Detailed information for compound 320217

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 226.105 | Formula: C13H17BN3+
  • H donors: 0 H acceptors: 1 LogP: 1.78 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CB[n+]1ccc2c(c1)[C@@H]1[C@H](CC2)CCN1C
  • InChi: 1S/C13H17BN3/c1-16-6-4-11-3-2-10-5-7-17(14-9-15)8-12(10)13(11)16/h5,7-8,11,13-14H,2-4,6H2,1H3/q+1/t11-,13+/m0/s1
  • InChiKey: MWWRDAZOCUTDIJ-WCQYABFASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni sulfide quinone reductase 0.0116 0.0718 0.0718
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0033 0.0033
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0077 0.0451 0.107
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0261
Echinococcus granulosus dro:myosuppressin receptor 0.0077 0.0451 0.0451
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0116 0.0718 0.3027
Schistosoma mansoni lamin 0.0057 0.0308 0.0308
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0073 0.0073
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0083 0.0185
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.038 0.0384
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0032 0.0134 0.0134
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0019 0.0046 0.0089
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0434 0.0434
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0019 0.0046 0.0111
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0734 0.074
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0238 0.1568 0.3766
Schistosoma mansoni neuropeptide receptor 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Loa Loa (eye worm) inositol-1 0.0033 0.0144 0.0326
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Plasmodium vivax ferredoxin, putative 0.0023 0.0071 0.0172
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0261
Leishmania major cytochrome p450-like protein 0.0033 0.0146 0.0147
Brugia malayi Cytochrome P450 family protein 0.0052 0.0274 0.0647
Brugia malayi Pre-SET motif family protein 0.0438 0.296 0.7146
Schistosoma mansoni tyrosine kinase 0.0041 0.0198 0.0198
Echinococcus multilocularis inositol monophosphatase 1 0.0033 0.0144 0.0144
Trypanosoma brucei cytochrome P450, putative 0.0052 0.0274 0.0276
Trichomonas vaginalis Ferredoxin 2 0.0023 0.0071 0.0128
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0077 0.0451 0.1077
Brugia malayi N-terminal motif family protein 0.0206 0.1347 0.3244
Loa Loa (eye worm) hypothetical protein 0.0019 0.0048 0.0092
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0116 0.0718 0.2402
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Brugia malayi Thioredoxin reductase 0.0608 0.414 1
Brugia malayi cytochrome P450 0.0033 0.0146 0.0337
Echinococcus multilocularis fmrfamide receptor 0.0077 0.0451 0.0451
Onchocerca volvulus 0.0138 0.0874 0.2554
Toxoplasma gondii FATC domain-containing protein 0.0018 0.0038 0.0092
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0014 0.0014
Onchocerca volvulus 0.0138 0.0874 0.2554
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Loa Loa (eye worm) hypothetical protein 0.0398 0.2683 0.6474
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0061 0.0126
Onchocerca volvulus 0.0041 0.0202 0.0557
Brugia malayi hypothetical protein 0.0034 0.0152 0.0352
Trypanosoma brucei protein kinase, putative 0.0107 0.0658 0.0664
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Echinococcus multilocularis survival motor neuron protein 1 0.0497 0.337 0.337
Echinococcus granulosus neuropeptide FF receptor 2 0.0077 0.0451 0.0451
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0144 0.0145
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.054
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0332 0.2224 0.5356
Schistosoma mansoni importin beta-1 0.0026 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0527 0.3576 0.8635
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0282 0.0681
Brugia malayi Inositol-1 0.0033 0.0144 0.0333
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Loa Loa (eye worm) melatonin receptor type 1A 0.0077 0.0451 0.107
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0042 0.0042
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0116 0.0718 0.1715
Loa Loa (eye worm) blistered cuticle protein 3 0.0074 0.0427 0.1012
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0039 0.0183 0.0421
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0238 0.1568 0.4963
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0073 0.0153
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.028 0.028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0077 0.0451 0.0451
Echinococcus multilocularis nAChR subunit 0.0053 0.028 0.028
Echinococcus multilocularis neuropeptides capa receptor 0.0077 0.0451 0.0451
Chlamydia trachomatis thioredoxin reductase 0.0116 0.0718 0.2402
Loa Loa (eye worm) hypothetical protein 0.0104 0.0637 0.1519
Mycobacterium tuberculosis Probable reductase 0.0116 0.0718 0.1705
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0107 0.0658 0.0664
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0023 0.0073 0.0073
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0059 0.0059
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0014 0.0014 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1739 0.3601
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0261
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0071 0.0072
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0059 0.0188
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Brugia malayi ERG2 and Sigma1 receptor like protein 0.04 0.2692 0.6499
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0175 0.0409
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0116 0.0718 0.1474
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0061 0.0134
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.028 0.0655
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0199 0.0199
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0061 0.0134
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0116 0.0718 0.0718
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0135 0.0413
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.107 0.7354 0.7418
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0077 0.0451 0.0451
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0033 0.0146 0.0318
Treponema pallidum oxidoreductase 0.0116 0.0718 0.2402
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0056 0.0112
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0017 0.003 0.003
Brugia malayi ORL1-like opioid receptor 0.0077 0.0451 0.1077
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.028 0.028
Echinococcus granulosus cGMP dependent protein kinase 0.0015 0.0021 0.0021
Schistosoma mansoni nAChR subunit 0.0024 0.0083 0.0083
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0019 0.0046 0.0111
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0033 0.0144 0.0306
Loa Loa (eye worm) thioredoxin reductase 0.0608 0.414 1
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0116 0.0718 0.2272
Echinococcus multilocularis orexin receptor type 2 0.0077 0.0451 0.0451
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0056 0.0102
Schistosoma mansoni myosin xvIII 0.0077 0.0451 0.0451
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0014 0.0014 0.0014
Schistosoma mansoni zinc finger protein 0.0017 0.0029 0.0029
Trichomonas vaginalis aldehyde oxidase, putative 0.0705 0.4814 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0101 0.0619 0.1482
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0734 0.1508
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0116 0.0718 0.2293
Onchocerca volvulus 0.0262 0.1738 0.5121
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0116 0.0718 0.1734
Mycobacterium ulcerans hypothetical protein 0.002 0.0056 0.0178
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0135 0.0413
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0111 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0015 0.0022
Schistosoma mansoni sodium/chloride dependent transporter 0.0262 0.1738 0.1738
Echinococcus granulosus patatin phospholipase domain containing protein 0.0014 0.0014 0.0014
Onchocerca volvulus 0.0077 0.0451 0.1298
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.0138 0.0138
Echinococcus granulosus allatostatin A receptor 0.0077 0.0451 0.0451
Trichomonas vaginalis ran, putative 0.0019 0.0046 0.0075
Mycobacterium ulcerans electron transfer protein FdxB 0.0023 0.0071 0.0225
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0111 0.0246
Echinococcus multilocularis musashi 0.0057 0.0308 0.0308
Echinococcus granulosus cpg binding protein 0.0033 0.0143 0.0143
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0014 0.0014 0.0014
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0184 0.0184
Brugia malayi hypothetical protein 0.0024 0.0083 0.0185
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0014 0.0014 0.0012
Schistosoma mansoni cytochrome P450 0.0033 0.0146 0.0146
Mycobacterium ulcerans regulatory protein 0.0014 0.0014 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0175 0.0344
Entamoeba histolytica hypothetical protein 0.0032 0.0138 0.0582
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0041 0.0199 0.0459
Toxoplasma gondii hypothetical protein 0.0045 0.0223 0.054
Onchocerca volvulus 0.0077 0.0451 0.1298
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Loa Loa (eye worm) apoptosis regulator protein 0.009 0.0539 0.1281
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0019 0.0046 0.0111
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Schistosoma mansoni rab6-interacting 0.0041 0.0202 0.0202
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0015 0.0015
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.009 0.0539 0.0539
Echinococcus granulosus biogenic amine 5HT receptor 0.046 0.3112 0.3112
Echinococcus granulosus sex peptide receptor 0.0077 0.0451 0.0451
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Schistosoma mansoni ran 0.0019 0.0046 0.0046
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0053 0.028 0.0662
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0014 0.0009
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0077 0.0451 0.0451
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0038 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0093 0.0094
Mycobacterium ulcerans glutamate synthase subunit beta 0.0116 0.0718 0.2272
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0292 0.0925
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0637 0.0637
Entamoeba histolytica protein kinase rad3, putative 0.0018 0.0038 0.016
Echinococcus granulosus neuropeptide Y receptor 0.0077 0.0451 0.0451
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0077 0.0451 0.107
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0107 0.0658 0.0664
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0061 0.0061
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0061 0.0134
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0014 0.0014 0.0034
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0033 0.0033
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0116 0.0718 0.0724
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0077 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0014 0.0014 0.0014
Onchocerca volvulus 0.0024 0.0083 0.0203
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0292 0.0925
Mycobacterium ulcerans hypothetical protein 0.0115 0.071 0.2248
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0014 0.0014 0.0014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0436 0.2943 0.71
Mycobacterium ulcerans monoxygenase 0.0116 0.0718 0.2272
Echinococcus multilocularis serotonin transporter 0.0262 0.1738 0.1738
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.028 0.0662
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0033 0.0033
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0262 0.1738 0.1738
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0056 0.0141
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0023 0.0073 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0306 0.0617
Leishmania major hypothetical protein, conserved 0.0116 0.0718 0.0724
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0033 0.0146 0.0461
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.017 0.017
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0718 0.1705
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0198 0.0198
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0199 0.0199
Leishmania major C-8 sterol isomerase-like protein 0.04 0.2692 0.2716
Brugia malayi MAP kinase sur-1 0.0107 0.0658 0.1578
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0223 0.0223
Echinococcus multilocularis g-protein coupled receptor 0.0077 0.0451 0.0451
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0718 0.2402
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0035 0.0155 0.0156
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0144 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0061 0.0134
Toxoplasma gondii exonuclease III APE 0.002 0.0056 0.0134
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0223 0.054
Giardia lamblia Kinase, CMGC MAPK 0.0107 0.0658 0.2199
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0436 0.2943 0.2969
Plasmodium falciparum importin beta, putative 0.0026 0.0093 0.0226
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Echinococcus granulosus snurportin 1 0.0276 0.1832 0.1832
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Brugia malayi nuclear receptor NHR-88 0.0021 0.0061 0.0134
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0456 0.11
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0023 0.0071 0.0169
Plasmodium vivax ferrodoxin reductase, putative 0.0116 0.0718 0.1734
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Toxoplasma gondii thioredoxin reductase 0.0608 0.414 1
Echinococcus granulosus dna polymerase eta 0.0021 0.0059 0.0059
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0116 0.0718 0.0724
Echinococcus multilocularis geminin 0.0356 0.239 0.239
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0057 0.0308 0.0723
Leishmania major trypanothione reductase 0.0608 0.414 0.4176
Schistosoma mansoni sodium-dependent amino acid transporter 0.0045 0.0223 0.0223
Schistosoma mansoni cpg binding protein 0.0029 0.0117 0.0117
Onchocerca volvulus 0.0116 0.0718 0.2089
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0198 0.0198
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0077 0.0451 0.107
Entamoeba histolytica hypothetical protein 0.0028 0.0111 0.0468
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0276 0.1832 0.1832
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0116 0.0718 0.1734
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0038 0.0077
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0111 0.0254
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0033 0.0064
Echinococcus granulosus metabotropic glutamate receptor 2 0.0045 0.0226 0.0226
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0059 0.006
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0038 0.0175 0.0401
Schistosoma mansoni adrenodoxin 0.0023 0.0071 0.0071
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0033 0.0033
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0116 0.0718 0.1722
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0095 0.0095
Brugia malayi Receptor family ligand binding region containing protein 0.0014 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0186 0.0428
Brugia malayi intermediate filament protein 0.0057 0.0308 0.073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0135 0.0849 0.2688
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0061 0.0061
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0014 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Loa Loa (eye worm) hypothetical protein 0.009 0.0539 0.1281
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.029 0.0686
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0116 0.0718 0.1705
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.054
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0135 0.0327
Schistosoma mansoni cpg binding protein 0.0033 0.0143 0.0143
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.038 0.1604
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0094 0.0571 0.0576
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0116 0.0718 0.1705
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0035 0.0155 0.0156
Echinococcus granulosus intermediate filament protein 0.0057 0.0308 0.0308
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0202 0.0488
Trypanosoma cruzi Flagellar Member 6 0.0014 0.0014 0.0014
Trichomonas vaginalis glutamate synthase, putative 0.0116 0.0718 0.1474
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0094 0.0571 0.0576
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0175 0.0177
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.028 0.0655
Schistosoma mansoni growth hormone secretagogue receptor 0.0077 0.0451 0.0451
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0077 0.0451 0.1077
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0727 0.4968 0.4968
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0056 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0021 0.0021
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0033 0.0146 0.0318
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0282 0.0285
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0033 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0059 0.006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0033 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0094 0.0571 0.0576
Echinococcus granulosus tumor protein p63 0.071 0.4852 0.4852
Onchocerca volvulus 0.0077 0.0451 0.1298
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0077 0.0451 0.107
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0014 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0071 0.0404 0.0957
Leishmania major cytochrome p450-like protein 0.0033 0.0146 0.0147
Brugia malayi Pre-SET motif family protein 0.0063 0.0354 0.0843
Echinococcus granulosus neuropeptides capa receptor 0.0077 0.0451 0.0451
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0042 0.0042
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0276 0.1832 0.4414
Onchocerca volvulus 0.0021 0.0061 0.014
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.028 0.0662
Schistosoma mansoni glutamate synthase 0.0116 0.0718 0.0718
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0083 0.0185
Brugia malayi steroid hormone receptor 0.0021 0.0061 0.0134
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0116 0.0718 0.2402
Schistosoma mansoni hypothetical protein 0.0077 0.0451 0.0451
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0073 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0354 0.0354
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0061 0.0134
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0078 0.0456 0.108
Mycobacterium tuberculosis Probable oxidoreductase 0.0436 0.2943 0.71
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0436 0.0888
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0077 0.0451 0.1077
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0059 0.0059
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0045 0.0223 0.0223
Schistosoma mansoni neuropeptide F-like receptor 0.0077 0.0451 0.0451
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0116 0.0718 0.1474
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0033 0.0146 0.0461
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0061 0.0061
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0014 0.0014 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0718 0.0724
Giardia lamblia DINP protein human, muc B family 0.0021 0.0059 0.0154
Echinococcus granulosus GTP binding nuclear protein Ran 0.0019 0.0046 0.0046
Mycobacterium leprae Conserved hypothetical protein 0.0033 0.0146 0.0448
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0061 0.0338 0.0338
Trypanosoma cruzi target of rapamycin kinase 3 0.0075 0.0437 0.044
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0033 0.0146 0.0318
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1218 0.838 0.8453
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0438 0.296 0.7144
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0046 0.0046
Schistosoma mansoni apoptosis regulator bax 0.009 0.0539 0.0539
Brugia malayi Cytochrome P450 family protein 0.0033 0.0146 0.0337
Onchocerca volvulus 0.011 0.0678 0.1971
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0023 0.0071 0.015
Onchocerca volvulus 0.0077 0.0451 0.1298
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0073 0.0073
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0056 0.0121
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0061 0.014
Schistosoma mansoni adenoreceptor 0.0077 0.0451 0.0451
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.028 0.028
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0274 0.0276
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0014 0.0034
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Onchocerca volvulus Dual oxidase homolog 0.0074 0.0427 0.1227
Echinococcus granulosus Ankyrin 0.0015 0.0016 0.0016
Echinococcus granulosus survival motor neuron protein 1 0.0497 0.337 0.337
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0066 0.0373 0.0373
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0658 0.0664
Mycobacterium ulcerans oxidoreductase 0.0023 0.0071 0.0225
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.028 0.0662
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0077 0.0451 0.1298
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0262 0.1738 0.4186
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Loa Loa (eye worm) hypothetical protein 0.0015 0.0016 0.0017
Schistosoma mansoni amine GPCR 0.0077 0.0451 0.0451
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0061 0.0061
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0019 0.0046 0.0046
Echinococcus granulosus death domain containing protein 0.0015 0.0015 0.0015
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0447 0.091
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0209 0.1366 0.4324
Brugia malayi Serotonin receptor 0.0077 0.0451 0.1077
Echinococcus multilocularis tumor protein p63 0.071 0.4852 0.4852
Echinococcus granulosus 7tm_1 domain containing protein 0.0077 0.0451 0.0451
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0098 0.0592 0.0592
Brugia malayi GnHR receptor homolog 0.0077 0.0451 0.1077
Schistosoma mansoni neuropeptide F-like receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0198 0.0198
Mycobacterium ulcerans NADH dehydrogenase 0.0116 0.0718 0.2272
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.002 0.0056 0.0113
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0122 0.0122
Brugia malayi isocitrate dehydrogenase 0.0017 0.0033 0.0065
Plasmodium vivax thioredoxin reductase, putative 0.0608 0.414 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0032 0.0134 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0658 0.135
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0023 0.0073 0.0153
Onchocerca volvulus 0.0057 0.0308 0.0872
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0116 0.0718 0.0724
Schistosoma mansoni opsin-like receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis Ankyrin 0.0015 0.0016 0.0016
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0398 0.2683 0.6476
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0116 0.0718 0.2272
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0061 0.0134
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0066 0.0373 0.0881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0538
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0117 0.026
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.1176 0.2428
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.038 0.0384
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Loa Loa (eye worm) hypothetical protein 0.021 0.137 0.3295
Brugia malayi Dopamine receptor protein 1 0.0077 0.0451 0.1077
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0014 0.0014 0.0014
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.028 0.028
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0116 0.0718 0.0724
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Schistosoma mansoni disulfide oxidoreductase 0.0116 0.0718 0.0718
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Brugia malayi G protein-coupled receptor F59B2.13 0.0077 0.0451 0.1077
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0075 0.0437 0.044
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0032 0.0134 0.0135
Trypanosoma cruzi trypanothione reductase, putative 0.0608 0.414 0.4176
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0098 0.0592 0.0592
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0083 0.0083
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0039 0.0183 0.0773
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0033 0.0146 0.0461
Echinococcus multilocularis allatostatin A receptor 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.002 0.0052 0.0104
Schistosoma mansoni biogenic amine receptor 0.0077 0.0451 0.0451
Schistosoma mansoni adrenodoxin 0.0023 0.0071 0.0071
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Leishmania major hypothetical protein, conserved 0.0014 0.0014 0.0014
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0056 0.0095
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0033 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0046 0.0075
Echinococcus granulosus ferredoxin 0.0023 0.0071 0.0071
Echinococcus multilocularis neuropeptide receptor 0.0077 0.0451 0.0451
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0083 0.0185
Loa Loa (eye worm) hypothetical protein 0.0206 0.1347 0.3239
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0376 0.0376
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0198 0.0198
Treponema pallidum hypothetical protein 0.0094 0.057 0.1896
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0014 0.0014
Brugia malayi follicle stimulating hormone receptor 0.0561 0.3813 0.9211
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0175 0.0344
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0248 0.1638 0.1638
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0077 0.0451 0.0451
Schistosoma mansoni biogenic amine receptor 0.0077 0.0451 0.0451
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.009 0.0539 0.0539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0538
Loa Loa (eye worm) hypothetical protein 0.0398 0.2683 0.6474
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Onchocerca volvulus 0.0023 0.0071 0.0169
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0053 0.028 0.0655
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0082 0.0483 0.0483
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0056 0.0056
Echinococcus multilocularis conserved hypothetical protein 0.0749 0.5121 0.5121
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0734 0.0734
Brugia malayi hypothetical protein 0.0024 0.0083 0.0185
Mycobacterium ulcerans endonuclease IV 0.0078 0.0456 0.1442
Brugia malayi Egg laying defective protein 4 0.0015 0.0021 0.0036
Treponema pallidum sodium- and chloride- dependent transporter 0.0262 0.1738 0.5887
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0014 0.0034
Loa Loa (eye worm) SRC-1 0.0041 0.0198 0.0456
Echinococcus granulosus metabotropic glutamate receptor 5 0.0066 0.0373 0.0373
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0223 0.0223
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0017 0.0033 0.0033
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0116 0.0718 0.1722
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0059 0.0059
Brugia malayi Blistered cuticle protein 3 0.0074 0.0427 0.1019
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0142 0.0142
Loa Loa (eye worm) TK protein kinase 0.0037 0.017 0.0389
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0014 0.0014 0.0014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0021 0.0024
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0116 0.0718 0.0724
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0033 0.0033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0026 0.0026
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0042 0.0042
Echinococcus granulosus importin subunit beta 1 0.0026 0.0093 0.0093
Trypanosoma brucei Flagellar Member 6 0.0014 0.0014 0.0014
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0094 0.0571 0.2406
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0116 0.0718 0.0724
Echinococcus multilocularis G protein coupled receptor 139 0.0077 0.0451 0.0451
Brugia malayi nuclear hormone receptor 0.0021 0.0061 0.0134
Brugia malayi M-phase phosphoprotein, mpp8 0.011 0.0678 0.1625
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.034 0.0688
Trichomonas vaginalis glutamate synthase, putative 0.0116 0.0718 0.1474
Mycobacterium ulcerans ferredoxin reductase 0.0116 0.0718 0.2272
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0202 0.0488
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.029 0.0686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.009 0.0167
Echinococcus granulosus somatostatin receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.028 0.028
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0317 0.2119 0.8937
Schistosoma mansoni neuropeptide f receptor 76f 0.0077 0.0451 0.0451
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.017 0.017
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0059 0.0121
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0033 0.0146 0.0318
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0116 0.0718 0.1705
Echinococcus multilocularis thioredoxin glutathione reductase 0.0608 0.414 0.414
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0134 0.0259
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0292 0.0925
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0033 0.0146 0.0318
Brugia malayi G protein-coupled receptor 0.0077 0.0451 0.1077
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0162 0.0162
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0308 0.073
Echinococcus multilocularis neuropeptide Y receptor 0.0077 0.0451 0.0451
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.028 0.028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0447 0.091
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0734 0.3095
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Echinococcus granulosus fmrfamide receptor 0.0077 0.0451 0.0451
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0033 0.0033
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0014 0.0014
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0116 0.0718 0.0718
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0436 0.2943 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0014 0.0014 0.0009
Schistosoma mansoni opsin-like receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0175 0.0175
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.0518
Schistosoma mansoni fkbp-rapamycin associated protein 0.0018 0.0038 0.0038
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0116 0.0718 0.3027
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.028 0.0662
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.0734 0.074
Leishmania major hypothetical protein, unknown function 0.0014 0.0014 0.0014
Brugia malayi hypothetical protein 0.0032 0.0138 0.0319
Onchocerca volvulus Neuropeptide F receptor homolog 0.0077 0.0451 0.1298
Giardia lamblia Fructose-bisphosphate aldolase 0.0317 0.2119 0.7187
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0202 0.0202
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0077 0.0451 0.0451
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0033 0.0033
Schistosoma mansoni voltage-gated potassium channel 0.0092 0.0555 0.0555
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0116 0.0718 0.3027
Brugia malayi hypothetical protein 0.0024 0.0083 0.0185
Schistosoma mansoni polycystin 1-related 0.0041 0.0202 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0061 0.0126
Trypanosoma cruzi trypanothione reductase, putative 0.0436 0.2943 0.2969
Plasmodium falciparum ferredoxin, putative 0.0023 0.0071 0.0172
Loa Loa (eye worm) hypothetical protein 0.011 0.0678 0.1619
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.038 0.038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0041 0.0202 0.0466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0038 0.0059
Echinococcus granulosus tm gpcr rhodopsin 0.0077 0.0451 0.0451
Onchocerca volvulus 0.0057 0.0308 0.0872
Schistosoma mansoni zinc finger protein 0.0023 0.0073 0.0073
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0116 0.0718 0.1474
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0718 0.1705
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.0146 0.0147
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0094 0.0571 0.2406
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0083 0.0177
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0032 0.0138 0.0582
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0023 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Echinococcus granulosus nAChR subunit 0.0053 0.028 0.028
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0033 0.0146 0.0318
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0436 0.2943 0.2943
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Echinococcus granulosus mitogen activated protein kinase 0.0107 0.0658 0.0658
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0061 0.0061
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.038 0.0905
Trichomonas vaginalis importin beta-1, putative 0.0021 0.0059 0.0103
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.009 0.0539 0.0539
Schistosoma mansoni opsin-like receptor 0.0077 0.0451 0.0451
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0033 0.0146 0.0461
Loa Loa (eye worm) G-protein coupled receptor 0.0077 0.0451 0.107
Echinococcus multilocularis microtubule associated protein 2 0.1451 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0046 0.0075
Mycobacterium ulcerans transmembrane transport protein 0.0017 0.0035 0.0111
Plasmodium falciparum cGMP-dependent protein kinase 0.0015 0.0021 0.0051
Leishmania major ferredoxin, 2fe-2s-like protein 0.0023 0.0071 0.0072
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0033 0.0144 0.0607
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Trichomonas vaginalis Ferredoxin 3 0.0023 0.0071 0.0128
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0456 0.1507
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0014 0.0014 0.002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0077 0.0451 0.0451
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0436 0.2943 0.2943
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0116 0.0718 0.0718
Schistosoma mansoni lipoxygenase 0.0173 0.1119 0.1119
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0083 0.0177
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0083 0.0177
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0056 0.012
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0274 0.064
Mycobacterium ulcerans 6-phosphofructokinase 0.0118 0.0734 0.2323
Schistosoma mansoni metabotropic glutamate receptor 0.0045 0.0226 0.0226
Loa Loa (eye worm) TYRA-2 protein 0.0077 0.0451 0.107
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0398 0.2683 0.2683
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0734 0.1508
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0061 0.0061
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0085 0.0505 0.0505
Schistosoma mansoni glutamate synthase 0.0116 0.0718 0.0718
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0354 0.0354
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0014 0.0014 0.0009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0436 0.2943 0.9315
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0052 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0537
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0061 0.0061
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0014 0.0014 0.0014
Brugia malayi 6-phosphofructokinase 0.0118 0.0735 0.1763
Echinococcus multilocularis g protein coupled receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis serine protein kinase ATM 0.0018 0.0038 0.0038
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0083 0.0083
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0138 0.0874 0.2094
Schistosoma mansoni sulfide quinone reductase 0.0116 0.0718 0.0718
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0021 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0014 0.0014 0.0014
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0033 0.0146 0.0318
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0116 0.0718 0.0718
Brugia malayi hypothetical protein 0.0053 0.0282 0.0668
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0302 0.0609
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0061 0.014
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0045 0.0223 0.0526
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0059 0.0059
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.028 0.028
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0061 0.0061
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1218 0.838 0.8453
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) phosphatidylinositol 3 0.0094 0.0571 0.1359
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0033 0.0033
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0015
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.0292 0.0706
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0021 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0116 0.0718 0.0718
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0175 0.0344
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0211
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0134 0.0135
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0045 0.0223 0.0223
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0061 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0206 0.1347 0.3959
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.1176 0.2428
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.0021 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0038 0.0059
Schistosoma mansoni neuropeptide receptor 0.0077 0.0451 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Leishmania major hypothetical protein, conserved 0.0017 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0077 0.0447 0.1061
Loa Loa (eye worm) glutamate receptor 0.0021 0.006 0.0124
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.009 0.0539 0.0539
Echinococcus multilocularis 6 phosphofructokinase 0.0118 0.0734 0.0734
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Trypanosoma cruzi protein kinase A regulatory subunit 0.0014 0.0014 0.0014
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0436 0.0888
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0436 0.2943 0.711
Brugia malayi Bromodomain containing protein 0.0083 0.0491 0.1174
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0059 0.025
Trypanosoma brucei C-8 sterol isomerase, putative 0.04 0.2692 0.2716
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0014 0.0014 0.0014
Echinococcus multilocularis zinc finger protein 0.0023 0.0073 0.0073
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0223 0.0223
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0015 0.0021 0.0051
Echinococcus granulosus biogenic amine 5HT receptor 0.021 0.137 0.137
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0014 0.0034
Schistosoma mansoni 60S ribosomal protein L21 0.0016 0.0022 0.0022
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0014 0.0014 0.0034
Toxoplasma gondii NADPH-glutathione reductase 0.0436 0.2943 0.711
Schistosoma mansoni biogenic amine (5HT) receptor 0.021 0.137 0.137
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.038 0.038
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0077 0.0451 0.1077
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.028 0.0662
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.107 0.7354 0.7418
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.028 0.028
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0238 0.1568 0.4963
Trichomonas vaginalis inositol monophosphatase, putative 0.0033 0.0144 0.0279
Mycobacterium ulcerans oxidoreductase 0.0023 0.0071 0.0225
Brugia malayi putative neuropeptide receptor NPR1 0.0077 0.0451 0.1077
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0061 0.0061
Onchocerca volvulus 0.0138 0.0874 0.2554
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0083 0.0185
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1438 0.9913 1
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0436 0.2943 0.7105
Brugia malayi Cation transporter family protein 0.0053 0.028 0.0662
Brugia malayi hypothetical protein 0.0497 0.337 0.8138
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.038 0.0898
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.107 0.7354 0.7418
Loa Loa (eye worm) hypothetical protein 0.0138 0.0874 0.2094
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0023 0.0071 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1739 0.3601
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Treponema pallidum thioredoxin reductase (trxB) 0.0116 0.0718 0.2402
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0116 0.0718 0.1474
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.038 0.0384
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0306 0.0617
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0116 0.0718 0.0724
Echinococcus granulosus tyrosine protein kinase Lyn 0.0042 0.0205 0.0205
Loa Loa (eye worm) programmed cell death 8 0.0116 0.0718 0.1715
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0039 0.0183 0.0429
Schistosoma mansoni microtubule-associated protein tau 0.1451 1 1
Brugia malayi 6-phosphofructokinase 0.0118 0.0734 0.1761
Leishmania major NADH dehydrogenase, putative 0.0116 0.0718 0.0724
Echinococcus granulosus orexin receptor type 2 0.0077 0.0451 0.0451
Mycobacterium ulcerans epimerase 0.002 0.0056 0.0178
Giardia lamblia GTOR 0.0094 0.0571 0.1899
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0116 0.0718 0.3027
Echinococcus granulosus nAChR subunit 0.0028 0.0111 0.0111
Echinococcus multilocularis dro:myosuppressin receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0077 0.0451 0.0451
Echinococcus granulosus geminin 0.0356 0.239 0.239
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0317 0.2119 0.8937
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.028 0.0655
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0019 0.0046 0.0046
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0116 0.0718 0.0718
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0014 0.0014 0.0014
Leishmania major cytochrome p450-like protein 0.0052 0.0274 0.0276
Onchocerca volvulus 0.0045 0.0223 0.0621
Chlamydia trachomatis endonuclease IV 0.0078 0.0456 0.1507
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0198 0.0198
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0199 0.0199
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0071 0.0072
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0436 0.2943 1
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0098 0.0592 0.0592
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0104 0.0104
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1739 0.3601
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0608 0.414 1
Brugia malayi AKH receptor 0.0077 0.0451 0.1077
Schistosoma mansoni amine GPCR 0.0077 0.0451 0.0451
Leishmania major hypothetical protein, conserved 0.0014 0.0014 0.0014
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0033 0.0146 0.0461
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.0183 0.0361
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0033 0.0146 0.0318
Plasmodium vivax glutathione reductase, putative 0.0608 0.414 1
Brugia malayi neuropeptide F receptor 0.0077 0.0451 0.1077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0077 0.0451 0.0451
Onchocerca volvulus Putative nachr subunit 0.0053 0.028 0.0789
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0023 0.0071 0.0157
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0077 0.0451 0.0451
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0077 0.0451 0.0451
Toxoplasma gondii non-specific serine/threonine protein kinase 0.002 0.0052 0.0126
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Echinococcus granulosus serotonin receptor 0.0077 0.0451 0.0451
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0155 0.0991 0.3335
Trichomonas vaginalis Ferredoxin 6 0.0023 0.0071 0.0128
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0077 0.0451 0.0451
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0098 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.028 0.028
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0016 0.0016
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0734 0.3095
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0015 0.0015 0.0002
Onchocerca volvulus 0.0076 0.044 0.1266
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0014 0.0014 0.0014
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0116 0.0718 0.0718
Brugia malayi Uncoordinated protein 44 0.0015 0.0015 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.044 0.044
Treponema pallidum fructose-bisphosphate aldolase 0.0317 0.2119 0.7187
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0135 0.0327
Loa Loa (eye worm) TK protein kinase 0.0033 0.0142 0.032
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0171 0.0398
Brugia malayi FAT domain containing protein 0.0014 0.001 0.0009
Brugia malayi sulfakinin receptor protein 0.0077 0.0451 0.1077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0033 0.0146 0.0461
Echinococcus granulosus tm gpcr rhodopsin 0.0976 0.67 0.67
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Brugia malayi protein-tyrosine kinase 0.0037 0.017 0.0397
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1739 0.3601
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Echinococcus multilocularis somatostatin receptor 0.0077 0.0451 0.0451
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0658 0.135
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0056 0.01
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0023 0.0073 0.0073
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0116 0.0718 0.1734
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0056 0.0056
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0059 0.006
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0202 0.0202
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0033 0.0146 0.0318
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0059 0.006
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0014 0.0014 0.0009
Schistosoma mansoni hypothetical protein 0.0032 0.0138 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0061 0.0126
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0116 0.0718 0.1734
Trypanosoma cruzi cAMP response protein 1, putative 0.0014 0.0014 0.0014
Schistosoma mansoni ap endonuclease 0.002 0.0056 0.0056
Echinococcus multilocularis fmrfamide receptor 0.0077 0.0451 0.0451
Trypanosoma brucei unspecified product 0.0014 0.0014 0.0014
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0175 0.0177
Echinococcus multilocularis nAChR subunit 0.0028 0.0111 0.0111
Loa Loa (eye worm) neuropeptide F receptor 0.0077 0.0451 0.107
Trypanosoma brucei electron transfer protein, putative 0.0023 0.0071 0.0072
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0125 0.028
Trichomonas vaginalis set domain proteins, putative 0.0499 0.338 0.7016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0073 0.0153
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0116 0.0718 0.0718
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0059 0.0103
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0061 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0059 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Echinococcus granulosus 6 phosphofructokinase 0.0118 0.0734 0.0734
Leishmania major importin beta-1 subunit, putative 0.0021 0.0059 0.006
Schistosoma mansoni rab6-interacting 0.0041 0.0202 0.0202
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0033 0.0146 0.0461
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Onchocerca volvulus 0.0053 0.028 0.0789
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0134 0.0259
Loa Loa (eye worm) solute carrier family 6 member 4 0.0262 0.1738 0.4186
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0033 0.0079
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0014 0.0014 0.002
Onchocerca volvulus 0.0077 0.0451 0.1298
Onchocerca volvulus 0.0104 0.0637 0.1848
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0024 0.0031
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0436 0.2943 0.711
Entamoeba histolytica hypothetical protein 0.0032 0.0138 0.0582
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.017 0.017
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0135 0.0413
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0033 0.0033
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0116 0.0718 0.2272
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0023 0.0073 0.0131
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0077 0.0451 0.0451
Schistosoma mansoni glutamate synthase 0.0116 0.0718 0.0718
Echinococcus granulosus cytochrome P450 2K1 0.0033 0.0146 0.0146
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0033 0.0146 0.0461
Loa Loa (eye worm) hypothetical protein 0.0116 0.0718 0.1715
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0023 0.0071 0.0072
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0198 0.0198
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0014 0.0034
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0116 0.0718 0.2272
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0175 0.0175
Brugia malayi MH2 domain containing protein 0.0107 0.0658 0.1577
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Giardia lamblia [2Fe-2S] ferredoxin 0.0023 0.0071 0.0194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0116 0.0718 0.2293
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0026 0.0026
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0116 0.0718 0.2402
Echinococcus granulosus Adrenodoxin mitochondrial 0.0023 0.0071 0.0071
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0436 0.2943 0.71
Echinococcus granulosus neuropeptide s receptor 0.0545 0.3704 0.3704
Brugia malayi Cation transporter family protein 0.0053 0.028 0.0662
Schistosoma mansoni hypothetical protein 0.0017 0.0033 0.0033
Trichomonas vaginalis glutathione reductase, putative 0.0436 0.2943 0.6106
Echinococcus granulosus lamin dm0 0.0057 0.0308 0.0308
Brugia malayi glutamate synthase 0.0116 0.0718 0.1722
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.028 0.0655
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.054
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0033 0.0144 0.0348
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0734 0.1508
Loa Loa (eye worm) hypothetical protein 0.0054 0.029 0.0679
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0436 0.2943 0.9315
Trichomonas vaginalis apoptosis inducing factor, putative 0.0116 0.0718 0.1474
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0116 0.0718 0.0724
Loa Loa (eye worm) G-protein coupled receptor 0.0077 0.0451 0.107
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0061 0.0134
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0061 0.0061
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.009 0.0539 0.1288
Echinococcus granulosus neuropeptide receptor 0.0077 0.0451 0.0451
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0033 0.0079
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0039 0.0183 0.0185
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Schistosoma mansoni hypothetical protein 0.0116 0.0718 0.0718
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Onchocerca volvulus 0.0077 0.0451 0.1298
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.003 0.012 0.036
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0015 0.0014
Loa Loa (eye worm) cytochrome P450 0.0033 0.0146 0.033
Schistosoma mansoni biogenic amine (5HT) receptor 0.046 0.3112 0.3112
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0658 0.0664
Echinococcus granulosus neuropeptide Y receptor 0.0077 0.0451 0.0451
Giardia lamblia Glutamate synthase 0.0116 0.0718 0.2402
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0175 0.0175
Loa Loa (eye worm) phosphofructokinase 0.0118 0.0734 0.1754
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0023 0.0071 0.0194
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0101 0.0613 0.2585
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0561 0.3813 0.921
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0061 0.0134
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1438 0.9913 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0023 0.0073 0.0073
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0014 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Brugia malayi Importin beta-1 subunit 0.0026 0.0093 0.0211
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.028 0.0662
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0144 0.0145
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0116 0.0718 0.2402
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0083 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0039 0.0183 0.0421
Mycobacterium tuberculosis Probable dehydrogenase 0.0116 0.0718 0.1705
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0059 0.0059
Onchocerca volvulus 0.0024 0.0083 0.0203
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0134 0.0302
Mycobacterium ulcerans oxygenase 0.0023 0.0071 0.0225
Brugia malayi Cyclic-nucleotide gated cation channel 0.0023 0.0073 0.0161
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0059 0.0188
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0061 0.0134
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0053 0.028 0.028
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0282 0.0285
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Echinococcus granulosus peptide allatostatin:somatostatin 0.0077 0.0451 0.0451
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0107 0.0658 0.0664
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0056 0.0095
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0046 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0483 0.0483
Plasmodium falciparum glutathione reductase 0.0608 0.414 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0118 0.0734 0.1744
Onchocerca volvulus 0.0077 0.0451 0.1298
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0134 0.0259
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0048 0.0247 0.0576
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0734 0.1754
Loa Loa (eye worm) serotonin transporter b 0.0262 0.1738 0.4186
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0077 0.0451 0.0451
Schistosoma mansoni voltage-gated potassium channel 0.0092 0.0555 0.0555
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0261
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0116 0.0718 0.1705
Trichomonas vaginalis Ferredoxin 4 0.0023 0.0071 0.0128
Trypanosoma cruzi adrenodoxin precursor, putative 0.0023 0.0071 0.0072
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0116 0.0718 0.1705
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0292 0.0292
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0095 0.0095
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.029 0.0679
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0071 0.0072
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0354 0.0856
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0014 0.0014
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0175 0.0175
Brugia malayi metabotropic glutamate receptor type 2 0.0026 0.0096 0.0216
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0111 0.0254
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0083 0.0083
Toxoplasma gondii selenide, water dikinase 0.0116 0.0718 0.1734
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0202 0.0202
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0104 0.0104
Entamoeba histolytica Ran family GTPase 0.0019 0.0046 0.0194
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0014 0.0014 0.0034
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0282 0.0681
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0144 0.0145
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0061 0.0061
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0184 0.0184
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0033 0.0144 0.0279
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0039 0.0183 0.0185
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0223 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0081 0.0474 0.0967
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0263 0.1739 0.4193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0282 0.066
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0116 0.0718 0.1705
Echinococcus multilocularis neuropeptides capa receptor 0.0077 0.0451 0.0451
Echinococcus granulosus glutamate synthase 0.0116 0.0718 0.0718
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0083 0.0185
Echinococcus granulosus GPCR family 2 0.0017 0.0033 0.0033
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.028 0.028
Leishmania major DNA polymerase eta, putative 0.0021 0.0059 0.006
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0033 0.0079
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0175 0.0175
Schistosoma mansoni hypothetical protein 0.009 0.0539 0.0539
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1739 0.3601
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0198 0.0198
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Echinococcus granulosus alpha 1A adrenergic receptor 0.0077 0.0451 0.0451
Brugia malayi Melatonin receptor type 1A 0.0077 0.0451 0.1077
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0035 0.0155 0.0156
Schistosoma mansoni hypothetical protein 0.0356 0.239 0.239
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0073 0.0073
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0061 0.0061
Trypanosoma brucei ISWI complex protein 0.0017 0.0029 0.0029
Trypanosoma brucei cAMP response protein 1, putative 0.0014 0.0014 0.0014
Entamoeba histolytica thioredoxin reductase, putative 0.0116 0.0718 0.3027
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0308 0.0723
Leishmania major hypothetical protein, conserved 0.0023 0.0071 0.0072
Echinococcus multilocularis voltage gated potassium channel 0.003 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0026 0.0093 0.0204
Onchocerca volvulus 0.0077 0.0451 0.1298
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0056 0.0124
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0116 0.0718 0.1705
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0046 0.0075
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0061 0.0061
Echinococcus multilocularis glutamate synthase 0.0116 0.0718 0.0718
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0023 0.0071 0.0072
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0015 0.0015
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.028 0.0662
Loa Loa (eye worm) ACC-1 protein 0.0053 0.028 0.0655
Mycobacterium ulcerans dehydrogenase 0.0116 0.0718 0.2272
Entamoeba histolytica hypothetical protein 0.0032 0.0138 0.0582
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0061 0.0061
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0033 0.0146 0.0147
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0045 0.0226 0.0226
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.028 0.028
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0202 0.0466
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0571 0.1167
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0118 0.0734 0.2457
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0077 0.0451 0.0451
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0138 0.0874 0.0874
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0116 0.0718 0.1474
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0718 0.0724
Chlamydia trachomatis ferredoxin 0.0023 0.0071 0.0194
Echinococcus multilocularis lamin 0.0057 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0223 0.0223
Schistosoma mansoni nAChR subunit 0.0024 0.0083 0.0083
Mycobacterium leprae putative cytochrome p450 0.0033 0.0146 0.0448
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0015 0.0003
Brugia malayi larval opioid receptor 0.0077 0.0451 0.1077
Echinococcus granulosus mitogen activated protein kinase 3 0.0107 0.0658 0.0658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0537
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0261
Plasmodium falciparum ferrodoxin reductase-like protein 0.0116 0.0718 0.1734
Echinococcus multilocularis biogenic amine (5HT) receptor 0.046 0.3112 0.3112
Schistosoma mansoni hypothetical protein 0.0014 0.001 0.001
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0023 0.0071 0.0054
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0142 0.0142
Loa Loa (eye worm) ACC-1 protein 0.0053 0.028 0.0655
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0202 0.0202
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0015 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0046 0.0075
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0223 0.0223
Brugia malayi hypothetical protein 0.0041 0.0202 0.0473
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0039 0.0186 0.0188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Brugia malayi Protein kinase domain containing protein 0.0016 0.0022 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0033 0.0146 0.0318
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0073 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.1739 0.3601
Loa Loa (eye worm) hypothetical protein 0.04 0.2692 0.6496
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.017 0.017
Trypanosoma cruzi cAMP response protein 1 0.0014 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0039 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0012
Onchocerca volvulus 0.0053 0.028 0.0789
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0053 0.028 0.028
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0061 0.0134
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0001
Onchocerca volvulus 0.0045 0.0223 0.0621
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0085 0.0505 0.1207
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0039 0.0183 0.0443
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0083 0.0185
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0073 0.0073
Brugia malayi Dopamine receptor protein 2 0.0077 0.0451 0.1077
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0116 0.0718 0.1474
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0061 0.0061
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1218 0.838 0.8453
Echinococcus granulosus g protein coupled receptor 0.0077 0.0451 0.0451
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0023 0.0071 0.0172
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0077 0.0451 0.0451
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0046 0.0075
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0032 0.0134 0.0135
Echinococcus granulosus serine protein kinase ATM 0.0018 0.0038 0.0038
Schistosoma mansoni lipoxygenase 0.0248 0.1638 0.1638
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Brugia malayi Bromodomain containing protein 0.0042 0.0203 0.0475
Schistosoma mansoni hypothetical protein 0.009 0.0539 0.0539
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0033 0.0146 0.0318
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0155 0.0991 0.2368
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0116 0.0718 0.1474
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0049 0.0252 0.0594
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.028 0.028
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0061 0.0061
Brugia malayi PHD-finger family protein 0.0029 0.0113 0.0259
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0135 0.057
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0436 0.2943 0.711
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0116 0.0718 0.1705
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.028 0.028
Echinococcus granulosus neuropeptide receptor A26 0.0545 0.3704 0.3704
Echinococcus multilocularis neuropeptide s receptor 0.0545 0.3704 0.3704
Toxoplasma gondii ferredoxin, putative 0.0023 0.0071 0.0172
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0198 0.0198
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0116 0.0718 0.1734
Echinococcus multilocularis serotonin receptor 0.021 0.137 0.137
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0138 0.0874 0.0874
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0021 0.0021
Echinococcus granulosus inositol monophosphatase 1 0.0033 0.0144 0.0144
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.038 0.038
Schistosoma mansoni hypothetical protein 0.0017 0.0033 0.0033
Leishmania major ferric reductase, putative 0.0035 0.0155 0.0156
Brugia malayi Doublecortin family protein 0.0041 0.0202 0.0473
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0045 0.0224 0.0226
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0135 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0436 0.0888
Brugia malayi ecdysteroid receptor 0.0021 0.0061 0.0134
Treponema pallidum NADH oxidase 0.0436 0.2943 1
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0116 0.0718 0.0718
Loa Loa (eye worm) hypothetical protein 0.0114 0.0705 0.1685
Echinococcus granulosus thioredoxin glutathione reductase 0.0608 0.414 0.414
Giardia lamblia Thioredoxin reductase 0.0116 0.0718 0.2402
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0083 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Leishmania major hypothetical protein, conserved 0.0014 0.0014 0.0014
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0175 0.0549
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0116 0.0718 0.0718
Echinococcus multilocularis cpg binding protein 0.0033 0.0143 0.0143
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0033 0.0146 0.0318
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0061 0.0126
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0436 0.2943 0.71
Giardia lamblia DNA repair protein RAD52 0.0354 0.2371 0.8048
Plasmodium vivax importin-beta 2, putative 0.0026 0.0093 0.0226
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0116 0.0718 0.2272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0306 0.0617
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0018 0.0038 0.0038
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.028 0.0662
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0537
Plasmodium falciparum transporter, putative 0.0045 0.0223 0.054
Loa Loa (eye worm) hypothetical protein 0.0262 0.1738 0.4186
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0175 0.0175
Brugia malayi CXXC zinc finger family protein 0.0029 0.0117 0.0267
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0033 0.0146 0.0147
Trypanosoma brucei trypanothione reductase 0.0608 0.414 0.4176
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0061 0.0126
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0061 0.0061
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0263 0.1739 0.4189
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.028 0.028
Brugia malayi phosphofructokinase 0.0118 0.0734 0.1761
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.028 0.028
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0033 0.0146 0.0461
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0116 0.0718 0.1474
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0059 0.006
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0026 0.0026
Trypanosoma brucei cAMP binding protein, putative 0.0014 0.0014 0.0014
Loa Loa (eye worm) LGC-31 protein 0.0053 0.028 0.0655
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0014 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0356 0.239 0.239
Echinococcus multilocularis snurportin 1 0.0276 0.1832 0.1832
Brugia malayi neuropeptide F receptor 0.0077 0.0451 0.1077
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0135 0.0327
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0075 0.0437 0.044
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0198 0.0198
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0019 0.0046 0.0108
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Echinococcus granulosus tm gpcr rhodopsin 0.0077 0.0451 0.0451
Trypanosoma cruzi NADH dehydrogenase, putative 0.0116 0.0718 0.0724
Loa Loa (eye worm) hypothetical protein 0.0056 0.0301 0.0705
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0014 0.0014 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0658 0.135
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0033 0.0146 0.0318
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Brugia malayi G-protein coupled receptor 0.0077 0.0451 0.1077
Brugia malayi Tachykinin-like peptides receptor 99D 0.0077 0.0451 0.1077
Brugia malayi Cytochrome P450 family protein 0.0093 0.0559 0.1338
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0135 0.0849 0.2024
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0077 0.0451 0.0451
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0039 0.0183 0.0443
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0061 0.0134
Echinococcus granulosus g protein coupled receptor 0.0077 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0024 0.0079 0.0079
Echinococcus granulosus tyrosine kinase 0.0037 0.017 0.017
Onchocerca volvulus 0.0053 0.028 0.0789
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.036 0.036
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.0734 0.1508
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Schistosoma mansoni hypothetical protein 0.0033 0.0146 0.0146
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0033 0.0144 0.0145
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.028 0.0662
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0456 0.107
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0018 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0204 0.1334 0.3207
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0023 0.0071 0.0225
Onchocerca volvulus 0.0028 0.0111 0.0287
Schistosoma mansoni tyrosine kinase 0.0041 0.0198 0.0198
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0116 0.0718 0.0724
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0023 0.0071 0.0157
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0033 0.0065
Trypanosoma brucei unspecified product 0.0021 0.0059 0.006
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0071 0.0138
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0116 0.0718 0.3027
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0061 0.0061
Onchocerca volvulus 0.0077 0.0451 0.1298
Schistosoma mansoni hypothetical protein 0.0022 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0024 0.0031
Echinococcus multilocularis lamin dm0 0.0057 0.0308 0.0308
Loa Loa (eye worm) hypothetical protein 0.0041 0.0202 0.0466
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0046 0.0075
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0135 0.0327
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0077 0.0451 0.0451
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0059 0.006
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0077 0.0451 0.0451
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0155 0.0991 0.3137
Onchocerca volvulus 0.0041 0.0202 0.0557
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0073 0.0073
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0014 0.0014 0.0014
Echinococcus multilocularis RUN 0.0041 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0061 0.0134
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0061 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0056 0.0302 0.0609
Schistosoma mansoni ap endonuclease 0.002 0.0056 0.0056
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.003 0.0122 0.0281
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0094 0.0571 0.0571
Echinococcus multilocularis hyperpolarization activated cyclic 0.0023 0.0073 0.0073
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0077 0.0451 0.0451
Brugia malayi RNA, U transporter 1 0.0074 0.0425 0.1013
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0052 0.0274 0.0866
Trichomonas vaginalis Ferredoxin 1 0.0023 0.0071 0.0128
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0059 0.0109
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0014 0.0014 0.0014
Mycobacterium tuberculosis Possible oxygenase 0.0023 0.0071 0.0138
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0116 0.0718 0.1734
Onchocerca volvulus 0.0045 0.0223 0.0621
Leishmania major protein kinase A regulatory subunit, putative 0.0014 0.0014 0.0014
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0056 0.0056
Echinococcus multilocularis serotonin receptor 0.021 0.137 0.137
Schistosoma mansoni amine GPCR 0.0077 0.0451 0.0451
Treponema pallidum hypothetical protein 0.0115 0.071 0.2376
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0061 0.0061
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0039 0.0183 0.0185
Leishmania major DNA polymerase kappa, putative 0.0021 0.0059 0.006
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.1112 0.3259
Loa Loa (eye worm) neuropeptide F receptor 0.0077 0.0451 0.107
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0308 0.0723
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0079 0.0079
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0023 0.0071 0.0138
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0175 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0538
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0047 0.0091
Trypanosoma brucei NADH dehydrogenase 0.0116 0.0718 0.0724
Schistosoma mansoni nAChR subunit 0.0053 0.028 0.028
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0107 0.0658 0.1572
Echinococcus granulosus 7TM GPCR rhodopsin 0.0077 0.0451 0.0451
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0046 0.0075
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0033 0.0146 0.0461
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0045 0.0223 0.0714
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0033 0.0033
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0094 0.0571 0.0576
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.0526
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0044 0.0221 0.0513
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0135 0.0413
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0077 0.0451 0.0451
Echinococcus granulosus neuropeptide receptor 0.0077 0.0451 0.0451
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0467 0.3159 1
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0045 0.0223 0.0223
Brugia malayi SET domain containing protein 0.0015 0.002 0.0034
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0014 0.0014 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0262 0.1738 0.4191
Brugia malayi Serotonin receptor 0.0577 0.3923 0.9476
Trypanosoma cruzi NADH dehydrogenase, putative 0.0116 0.0718 0.0724
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0135 0.0261
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0085 0.0505 0.0505
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.028 0.0655
Schistosoma mansoni hypothetical protein 0.009 0.0539 0.0539
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0033 0.0146 0.0461
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Echinococcus multilocularis neuropeptide receptor 0.0077 0.0451 0.0451
Schistosoma mansoni biogenic amine receptor 0.0077 0.0451 0.0451
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0033 0.0146 0.0461
Echinococcus granulosus serotonin transporter 0.0262 0.1738 0.1738
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0038 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0061 0.0134
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0015 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0101 0.0619 0.0619
Echinococcus multilocularis neuropeptide FF receptor 2 0.0077 0.0451 0.0451
Onchocerca volvulus 0.0077 0.0451 0.1298
Onchocerca volvulus 0.0499 0.3381 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0033 0.0045
Trypanosoma cruzi ISWI complex protein 0.0017 0.0029 0.0029
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0332 0.0803
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0077 0.0451 0.0451
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.003 0.0122 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0274 0.064
Echinococcus granulosus RUN 0.0041 0.0202 0.0202
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0014 0.0014
Onchocerca volvulus 0.0077 0.0451 0.1298
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0039 0.0183 0.0361
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0061 0.0061
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0125 0.0287
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0198 0.0198
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0033 0.0144 0.0455
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0039 0.0183 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0061 0.0134
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1438 0.9913 1
Leishmania major ferredoxin 2fe-2s-like protein 0.0023 0.0071 0.0072
Echinococcus multilocularis mitogen activated protein kinase 3 0.0107 0.0658 0.0658
Schistosoma mansoni hypothetical protein 0.0077 0.0451 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0023 0.0073 0.0073
Schistosoma mansoni cpg binding protein 0.0033 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0015 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0976 0.67 0.67
Loa Loa (eye worm) hypothetical protein 0.0017 0.0033 0.0057
Echinococcus granulosus G protein coupled receptor 139 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.0526
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0014 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Leishmania major hypothetical protein, conserved 0.0116 0.0718 0.0724
Toxoplasma gondii hypothetical protein 0.0045 0.0223 0.054
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0436 0.2943 0.2969
Schistosoma mansoni inositol monophosphatase 0.0033 0.0144 0.0144
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0014 0.0014 0.0014
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0033 0.0033
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0093 0.0094
Treponema pallidum quinoline 2-oxidoreductase 0.0112 0.0692 0.2313
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0198 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0014 0.0014
Leishmania major acetoin dehydrogenase e3 component-like protein 0.107 0.7354 0.7418
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0041 0.0202 0.0202
Echinococcus multilocularis g protein coupled receptor 0.0077 0.0451 0.0451
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0018 0.0038 0.016
Trypanosoma brucei unspecified product 0.0014 0.0014 0.0014
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0223 0.0223
Trypanosoma cruzi hypothetical protein, conserved 0.0116 0.0718 0.0724
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0107 0.0658 0.0664
Echinococcus granulosus rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0116 0.0718 0.2272
Onchocerca volvulus 0.0077 0.0451 0.1298
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0017 0.0035 0.0051
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0039 0.0183 0.0429
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0436 0.2943 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.0354 0.0717
Brugia malayi Death domain containing protein 0.0015 0.0015 0.0022
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0185 0.0185
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0434 0.0434
Mycobacterium ulcerans hypothetical protein 0.0014 0.0014 0.0045
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0061 0.0061
Entamoeba histolytica hypothetical protein 0.0101 0.0613 0.2585
Schistosoma mansoni bromodomain containing protein 0.007 0.0403 0.0403
Toxoplasma gondii ferodoxin FD 0.0023 0.0071 0.0172
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0107 0.0658 0.0664
Brugia malayi hypothetical protein 0.011 0.0679 0.1627
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0018 0.0038 0.0038
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0111 0.0254
Loa Loa (eye worm) glutathione reductase 0.0608 0.414 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0116 0.0718 0.1474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0134 0.0259
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0032 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0268 0.0538
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Trypanosoma cruzi cytochrome P450, putative 0.0052 0.0274 0.0276
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Schistosoma mansoni alpha-1 adrenergic receptor 0.0077 0.0451 0.0451
Leishmania major hypothetical protein, conserved 0.0053 0.0282 0.0285
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0095 0.0095
Leishmania major protein kinase, putative 0.0015 0.0021 0.0021
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0033 0.0146 0.0147
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0135 0.0327
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0116 0.0718 0.1474
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0135 0.0849 0.2688
Loa Loa (eye worm) norepinephrine transporter 0.0262 0.1738 0.4186
Echinococcus granulosus cGMP dependent protein kinase 1 0.0015 0.0021 0.0021
Entamoeba histolytica protein kinase, putative 0.0033 0.0142 0.0597
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.032 0.2139 0.516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Brugia malayi hypothetical protein 0.0024 0.0083 0.0185
Echinococcus multilocularis expressed conserved protein 0.0015 0.0021 0.0021
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.0526
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0134 0.0309
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0069 0.0145
Schistosoma mansoni amine GPCR 0.0437 0.2951 0.2951
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0116 0.0718 0.0724
Echinococcus multilocularis mitogen activated protein kinase 0.0107 0.0658 0.0658
Brugia malayi Metabotropic glutamate receptor precursor. 0.0054 0.0287 0.0679
Brugia malayi RE15519p 0.0077 0.0451 0.1077
Schistosoma mansoni neuropeptide receptor 0.0077 0.0451 0.0451
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0061 0.014
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0073 0.0073
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0436 0.2943 0.9315
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0056 0.0176
Echinococcus granulosus dna polymerase kappa 0.0021 0.0059 0.0059
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0039 0.0183 0.0185
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0198 0.0198
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0436 0.0888
Onchocerca volvulus 0.011 0.0678 0.1971
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.028 0.0662
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.0138 0.0138
Onchocerca volvulus 0.0024 0.0083 0.0203
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0705 0.4814 1
Onchocerca volvulus 0.0077 0.0451 0.1298
Schistosoma mansoni inositol monophosphatase 0.0033 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0018 0.0038 0.0069
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0059 0.0103
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0059 0.0129
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0033 0.0146 0.0147
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0094 0.0571 0.0576
Echinococcus granulosus g protein coupled receptor 0.0077 0.0451 0.0451
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0334 0.0334
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0061 0.0126
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0282 0.0681
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0229
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.028 0.028
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0032 0.0134 0.0135
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0571 0.1167
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.028 0.0662
Onchocerca volvulus 0.0077 0.0451 0.1298
Schistosoma mansoni histamine h1 receptor 0.0077 0.0451 0.0451
Toxoplasma gondii target of rapamycin (TOR), putative 0.007 0.0402 0.0972
Trichomonas vaginalis Ferredoxin 7 0.0023 0.0071 0.0128
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0077 0.0451 0.0451
Schistosoma mansoni coup transcription factor 0.0021 0.0061 0.0061
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0023 0.0073 0.0073
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0436 0.2943 0.2969
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.0658 0.157
Loa Loa (eye worm) hypothetical protein 0.0527 0.3576 0.8635
Echinococcus multilocularis 0.0033 0.0146 0.0146
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0014 0.0014 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0053 0.028 0.028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0061 0.0061
Loa Loa (eye worm) AGC/PKG protein kinase 0.0015 0.0021 0.0028
Loa Loa (eye worm) hypothetical protein 0.011 0.0679 0.1621
Echinococcus multilocularis g protein coupled receptor 0.0077 0.0451 0.0451
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.028 0.028
Echinococcus granulosus hypothetical protein 0.0826 0.5659 0.5659
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0014 0.0014 0.002
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0085 0.0505 0.12
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.017 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0658 0.0658
Brugia malayi putative neuropeptide receptor 0.0077 0.0451 0.1077
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0033 0.0146 0.0461
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0094 0.0571 0.1365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0038 0.0059
Echinococcus granulosus g-protein coupled receptor 0.0077 0.0451 0.0451
Plasmodium vivax amine transporter, putative 0.0045 0.0223 0.054
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0436 0.2943 0.2943
Echinococcus granulosus voltage gated potassium channel 0.003 0.0122 0.0122
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.0734 0.0734
Leishmania major regulatory subunit of protein kinase a-like protein 0.0014 0.0014 0.0014
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0023 0.0071 0.0071
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0018 0.0038 0.0038
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0175 0.0175
Brugia malayi SRC-1 0.0041 0.0198 0.0464
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0056 0.0134
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0282 0.0285
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0059 0.0103
Schistosoma mansoni neuropeptide receptor 0.0077 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0211
Loa Loa (eye worm) hypothetical protein 0.0497 0.337 0.8137
Echinococcus multilocularis G-protein coupled receptor, putative 0.0077 0.0451 0.0451
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0083 0.0083
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0175 0.0177
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0037 0.0171 0.0391
Entamoeba histolytica hypothetical protein 0.0021 0.0059 0.0251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0134 0.0259
Trypanosoma brucei protein kinase A regulatory subunit 0.0014 0.0014 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0059 0.0129
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Onchocerca volvulus 0.0077 0.0451 0.1298
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0332 0.2224 0.7039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0436 0.0888
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0083 0.0083
Brugia malayi G-protein coupled receptor 0.0077 0.0451 0.1077
Toxoplasma gondii HEAT repeat-containing protein 0.0026 0.0093 0.0226
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0033 0.0146 0.0461
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0376 0.0376
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0456 0.11
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.038 0.0384
Brugia malayi hypothetical protein 0.0045 0.0223 0.0526
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0033 0.0079
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0033 0.0146 0.0461
Schistosoma mansoni survival motor neuron protein 0.0101 0.0619 0.0619
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0041 0.0199 0.0466
Mycobacterium ulcerans hypothetical protein 0.0014 0.0014 0.0045
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0033 0.0146 0.0461
Entamoeba histolytica hypothetical protein 0.0018 0.0038 0.016
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0107 0.0658 0.1591
Echinococcus granulosus zinc finger protein 0.0023 0.0073 0.0073
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0033 0.0033
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0436 0.2943 0.2969
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0199 0.0199
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0033 0.0146 0.0318
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0111 0.0111
Echinococcus granulosus neuropeptides capa receptor 0.0077 0.0451 0.0451
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0094 0.0571 0.0576
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0198 0.0198
Trypanosoma cruzi cAMP binding protein, putative 0.0014 0.0014 0.0014
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0042 0.0203 0.0469
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Loa Loa (eye worm) glutamate receptor 0.0054 0.0287 0.0672
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1438 0.9913 1
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0116 0.0718 0.2272
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0094 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Schistosoma mansoni hypothetical protein 0.0416 0.2805 0.2805
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.028 0.028
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0046 0.0046
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0077 0.0451 0.0451
Schistosoma mansoni hypothetical protein 0.0017 0.0033 0.0033
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0023 0.0071 0.0138
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.028 0.028
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0045 0.0223 0.0518
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Plasmodium falciparum glutathione reductase 0.0436 0.2943 0.711
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Giardia lamblia NADH oxidase lateral transfer candidate 0.0436 0.2943 1
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0116 0.0718 0.1734
Trichomonas vaginalis PIKK family atypical protein kinase 0.007 0.0402 0.0817
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0056 0.0056
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.0292 0.0295
Mycobacterium ulcerans hypothetical protein 0.0014 0.0014 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0077 0.0451 0.0451
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0039 0.0183 0.0183
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0292 0.0292
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.0138 0.0138
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0175 0.0738
Plasmodium vivax SET domain protein, putative 0.0063 0.0354 0.0856
Brugia malayi hypothetical protein 0.0077 0.0451 0.1077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0077 0.0451 0.0451
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0033 0.0033
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0033 0.0057
Onchocerca volvulus 0.0077 0.0451 0.1298
Schistosoma mansoni amine GPCR 0.0077 0.0451 0.0451
Echinococcus multilocularis importin subunit beta 1 0.0026 0.0093 0.0093
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0705 0.4814 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.0292 0.0674
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0033 0.0146 0.0318
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.0292 0.0292
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0111 0.0111
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0061 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0061 0.0126
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0059 0.0103
Mycobacterium ulcerans transcriptional regulatory protein 0.0014 0.0014 0.0045
Leishmania major hypothetical protein, conserved 0.0116 0.0718 0.0724
Brugia malayi Cation transporter family protein 0.0138 0.0874 0.21
Schistosoma mansoni lamin 0.0057 0.0308 0.0308
Echinococcus granulosus potassium voltage gated channel subfamily H 0.003 0.0122 0.0122
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0116 0.0718 0.0718
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.032 0.2139 0.516
Mycobacterium ulcerans hypothetical protein 0.0116 0.0718 0.2272
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0079 0.0079
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0082 0.0483 0.1147
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.028 0.0662
Brugia malayi Dopamine receptor 0.0077 0.0451 0.1077
Brugia malayi glutathione reductase 0.0608 0.414 1
Onchocerca volvulus 0.0029 0.0117 0.0304
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0033 0.0064
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0077 0.0451 0.0451
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0282 0.0681
Loa Loa (eye worm) hypothetical protein 0.0021 0.0059 0.0121
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0116 0.0718 0.0724
Leishmania major cyclic nucleotide-binding protein-like protein 0.0014 0.0014 0.0014
Leishmania major protein kinase, putative 0.0015 0.0021 0.0021
Echinococcus multilocularis dna polymerase eta 0.0021 0.0059 0.0059
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0059 0.0109
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0354 0.2371 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0061 0.0134
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0019 0.0046 0.0096
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Echinococcus multilocularis ferredoxin adrenodoxin 0.0023 0.0071 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0658 0.135
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0033 0.0146 0.0461
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0116 0.0718 0.2293
Onchocerca volvulus 0.0101 0.0619 0.1795
Onchocerca volvulus 0.0028 0.0111 0.0287
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0116 0.0718 0.2402
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0116 0.0718 0.1734
Schistosoma mansoni sodium/chloride dependent transporter 0.0046 0.023 0.023
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.1112 0.2294
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0033 0.0146 0.0461
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0332 0.2224 0.7039
Schistosoma mansoni intermediate filament proteins 0.0057 0.0308 0.0308
Schistosoma mansoni loxhd1 0.0041 0.0202 0.0202
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0018 0.0038 0.0038
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0248 0.1638 0.1638
Plasmodium falciparum thioredoxin reductase 0.0436 0.2943 0.711
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0033 0.0146 0.0318
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0056 0.0141
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0116 0.0718 0.0718
Mycobacterium ulcerans hypothetical protein 0.0014 0.0014 0.0045
Mycobacterium ulcerans electron transfer protein 0.0023 0.0071 0.0225
Trypanosoma cruzi importin beta-1 subunit, putative 0.0021 0.0059 0.006
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0436 0.2943 0.711
Loa Loa (eye worm) hypothetical protein 0.003 0.0122 0.0273
Plasmodium falciparum thioredoxin reductase 0.0608 0.414 1
Plasmodium falciparum amino acid transporter, putative 0.0045 0.0223 0.054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0042 0.0078
Echinococcus multilocularis sex peptide receptor 0.0077 0.0451 0.0451
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.028 0.0662
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0162 0.0162
Brugia malayi hypothetical protein 0.0041 0.0202 0.0473
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.028 0.0662
Echinococcus multilocularis neuropeptide receptor A26 0.0545 0.3704 0.3704
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0116 0.0718 0.1722
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0118 0.0734 0.2457
Trypanosoma cruzi ISWI complex protein 0.0017 0.0029 0.0029
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.0734 0.1754
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0056 0.0056
Trypanosoma cruzi C-8 sterol isomerase, putative 0.04 0.2692 0.2716
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0077 0.0451 0.0451
Leishmania major phosphatidylinositol 3-kinase, putative 0.0032 0.0134 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0061 0.0134
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0022 0.0022
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0073 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0059 0.006
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0023 0.0071 0.0225
Toxoplasma gondii endonuclease IV APN 0.0078 0.0456 0.11
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0436 0.2943 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0094 0.0571 0.0571
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0223 0.0223
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0053 0.028 0.0655
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0199 0.0199
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.0734 0.3095
Echinococcus granulosus histone lysine methyltransferase setb 0.0082 0.0483 0.0483
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1218 0.838 0.8453
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0059 0.006
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0033 0.0146 0.0461
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0014
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0039 0.0183 0.0443
Echinococcus multilocularis GPCR, family 2 0.0017 0.0033 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0059 0.006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.028 0.0662
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0135 0.0327
Loa Loa (eye worm) hypothetical protein 0.0262 0.1738 0.4186
Loa Loa (eye worm) hypothetical protein 0.021 0.137 0.3295
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0061 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0033 0.0146 0.0318
Loa Loa (eye worm) hypothetical protein 0.0024 0.0083 0.0177
Echinococcus multilocularis rhodopsin orphan GPCR 0.0077 0.0451 0.0451
Entamoeba histolytica disulphide oxidoreductase, putative 0.0116 0.0718 0.3027
Echinococcus granulosus dnaJ subfamily B 0.0416 0.2805 0.2805
Schistosoma mansoni hypothetical protein 0.0077 0.0451 0.0451
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0116 0.0718 0.1734
Echinococcus granulosus lamin 0.0057 0.0308 0.0308
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0559 0.1332
Schistosoma mansoni hypothetical protein 0.0077 0.0451 0.0451
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0014 0.0014 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.0118 0.0734 0.074
Schistosoma mansoni ran 0.0019 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0111 0.0246
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0111 0.0254
Trichomonas vaginalis mercuric reductase, putative 0.0436 0.2943 0.6106
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0033 0.0033
Echinococcus granulosus tachykinin peptides receptor 99D 0.0077 0.0451 0.0451
Loa Loa (eye worm) CYP4Cod1 0.0052 0.0274 0.064
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0202 0.0202
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0014 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0014 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0033 0.0146 0.0318
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0026 0.004
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0436 0.2943 0.711
Schistosoma mansoni hypothetical protein 0.0037 0.0171 0.0171
Brugia malayi Cytochrome P450 family protein 0.0052 0.0274 0.0647
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0056 0.0178
Brugia malayi CHD4 protein 0.0016 0.0026 0.0047
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0223 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0094 0.0571 0.1167
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.003 0.012 0.0256
Loa Loa (eye worm) hypothetical protein 0.0077 0.0451 0.107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0317 0.2119 0.4391
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0033 0.0146 0.0318
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.028 0.0662
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0135 0.0327
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0033 0.0146 0.0318
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0456 0.1087
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0056 0.0134
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.028 0.028
Echinococcus multilocularis dnaJ subfamily B 0.0416 0.2805 0.2805
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0033 0.0146 0.0461
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0056 0.0234
Brugia malayi hypothetical protein 0.0024 0.0083 0.0185
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.0658 0.157
Schistosoma mansoni DNA polymerase eta 0.0021 0.0059 0.0059
Mycobacterium leprae conserved hypothetical protein 0.002 0.0056 0.0143
Leishmania major GTP-binding protein, putative 0.0019 0.0046 0.0046
Onchocerca volvulus 0.0077 0.0451 0.1298
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0059 0.006
Toxoplasma gondii cytochrome p450 superfamily protein 0.0033 0.0146 0.0352
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0223 0.0223
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0014 0.0014 0.0014
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0032 0.0134 0.0135
Schistosoma mansoni netrin receptor unc5 0.0015 0.0015 0.0015
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.009 0.0539 0.0539

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) 0 uM Effective concentration against rat alpha3-beta4 nicotinic acetylcholine receptor; NA= insufficient response to obtain a value ChEMBL. 16005216
EC50 (binding) 0 uM Effective concentration against rat alpha4-beta2 nicotinic acetylcholine receptor; NA= insufficient response to obtain a value ChEMBL. 16005216
EC50 (binding) = 20 uM Effective concentration against rat alpha7 nicotinic acetylcholine receptor ChEMBL. 16005216
Imax (binding) 0 Maximal response against rat alpha3-beta4 nicotinic acetylcholine receptor; NA= insufficient response to obtain a value ChEMBL. 16005216
Imax (binding) 0 Maximal response against rat alpha4-beta2 nicotinic acetylcholine receptor; NA= insufficient response to obtain a value ChEMBL. 16005216
Imax (binding) = 0.26 Maximal response against rat alpha7 nicotinic acetylcholine receptor ChEMBL. 16005216
Ki (binding) = 0.6 uM Inhibition of [3H]-Nicotine binding to alpha4-beta2 nicotinic acetylcholine receptor of rat brain membrane ChEMBL. 16005216
Ki (binding) = 2.4 uM Inhibition of [3H]-MLA binding to rat alpha7 nicotinic acetylcholine receptor ChEMBL. 16005216

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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