2 0.0277 0.1245 0.1244
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0098 0.0097
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0315 0.1424 0.3085
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.01 0.021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0035 0.0069
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0406 0.0785
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0109 0.017
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0162 0.0251
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0012 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0109 0.0169
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0035 0.0053
Echinococcus granulosus allatostatin A receptor 0.0032 0.0109 0.017
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0045 0.0171 0.0438
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0566 0.2586 0.4013
Brugia malayi G-protein coupled receptor 0.0032 0.0109 0.0231
Schistosoma mansoni hypothetical protein 0.0032 0.0109 0.0169
Schistosoma mansoni DNA polymerase eta 0.0118 0.0509 0.0789
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0109 0.017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0789 0.1224
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0062 0.0128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0789 0.1224
Giardia lamblia Replication factor C, subunit 1 0.0049 0.0191 0.1032
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0136 0.018
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0313 0.0674
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0011 0.0031
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0005 0.001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.01 0.021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0005 0.001
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0003 0.0004
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1068 0.4912 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0194 0.0863 0.1867
Brugia malayi Patched protein homolog 1 0.0012 0.0018 0.0032
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0015 0.0024
Schistosoma mansoni amine GPCR 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.0055 0.0219 0.0469
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Loa Loa (eye worm) DR-78 0.0014 0.0027 0.0052
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0162 0.0213
Echinococcus multilocularis acetylcholinesterase 0.0407 0.185 0.244
Schistosoma mansoni nuclear receptor 0.0014 0.0027 0.0041
Treponema pallidum DNA ligase (lig) 0.0049 0.0191 0.2262
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0109 0.0144
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0349 0.0541
Echinococcus multilocularis histone deacetylase 6 0.0331 0.1496 0.1974
Loa Loa (eye worm) XPG I-region family protein 0.0011 0.0011 0.0018
Brugia malayi 6-phosphofructokinase 0.011 0.047 0.1013
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0112 0.0541
Loa Loa (eye worm) hypothetical protein 0.0847 0.3889 0.844
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0097 0.0205
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0049 0.0191 0.0408
Schistosoma mansoni 3-dehydroquinate synthase 0.0117 0.0504 0.0782
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0011 0.0012 0.0015
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0011 0.0011 0.0017
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0191 0.0942
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0301 0.1356 0.1355
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0035 0.0053
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0054 0.0214 0.0213
Mycobacterium tuberculosis Carboxylesterase LipT 0.0069 0.0281 0.0528
Entamoeba histolytica cell division protein kinase 2, putative 0.0045 0.0171 0.1368
Brugia malayi Histone deacetylase 1 0.0277 0.1245 0.2698
Echinococcus granulosus Protein patched homolog 1 0.0434 0.1976 0.3066
Brugia malayi Histone deacetylase family protein 0.0325 0.1467 0.3179
Entamoeba histolytica recQ family helicase, putative 0.001 0.0007 0.0048
Loa Loa (eye worm) hypothetical protein 0.0069 0.0281 0.0603
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.005 0.0225
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0007 0.0016
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0847 0.3889 0.5131
Brugia malayi GnHR receptor homolog 0.0032 0.0109 0.0231
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0027 0.0041
Echinococcus granulosus acetylcholinesterase 0.0407 0.185 0.287
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0109 0.017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Leishmania major histone deacetylase, putative 0.0277 0.1245 0.32
Schistosoma mansoni hypothetical protein 0.0417 0.1893 0.2937
Echinococcus granulosus neuropeptide receptor 0.0032 0.0109 0.017
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0136 0.0666
Echinococcus multilocularis histone deacetylase 6 0.0325 0.1467 0.1936
Brugia malayi nuclear receptor RXR 0.0016 0.0035 0.0069
Leishmania major ATP-dependent phosphofructokinase 0.011 0.047 0.1205
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0109 0.017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.047 0.2356
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0191 0.0942
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0133 0.0175
Toxoplasma gondii patched family protein 0.0012 0.0018 0.0017
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Echinococcus granulosus histone deacetylase 6 0.0331 0.1496 0.2322
Trichomonas vaginalis rotamase, putative 0.0032 0.0112 0.0541
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0013
Schistosoma mansoni amine GPCR 0.0032 0.0109 0.0169
Loa Loa (eye worm) carboxylesterase 0.0407 0.185 0.401
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0191 0.0942
Loa Loa (eye worm) hypothetical protein 0.018 0.0796 0.1722
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.01 0.021
Entamoeba histolytica hypothetical protein 0.0024 0.0072 0.0571
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0027 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0313 0.0486
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0016 0.0035 0.0046
Plasmodium falciparum DNA repair protein REV1, putative 0.0029 0.0095 0.0094
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0109 0.0144
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0023 0.0055
Chlamydia trachomatis dehyroquinate synthase 0.0117 0.0504 0.0483
Brugia malayi CXXC zinc finger family protein 0.0029 0.0097 0.0205
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0144 0.0773
Onchocerca volvulus 0.0032 0.0109 0.0995
Schistosoma mansoni histone deacetylase hda2 0.0137 0.0596 0.0923
Echinococcus granulosus neuroligin 0.0069 0.0281 0.0436
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.01 0.021
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0109 0.017
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0035 0.0122 0.0203
Echinococcus multilocularis dual specificity 0.0181 0.0802 0.1059
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0035 0.0034
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0035 0.007
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.01 0.0154
Loa Loa (eye worm) hypothetical protein 0.0174 0.0769 0.1662
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0118 0.0507 0.0486
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0164 0.0721 0.0952
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0109 0.0144
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0109 0.017
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0035 0.0054
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0237 0.0367
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.0789 0.1224
Onchocerca volvulus 0.0012 0.0018 0.0139
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0009 0.0004
Brugia malayi cell division control protein 2 homolog 0.0045 0.0171 0.0366
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0109 0.017
Brugia malayi hypothetical protein 0.0032 0.0109 0.0231
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0099 0.0521
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0133 0.0128
Plasmodium vivax patched family protein, putative 0.0012 0.0018 0.0013
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0109 0.0169
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0161 0.079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.01 0.021
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0255 0.1142 0.2473
Plasmodium vivax replication factor C subunit 1, putative 0.0049 0.0191 0.0186
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0088 0.0369 0.0348
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0012 0.0018
Echinococcus granulosus importin subunit beta 1 0.0029 0.0098 0.0152
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0054 0.0249
Echinococcus multilocularis neuroglian 0.0016 0.0035 0.0046
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0005 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0122 0.0203
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0109 0.017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0001 0.0001
Echinococcus multilocularis cpg binding protein 0.0031 0.0105 0.0139
Brugia malayi Patched related family protein 12 0.0012 0.0018 0.0032
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0515 0.132
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0133 0.1058
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0184 0.0813 0.0792
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0406 0.0785
Onchocerca volvulus 0.0032 0.0109 0.0995
Plasmodium falciparum thioredoxin reductase 0.0038 0.0137 0.0136
Onchocerca volvulus Bile acid receptor homolog 0.003 0.01 0.0905
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.0011 0.0031
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0027 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0092 0.039 0.0752
Brugia malayi TAR-binding protein 0.0076 0.0313 0.0674
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0027 0.0041
Brugia malayi AKH receptor 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0277 0.1245 0.2698
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.01 0.0155
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0081 0.0205
Loa Loa (eye worm) TK/INSR protein kinase 0.0321 0.1451 0.3144
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0005 0.0007
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0133 0.0339
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0108 0.0861
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0109 0.0144
Loa Loa (eye worm) phosphofructokinase 0.011 0.047 0.1013
Loa Loa (eye worm) hypothetical protein 0.0088 0.0369 0.0795
Brugia malayi Muscleblind-like protein 0.0452 0.2058 0.4462
Toxoplasma gondii chorismate synthase, putative 0.2166 1 1
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0115 0.0495 0.0767
Trichomonas vaginalis ran, putative 0.0022 0.0062 0.0288
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0277 0.1245 0.6294
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Echinococcus multilocularis GPCR, family 2 0.0081 0.0335 0.0442
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0095 0.0241
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0164 0.0721 0.112
Loa Loa (eye worm) hypothetical protein 0.0031 0.0104 0.022
Echinococcus granulosus histone deacetylase 8 0.0137 0.0596 0.0924
Echinococcus granulosus tyrosine protein kinase Lyn 0.0009 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0122 0.01
Echinococcus granulosus flap endonuclease GEN 1 0.0011 0.0011 0.0018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0006 0.0007
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0639 0.1381
Plasmodium vivax histone deacetylase, putative 0.0137 0.0596 0.0591
Echinococcus granulosus fmrfamide receptor 0.0032 0.0109 0.017
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0109 0.0144
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0263 0.118 0.1831
Schistosoma mansoni dishevelled 0.0009 0.0003 0.0004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0109 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.01 0.021
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.0007 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0118 0.0507 0.0804
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0027 0.0052
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0519 0.1122
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0171 0.0844
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0007 0.0016
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0161 0.016
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0122 0.031
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0009 0.0014
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0118 0.0507 0.0486
Brugia malayi hypothetical protein 0.0049 0.0191 0.0408
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0027 0.0042
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0117 0.0504 0.0798
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0035 0.0046
Brugia malayi nuclear hormone receptor 0.003 0.01 0.021
Onchocerca volvulus 0.0032 0.0109 0.0995
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0109 0.0144
Echinococcus granulosus expressed conserved protein 0.0187 0.0831 0.1289
Onchocerca volvulus 0.0032 0.0109 0.0995
Loa Loa (eye worm) oxidoreductase 0.0035 0.0122 0.0258
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0109 0.0995
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0109 0.0144
Brugia malayi histone deacetylase 1 (HD1) 0.0277 0.1245 0.2698
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0133 0.0339
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Giardia lamblia DNA damage repair protein 0.0029 0.0095 0.0498
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0624 0.1603
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0219 0.056
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0109 0.0144
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0099 0.0421 0.108
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.0012 0.0085
Echinococcus granulosus insulin receptor 0.0321 0.1451 0.2251
Echinococcus granulosus g protein coupled receptor 0.0032 0.0109 0.017
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.047 0.2356
Echinococcus multilocularis FTZ F1 alpha 0.003 0.01 0.0132
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0012 0.0017
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.005 0.0027
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0109 0.017
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0035 0.0122 0.0203
Schistosoma mansoni DNA polymerase IV / kappa 0.0029 0.0095 0.0146
Loa Loa (eye worm) hypothetical protein 0.0152 0.0668 0.1443
Plasmodium falciparum glutathione reductase 0.0038 0.0137 0.0136
Brugia malayi RNA, U transporter 1 0.0084 0.0349 0.0751
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.0069
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0099 0.0421 0.0815
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0003 0.0005
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0035 0.0122 0.01
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0049 0.0191 0.0144
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.0011 0.001
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0099 0.0098
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Schistosoma mansoni hypothetical protein 0.0081 0.0335 0.0519
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Brugia malayi Serotonin receptor 0.0032 0.0109 0.0231
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.0012 0.0033
Leishmania major 4-coumarate:coa ligase-like protein 0.0118 0.0507 0.1301
Entamoeba histolytica hypothetical protein 0.0043 0.0162 0.1288
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0136 0.1087
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0109 0.017
Brugia malayi sulfakinin receptor protein 0.0032 0.0109 0.0231
Brugia malayi ecdysone receptor 0.0014 0.0027 0.0052
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0362 0.0694
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0133 0.0339
Giardia lamblia Casein kinase II beta chain 0.0037 0.0133 0.0709
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.014 0.0184
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0122 0.0258
Schistosoma mansoni histamine h1 receptor 0.0032 0.0109 0.0169
Onchocerca volvulus 0.0069 0.0281 0.26
Giardia lamblia Kinase, CMGC CDK 0.0045 0.0171 0.0924
Toxoplasma gondii histone deacetylase HDAC1 0.0325 0.1467 0.1466
Brugia malayi hypothetical protein 0.0012 0.0018 0.0032
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.01 0.0154
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0095 0.0241
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.0789 0.1224
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0035 0.0053
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.005 0.0389
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0012 0.0017
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0434 0.1976 0.4284
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0349 0.054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0035 0.007
Trichomonas vaginalis set domain proteins, putative 0.0239 0.1071 0.541
Echinococcus granulosus Niemann Pick C1 protein 0.02 0.0887 0.1376
Echinococcus granulosus histone deacetylase 0.0325 0.1467 0.2276
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.01 0.021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0144 0.0143
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0255 0.1142 0.2473
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0027 0.0035
Echinococcus granulosus BC026374 protein S09 family 0.0069 0.0281 0.0436
Schistosoma mansoni cell adhesion molecule 0.0016 0.0035 0.0053
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0109 0.0169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0109 0.0169
Echinococcus granulosus hypothetical protein 0.0032 0.0109 0.017
Onchocerca volvulus 0.0239 0.1071 1
Plasmodium falciparum protein kinase 5 0.0045 0.0171 0.017
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.031
Loa Loa (eye worm) hypothetical protein 0.003 0.01 0.021
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0244 0.0524
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0099 0.0476
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Echinococcus multilocularis exonuclease 1 0.0011 0.0011 0.0015
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0054 0.0084
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0009 0.0005 0.0032
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0035 0.0122 0.01
Loa Loa (eye worm) hypothetical protein 0.0088 0.0369 0.0795
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0133 0.0128
Loa Loa (eye worm) RNA binding protein 0.0076 0.0313 0.0674
Chlamydia trachomatis DNA ligase 0.0049 0.0191 0.0169
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0104 0.0161
Loa Loa (eye worm) hypothetical protein 0.0088 0.0369 0.0795
Plasmodium falciparum thioredoxin reductase 0.0013 0.0023 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.1362 0.35
Loa Loa (eye worm) patched family protein 0.0012 0.0018 0.0032
Onchocerca volvulus 0.0032 0.0109 0.0995
Plasmodium vivax protein kinase Crk2 0.0045 0.0171 0.0166
Onchocerca volvulus 0.0032 0.0109 0.0995
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0072 0.0183
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0109 0.017
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0027 0.0042
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0109 0.0169
Echinococcus multilocularis expressed protein 0.0032 0.0112 0.0148
Brugia malayi conserved hypotetical protein 0.0014 0.0027 0.0052
Brugia malayi Patched family protein 0.0012 0.0018 0.0032
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0005 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0313 0.0674
Loa Loa (eye worm) RecQ helicase 0.002 0.0054 0.0112
Echinococcus multilocularis acetylcholinesterase 0.0407 0.185 0.244
Echinococcus granulosus flap endonuclease 1 0.0053 0.0205 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0191 0.0488
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.005 0.0101
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0349 0.0751
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0219 0.056
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0109 0.0231
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0104 0.0161
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0045 0.0171 0.0366
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0133 0.1058
Loa Loa (eye worm) hypothetical protein 0.0407 0.185 0.401
Leishmania major 4-coumarate:coa ligase-like protein 0.0118 0.0507 0.1301
Mycobacterium ulcerans glutaminase 0.0276 0.1239 0.1219
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0109 0.0169
Brugia malayi Steroid receptor seven-up type 2 0.003 0.01 0.021
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0109 0.0231
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0108 0.0107
Trypanosoma brucei unspecified product 0.0064 0.0257 0.0659
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0122 0.031
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.047 0.2356
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0035 0.007
Toxoplasma gondii patched family protein 0.0012 0.0018 0.0017
Schistosoma mansoni histone deacetylase 4 5 0.0325 0.1467 0.2276
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.005 0.0055
Toxoplasma gondii exonuclease III APE 0.0019 0.005 0.0048
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0301 0.1356 0.1336
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0122 0.031
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0263 0.118 0.1557
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0109 0.0144
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0008
Onchocerca volvulus 0.0032 0.0109 0.0995
Plasmodium falciparum glutathione reductase 0.0013 0.0023 0.0021
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0023 0.0188
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trypanosoma brucei trypanothione reductase 0.0038 0.0137 0.035
Echinococcus granulosus nibrin 0.0049 0.0191 0.0296
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0023 0.0055
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0133 0.0648
Loa Loa (eye worm) hypothetical protein 0.0012 0.0018 0.0032
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0099 0.0476
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0249 0.1114 0.2412
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0349 0.0541
Trypanosoma brucei DNA repair protein RAD2, putative 0.0011 0.0011 0.0026
Trichomonas vaginalis histone deacetylase, putative 0.0277 0.1245 0.6294
Schistosoma mansoni nuclear receptor 0.0014 0.0027 0.0041
Schistosoma mansoni hypothetical protein 0.0081 0.0335 0.0519
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0244 0.0378
Onchocerca volvulus 0.0032 0.0109 0.0995
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Brugia malayi hypothetical protein 0.0069 0.0281 0.0603
Schistosoma mansoni biogenic amine receptor 0.0032 0.0109 0.0169
Echinococcus granulosus intestinal type alkaline phosphatase 0.0164 0.0721 0.112
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0281 0.0435
Loa Loa (eye worm) glutathione reductase 0.0038 0.0137 0.0291
Echinococcus multilocularis cyclin dependent kinase 1 0.0045 0.0171 0.0226
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0012 0.0017
Echinococcus granulosus histone deacetylase 6 0.0325 0.1467 0.2276
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.01 0.021
Brugia malayi hypothetical protein 0.0012 0.0018 0.0032
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0009 0.002
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0062 0.0061
Entamoeba histolytica Ran family GTPase 0.0022 0.0062 0.0489
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0255 0.0394
Brugia malayi neuropeptide F receptor 0.0032 0.0109 0.0231
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.047 0.1205
Loa Loa (eye worm) hypothetical protein 0.0098 0.0418 0.0901
Brugia malayi Protein kinase domain containing protein 0.0181 0.0802 0.1736
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0001 0.0001
Brugia malayi jmjC domain containing protein 0.0016 0.0035 0.007
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.0011 0.0026
Brugia malayi Carboxylesterase family protein 0.0069 0.0281 0.0603
Echinococcus multilocularis sterol regulatory element binding protein 0.0434 0.1976 0.2607
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.047 0.1013
Brugia malayi topoisomerase 0.0049 0.0191 0.0408
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0109 0.0144
Plasmodium vivax histone deacetylase 2, putative 0.0325 0.1467 0.1463
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Loa Loa (eye worm) hypothetical protein 0.0032 0.0109 0.0231
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0191 0.0488
Schistosoma mansoni cpg binding protein 0.0031 0.0105 0.0162

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.3 uM In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assay ChEMBL. 15780630
IC50 (functional) = 0.3 uM In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assay ChEMBL. 15780630
Ki (functional) = 0.36 uM Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP) ChEMBL. 15780630
Ki (functional) = 0.36 uM Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP) ChEMBL. 15780630

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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