Detailed information for compound 319961

Basic information

Technical information
  • TDR Targets ID: 319961
  • Name: N-(3,4-difluorophenyl)-4-[2-(4-fluorophenyl)- 6-methylpyrazolo[5,1-f]pyridazin-3-yl]pyrimid in-2-amine
  • MW: 432.401 | Formula: C23H15F3N6
  • H donors: 1 H acceptors: 4 LogP: 4.81 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)c1nn2c(c1c1ccnc(n1)Nc1ccc(c(c1)F)F)ccc(n2)C
  • InChi: 1S/C23H15F3N6/c1-13-2-9-20-21(22(31-32(20)30-13)14-3-5-15(24)6-4-14)19-10-11-27-23(29-19)28-16-7-8-17(25)18(26)12-16/h2-12H,1H3,(H,27,28,29)
  • InChiKey: CYHPFZLFUXOCJJ-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(3,4-difluorophenyl)-4-[2-(4-fluorophenyl)-6-methyl-pyrazolo[5,1-f]pyridazin-3-yl]pyrimidin-2-amine
  • N-(3,4-difluorophenyl)-4-[2-(4-fluorophenyl)-6-methyl-3-pyrazolo[5,1-f]pyridazinyl]-2-pyrimidinamine
  • (3,4-difluorophenyl)-[4-[2-(4-fluorophenyl)-6-methyl-pyrazolo[5,1-f]pyridazin-3-yl]pyrimidin-2-yl]amine
  • pyrazolo[1,5-b]pyridazine deriv. 100

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glycogen synthase kinase 3 beta Starlite/ChEMBL References
Homo sapiens cyclin-dependent kinase 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Theileria parva glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium knowlesi Cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania braziliensis cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC GSK Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium knowlesi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium parvum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania mexicana cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi intracellular kinase Get druggable targets OG5_126888 All targets in OG5_126888
Giardia lamblia Kinase, CMGC CDK Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans Serine/threonine protein kinase required for induction of IME2 by Ime1p Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium hominis hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania mexicana protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma congolense cdc2-related kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Neospora caninum hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Onchocerca volvulus Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania mexicana cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium falciparum protein kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Plasmodium falciparum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cdc2-related kinase 3, putative Get druggable targets OG5_126712 All targets in OG5_126712
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Babesia bovis cell division control protein 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 5 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani cell division protein kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans hypothetical protein Get druggable targets OG5_126888 All targets in OG5_126888
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126712 All targets in OG5_126712
Candida albicans second truncated form of RIM11 Serine/threonine protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania infantum cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus multilocularis cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K08822 glycogen synthase kinase 3 alpha, putative Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus glycogen synthase kinase 3 beta Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium parvum Cdc2-like CDK2/CDC28 like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 1 Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Babesia bovis protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Loa Loa (eye worm) CMGC/GSK protein kinase Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium berghei glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Neospora caninum CMGC kinase, CDK family TgPK2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania infantum glycogen synthase kinase 3 Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense cell division protein kinase 2 homolog 1,cdc2- like protein kinase, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Cryptosporidium hominis cdc2-like protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02087 cyclin-dependent kinase 1, putative Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica protein kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania braziliensis cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania major cell division related protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus cyclin dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126712 All targets in OG5_126712
Echinococcus granulosus protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Echinococcus multilocularis protein kinase shaggy Get druggable targets OG5_126888 All targets in OG5_126888
Theileria parva cell division control protein 2 related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Leishmania donovani glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888
Brugia malayi cell division control protein 2 homolog Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi cdc2-related kinase 3 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) Get druggable targets OG5_126888 All targets in OG5_126888
Entamoeba histolytica protein kinase domain containing protein Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania infantum cell division protein kinase 2,cdc2-related kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma brucei gambiense cell division related protein kinase 2, putative,CDC2-related protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Entamoeba histolytica cell division protein kinase 2, putative Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii Protein kinase domain, putative Get druggable targets OG5_126888 All targets in OG5_126888
Trypanosoma brucei gambiense protein kinase, putative,glycogen synthase kinase, putative Get druggable targets OG5_126888 All targets in OG5_126888
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 Get druggable targets OG5_126888 All targets in OG5_126888
Candida albicans Protein kinase that can substitute for S. cerevisiae CDC28 (YBR160W) main cell cycle cyclin-dependent kinase Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium vivax protein kinase Crk2 Get druggable targets OG5_126712 All targets in OG5_126712
Plasmodium yoelii cdc2-related kinase 2 Get druggable targets OG5_126712 All targets in OG5_126712
Schistosoma japonicum ko:K02090 cyclin-dependent kinase 5, putative Get druggable targets OG5_126712 All targets in OG5_126712
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126712 All targets in OG5_126712
Trypanosoma cruzi glycogen synthase kinase 3, putative Get druggable targets OG5_126888 All targets in OG5_126888

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 cyclin-dependent kinase 3 305 aa 303 aa 32.0 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis Immunoglobulin 0.0016 0.0022 0.0049
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0075 0.0069
Onchocerca volvulus 0.0012 0.0014 0.0191
Brugia malayi Calcitonin receptor-like protein seb-1 0.025 0.0603 0.5457
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0017 0.0026 0.0213
Onchocerca volvulus 0.0031 0.006 0.0995
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0057 0.0854
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0008 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0132 0.1984
Brugia malayi protein C24B5.3 0.0012 0.0014 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0055 0.0658
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0057 0.0953
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0018 0.0039
Plasmodium falciparum histone deacetylase 1 0.0268 0.0646 0.064
Echinococcus multilocularis roundabout 2 0.0016 0.0022 0.0049
Brugia malayi Histone deacetylase 1 0.0268 0.0646 0.5847
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0068
Schistosoma mansoni DNA polymerase eta 0.0118 0.0276 0.0794
Brugia malayi jmjC domain containing protein 0.0059 0.013 0.1161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Loa Loa (eye worm) hypothetical protein 0.0088 0.0201 0.1805
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0605
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0234 0.0564 0.0549
Brugia malayi hypothetical protein 0.0057 0.0125 0.1116
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Schistosoma mansoni hypothetical protein 0.0079 0.018 0.0514
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0035 0.0069 0.0053
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0561 0.1371 0.3975
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trypanosoma cruzi DNA polymerase eta, putative 0.0118 0.0276 0.3588
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0132 0.2012
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0096 0.0222 0.0217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0057 0.0497
Plasmodium vivax replication factor C subunit 1, putative 0.0049 0.0104 0.0098
Echinococcus multilocularis expressed conserved protein 0.0187 0.0448 0.1099
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0018 0.0039
Echinococcus granulosus smad 0.0008 0.0004 0.0004
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0121 0.0283 0.0814
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0119 0.0279 0.4189
Onchocerca volvulus 0.0152 0.0361 0.6242
Trichomonas vaginalis flap endonuclease-1, putative 0.0053 0.0114 0.1709
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Schistosoma mansoni topbp1 0.0049 0.0104 0.0294
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Echinococcus multilocularis BC026374 protein (S09 family) 0.0057 0.0125 0.0303
Loa Loa (eye worm) hypothetical protein 0.0452 0.1103 1
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Toxoplasma gondii histone deacetylase HDAC5 0.0132 0.0311 0.0305
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0033 0.0277
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0023 0.0059
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0004 0.0004
Schistosoma mansoni cpg binding protein 0.0029 0.0056 0.0155
Loa Loa (eye worm) hypothetical protein 0.0083 0.019 0.1705
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0018 0.0046
Loa Loa (eye worm) acetylcholinesterase 1 0.0339 0.0822 0.7451
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0018 0.0046
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.001 0.0151
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0009 0.0006 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.001 0.0067
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0255 0.0623
Echinococcus multilocularis neuroglian 0.0016 0.0022 0.0049
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0255 0.0517
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0043 0.0639
Schistosoma mansoni thyroid hormone receptor 0.003 0.0057 0.0159
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0075 0.1125
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.019 0.0463
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0016 0.001
Trypanosoma brucei histone deacetylase, putative 0.0314 0.076 1
Brugia malayi phosphofructokinase 0.011 0.0255 0.2292
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.001 0.0004
Toxoplasma gondii patched family protein 0.0012 0.0014 0.0008
Echinococcus granulosus tumor protein p63 0.0672 0.1647 0.4776
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.0279 0.0263
Echinococcus granulosus glycogen synthase kinase 3 beta 0.006 0.0132 0.0376
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.018 0.0437
Trichomonas vaginalis DNA polymerase eta, putative 0.0119 0.0279 0.4189
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0337 0.4402
Schistosoma mansoni histone deacetylase 4 5 0.0314 0.076 0.2201
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0104 0.1559
Brugia malayi steroid hormone receptor 0.003 0.0057 0.0497
Echinococcus granulosus flap endonuclease 1 0.0053 0.0114 0.0323
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.006 0.0166
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0037 0.0075 0.0069
Onchocerca volvulus 0.0057 0.0125 0.214
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus multilocularis histone deacetylase 1 0.0268 0.0646 0.1589
Giardia lamblia DNA damage repair protein 0.0029 0.0055 0.0756
Brugia malayi hypothetical protein 0.0012 0.0014 0.01
Schistosoma mansoni glutaminase 0.0276 0.0666 0.1926
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0018 0.0046
Brugia malayi Latrophilin receptor protein 2 0.0079 0.018 0.1609
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0121 0.1551
Loa Loa (eye worm) hypothetical protein 0.007 0.0157 0.1404
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0018 0.0143
Mycobacterium ulcerans hypothetical protein 0.0159 0.0377 0.0362
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0221 0.0449
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0022 0.0181
Brugia malayi AMP-binding enzyme family protein 0.0118 0.0275 0.2475
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0035 0.0069 0.0193
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0077 0.0183
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0081 0.122
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0064 0.0958
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0057 0.0051
Onchocerca volvulus 0.0012 0.0014 0.0191
Brugia malayi TAR-binding protein 0.007 0.0157 0.1402
Schistosoma mansoni dep domain containing protein 0.0009 0.0006 0.0009
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0037 0.0075 0.0927
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0112 0.1414
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0023 0.0059
Chlamydia trachomatis DNA ligase 0.0049 0.0104 0.0088
Echinococcus multilocularis tumor protein p63 0.0672 0.1647 0.4061
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0037 0.0075 0.0944
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0008 0.004
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0016 0.0022 0.0058
Schistosoma mansoni hypothetical protein 0.0079 0.018 0.0514
Schistosoma mansoni hypothetical protein 0.0083 0.0188 0.0538
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0062 0.0754
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0023 0.0183
Schistosoma mansoni hypothetical protein 0.0314 0.076 0.22
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.006 0.0166
Schistosoma mansoni hypothetical protein 0.0083 0.019 0.0545
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.001 0.0151
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.009 0.0084
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0008 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0035 0.0069 0.0053
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0118 0.0275 0.0424
Echinococcus multilocularis replication factor c subunit 1 0.0049 0.0104 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0057 0.0497
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0035 0.0069 0.0053
Trypanosoma brucei histone deacetylase 4 0.0314 0.076 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0118 0.0275 0.0259
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.092
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0057 0.0159
Echinococcus granulosus histone deacetylase 1 0.0268 0.0646 0.1869
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0006 0.0011
Loa Loa (eye worm) RecQ helicase 0.002 0.0033 0.0277
Echinococcus granulosus nibrin 0.0049 0.0104 0.0294
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0009 0.0051
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0069 0.0849
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0016 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0057 0.0497
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0062 0.0771
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0033 0.0277
Toxoplasma gondii propionate-CoA ligase 0.0035 0.0069 0.0064
Loa Loa (eye worm) XPG I-region family protein 0.0011 0.001 0.0068
Schistosoma mansoni hypothetical protein 0.0079 0.018 0.0514
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0016 0.001
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0057 0.0159
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0018 0.0046
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0075 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Brugia malayi Patched related family protein 12 0.0012 0.0014 0.01
Plasmodium vivax protein kinase Crk2 0.0096 0.0222 0.0216
Trypanosoma cruzi FHA domain containing protein, putative 0.0049 0.0104 0.1308
Giardia lamblia Flap structure-specific endonuclease 0.0053 0.0114 0.168
Schistosoma mansoni DNA helicase recq5 0.002 0.0033 0.0088
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0339 0.0822 0.2381
Toxoplasma gondii histone deacetylase HDAC3 0.0268 0.0646 0.0641
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0057 0.0497
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0009 0.0018
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0049 0.0104 0.092
Schistosoma mansoni gliotactin 0.0057 0.0125 0.0357
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0197 0.0401
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0056 0.0697
Trypanosoma brucei DNA polymerase eta, putative 0.0118 0.0276 0.36
Toxoplasma gondii histone deacetylase HDAC2 0.0268 0.0646 0.0641
Loa Loa (eye worm) carboxylesterase 0.0057 0.0125 0.1116
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0197 0.0264
Brugia malayi 6-phosphofructokinase 0.011 0.0255 0.2292
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0033 0.0075
Schistosoma mansoni hypothetical protein 0.0327 0.0794 0.2299
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0335 0.0966
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0006 0.0011
Brugia malayi hypothetical protein 0.0009 0.0006 0.0027
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0018 0.0143
Plasmodium vivax exonuclease I, putative 0.0011 0.001 0.0004
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0182 0.0435 0.5704
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0003 0.0039
Echinococcus granulosus neuroligin 0.0057 0.0125 0.0357
Loa Loa (eye worm) histone deacetylase 0.0314 0.076 0.6887
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus multilocularis flap endonuclease GEN 1 0.0011 0.001 0.0018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0125 0.0357
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0018 0.0046
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0057 0.0854
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0057 0.0497
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0368 0.0894 1
Giardia lamblia Exonuclease 1 0.0011 0.001 0.0059
Giardia lamblia Kinase, CMGC GSK 0.006 0.0132 0.1966
Schistosoma mansoni patched 1 0.0086 0.0196 0.056
Echinococcus granulosus Niemann Pick C1 protein 0.0285 0.0689 0.1995
Loa Loa (eye worm) glutathione reductase 0.0038 0.0077 0.0679
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0057 0.0497
Entamoeba histolytica acyl-CoA synthetase, putative 0.0118 0.0275 0.4232
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0029 0.0055 0.0049
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0006 0.0036
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0092 0.0212 0.061
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0077 0.0216
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0057 0.0497
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0006 0.0034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0057 0.0159
Loa Loa (eye worm) pigment dispersing factor receptor c 0.025 0.0603 0.5457
Brugia malayi Carboxylesterase family protein 0.0339 0.0822 0.7451
Brugia malayi Pax transcription activation domain interacting protein 0.0049 0.0104 0.092
Echinococcus granulosus microtubule associated protein 2 0.1399 0.3445 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0057 0.0125 0.1883
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0134 0.1199
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0035 0.0069 0.014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0121 0.1076
Entamoeba histolytica protein kinase, putative 0.0182 0.0435 0.6725
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0255 0.392
Echinococcus multilocularis Niemann Pick C1 protein 0.0285 0.0689 0.1696
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.001 0.0067
Schistosoma mansoni vesicular amine transporter 0.0016 0.0022 0.0058
Echinococcus granulosus expressed protein 0.0032 0.0064 0.0178
Plasmodium vivax histone deacetylase 2, putative 0.0314 0.076 0.0755
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0075 0.0927
Brugia malayi nuclear receptor RXR 0.0016 0.0022 0.0181
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0425 0.1228
Toxoplasma gondii patched family protein 0.0012 0.0014 0.0008
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0255 0.3307
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0033 0.0277
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.02 0.0477 0.7382
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0134 0.0383
Schistosoma mansoni ap endonuclease 0.0019 0.0031 0.0081
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0006 0.0011
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.0337 0.4413
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.019 0.1705
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0132 0.0127
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0057 0.0159
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0182 0.0435 0.3932
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0077 0.0952
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0049 0.0104 0.1573
Plasmodium falciparum importin beta, putative 0.0029 0.0056 0.005
Brugia malayi Importin beta-1 subunit 0.0029 0.0056 0.0488
Giardia lamblia Histone deacetylase 0.0268 0.0646 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Brugia malayi MH2 domain containing protein 0.0008 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0077 0.0675
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus granulosus acetylcholinesterase 0.0339 0.0822 0.2381
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0077 0.0183
Loa Loa (eye worm) hypothetical protein 0.0171 0.0407 0.3676
Mycobacterium tuberculosis Carboxylesterase LipT 0.0057 0.0125 0.0254
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.025 0.0603 0.5457
Echinococcus multilocularis alkaline phosphatase 0.0164 0.0389 0.0955
Loa Loa (eye worm) hypothetical protein 0.0339 0.0822 0.7451
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0277
Brugia malayi Protein kinase domain containing protein 0.0182 0.0435 0.3932
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0229 0.2978
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0049 0.0104 0.0088
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Toxoplasma gondii exonuclease III APE 0.0019 0.0031 0.0025
Plasmodium falciparum DNA repair protein RAD2, putative 0.0011 0.001 0.0004
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0134 0.0383
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0268 0.0646 0.9705
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Toxoplasma gondii hypothetical protein 0.0012 0.0014 0.0008
Loa Loa (eye worm) hypothetical protein 0.0118 0.0275 0.2475
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trypanosoma brucei exonuclease, putative 0.0011 0.001 0.0086
Loa Loa (eye worm) hypothetical protein 0.0122 0.0284 0.2562
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0049 0.0104 0.1559
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0035 0.0069 0.0605
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0023 0.0253
Schistosoma mansoni cell adhesion molecule 0.0016 0.0022 0.0058
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Onchocerca volvulus 0.0035 0.0069 0.116
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0077 0.0183
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0069 0.0605
Entamoeba histolytica recQ family DNA helicase 0.001 0.0009 0.0097
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0006 0.0007
Echinococcus multilocularis Smad4 0.0008 0.0004 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0425 0.1228
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0031 0.0245
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0033 0.0027
Echinococcus multilocularis cpg binding protein 0.0031 0.006 0.0142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0043 0.0639
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0004 0.0005
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0006 0.0009
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0016 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Schistosoma mansoni histone deacetylase 0.0268 0.0646 0.1869
Onchocerca volvulus 0.0098 0.0227 0.3914
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Brugia malayi Thioredoxin reductase 0.0038 0.0077 0.0679
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0069 0.0605
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.018 0.0514
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0057 0.0051
Brugia malayi hypothetical protein 0.0016 0.0022 0.0181
Loa Loa (eye worm) acetyltransferase 0.0146 0.0345 0.3114
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0057 0.0497
Onchocerca volvulus 0.0012 0.0014 0.0191
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0022 0.0058
Brugia malayi Pre-SET motif family protein 0.0031 0.006 0.0519
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0057 0.0159
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0082 0.0196
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0009 0.0006 0.0018
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0008 0.0053
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0279 0.3637
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0646 0.9705
Entamoeba histolytica protein kinase domain containing protein 0.0182 0.0435 0.6725
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0037 0.0314
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1644 0.4052 1
Brugia malayi DKFZp564C0469 protein 0.0049 0.0104 0.092
Brugia malayi Carboxylesterase family protein 0.0339 0.0822 0.7451
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0031 0.0081
Schistosoma mansoni histone deacetylase hda2 0.0132 0.0311 0.0895
Brugia malayi MH2 domain containing protein 0.0008 0.0004 0.0012
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0016 0.0165
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0279 0.3625
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0077 0.1155
Echinococcus multilocularis muscleblind protein 0.0452 0.1103 0.2717
Echinococcus multilocularis dual specificity 0.0182 0.0435 0.1068
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.019 0.0463
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0016 0.001
Echinococcus granulosus defective proboscis extension response 0.0016 0.0022 0.0058
Echinococcus granulosus carboxylesterase 5A 0.0339 0.0822 0.2381
Schistosoma mansoni Smad4 0.0008 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Loa Loa (eye worm) TAR-binding protein 0.007 0.0157 0.1402
Brugia malayi histone deacetylase 1 (HD1) 0.0268 0.0646 0.5847
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0023 0.005
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0281 0.2534
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0069 0.0849
Plasmodium falciparum glycogen synthase kinase 3 0.006 0.0132 0.0126
Schistosoma mansoni acetylcholinesterase 0.0057 0.0125 0.0357
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0057 0.0159
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0033 0.0372
Brugia malayi tailless protein 0.0014 0.0018 0.0143
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0057 0.0159
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0255 0.0732
Brugia malayi N-terminal motif family protein 0.0181 0.0431 0.389
Echinococcus granulosus histone deacetylase 0.0314 0.076 0.2201
Echinococcus multilocularis casein kinase ii subunit beta 0.0037 0.0075 0.0179
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Brugia malayi hypothetical protein 0.004 0.0082 0.0722
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0037 0.0426
Loa Loa (eye worm) carboxylesterase 0.0057 0.0125 0.1116
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0189 0.0384
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.001 0.0004
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0053 0.0114 0.1456
Onchocerca volvulus 0.0057 0.0125 0.214
Echinococcus granulosus histone deacetylase 6 0.0314 0.076 0.2201
Onchocerca volvulus 0.0012 0.0014 0.0191
Echinococcus multilocularis tar DNA binding protein 0.007 0.0157 0.0381
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0057 0.0041
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0006 0.0009
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0022 0.0181
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0006 0.0034
Toxoplasma gondii patched family protein 0.0012 0.0014 0.0008
Leishmania major hypothetical protein, conserved 0.0026 0.0047 0.0559
Plasmodium vivax JmjC domain containing protein 0.0016 0.0023 0.0016
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0035 0.0069 0.0063
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0004 0.0003
Brugia malayi hypothetical protein 0.0049 0.0104 0.092
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0079 0.0221
Schistosoma mansoni ran 0.0022 0.0037 0.01
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0183
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.018 0.0429 0.3876
Loa Loa (eye worm) oxidoreductase 0.0035 0.0069 0.0605
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0254 0.0612 0.1505
Brugia malayi casein kinase II, putaitve 0.0011 0.001 0.007
Trypanosoma brucei histone deacetylase 1 0.0268 0.0646 0.8488
Trypanosoma brucei DNA repair protein RAD2, putative 0.0011 0.001 0.0086
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0009 0.0003
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0096 0.0222 0.1996
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0035 0.0069 0.1034
Loa Loa (eye worm) patched family protein 0.0012 0.0014 0.01
Brugia malayi histone deacetylase 3 (HD3) 0.0268 0.0646 0.5847
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0023 0.005
Echinococcus granulosus casein kinase ii subunit beta 0.0037 0.0075 0.021
Entamoeba histolytica hypothetical protein 0.004 0.0082 0.1234
Echinococcus granulosus protein kinase shaggy 0.006 0.0132 0.0376
Brugia malayi MH2 domain containing protein 0.012 0.0281 0.2534
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0057 0.0543
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.006 0.0132 0.1683
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0016 0.0022 0.0058
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0043 0.0639
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0057 0.0125 0.0357
Echinococcus granulosus GPCR family 2 0.0079 0.018 0.0514
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0006 0.0094
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0182 0.0435 0.5696
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0189 0.0384
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.0425 0.1228
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0031 0.0062
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0018 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0023 0.0183
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0053 0.0114 0.144
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0033 0.0088
Leishmania major importin beta-1 subunit, putative 0.0024 0.0043 0.0498
Mycobacterium ulcerans glutaminase 0.0276 0.0666 0.0651
Echinococcus multilocularis cyclin dependent kinase 1 0.0096 0.0222 0.0542
Brugia malayi jmjC domain containing protein 0.0016 0.0023 0.0183
Plasmodium vivax flap endonuclease 1, putative 0.0053 0.0114 0.0108
Leishmania major histone deacetylase, putative 0.0314 0.076 1
Trypanosoma brucei protein kinase, putative 0.006 0.0132 0.1698
Trichomonas vaginalis exonuclease%2C+putative 0.0011 0.001 0.0151
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0031 0.0254
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0345 0.3114
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0088 0.0201 0.0409
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0222 0.0638
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0057 0.0497
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0125 0.0357
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0035 0.0069 0.0605
Leishmania major DNA damage repair protein, putative 0.0029 0.0055 0.0658
Echinococcus granulosus exonuclease 1 0.0011 0.001 0.0022
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0016 0.0091
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0096 0.0222 0.1996
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0056 0.0486
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0268 0.0646 0.9705
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0092 0.0212 0.1907
Leishmania major hypothetical protein, conserved 0.0016 0.0023 0.0235
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Echinococcus granulosus dna polymerase kappa 0.0119 0.0279 0.0802
Brugia malayi Patched protein homolog 1 0.0012 0.0014 0.01
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0037 0.0031
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Schistosoma mansoni 3-dehydroquinate synthase 0.0234 0.0564 0.163
Echinococcus granulosus twitchin 0.0018 0.0029 0.0076
Echinococcus granulosus phd:f box containing protein 0.0016 0.0023 0.0059
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0035 0.0069 0.0053
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0023 0.0059
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0164 0.0389 0.1123
Brugia malayi Fibronectin type III domain containing protein 0.0016 0.0022 0.0181
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0023 0.0059
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0006 0.0027
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0018 0.0143
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0096 0.0222 0.2876
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0053 0.0114 0.0108
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0027
Leishmania major DNA polymerase kappa, putative 0.0099 0.0229 0.2965
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0075 0.1262
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.019 0.1705
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0006 0.0009
Brugia malayi nuclear receptor NHR-88 0.003 0.0057 0.0497
Onchocerca volvulus 0.0029 0.0056 0.0932
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0255 0.0383
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0077 0.0969
Brugia malayi Csnk2b protein 0.0037 0.0075 0.0658
Schistosoma mansoni nuclear hormone receptor 0.003 0.0057 0.0159
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.018 0.1609
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0018 0.0046
Loa Loa (eye worm) flap endonuclease-1 0.0053 0.0114 0.101
Onchocerca volvulus 0.0014 0.0018 0.0275
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0062 0.0754
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0092 0.0212 0.061
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0008 0.0002
Schistosoma mansoni hypothetical protein 0.0083 0.0188 0.0538
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0077 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0057 0.0159
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0057 0.0159
Loa Loa (eye worm) casein kinase II 0.0011 0.001 0.007
Entamoeba histolytica protein kinase, putative 0.006 0.0132 0.2012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0178 0.0425 0.1228
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0004
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0077 0.0071
Brugia malayi nuclear receptor NHR-67 0.0014 0.0018 0.0143
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0031 0.0338
Schistosoma mansoni hypothetical protein 0.0171 0.0407 0.1175
Leishmania major histone deacetylase, putative 0.0268 0.0646 0.8485
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0178 0.0425 0.1228
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.0008 0.0002
Schistosoma mansoni hypothetical protein 0.0083 0.019 0.0545
Plasmodium falciparum histone deacetylase 2 0.0314 0.076 0.0755
Plasmodium vivax DNA repair protein RAD2, putative 0.0011 0.001 0.0004
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Echinococcus granulosus histone deacetylase 8 0.0132 0.0311 0.0895
Loa Loa (eye worm) glutaminase 0.0276 0.0666 0.6026
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0089 0.1126
Brugia malayi Carboxylesterase family protein 0.0057 0.0125 0.1116
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0057 0.0135
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0006 0.0009
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0075 0.1125
Echinococcus multilocularis nibrin 0.0049 0.0104 0.025
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0261 0.063 0.5706
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0196 0.2938
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Echinococcus granulosus replication factor c subunit 1 0.0049 0.0104 0.0294
Trypanosoma brucei unspecified product 0.0064 0.0141 0.1822
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Loa Loa (eye worm) hypothetical protein 0.0086 0.0196 0.1754
Trichomonas vaginalis rotamase, putative 0.0032 0.0064 0.0958
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0033 0.0075
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0069 0.014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0018 0.0039
Echinococcus granulosus para nitrobenzyl esterase 0.0057 0.0125 0.0357
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0016 0.0032
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0071 0.0066
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0033 0.0496
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0104 0.1559
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0178 0.0425 0.3843
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0056 0.0133
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.092
Schistosoma mansoni histone deacetylase 1 2 3 0.0132 0.0311 0.0895
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Echinococcus multilocularis exonuclease 1 0.0011 0.001 0.0018
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0057 0.0135
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0031 0.0458
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Plasmodium falciparum protein kinase 5 0.0096 0.0222 0.0216
Loa Loa (eye worm) hypothetical protein 0.0122 0.0284 0.2562
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0018 0.0046
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0008 0.0015
Brugia malayi MH1 domain containing protein 0.0008 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Brugia malayi hypothetical protein 0.0009 0.0006 0.0027
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Trypanosoma brucei histone deacetylase 2 0.0132 0.0311 0.4058
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0035 0.0069 0.0064
Leishmania major DNA polymerase kappa, putative 0.0029 0.0055 0.0658
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0132 0.2012
Leishmania major DNA polymerase eta, putative 0.0118 0.0276 0.3588
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0077 0.0216
Echinococcus granulosus Immunoglobulin 0.0016 0.0022 0.0058
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Trypanosoma cruzi cdc2-related kinase 1 0.0096 0.0222 0.2876
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0003 0.0039
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0027 0.006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0047 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0069 0.0605
Onchocerca volvulus 0.0012 0.0014 0.0191
Brugia malayi DIX domain containing protein 0.0009 0.0006 0.0027
Brugia malayi Patched related family protein 4 0.0012 0.0014 0.01
Echinococcus multilocularis protein patched 0.0086 0.0196 0.0477
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0104 0.1325
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0178 0.0425 0.3843
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0016 0.0165
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0069 0.1038
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0037 0.0032
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0077 0.0952
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0057 0.0791
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0033 0.0088
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0018 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0057 0.0497
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0056 0.0697
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0055 0.0658
Schistosoma mansoni tar DNA-binding protein 0.007 0.0157 0.0448
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0035 0.0069 0.014
Loa Loa (eye worm) hypothetical protein 0.02 0.0477 0.4316
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trypanosoma cruzi cdc2-related kinase 1 0.0096 0.0222 0.2876
Toxoplasma gondii chorismate synthase, putative 0.4047 1 1
Loa Loa (eye worm) hypothetical protein 0.0339 0.0822 0.7451
Echinococcus multilocularis sterol regulatory element binding protein 0.0086 0.0196 0.0477
Echinococcus multilocularis cyclin dependent kinase 1 0.0096 0.0222 0.0542
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0047 0.0042
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0031 0.0024
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0268 0.0646 0.9705
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Brugia malayi hypothetical protein 0.0012 0.0014 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.0435 0.1257
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0006 0.0034
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0057 0.0051
Echinococcus granulosus tar DNA binding protein 0.007 0.0157 0.0448
Mycobacterium tuberculosis Probable reductase 0.0086 0.0197 0.0401
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0006 0.0009
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0016 0.001
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0077 0.0216
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0023 0.0183
Loa Loa (eye worm) hypothetical protein 0.0088 0.0201 0.1805
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0164 0.0389 0.0955
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0118 0.0275 0.0259
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Trichomonas vaginalis antibiotic synthetase, putative 0.0035 0.0069 0.1038
Entamoeba histolytica acyl-CoA synthetase, putative 0.0118 0.0275 0.4232
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0081 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0089 0.1109
Brugia malayi MH1 domain containing protein 0.0008 0.0004 0.0012
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0255 0.3828
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0016 0.0022 0.0058
Brugia malayi ecdysone receptor 0.0014 0.0018 0.0143
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0431 0.7462
Schistosoma mansoni ap endonuclease 0.0019 0.0031 0.0081
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0055 0.0675
Leishmania major 4-coumarate:coa ligase-like protein 0.0118 0.0275 0.3573
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0279 0.3625
Schistosoma mansoni rotamase 0.0032 0.0064 0.0178
Leishmania major 4-coumarate:coa ligase-like protein 0.0118 0.0275 0.3573
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0014 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0281 0.2534
Giardia lamblia Casein kinase II beta chain 0.0037 0.0075 0.1074
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0006 0.0009
Brugia malayi hypothetical protein 0.0049 0.0104 0.092
Toxoplasma gondii histone deacetylase HDAC4 0.0132 0.0311 0.0305
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Plasmodium vivax histone deacetylase, putative 0.0132 0.0311 0.0305
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0255 0.3828
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0057 0.0953
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.006 0.0166
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0368 0.0894 0.0879
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0104 0.1559
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0068
Schistosoma mansoni importin beta-1 0.0029 0.0056 0.0156
Schistosoma mansoni thyroid hormone receptor 0.003 0.0057 0.0159
Brugia malayi CXXC zinc finger family protein 0.0029 0.0056 0.0486
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0077 0.0157
Loa Loa (eye worm) hypothetical protein 0.0088 0.0201 0.1805
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0033 0.0027
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0009 0.0018
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0018 0.0143
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0646 0.9705
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Chlamydia trachomatis dehyroquinate synthase 0.0234 0.0564 0.0549
Echinococcus multilocularis muscleblind protein 1 0.0452 0.1103 0.2717
Loa Loa (eye worm) hypothetical protein 0.0026 0.0047 0.0405
Echinococcus granulosus cyclin dependent kinase 0.0096 0.0222 0.0638
Echinococcus multilocularis histone deacetylase 6 0.0314 0.076 0.1871
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0189 0.0384
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0023 0.0059
Brugia malayi topoisomerase 0.0049 0.0104 0.092
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0006 0.0094
Echinococcus granulosus snurportin 1 0.0314 0.076 0.22
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0004 0.0005
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0009 0.0006 0.0053
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0077 0.0675
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0057 0.0135
Echinococcus granulosus intestinal type alkaline phosphatase 0.0164 0.0389 0.1123
Echinococcus multilocularis microtubule associated protein 2 0.1399 0.3445 0.8503
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0018 0.0143
Schistosoma mansoni tar DNA-binding protein 0.007 0.0157 0.0448
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0057
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0069 0.014
Plasmodium falciparum DNA repair protein REV1, putative 0.0029 0.0055 0.0048
Trypanosoma cruzi histone deacetylase, putative 0.0314 0.076 1
Loa Loa (eye worm) hypothetical protein 0.025 0.0603 0.5457
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0006 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0055 0.0675
Plasmodium vivax histone deacetylase, putative 0.0314 0.076 0.0755
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0006 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0057 0.0497
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0016 0.001
Echinococcus granulosus dnaJ subfamily B 0.0417 0.1015 0.2941
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0011 0.001 0.0022
Loa Loa (eye worm) CMGC/GSK protein kinase 0.006 0.0132 0.1177
Loa Loa (eye worm) glutaminase 2 0.0276 0.0666 0.6026
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0234 0.0564 0.1019
Brugia malayi Carboxylesterase family protein 0.0057 0.0125 0.1116
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.009 0.1351
Echinococcus granulosus histone deacetylase 6 0.032 0.0775 0.2245
Echinococcus multilocularis para nitrobenzyl esterase 0.0057 0.0125 0.0303
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0254 0.0612 0.177
Schistosoma mansoni topbp1 0.0049 0.0104 0.0294
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0096 0.0222 0.2876
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0104 0.1559
Brugia malayi Patched related family protein 10 0.0012 0.0014 0.01
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0016 0.0039
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0006 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0158 0.2039
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0006 0.0007
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0012 0.0028
Brugia malayi hypothetical protein 0.0014 0.0018 0.0143
Brugia malayi histone deacetylase 11 0.0132 0.0311 0.28
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0049 0.0104 0.0071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0057 0.0497
Schistosoma mansoni histone deacetylase 4 5 0.0314 0.076 0.2201
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0047 0.0041
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0035 0.0069 0.014
Loa Loa (eye worm) histone deacetylase 7A 0.0314 0.076 0.6887
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0069 0.0849
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0096 0.0222 0.1996
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0049 0.0104 0.0098
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0055 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0222 0.0638
Plasmodium vivax histone deacetylase 1, putative 0.0268 0.0646 0.064
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.001 0.0151
Plasmodium vivax casein kinase II beta chain, putative 0.0037 0.0075 0.0069
Mycobacterium ulcerans DNA polymerase IV 0.0119 0.0279 0.0263
Entamoeba histolytica cell division protein kinase 2, putative 0.0096 0.0222 0.3414
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0004
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.019 0.0545
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0011 0.001 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0118 0.0275 0.0558
Loa Loa (eye worm) DR-78 0.0014 0.0018 0.0143
Schistosoma mansoni tar DNA-binding protein 0.007 0.0157 0.0448
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0035 0.0069 0.014
Brugia malayi conserved hypotetical protein 0.0014 0.0018 0.0143
Toxoplasma gondii patched family protein 0.0012 0.0014 0.0008
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0035 0.0069 0.014
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0035 0.0069 0.0053
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0031 0.0254
Brugia malayi cell division control protein 2 homolog 0.0096 0.0222 0.1996
Loa Loa (eye worm) hypothetical protein 0.0118 0.0276 0.2485
Echinococcus granulosus muscleblind protein 0.0452 0.1103 0.3196
Brugia malayi Protein kinase domain containing protein 0.0096 0.0222 0.1996
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0006 0.0009
Schistosoma mansoni hypothetical protein 0.0327 0.0794 0.2299
Plasmodium vivax glutathione reductase, putative 0.0038 0.0077 0.0071
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0006 0.0094
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0003 0.0039
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0049 0.0104 0.1308
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0092 0.0212 0.0518
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0089 0.1109
Trypanosoma cruzi histone deacetylase 1, putative 0.0268 0.0646 0.8485
Entamoeba histolytica recQ family helicase, putative 0.002 0.0033 0.0474
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0035 0.0069 0.0064
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Entamoeba histolytica hypothetical protein 0.0049 0.0104 0.1573
Plasmodium falciparum histone deacetylase, putative 0.0314 0.076 0.0755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus multilocularis acetylcholinesterase 0.0339 0.0822 0.2025
Onchocerca volvulus 0.0012 0.0014 0.0191
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Entamoeba histolytica protein kinase, putative 0.0182 0.0435 0.6725
Schistosoma mansoni nuclear receptor 0.0014 0.0018 0.0046
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.006 0.0054
Giardia lamblia Casein kinase II beta chain 0.0011 0.001 0.0063
Brugia malayi hypothetical protein 0.0122 0.0284 0.2562
Loa Loa (eye worm) histone methyltransferase 0.001 0.0009 0.0056
Onchocerca volvulus 0.0057 0.0125 0.214
Entamoeba histolytica acyl-coA synthetase, putative 0.0118 0.0275 0.4232
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0018 0.0046
Trypanosoma cruzi cdc2-related kinase 3 0.0096 0.0222 0.2876
Echinococcus multilocularis Niemann Pick C1 protein 0.02 0.0477 0.1173
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0006 0.0036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0055 0.0153
Leishmania major 4-coumarate:coa ligase-like protein 0.0118 0.0275 0.3573
Loa Loa (eye worm) DIX domain-containing protein 0.0009 0.0006 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0104 0.1308
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0009 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0047 0.0041
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0077 0.0957
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0311 0.4047
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Schistosoma mansoni smad 0.0008 0.0004 0.0004
Onchocerca volvulus 0.0014 0.0018 0.0275
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0018 0.0143
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0007 0.0044
Brugia malayi hypothetical protein 0.0014 0.0018 0.0143
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.009 0.1351
Echinococcus multilocularis histone deacetylase 6 0.032 0.0775 0.1909
Echinococcus multilocularis snurportin 1 0.0314 0.076 0.187
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0057 0.0844
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0006 0.0034
Plasmodium vivax DNA repair protein REV1, putative 0.0029 0.0055 0.0048
Echinococcus multilocularis GPCR, family 2 0.0079 0.018 0.0437
Schistosoma mansoni hypothetical protein 0.0083 0.0188 0.0538
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.0731 0.9616
Brugia malayi Muscleblind-like protein 0.0452 0.1103 1
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0008 0.0003 0.0039
Loa Loa (eye worm) hypothetical protein 0.0188 0.0448 0.4052
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Echinococcus multilocularis dna polymerase kappa 0.0119 0.0279 0.0682
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Brugia malayi 6-phosphofructokinase 0.011 0.0255 0.2294
Brugia malayi ImpB/MucB/SamB family protein 0.0118 0.0276 0.2485
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0006 0.0009
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0023 0.0235
Schistosoma mansoni jumonji domain containing protein 0.0059 0.013 0.0371
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.006 0.0132 0.032
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.009 0.0254
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0221 0.0313
Schistosoma mansoni exonuclease 0.0011 0.001 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0057 0.0497
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Loa Loa (eye worm) hypothetical protein 0.0088 0.0201 0.1805
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0031 0.0069
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0006 0.0034
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0031 0.0254
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0016 0.0022 0.0049
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0031 0.0379
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Plasmodium vivax chorismate synthase 0.4047 1 1
Mycobacterium ulcerans carboxylesterase, LipT 0.0057 0.0125 0.0109
Trichomonas vaginalis replication factor C large subunit, putative 0.0049 0.0104 0.1559
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0182 0.0435 0.5696
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.006 0.0141
Loa Loa (eye worm) patched family protein 0.0012 0.0014 0.01
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0069 0.0849
Loa Loa (eye worm) hypothetical protein 0.0152 0.0361 0.3254
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.006 0.0132 0.0376
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0183
Trypanosoma brucei DNA damage repair protein, putative 0.0029 0.0055 0.0675
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0047 0.0576
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.013 0.0371
Schistosoma mansoni apoptosis regulator bax 0.0083 0.019 0.0545
Brugia malayi jmjC domain containing protein 0.0016 0.0023 0.0183
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0602 0.1474 0.146
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0006 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0057 0.0854
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0037 0.0075 0.1125
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.092
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0157 0.1402
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0031 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0104 0.1559
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0026 0.0213
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0057 0.0051
Entamoeba histolytica Ran family GTPase 0.0022 0.0037 0.0537
Brugia malayi Carboxylesterase family protein 0.0057 0.0125 0.1116
Echinococcus multilocularis histone deacetylase 8 0.0132 0.0311 0.0761
Onchocerca volvulus Histone deacetylase 10 homolog 0.0132 0.0311 0.5372
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0055 0.0675
Mycobacterium tuberculosis Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase) 0.1996 0.4923 1
Onchocerca volvulus Protein patched homolog 0.0012 0.0014 0.0191
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0037 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0057 0.0497
Brugia malayi hypothetical protein 0.0016 0.0022 0.0181
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0118 0.1499
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Schistosoma mansoni chromosome transmission fidelity factor 0.0049 0.0104 0.0294
Entamoeba histolytica cell division protein kinase 2, putative 0.0096 0.0222 0.3414
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0182 0.0435 0.5696
Entamoeba histolytica exonuclease, putative 0.0011 0.001 0.0116
Brugia malayi Histone deacetylase family protein 0.0314 0.076 0.6887
Loa Loa (eye worm) hypothetical protein 0.0035 0.0069 0.0605
Schistosoma mansoni alkaline phosphatase 0.0164 0.0389 0.1123
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0197 0.0401
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0011 0.001 0.0022
Loa Loa (eye worm) patched family protein 0.0012 0.0014 0.01
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.003 0.0057 0.0116
Onchocerca volvulus 0.0118 0.0275 0.4747
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Brugia malayi AMP-binding enzyme family protein 0.0118 0.0275 0.2475
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0069 0.0866
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0006 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0018 0.0275
Schistosoma mansoni terminal deoxycytidyl transferase 0.0092 0.0212 0.061
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0602 0.1474 0.146
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0037 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0057 0.0497
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0011 0.001 0.0022
Echinococcus granulosus BC026374 protein S09 family 0.0057 0.0125 0.0357
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.0731 0.9616
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.001 0.0004
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.019 0.0545
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0255 0.0732
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0164 0.0389 0.0955
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0007 0.0044
Schistosoma mansoni dishevelled 0.0009 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0088 0.0201 0.1805
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.014 0.0399
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.006 0.0132 0.1683
Brugia malayi jmjC domain containing protein 0.0016 0.0023 0.0183
Brugia malayi AMP-binding enzyme family protein 0.0118 0.0275 0.2475
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0222 0.3339
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.018 0.0514
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0057 0.0135
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0646 0.9705
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0018 0.0046
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0062 0.0056
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.013 0.0315
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0018 0.0046
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0023 0.0017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0006 0.0034
Echinococcus multilocularis cyclin dependent kinase 0.0096 0.0222 0.0542
Loa Loa (eye worm) histone deacetylase 1 0.0268 0.0646 0.5847
Trichomonas vaginalis ran, putative 0.0022 0.0037 0.0558
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0275 0.0259
Brugia malayi polk-prov protein 0.0055 0.0121 0.1076
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0057 0.0497
Brugia malayi ecdysteroid receptor 0.003 0.0057 0.0497
Mycobacterium ulcerans chorismate synthase 0.4047 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0057 0.0125 0.0303
Brugia malayi hypothetical protein 0.0152 0.0361 0.3254
Trypanosoma brucei cdc2-related kinase 1 0.0096 0.0222 0.2889
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Echinococcus multilocularis protein dispatched 1 0.0098 0.0225 0.0551
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0033 0.039
Schistosoma mansoni neuroligin 3 (S09 family) 0.0057 0.0125 0.0357
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.001 0.012
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0077 0.0952
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Loa Loa (eye worm) hypothetical protein 0.0182 0.0433 0.3914
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.0212 0.1907
Schistosoma mansoni alkaline phosphatase 0.0164 0.0389 0.1123
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0576 0.8656
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Echinococcus multilocularis acetylcholinesterase 0.0339 0.0822 0.2025
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0033 0.0027
Loa Loa (eye worm) histone deacetylase 3 0.0268 0.0646 0.5847
Echinococcus granulosus neuroglian 0.0016 0.0022 0.0058
Loa Loa (eye worm) hypothetical protein 0.0132 0.0311 0.28
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0037 0.0075 0.1262
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0023 0.005
Mycobacterium ulcerans hypothetical protein 0.0029 0.0055 0.0039
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0057 0.0854
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0057 0.0159
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.0377 0.0767
Loa Loa (eye worm) hypothetical protein 0.0181 0.0431 0.389
Schistosoma mansoni histone deacetylase 0.0268 0.0646 0.1869
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0134 0.0383
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0016 0.0165
Brugia malayi intracellular kinase 0.006 0.0132 0.1177
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0057 0.0125 0.0357
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0018 0.0143
Echinococcus granulosus Smad4 0.0008 0.0004 0.0004
Onchocerca volvulus Protein patched homolog 0.0012 0.0014 0.0191
Loa Loa (eye worm) CMGC/GSK protein kinase 0.006 0.0132 0.1177
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0057 0.0159
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0008 0.0003 0.0039
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0069 0.0605
Brugia malayi nuclear hormone receptor 0.0014 0.0018 0.0143
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0118 0.0275 0.0259
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0057 0.0135
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0022 0.0181
Giardia lamblia hypothetical protein 0.0011 0.001 0.0059
Onchocerca volvulus 0.006 0.0132 0.2257
Echinococcus multilocularis dna polymerase eta 0.0118 0.0276 0.0675
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0255 0.0239
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0009 0.0051
Plasmodium falciparum thioredoxin reductase 0.0038 0.0077 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0077 0.1103
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0069 0.0605
Trypanosoma brucei DNA polymerase IV, putative 0.0113 0.0262 0.3419
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0043 0.0498
Schistosoma mansoni nephrin 0.0016 0.0022 0.0058
Plasmodium vivax SET domain protein, putative 0.0031 0.006 0.0053
Entamoeba histolytica hypothetical protein 0.004 0.0082 0.1234
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.0125 0.0254
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0057 0.0497
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0037 0.0075 0.0927
Echinococcus multilocularis bloom syndrome protein 0.002 0.0033 0.0075
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0255 0.0732
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0183
Echinococcus multilocularis protein kinase shaggy 0.006 0.0132 0.032
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0057 0.0953
Mycobacterium tuberculosis Conserved hypothetical protein 0.0092 0.0212 0.0431
Schistosoma mansoni microtubule-associated protein tau 0.1399 0.3445 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.0425 0.1044
Brugia malayi RNA, U transporter 1 0.0084 0.019 0.1707
Loa Loa (eye worm) histone deacetylase 11 0.0132 0.0311 0.28
Loa Loa (eye worm) hypothetical protein 0.0105 0.0243 0.2187
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0031 0.0356
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0083 0.0189 0.0384
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0314 0.076 0.6883
Echinococcus granulosus dual specificity 0.0182 0.0435 0.1257
Brugia malayi jmjC domain containing protein 0.0061 0.0134 0.1199
Loa Loa (eye worm) hypothetical protein 0.0118 0.0275 0.2475
Giardia lamblia Replication factor C, subunit 1 0.0049 0.0104 0.1524
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0037 0.0482
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.006 0.0132 0.0127
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0255 0.332
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0037 0.0444
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0057 0.0497
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0118 0.0275 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0158 0.2039
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0132 0.1984
Leishmania major trypanothione reductase 0.0038 0.0077 0.0957
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0099 0.0229 0.2965
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0011 0.001 0.0155
Loa Loa (eye worm) carboxylesterase 0.0339 0.0822 0.7451
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0057 0.0497
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0221 0.0449
Brugia malayi Myosin head containing protein 0.0012 0.0014 0.01
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0037 0.01
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0069 0.014
Schistosoma mansoni casein kinase II beta subunit 0.0037 0.0075 0.021
Brugia malayi XPG I-region family protein 0.0011 0.001 0.0068
Toxoplasma gondii ATPase, AAA family protein 0.0049 0.0104 0.0098
Loa Loa (eye worm) hypothetical protein 0.0098 0.0227 0.204
Loa Loa (eye worm) hypothetical protein 0.0118 0.0275 0.2475
Schistosoma mansoni hypothetical protein 0.0012 0.0012 0.0028
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0056 0.0051
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0023 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0057 0.0497
Mycobacterium ulcerans acetyl-CoA synthetase 0.0035 0.0069 0.0053
Echinococcus granulosus cpg binding protein 0.0031 0.006 0.0167
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0033 0.0277
Schistosoma mansoni cpg binding protein 0.0031 0.006 0.0167
Echinococcus multilocularis cyclin dependent kinase 5 0.0096 0.0222 0.0542
Echinococcus multilocularis expressed protein 0.0032 0.0064 0.0151
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0047 0.0559
Plasmodium vivax glycogen synthase kinase 3, putative 0.006 0.0132 0.0126
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0234 0.0564 0.1145
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0004
Leishmania major hypothetical protein, conserved 0.0011 0.001 0.0067
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0275 0.0259
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0057 0.0854
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0088 0.0201 0.0185
Echinococcus granulosus alkaline phosphatase 0.0164 0.0389 0.1123
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0035 0.0069 0.0053
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0062 0.0754
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0069 0.014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.013 0.0315
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0004 0.0004
Mycobacterium leprae Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase). 0.1996 0.4923 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.092
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0047 0.0559
Toxoplasma gondii ck2 beta subunit 0.0037 0.0075 0.0069
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0082 0.0231
Onchocerca volvulus 0.0035 0.0069 0.116
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0197 0.0401
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0049 0.0104 0.1559
Echinococcus multilocularis geminin 0.0327 0.0794 0.1955
Entamoeba histolytica hypothetical protein 0.0182 0.0435 0.6725
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.0064 0.0556
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0057 0.0159
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0009 0.0006 0.0001
Treponema pallidum DNA ligase (lig) 0.0049 0.0104 0.1073
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0035 0.0069 0.0849
Brugia malayi nuclear hormone receptor 0.003 0.0057 0.0497
Echinococcus granulosus Protein patched homolog 1 0.0086 0.0196 0.056
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0121 0.1551
Plasmodium vivax acyl-CoA synthetase, putative 0.0088 0.0201 0.0195
Trichomonas vaginalis flap endonuclease-1, putative 0.0011 0.001 0.0151
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0255 0.2292
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0203 0.0485 0.1402
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0016 0.0147
Leishmania major acetyl-CoA synthetase, putative 0.0035 0.0069 0.0849
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0255 0.392
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0057 0.0497
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0023 0.0059
Echinococcus granulosus bloom syndrome protein 0.002 0.0033 0.0088
Entamoeba histolytica DNA-repair protein, putative 0.0011 0.001 0.0116
Toxoplasma gondii thioredoxin reductase 0.0038 0.0077 0.0072
Plasmodium falciparum acyl-CoA synthetase 0.0088 0.0201 0.0195
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0023 0.005
Echinococcus granulosus histone deacetylase 3 0.0268 0.0646 0.1869
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0023 0.0016
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.019 0.0545
Echinococcus multilocularis Immunoglobulin 0.0016 0.0022 0.0049
Echinococcus multilocularis carboxylesterase 5A 0.0339 0.0822 0.2025
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Treponema pallidum NADH oxidase 0.0013 0.0016 0.0082
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0016 0.0153
Entamoeba histolytica histone deacetylase, putative 0.0268 0.0646 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0079 0.0188
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0009 0.0006 0.0027
Brugia malayi Flap endonuclease-1 0.0053 0.0114 0.101
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0254 0.0612 0.177
Echinococcus granulosus roundabout 2 0.0016 0.0022 0.0058
Plasmodium vivax acetyl-CoA synthetase, putative 0.0035 0.0069 0.0063
Brugia malayi glutaminase DH11.1 0.0276 0.0666 0.6026
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0054 0.0118 0.0113
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trypanosoma cruzi histone deacetylase, putative 0.0314 0.076 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0016 0.0165
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0035 0.0069 0.0866
Toxoplasma gondii hypothetical protein 0.0049 0.0104 0.0099
Plasmodium falciparum chorismate synthase 0.4047 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0057 0.0854
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Mycobacterium ulcerans acyl-CoA synthetase 0.0118 0.0275 0.0259
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0602 0.1474 0.1469
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0255 0.392
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0069 0.014
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0646 0.9705
Schistosoma mansoni zinc finger protein 0.0014 0.0018 0.0046
Brugia malayi Pre-SET motif family protein 0.021 0.0504 0.4561
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0345 0.0846
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0004 0.0012
Onchocerca volvulus 0.0049 0.0104 0.1765
Echinococcus multilocularis histone deacetylase 6 0.0314 0.076 0.1871
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0006 0.0011
Trypanosoma cruzi histone deacetylase 1, putative 0.0268 0.0646 0.8485
Trypanosoma cruzi DNA damage repair protein, putative 0.0029 0.0055 0.0658
Brugia malayi glutathione reductase 0.0038 0.0077 0.0679
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0077 0.1155
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Schistosoma mansoni acetyl-CoA synthetase 0.0035 0.0069 0.0193
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.006 0.0166
Brugia malayi jmjC domain containing protein 0.0016 0.0023 0.0183
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0057 0.0159
Brugia malayi protein C24B5.3 0.0012 0.0014 0.01
Schistosoma mansoni DNA ligase IV 0.0049 0.0104 0.0294
Brugia malayi CHE-14 protein 0.0086 0.0196 0.1754
Entamoeba histolytica deoxycytidyl transferase, putative 0.0092 0.0212 0.3262
Giardia lamblia Kinase, CMGC GSK 0.006 0.0132 0.1966
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0008 0.0003 0.0039
Echinococcus granulosus FTZ F1 alpha 0.003 0.0057 0.0159
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0221 0.0449
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0049 0.0104 0.1082
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0022 0.0049
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0023 0.0059
Brugia malayi Carboxylesterase family protein 0.0057 0.0125 0.1116
Plasmodium falciparum replication factor C subunit 1, putative 0.0049 0.0104 0.0098
Trypanosoma cruzi histone deacetylase, putative 0.0314 0.076 1
Plasmodium vivax importin-beta 2, putative 0.0029 0.0056 0.005
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0368 0.0894 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0033 0.0372
Loa Loa (eye worm) RNA binding protein 0.007 0.0157 0.1402
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0031 0.0434
Schistosoma mansoni nuclear receptor 0.0014 0.0018 0.0046
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0057 0.0051
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.0731 0.9616
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.0279 0.3637
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0062 0.0922
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0255 0.2292
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0104 0.1559
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.0407 0.3676
Schistosoma mansoni dishevelled 0.0009 0.0006 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0255 0.3828
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0035 0.0069 0.0053
Leishmania major histone deacetylase, putative 0.0268 0.0646 0.8485
Echinococcus granulosus importin subunit beta 1 0.0029 0.0056 0.0156
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0004 0.0004
Echinococcus granulosus cyclin dependent kinase 1 0.0096 0.0222 0.0638
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0057 0.0135
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0016 0.0091
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0016 0.0122
Loa Loa (eye worm) hypothetical protein 0.014 0.0331 0.2986
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0077 0.0216
Leishmania major GTP-binding protein, putative 0.0022 0.0037 0.0426
Trichomonas vaginalis rotamase, putative 0.0032 0.0062 0.093
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0057 0.0497
Echinococcus granulosus cyclin dependent kinase 5 0.0096 0.0222 0.0638
Echinococcus granulosus flap endonuclease GEN 1 0.0011 0.001 0.0022
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0011 0.001 0.012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.0337 0.4402
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0035 0.0069 0.0849
Trypanosoma cruzi cdc2-related kinase 3 0.0096 0.0222 0.2876
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.092
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0057 0.0051
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0006 0.0007
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0009 0.0006 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0057 0.0497
Loa Loa (eye worm) hypothetical protein 0.0254 0.0612 0.554
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0255 0.3828
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0006 0.0007
Brugia malayi Histone deacetylase family protein 0.0314 0.076 0.6887
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0104 0.1559
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0004 0.0005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0037 0.0426
Trichomonas vaginalis spcc417.12 protein, putative 0.0057 0.0125 0.1883
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0008 0.004
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0053 0.0114 0.144
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0057 0.0159
Onchocerca volvulus 0.0035 0.0069 0.116
Schistosoma mansoni coup transcription factor 0.003 0.0057 0.0159
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.0064 0.0556
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0345 0.0995
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0197 0.0401
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0164 0.0389 0.1123
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Echinococcus granulosus dna polymerase eta 0.0118 0.0276 0.0794
Echinococcus multilocularis neuroligin 0.0057 0.0125 0.0303
Mycobacterium ulcerans hypothetical protein 0.0118 0.0275 0.0259
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0016 0.0147
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0255 0.3307
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Loa Loa (eye worm) hypothetical protein 0.0079 0.018 0.1609
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0018 0.0039
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0602 0.1474 0.2894
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0504 0.4561
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0031 0.0338
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0118 0.0275 0.0424
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0077 0.0679
Brugia malayi Smad1 0.0008 0.0004 0.0012
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0057 0.0497
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0033 0.0496
Echinococcus multilocularis histone deacetylase 7 0.0314 0.076 0.1871
Brugia malayi Patched family protein 0.0012 0.0014 0.01
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0178 0.0425 0.1044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.018 0.0437
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0227 0.0652
Loa Loa (eye worm) hypothetical protein 0.0049 0.0104 0.092
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0118 0.0275 0.0558
Onchocerca volvulus 0.003 0.0057 0.0953
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0057 0.0159
Onchocerca volvulus 0.0012 0.0014 0.0191
Loa Loa (eye worm) patched family protein 0.0012 0.0014 0.01
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0016 0.0241
Echinococcus multilocularis histone deacetylase 0.0314 0.076 0.1871
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0057 0.0051
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.009 0.0084
Echinococcus granulosus histone deacetylase 7 0.0314 0.076 0.2201
Loa Loa (eye worm) hypothetical protein 0.0268 0.0646 0.5847
Schistosoma mansoni flap endonuclease-1 0.0048 0.0101 0.0287
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0057 0.0159
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.018 0.1609
Brugia malayi hypothetical protein 0.0017 0.0025 0.0201
Echinococcus granulosus Niemann Pick C1 protein 0.02 0.0477 0.1379
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0069 0.0605
Trichomonas vaginalis glutaminase, putative 0.0276 0.0666 1
Entamoeba histolytica exonuclease, putative 0.0011 0.001 0.0116
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.0368 0.0894 0.0879
Schistosoma mansoni hypothetical protein 0.0079 0.018 0.0514
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0018 0.0143
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0057 0.0041
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0164 0.0389 0.0955
Brugia malayi nuclear receptor RXR 0.0014 0.0018 0.0143
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0006 0.0027
Loa Loa (eye worm) Smad1 0.0008 0.0004 0.0012
Brugia malayi RNA binding protein 0.007 0.0157 0.1402
Loa Loa (eye worm) hypothetical protein 0.0094 0.0216 0.194
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0332 0.0804 0.7287
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0009 0.0006 0.0058
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0006 0.0034
Leishmania major histone deacetylase, putative 0.0314 0.076 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0086 0.0196 0.1754
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0077 0.1155
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0099 0.0229 0.0465
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0057 0.0125 0.0254
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0158 0.2039
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0016 0.0241
Toxoplasma gondii histone deacetylase HDAC1 0.0314 0.076 0.0755
Plasmodium falciparum exonuclease I, putative 0.0011 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0417 0.1015 0.2941
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0037 0.0314
Schistosoma mansoni tar DNA-binding protein 0.007 0.0157 0.0448
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0033 0.0418
Brugia malayi hypothetical protein 0.0026 0.0047 0.0405
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0035 0.0069 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.006 0.0166
Schistosoma mansoni hypothetical protein 0.0083 0.0188 0.0538
Entamoeba histolytica hypothetical protein 0.004 0.0082 0.1234
Loa Loa (eye worm) hypothetical protein 0.0031 0.006 0.0519
Plasmodium falciparum glutathione reductase 0.0038 0.0077 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0035 0.0069 0.0053
Onchocerca volvulus 0.0239 0.0576 1
Schistosoma mansoni histone deacetylase hda2 0.032 0.0775 0.2245
Loa Loa (eye worm) patched family protein 0.0012 0.0014 0.01
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Echinococcus granulosus expressed conserved protein 0.0187 0.0448 0.1292
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0016 0.001
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0057 0.0159
Trypanosoma brucei cdc2-related kinase 3 0.0096 0.0222 0.2889
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0231
Schistosoma mansoni tar DNA-binding protein 0.007 0.0157 0.0448
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Onchocerca volvulus 0.0009 0.0006 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Giardia lamblia Kinase, CMGC CDK 0.0096 0.0222 0.3376
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0018 0.0039
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0008 0.0058
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0234 0.0564 0.1145
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0004 0.0004
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0089 0.1109
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0008 0.0003 0.0039
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0011 0.001 0.0004
Giardia lamblia Kinase, CMGC CDK 0.0096 0.0222 0.3376
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0018 0.0275
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0035 0.0069 0.0164
Brugia malayi Niemann-Pick C1 protein precursor 0.02 0.0477 0.4316
Trypanosoma brucei unspecified product 0.0113 0.0262 0.3419
Schistosoma mansoni hypothetical protein 0.0083 0.019 0.0545
Brugia malayi hypothetical protein 0.0012 0.0014 0.01
Trypanosoma brucei unspecified product 0.0064 0.0141 0.1822
Trypanosoma brucei chrX additional, unordered contigs 0.0029 0.0055 0.0675
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0057 0.0497
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0082 0.0231
Onchocerca volvulus 0.0057 0.0125 0.214
Echinococcus granulosus histone deacetylase 6 0.0314 0.076 0.2201
Brugia malayi nuclear receptor NHR-88 0.0014 0.0018 0.0143
Schistosoma mansoni BC026374 protein (S09 family) 0.0057 0.0125 0.0357
Trypanosoma cruzi hypothetical protein, conserved 0.0049 0.0104 0.1308
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0035 0.0069 0.014
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0057 0.0135
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0057 0.0854
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0011 0.001 0.0018
Leishmania major DNA polymerase eta, putative 0.0054 0.0118 0.1499
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0004 0.0003
Echinococcus multilocularis histone deacetylase 3 0.0268 0.0646 0.1589
Echinococcus granulosus geminin 0.0327 0.0794 0.2299
Plasmodium falciparum thioredoxin reductase 0.0013 0.0016 0.001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0022 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0016 0.0147
Entamoeba histolytica Flap nuclease, putative 0.0053 0.0114 0.1728
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Schistosoma mansoni DNA helicase recq1 0.002 0.0033 0.0088
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0006 0.0018
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0016 0.0147
Loa Loa (eye worm) hypothetical protein 0.0057 0.0125 0.1116
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0057 0.0135
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0008 0.0003 0.0039
Entamoeba histolytica recQ family helicase, putative 0.001 0.0008 0.0082
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0023 0.0059
Schistosoma mansoni DNA polymerase IV / kappa 0.0029 0.0055 0.0151
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0012 0.0024
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0031 0.0338
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.006 0.0141
Entamoeba histolytica hypothetical protein 0.0024 0.0043 0.0622
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0222 0.3339
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.009 0.0084
Giardia lamblia DINP protein human, muc B family 0.0099 0.0229 0.348
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Loa Loa (eye worm) hypothetical protein 0.0009 0.0006 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0022 0.0181
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0057 0.0135
Brugia malayi hypothetical protein 0.0016 0.0022 0.0181
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.1015 0.2501
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0197 0.0401
Loa Loa (eye worm) hypothetical protein 0.018 0.0429 0.3876
Brugia malayi hypothetical protein 0.0012 0.0014 0.01
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0279 0.3625
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.0731 0.9617
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0222 0.3339
Schistosoma mansoni ran 0.0022 0.0037 0.01
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0033 0.0496
Trypanosoma cruzi DNA polymerase kappa, putative 0.0119 0.0279 0.3625
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Schistosoma mansoni hypothetical protein 0.0085 0.0194 0.0557
Trypanosoma brucei trypanothione reductase 0.0038 0.0077 0.0974
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0077 0.1155
Loa Loa (eye worm) phosphofructokinase 0.011 0.0255 0.2292
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0088 0.0201 0.0185
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0031 0.0014
Trypanosoma brucei histone deacetylase 3 0.0314 0.076 1
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0016 0.0147
Loa Loa (eye worm) hypothetical protein 0.0452 0.1103 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0023 0.0017
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0096 0.0222 0.0638
Onchocerca volvulus 0.0057 0.0125 0.214
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0157 0.1402
Onchocerca volvulus 0.0035 0.0069 0.116
Loa Loa (eye worm) hypothetical protein 0.0029 0.0056 0.0488
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0009 0.0006 0.0094
Trypanosoma cruzi histone deacetylase, putative 0.0132 0.0311 0.4047
Echinococcus multilocularis smad 0.0008 0.0004 0.0003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0033 0.0027
Plasmodium falciparum glutathione reductase 0.0013 0.0016 0.001
Echinococcus granulosus sterol regulatory element binding protein 0.0086 0.0196 0.056
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Schistosoma mansoni cpg binding protein 0.0031 0.006 0.0167
Loa Loa (eye worm) hypothetical protein 0.0016 0.0022 0.0181
Echinococcus granulosus acetylcholinesterase 0.0339 0.0822 0.2381
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.001 0.0067
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0646 0.9705
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Plasmodium vivax patched family protein, putative 0.0012 0.0014 0.0007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0014 0.01
Trichomonas vaginalis casein kinase II beta chain, putative 0.0037 0.0075 0.1126
Trypanosoma brucei DNA polymerase kappa, putative 0.0119 0.0279 0.3637
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0011 0.001 0.0155
Plasmodium falciparum casein kinase II beta chain 0.0037 0.0075 0.0069
Plasmodium falciparum flap endonuclease 1 0.0053 0.0114 0.0108
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0006 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0018 0.0046
Entamoeba histolytica hypothetical protein 0.004 0.0082 0.1234
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0031 0.0458
Echinococcus multilocularis flap endonuclease 1 0.0053 0.0114 0.0275
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0081 0.1169
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0143
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0255 0.2779
Trichomonas vaginalis casein kinase II beta chain, putative 0.0011 0.001 0.0155
Loa Loa (eye worm) Csnk2b protein 0.0037 0.0075 0.0658
Trichomonas vaginalis histone deacetylase, putative 0.0268 0.0646 0.9705

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.01 uM Binding affinity for human glycogen synthase kinase 3 beta ChEMBL. 15341487
Ki (binding) = 0.01 uM Binding affinity for human glycogen synthase kinase 3 beta ChEMBL. 15341487
Ki (binding) > 19.95 uM Binding affinity for human cyclin-dependent kinase 2 ChEMBL. 15341487
Ki (binding) > 19.95 uM Binding affinity for human cyclin-dependent kinase 2 ChEMBL. 15341487

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.