Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1876 | 0.3129 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1876 | 0.3129 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0569 | 0.0791 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0086 | 0.248 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Echinococcus multilocularis | thymidylate synthase | 0.0105 | 0.3143 | 0.5397 |
Schistosoma mansoni | coup transcription factor | 0.0181 | 0.5716 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0043 | 0.1039 | 0.1631 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.1876 | 0.2922 |
Onchocerca volvulus | 0.023 | 0.7363 | 1 | |
Mycobacterium ulcerans | thymidylate synthase | 0.0105 | 0.3143 | 1 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1876 | 0.3129 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus multilocularis | leucine rich repeat serine:threonine protein | 0.0126 | 0.384 | 0.6643 |
Echinococcus granulosus | thymidylate synthase | 0.0105 | 0.3143 | 0.5397 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.1141 | 0.2271 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.3129 | 0.8411 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | thymidylate synthase | 0.0105 | 0.3143 | 0.2908 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0086 | 0.248 | 0.4209 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.004 | 0.0944 | 0.146 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.4593 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.4593 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0086 | 0.248 | 0.2221 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0181 | 0.5716 | 0.8904 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0497 | 0.0511 |
Brugia malayi | glutathione reductase | 0.0046 | 0.1141 | 0.1778 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0181 | 0.5716 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.128 | 0.1593 |
Brugia malayi | ecdysteroid receptor | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.1141 | 0.2271 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.3524 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0086 | 0.248 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0096 | 0.2826 | 0.4829 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0181 | 0.5716 | 0.5569 |
Brugia malayi | nuclear receptor NHR-88 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.1141 | 0.1814 |
Brugia malayi | hypothetical protein | 0.0096 | 0.2826 | 0.4403 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0181 | 0.5716 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.3129 | 0.8837 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0569 | 0.0791 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0969 | 0.1163 |
Brugia malayi | nuclear receptor RXR | 0.0086 | 0.248 | 0.3863 |
Schistosoma mansoni | zinc finger protein | 0.0086 | 0.248 | 0.4209 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0086 | 0.248 | 0.2221 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0569 | 0.099 |
Brugia malayi | tailless protein | 0.0086 | 0.248 | 0.3863 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1287 | 0.2075 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Onchocerca volvulus | 0.0086 | 0.248 | 0.2785 | |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0181 | 0.5716 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0871 | 0.0409 |
Brugia malayi | hypothetical protein | 0.0096 | 0.2826 | 0.4403 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0969 | 0.1163 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0181 | 0.5716 | 0.5569 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0086 | 0.248 | 0.4209 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.005 | 0.128 | 0.2582 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0043 | 0.1039 | 0.0731 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1876 | 0.3129 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.1141 | 0.2271 |
Brugia malayi | nuclear receptor NHR-67 | 0.0086 | 0.248 | 0.3863 |
Brugia malayi | nuclear receptor NHR-88 | 0.0086 | 0.248 | 0.3863 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Leishmania major | trypanothione reductase | 0.0046 | 0.1141 | 0.2271 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.3524 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.3129 | 0.8837 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.1141 | 0.0837 |
Brugia malayi | hypothetical protein | 0.0086 | 0.248 | 0.3863 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0127 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0871 | 0.1028 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0181 | 0.5716 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.3524 | 1 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0086 | 0.248 | 0.3863 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0096 | 0.2826 | 0.4403 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Brugia malayi | nuclear receptor RXR | 0.0096 | 0.2826 | 0.4403 |
Brugia malayi | ecdysone receptor | 0.0086 | 0.248 | 0.3863 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0086 | 0.248 | 0.3863 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0043 | 0.1039 | 0.2683 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0127 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.023 | 0.7363 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0181 | 0.5716 | 0.5569 |
Brugia malayi | conserved hypotetical protein | 0.0086 | 0.248 | 0.3863 |
Brugia malayi | hypothetical protein | 0.005 | 0.128 | 0.1995 |
Echinococcus granulosus | leucine rich repeat serine:threonine protein | 0.0127 | 0.3869 | 0.6695 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0332 | 0.0517 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0086 | 0.248 | 0.2221 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0181 | 0.5716 | 0.8904 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0181 | 0.5716 | 0.7567 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0181 | 0.5716 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0086 | 0.248 | 0.2785 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0086 | 0.248 | 0.4209 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0105 | 0.3143 | 0.8879 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.3129 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2826 | 0.258 |
Brugia malayi | thymidylate synthase | 0.0105 | 0.3143 | 0.4897 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.3524 | 1 |
Onchocerca volvulus | 0.004 | 0.0944 | 0.0516 | |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.3129 | 0.8837 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0127 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2826 | 0.258 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0969 | 0.0553 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0086 | 0.248 | 0.3863 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.3129 | 0.8837 |
Schistosoma mansoni | nuclear receptor | 0.0086 | 0.248 | 0.4209 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0594 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0181 | 0.5716 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0086 | 0.248 | 0.4209 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0181 | 0.5716 | 0.5569 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0181 | 0.5716 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0096 | 0.2826 | 0.4829 |
Brugia malayi | hypothetical protein | 0.0118 | 0.3584 | 0.5583 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0086 | 0.248 | 0.2221 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.6419 | 0.6296 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0181 | 0.5716 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0181 | 0.5716 | 0.5569 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0497 | 0.0511 |
Brugia malayi | Protein kinase domain containing protein | 0.0126 | 0.384 | 0.5982 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0016 | 0.0127 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0181 | 0.5716 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0871 | 0.1357 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0086 | 0.248 | 0.3863 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0096 | 0.2826 | 0.4829 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0181 | 0.5716 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0181 | 0.5716 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0086 | 0.248 | 0.2785 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0086 | 0.248 | 0.4209 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0569 | 0.099 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.1141 | 0.2271 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0181 | 0.5716 | 0.7567 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0181 | 0.5716 | 0.5569 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0181 | 0.5716 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0569 | 0.0791 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.1876 | 0.1597 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0096 | 0.2826 | 0.4829 |
Brugia malayi | steroid hormone receptor | 0.0181 | 0.5716 | 0.8904 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.4593 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0181 | 0.5716 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | TKL/LRRK protein kinase | 0.0126 | 0.384 | 0.3628 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1876 | 0.3129 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0533 | 0.0726 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0181 | 0.5716 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0569 | 0.0245 |
Echinococcus granulosus | FTZ F1 alpha | 0.0181 | 0.5716 | 1 |
Mycobacterium tuberculosis | Hypothetical protein | 0.005 | 0.128 | 0.3394 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0043 | 0.1039 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0086 | 0.248 | 0.4209 |
Onchocerca volvulus | 0.0105 | 0.3143 | 0.3766 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0181 | 0.5716 | 0.5569 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0086 | 0.248 | 0.4209 |
Brugia malayi | hypothetical protein | 0.0086 | 0.248 | 0.3863 |
Schistosoma mansoni | nuclear hormone receptor | 0.0086 | 0.248 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.5716 | 0.5569 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0181 | 0.5716 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0569 | 0.0887 |
Echinococcus granulosus | dihydrofolate reductase | 0.0043 | 0.1039 | 0.1631 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0086 | 0.248 | 0.4209 |
Brugia malayi | Dihydrofolate reductase | 0.0043 | 0.1039 | 0.1618 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0127 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0181 | 0.5716 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0181 | 0.5716 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0181 | 0.5716 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.6419 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.1141 | 0.1778 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0871 | 0.0558 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.1141 | 0.1814 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0569 | 0.0791 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0096 | 0.2826 | 0.258 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.3129 | 0.8837 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.1141 | 0.2271 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2826 | 0.258 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0086 | 0.248 | 0.4209 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0086 | 0.248 | 0.3863 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1876 | 0.3129 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.4593 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0569 | 0.0791 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0181 | 0.5716 | 0.7567 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0105 | 0.3143 | 0.8468 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0086 | 0.248 | 0.4209 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1876 | 0.2417 |
Onchocerca volvulus | 0.0181 | 0.5716 | 0.7567 | |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0043 | 0.1039 | 0.3022 |
Schistosoma mansoni | thyroid hormone receptor | 0.0181 | 0.5716 | 1 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0105 | 0.3143 | 0.5397 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0148 | 0.4593 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0086 | 0.248 | 0.4209 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0086 | 0.248 | 0.3863 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.1141 | 0.0837 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0181 | 0.5716 | 0.8904 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0181 | 0.5716 | 0.5569 |
Brugia malayi | nuclear hormone receptor | 0.0086 | 0.248 | 0.3863 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0096 | 0.2826 | 0.4403 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0181 | 0.5716 | 0.8904 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0569 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2826 | 0.258 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0181 | 0.5716 | 0.8904 |
Schistosoma mansoni | nuclear receptor | 0.0086 | 0.248 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.248 | 0.2221 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.1141 | 0.2985 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0148 | 0.4593 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1876 | 0.2417 |
Brugia malayi | dihydrofolate reductase family protein | 0.0043 | 0.1039 | 0.1618 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0086 | 0.248 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.2826 | 0.258 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.1141 | 0.2271 |
Brugia malayi | nuclear hormone receptor | 0.0181 | 0.5716 | 0.8904 |
Onchocerca volvulus | 0.0086 | 0.248 | 0.2785 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0871 | 0.1028 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.1141 | 0.2271 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0086 | 0.248 | 0.4209 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0086 | 0.248 | 0.4209 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0181 | 0.5716 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0181 | 0.5716 | 1 |
Schistosoma mansoni | dihydrofolate reductase | 0.0043 | 0.1039 | 0.1631 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 87 uM | Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of hepatitis C virus | ChEMBL. | 15664835 |
IC50 (binding) | = 87 uM | Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of hepatitis C virus | ChEMBL. | 15664835 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.