Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | g protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0092 | 0.0092 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Onchocerca volvulus | 0.0025 | 0.0019 | 0.0116 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | carboxylesterase | 0.3851 | 1 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0043 | 0.0066 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | amine oxidase | 0.0043 | 0.0066 | 0.0066 |
Echinococcus granulosus | carboxylesterase 5A | 0.3851 | 1 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | acetylcholinesterase | 0.3851 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | g protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0043 | 0.0066 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Choline O-acetyltransferase | 0.0168 | 0.0393 | 0.0393 |
Onchocerca volvulus | 0.0025 | 0.0019 | 0.0116 | |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.0025 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | allatostatin A receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Serotonin receptor | 0.1428 | 0.3678 | 0.3678 |
Onchocerca volvulus | 0.0025 | 0.0019 | 0.0116 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0031 | 0.0031 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0031 | 0.0035 | 0.0213 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0043 | 0.0066 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Pre-SET motif family protein | 0.0214 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | carboxylesterase | 0.0651 | 0.1651 | 0.1651 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0034 | 0.0034 |
Schistosoma mansoni | gliotactin | 0.0651 | 0.1651 | 0.1651 |
Loa Loa (eye worm) | hypothetical protein | 0.0765 | 0.1949 | 0.1949 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | opsin-like receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0025 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.3851 | 1 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.0025 | 0.0019 | 0.0019 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0043 | 0.0066 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3851 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.1496 | 0.3857 | 0.3857 |
Trichomonas vaginalis | set domain proteins, putative | 0.0244 | 0.0589 | 0.3567 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0049 | 0.0049 |
Echinococcus multilocularis | conserved hypothetical protein | 0.2094 | 0.5417 | 0.5417 |
Brugia malayi | RE15519p | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | acetylcholinesterase | 0.3851 | 1 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | fmrfamide receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.3851 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0651 | 0.1651 | 0.1651 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Serotonin receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | sex peptide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | larval opioid receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0651 | 0.1651 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Choline O-acetyltransferase | 0.0168 | 0.0393 | 0.0393 |
Echinococcus granulosus | hypothetical protein | 0.2126 | 0.5499 | 0.5499 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0568 | 0.1434 | 0.8633 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0034 | 0.5113 |
Brugia malayi | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0038 | 0.0052 | 0.0052 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0066 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.0168 | 0.0393 | 0.0393 |
Onchocerca volvulus | 0.0651 | 0.1651 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0043 | 0.0066 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Schistosoma mansoni | amine GPCR | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Carboxylesterase family protein | 0.0651 | 0.1651 | 0.1651 |
Echinococcus multilocularis | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Echinococcus granulosus | neuropeptide s receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0066 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0039 | 0.0039 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3851 | 1 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Carboxylesterase family protein | 0.0651 | 0.1651 | 0.1651 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0651 | 0.1651 | 1 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0043 | 0.0066 | 0.0066 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0043 | 0.0066 | 0.5 |
Brugia malayi | G-protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0041 | 0.0062 | 0.0062 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0043 | 0.0066 | 0.0066 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0043 | 0.0066 | 0.0066 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | 0.0043 | 0.0066 | 0.0066 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0031 | 0.0035 | 0.0035 |
Leishmania major | C-8 sterol isomerase-like protein | 0.1496 | 0.3857 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0034 | 0.0034 |
Schistosoma mansoni | myosin xvIII | 0.0031 | 0.0035 | 0.0035 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.1496 | 0.3857 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0043 | 0.0066 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0043 | 0.0066 | 0.0066 |
Brugia malayi | neuropeptide F receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0025 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | AKH receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | choline o-acyltransferase | 0.0168 | 0.0393 | 0.0393 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuroligin | 0.0651 | 0.1651 | 0.1651 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0046 | 0.0278 |
Brugia malayi | Carboxylesterase family protein | 0.3851 | 1 | 1 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | putative neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0244 | 0.0589 | 0.3567 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Schistosoma mansoni | adenoreceptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0043 | 0.0066 | 0.0066 |
Schistosoma mansoni | histamine h1 receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0025 | 0.0019 | 0.0019 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0049 | 0.0049 |
Echinococcus granulosus | somatostatin receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Dopamine receptor protein 1 | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | neuropeptide F receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0031 | 0.0035 | 0.0035 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0034 | 0.5113 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0034 | 0.0034 |
Brugia malayi | GnHR receptor homolog | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | opsin-like receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | G protein-coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | g protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0031 | 0.0035 | 0.0035 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0049 | 0.5 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | amine GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0168 | 0.0393 | 0.0393 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | G-protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0611 | 0.1547 | 0.9341 |
Brugia malayi | Dopamine receptor protein 2 | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Echinococcus granulosus | acetylcholinesterase | 0.3851 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.3851 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | biogenic amine receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0043 | 0.0066 | 0.0066 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | g protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0035 | 0.0046 | 0.0278 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0043 | 0.0066 | 1 |
Schistosoma mansoni | amine GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | fmrfamide receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | g-protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | allatostatin A receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0034 | 0.0034 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0031 | 0.0035 | 0.0035 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0049 | 0.5 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0049 | 0.0049 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0611 | 0.1547 | 0.9341 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0041 | 0.0062 | 0.0062 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0651 | 0.1651 | 0.1651 |
Brugia malayi | Carboxylesterase family protein | 0.0651 | 0.1651 | 0.1651 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0034 | 0.0034 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0049 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0049 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Schistosoma mansoni | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | biogenic amine receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0651 | 0.1651 | 0.1651 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0034 | 0.0034 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0651 | 0.1651 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | serotonin receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0043 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | sex peptide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0651 | 0.1651 | 0.1651 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0025 | 0.0019 | 0.0019 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0651 | 0.1651 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.1496 | 0.3857 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0168 | 0.0393 | 0.0393 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0043 | 0.0066 | 0.0121 |
Brugia malayi | Melatonin receptor type 1A | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0038 | 0.0052 | 0.0052 |
Schistosoma mansoni | amine oxidase | 0.0043 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Dopamine receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0025 | 0.0019 | 0.0019 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0038 | 0.0052 | 0.0052 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0031 | 0.0035 | 0.0213 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0034 | 0.0034 |
Brugia malayi | sulfakinin receptor protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | choline o-acyltransferase | 0.0025 | 0.0019 | 0.0019 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0025 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0038 | 0.0052 | 0.0052 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | SWIRM domain containing protein | 0.0043 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3851 | 1 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0393 | 0.0393 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0651 | 0.1651 | 0.1651 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | carboxylesterase | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0444 | 0.1111 | 0.1111 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0214 | 0.0512 | 0.0512 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0025 | 0.0019 | 0.0019 |
Leishmania major | UDP-galactopyranose mutase | 0.0043 | 0.0066 | 0.0121 |
Onchocerca volvulus | 0.0651 | 0.1651 | 1 | |
Brugia malayi | ORL1-like opioid receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | orexin receptor type 2 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Carboxylesterase family protein | 0.0651 | 0.1651 | 0.1651 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | follicle stimulating hormone receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | biogenic amine receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | serotonin receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0651 | 0.1651 | 1 | |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0043 | 0.0066 | 1 |
Onchocerca volvulus | 0.0025 | 0.0019 | 0.0116 | |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0043 | 0.0066 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0034 | 0.0034 |
Echinococcus granulosus | neuropeptide receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0651 | 0.1651 | 0.1651 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0651 | 0.1651 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | amine GPCR | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Schistosoma mansoni | acetylcholinesterase | 0.0651 | 0.1651 | 0.1651 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0034 | 0.0204 | |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0031 | 0.0035 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Echinococcus multilocularis | somatostatin receptor | 0.0031 | 0.0035 | 0.0035 |
Echinococcus granulosus | fmrfamide receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.1496 | 0.3857 | 0.3857 |
Echinococcus granulosus | neuroligin | 0.0651 | 0.1651 | 0.1651 |
Echinococcus granulosus | serotonin receptor | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0035 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.0031 | 0.0035 | 0.0213 | |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0031 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0066 | 0.0066 |
Onchocerca volvulus | 0.0651 | 0.1651 | 1 | |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0651 | 0.1651 | 1 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0031 | 0.0035 | 0.0035 |
Onchocerca volvulus | 0.0043 | 0.0066 | 0.0398 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0031 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0651 | 0.1651 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0031 | 0.0035 | 0.0035 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | > 100 uM | Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages | ChEMBL. | 15780639 |
IC50 (functional) | > 100 uM | Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages | ChEMBL. | 15780639 |
Inhibition (functional) | = 25 % | Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound | ChEMBL. | 15780639 |
Inhibition (functional) | = 25 % | Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound | ChEMBL. | 15780639 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.